Gene Symbol | NTG1 |
Entrez Gene ID | 851218 |
Full Name | bifunctional N-glycosylase/AP lyase NTG1 |
Synonyms | FUN33,SCR1,ogg2 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » NTG1 cDNA ORF clone
Gene Symbol | NTG1 |
Entrez Gene ID | 851218 |
Full Name | bifunctional N-glycosylase/AP lyase NTG1 |
Synonyms | FUN33,SCR1,ogg2 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001178160.1 | NP_009387.1 | bifunctional N-glycosylase/AP lyase NTG1 |
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
The nucleotide sequence of chromosome I from Saccharomyces cerevisiae.
Bussey H, Kaback DB, Zhong W, Vo DT, Clark MW, Fortin N, Hall J, Ouellette BF, Keng T, Barton AB
Proceedings of the National Academy of Sciences of the United States of America92(9)3809-13(1995 Apr)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Both Ntg1 and its human homologue, NTHL1, can be SUMO-modified in response to oxidative stress.
Title: Identification of SUMO modification sites in the base excision repair protein, Ntg1.
the elements necessary for nuclear and mitochondrial localization of Ntg1 were identified, including a bipartite classical nuclear localization signal, a mitochondrial matrix targeting sequence and the classical nuclear protein import machinery.
Title: Regulation of base excision repair: Ntg1 nuclear and mitochondrial dynamic localization in response to genotoxic stress.
The intracellular localization of the Saccharomyces cerevisiae N-glycosylase/AP lyases, Ntg1 and Ntg2, in response to nuclear and mitochondrial oxidative stress, was determined.
Title: Dynamic compartmentalization of base excision repair proteins in response to nuclear and mitochondrial oxidative stress.
The superb activity of the 8-oxoguanine glycosylases Fpg, hOGG1, and Ntg1 toward removal of FapyG and FapyA in vitro suggests that these enzymes may act upon these oxidized lesions in vivo.
Title: Efficient removal of formamidopyrimidines by 8-oxoguanine glycosylases.
loss of Ntg1p suppresses mitochondrial point mutation rates, frameshifts and recombination rates
Title: Ntg1p, the base excision repair protein, generates mutagenic intermediates in yeast mitochondrial DNA.
The following NTG1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NTG1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi00804 | |
Clone ID Related Accession (Same CDS sequence) | NM_001178160.1 | |
Accession Version | NM_001178160.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1200bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | bifunctional N-glycosylase/AP lyase NTG1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001133). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGCAAAAGA TCAGTAAATA CTCATCTATG GCAATTCTGA GGAAAAGACC GCTGGTAAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_009387.1 |
CDS | 1..1200 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001178160.1 |
1 | ATGCAAAAGA TCAGTAAATA CTCATCTATG GCAATTCTGA GGAAAAGACC GCTGGTAAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Life with 6000 genes. |
The nucleotide sequence of chromosome I from Saccharomyces cerevisiae. |