Gene Symbol | FAB1 |
Entrez Gene ID | 850574 |
Full Name | 1-phosphatidylinositol-3-phosphate 5-kinase |
Synonyms | SVL7 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » FAB1 cDNA ORF clone
Gene Symbol | FAB1 |
Entrez Gene ID | 850574 |
Full Name | 1-phosphatidylinositol-3-phosphate 5-kinase |
Synonyms | SVL7 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001179984.2 | NP_116674.2 | 1-phosphatidylinositol-3-phosphate 5-kinase |
Saccharomyces cerevisiae (baker's yeast) | FAB1 | NP_116674.2 |
Eremothecium gossypii | AGOS_AER188C | NP_985045.2 |
Kluyveromyces lactis | KLLA0D04598g | XP_453267.1 |
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
Analysis of the nucleotide sequence of chromosome VI from Saccharomyces cerevisiae.
Murakami Y, Naitou M, Hagiwara H, Shibata T, Ozawa M, Sasanuma S, Sasanuma M, Tsuchiya Y, Soeda E, Yokoyama K
Nature genetics10(3)261-8(1995 Jul)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Pho85/CDK5 provides protection against hyperosmotic stress and acts before long-term adaptation provided by Hog1. This protection requires the vacuolar/endolysosomal signaling lipid PI3,5P2 We show that Pho85/CDK5 directly phosphorylates and positively regulates the PI3P-5 kinase Fab1/PIKfyve complex and provide evidence that this regulation is conserved in mammalian cells.
Title: Early protection to stress mediated by CDK-dependent PI3,5P
Data suggest a model in which PtdIns(3)P 5-kinase protein Fab1/PIKfyve is dispensable to maintain vacuolar/lysosomal acidification.
Title: The Fab1/PIKfyve phosphoinositide phosphate kinase is not necessary to maintain the pH of lysosomes and of the yeast vacuole.
ATG18 and FAB1 are involved in dehydration stress tolerance in Saccharomyces cerevisiae.
Title: ATG18 and FAB1 are involved in dehydration stress tolerance in Saccharomyces cerevisiae.
Vac14 protein multimerization is a prerequisite step for Fab1 protein complex assembly and funct
Title: Vac14 protein multimerization is a prerequisite step for Fab1 protein complex assembly and function.
The crystal structure now unravels the presence of two distinct phosphoinositide-binding sites at the circumference of the seven bladed beta-propeller showing PtdINS3P and PtdIns(3,5)P2 proteins
Title: It takes two to tango: PROPPINs use two phosphoinositide-binding sites.
The following FAB1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FAB1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi00256 | |
Clone ID Related Accession (Same CDS sequence) | NM_001179984.2 | |
Accession Version | NM_001179984.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 6837bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | 1-phosphatidylinositol-3-phosphate 5-kinase | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001138). On Apr 26, 2011 this sequence version replaced NM_001179984.1. ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGTCATCGG AAGAACCCCA TGCATCTATA TCCTTTCCAG ATGGCTCACA TGTCCGGTCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_116674.2 |
CDS | 1..6837 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001179984.2 |
1 | ATGTCATCGG AAGAACCCCA TGCATCTATA TCCTTTCCAG ATGGCTCACA TGTCCGGTCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Life with 6000 genes. |
Analysis of the nucleotide sequence of chromosome VI from Saccharomyces cerevisiae. |