Irs3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Irs3
Entrez Gene ID	84021
Full Name	insulin receptor substrate 3
General protein information	Preferred Names insulin receptor substrate 3 Names insulin receptor substrate 3
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 12 Map Location: 12q12
Summary	functions in signal transduction of various hormones [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_017598465.1	XP_017453954.1	insulin receptor substrate 3 isoform X1
NM_032074.1	NP_114463.1	insulin receptor substrate 3

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Irs3	NP_114463.1
Bos taurus (cattle)	LOC532330	XP_002698178.2
Mus musculus (house mouse)	Irs3	NP_034701.1

Gene Ontology
Bibliography

Related articles in PubMed

MicroRNAs: a new ray of hope for diabetes mellitus.
Kumar M, Nath S, Prasad HK, Sharma GD, Li Y
Protein & cell3(10)726-38(2012 Oct)

53BP2S, interacting with insulin receptor substrates, modulates insulin signaling.
Hakuno F, Kurihara S, Watson RT, Pessin JE, Takahashi S
The Journal of biological chemistry282(52)37747-58(2007 Dec)

Altered subcellular distribution of IRS-1 and IRS-3 is associated with defective Akt activation and GLUT4 translocation in insulin-resistant old rat adipocytes.
Villar M, Serrano R, Gallardo N, Carrascosa JM, Martinez C, Andr?s A
Biochimica et biophysica acta1763(2)197-206(2006 Feb)

Cyclic GMP-dependent protein kinase regulates CCAAT enhancer-binding protein beta functions through inhibition of glycogen synthase kinase-3.
Zhao X, Zhuang S, Chen Y, Boss GR, Pilz RB
The Journal of biological chemistry280(38)32683-92(2005 Sep)

Insulin-induced cell cycle progression is impaired in chinese hamster ovary cells overexpressing insulin receptor substrate-3.
Kaburagi Y, Yamashita R, Ito Y, Okochi H, Yamamoto-Honda R, Yasuda K, Sekihara H, Sasazuki T, Kadowaki T, Yazaki Y
Endocrinology145(12)5862-74(2004 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

53BP2S interacts and modulates the insulin signals mediated by insulin receptor substrates.
Title: 53BP2S, interacting with insulin receptor substrates, modulates insulin signaling.

Cyclic GMP-dependent protein kinase increases the DNA binding potential of C/EBPbeta by preventing the negative effects of GSK-3 phosphorylation
Title: Cyclic GMP-dependent protein kinase regulates CCAAT enhancer-binding protein beta functions through inhibition of glycogen synthase kinase-3.

IRS-3 may play a unique role in mitogenesis by inhibiting insulin-stimulated cell cycle progression via a decrease in cyclin D1 and p21 expressions as well as suppression of c-myc mRNA induction
Title: Insulin-induced cell cycle progression is impaired in chinese hamster ovary cells overexpressing insulin receptor substrate-3.

IRS-3 expression blocked glucose/IGF-1 induced IRS-2 translocation from the cytosol to the plasma membrane, dampening IRS-2/IGF-1R interaction and subsequent activation of the PI3K/PKB/GSK3 signaling pathway
Title: IRS-3 inhibits IRS-2-mediated signaling in pancreatic beta-cells.

These results suggest that intracellular localization of IRS-3 is determined by a different mechanism from other IRS proteins, and that IRS-3 possesses a transcription-regulating activity
Title: Insulin receptor substrate-3 functions as transcriptional activator in the nucleus.

The following Irs3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Irs3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa08980	NM_032074.1 Latest version!	Rattus norvegicus insulin receptor substrate 3 (Irs3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa57900	XM_017598465.1 Latest version!	Rattus norvegicus insulin receptor substrate 3 (Irs3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Irs3 ( NM_032074.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_114463.1 Rattus norvegicus insulin receptor substrate 3 (Irs3), mRNA.

Price & Availability↑

CloneID	ORa08980
Clone ID Related Accession (Same CDS sequence)	NM_032074.1
Accession Version	NM_032074.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1485bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-26
Organism	Rattus norvegicus(Norway rat)
Product	insulin receptor substrate 3
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U93880.1. ##Evidence-Data-START## Transcript exon combination :: U93880.1, BC161840.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMEA2689598 [ECO:0000348] ##Evidence-Data-END##

ATGAAGCCTG CAGGTACGGG CCCCACAGTC TCCTCTGGGG GCGAGTCCAC CGACGTGTCC 
CTCGGCCCGC CGTTTCCTTG GCCCTGCCCG CCCGACGTGC GGCTCTGTGG CCATCTGAGG 
AAGCAGAAGT CCCAGCGCCG CCGCTTTTTC GTGCTGCGTG CTGACCCACC ACGGCTGGAG 
TGCTATGAGA GCGAGAAGAA GTTCTTGGCC AGCGGCTGCC GCCCACCTCG ACCCCGGCGT 
ACCGTTAGCC TGGAAGGTGC CTGCACTATT AGCAAGCGCG CGGATGCCCG TCAGCGCCAC 
CTGATCGTCA TCTATACCAG CGACAGCAGC CTGGGCGTGG CGGCGGCCAG TGAAGCAGAG 
CAGCAAACAT GGTACAGCGC CTTGCTCGAG GTGCGCGCCA CCGCCGCTGC AGCTGCTGCC 
ACCGCTATGG GTTTCAGCCC CCAAGAGGCC CCTGAGTCTT GGATCTTCGC CCCGTTCCAG 
GACGTCTGGC CTGTGACACT GCGGTCCAAG GGGCTGGGGA GAGCACCAGG CCTGAGCAGC 
GGCAGCTATC GCCTGTGCCT GGGTTCTGGG GCCCTGAGCC TCCTGCGGAA GCCGGGAAGC 
AAAGGCTCCA GAGACAGCCG GGCAACGCCA CCACCAGTCC TGCGCTTGTC CTTGCTTAGT 
GTGCGCCGCT GCGGCCACGC AGATTCCTTT TTCTTCCTGG AACTCGGGCG CTCAGCGCCC 
ATAGGTCCTG GTGAGCTGTG GCTGCAGGCC CCTGATGCAG TGGTGGCCCA AAGCATTCAT 
GAGACCGTCC TGGCTGCCAT GAAGAGACTG GGGAGCAGTG CAGCCAGTGG CAAAGCTGAG 
GCACCGCTGG GAGATTCTCC AAAGGGGGCT TCTGCAGTCC CTGCCCCAGC ACCATATGAG 
ATCCCTGCTT TGGCACTGGC AGCACAAGCG AGAAGTCCGG GTGAGAGAGC GAAGCAGGAC 
TACGTCAATC CACTGGAAAG GATGGGGTCA GCACCCTCCT ACAGGGGGCC AGATCTGGGT 
GGGGACTACA TCGCCATGGG AATGAGGAAT GACTATGTGC ACATGGGGGG GAAAGCTGCT 
GAGTACATGT GGATGGCGCC CCCAGGTCTC CCTCCCCCCA CCCCTCCCAG GGTAGATCCC 
AGAAAGGAGC CTGAGGATTG TGAGAGCACA GAGTATATGC CCATGAACAG ATTTTTACCG 
GGGCCTCTTT ACTACGAGTT CAAGGCCAGG GAGCCTGAAC ATGGGCATTC TAGTGCCCAG 
TGTAGCATTA GGGACAGATG GAGACCCATG GTGGCTCAGC CCCGCTCTTC CCAAGGGTCA 
GAGCTCTCTG GGGACTACAT GTACATCCCT GACTATCCCA GTGCTAGGCT GGGGTCTCTG 
GACAGCTGCC TCAACTATGT GGACCTGGAC CTAGTCCCTC CCCTGGAGGT TCCTGGAGCG 
GCCCCAGGGA ATAGTCCACA TAGCTATGCC AGCATCAAGT TCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_114463.1
CDS	189..1673
Translation	MKPAGTGPTVSSGGESTDVSLGPPFPWPCPPDVRLCGHLRKQKSQRRRFFVLRADPPRLECYESEKKFLASGCRPPRPRRTVSLEGACTISKRADARQRHLIVIYTSDSSLGVAAASEAEQQTWYSALLEVRATAAAAAATAMGFSPQEAPESWIFAPFQDVWPVTLRSKGLGRAPGLSSGSYRLCLGSGALSLLRKPGSKGSRDSRATPPPVLRLSLLSVRRCGHADSFFFLELGRSAPIGPGELWLQAPDAVVAQSIHETVLAAMKRLGSSAASGKAEAPLGDSPKGASAVPAPAPYEIPALALAAQARSPGERAKQDYVNPLERMGSAPSYRGPDLGGDYIAMGMRNDYVHMGGKAAEYMWMAPPGLPPPTPPRVDPRKEPEDCESTEYMPMNRFLPGPLYYEFKAREPEHGHSSAQCSIRDRWRPMVAQPRSSQGSELSGDYMYIPDYPSARLGSLDSCLNYVDLDLVPPLEVPGAAPGNSPHSYASIKF

Target ORF information:

RefSeq Version	NM_032074.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus insulin receptor substrate 3 (Irs3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032074.1

ORF Insert Sequence:

ATGAAGCCTG CAGGTACGGG CCCCACAGTC TCCTCTGGGG GCGAGTCCAC CGACGTGTCC 
CTCGGCCCGC CGTTTCCTTG GCCCTGCCCG CCCGACGTGC GGCTCTGTGG CCATCTGAGG 
AAGCAGAAGT CCCAGCGCCG CCGCTTTTTC GTGCTGCGTG CTGACCCACC ACGGCTGGAG 
TGCTATGAGA GCGAGAAGAA GTTCTTGGCC AGCGGCTGCC GCCCACCTCG ACCCCGGCGT 
ACCGTTAGCC TGGAAGGTGC CTGCACTATT AGCAAGCGCG CGGATGCCCG TCAGCGCCAC 
CTGATCGTCA TCTATACCAG CGACAGCAGC CTGGGCGTGG CGGCGGCCAG TGAAGCAGAG 
CAGCAAACAT GGTACAGCGC CTTGCTCGAG GTGCGCGCCA CCGCCGCTGC AGCTGCTGCC 
ACCGCTATGG GTTTCAGCCC CCAAGAGGCC CCTGAGTCTT GGATCTTCGC CCCGTTCCAG 
GACGTCTGGC CTGTGACACT GCGGTCCAAG GGGCTGGGGA GAGCACCAGG CCTGAGCAGC 
GGCAGCTATC GCCTGTGCCT GGGTTCTGGG GCCCTGAGCC TCCTGCGGAA GCCGGGAAGC 
AAAGGCTCCA GAGACAGCCG GGCAACGCCA CCACCAGTCC TGCGCTTGTC CTTGCTTAGT 
GTGCGCCGCT GCGGCCACGC AGATTCCTTT TTCTTCCTGG AACTCGGGCG CTCAGCGCCC 
ATAGGTCCTG GTGAGCTGTG GCTGCAGGCC CCTGATGCAG TGGTGGCCCA AAGCATTCAT 
GAGACCGTCC TGGCTGCCAT GAAGAGACTG GGGAGCAGTG CAGCCAGTGG CAAAGCTGAG 
GCACCGCTGG GAGATTCTCC AAAGGGGGCT TCTGCAGTCC CTGCCCCAGC ACCATATGAG 
ATCCCTGCTT TGGCACTGGC AGCACAAGCG AGAAGTCCGG GTGAGAGAGC GAAGCAGGAC 
TACGTCAATC CACTGGAAAG GATGGGGTCA GCACCCTCCT ACAGGGGGCC AGATCTGGGT 
GGGGACTACA TCGCCATGGG AATGAGGAAT GACTATGTGC ACATGGGGGG GAAAGCTGCT 
GAGTACATGT GGATGGCGCC CCCAGGTCTC CCTCCCCCCA CCCCTCCCAG GGTAGATCCC 
AGAAAGGAGC CTGAGGATTG TGAGAGCACA GAGTATATGC CCATGAACAG ATTTTTACCG 
GGGCCTCTTT ACTACGAGTT CAAGGCCAGG GAGCCTGAAC ATGGGCATTC TAGTGCCCAG 
TGTAGCATTA GGGACAGATG GAGACCCATG GTGGCTCAGC CCCGCTCTTC CCAAGGGTCA 
GAGCTCTCTG GGGACTACAT GTACATCCCT GACTATCCCA GTGCTAGGCT GGGGTCTCTG 
GACAGCTGCC TCAACTATGT GGACCTGGAC CTAGTCCCTC CCCTGGAGGT TCCTGGAGCG 
GCCCCAGGGA ATAGTCCACA TAGCTATGCC AGCATCAAGT TCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Irs3 ( XM_017598465.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017453954.1 Rattus norvegicus insulin receptor substrate 3 (Irs3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa57900
Clone ID Related Accession (Same CDS sequence)	XM_017598465.1
Accession Version	XM_017598465.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1485bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	insulin receptor substrate 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005111.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACCCTG CAGGTACGGG CCCCACAGTC TCCTCTGGGG GCGAGTCCAC CGACGTGTCC 
CTCGGCCCGC CGTTTCCTTG GCCCTGCCCG CCCGACGTGC GGCTCTGTGG CCATCTGAGG 
AAGCAGAAGT CCCAGCGCCG CCGCTTTTTC GTGCTGCGTG CTGACCCACC ACGGCTGGAG 
TGCTATGAGA GCGAGAAGAA GTTCTTGGCC AGCGGCTGCC GCCCACCTCG ACCCCGGCGT 
ACCGTTAGCC TGGAAGGTGC CTGCACTATT AGCAAGCGCG CGGATGCCCG TCAGCGCCAC 
CTGATCGTCA TCTATACCAG CGACAGCAGC CTGGGCGTGG CGGCGGCCAG TGAAGCAGAG 
CAGCAAACAT GGTACAGCGC CTTGCTCGAG GTGCGCGCCA CCGCCGCTGC AGCTGCTGCC 
ACCGCTATGG GTTTCAGCCC CCAAGAGGCC CCTGAGTCTT GGATCTTCGC CCCGTTCCAG 
GACGTCTGGC CTGTGACACT GCGGTCCAAG GGGCTGGGGA GAGCACCAGG CCTGAGCAGC 
GGCAGCTATC GCCTGTGCCT GGGTTCTGGG GCCCTGAGCC TCCTGCGGAA GCCGGGAAGC 
AAAGGCTCCA GAGACAGCCG GGCAACGCCA CCACCAGTCC TGCGCTTGTC CTTGCTCAGT 
GTGCGCCGCT GCGGCCACGC AGATTCCTTT TTCTTCCTGG AACTCGGGCG CTCAGCGCCC 
ATAGGTCCTG GTGAGCTGTG GCTGCAGGCC CCTGATGCAG TGGTGGCCCA AAGCATTCAT 
GAGACCGTCC TGGCTGCCAT GAAGAGACTG GGGAGCAGTG CAGCCAGTGG CAAAGCTGAG 
GCACCGCTGG GAGATTCTCC AAAGGGGGCT TCTGCAGTCC CTGCCCCAGC ACCATATGAG 
ATCCCTGCTT TGGCACTGGC AGCACAAGCG AGAAGTCCGG GTGAGAGAGC GAAGCAGGAC 
TACGTCAATC CACTGGAAAG GATGGGGTCA GCACCCTCCT ACAGGGGGCC AGATCTGGGT 
GGGGACTACA TCGCCATGGG AATGAGGAAT GACTATGTGC ACATGGGGGG GAAAGCTGCT 
GAGTACATGT GGATGGCGCC CCCAGGTCTC CCTCCCCCCA CCCCTCCCAG GGTAGATCCC 
AGAAAGGAGC CTGAGGATTG TGAGAGCACA GAGTATATGC CCATGAACAG ATTTTTACCG 
GGGCCTCTTT ACTACGAGTT CAAGGCCAGG GAGCCTGAAC ATGGGCATTC TAGTGCCCAG 
TGTAGCATTA GGGACAGATG GAGACCCACG GTGGCTCAGC CCCGCTCTTC CCAAGGGTCA 
GAGCTCTCTG GGGACTACAT GTACATCCCT GACTATCCCA GTGCTAGGCT GGGGTCTCTG 
GACAGCTGCC TCAACTATGT GGACCTGGAC CTAGTCCCTC CCCTGGAGGT TCCTGGAGCG 
GCCCCAGGGA ATAGTCCACA TAGCTATGCC AGCATCAAGT TCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017453954.1
CDS	1129..2613
Translation	MNPAGTGPTVSSGGESTDVSLGPPFPWPCPPDVRLCGHLRKQKSQRRRFFVLRADPPRLECYESEKKFLASGCRPPRPRRTVSLEGACTISKRADARQRHLIVIYTSDSSLGVAAASEAEQQTWYSALLEVRATAAAAAATAMGFSPQEAPESWIFAPFQDVWPVTLRSKGLGRAPGLSSGSYRLCLGSGALSLLRKPGSKGSRDSRATPPPVLRLSLLSVRRCGHADSFFFLELGRSAPIGPGELWLQAPDAVVAQSIHETVLAAMKRLGSSAASGKAEAPLGDSPKGASAVPAPAPYEIPALALAAQARSPGERAKQDYVNPLERMGSAPSYRGPDLGGDYIAMGMRNDYVHMGGKAAEYMWMAPPGLPPPTPPRVDPRKEPEDCESTEYMPMNRFLPGPLYYEFKAREPEHGHSSAQCSIRDRWRPTVAQPRSSQGSELSGDYMYIPDYPSARLGSLDSCLNYVDLDLVPPLEVPGAAPGNSPHSYASIKF

Target ORF information:

RefSeq Version	XM_017598465.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus insulin receptor substrate 3 (Irs3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017598465.1

ORF Insert Sequence:

ATGAACCCTG CAGGTACGGG CCCCACAGTC TCCTCTGGGG GCGAGTCCAC CGACGTGTCC 
CTCGGCCCGC CGTTTCCTTG GCCCTGCCCG CCCGACGTGC GGCTCTGTGG CCATCTGAGG 
AAGCAGAAGT CCCAGCGCCG CCGCTTTTTC GTGCTGCGTG CTGACCCACC ACGGCTGGAG 
TGCTATGAGA GCGAGAAGAA GTTCTTGGCC AGCGGCTGCC GCCCACCTCG ACCCCGGCGT 
ACCGTTAGCC TGGAAGGTGC CTGCACTATT AGCAAGCGCG CGGATGCCCG TCAGCGCCAC 
CTGATCGTCA TCTATACCAG CGACAGCAGC CTGGGCGTGG CGGCGGCCAG TGAAGCAGAG 
CAGCAAACAT GGTACAGCGC CTTGCTCGAG GTGCGCGCCA CCGCCGCTGC AGCTGCTGCC 
ACCGCTATGG GTTTCAGCCC CCAAGAGGCC CCTGAGTCTT GGATCTTCGC CCCGTTCCAG 
GACGTCTGGC CTGTGACACT GCGGTCCAAG GGGCTGGGGA GAGCACCAGG CCTGAGCAGC 
GGCAGCTATC GCCTGTGCCT GGGTTCTGGG GCCCTGAGCC TCCTGCGGAA GCCGGGAAGC 
AAAGGCTCCA GAGACAGCCG GGCAACGCCA CCACCAGTCC TGCGCTTGTC CTTGCTCAGT 
GTGCGCCGCT GCGGCCACGC AGATTCCTTT TTCTTCCTGG AACTCGGGCG CTCAGCGCCC 
ATAGGTCCTG GTGAGCTGTG GCTGCAGGCC CCTGATGCAG TGGTGGCCCA AAGCATTCAT 
GAGACCGTCC TGGCTGCCAT GAAGAGACTG GGGAGCAGTG CAGCCAGTGG CAAAGCTGAG 
GCACCGCTGG GAGATTCTCC AAAGGGGGCT TCTGCAGTCC CTGCCCCAGC ACCATATGAG 
ATCCCTGCTT TGGCACTGGC AGCACAAGCG AGAAGTCCGG GTGAGAGAGC GAAGCAGGAC 
TACGTCAATC CACTGGAAAG GATGGGGTCA GCACCCTCCT ACAGGGGGCC AGATCTGGGT 
GGGGACTACA TCGCCATGGG AATGAGGAAT GACTATGTGC ACATGGGGGG GAAAGCTGCT 
GAGTACATGT GGATGGCGCC CCCAGGTCTC CCTCCCCCCA CCCCTCCCAG GGTAGATCCC 
AGAAAGGAGC CTGAGGATTG TGAGAGCACA GAGTATATGC CCATGAACAG ATTTTTACCG 
GGGCCTCTTT ACTACGAGTT CAAGGCCAGG GAGCCTGAAC ATGGGCATTC TAGTGCCCAG 
TGTAGCATTA GGGACAGATG GAGACCCACG GTGGCTCAGC CCCGCTCTTC CCAAGGGTCA 
GAGCTCTCTG GGGACTACAT GTACATCCCT GACTATCCCA GTGCTAGGCT GGGGTCTCTG 
GACAGCTGCC TCAACTATGT GGACCTGGAC CTAGTCCCTC CCCTGGAGGT TCCTGGAGCG 
GCCCCAGGGA ATAGTCCACA TAGCTATGCC AGCATCAAGT TCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

MicroRNAs: a new ray of hope for diabetes mellitus.
Protein & cell3(10)726-38(2012 Oct)
Kumar M,Nath S,Prasad HK,Sharma GD,Li Y

53BP2S, interacting with insulin receptor substrates, modulates insulin signaling.
The Journal of biological chemistry282(52)37747-58(2007 Dec)
Hakuno F,Kurihara S,Watson RT,Pessin JE,Takahashi S

Altered subcellular distribution of IRS-1 and IRS-3 is associated with defective Akt activation and GLUT4 translocation in insulin-resistant old rat adipocytes.
Biochimica et biophysica acta1763(2)197-206(2006 Feb)
Villar M,Serrano R,Gallardo N,Carrascosa JM,Martinez C,Andr?s A

Cyclic GMP-dependent protein kinase regulates CCAAT enhancer-binding protein beta functions through inhibition of glycogen synthase kinase-3.
The Journal of biological chemistry280(38)32683-92(2005 Sep)
Zhao X,Zhuang S,Chen Y,Boss GR,Pilz RB

Insulin-induced cell cycle progression is impaired in chinese hamster ovary cells overexpressing insulin receptor substrate-3.
Endocrinology145(12)5862-74(2004 Dec)
Kaburagi Y,Yamashita R,Ito Y,Okochi H,Yamamoto-Honda R,Yasuda K,Sekihara H,Sasazuki T,Kadowaki T,Yazaki Y

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

Irs3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報