Gene Symbol | PHO4 |
Entrez Gene ID | 850594 |
Full Name | phosphate-sensing transcription factor PHO4 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » PHO4 cDNA ORF clone
Gene Symbol | PHO4 |
Entrez Gene ID | 850594 |
Full Name | phosphate-sensing transcription factor PHO4 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001179999.1 | NP_116692.1 | phosphate-sensing transcription factor PHO4 |
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
Analysis of the nucleotide sequence of chromosome VI from Saccharomyces cerevisiae.
Murakami Y, Naitou M, Hagiwara H, Shibata T, Ozawa M, Sasanuma S, Sasanuma M, Tsuchiya Y, Soeda E, Yokoyama K
Nature genetics10(3)261-8(1995 Jul)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Pho85 and Pho4 regulated CLN2 expression under alkaline condition.
Title: The regulators of yeast PHO system participate in the transcriptional regulation of G1 cyclin under alkaline stress conditions.
Subsequent in-depth analysis of the inducible PHO5 gene reveals that topoisomerases are essential for binding of the Pho4p transcription factor to the PHO5 promoter, which is required for promoter nucleosome removal during activation.
Title: DNA Topoisomerases maintain promoters in a state competent for transcriptional activation in Saccharomyces cerevisiae.
The authors postulate that RPL12 has an extra-ribosomal function in modulating the transcription of genes that need Pho4p activation.
Title: Rpl12p affects the transcription of the PHO pathway high-affinity inorganic phosphate transporters and repressible phosphatases.
Pho4 activates some stress response genes, is required for G1 arrest caused by DNA damage, and is present in the nucleus even under high-Pi conditions to activate or repress transcription.
Title: Nutrient-regulated antisense and intragenic RNAs modulate a signal transduction pathway in yeast.
Pho4 binding to the SNZ1/SNO1 promoter is accompanied by alterations in chromatin structure, and Rpd3 histone deacetylase is required for the proper timing of SNZ1/SNO1 expression, while Asf1 histone chaperone is indispensable for their expression.
Title: Transcriptional repression by the Pho4 transcription factor controls the timing of SNZ1 expression.
The following PHO4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PHO4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi00272 | |
Clone ID Related Accession (Same CDS sequence) | NM_001179999.1 | |
Accession Version | NM_001179999.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 939bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | phosphate-sensing transcription factor PHO4 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001138). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGGGCCGTA CAACTTCTGA GGGAATACAC GGTTTTGTGG ACGATCTAGA GCCCAAGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_116692.1 |
CDS | 1..939 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001179999.1 |
1 | ATGGGCCGTA CAACTTCTGA GGGAATACAC GGTTTTGTGG ACGATCTAGA GCCCAAGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Life with 6000 genes. |
Analysis of the nucleotide sequence of chromosome VI from Saccharomyces cerevisiae. |