Gene Symbol | POL4 |
Entrez Gene ID | 850372 |
Full Name | DNA-directed DNA polymerase IV |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » POL4 cDNA ORF clone
Gene Symbol | POL4 |
Entrez Gene ID | 850372 |
Full Name | DNA-directed DNA polymerase IV |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001178727.1 | NP_009940.2 | DNA-directed DNA polymerase IV |
Saccharomyces cerevisiae (baker's yeast) | POL4 | NP_009940.2 |
Eremothecium gossypii | AGOS_AEL039W | NP_984822.1 |
Kluyveromyces lactis | KLLA0A11033g | XP_451480.1 |
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
The complete DNA sequence of yeast chromosome III.
Oliver SG, van der Aart QJ, Agostoni-Carbone ML, Aigle M, Alberghina L, Alexandraki D, Antoine G, Anwar R, Ballesta JP, Benit P
Nature357(6373)38-46(1992 May)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Our data suggest that the role of Tel1 in preventing break-induced chromosomal translocations can, to some extent, be due to its stimulating effect on gap-filling activity of Pol4 to repair DSBs in cis
Title: Yeast pol4 promotes tel1-regulated chromosomal translocations.
both yeast and human pol eta synthesize past the 3'-(m)C CPD in a >99% error-free manner, consistent with the highly water-exposed nature of the active site.
Title: Preparation of site-specific T=mCG cis-syn cyclobutane dimer-containing template and its error-free bypass by yeast and human polymerase ?.
model predicts that a unique function of Pol4 is to actively stabilize template strands that lack stacking continuity
Title: Evidence that base stacking potential in annealed 3' overhangs determines polymerase utilization in yeast nonhomologous end joining.
Pol4 is able to extend a 3'-end whose last bases are mismatched to the template strand
Title: Mismatch tolerance by DNA polymerase Pol4 in the course of nonhomologous end joining in Saccharomyces cerevisiae.
Pol4 is exclusively associated with the NHEJ pathway of double-stranded break repair
Title: DNA joint dependence of pol X family polymerase action in nonhomologous end joining.
The following POL4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the POL4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi00089 | |
Clone ID Related Accession (Same CDS sequence) | NM_001178727.1 | |
Accession Version | NM_001178727.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1749bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | DNA-directed DNA polymerase IV | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001135). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGTCTCTAA AGGGTAAATT TTTCGCCTTT TTACCTAATC CTAACACATC TTCCAATAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_009940.2 |
CDS | 1..1749 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001178727.1 |
1 | ATGTCTCTAA AGGGTAAATT TTTCGCCTTT TTACCTAATC CTAACACATC TTCCAATAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Life with 6000 genes. |
The complete DNA sequence of yeast chromosome III. |