Col1a2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Col1a2
Entrez Gene ID	84352
Full Name	collagen type I alpha 2 chain
General protein information	Preferred Names collagen type I alpha 2 chain Names collagen alpha-2(I) chain alpha-2 type I collagen collagen, type I, alpha 2 procollagen, type I, alpha 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 4 Map Location: 4q21
Summary	structural constituent of the extracellular matrix [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_053356.1	NP_445808.1	collagen alpha-2(I) chain precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	COL1A2	XP_001168894.1
Xenopus tropicalis (tropical clawed frog)	col1a2	NP_001072718.1
Rattus norvegicus (Norway rat)	Col1a2	NP_445808.1
Homo sapiens (human)	COL1A2	NP_000080.2
Mus musculus (house mouse)	Col1a2	NP_031769.2
Gallus gallus (chicken)	COL1A2	NP_001073182.2
	COL1A2	XP_001097831.1
Canis lupus familiaris (dog)	COL1A2	NP_001003187.1
Bos taurus (cattle)	COL1A2	NP_776945.1
Danio rerio (zebrafish)	col1a2	NP_892013.2

Gene Ontology
Bibliography

Related articles in PubMed

Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation.
Barallobre-Barreiro J, Gupta SK, Zoccarato A, Kitazume-Taneike R, Fava M, Yin X, Werner T, Hirt MN, Zampetaki A, Viviano A, Chong M, Bern M, Kourliouros A, Domenech N, Willeit P, Shah AM, Jahangiri M, Schaefer L, Fischer JW, Iozzo RV, Viner R, Thum T, Heineke J, Kichler A, Otsu K, Mayr M
Circulation134(11)817-32(2016 Sep)

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.
Barallobre-Barreiro J, Oklu R, Lynch M, Fava M, Baig F, Yin X, Barwari T, Potier DN, Albadawi H, Jahangiri M, Porter KE, Watkins MT, Misra S, Stoughton J, Mayr M
Cardiovascular research110(3)419-30(2016 06)

Effects of fluoride on the ultrastructure and expression of Type I collagen in rat hard tissue.
Yan X, Hao X, Nie Q, Feng C, Wang H, Sun Z, Niu R, Wang J
Chemosphere12836-41(2015 Jun)

Resveratrol inhibits collagen I synthesis by suppressing IGF-1R activation in intestinal fibroblasts.
Li P, Liang ML, Zhu Y, Gong YY, Wang Y, Heng D, Lin L
World journal of gastroenterology20(16)4648-61(2014 Apr)

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.
Abonnenc M, Nabeebaccus AA, Mayr U, Barallobre-Barreiro J, Dong X, Cuello F, Sur S, Drozdov I, Langley SR, Lu R, Stathopoulou K, Didangelos A, Yin X, Zimmermann WH, Shah AM, Zampetaki A, Mayr M
Circulation research113(10)1138-47(2013 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Flouride affected collagen I arrangement and produced ultrastructural changes in bone tissue. Meanwhile, the mRNA expression of COL1A1 and COL1A2 were reduced and the COL I protein levels decreased in the fluorosis group.
Title: Effects of fluoride on the ultrastructure and expression of Type I collagen in rat hard tissue.

Resveratrol effectively inhibits collagen I synthesis in IGF-1-stimulated colonic fibroblasts, partly by inhibiting IGF-1R activation, and SIRT1 is also responsible for the process.
Title: Resveratrol inhibits collagen I synthesis by suppressing IGF-1R activation in intestinal fibroblasts.

The conformational free-energy landscape has been calculated for the unfolding regions of type-I collagen alpha2 chain within the context of the microfibril
Title: Insight into the degradation of type-I collagen fibrils by MMP-8.

MRTF-A is an important regulator of collagen synthesis in lung fibroblasts and exhibits a dependence on both SRF and Sp1 function to enhance collagen expression
Title: Myocardin-related transcription factor-A complexes activate type I collagen expression in lung fibroblasts.

MAA, a proteolytic cleavage fragment of type I collagen alpha2 chain, is an autoantigen in autoimmune anterior uveitis.
Title: Proteolytic cleavage of type I collagen generates an autoantigen in autoimmune uveitis.

The following Col1a2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Col1a2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa09343	NM_053356.1 Latest version!	Rattus norvegicus collagen type I alpha 2 chain (Col1a2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$727.30 $1039.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Col1a2 ( NM_053356.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_445808.1 Rattus norvegicus collagen type I alpha 2 chain (Col1a2), mRNA.

Price & Availability↑

CloneID	ORa09343
Clone ID Related Accession (Same CDS sequence)	NM_053356.1
Accession Version	NM_053356.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4119bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Rattus norvegicus(Norway rat)
Product	collagen alpha-2(I) chain precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF121217.1. On Dec 15, 2013 this sequence version replaced XM_006236080.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF121217.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689595, SAMEA2689596 [ECO:0000348] ##Evidence-Data-END##

ATGCTCAGCT TTGTGGATAC GCGGACTCTG TTGCTGCTTG CAGTAACGTC GTGCCTAGCA 
ACATGCCAAT CTTTACAAAT GGGATCTGTA CGGAAGGGCC CCACTGGAGA CAGAGGACCG 
CGTGGACAAA GGGGCCCAGC AGGTCCCCGA GGCAGAGATG GTGTTGATGG TCCCGTTGGC 
CCTCCTGGTC CCCCTGGTGC CCCTGGCCCC CCTGGTCCCC CTGGCCCCCC TGGTCTTACT 
GGGAACTTTG CTGCTCAGTA TTCTGACAAA GGAGTTTCAG CTGGCCCCGG ACCAATGGGC 
TTAATGGGAC CCAGAGGCCC TCCTGGTGCT GTCGGAGCCC CTGGCCCTCA AGGTTTCCAA 
GGACCTGCTG GTGAGCCTGG TGAGCCCGGA CAAACGGGTC CTGCAGGTTC CCGTGGGCCA 
GCTGGCCCTC CTGGCAAGGC CGGTGAAGAT GGTCACCCTG GAAAACCTGG AAGACCTGGC 
GAGAGAGGAG TCGTTGGGCC ACAAGGTGCT CGTGGTTTCC CTGGGACTCC TGGACTTCCT 
GGCTTCAAAG GCATTCGAGG ACACAACGGT CTGGATGGAT TGAAAGGACA GCCTGGTGCC 
CAGGGTGTGA AGGGTGAACC CGGTGCCCCT GGAGAGAATG GAACCCCAGG TCAAGCAGGA 
GCCCGAGGGC TTCCTGGTGA GAGAGGGCGT GTCGGAGCTC CTGGTCCAGC TGGTGCCCGT 
GGCAGTGATG GCAGTGTTGG CCCCGTCGGC CCTGCTGGTC CCATTGGGTC TGCTGGTCCT 
CCTGGTTTCC CAGGTGCTCC TGGTCCCAAG GGTGAACTTG GGCCTGTTGG TAACCCTGGC 
CCTGCTGGTC CTGCTGGTCC CCGTGGTGAA GCGGGTCTTC CGGGTCTTTC TGGCCCCGTT 
GGACCTCCTG GCAACCCTGG AGCAAATGGC CTCACTGGTG CCAAGGGAGC CACTGGACTC 
CCTGGTGTTG CTGGGGCTCC TGGTCTCCCC GGTCCCCGTG GTATTCCTGG CCCCGTTGGT 
GCTGCTGGTG CCACTGGTCC CAGAGGACTT GTTGGTGAAC CTGGTCCTGC TGGCTCCAAA 
GGAGAGACTG GTAACAAGGG TGAGCCTGGC TCTGCTGGAG CCCAAGGTCC TCCTGGTCCC 
AGCGGTGAAG AAGGAAAGAG AGGGTCCCCT GGAGAGCCTG GATCTGCTGG TCCTGCAGGG 
CCTCCAGGGC TGAGAGGCAG CCCTGGTTCT CGAGGTCTTC CTGGAGCTGA TGGCAGAGCT 
GGTGTGATGG GCCCTCCTGG CAATCGTGGT TCAACTGGCC CTGCTGGAGT CCGAGGTCCT 
AATGGAGATG CCGGTCGCCC TGGAGAACCT GGTCTCATGG GACCCAGAGG TCTTCCCGGG 
TCTCCTGGAA ATGTTGGCCC AGCTGGTAAA GAAGGCCCTG TGGGTCTCCC TGGCATCGAT 
GGCAGACCTG GCCCAATTGG CCCAGCTGGA CCAAGAGGTG AAGCTGGCAA CATCGGATTC 
CCTGGACCCA AAGGCCCCTC TGGTGATCCT GGCAAACCTG GTGAGAAAGG CCATCCCGGT 
CTCGCTGGTG CTCGGGGAGC TCCAGGTCCC GACGGCAACA ATGGTGCTCA GGGCCCTCCT 
GGACCTCAGG GTGTTCAAGG TGGCAAAGGT GAACAGGGCC CTGCTGGTCC TCCAGGCTTC 
CAGGGTCTCC CGGGTCCCTC TGGTACCGCT GGAGAAGTTG GCAAGCCGGG AGAAAGGGGT 
CTTCCCGGTG AATTCGGTCT CCCTGGTCCT GCTGGTCCAA GAGGAGAACG TGGTCCCCCA 
GGTGAGAGTG GAGCTGCTGG TCCTTCTGGT CCTATTGGAA TCCGAGGTCC CTCTGGAGCC 
CCAGGGCCTG ATGGGAACAA GGGTGAAGCT GGTGCAGTCG GTGCTCCAGG CTCTGCTGGT 
GCCTCTGGTC CTGGTGGGCT TCCAGGAGAG AGGGGTGCTG CTGGCATACC TGGAGGCAAA 
GGAGAAAAGG GTGAAACTGG TCTCAGAGGT GAAATCGGCA ACCCTGGTAG AGATGGTGCT 
CGAGGTGCTC CTGGTGCTAT AGGTGCCCCT GGTCCCGCTG GAGCCTCAGG TGACCGGGGC 
GAAGCTGGTG CTGCTGGTCC TTCTGGCCCT GCTGGTCCTC GAGGTAGCCC TGGTGAACGT 
GGTGAGGTTG GTCCTGCTGG CCCCAATGGA TTTGCTGGTC CTGCTGGTTC TGCTGGCCAA 
CCTGGTGCTA AAGGAGAAAA GGGAACCAAA GGGCCTAAGG GAGAAAATGG CATCGTTGGT 
CCAACCGGAC CTGTCGGAGC TGCTGGCCCA TCTGGTCCTA ATGGCCCACC TGGCCCTGCT 
GGAAGTCGTG GTGATGGAGG GCCCCCTGGT ATGACTGGCT TCCCTGGTGC TGCTGGACGG 
ACTGGTCCCC CCGGACCCAG TGGTATTACT GGCCCCCCTG GTCCCCCTGG TGCTGCTGGT 
AAAGAAGGTA TTCGTGGTCC CCGTGGTGAC CAAGGTCCAG TTGGCCGAAC TGGAGAAATA 
GGTGCATCTG GTCCCCCTGG ATTTGCTGGC GAGAAGGGTC CTTCTGGAGA ACCTGGTACC 
ACAGGACCCC CTGGCACTGC AGGTCCTCAG GGTCTTCTTG GTGCTCCCGG TATTCTGGGT 
CTCCCTGGCT CTCGAGGTGA ACGTGGCCAG CCAGGTATTG CTGGTGCTCT GGGTGAACCT 
GGTCCTCTGG GCATTGCAGG CCCTCCTGGG GCCCGTGGTC CCCCTGGTGC TGTGGGCAGT 
CCTGGAGTTA ATGGTGCCCC TGGTGAAGCC GGTCGTGATG GTAACCCTGG CAGTGATGGT 
CCCCCAGGTC GTGATGGTCA ACCCGGACAC AAGGGAGAGC GTGGTTACCC TGGCAACATT 
GGTCCCACTG GTGCTGCAGG TGCTCCTGGT CCTCATGGTT CTGTGGGTCC TGCTGGGAAA 
CATGGAAACC GTGGTGAGCC TGGTCCTGCT GGTTCTGTTG GTCCCGTTGG TGCTGTCGGT 
CCAAGAGGTC CTAGTGGCCC TCAAGGTATT CGAGGTGACA AGGGAGAGCC TGGTGACAAA 
GGGGCCAGAG GTCTTCCTGG CTTAAAAGGA CACAATGGAT TACAGGGTCT TCCTGGTCTT 
GCTGGGCTGC ATGGTGACCA AGGAGCTCCT GGTCCCGTGG GTCCTGCTGG TCCCAGGGGT 
CCTGCTGGTC CTTCTGGCCC CATTGGCAAA GATGGTAGAT CTGGACATCC TGGACCAGTC 
GGTCCTGCTG GCGTTCGTGG CTCTCAGGGT AGCCAAGGTC CCGCTGGTCC CCCTGGTCCC 
CCTGGGCCTC CTGGGCCTCC TGGTGTCAGC GGAGGAGGCT ATGACTTTGG TTTCGAAGGA 
GGCTTCTACA GGGCTGACCA GCCTCGCTCA CAGCCTTCAC TCAGACCCAA GGACTATGAA 
GTTGATGCAA CTCTGAAATC TCTCAATAAC CAAATCGAGA CCCTTCTCAC TCCTGAAGGC 
TCTAGAAAGA ACCCTGCCCG CACATGCCGT GACTTAAGAC TCAGCCACCC AGAGTGGAAG 
AGCGATTACT ACTGGATTGA CCCTAACCAA GGATGCACTA TGGATGCCAT CAAAGTGTAC 
TGCGATTTCT CTACTGGTGA AACCTGCATC CAGGCCCAAC CTGTCAACAC CCCAGCCAAG 
AATGCATACA GCCGTGCCCA GGCCAACAAG CATGTCTGGT TAGGAGAGAC CATCAATGGT 
GGCAGCCAGT TTGAATACAA CGCAGAAGGG GTGTCCTCCA AGGAAATGGC AACTCAGCTC 
GCCTTCATGC GCCTGCTAGC CAACCGTGCT TCTCAGAACA TCACCTACCA CTGCAAGAAC 
AGCATTGCGT ACCTGGACGA GGAGACAGGC CGCCTGAATA AGGCTGTCAT TCTGCAGGGC 
TCCAACGACG TCGAACTTGT TGCTGAGGGC AACAGCAGAT TCACCTACAC TGTCCTTGTC 
GATGGCTGCT CCAAAAAGAC AAATGAATGG GACAAGACAG TCATTGAATA CAAAACGAAT 
AAGCCATCTC GCCTGCCATT CCTTGACATT GCACCTCTGG ACATCGGTGG TACTAACCAA 
GAATTCCGTG TGGAGGTTGG CCCTGTCTGT TTCAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_445808.1
CDS	1..4119
Translation	MLSFVDTRTLLLLAVTSCLATCQSLQMGSVRKGPTGDRGPRGQRGPAGPRGRDGVDGPVGPPGPPGAPGPPGPPGPPGLTGNFAAQYSDKGVSAGPGPMGLMGPRGPPGAVGAPGPQGFQGPAGEPGEPGQTGPAGSRGPAGPPGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAQGVKGEPGAPGENGTPGQAGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGELGPVGNPGPAGPAGPRGEAGLPGLSGPVGPPGNPGANGLTGAKGATGLPGVAGAPGLPGPRGIPGPVGAAGATGPRGLVGEPGPAGSKGETGNKGEPGSAGAQGPPGPSGEEGKRGSPGEPGSAGPAGPPGLRGSPGSRGLPGADGRAGVMGPPGNRGSTGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNVGPAGKEGPVGLPGIDGRPGPIGPAGPRGEAGNIGFPGPKGPSGDPGKPGEKGHPGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPAGPPGFQGLPGPSGTAGEVGKPGERGLPGEFGLPGPAGPRGERGPPGESGAAGPSGPIGIRGPSGAPGPDGNKGEAGAVGAPGSAGASGPGGLPGERGAAGIPGGKGEKGETGLRGEIGNPGRDGARGAPGAIGAPGPAGASGDRGEAGAAGPSGPAGPRGSPGERGEVGPAGPNGFAGPAGSAGQPGAKGEKGTKGPKGENGIVGPTGPVGAAGPSGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGITGPPGPPGAAGKEGIRGPRGDQGPVGRTGEIGASGPPGFAGEKGPSGEPGTTGPPGTAGPQGLLGAPGILGLPGSRGERGQPGIAGALGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGSDGPPGRDGQPGHKGERGYPGNIGPTGAAGAPGPHGSVGPAGKHGNRGEPGPAGSVGPVGAVGPRGPSGPQGIRGDKGEPGDKGARGLPGLKGHNGLQGLPGLAGLHGDQGAPGPVGPAGPRGPAGPSGPIGKDGRSGHPGPVGPAGVRGSQGSQGPAGPPGPPGPPGPPGVSGGGYDFGFEGGFYRADQPRSQPSLRPKDYEVDATLKSLNNQIETLLTPEGSRKNPARTCRDLRLSHPEWKSDYYWIDPNQGCTMDAIKVYCDFSTGETCIQAQPVNTPAKNAYSRAQANKHVWLGETINGGSQFEYNAEGVSSKEMATQLAFMRLLANRASQNITYHCKNSIAYLDEETGRLNKAVILQGSNDVELVAEGNSRFTYTVLVDGCSKKTNEWDKTVIEYKTNKPSRLPFLDIAPLDIGGTNQEFRVEVGPVCFK

Target ORF information:

RefSeq Version	NM_053356.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus collagen type I alpha 2 chain (Col1a2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053356.1

ORF Insert Sequence:

ATGCTCAGCT TTGTGGATAC GCGGACTCTG TTGCTGCTTG CAGTAACGTC GTGCCTAGCA 
ACATGCCAAT CTTTACAAAT GGGATCTGTA CGGAAGGGCC CCACTGGAGA CAGAGGACCG 
CGTGGACAAA GGGGCCCAGC AGGTCCCCGA GGCAGAGATG GTGTTGATGG TCCCGTTGGC 
CCTCCTGGTC CCCCTGGTGC CCCTGGCCCC CCTGGTCCCC CTGGCCCCCC TGGTCTTACT 
GGGAACTTTG CTGCTCAGTA TTCTGACAAA GGAGTTTCAG CTGGCCCCGG ACCAATGGGC 
TTAATGGGAC CCAGAGGCCC TCCTGGTGCT GTCGGAGCCC CTGGCCCTCA AGGTTTCCAA 
GGACCTGCTG GTGAGCCTGG TGAGCCCGGA CAAACGGGTC CTGCAGGTTC CCGTGGGCCA 
GCTGGCCCTC CTGGCAAGGC CGGTGAAGAT GGTCACCCTG GAAAACCTGG AAGACCTGGC 
GAGAGAGGAG TCGTTGGGCC ACAAGGTGCT CGTGGTTTCC CTGGGACTCC TGGACTTCCT 
GGCTTCAAAG GCATTCGAGG ACACAACGGT CTGGATGGAT TGAAAGGACA GCCTGGTGCC 
CAGGGTGTGA AGGGTGAACC CGGTGCCCCT GGAGAGAATG GAACCCCAGG TCAAGCAGGA 
GCCCGAGGGC TTCCTGGTGA GAGAGGGCGT GTCGGAGCTC CTGGTCCAGC TGGTGCCCGT 
GGCAGTGATG GCAGTGTTGG CCCCGTCGGC CCTGCTGGTC CCATTGGGTC TGCTGGTCCT 
CCTGGTTTCC CAGGTGCTCC TGGTCCCAAG GGTGAACTTG GGCCTGTTGG TAACCCTGGC 
CCTGCTGGTC CTGCTGGTCC CCGTGGTGAA GCGGGTCTTC CGGGTCTTTC TGGCCCCGTT 
GGACCTCCTG GCAACCCTGG AGCAAATGGC CTCACTGGTG CCAAGGGAGC CACTGGACTC 
CCTGGTGTTG CTGGGGCTCC TGGTCTCCCC GGTCCCCGTG GTATTCCTGG CCCCGTTGGT 
GCTGCTGGTG CCACTGGTCC CAGAGGACTT GTTGGTGAAC CTGGTCCTGC TGGCTCCAAA 
GGAGAGACTG GTAACAAGGG TGAGCCTGGC TCTGCTGGAG CCCAAGGTCC TCCTGGTCCC 
AGCGGTGAAG AAGGAAAGAG AGGGTCCCCT GGAGAGCCTG GATCTGCTGG TCCTGCAGGG 
CCTCCAGGGC TGAGAGGCAG CCCTGGTTCT CGAGGTCTTC CTGGAGCTGA TGGCAGAGCT 
GGTGTGATGG GCCCTCCTGG CAATCGTGGT TCAACTGGCC CTGCTGGAGT CCGAGGTCCT 
AATGGAGATG CCGGTCGCCC TGGAGAACCT GGTCTCATGG GACCCAGAGG TCTTCCCGGG 
TCTCCTGGAA ATGTTGGCCC AGCTGGTAAA GAAGGCCCTG TGGGTCTCCC TGGCATCGAT 
GGCAGACCTG GCCCAATTGG CCCAGCTGGA CCAAGAGGTG AAGCTGGCAA CATCGGATTC 
CCTGGACCCA AAGGCCCCTC TGGTGATCCT GGCAAACCTG GTGAGAAAGG CCATCCCGGT 
CTCGCTGGTG CTCGGGGAGC TCCAGGTCCC GACGGCAACA ATGGTGCTCA GGGCCCTCCT 
GGACCTCAGG GTGTTCAAGG TGGCAAAGGT GAACAGGGCC CTGCTGGTCC TCCAGGCTTC 
CAGGGTCTCC CGGGTCCCTC TGGTACCGCT GGAGAAGTTG GCAAGCCGGG AGAAAGGGGT 
CTTCCCGGTG AATTCGGTCT CCCTGGTCCT GCTGGTCCAA GAGGAGAACG TGGTCCCCCA 
GGTGAGAGTG GAGCTGCTGG TCCTTCTGGT CCTATTGGAA TCCGAGGTCC CTCTGGAGCC 
CCAGGGCCTG ATGGGAACAA GGGTGAAGCT GGTGCAGTCG GTGCTCCAGG CTCTGCTGGT 
GCCTCTGGTC CTGGTGGGCT TCCAGGAGAG AGGGGTGCTG CTGGCATACC TGGAGGCAAA 
GGAGAAAAGG GTGAAACTGG TCTCAGAGGT GAAATCGGCA ACCCTGGTAG AGATGGTGCT 
CGAGGTGCTC CTGGTGCTAT AGGTGCCCCT GGTCCCGCTG GAGCCTCAGG TGACCGGGGC 
GAAGCTGGTG CTGCTGGTCC TTCTGGCCCT GCTGGTCCTC GAGGTAGCCC TGGTGAACGT 
GGTGAGGTTG GTCCTGCTGG CCCCAATGGA TTTGCTGGTC CTGCTGGTTC TGCTGGCCAA 
CCTGGTGCTA AAGGAGAAAA GGGAACCAAA GGGCCTAAGG GAGAAAATGG CATCGTTGGT 
CCAACCGGAC CTGTCGGAGC TGCTGGCCCA TCTGGTCCTA ATGGCCCACC TGGCCCTGCT 
GGAAGTCGTG GTGATGGAGG GCCCCCTGGT ATGACTGGCT TCCCTGGTGC TGCTGGACGG 
ACTGGTCCCC CCGGACCCAG TGGTATTACT GGCCCCCCTG GTCCCCCTGG TGCTGCTGGT 
AAAGAAGGTA TTCGTGGTCC CCGTGGTGAC CAAGGTCCAG TTGGCCGAAC TGGAGAAATA 
GGTGCATCTG GTCCCCCTGG ATTTGCTGGC GAGAAGGGTC CTTCTGGAGA ACCTGGTACC 
ACAGGACCCC CTGGCACTGC AGGTCCTCAG GGTCTTCTTG GTGCTCCCGG TATTCTGGGT 
CTCCCTGGCT CTCGAGGTGA ACGTGGCCAG CCAGGTATTG CTGGTGCTCT GGGTGAACCT 
GGTCCTCTGG GCATTGCAGG CCCTCCTGGG GCCCGTGGTC CCCCTGGTGC TGTGGGCAGT 
CCTGGAGTTA ATGGTGCCCC TGGTGAAGCC GGTCGTGATG GTAACCCTGG CAGTGATGGT 
CCCCCAGGTC GTGATGGTCA ACCCGGACAC AAGGGAGAGC GTGGTTACCC TGGCAACATT 
GGTCCCACTG GTGCTGCAGG TGCTCCTGGT CCTCATGGTT CTGTGGGTCC TGCTGGGAAA 
CATGGAAACC GTGGTGAGCC TGGTCCTGCT GGTTCTGTTG GTCCCGTTGG TGCTGTCGGT 
CCAAGAGGTC CTAGTGGCCC TCAAGGTATT CGAGGTGACA AGGGAGAGCC TGGTGACAAA 
GGGGCCAGAG GTCTTCCTGG CTTAAAAGGA CACAATGGAT TACAGGGTCT TCCTGGTCTT 
GCTGGGCTGC ATGGTGACCA AGGAGCTCCT GGTCCCGTGG GTCCTGCTGG TCCCAGGGGT 
CCTGCTGGTC CTTCTGGCCC CATTGGCAAA GATGGTAGAT CTGGACATCC TGGACCAGTC 
GGTCCTGCTG GCGTTCGTGG CTCTCAGGGT AGCCAAGGTC CCGCTGGTCC CCCTGGTCCC 
CCTGGGCCTC CTGGGCCTCC TGGTGTCAGC GGAGGAGGCT ATGACTTTGG TTTCGAAGGA 
GGCTTCTACA GGGCTGACCA GCCTCGCTCA CAGCCTTCAC TCAGACCCAA GGACTATGAA 
GTTGATGCAA CTCTGAAATC TCTCAATAAC CAAATCGAGA CCCTTCTCAC TCCTGAAGGC 
TCTAGAAAGA ACCCTGCCCG CACATGCCGT GACTTAAGAC TCAGCCACCC AGAGTGGAAG 
AGCGATTACT ACTGGATTGA CCCTAACCAA GGATGCACTA TGGATGCCAT CAAAGTGTAC 
TGCGATTTCT CTACTGGTGA AACCTGCATC CAGGCCCAAC CTGTCAACAC CCCAGCCAAG 
AATGCATACA GCCGTGCCCA GGCCAACAAG CATGTCTGGT TAGGAGAGAC CATCAATGGT 
GGCAGCCAGT TTGAATACAA CGCAGAAGGG GTGTCCTCCA AGGAAATGGC AACTCAGCTC 
GCCTTCATGC GCCTGCTAGC CAACCGTGCT TCTCAGAACA TCACCTACCA CTGCAAGAAC 
AGCATTGCGT ACCTGGACGA GGAGACAGGC CGCCTGAATA AGGCTGTCAT TCTGCAGGGC 
TCCAACGACG TCGAACTTGT TGCTGAGGGC AACAGCAGAT TCACCTACAC TGTCCTTGTC 
GATGGCTGCT CCAAAAAGAC AAATGAATGG GACAAGACAG TCATTGAATA CAAAACGAAT 
AAGCCATCTC GCCTGCCATT CCTTGACATT GCACCTCTGG ACATCGGTGG TACTAACCAA 
GAATTCCGTG TGGAGGTTGG CCCTGTCTGT TTCAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation.
Circulation134(11)817-32(2016 Sep)
Barallobre-Barreiro J,Gupta SK,Zoccarato A,Kitazume-Taneike R,Fava M,Yin X,Werner T,Hirt MN,Zampetaki A,Viviano A,Chong M,Bern M,Kourliouros A,Domenech N,Willeit P,Shah AM,Jahangiri M,Schaefer L,Fischer JW,Iozzo RV,Viner R,Thum T,Heineke J,Kichler A,Otsu K,Mayr M

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.
Cardiovascular research110(3)419-30(2016 06)
Barallobre-Barreiro J,Oklu R,Lynch M,Fava M,Baig F,Yin X,Barwari T,Potier DN,Albadawi H,Jahangiri M,Porter KE,Watkins MT,Misra S,Stoughton J,Mayr M

Effects of fluoride on the ultrastructure and expression of Type I collagen in rat hard tissue.
Chemosphere12836-41(2015 Jun)
Yan X,Hao X,Nie Q,Feng C,Wang H,Sun Z,Niu R,Wang J

Resveratrol inhibits collagen I synthesis by suppressing IGF-1R activation in intestinal fibroblasts.
World journal of gastroenterology20(16)4648-61(2014 Apr)
Li P,Liang ML,Zhu Y,Gong YY,Wang Y,Heng D,Lin L

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.
Circulation research113(10)1138-47(2013 Oct)
Abonnenc M,Nabeebaccus AA,Mayr U,Barallobre-Barreiro J,Dong X,Cuello F,Sur S,Drozdov I,Langley SR,Lu R,Stathopoulou K,Didangelos A,Yin X,Zimmermann WH,Shah AM,Zampetaki A,Mayr M

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Col1a2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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