Gene Symbol | VPS8 |
Entrez Gene ID | 851261 |
Full Name | CORVET complex membrane-binding subunit VPS8 |
Synonyms | FUN15,VPL8,VPT8 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » VPS8 cDNA ORF clone
Gene Symbol | VPS8 |
Entrez Gene ID | 851261 |
Full Name | CORVET complex membrane-binding subunit VPS8 |
Synonyms | FUN15,VPL8,VPT8 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001178149.1 | NP_009399.2 | CORVET complex membrane-binding subunit VPS8 |
Saccharomyces cerevisiae (baker's yeast) | VPS8 | NP_009399.2 |
Neurospora crassa | NCU02554 | XP_965685.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_01238 | XP_003714142.1 |
Kluyveromyces lactis | KLLA0C18491g | XP_453024.1 |
Eremothecium gossypii | AGOS_AFR002C | NP_985549.1 |
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
The nucleotide sequence of chromosome I from Saccharomyces cerevisiae.
Bussey H, Kaback DB, Zhong W, Vo DT, Clark MW, Fortin N, Hall J, Ouellette BF, Keng T, Barton AB
Proceedings of the National Academy of Sciences of the United States of America92(9)3809-13(1995 Apr)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
C-terminal alpha-helical segments of VPS3 and VPS8 are necessary for CORVET assembly and function.
Title: The N-terminal domains of Vps3 and Vps8 are critical for localization and function of the CORVET tethering complex on endosomes.
Data suggest that the Vps21 interaction is not essential for endosomal trafficking but may be important for some other aspect of Vps8 function.
Title: Mapping of Vps21 and HOPS binding sites in Vps8 and effect of binding site mutants on endocytic trafficking.
Vps8 interacts and cooperates with the activated Rab5 homolog Vps21 to induce the clustering of late endosomal membranes
Title: The CORVET subunit Vps8 cooperates with the Rab5 homolog Vps21 to induce clustering of late endosomal compartments.
The following VPS8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the VPS8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi00840 | |
Clone ID Related Accession (Same CDS sequence) | NM_001178149.1 | |
Accession Version | NM_001178149.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3825bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | CORVET complex membrane-binding subunit VPS8 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001133). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGGAGCAAA ATGGCCTTGA CCACGACAGC AGATCTAGCA TCGATACGAC TATTAATGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_009399.2 |
CDS | 1..3825 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001178149.1 |
1 | ATGGAGCAAA ATGGCCTTGA CCACGACAGC AGATCTAGCA TCGATACGAC TATTAATGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Life with 6000 genes. |
The nucleotide sequence of chromosome I from Saccharomyces cerevisiae. |