Sos2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Sos2
Entrez Gene ID	85384
Full Name	SOS Ras/Rho guanine nucleotide exchange factor 2
Synonyms	Sos1
General protein information	Preferred Names SOS Ras/Rho guanine nucleotide exchange factor 2 Names son of sevenless homolog 2 son of sevenless 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 6 Map Location: 6q24
Summary	mRNA expression increases after chronic clozapine treatment in the prefrontal cortex; may play a role in synaptic function [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006240184.3	XP_006240246.1	son of sevenless homolog 2 isoform X2
NM_001135561.1	NP_001129033.1	son of sevenless homolog 2
XM_008764721.1	XP_008762943.1	son of sevenless homolog 2 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	SOS2	NP_008870.2
Canis lupus familiaris (dog)	SOS2	XP_005623436.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP009180	XP_319944.4
Pan troglodytes (chimpanzee)	SOS2	XP_003314439.2
	SOS2	XP_001099864.1
Danio rerio (zebrafish)	sos2	XP_690171.2
Bos taurus (cattle)	SOS2	XP_002707757.2
Mus musculus (house mouse)	Sos2	NP_001129031.1
Rattus norvegicus (Norway rat)	Sos2	NP_001129033.1
Gallus gallus (chicken)	SOS2	XP_421461.4
Xenopus tropicalis (tropical clawed frog)	sos2	XP_002938172.2

Gene Ontology
Bibliography

Related articles in PubMed

Functional redundancy of Sos1 and Sos2 for lymphopoiesis and organismal homeostasis and survival.
Baltan?s FC, P?rez-Andr?s M, Ginel-Picardo A, Diaz D, Jimeno D, Liceras-Boillos P, Kortum RL, Samelson LE, Orfao A, Santos E
Molecular and cellular biology33(22)4562-78(2013 Nov)

IL-6/IL-6 receptor system and its role in physiological and pathological conditions.
Mihara M, Hashizume M, Yoshida H, Suzuki M, Shiina M
Clinical science (London, England : 1979)122(4)143-59(2012 Feb)

Src-dependent TrkA transactivation is required for pituitary adenylate cyclase-activating polypeptide 38-mediated Rit activation and neuronal differentiation.
Shi GX, Jin L, Andres DA
Molecular biology of the cell21(9)1597-608(2010 May)

EGF-ERBB signalling: towards the systems level.
Citri A, Yarden Y
Nature reviews. Molecular cell biology7(7)505-16(2006 Jul)

Local phosphatidylinositol 3,4,5-trisphosphate accumulation recruits Vav2 and Vav3 to activate Rac1/Cdc42 and initiate neurite outgrowth in nerve growth factor-stimulated PC12 cells.
Aoki K, Nakamura T, Fujikawa K, Matsuda M
Molecular biology of the cell16(5)2207-17(2005 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Sam68 associates with the SH3 domains of Grb2 recruiting GAP to the Grb2-SOS complex in insulin receptor signaling
Title: Sam68 associates with the SH3 domains of Grb2 recruiting GAP to the Grb2-SOS complex in insulin receptor signaling.

The following Sos2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Sos2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa29387	XM_006240184.3 Latest version!	Rattus norvegicus SOS Ras/Rho guanine nucleotide exchange factor 2 (Sos2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
ORa43874	XM_008764721.1 Latest version!	Rattus norvegicus SOS Ras/Rho guanine nucleotide exchange factor 2 (Sos2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$643.30 $919.00
ORa12010	NM_001135561.1 Latest version!	Rattus norvegicus SOS Ras/Rho guanine nucleotide exchange factor 2 (Sos2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$979.30 $1399.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Sos2 ( XM_006240184.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006240246.1 Rattus norvegicus SOS Ras/Rho guanine nucleotide exchange factor 2 (Sos2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa29387
Clone ID Related Accession (Same CDS sequence)	XM_006240184.3
Accession Version	XM_006240184.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3486bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	son of sevenless homolog 2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005105.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006240184.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACATGT TTGACCAGGA TGACGATATA GGCTTGGTTT CTCTCTGTGA AGAGGAACCT 
TGTTCTTCTG GTGAGCTAAA CTATTATGAC CTTGTTAGAA CTGAAATCGC AGAAGAAAGA 
CAGTATCTAC GGGAACTGAA TATGATCATT AAAGTATTCC GGGAAGCCTT TCTTTCAGAC 
AAAAAGTTGT TCAAGTCTTC TGAAATTGAA AAGATTTTCA GTAACATTTC AGATATACAT 
GAACTGACTG TGAAACTTTT AGGTTTGATT GAAGACACAG TAGAAATGAC AGATGAAAGC 
AGTCCTCACC CGCTAGCTGG TAGCTGCTTT GAAGATTTAG CAGAGGAGCA GGCTTTTGAC 
CCCTATGAAA CGTTATCACA GGACATTCTT GCTCCAGAGT TTAATGACCA CTTCAGCAAG 
TTGATGGCCA GACCTGCAGT TGCTCTGCAC TTTCAGTCCA TTGCTGACGG CTTTAAGGAG 
GCTGTTCGAT ATGTCCTTCC GCGCCTCATG CTGGTGCCGG TGTATCATTG TTGGCATTAC 
TTTGAATTAT TAAAGCAGTT GAAAGCATGT AGCGAAGAAC AGGAAGACCG AGAGTGTTTG 
AATCAGGCTA TCACTGCCCT CATGAACCTC CAAGGCAGCA TGGACCGGAT TTACAAGCAG 
CACTCGCCAA GGCGCCGGCC AGGGGATCCT GTTTGCCTTT TTTACAATCG TCAATTAAGA 
AGCAAGCACC TGGCTATCAA AAAAATGAAT GAAATTCAGA AAAACATTGA TGGGTGGGAA 
GGCAAAGATA TTGGACAGTG TTGTAATGAG TTCATAATGG AAGGACCATT GACCAGAATT 
GGTGCTAAGC ATGAAAGGCA TATTTTCCTC TTCGATGGCT TAATGATCAG CTGTAAACCC 
AATCATTGCC AGACTCGACT TCCAGGGTAT AGTAGTGCAG AATACAGGTT AAAAGAGAAG 
TTTGTCATGA GGAAAATTCA AATCTGTGAT AAAGAAGACG CTTGTGAATA CAAACATGCT 
TTTGAATTAG TATCCAAAGA TGAAAACAGT GTAATATTTG CTGCCAAGTC AGCTGAAGAG 
AAAAACAACT GGATGGCAGC CCTTATCTCC CTTCACTATC GGAGCACTCT AGATAGAATG 
CTGGACTCTG TGTTACTGAA AGAGGAGAAC GAGCAGCCCC TGCGGCTACC GCGGCCAGAC 
GTGTACCGCT TCGTGGTGAC AGACTCAGAG GAGAACATAG TTTTTGAAGA CAACTTGCAA 
AGCAGAAGTG GAATCCCCAT TATTAAAGGA GGCACCGTGG TGAAACTGAT CGAAAGGCTA 
ACATATCACA TGTATGCAGA TCCCAATTTT GTTCGTACTT TCCTTACTAC GTATCGTTCA 
TTTTGTAAGC CACAGGAATT GCTAAGCTTG CTGATAGAAC GGTTTGAAAT TCCAGATCCA 
GAGCCTACTG AGGCCGACAA ACTGGCGCTA GAGAAAGGCG AGCAGCCAAT CAGCGCAGAT 
CTGAAAAGAT TCCGCAAGGA ATATGTCCAA CCCGTGCAAC TTAGGGTCTT GAATGTCTTT 
CGCCACTGGG TTGAGCATCA TTTTTATGAC TTTGAAAGAG ACTTGGAATT GCTTGAAAGA 
CTGGAAGCCT TCATTTCAAG TGTAAGAGGG AAAGCCATGA AGAAGTGGGT AGAATCCATT 
GCTAAAATCA TCAAGAGGAA GAAGCAAGCT CAGGCCAATG GAGTAAGCCA TAATATCACC 
TTTGAAAGTC CGCCTCCACC GGTTGAATGG CACATAAGTA GGGCGGGACA GTCTGAAACC 
TTTGACCTTA TGACACTTCA TCCCATAGAG ATTGCACGGC AGTTAACACT CTTGGAATCT 
GATCTCTACA GGAGAGTCCA GCCTTCTGAA CTTGTAGGGA GTGTCTGGAC CAAAGAAGAT 
AAAGAAATAA ATTCTCCAAA TCTATTAAAA ATGATTCGCC ATACAACAAA CCTCACTTTG 
TGGTTTGAAA AATGCATTGT GGAAGCAGAA AACTTTGAAG AACGGGTGGC AGTGCTCAGC 
AGAATAGTAG AAATTCTGCA AGTGTTTCAA GATCTGAATA ATTTCAATGG CGTGTTGGAG 
ATAGTCAGTG CAGTCAATTC AGTGTCAGTG TACAGACTAG ACCACACATT TGAGGCATTG 
CAGGAAAGGA AGCGGAGAGT TTTGGATGAC GCTGTGGAAT TAAGTCAGGA TCACTTTAAA 
AAATACCTAG TAAAACTTAA ATCAATCAAT CCACCTTGTG TGCCTTTTTT TGGAATATAT 
TTAACAAATA TTCTGAAGAC TGAAGAAGGG AACAGCGACT TTCTAAAGAG GAAAGGGAAA 
GATTTGATCA ATTTCAGTAA GAGGAGAAAA GTGGCTGAAA TAACCGGAGA GATTCAGCAG 
TATCAGAACC AACCATACTG CTTACGGACA GAACCAGAGA TGAGGAGATT CTTTGAAAAC 
CTCAATCCCA TGGGACTTTT ATCTGAAAAA GAGTTTACAG ATTATTTGTT CAACAAATCT 
CATGAAATTG AACCCCGAAA CTGCAAACAA CCACCTCGAT TTCCTAGGAA GTCAACCTTT 
TCCTTAAAAT CTCCTGGAAT AAGGCCCAAT GCCAGCCGCC ATGGCTCTAC CTCAGGCACG 
TTCCGAGGTC ACCCAACCCC TCTGGAAAGG GAGCCTTATA AGATAAGCTT TAGCAGGATC 
GCCGAGACGG AGCTAGAATC CACGGTGTCA GCACCGACAT CTCCCAACAC CCCATCCACC 
CCACCTGTGT CTGCTTCTTC AGACCACAGC GTGTTTCTAG ATGTGGACCT CAATAGCTCC 
TGTGGCAGCA ATACCATCTT TGCTCCAGTC CTCTTGCCAC ACTCAAAGTC TTTCTTCAGC 
TCATGTGGAA GTCTACACAA ACTGAGTGAA GAGCCACTAG TTCCTCCTCC GCTTCCCCCT 
CGGAAAAAGT TTGATCACGA TGCTCCGAAC TCCAAGGGAG CTATGAAATC GGATGATGAC 
CCTCCTGCTA TTCCACCAAG ACAACCCCCT CCTCCAAAGG TAAAGCCAAG AGCTCCTGTC 
CTCACGGGTA CATTTGAAGG GCCTGTGCCC AGTCCACCTC CACCTCCTCC CAGAGACCCT 
CTTCCTGATA CTCCTCCACC AGTTCCTCTT CGGCCTCCGG AACACTTTAT AAACTGTCCG 
TTTAATCTCC AGCCGCCTCC GCTGGGACAT CCTCACAGAG ACCCAGACTG GCTCAGAGAC 
GTTAGCACAT GCCCTAATTC ACCAAGCACT CCTCCCCCTA CGCCCTCGCC ACGGATTCCA 
CGCAGATGCC ATTTGCCCAG CCCCAGTCAC AACAATCTTG CTCACCCTCC AGCTCCTCCC 
GTTCCACCAA GGCAGAATTC AAGCCCTCAC CTACCAAAAC TGCCACCAAA GACTTACAAG 
CGGGAGCTTT CACACCCGCC ATTGTACAGA CTACCTTTGT TTGAAAATGC AGAAACTCCT 
CAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006240246.1
CDS	1063..4548
Translation	MDMFDQDDDIGLVSLCEEEPCSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDKKLFKSSEIEKIFSNISDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDILAPEFNDHFSKLMARPAVALHFQSIADGFKEAVRYVLPRLMLVPVYHCWHYFELLKQLKACSEEQEDRECLNQAITALMNLQGSMDRIYKQHSPRRRPGDPVCLFYNRQLRSKHLAIKKMNEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKPNHCQTRLPGYSSAEYRLKEKFVMRKIQICDKEDACEYKHAFELVSKDENSVIFAAKSAEEKNNWMAALISLHYRSTLDRMLDSVLLKEENEQPLRLPRPDVYRFVVTDSEENIVFEDNLQSRSGIPIIKGGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPDPEPTEADKLALEKGEQPISADLKRFRKEYVQPVQLRVLNVFRHWVEHHFYDFERDLELLERLEAFISSVRGKAMKKWVESIAKIIKRKKQAQANGVSHNITFESPPPPVEWHISRAGQSETFDLMTLHPIEIARQLTLLESDLYRRVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEAENFEERVAVLSRIVEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRRVLDDAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNSDFLKRKGKDLINFSKRRKVAEITGEIQQYQNQPYCLRTEPEMRRFFENLNPMGLLSEKEFTDYLFNKSHEIEPRNCKQPPRFPRKSTFSLKSPGIRPNASRHGSTSGTFRGHPTPLEREPYKISFSRIAETELESTVSAPTSPNTPSTPPVSASSDHSVFLDVDLNSSCGSNTIFAPVLLPHSKSFFSSCGSLHKLSEEPLVPPPLPPRKKFDHDAPNSKGAMKSDDDPPAIPPRQPPPPKVKPRAPVLTGTFEGPVPSPPPPPPRDPLPDTPPPVPLRPPEHFINCPFNLQPPPLGHPHRDPDWLRDVSTCPNSPSTPPPTPSPRIPRRCHLPSPSHNNLAHPPAPPVPPRQNSSPHLPKLPPKTYKRELSHPPLYRLPLFENAETPQ

Target ORF information:

RefSeq Version	XM_006240184.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus SOS Ras/Rho guanine nucleotide exchange factor 2 (Sos2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006240184.3

ORF Insert Sequence:

ATGGACATGT TTGACCAGGA TGACGATATA GGCTTGGTTT CTCTCTGTGA AGAGGAACCT 
TGTTCTTCTG GTGAGCTAAA CTATTATGAC CTTGTTAGAA CTGAAATCGC AGAAGAAAGA 
CAGTATCTAC GGGAACTGAA TATGATCATT AAAGTATTCC GGGAAGCCTT TCTTTCAGAC 
AAAAAGTTGT TCAAGTCTTC TGAAATTGAA AAGATTTTCA GTAACATTTC AGATATACAT 
GAACTGACTG TGAAACTTTT AGGTTTGATT GAAGACACAG TAGAAATGAC AGATGAAAGC 
AGTCCTCACC CGCTAGCTGG TAGCTGCTTT GAAGATTTAG CAGAGGAGCA GGCTTTTGAC 
CCCTATGAAA CGTTATCACA GGACATTCTT GCTCCAGAGT TTAATGACCA CTTCAGCAAG 
TTGATGGCCA GACCTGCAGT TGCTCTGCAC TTTCAGTCCA TTGCTGACGG CTTTAAGGAG 
GCTGTTCGAT ATGTCCTTCC GCGCCTCATG CTGGTGCCGG TGTATCATTG TTGGCATTAC 
TTTGAATTAT TAAAGCAGTT GAAAGCATGT AGCGAAGAAC AGGAAGACCG AGAGTGTTTG 
AATCAGGCTA TCACTGCCCT CATGAACCTC CAAGGCAGCA TGGACCGGAT TTACAAGCAG 
CACTCGCCAA GGCGCCGGCC AGGGGATCCT GTTTGCCTTT TTTACAATCG TCAATTAAGA 
AGCAAGCACC TGGCTATCAA AAAAATGAAT GAAATTCAGA AAAACATTGA TGGGTGGGAA 
GGCAAAGATA TTGGACAGTG TTGTAATGAG TTCATAATGG AAGGACCATT GACCAGAATT 
GGTGCTAAGC ATGAAAGGCA TATTTTCCTC TTCGATGGCT TAATGATCAG CTGTAAACCC 
AATCATTGCC AGACTCGACT TCCAGGGTAT AGTAGTGCAG AATACAGGTT AAAAGAGAAG 
TTTGTCATGA GGAAAATTCA AATCTGTGAT AAAGAAGACG CTTGTGAATA CAAACATGCT 
TTTGAATTAG TATCCAAAGA TGAAAACAGT GTAATATTTG CTGCCAAGTC AGCTGAAGAG 
AAAAACAACT GGATGGCAGC CCTTATCTCC CTTCACTATC GGAGCACTCT AGATAGAATG 
CTGGACTCTG TGTTACTGAA AGAGGAGAAC GAGCAGCCCC TGCGGCTACC GCGGCCAGAC 
GTGTACCGCT TCGTGGTGAC AGACTCAGAG GAGAACATAG TTTTTGAAGA CAACTTGCAA 
AGCAGAAGTG GAATCCCCAT TATTAAAGGA GGCACCGTGG TGAAACTGAT CGAAAGGCTA 
ACATATCACA TGTATGCAGA TCCCAATTTT GTTCGTACTT TCCTTACTAC GTATCGTTCA 
TTTTGTAAGC CACAGGAATT GCTAAGCTTG CTGATAGAAC GGTTTGAAAT TCCAGATCCA 
GAGCCTACTG AGGCCGACAA ACTGGCGCTA GAGAAAGGCG AGCAGCCAAT CAGCGCAGAT 
CTGAAAAGAT TCCGCAAGGA ATATGTCCAA CCCGTGCAAC TTAGGGTCTT GAATGTCTTT 
CGCCACTGGG TTGAGCATCA TTTTTATGAC TTTGAAAGAG ACTTGGAATT GCTTGAAAGA 
CTGGAAGCCT TCATTTCAAG TGTAAGAGGG AAAGCCATGA AGAAGTGGGT AGAATCCATT 
GCTAAAATCA TCAAGAGGAA GAAGCAAGCT CAGGCCAATG GAGTAAGCCA TAATATCACC 
TTTGAAAGTC CGCCTCCACC GGTTGAATGG CACATAAGTA GGGCGGGACA GTCTGAAACC 
TTTGACCTTA TGACACTTCA TCCCATAGAG ATTGCACGGC AGTTAACACT CTTGGAATCT 
GATCTCTACA GGAGAGTCCA GCCTTCTGAA CTTGTAGGGA GTGTCTGGAC CAAAGAAGAT 
AAAGAAATAA ATTCTCCAAA TCTATTAAAA ATGATTCGCC ATACAACAAA CCTCACTTTG 
TGGTTTGAAA AATGCATTGT GGAAGCAGAA AACTTTGAAG AACGGGTGGC AGTGCTCAGC 
AGAATAGTAG AAATTCTGCA AGTGTTTCAA GATCTGAATA ATTTCAATGG CGTGTTGGAG 
ATAGTCAGTG CAGTCAATTC AGTGTCAGTG TACAGACTAG ACCACACATT TGAGGCATTG 
CAGGAAAGGA AGCGGAGAGT TTTGGATGAC GCTGTGGAAT TAAGTCAGGA TCACTTTAAA 
AAATACCTAG TAAAACTTAA ATCAATCAAT CCACCTTGTG TGCCTTTTTT TGGAATATAT 
TTAACAAATA TTCTGAAGAC TGAAGAAGGG AACAGCGACT TTCTAAAGAG GAAAGGGAAA 
GATTTGATCA ATTTCAGTAA GAGGAGAAAA GTGGCTGAAA TAACCGGAGA GATTCAGCAG 
TATCAGAACC AACCATACTG CTTACGGACA GAACCAGAGA TGAGGAGATT CTTTGAAAAC 
CTCAATCCCA TGGGACTTTT ATCTGAAAAA GAGTTTACAG ATTATTTGTT CAACAAATCT 
CATGAAATTG AACCCCGAAA CTGCAAACAA CCACCTCGAT TTCCTAGGAA GTCAACCTTT 
TCCTTAAAAT CTCCTGGAAT AAGGCCCAAT GCCAGCCGCC ATGGCTCTAC CTCAGGCACG 
TTCCGAGGTC ACCCAACCCC TCTGGAAAGG GAGCCTTATA AGATAAGCTT TAGCAGGATC 
GCCGAGACGG AGCTAGAATC CACGGTGTCA GCACCGACAT CTCCCAACAC CCCATCCACC 
CCACCTGTGT CTGCTTCTTC AGACCACAGC GTGTTTCTAG ATGTGGACCT CAATAGCTCC 
TGTGGCAGCA ATACCATCTT TGCTCCAGTC CTCTTGCCAC ACTCAAAGTC TTTCTTCAGC 
TCATGTGGAA GTCTACACAA ACTGAGTGAA GAGCCACTAG TTCCTCCTCC GCTTCCCCCT 
CGGAAAAAGT TTGATCACGA TGCTCCGAAC TCCAAGGGAG CTATGAAATC GGATGATGAC 
CCTCCTGCTA TTCCACCAAG ACAACCCCCT CCTCCAAAGG TAAAGCCAAG AGCTCCTGTC 
CTCACGGGTA CATTTGAAGG GCCTGTGCCC AGTCCACCTC CACCTCCTCC CAGAGACCCT 
CTTCCTGATA CTCCTCCACC AGTTCCTCTT CGGCCTCCGG AACACTTTAT AAACTGTCCG 
TTTAATCTCC AGCCGCCTCC GCTGGGACAT CCTCACAGAG ACCCAGACTG GCTCAGAGAC 
GTTAGCACAT GCCCTAATTC ACCAAGCACT CCTCCCCCTA CGCCCTCGCC ACGGATTCCA 
CGCAGATGCC ATTTGCCCAG CCCCAGTCAC AACAATCTTG CTCACCCTCC AGCTCCTCCC 
GTTCCACCAA GGCAGAATTC AAGCCCTCAC CTACCAAAAC TGCCACCAAA GACTTACAAG 
CGGGAGCTTT CACACCCGCC ATTGTACAGA CTACCTTTGT TTGAAAATGC AGAAACTCCT 
CAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Sos2 ( XM_008764721.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008762943.1 Rattus norvegicus SOS Ras/Rho guanine nucleotide exchange factor 2 (Sos2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa43874
Clone ID Related Accession (Same CDS sequence)	XM_008764721.1
Accession Version	XM_008764721.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3903bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	son of sevenless homolog 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005105.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGCAGG CGCCGCAGCC CTACGAGTTC TTCAGCGAAG AGAACAGCCC GAAATGGCGG 
GGACTGTTGG TCCCGGCCCT GCGGAAGGTT CAGGAGCAAG TGCACCCCAC CCTGTCGGCT 
AACGAAGAGT CTCTCTATTA CATCGAAGAA CTCATCTTTC AACTGCTCAA TAAGCTGTGC 
CTGGCTCAAC CGAGGACTGT TCAAGATGTT GAGGAACGAG TTCAAAAGAC TTTTCCTCAT 
CCTATTGATA AATGGGCAAT TGCTGATGCA CAGTCTGCCA TAGAGAAACG AAAACGAAGA 
AATCCTCTCT TACTACCTGT GGACAAAATC CATCCTTCCT TGAAGGAAGT TTTGGGGTAT 
AAAGTGGACT ACCATGTATC CCTCTACATT GTGGCTGTAT TGGAGTATAT CTCAGCAGAT 
ATTTTGAAAT TGGCTGGTAA TTATGTTTTT AATATCCGGC ATTATGAAAT ATCTCAGCAA 
GACATTAAAG TGTCAATGTG TGCAGATAAG GTTTTGATGG ACATGTTTGA CCAGGATGAC 
GATATAGGCT TGGTTTCTCT CTGTGAAGAG GAACCTTGTT CTTCTGGTGA GCTAAACTAT 
TATGACCTTG TTAGAACTGA AATCGCAGAA GAAAGACAGT ATCTACGGGA ACTGAATATG 
ATCATTAAAG TATTCCGGGA AGCCTTTCTT TCAGACAAAA AGTTGTTCAA GTCTTCTGAA 
ATTGAAAAGA TTTTCAGTAA CATTTCAGAT ATACATGAAC TGACTGTGAA ACTTTTAGGT 
TTGATTGAAG ACACAGTAGA AATGACAGAT GAAAGCAGTC CTCACCCGCT AGCTGGTAGC 
TGCTTTGAAG ATTTAGCAGA GGAGCAGGCT TTTGACCCCT ATGAAACGTT ATCACAGGAC 
ATTCTTGCTC CAGAGTTTAA TGACCACTTC AGCAAGTTGA TGGCCAGACC TGCAGTTGCT 
CTGCACTTTC AGCAGTTGAA AGCATGTAGC GAAGAACAGG AAGACCGAGA GTGTTTGAAT 
CAGGCTATCA CTGCCCTCAT GAACCTCCAA GGCAGCATGG ACCGGATTTA CAAGCAGCAC 
TCGCCAAGGC GCCGGCCAGG GGATCCTGTT TGCCTTTTTT ACAATCGTCA ATTAAGAAGC 
AAGCACCTGG CTATCAAAAA AATGAATGAA ATTCAGAAAA ACATTGATGG GTGGGAAGGC 
AAAGATATTG GACAGTGTTG TAATGAGTTC ATAATGGAAG GACCATTGAC CAGAATTGGT 
GCTAAGCATG AAAGGCATAT TTTCCTCTTC GATGGCTTAA TGATCAGCTG TAAACCCAAT 
CATTGCCAGA CTCGACTTCC AGGGTATAGT AGTGCAGAAT ACAGGTTAAA AGAGAAGTTT 
GTCATGAGGA AAATTCAAAT CTGTGATAAA GAAGACGCTT GTGAATACAA ACATGCTTTT 
GAATTAGTAT CCAAAGATGA AAACAGTGTA ATATTTGCTG CCAAGTCAGC TGAAGAGAAA 
AACAACTGGA TGGCAGCCCT TATCTCCCTT CACTATCGGA GCACTCTAGA TAGAATGCTG 
GACTCTGTGT TACTGAAAGA GGAGAACGAG CAGCCCCTGC GGCTACCGCG GCCAGACGTG 
TACCGCTTCG TGGTGACAGA CTCAGAGGAG AACATAGTTT TTGAAGACAA CTTGCAAAGC 
AGAAGTGGAA TCCCCATTAT TAAAGGAGGC ACCGTGGTGA AACTGATCGA AAGGCTAACA 
TATCACATGT ATGCAGATCC CAATTTTGTT CGTACTTTCC TTACTACGTA TCGTTCATTT 
TGTAAGCCAC AGGAATTGCT AAGCTTGCTG ATAGAACGGT TTGAAATTCC AGATCCAGAG 
CCTACTGAGG CCGACAAACT GGCGCTAGAG AAAGGCGAGC AGCCAATCAG CGCAGATCTG 
AAAAGATTCC GCAAGGAATA TGTCCAACCC GTGCAACTTA GGGTCTTGAA TGTCTTTCGC 
CACTGGGTTG AGCATCATTT TTATGACTTT GAAAGAGACT TGGAATTGCT TGAAAGACTG 
GAAGCCTTCA TTTCAAGTGT AAGAGGGAAA GCCATGAAGA AGTGGGTAGA ATCCATTGCT 
AAAATCATCA AGAGGAAGAA GCAAGCTCAG GCCAATGGAG TAAGCCATAA TATCACCTTT 
GAAAGTCCGC CTCCACCGGT TGAATGGCAC ATAAGTAGGG CGGGACAGTC TGAAACCTTT 
GACCTTATGA CACTTCATCC CATAGAGATT GCACGGCAGT TAACACTCTT GGAATCTGAT 
CTCTACAGGA GAGTCCAGCC TTCTGAACTT GTAGGGAGTG TCTGGACCAA AGAAGATAAA 
GAAATAAATT CTCCAAATCT ATTAAAAATG ATTCGCCATA CAACAAACCT CACTTTGTGG 
TTTGAAAAAT GCATTGTGGA AGCAGAAAAC TTTGAAGAAC GGGTGGCAGT GCTCAGCAGA 
ATAGTAGAAA TTCTGCAAGT GTTTCAAGAT CTGAATAATT TCAATGGCGT GTTGGAGATA 
GTCAGTGCAG TCAATTCAGT GTCAGTGTAC AGACTAGACC ACACATTTGA GGCATTGCAG 
GAAAGGAAGC GGAGAGTTTT GGATGACGCT GTGGAATTAA GTCAGGATCA CTTTAAAAAA 
TACCTAGTAA AACTTAAATC AATCAATCCA CCTTGTGTGC CTTTTTTTGG AATATATTTA 
ACAAATATTC TGAAGACTGA AGAAGGGAAC AGCGACTTTC TAAAGAGGAA AGGGAAAGAT 
TTGATCAATT TCAGTAAGAG GAGAAAAGTG GCTGAAATAA CCGGAGAGAT TCAGCAGTAT 
CAGAACCAAC CATACTGCTT ACGGACAGAA CCAGAGATGA GGAGATTCTT TGAAAACCTC 
AATCCCATGG GACTTTTATC TGAAAAAGAG TTTACAGATT ATTTGTTCAA CAAATCTCAT 
GAAATTGAAC CCCGAAACTG CAAACAACCA CCTCGATTTC CTAGGAAGTC AACCTTTTCC 
TTAAAATCTC CTGGAATAAG GCCCAATGCC AGCCGCCATG GCTCTACCTC AGGCACGTTC 
CGAGGTCACC CAACCCCTCT GGAAAGGGAG CCTTATAAGA TAAGCTTTAG CAGGATCGCC 
GAGACGGAGC TAGAATCCAC GGTGTCAGCA CCGACATCTC CCAACACCCC ATCCACCCCA 
CCTGTGTCTG CTTCTTCAGA CCACAGCGTG TTTCTAGATG TGGACCTCAA TAGCTCCTGT 
GGCAGCAATA CCATCTTTGC TCCAGTCCTC TTGCCACACT CAAAGTCTTT CTTCAGCTCA 
TGTGGAAGTC TACACAAACT GAGTGAAGAG CCACTAGTTC CTCCTCCGCT TCCCCCTCGG 
AAAAAGTTTG ATCACGATGC TCCGAACTCC AAGGGAGCTA TGAAATCGGA TGATGACCCT 
CCTGCTATTC CACCAAGACA ACCCCCTCCT CCAAAGGTAA AGCCAAGAGC TCCTGTCCTC 
ACGGGTACAT TTGAAGGGCC TGTGCCCAGT CCACCTCCAC CTCCTCCCAG AGACCCTCTT 
CCTGATACTC CTCCACCAGT TCCTCTTCGG CCTCCGGAAC ACTTTATAAA CTGTCCGTTT 
AATCTCCAGC CGCCTCCGCT GGGACATCCT CACAGAGACC CAGACTGGCT CAGAGACGTT 
AGCACATGCC CTAATTCACC AAGCACTCCT CCCCCTACGC CCTCGCCACG GATTCCACGC 
AGATGCCATT TGCCCAGCCC CAGTCACAAC AATCTTGCTC ACCCTCCAGC TCCTCCCGTT 
CCACCAAGGC AGAATTCAAG CCCTCACCTA CCAAAACTGC CACCAAAGAC TTACAAGCGG 
GAGCTTTCAC ACCCGCCATT GTACAGACTA CCTTTGTTTG AAAATGCAGA AACTCCTCAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008762943.1
CDS	143..4045
Translation	MQQAPQPYEFFSEENSPKWRGLLVPALRKVQEQVHPTLSANEESLYYIEELIFQLLNKLCLAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGYKVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDDDIGLVSLCEEEPCSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDKKLFKSSEIEKIFSNISDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDILAPEFNDHFSKLMARPAVALHFQQLKACSEEQEDRECLNQAITALMNLQGSMDRIYKQHSPRRRPGDPVCLFYNRQLRSKHLAIKKMNEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKPNHCQTRLPGYSSAEYRLKEKFVMRKIQICDKEDACEYKHAFELVSKDENSVIFAAKSAEEKNNWMAALISLHYRSTLDRMLDSVLLKEENEQPLRLPRPDVYRFVVTDSEENIVFEDNLQSRSGIPIIKGGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPDPEPTEADKLALEKGEQPISADLKRFRKEYVQPVQLRVLNVFRHWVEHHFYDFERDLELLERLEAFISSVRGKAMKKWVESIAKIIKRKKQAQANGVSHNITFESPPPPVEWHISRAGQSETFDLMTLHPIEIARQLTLLESDLYRRVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEAENFEERVAVLSRIVEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRRVLDDAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNSDFLKRKGKDLINFSKRRKVAEITGEIQQYQNQPYCLRTEPEMRRFFENLNPMGLLSEKEFTDYLFNKSHEIEPRNCKQPPRFPRKSTFSLKSPGIRPNASRHGSTSGTFRGHPTPLEREPYKISFSRIAETELESTVSAPTSPNTPSTPPVSASSDHSVFLDVDLNSSCGSNTIFAPVLLPHSKSFFSSCGSLHKLSEEPLVPPPLPPRKKFDHDAPNSKGAMKSDDDPPAIPPRQPPPPKVKPRAPVLTGTFEGPVPSPPPPPPRDPLPDTPPPVPLRPPEHFINCPFNLQPPPLGHPHRDPDWLRDVSTCPNSPSTPPPTPSPRIPRRCHLPSPSHNNLAHPPAPPVPPRQNSSPHLPKLPPKTYKRELSHPPLYRLPLFENAETPQ

Target ORF information:

RefSeq Version	XM_008764721.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus SOS Ras/Rho guanine nucleotide exchange factor 2 (Sos2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008764721.1

ORF Insert Sequence:

ATGCAGCAGG CGCCGCAGCC CTACGAGTTC TTCAGCGAAG AGAACAGCCC GAAATGGCGG 
GGACTGTTGG TCCCGGCCCT GCGGAAGGTT CAGGAGCAAG TGCACCCCAC CCTGTCGGCT 
AACGAAGAGT CTCTCTATTA CATCGAAGAA CTCATCTTTC AACTGCTCAA TAAGCTGTGC 
CTGGCTCAAC CGAGGACTGT TCAAGATGTT GAGGAACGAG TTCAAAAGAC TTTTCCTCAT 
CCTATTGATA AATGGGCAAT TGCTGATGCA CAGTCTGCCA TAGAGAAACG AAAACGAAGA 
AATCCTCTCT TACTACCTGT GGACAAAATC CATCCTTCCT TGAAGGAAGT TTTGGGGTAT 
AAAGTGGACT ACCATGTATC CCTCTACATT GTGGCTGTAT TGGAGTATAT CTCAGCAGAT 
ATTTTGAAAT TGGCTGGTAA TTATGTTTTT AATATCCGGC ATTATGAAAT ATCTCAGCAA 
GACATTAAAG TGTCAATGTG TGCAGATAAG GTTTTGATGG ACATGTTTGA CCAGGATGAC 
GATATAGGCT TGGTTTCTCT CTGTGAAGAG GAACCTTGTT CTTCTGGTGA GCTAAACTAT 
TATGACCTTG TTAGAACTGA AATCGCAGAA GAAAGACAGT ATCTACGGGA ACTGAATATG 
ATCATTAAAG TATTCCGGGA AGCCTTTCTT TCAGACAAAA AGTTGTTCAA GTCTTCTGAA 
ATTGAAAAGA TTTTCAGTAA CATTTCAGAT ATACATGAAC TGACTGTGAA ACTTTTAGGT 
TTGATTGAAG ACACAGTAGA AATGACAGAT GAAAGCAGTC CTCACCCGCT AGCTGGTAGC 
TGCTTTGAAG ATTTAGCAGA GGAGCAGGCT TTTGACCCCT ATGAAACGTT ATCACAGGAC 
ATTCTTGCTC CAGAGTTTAA TGACCACTTC AGCAAGTTGA TGGCCAGACC TGCAGTTGCT 
CTGCACTTTC AGCAGTTGAA AGCATGTAGC GAAGAACAGG AAGACCGAGA GTGTTTGAAT 
CAGGCTATCA CTGCCCTCAT GAACCTCCAA GGCAGCATGG ACCGGATTTA CAAGCAGCAC 
TCGCCAAGGC GCCGGCCAGG GGATCCTGTT TGCCTTTTTT ACAATCGTCA ATTAAGAAGC 
AAGCACCTGG CTATCAAAAA AATGAATGAA ATTCAGAAAA ACATTGATGG GTGGGAAGGC 
AAAGATATTG GACAGTGTTG TAATGAGTTC ATAATGGAAG GACCATTGAC CAGAATTGGT 
GCTAAGCATG AAAGGCATAT TTTCCTCTTC GATGGCTTAA TGATCAGCTG TAAACCCAAT 
CATTGCCAGA CTCGACTTCC AGGGTATAGT AGTGCAGAAT ACAGGTTAAA AGAGAAGTTT 
GTCATGAGGA AAATTCAAAT CTGTGATAAA GAAGACGCTT GTGAATACAA ACATGCTTTT 
GAATTAGTAT CCAAAGATGA AAACAGTGTA ATATTTGCTG CCAAGTCAGC TGAAGAGAAA 
AACAACTGGA TGGCAGCCCT TATCTCCCTT CACTATCGGA GCACTCTAGA TAGAATGCTG 
GACTCTGTGT TACTGAAAGA GGAGAACGAG CAGCCCCTGC GGCTACCGCG GCCAGACGTG 
TACCGCTTCG TGGTGACAGA CTCAGAGGAG AACATAGTTT TTGAAGACAA CTTGCAAAGC 
AGAAGTGGAA TCCCCATTAT TAAAGGAGGC ACCGTGGTGA AACTGATCGA AAGGCTAACA 
TATCACATGT ATGCAGATCC CAATTTTGTT CGTACTTTCC TTACTACGTA TCGTTCATTT 
TGTAAGCCAC AGGAATTGCT AAGCTTGCTG ATAGAACGGT TTGAAATTCC AGATCCAGAG 
CCTACTGAGG CCGACAAACT GGCGCTAGAG AAAGGCGAGC AGCCAATCAG CGCAGATCTG 
AAAAGATTCC GCAAGGAATA TGTCCAACCC GTGCAACTTA GGGTCTTGAA TGTCTTTCGC 
CACTGGGTTG AGCATCATTT TTATGACTTT GAAAGAGACT TGGAATTGCT TGAAAGACTG 
GAAGCCTTCA TTTCAAGTGT AAGAGGGAAA GCCATGAAGA AGTGGGTAGA ATCCATTGCT 
AAAATCATCA AGAGGAAGAA GCAAGCTCAG GCCAATGGAG TAAGCCATAA TATCACCTTT 
GAAAGTCCGC CTCCACCGGT TGAATGGCAC ATAAGTAGGG CGGGACAGTC TGAAACCTTT 
GACCTTATGA CACTTCATCC CATAGAGATT GCACGGCAGT TAACACTCTT GGAATCTGAT 
CTCTACAGGA GAGTCCAGCC TTCTGAACTT GTAGGGAGTG TCTGGACCAA AGAAGATAAA 
GAAATAAATT CTCCAAATCT ATTAAAAATG ATTCGCCATA CAACAAACCT CACTTTGTGG 
TTTGAAAAAT GCATTGTGGA AGCAGAAAAC TTTGAAGAAC GGGTGGCAGT GCTCAGCAGA 
ATAGTAGAAA TTCTGCAAGT GTTTCAAGAT CTGAATAATT TCAATGGCGT GTTGGAGATA 
GTCAGTGCAG TCAATTCAGT GTCAGTGTAC AGACTAGACC ACACATTTGA GGCATTGCAG 
GAAAGGAAGC GGAGAGTTTT GGATGACGCT GTGGAATTAA GTCAGGATCA CTTTAAAAAA 
TACCTAGTAA AACTTAAATC AATCAATCCA CCTTGTGTGC CTTTTTTTGG AATATATTTA 
ACAAATATTC TGAAGACTGA AGAAGGGAAC AGCGACTTTC TAAAGAGGAA AGGGAAAGAT 
TTGATCAATT TCAGTAAGAG GAGAAAAGTG GCTGAAATAA CCGGAGAGAT TCAGCAGTAT 
CAGAACCAAC CATACTGCTT ACGGACAGAA CCAGAGATGA GGAGATTCTT TGAAAACCTC 
AATCCCATGG GACTTTTATC TGAAAAAGAG TTTACAGATT ATTTGTTCAA CAAATCTCAT 
GAAATTGAAC CCCGAAACTG CAAACAACCA CCTCGATTTC CTAGGAAGTC AACCTTTTCC 
TTAAAATCTC CTGGAATAAG GCCCAATGCC AGCCGCCATG GCTCTACCTC AGGCACGTTC 
CGAGGTCACC CAACCCCTCT GGAAAGGGAG CCTTATAAGA TAAGCTTTAG CAGGATCGCC 
GAGACGGAGC TAGAATCCAC GGTGTCAGCA CCGACATCTC CCAACACCCC ATCCACCCCA 
CCTGTGTCTG CTTCTTCAGA CCACAGCGTG TTTCTAGATG TGGACCTCAA TAGCTCCTGT 
GGCAGCAATA CCATCTTTGC TCCAGTCCTC TTGCCACACT CAAAGTCTTT CTTCAGCTCA 
TGTGGAAGTC TACACAAACT GAGTGAAGAG CCACTAGTTC CTCCTCCGCT TCCCCCTCGG 
AAAAAGTTTG ATCACGATGC TCCGAACTCC AAGGGAGCTA TGAAATCGGA TGATGACCCT 
CCTGCTATTC CACCAAGACA ACCCCCTCCT CCAAAGGTAA AGCCAAGAGC TCCTGTCCTC 
ACGGGTACAT TTGAAGGGCC TGTGCCCAGT CCACCTCCAC CTCCTCCCAG AGACCCTCTT 
CCTGATACTC CTCCACCAGT TCCTCTTCGG CCTCCGGAAC ACTTTATAAA CTGTCCGTTT 
AATCTCCAGC CGCCTCCGCT GGGACATCCT CACAGAGACC CAGACTGGCT CAGAGACGTT 
AGCACATGCC CTAATTCACC AAGCACTCCT CCCCCTACGC CCTCGCCACG GATTCCACGC 
AGATGCCATT TGCCCAGCCC CAGTCACAAC AATCTTGCTC ACCCTCCAGC TCCTCCCGTT 
CCACCAAGGC AGAATTCAAG CCCTCACCTA CCAAAACTGC CACCAAAGAC TTACAAGCGG 
GAGCTTTCAC ACCCGCCATT GTACAGACTA CCTTTGTTTG AAAATGCAGA AACTCCTCAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Sos2 ( NM_001135561.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001129033.1 Rattus norvegicus SOS Ras/Rho guanine nucleotide exchange factor 2 (Sos2), mRNA.

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CloneID	ORa12010
Clone ID Related Accession (Same CDS sequence)	NM_001135561.1
Accession Version	NM_001135561.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4002bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Rattus norvegicus(Norway rat)
Product	son of sevenless homolog 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07064731.1, AABR07064728.1 and AABR07064727.1. On Oct 1, 2008 this sequence version replaced XM_001080400.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGCAGCAGG CGCCGCAGCC CTACGAGTTC TTCAGCGAAG AGAACAGCCC GAAATGGCGG 
GGACTGTTGG TCCCGGCCCT GCGGAAGGTT CAGGAGCAAG TGCACCCCAC CCTGTCGGCT 
AACGAAGAGT CTCTCTATTA CATCGAAGAA CTCATCTTTC AACTGCTCAA TAAGCTGTGC 
CTGGCTCAAC CGAGGACTGT TCAAGATGTT GAGGAACGAG TTCAAAAGAC TTTTCCTCAT 
CCTATTGATA AATGGGCAAT TGCTGATGCA CAGTCTGCCA TAGAGAAACG AAAACGAAGA 
AATCCTCTCT TACTACCTGT GGACAAAATC CATCCTTCCT TGAAGGAAGT TTTGGGGTAT 
AAAGTGGACT ACCATGTATC CCTCTACATT GTGGCTGTAT TGGAGTATAT CTCAGCAGAT 
ATTTTGAAAT TGGCTGGTAA TTATGTTTTT AATATCCGGC ATTATGAAAT ATCTCAGCAA 
GACATTAAAG TGTCAATGTG TGCAGATAAG GTTTTGATGG ACATGTTTGA CCAGGATGAC 
GATATAGGCT TGGTTTCTCT CTGTGAAGAG GAACCTTGTT CTTCTGGTGA GCTAAACTAT 
TATGACCTTG TTAGAACTGA AATCGCAGAA GAAAGACAGT ATCTACGGGA ACTGAATATG 
ATCATTAAAG TATTCCGGGA AGCCTTTCTT TCAGACAAAA AGTTGTTCAA GTCTTCTGAA 
ATTGAAAAGA TTTTCAGTAA CATTTCAGAT ATACATGAAC TGACTGTGAA ACTTTTAGGT 
TTGATTGAAG ACACAGTAGA AATGACAGAT GAAAGCAGTC CTCACCCGCT AGCTGGTAGC 
TGCTTTGAAG ATTTAGCAGA GGAGCAGGCT TTTGACCCCT ATGAAACGTT ATCACAGGAC 
ATTCTTGCTC CAGAGTTTAA TGACCACTTC AGCAAGTTGA TGGCCAGACC TGCAGTTGCT 
CTGCACTTTC AGTCCATTGC TGACGGCTTT AAGGAGGCTG TTCGATATGT CCTTCCGCGC 
CTCATGCTGG TGCCGGTGTA TCATTGTTGG CATTACTTTG AATTATTAAA GCAGTTGAAA 
GCATGTAGCG AAGAACAGGA AGACCGAGAG TGTTTGAATC AGGCTATCAC TGCCCTCATG 
AACCTCCAAG GCAGCATGGA CCGGATTTAC AAGCAGCACT CGCCAAGGCG CCGGCCAGGG 
GATCCTGTTT GCCTTTTTTA CAATCGTCAA TTAAGAAGCA AGCACCTGGC TATCAAAAAA 
ATGAATGAAA TTCAGAAAAA CATTGATGGG TGGGAAGGCA AAGATATTGG ACAGTGTTGT 
AATGAGTTCA TAATGGAAGG ACCATTGACC AGAATTGGTG CTAAGCATGA AAGGCATATT 
TTCCTCTTCG ATGGCTTAAT GATCAGCTGT AAACCCAATC ATTGCCAGAC TCGACTTCCA 
GGGTATAGTA GTGCAGAATA CAGGTTAAAA GAGAAGTTTG TCATGAGGAA AATTCAAATC 
TGTGATAAAG AAGACGCTTG TGAATACAAA CATGCTTTTG AATTAGTATC CAAAGATGAA 
AACAGTGTAA TATTTGCTGC CAAGTCAGCT GAAGAGAAAA ACAACTGGAT GGCAGCCCTT 
ATCTCCCTTC ACTATCGGAG CACTCTAGAT AGAATGCTGG ACTCTGTGTT ACTGAAAGAG 
GAGAACGAGC AGCCCCTGCG GCTACCGCGG CCAGACGTGT ACCGCTTCGT GGTGACAGAC 
TCAGAGGAGA ACATAGTTTT TGAAGACAAC TTGCAAAGCA GAAGTGGAAT CCCCATTATT 
AAAGGAGGCA CCGTGGTGAA ACTGATCGAA AGGCTAACAT ATCACATGTA TGCAGATCCC 
AATTTTGTTC GTACTTTCCT TACTACGTAT CGTTCATTTT GTAAGCCACA GGAATTGCTA 
AGCTTGCTGA TAGAACGGTT TGAAATTCCA GATCCAGAGC CTACTGAGGC CGACAAACTG 
GCGCTAGAGA AAGGCGAGCA GCCAATCAGC GCAGATCTGA AAAGATTCCG CAAGGAATAT 
GTCCAACCCG TGCAACTTAG GGTCTTGAAT GTCTTTCGCC ACTGGGTTGA GCATCATTTT 
TATGACTTTG AAAGAGACTT GGAATTGCTT GAAAGACTGG AAGCCTTCAT TTCAAGTGTA 
AGAGGGAAAG CCATGAAGAA GTGGGTAGAA TCCATTGCTA AAATCATCAA GAGGAAGAAG 
CAAGCTCAGG CCAATGGAGT AAGCCATAAT ATCACCTTTG AAAGTCCGCC TCCACCGGTT 
GAATGGCACA TAAGTAGGGC GGGACAGTCT GAAACCTTTG ACCTTATGAC ACTTCATCCC 
ATAGAGATTG CACGGCAGTT AACACTCTTG GAATCTGATC TCTACAGGAG AGTCCAGCCT 
TCTGAACTTG TAGGGAGTGT CTGGACCAAA GAAGATAAAG AAATAAATTC TCCAAATCTA 
TTAAAAATGA TTCGCCATAC AACAAACCTC ACTTTGTGGT TTGAAAAATG CATTGTGGAA 
GCAGAAAACT TTGAAGAACG GGTGGCAGTG CTCAGCAGAA TAGTAGAAAT TCTGCAAGTG 
TTTCAAGATC TGAATAATTT CAATGGCGTG TTGGAGATAG TCAGTGCAGT CAATTCAGTG 
TCAGTGTACA GACTAGACCA CACATTTGAG GCATTGCAGG AAAGGAAGCG GAGAGTTTTG 
GATGACGCTG TGGAATTAAG TCAGGATCAC TTTAAAAAAT ACCTAGTAAA ACTTAAATCA 
ATCAATCCAC CTTGTGTGCC TTTTTTTGGA ATATATTTAA CAAATATTCT GAAGACTGAA 
GAAGGGAACA GCGACTTTCT AAAGAGGAAA GGGAAAGATT TGATCAATTT CAGTAAGAGG 
AGAAAAGTGG CTGAAATAAC CGGAGAGATT CAGCAGTATC AGAACCAACC ATACTGCTTA 
CGGACAGAAC CAGAGATGAG GAGATTCTTT GAAAACCTCA ATCCCATGGG ACTTTTATCT 
GAAAAAGAGT TTACAGATTA TTTGTTCAAC AAATCTCATG AAATTGAACC CCGAAACTGC 
AAACAACCAC CTCGATTTCC TAGGAAGTCA ACCTTTTCCT TAAAATCTCC TGGAATAAGG 
CCCAATGCCA GCCGCCATGG CTCTACCTCA GGCACGTTCC GAGGTCACCC AACCCCTCTG 
GAAAGGGAGC CTTATAAGAT AAGCTTTAGC AGGATCGCCG AGACGGAGCT AGAATCCACG 
GTGTCAGCAC CGACATCTCC CAACACCCCA TCCACCCCAC CTGTGTCTGC TTCTTCAGAC 
CACAGCGTGT TTCTAGATGT GGACCTCAAT AGCTCCTGTG GCAGCAATAC CATCTTTGCT 
CCAGTCCTCT TGCCACACTC AAAGTCTTTC TTCAGCTCAT GTGGAAGTCT ACACAAACTG 
AGTGAAGAGC CACTAGTTCC TCCTCCGCTT CCCCCTCGGA AAAAGTTTGA TCACGATGCT 
CCGAACTCCA AGGGAGCTAT GAAATCGGAT GATGACCCTC CTGCTATTCC ACCAAGACAA 
CCCCCTCCTC CAAAGGTAAA GCCAAGAGCT CCTGTCCTCA CGGGTACATT TGAAGGGCCT 
GTGCCCAGTC CACCTCCACC TCCTCCCAGA GACCCTCTTC CTGATACTCC TCCACCAGTT 
CCTCTTCGGC CTCCGGAACA CTTTATAAAC TGTCCGTTTA ATCTCCAGCC GCCTCCGCTG 
GGACATCCTC ACAGAGACCC AGACTGGCTC AGAGACGTTA GCACATGCCC TAATTCACCA 
AGCACTCCTC CCCCTACGCC CTCGCCACGG ATTCCACGCA GATGCCATTT GCCCAGCCCC 
AGTCACAACA ATCTTGCTCA CCCTCCAGCT CCTCCCGTTC CACCAAGGCA GAATTCAAGC 
CCTCACCTAC CAAAACTGCC ACCAAAGACT TACAAGCGGG AGCTTTCACA CCCGCCATTG 
TACAGACTAC CTTTGTTTGA AAATGCAGAA ACTCCTCAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001129033.1
CDS	1..4002
Translation	MQQAPQPYEFFSEENSPKWRGLLVPALRKVQEQVHPTLSANEESLYYIEELIFQLLNKLCLAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGYKVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDDDIGLVSLCEEEPCSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDKKLFKSSEIEKIFSNISDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDILAPEFNDHFSKLMARPAVALHFQSIADGFKEAVRYVLPRLMLVPVYHCWHYFELLKQLKACSEEQEDRECLNQAITALMNLQGSMDRIYKQHSPRRRPGDPVCLFYNRQLRSKHLAIKKMNEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKPNHCQTRLPGYSSAEYRLKEKFVMRKIQICDKEDACEYKHAFELVSKDENSVIFAAKSAEEKNNWMAALISLHYRSTLDRMLDSVLLKEENEQPLRLPRPDVYRFVVTDSEENIVFEDNLQSRSGIPIIKGGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPDPEPTEADKLALEKGEQPISADLKRFRKEYVQPVQLRVLNVFRHWVEHHFYDFERDLELLERLEAFISSVRGKAMKKWVESIAKIIKRKKQAQANGVSHNITFESPPPPVEWHISRAGQSETFDLMTLHPIEIARQLTLLESDLYRRVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEAENFEERVAVLSRIVEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRRVLDDAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNSDFLKRKGKDLINFSKRRKVAEITGEIQQYQNQPYCLRTEPEMRRFFENLNPMGLLSEKEFTDYLFNKSHEIEPRNCKQPPRFPRKSTFSLKSPGIRPNASRHGSTSGTFRGHPTPLEREPYKISFSRIAETELESTVSAPTSPNTPSTPPVSASSDHSVFLDVDLNSSCGSNTIFAPVLLPHSKSFFSSCGSLHKLSEEPLVPPPLPPRKKFDHDAPNSKGAMKSDDDPPAIPPRQPPPPKVKPRAPVLTGTFEGPVPSPPPPPPRDPLPDTPPPVPLRPPEHFINCPFNLQPPPLGHPHRDPDWLRDVSTCPNSPSTPPPTPSPRIPRRCHLPSPSHNNLAHPPAPPVPPRQNSSPHLPKLPPKTYKRELSHPPLYRLPLFENAETPQ

Target ORF information:

RefSeq Version	NM_001135561.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus SOS Ras/Rho guanine nucleotide exchange factor 2 (Sos2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001135561.1

ORF Insert Sequence:

ATGCAGCAGG CGCCGCAGCC CTACGAGTTC TTCAGCGAAG AGAACAGCCC GAAATGGCGG 
GGACTGTTGG TCCCGGCCCT GCGGAAGGTT CAGGAGCAAG TGCACCCCAC CCTGTCGGCT 
AACGAAGAGT CTCTCTATTA CATCGAAGAA CTCATCTTTC AACTGCTCAA TAAGCTGTGC 
CTGGCTCAAC CGAGGACTGT TCAAGATGTT GAGGAACGAG TTCAAAAGAC TTTTCCTCAT 
CCTATTGATA AATGGGCAAT TGCTGATGCA CAGTCTGCCA TAGAGAAACG AAAACGAAGA 
AATCCTCTCT TACTACCTGT GGACAAAATC CATCCTTCCT TGAAGGAAGT TTTGGGGTAT 
AAAGTGGACT ACCATGTATC CCTCTACATT GTGGCTGTAT TGGAGTATAT CTCAGCAGAT 
ATTTTGAAAT TGGCTGGTAA TTATGTTTTT AATATCCGGC ATTATGAAAT ATCTCAGCAA 
GACATTAAAG TGTCAATGTG TGCAGATAAG GTTTTGATGG ACATGTTTGA CCAGGATGAC 
GATATAGGCT TGGTTTCTCT CTGTGAAGAG GAACCTTGTT CTTCTGGTGA GCTAAACTAT 
TATGACCTTG TTAGAACTGA AATCGCAGAA GAAAGACAGT ATCTACGGGA ACTGAATATG 
ATCATTAAAG TATTCCGGGA AGCCTTTCTT TCAGACAAAA AGTTGTTCAA GTCTTCTGAA 
ATTGAAAAGA TTTTCAGTAA CATTTCAGAT ATACATGAAC TGACTGTGAA ACTTTTAGGT 
TTGATTGAAG ACACAGTAGA AATGACAGAT GAAAGCAGTC CTCACCCGCT AGCTGGTAGC 
TGCTTTGAAG ATTTAGCAGA GGAGCAGGCT TTTGACCCCT ATGAAACGTT ATCACAGGAC 
ATTCTTGCTC CAGAGTTTAA TGACCACTTC AGCAAGTTGA TGGCCAGACC TGCAGTTGCT 
CTGCACTTTC AGTCCATTGC TGACGGCTTT AAGGAGGCTG TTCGATATGT CCTTCCGCGC 
CTCATGCTGG TGCCGGTGTA TCATTGTTGG CATTACTTTG AATTATTAAA GCAGTTGAAA 
GCATGTAGCG AAGAACAGGA AGACCGAGAG TGTTTGAATC AGGCTATCAC TGCCCTCATG 
AACCTCCAAG GCAGCATGGA CCGGATTTAC AAGCAGCACT CGCCAAGGCG CCGGCCAGGG 
GATCCTGTTT GCCTTTTTTA CAATCGTCAA TTAAGAAGCA AGCACCTGGC TATCAAAAAA 
ATGAATGAAA TTCAGAAAAA CATTGATGGG TGGGAAGGCA AAGATATTGG ACAGTGTTGT 
AATGAGTTCA TAATGGAAGG ACCATTGACC AGAATTGGTG CTAAGCATGA AAGGCATATT 
TTCCTCTTCG ATGGCTTAAT GATCAGCTGT AAACCCAATC ATTGCCAGAC TCGACTTCCA 
GGGTATAGTA GTGCAGAATA CAGGTTAAAA GAGAAGTTTG TCATGAGGAA AATTCAAATC 
TGTGATAAAG AAGACGCTTG TGAATACAAA CATGCTTTTG AATTAGTATC CAAAGATGAA 
AACAGTGTAA TATTTGCTGC CAAGTCAGCT GAAGAGAAAA ACAACTGGAT GGCAGCCCTT 
ATCTCCCTTC ACTATCGGAG CACTCTAGAT AGAATGCTGG ACTCTGTGTT ACTGAAAGAG 
GAGAACGAGC AGCCCCTGCG GCTACCGCGG CCAGACGTGT ACCGCTTCGT GGTGACAGAC 
TCAGAGGAGA ACATAGTTTT TGAAGACAAC TTGCAAAGCA GAAGTGGAAT CCCCATTATT 
AAAGGAGGCA CCGTGGTGAA ACTGATCGAA AGGCTAACAT ATCACATGTA TGCAGATCCC 
AATTTTGTTC GTACTTTCCT TACTACGTAT CGTTCATTTT GTAAGCCACA GGAATTGCTA 
AGCTTGCTGA TAGAACGGTT TGAAATTCCA GATCCAGAGC CTACTGAGGC CGACAAACTG 
GCGCTAGAGA AAGGCGAGCA GCCAATCAGC GCAGATCTGA AAAGATTCCG CAAGGAATAT 
GTCCAACCCG TGCAACTTAG GGTCTTGAAT GTCTTTCGCC ACTGGGTTGA GCATCATTTT 
TATGACTTTG AAAGAGACTT GGAATTGCTT GAAAGACTGG AAGCCTTCAT TTCAAGTGTA 
AGAGGGAAAG CCATGAAGAA GTGGGTAGAA TCCATTGCTA AAATCATCAA GAGGAAGAAG 
CAAGCTCAGG CCAATGGAGT AAGCCATAAT ATCACCTTTG AAAGTCCGCC TCCACCGGTT 
GAATGGCACA TAAGTAGGGC GGGACAGTCT GAAACCTTTG ACCTTATGAC ACTTCATCCC 
ATAGAGATTG CACGGCAGTT AACACTCTTG GAATCTGATC TCTACAGGAG AGTCCAGCCT 
TCTGAACTTG TAGGGAGTGT CTGGACCAAA GAAGATAAAG AAATAAATTC TCCAAATCTA 
TTAAAAATGA TTCGCCATAC AACAAACCTC ACTTTGTGGT TTGAAAAATG CATTGTGGAA 
GCAGAAAACT TTGAAGAACG GGTGGCAGTG CTCAGCAGAA TAGTAGAAAT TCTGCAAGTG 
TTTCAAGATC TGAATAATTT CAATGGCGTG TTGGAGATAG TCAGTGCAGT CAATTCAGTG 
TCAGTGTACA GACTAGACCA CACATTTGAG GCATTGCAGG AAAGGAAGCG GAGAGTTTTG 
GATGACGCTG TGGAATTAAG TCAGGATCAC TTTAAAAAAT ACCTAGTAAA ACTTAAATCA 
ATCAATCCAC CTTGTGTGCC TTTTTTTGGA ATATATTTAA CAAATATTCT GAAGACTGAA 
GAAGGGAACA GCGACTTTCT AAAGAGGAAA GGGAAAGATT TGATCAATTT CAGTAAGAGG 
AGAAAAGTGG CTGAAATAAC CGGAGAGATT CAGCAGTATC AGAACCAACC ATACTGCTTA 
CGGACAGAAC CAGAGATGAG GAGATTCTTT GAAAACCTCA ATCCCATGGG ACTTTTATCT 
GAAAAAGAGT TTACAGATTA TTTGTTCAAC AAATCTCATG AAATTGAACC CCGAAACTGC 
AAACAACCAC CTCGATTTCC TAGGAAGTCA ACCTTTTCCT TAAAATCTCC TGGAATAAGG 
CCCAATGCCA GCCGCCATGG CTCTACCTCA GGCACGTTCC GAGGTCACCC AACCCCTCTG 
GAAAGGGAGC CTTATAAGAT AAGCTTTAGC AGGATCGCCG AGACGGAGCT AGAATCCACG 
GTGTCAGCAC CGACATCTCC CAACACCCCA TCCACCCCAC CTGTGTCTGC TTCTTCAGAC 
CACAGCGTGT TTCTAGATGT GGACCTCAAT AGCTCCTGTG GCAGCAATAC CATCTTTGCT 
CCAGTCCTCT TGCCACACTC AAAGTCTTTC TTCAGCTCAT GTGGAAGTCT ACACAAACTG 
AGTGAAGAGC CACTAGTTCC TCCTCCGCTT CCCCCTCGGA AAAAGTTTGA TCACGATGCT 
CCGAACTCCA AGGGAGCTAT GAAATCGGAT GATGACCCTC CTGCTATTCC ACCAAGACAA 
CCCCCTCCTC CAAAGGTAAA GCCAAGAGCT CCTGTCCTCA CGGGTACATT TGAAGGGCCT 
GTGCCCAGTC CACCTCCACC TCCTCCCAGA GACCCTCTTC CTGATACTCC TCCACCAGTT 
CCTCTTCGGC CTCCGGAACA CTTTATAAAC TGTCCGTTTA ATCTCCAGCC GCCTCCGCTG 
GGACATCCTC ACAGAGACCC AGACTGGCTC AGAGACGTTA GCACATGCCC TAATTCACCA 
AGCACTCCTC CCCCTACGCC CTCGCCACGG ATTCCACGCA GATGCCATTT GCCCAGCCCC 
AGTCACAACA ATCTTGCTCA CCCTCCAGCT CCTCCCGTTC CACCAAGGCA GAATTCAAGC 
CCTCACCTAC CAAAACTGCC ACCAAAGACT TACAAGCGGG AGCTTTCACA CCCGCCATTG 
TACAGACTAC CTTTGTTTGA AAATGCAGAA ACTCCTCAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Functional redundancy of Sos1 and Sos2 for lymphopoiesis and organismal homeostasis and survival.
Molecular and cellular biology33(22)4562-78(2013 Nov)
Baltan?s FC,P?rez-Andr?s M,Ginel-Picardo A,Diaz D,Jimeno D,Liceras-Boillos P,Kortum RL,Samelson LE,Orfao A,Santos E

IL-6/IL-6 receptor system and its role in physiological and pathological conditions.
Clinical science (London, England : 1979)122(4)143-59(2012 Feb)
Mihara M,Hashizume M,Yoshida H,Suzuki M,Shiina M

Src-dependent TrkA transactivation is required for pituitary adenylate cyclase-activating polypeptide 38-mediated Rit activation and neuronal differentiation.
Molecular biology of the cell21(9)1597-608(2010 May)
Shi GX,Jin L,Andres DA

EGF-ERBB signalling: towards the systems level.
Nature reviews. Molecular cell biology7(7)505-16(2006 Jul)
Citri A,Yarden Y

Local phosphatidylinositol 3,4,5-trisphosphate accumulation recruits Vav2 and Vav3 to activate Rac1/Cdc42 and initiate neurite outgrowth in nerve growth factor-stimulated PC12 cells.
Molecular biology of the cell16(5)2207-17(2005 May)
Aoki K,Nakamura T,Fujikawa K,Matsuda M