Gene Symbol | MRC1 |
Entrez Gene ID | 850297 |
Full Name | chromatin-modulating protein MRC1 |
Synonyms | YCL060C |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » MRC1 cDNA ORF clone
Gene Symbol | MRC1 |
Entrez Gene ID | 850297 |
Full Name | chromatin-modulating protein MRC1 |
Synonyms | YCL060C |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001178704.1 | NP_009871.2 | chromatin-modulating protein MRC1 |
Saccharomyces cerevisiae (baker's yeast) | MRC1 | NP_009871.2 |
Eremothecium gossypii | AGOS_AFR745W | NP_986294.1 |
Kluyveromyces lactis | KLLA0C00484g | XP_452215.1 |
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
The complete DNA sequence of yeast chromosome III.
Oliver SG, van der Aart QJ, Agostoni-Carbone ML, Aigle M, Alberghina L, Alexandraki D, Antoine G, Anwar R, Ballesta JP, Benit P
Nature357(6373)38-46(1992 May)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Dia2-dependent degradation of Mrc1 is required for replication fork restart in a pathway that includes Sgs1 and Mph1.
Title: Degradation of Mrc1 promotes recombination-mediated restart of stalled replication forks.
Authors show that minisatellite length expansions are controlled by the products of the CSM3 and TOF1 genes, while contractions are controlled by MRC1.
Title: The role of CSM3, MRC1, and TOF1 in minisatellite stability and large loop DNA repair during meiosis in yeast.
Whereas Ddc1 and Dpb11 aid in replication-checkpoint activation, colocalization of Mec1 and Mrc1 at stalled replication forks promotes Rad53 activation sufficient to stabilize the replisome during transient replication stress.
Title: Colocalization of Mec1 and Mrc1 is sufficient for Rad53 phosphorylation in vivo.
Data show that that ISC1 controls cell morphology in combination with checkpoint regulators Swe1, Cdk1(CDC28), MRC1, TOF1, CSM3, RAD9 and Rad53.
Title: Cellular morphogenesis under stress is influenced by the sphingolipid pathway gene ISC1 and DNA integrity checkpoint genes in Saccharomyces cerevisiae.
cells deleted of MRC1, a gene implicated in replication fork stabilization and in the replication checkpoint pathway, maintained wild-type firing times despite over twofold lengthening of S phase
Title: MRC1-dependent scaling of the budding yeast DNA replication timing program.
The following MRC1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MRC1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi00026 | |
Clone ID Related Accession (Same CDS sequence) | NM_001178704.1 | |
Accession Version | NM_001178704.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3291bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | chromatin-modulating protein MRC1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001135). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGGATGATG CCTTGCATGC TTTGTCCTCG TTGACTGCAA AGAAGAGAAC TACCACCTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_009871.2 |
CDS | 1..3291 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001178704.1 |
1 | ATGGATGATG CCTTGCATGC TTTGTCCTCG TTGACTGCAA AGAAGAGAAC TACCACCTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Life with 6000 genes. |
The complete DNA sequence of yeast chromosome III. |