Stmn2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Stmn2
Entrez Gene ID	84510
Full Name	stathmin 2
Synonyms	Scg10,Scgn10
General protein information	Preferred Names stathmin 2 Names stathmin-2 stathmin-like 2 superior cervical ganglion-10 protein superiorcervical ganglia, neural specific 10
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q23
Summary	regulatory phosphoprotein; involved in promoting microtubule depolymerization and maintenance of long-term synaptic plasticity [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_053440.2	NP_445892.1	stathmin-2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	STMN2	XP_001167275.1
Canis lupus familiaris (dog)	STMN2	XP_860684.1
Danio rerio (zebrafish)	stmn2a	NP_001005923.2
Xenopus tropicalis (tropical clawed frog)	stmn2	NP_001005133.1
Danio rerio (zebrafish)	stmn2b	NP_001019393.1
Homo sapiens (human)	STMN2	NP_008960.2
Bos taurus (cattle)	STMN2	NP_001029794.1
Mus musculus (house mouse)	Stmn2	NP_079561.1
Gallus gallus (chicken)	STMN2	NP_990512.1
	STMN2	XP_001089780.1
Rattus norvegicus (Norway rat)	Stmn2	NP_445892.1

Gene Ontology
Bibliography

Related articles in PubMed

Subcellular Golgi localization of stathmin family proteins is promoted by a specific set of DHHC palmitoyl transferases.
Levy AD, Devignot V, Fukata Y, Fukata M, Sobel A, Chauvin S
Molecular biology of the cell22(11)1930-42(2011 Jun)

Calmyrin1 binds to SCG10 protein (stathmin2) to modulate neurite outgrowth.
Sobczak A, Debowska K, Blazejczyk M, Kreutz MR, Kuznicki J, Wojda U
Biochimica et biophysica acta1813(5)1025-37(2011 May)

SCG10 expression on activation of hepatic stellate cells promotes cell motility through interference with microtubules.
Paradis V, Dargere D, Bieche Y, Asselah T, Marcellin P, Vidaud M, Bedossa P
The American journal of pathology177(4)1791-7(2010 Oct)

KBP interacts with SCG10, linking Goldberg-Shprintzen syndrome to microtubule dynamics and neuronal differentiation.
Alves MM, Burzynski G, Delalande JM, Osinga J, van der Goot A, Dolga AM, de Graaff E, Brooks AS, Metzger M, Eisel UL, Shepherd I, Eggen BJ, Hofstra RM
Human molecular genetics19(18)3642-51(2010 Sep)

Aging, depot origin, and preadipocyte gene expression.
Cartwright MJ, Schlauch K, Lenburg ME, Tchkonia T, Pirtskhalava T, Cartwright A, Thomou T, Kirkland JL
The journals of gerontology. Series A, Biological sciences and medical sciences65(3)242-51(2010 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

palmitoylation of stathmins 2 and 3 likely occurs at the Golgi and is crucial for their specific subcellular localization and trafficking
Title: Subcellular Golgi localization of stathmin family proteins is promoted by a specific set of DHHC palmitoyl transferases.

CaMy1 via SCG10 couples Ca(2+) signals with the dynamics of microtubules during neuronal outgrowth in the developing brain.
Title: Calmyrin1 binds to SCG10 protein (stathmin2) to modulate neurite outgrowth.

Overexpression of SCG10 is associated with Liver Fibrosis.
Title: SCG10 expression on activation of hepatic stellate cells promotes cell motility through interference with microtubules.

KBP-depleted PC12 cells were defective in nerve growth factor-induced differentiation and neurite outgrowth, suggesting that KBP is required for cell differentiation and neurite development.
Title: KBP interacts with SCG10, linking Goldberg-Shprintzen syndrome to microtubule dynamics and neuronal differentiation.

age-related changes in preadipocyte gene expression differ among depots, potentially contributing to fat redistribution and dysfunction.
Title: Aging, depot origin, and preadipocyte gene expression.

The following Stmn2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Stmn2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa13794	NM_053440.2 Latest version!	Rattus norvegicus stathmin 2 (Stmn2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Stmn2 ( NM_053440.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_445892.1 Rattus norvegicus stathmin 2 (Stmn2), mRNA.

Price & Availability↑

CloneID	ORa13794
Clone ID Related Accession (Same CDS sequence)	NM_053440.2
Accession Version	NM_053440.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 540bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-18
Organism	Rattus norvegicus(Norway rat)
Product	stathmin-2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC087660.1. On Dec 26, 2004 this sequence version replaced NM_053440.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC087660.1, AF306458.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGCTAAAA CAGCAATGGC CTACAAGGAA AAAATGAAGG AGCTGTCTAT GCTGTCACTG 
ATCTGCTCCT GCTTCTACCC GGAGCCTCGC AACATCAACA TCTACACCTA CGATGACATG 
GAGGTGAAGC AGATCAACAA GCGTGCTTCC GGCCAGGCTT TCGAGCTGAT CTTAAAGCCC 
CCGTCTCCCA TCTCGGAAGC TCCACGAACT CTAGCTTCTC CAAAGAAGAA AGACCTGTCT 
CTGGAGGAGA TCCAGAAAAA GCTGGAGGCT GCAGAGGGGC GAAGGAAGTC TCAGGAGGCC 
CAGGTGCTGA AGCAGTTGGC AGAGAAGAGG GAGCACGAGC GAGAAGTCCT CCAGAAGGCT 
TTGGAGGAGA ATAACAACTT CAGCAAGATG GCGGAGGAGA AGCTGATCCT GAAAATGGAA 
CAAATTAAGG AAAACCGTGA GGCTAATCTA GCTGCTATCA TTGAACGTCT GCAGGAAAAG 
GAGAGGCATG CTGCCGAGGT GCGCAGGAAC AAGGAACTGC AGGTTGAACT GTCTGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_445892.1
CDS	27..566
Translation	MAKTAMAYKEKMKELSMLSLICSCFYPEPRNINIYTYDDMEVKQINKRASGQAFELILKPPSPISEAPRTLASPKKKDLSLEEIQKKLEAAEGRRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQEKERHAAEVRRNKELQVELSG

Target ORF information:

RefSeq Version	NM_053440.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus stathmin 2 (Stmn2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053440.2

ORF Insert Sequence:

ATGGCTAAAA CAGCAATGGC CTACAAGGAA AAAATGAAGG AGCTGTCTAT GCTGTCACTG 
ATCTGCTCCT GCTTCTACCC GGAGCCTCGC AACATCAACA TCTACACCTA CGATGACATG 
GAGGTGAAGC AGATCAACAA GCGTGCTTCC GGCCAGGCTT TCGAGCTGAT CTTAAAGCCC 
CCGTCTCCCA TCTCGGAAGC TCCACGAACT CTAGCTTCTC CAAAGAAGAA AGACCTGTCT 
CTGGAGGAGA TCCAGAAAAA GCTGGAGGCT GCAGAGGGGC GAAGGAAGTC TCAGGAGGCC 
CAGGTGCTGA AGCAGTTGGC AGAGAAGAGG GAGCACGAGC GAGAAGTCCT CCAGAAGGCT 
TTGGAGGAGA ATAACAACTT CAGCAAGATG GCGGAGGAGA AGCTGATCCT GAAAATGGAA 
CAAATTAAGG AAAACCGTGA GGCTAATCTA GCTGCTATCA TTGAACGTCT GCAGGAAAAG 
GAGAGGCATG CTGCCGAGGT GCGCAGGAAC AAGGAACTGC AGGTTGAACT GTCTGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Subcellular Golgi localization of stathmin family proteins is promoted by a specific set of DHHC palmitoyl transferases.
Molecular biology of the cell22(11)1930-42(2011 Jun)
Levy AD,Devignot V,Fukata Y,Fukata M,Sobel A,Chauvin S

Calmyrin1 binds to SCG10 protein (stathmin2) to modulate neurite outgrowth.
Biochimica et biophysica acta1813(5)1025-37(2011 May)
Sobczak A,Debowska K,Blazejczyk M,Kreutz MR,Kuznicki J,Wojda U

SCG10 expression on activation of hepatic stellate cells promotes cell motility through interference with microtubules.
The American journal of pathology177(4)1791-7(2010 Oct)
Paradis V,Dargere D,Bieche Y,Asselah T,Marcellin P,Vidaud M,Bedossa P

KBP interacts with SCG10, linking Goldberg-Shprintzen syndrome to microtubule dynamics and neuronal differentiation.
Human molecular genetics19(18)3642-51(2010 Sep)
Alves MM,Burzynski G,Delalande JM,Osinga J,van der Goot A,Dolga AM,de Graaff E,Brooks AS,Metzger M,Eisel UL,Shepherd I,Eggen BJ,Hofstra RM

Aging, depot origin, and preadipocyte gene expression.
The journals of gerontology. Series A, Biological sciences and medical sciences65(3)242-51(2010 Mar)
Cartwright MJ,Schlauch K,Lenburg ME,Tchkonia T,Pirtskhalava T,Cartwright A,Thomou T,Kirkland JL

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

Stmn2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報