Slc7a8 cDNA ORF clone, Rattus norvegicus(Norway rat)

Increased SLC7A8 expression mediates L-DOPA uptake by renal tubular epithelial cells.
Wu Y, Yin Q, Lin S, Huang X, Xia Q, Chen Z, Zhang X, Yang D
Molecular medicine reports16(1)887-893(2017 Jul)

Up-regulation of L-type amino acid transporter 1 (LAT1) in cultured rat retinal capillary endothelial cells in response to glucose deprivation.
Matsuyama R, Tomi M, Akanuma S, Tabuchi A, Kubo Y, Tachikawa M, Hosoya K
Drug metabolism and pharmacokinetics27(3)317-24(2012)

Hyperammonemia increases the expression and activity of the glutamine/arginine transporter y+ LAT2 in rat cerebral cortex: implications for the nitric oxide/cGMP pathway.
Zieli?ska M, Ruszkiewicz J, Hilgier W, Fr??ko I, Albrecht J
Neurochemistry international58(2)190-5(2011 Feb)

Expression of amino acid transporter LAT1 and 4F2hc in the healing process after the implantation of a tooth ash and plaster of Paris mixture.
Kim SG, Ahn YC, Yoon JH, Kim HK, Park SS, Ahn SG, Endou H, Kanai Y, Park JC, Kim DK
In vivo (Athens, Greece)20(5)591-7(2006 Sep-Oct)

Reabsorption of neutral amino acids mediated by amino acid transporter LAT2 and TAT1 in the basolateral membrane of proximal tubule.
Park SY, Kim JK, Kim IJ, Choi BK, Jung KY, Lee S, Park KJ, Chairoungdua A, Kanai Y, Endou H, Kim DK
Archives of pharmacal research28(4)421-32(2005 Apr)

Data suggest that glucose deprivation sensitivity (model for ischemia) of LAT1 expression in retinal capillary endothelial cells is transcriptionally regulated, and cis-elements within LAT1 promoter region from -162 bp to -155 bp mediate this regulation.
Title: Up-regulation of L-type amino acid transporter 1 (LAT1) in cultured rat retinal capillary endothelial cells in response to glucose deprivation.

Reduced delivery of Arg due to enhanced y+ LAT2-mediated exchange of extracellular Gln for intracellular Arg may contribute to the decrease of nitric oxide/cyclic GMP pathway activity evoked in the brain by hyperammonemia.
Title: Hyperammonemia increases the expression and activity of the glutamine/arginine transporter y+ LAT2 in rat cerebral cortex: implications for the nitric oxide/cGMP pathway.

LAT1 and its subunit 4F2hc are highly expressed in the early stage of new bone formation and may have an important role in providing cells with neutral amino acids, including several essential amino acids, at that stage.
Title: Expression of amino acid transporter LAT1 and 4F2hc in the healing process after the implantation of a tooth ash and plaster of Paris mixture.

Differences in L-DOPA handling between SHR and WKY cells may result from over-expression of LAT1 and LAT2 transporters in the former.
Title: Over-expression of renal LAT1 and LAT2 and enhanced L-DOPA uptake in SHR immortalized renal proximal tubular cells.

Overexpression of renal LAT2 might contribute to enhanced L-DOPA uptake and precedes the onset of hypertension.
Title: Organ-specific overexpression of renal LAT2 and enhanced tubular L-DOPA uptake precede the onset of hypertension.