Synj1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Synj1
Entrez Gene ID	85238
Full Name	synaptojanin 1
General protein information	Preferred Names synaptojanin 1 Names synaptojanin-1 synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 11 Map Location: 11q11
Summary	has inositol 5-phosphatase activity; interacts with dynamin to play a role in synaptic vesicle recycling [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_053476.2	NP_445928.2	synaptojanin-1

Pathways from BioSystems

Homologies

Homo sapiens (human)	SYNJ1	NP_003886.3
Pan troglodytes (chimpanzee)	SYNJ1	XP_531429.2
Gallus gallus (chicken)	SYNJ1	XP_416706.3
Xenopus tropicalis (tropical clawed frog)	synj1	XP_004912203.1
Canis lupus familiaris (dog)	SYNJ1	XP_005638893.1
Caenorhabditis elegans (roundworm)	unc-26	NP_001023266.1
Rattus norvegicus (Norway rat)	Synj1	NP_445928.2
Danio rerio (zebrafish)	synj1	NP_001007031.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012175	XP_320360.4
Caenorhabditis elegans (roundworm)	unc-26	NP_001129862.1
	SYNJ1	XP_002803210.1
Bos taurus (cattle)	SYNJ1	NP_776893.2
Mus musculus (house mouse)	Synj1	NP_001157955.1
Drosophila melanogaster (fruit fly)	synj	NP_001246454.1

Gene Ontology
Bibliography

Related articles in PubMed

Impaired intracellular trafficking defines early Parkinson's disease.
Hunn BH, Cragg SJ, Bolam JP, Spillantini MG, Wade-Martins R
Trends in neurosciences38(3)178-88(2015 Mar)

Synaptojanin 1 mutation in Parkinson's disease brings further insight into the neuropathological mechanisms.
Drouet V, Lesage S
BioMed research international2014289728(2014)

Synaptic vesicle endocytosis.
Saheki Y, De Camilli P
Cold Spring Harbor perspectives in biology4(9)a005645(2012 Sep)

Trisomy for synaptojanin1 in Down syndrome is functionally linked to the enlargement of early endosomes.
Cossec JC, Lavaur J, Berman DE, Rivals I, Hoischen A, Stora S, Ripoll C, Mircher C, Grattau Y, Olivomarin JC, de Chaumont F, Lecourtois M, Antonarakis SE, Veltman JA, Delabar JM, Duyckaerts C, Di Paolo G, Potier MC
Human molecular genetics21(14)3156-72(2012 Jul)

Recruitment of endophilin to clathrin-coated pit necks is required for efficient vesicle uncoating after fission.
Milosevic I, Giovedi S, Lou X, Raimondi A, Collesi C, Shen H, Paradise S, O'Toole E, Ferguson S, Cremona O, De Camilli P
Neuron72(4)587-601(2011 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Two proteins with prominent functions in endocytosis, synaptojanin-1 and dynamin, bind to the SH3 domain of human Myo1E.
Title: Myosin 1E interacts with synaptojanin-1 and dynamin and is involved in endocytosis.

EphrinB-EphB signalling regulates clathrin-mediated endocytosis in various cellular contexts by influencing protein interactions and phosphoinositide turnover through tyrosine phosphorylation of synaptojanin 1.
Title: EphrinB-EphB signalling regulates clathrin-mediated endocytosis through tyrosine phosphorylation of synaptojanin 1.

concentrated in presynaptic nerve terminals, where it dephosphorylates a pool of phosphatidylinositol
Title: Regulation of synaptojanin 1 by cyclin-dependent kinase 5 at synapses.

characterization and purification from rat brain
Title: Characterization and purification of phosphatidylinositol trisphosphate 5-phosphatase from rat brain tissues.

The following Synj1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Synj1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa09646	NM_053476.2 Latest version!	Rattus norvegicus synaptojanin 1 (Synj1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$643.30 $919.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Synj1 ( NM_053476.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_445928.2 Rattus norvegicus synaptojanin 1 (Synj1), mRNA.

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CloneID	ORa09646
Clone ID Related Accession (Same CDS sequence)	NM_053476.2
Accession Version	NM_053476.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3879bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-22
Organism	Rattus norvegicus(Norway rat)
Product	synaptojanin-1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U45479.2. On or before Oct 23, 2008 this sequence version replaced XM_573256.2, XM_001073290.1, NM_053476.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U45479.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGCGTTCA GCAAAGGATT TCGAATCTAC CACAAATTGG ATCCCCCACC GTTCAGCCTC 
ATAGTGGAAA CTAGGCATAA GGAAGAATGT CTCATGTTCG AGTCTGGGGC CGTGGCAGTG 
CTCTCATCTG CAGAAAAGGA GGCCATTAAA GGCACATATG CCAAAGTGCT GGATGCATAT 
GGACTTTTGG GAGTTTTACG ATTAAATCTT GGTGATACCA TGTTGCATTA TCTGGTCCTA 
GTCACTGGAT GCATGTCTGT TGGGAAAATT CAAGAATCTG AAGTCTTCCG AGTTACTTCC 
ACTGAGTTTA TATCACTTCG AGTTGATGCT TCAGATGAGG ACCGCATTTC AGAAGTACGA 
AAGGTTTTGA ACTCAGGAAA CTTTTATTTT GCATGGTCTG CATCTGGAGT CAGCTTAGAT 
CTGAGTCTGA ACGCACATCG AAGCATGCAG GAGCACACAA CTGACAATAG GTTTTTCTGG 
AATCAGTCTT TGCATCTGCA TCTCAAGCAC TATGGTGTGA ATTGTGATGA CTGGTTGTTA 
CGGCTCATGT GTGGAGGAGT AGAGATTAGA ACAATTTATG CTGCCCATAA ACAGGCAAAA 
GCTTGCCTCA TTTCAAGACT AAGCTGTGAG CGAGCTGGGA CAAGGTTCAA CGTCCGGGGA 
ACAAATGATG ACGGTCATGT TGCCAACTTT GTAGAGACAG AGCAGGTTAT ATACTTAGAT 
GACTGTGTCT CCTCCTTCAT ACAAATCCGA GGATCTGTTC CGTTGTTCTG GGAGCAACCA 
GGGTTGCAAG TGGGATCTCA TCGTGTTCGA ATGTCAAGGG GATTTGAAGC CAATGCGCCT 
GCCTTTGACA GGCATTTCCG AACCCTTAAG GACTTATATG GTAAACAAAT AGTAGTAAAT 
CTGCTTGGAT CTAAGGAGGG TGAGCATATG CTGAGCAAGG CCTTCCAGAG TCACTTGAAA 
GCCTCTGAAC ACGCTTCTGA TATCCACATG GTGTCCTTTG ATTATCATCA AATGGTTAAA 
GGAGGAAAGG CAGAAAAATT GCACAGTGTT CTCAAACCAC AAGTCCAGAA GTTTCTAGAT 
TATGGATTTT TTTATTTCGA TGGCAGTGCA GTTCAAAGGT GCCAGAGTGG TACAGTTCGG 
ACAAACTGCC TGGACTGTCT GGATAGAACA AACAGTGTGC AGGCGTTCCT TGGCTTAGAG 
ATGCTAGCTA AACAGCTGGA AGCTCTGGGC TTGGCTGAAA AGCCTCAGTT GGTGACTCGC 
TTTCAAGAAG TTTTCCGGTC CATGTGGTCT GTGAATGGCG ATTCAATCAG TAAAATATAT 
GCAGGCACCG GAGCCCTGGA AGGGAAGGCC AAGTTAAAAG ATGGTGCGCG ATCTGTCACC 
AGAACCATTC AGAATAACTT CTTCGACAGC TCCAAGCAAG AAGCCATTGA TGTTCTGCTT 
CTGGGAAACA CTCTGAACAG CGACTTAGCC GACAAAGCCC GGGCACTTCT AACTACTGGG 
AGTTTGCGTG TGTCTGAACA GACATTACAG TCAGCATCTT CCAAAGTCTT AAAGAACATG 
TGTGAGAACT TCTACAAGTA CTCAAAGCCC AAGAAGATCC GAGTGTGTGT TGGAACCTGG 
AATGTGAACG GCGGGAAACA GTTCCGCAGC ATAGCATTCA AGAACCAGAC CCTCACCGAC 
TGGCTTCTTG ATGCACCCAA GTTAGCTGGC ATCCAGGAGT TTCAAGATAA GAGAAGTAAG 
CCAACTGATA TATTTGCAAT TGGCTTTGAA GAAATGGTGG AGCTGAATGC TGGGAACATT 
GTGAATGCAA GCACAACAAA CCAGAAGCTG TGGGCAGTGG AACTGCAGAA GACCATCTCC 
AGAGACAACA AGTATGTTCT CCTGGCCTCG GAGCAGTTGG TGGGTGTCTG CCTGTTTGTC 
TTTATCAGAC CGCAGCATGC TCCCTTTATC AGGGATGTTG CAGTCGATAC TGTGAAAACT 
GGGATGGGAG GCGCGACTGG AAATAAGGGC GCTGTTGCAA TCCGGATGCT CTTCCACACC 
ACCAGCCTTT GCTTTGTCTG CAGTCACTTT GCTGCAGGCC AGTCCCAAGT CAAAGAGAGA 
AATGAAGATT TCGTAGAAAT AGCACGAAAA TTGAGTTTCC CCATGGGAAG AATGCTCTTC 
TCCCATGATT ACGTATTCTG GTGTGGTGAT TTCAACTATC GAATCGATCT TCCTAATGAA 
GAAGTTAAAG AGCTCATAAG ACAGCAAAAT TGGGATTCTC TTATAGCTGG AGATCAACTC 
ATCAATCAGA AAAATGCAGG ACAGATCTTT AGAGGATTTT TAGAGGGAAA AGTAACGTTT 
GCTCCAACCT ATAAATATGA CTTGTTTTCC GAAGACTATG ACACCAGTGA AAAGTGCCGC 
ACCCCTGCTT GGACAGACCG AGTCCTCTGG AGAAGGAGGA AGTGGCCTTT TGACAGATCA 
GCTGAAGACT TAGATCTTCT GAATGCTAGT TTCCAAGATG AAAGTAAAAT CCTGTATACA 
TGGACTCCTG GCACCTTGCT GCACTATGGA AGAGCCGAGC TGAAGACTTC TGACCACAGG 
CCCGTTGTCG CCCTGATCGA TATAGATATA TTTGAAGTTG AAGCTGAAGA GAGACAAAAA 
ATTTATAAAG AAGTTATTGC AGTCCAGGGC CCACCGGACG GCACAGTACT GGTCTCAATC 
AAAAGTTCTG CACAAGAGAA TACTTTCTTT GACGATGCTT TAATCGATGA GCTTCTGCAG 
CAGTTTGCAC ACTTCGGCGA AGTTATACTT ATAAGATTCG TAGAAGATAA AATGTGGGTT 
ACATTTTTGG AGGGGAGCTC TGCCTTGAAT GTTCTGAGCC TAAATGGTAA AGAGTTATTA 
AATCGGACTA TAACAATTAC TTTAAAAAGT CCAGACTGGA TCAAAACTTT GGAAGAAGAG 
ATGAGTTTAG AGAAAATCAG TGTCACATTG CCCTCATCAA CCAGTTCCAC CCTGCTCGGT 
GAAGATGCAG AGGTCTCAGC GGACTTTGAC ATGGAAGGTG ATGTCGACGA CTACAGTGCT 
GAGGTGGAGG AGCTTCTTCC TCAGCACCTC CAGCCATCCT CCAGCTCTGG CCTCGGCACC 
TCTCCAAGCT CTTCGCCCCG GACCAGTCCC TGCCAGTCAC CCACAGCACC AGAGTACTCC 
GCACCTTCTC TTCCCATCAG ACCTAGTCGA GCACCATCAA GAACTCCAGG ACCTCTAAGT 
TCACAGGGTG CTCCAGTTGA CACCCAGCCA GCAGCCCAGA AGGAGTCTTC CCAGACCATA 
GAGCCCAAGA GGCCACCCCC TCCCCGCCCA GTTGCTCCTC CAGCACGTCC TGCCCCACCA 
CAGAGGCCAC CTCCACCTTC AGGGGCTAGG AGTCCGGCAC CTGCTAGAAA AGAATTTGGA 
GCACCCAAAA GCCCGGGAAC AGCACGGAAA GATAATATAG GGCGTAATCA GCCTTCCCCT 
CAAGCCGGAC TTGCAGGCCC AGGACCTTCT GGATATGGTG CAGCTAGACC GACAATTCCA 
GCTCGTGCTG GAGTGATCAG TGCCCCTCAG AGCCAGGCTC GGGTGTCTGC TGGAAGGCTG 
ACTCCTGAAA GCCAAAGCAA ACCCTTGGAG ACATCGAAAG GTCCTGCTGT CCTTCCAGAA 
CCACTGAAGC CTCAGGCTGC ATTTCCTCCG CAGCCTTCTC TGCCCACACC TGCTCAAAAG 
TTACAGGACC CACTTGTCCC CATAGCAGCA CCTATGCCTC CCTCCATTCC CCAATCGAAT 
TTGGAAACTC CACCCCTGCC CCCACCTCGG AGCAGGTCAT CTCAAAGCTT GCCTTCAGAC 
TCCTCACCAC AGCTACAACA GGAGCAACCA ACAGGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_445928.2
CDS	142..4020
Translation	MAFSKGFRIYHKLDPPPFSLIVETRHKEECLMFESGAVAVLSSAEKEAIKGTYAKVLDAYGLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLRVDASDEDRISEVRKVLNSGNFYFAWSASGVSLDLSLNAHRSMQEHTTDNRFFWNQSLHLHLKHYGVNCDDWLLRLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVIYLDDCVSSFIQIRGSVPLFWEQPGLQVGSHRVRMSRGFEANAPAFDRHFRTLKDLYGKQIVVNLLGSKEGEHMLSKAFQSHLKASEHASDIHMVSFDYHQMVKGGKAEKLHSVLKPQVQKFLDYGFFYFDGSAVQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTRFQEVFRSMWSVNGDSISKIYAGTGALEGKAKLKDGARSVTRTIQNNFFDSSKQEAIDVLLLGNTLNSDLADKARALLTTGSLRVSEQTLQSASSKVLKNMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGNIVNASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFVEIARKLSFPMGRMLFSHDYVFWCGDFNYRIDLPNEEVKELIRQQNWDSLIAGDQLINQKNAGQIFRGFLEGKVTFAPTYKYDLFSEDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQKIYKEVIAVQGPPDGTVLVSIKSSAQENTFFDDALIDELLQQFAHFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELLNRTITITLKSPDWIKTLEEEMSLEKISVTLPSSTSSTLLGEDAEVSADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTAPEYSAPSLPIRPSRAPSRTPGPLSSQGAPVDTQPAAQKESSQTIEPKRPPPPRPVAPPARPAPPQRPPPPSGARSPAPARKEFGAPKSPGTARKDNIGRNQPSPQAGLAGPGPSGYGAARPTIPARAGVISAPQSQARVSAGRLTPESQSKPLETSKGPAVLPEPLKPQAAFPPQPSLPTPAQKLQDPLVPIAAPMPPSIPQSNLETPPLPPPRSRSSQSLPSDSSPQLQQEQPTG

Target ORF information:

RefSeq Version	NM_053476.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus synaptojanin 1 (Synj1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053476.2

ORF Insert Sequence:

ATGGCGTTCA GCAAAGGATT TCGAATCTAC CACAAATTGG ATCCCCCACC GTTCAGCCTC 
ATAGTGGAAA CTAGGCATAA GGAAGAATGT CTCATGTTCG AGTCTGGGGC CGTGGCAGTG 
CTCTCATCTG CAGAAAAGGA GGCCATTAAA GGCACATATG CCAAAGTGCT GGATGCATAT 
GGACTTTTGG GAGTTTTACG ATTAAATCTT GGTGATACCA TGTTGCATTA TCTGGTCCTA 
GTCACTGGAT GCATGTCTGT TGGGAAAATT CAAGAATCTG AAGTCTTCCG AGTTACTTCC 
ACTGAGTTTA TATCACTTCG AGTTGATGCT TCAGATGAGG ACCGCATTTC AGAAGTACGA 
AAGGTTTTGA ACTCAGGAAA CTTTTATTTT GCATGGTCTG CATCTGGAGT CAGCTTAGAT 
CTGAGTCTGA ACGCACATCG AAGCATGCAG GAGCACACAA CTGACAATAG GTTTTTCTGG 
AATCAGTCTT TGCATCTGCA TCTCAAGCAC TATGGTGTGA ATTGTGATGA CTGGTTGTTA 
CGGCTCATGT GTGGAGGAGT AGAGATTAGA ACAATTTATG CTGCCCATAA ACAGGCAAAA 
GCTTGCCTCA TTTCAAGACT AAGCTGTGAG CGAGCTGGGA CAAGGTTCAA CGTCCGGGGA 
ACAAATGATG ACGGTCATGT TGCCAACTTT GTAGAGACAG AGCAGGTTAT ATACTTAGAT 
GACTGTGTCT CCTCCTTCAT ACAAATCCGA GGATCTGTTC CGTTGTTCTG GGAGCAACCA 
GGGTTGCAAG TGGGATCTCA TCGTGTTCGA ATGTCAAGGG GATTTGAAGC CAATGCGCCT 
GCCTTTGACA GGCATTTCCG AACCCTTAAG GACTTATATG GTAAACAAAT AGTAGTAAAT 
CTGCTTGGAT CTAAGGAGGG TGAGCATATG CTGAGCAAGG CCTTCCAGAG TCACTTGAAA 
GCCTCTGAAC ACGCTTCTGA TATCCACATG GTGTCCTTTG ATTATCATCA AATGGTTAAA 
GGAGGAAAGG CAGAAAAATT GCACAGTGTT CTCAAACCAC AAGTCCAGAA GTTTCTAGAT 
TATGGATTTT TTTATTTCGA TGGCAGTGCA GTTCAAAGGT GCCAGAGTGG TACAGTTCGG 
ACAAACTGCC TGGACTGTCT GGATAGAACA AACAGTGTGC AGGCGTTCCT TGGCTTAGAG 
ATGCTAGCTA AACAGCTGGA AGCTCTGGGC TTGGCTGAAA AGCCTCAGTT GGTGACTCGC 
TTTCAAGAAG TTTTCCGGTC CATGTGGTCT GTGAATGGCG ATTCAATCAG TAAAATATAT 
GCAGGCACCG GAGCCCTGGA AGGGAAGGCC AAGTTAAAAG ATGGTGCGCG ATCTGTCACC 
AGAACCATTC AGAATAACTT CTTCGACAGC TCCAAGCAAG AAGCCATTGA TGTTCTGCTT 
CTGGGAAACA CTCTGAACAG CGACTTAGCC GACAAAGCCC GGGCACTTCT AACTACTGGG 
AGTTTGCGTG TGTCTGAACA GACATTACAG TCAGCATCTT CCAAAGTCTT AAAGAACATG 
TGTGAGAACT TCTACAAGTA CTCAAAGCCC AAGAAGATCC GAGTGTGTGT TGGAACCTGG 
AATGTGAACG GCGGGAAACA GTTCCGCAGC ATAGCATTCA AGAACCAGAC CCTCACCGAC 
TGGCTTCTTG ATGCACCCAA GTTAGCTGGC ATCCAGGAGT TTCAAGATAA GAGAAGTAAG 
CCAACTGATA TATTTGCAAT TGGCTTTGAA GAAATGGTGG AGCTGAATGC TGGGAACATT 
GTGAATGCAA GCACAACAAA CCAGAAGCTG TGGGCAGTGG AACTGCAGAA GACCATCTCC 
AGAGACAACA AGTATGTTCT CCTGGCCTCG GAGCAGTTGG TGGGTGTCTG CCTGTTTGTC 
TTTATCAGAC CGCAGCATGC TCCCTTTATC AGGGATGTTG CAGTCGATAC TGTGAAAACT 
GGGATGGGAG GCGCGACTGG AAATAAGGGC GCTGTTGCAA TCCGGATGCT CTTCCACACC 
ACCAGCCTTT GCTTTGTCTG CAGTCACTTT GCTGCAGGCC AGTCCCAAGT CAAAGAGAGA 
AATGAAGATT TCGTAGAAAT AGCACGAAAA TTGAGTTTCC CCATGGGAAG AATGCTCTTC 
TCCCATGATT ACGTATTCTG GTGTGGTGAT TTCAACTATC GAATCGATCT TCCTAATGAA 
GAAGTTAAAG AGCTCATAAG ACAGCAAAAT TGGGATTCTC TTATAGCTGG AGATCAACTC 
ATCAATCAGA AAAATGCAGG ACAGATCTTT AGAGGATTTT TAGAGGGAAA AGTAACGTTT 
GCTCCAACCT ATAAATATGA CTTGTTTTCC GAAGACTATG ACACCAGTGA AAAGTGCCGC 
ACCCCTGCTT GGACAGACCG AGTCCTCTGG AGAAGGAGGA AGTGGCCTTT TGACAGATCA 
GCTGAAGACT TAGATCTTCT GAATGCTAGT TTCCAAGATG AAAGTAAAAT CCTGTATACA 
TGGACTCCTG GCACCTTGCT GCACTATGGA AGAGCCGAGC TGAAGACTTC TGACCACAGG 
CCCGTTGTCG CCCTGATCGA TATAGATATA TTTGAAGTTG AAGCTGAAGA GAGACAAAAA 
ATTTATAAAG AAGTTATTGC AGTCCAGGGC CCACCGGACG GCACAGTACT GGTCTCAATC 
AAAAGTTCTG CACAAGAGAA TACTTTCTTT GACGATGCTT TAATCGATGA GCTTCTGCAG 
CAGTTTGCAC ACTTCGGCGA AGTTATACTT ATAAGATTCG TAGAAGATAA AATGTGGGTT 
ACATTTTTGG AGGGGAGCTC TGCCTTGAAT GTTCTGAGCC TAAATGGTAA AGAGTTATTA 
AATCGGACTA TAACAATTAC TTTAAAAAGT CCAGACTGGA TCAAAACTTT GGAAGAAGAG 
ATGAGTTTAG AGAAAATCAG TGTCACATTG CCCTCATCAA CCAGTTCCAC CCTGCTCGGT 
GAAGATGCAG AGGTCTCAGC GGACTTTGAC ATGGAAGGTG ATGTCGACGA CTACAGTGCT 
GAGGTGGAGG AGCTTCTTCC TCAGCACCTC CAGCCATCCT CCAGCTCTGG CCTCGGCACC 
TCTCCAAGCT CTTCGCCCCG GACCAGTCCC TGCCAGTCAC CCACAGCACC AGAGTACTCC 
GCACCTTCTC TTCCCATCAG ACCTAGTCGA GCACCATCAA GAACTCCAGG ACCTCTAAGT 
TCACAGGGTG CTCCAGTTGA CACCCAGCCA GCAGCCCAGA AGGAGTCTTC CCAGACCATA 
GAGCCCAAGA GGCCACCCCC TCCCCGCCCA GTTGCTCCTC CAGCACGTCC TGCCCCACCA 
CAGAGGCCAC CTCCACCTTC AGGGGCTAGG AGTCCGGCAC CTGCTAGAAA AGAATTTGGA 
GCACCCAAAA GCCCGGGAAC AGCACGGAAA GATAATATAG GGCGTAATCA GCCTTCCCCT 
CAAGCCGGAC TTGCAGGCCC AGGACCTTCT GGATATGGTG CAGCTAGACC GACAATTCCA 
GCTCGTGCTG GAGTGATCAG TGCCCCTCAG AGCCAGGCTC GGGTGTCTGC TGGAAGGCTG 
ACTCCTGAAA GCCAAAGCAA ACCCTTGGAG ACATCGAAAG GTCCTGCTGT CCTTCCAGAA 
CCACTGAAGC CTCAGGCTGC ATTTCCTCCG CAGCCTTCTC TGCCCACACC TGCTCAAAAG 
TTACAGGACC CACTTGTCCC CATAGCAGCA CCTATGCCTC CCTCCATTCC CCAATCGAAT 
TTGGAAACTC CACCCCTGCC CCCACCTCGG AGCAGGTCAT CTCAAAGCTT GCCTTCAGAC 
TCCTCACCAC AGCTACAACA GGAGCAACCA ACAGGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Impaired intracellular trafficking defines early Parkinson's disease.
Trends in neurosciences38(3)178-88(2015 Mar)
Hunn BH,Cragg SJ,Bolam JP,Spillantini MG,Wade-Martins R

Synaptojanin 1 mutation in Parkinson's disease brings further insight into the neuropathological mechanisms.
BioMed research international2014289728(2014)
Drouet V,Lesage S

Synaptic vesicle endocytosis.
Cold Spring Harbor perspectives in biology4(9)a005645(2012 Sep)
Saheki Y,De Camilli P

Trisomy for synaptojanin1 in Down syndrome is functionally linked to the enlargement of early endosomes.
Human molecular genetics21(14)3156-72(2012 Jul)
Cossec JC,Lavaur J,Berman DE,Rivals I,Hoischen A,Stora S,Ripoll C,Mircher C,Grattau Y,Olivomarin JC,de Chaumont F,Lecourtois M,Antonarakis SE,Veltman JA,Delabar JM,Duyckaerts C,Di Paolo G,Potier MC

Recruitment of endophilin to clathrin-coated pit necks is required for efficient vesicle uncoating after fission.
Neuron72(4)587-601(2011 Nov)
Milosevic I,Giovedi S,Lou X,Raimondi A,Collesi C,Shen H,Paradise S,O'Toole E,Ferguson S,Cremona O,De Camilli P

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Synj1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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