Slc1a6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Slc1a6
Entrez Gene ID	84012
Full Name	solute carrier family 1 member 6
Synonyms	EAAT4
General protein information	Preferred Names solute carrier family 1 member 6 Names excitatory amino acid transporter 4 high affinity aspartate/glutamate transporter high-affinity neuronal glutamate transporter sodium-dependent glutamate/aspartate transporter solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 7 Map Location: 7q11
Summary	mediates cotransport of one glutamate molecule with three Na+ ions and one H+ with countertransport of one K+ ion; also has a voltage gated anion transporter activity that is modified by glutamate [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_008765182.2	XP_008763404.1	excitatory amino acid transporter 4 isoform X1
NM_032065.1	NP_114454.1	excitatory amino acid transporter 4

Pathways from BioSystems

Homologies

Bos taurus (cattle)	SLC1A6	NP_001092560.1
Xenopus tropicalis (tropical clawed frog)	LOC100494506	XP_004911063.1
Homo sapiens (human)	SLC1A6	NP_005062.1
Canis lupus familiaris (dog)	SLC1A6	NP_001003137.1
Mus musculus (house mouse)	Slc1a6	NP_033226.1
Danio rerio (zebrafish)	slc1a6	NP_001103173.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP009443	XP_560420.2
Drosophila melanogaster (fruit fly)	Eaat1	NP_001188751.1
Rattus norvegicus (Norway rat)	Slc1a6	NP_114454.1
Gallus gallus (chicken)	SLC1A6	XP_004948711.1

Gene Ontology
Bibliography

Related articles in PubMed

Caveolin-1 Sensitivity of Excitatory Amino Acid Transporters EAAT1, EAAT2, EAAT3, and EAAT4.
Abousaab A, Warsi J, Elvira B, Lang F
The Journal of membrane biology249(3)239-49(2016 06)

Glutamate transporters EAAT4 and EAAT5 are expressed in vestibular hair cells and calyx endings.
Dalet A, Bonsacquet J, Gaboyard-Niay S, Calin-Jageman I, Chidavaenzi RL, Venteo S, Desmadryl G, Goldberg JM, Lysakowski A, Chabbert C
PloS one7(9)e46261(2012)

Substrate-dependent gating of anion channels associated with excitatory amino acid transporter 4.
Machtens JP, Kovermann P, Fahlke C
The Journal of biological chemistry286(27)23780-8(2011 Jul)

Hetero-oligomerization of neuronal glutamate transporters.
Nothmann D, Leinenweber A, Torres-Salazar D, Kovermann P, Hotzy J, Gameiro A, Grewer C, Fahlke C
The Journal of biological chemistry286(5)3935-43(2011 Feb)

Glutamate transporter EAAT4 in Purkinje cells controls intersynaptic diffusion of climbing fiber transmitter mediating inhibition of GABA release from interneurons.
Satake S, Song SY, Konishi S, Imoto K
The European journal of neuroscience32(11)1843-53(2010 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

strate-dependent gating of anion channels associated with excitatory amino acid transporter 4.
Title: Substrate-dependent gating of anion channels associated with excitatory amino acid transporter 4.

EAAT3 and EAAT4, but neither EAAT1 and EAAT2, nor EAAT2 and EAAT3 are capable of co-assembling into heterotrimers. Co-expression of EAAT3 and EAAT4 results in additional appearance of basolateral EAAT3
Title: Hetero-oligomerization of neuronal glutamate transporters.

Data demonstrate that the neuronal glutamate transporter EAAT4 in Purkinje cells plays a critical role in the extrasynaptic diffusion of climbing fiber transmitters.
Title: Glutamate transporter EAAT4 in Purkinje cells controls intersynaptic diffusion of climbing fiber transmitter mediating inhibition of GABA release from interneurons.

our findings of reduced expression of glutamate transporters vGluT1, EAAT2 and EAAT4 reflect altered glial and neuronal properties and suggest reduced glutamate uptake in the cerebral cortex and the hippocampus of helpless animals
Title: Reduced expression of glutamate transporters vGluT1, EAAT2 and EAAT4 in learned helpless rats, an animal model of depression.

The Na+ coupled glutamate carrier EAAT4 is stimulated by PIKfyve, which thus mimics the stimulating effect of the serum and glucocorticoid inducible kinase SGK1.
Title: Regulation of the glutamate transporter EAAT4 by PIKfyve.

The following Slc1a6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slc1a6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa43807	XM_008765182.2 Latest version!	Rattus norvegicus solute carrier family 1 member 6 (Slc1a6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
ORa08948	NM_032065.1 Latest version!	Rattus norvegicus solute carrier family 1 member 6 (Slc1a6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Slc1a6 ( XM_008765182.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008763404.1 Rattus norvegicus solute carrier family 1 member 6 (Slc1a6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa43807
Clone ID Related Accession (Same CDS sequence)	XM_008765182.2
Accession Version	XM_008765182.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1686bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	excitatory amino acid transporter 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) and transcript sequence (NM_032065.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008765182.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 43 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END##

ATGAGCAGCC ACGGCAACAG TCTGTTCCTG AGGGAGAGCG GCGCTGGCGG GGGCTGTCTG 
CAAGGCCTGC AGGACAGTCT GCAGCAGAGA GCACTGCGCA CGCGCTTGCG CCTGCAGACC 
ATGACCCGAG AGCACGTGCG GCGCTTCCTG CGCCGAAATG CCTTCATCTT GCTCACAGTC 
AGCGCTGTGA TCATTGGCGT CAGCCTGGCA TTTGCCTTGC GCCCATACCA GCTCTCCTAC 
CGCCAGATCA AGTACTTCTC TTTTCCTGGT GAGCTGCTCA TGAGGATGCT GCAGATGCTG 
GTGCTACCCC TCATTGTCTC CAGCCTTGTC ACAGGTATGG CATCCTTGGA CAACAAGGCA 
ACAGGGAGGA TGGGAATGAG GGCAGCTGTG TACTACATGG TGACGACCGT CATTGCAGTT 
TTCATCGGCA TCCTAATGGT TACCATCATA CATCCTGGGA AGGGCTCCAA GGAGGGGCTG 
CACCGTGAGG GCCGAATTGA GACTGTTCCA ACAGCTGATG CTTTCATGGA CCTGGTCAGA 
AATATGTTTC CACCAAACCT TGTGGAGGCC TGCTTCAAAC AGTTTAAAAC ACAGTACAGC 
ACACGAGTGG TAACAAGGAC GATTGTAAGG ACAGACAACG GGTCAGAGTT GGGGGCCTCC 
ATTTCTCCTC CATCCTCAGC AGAAAATGAA ACCAGCATCC TGGAAAATGT CACCCGGGCC 
TTGGGCACCC TGCAGGAGGT GATAAGCTTT GAGGAGACTG TGCCTGTACC TGGCTCAGCT 
AATGGCATCA ACGCTTTGGG CCTCGTGGTC TTCTCTGTGG CCTTCGGGCT GGTCATCGGT 
GGCATGAAGC ACAAAGGCCG TGTCCTGAGG GATTTCTTCG ACAGCCTCAA TGAGGCTATT 
ATGAGGCTGG TGGGCATCAT CATCTGGTAT GCACCAGTGG GCATCCTGTT CCTGATTGCT 
GGAAAGATTC TGGAAATGGA AGACATGGCT GTCCTTGGAG GTCAGCTGGG CATGTACACG 
CTGACTGTCA TTGTCGGCTT ATTTCTTCAT GCTGGTGGTG TGTTACCCCT CATCTACTTC 
CTTGTCACAC ATCGGAACCC CTTTCCCTTC ATCGGTGGTA TACTACAGGC ACTCATCACA 
GCCATGGGTA CCTCTTCCAG CTCTGCAACT CTGCCTATCA CTTTCCGATG CCTGGAGGAG 
GGCCTGGGTG TGGACCGCCG CATCACCAGA TTCGTGTTGC CTGTGGGGGC CACTGTCAAC 
ATGGACGGCA CCGCGCTCTA TGAGGCCTTG GCAGCCATCT TTATTGCTCA AGTCAACAAC 
TATGAGCTGA ACCTTGGTCA GATCACCACA ATCAGCATCA CAGCCACAGC TGCCAGCGTA 
GGAGCAGCTG GCATCCCCCA GGCAGGACTG GTTACCATGG TGATTGTGCT CACATCCGTC 
GGCCTGCCCA CAGAGGACAT CACATTGATC ATAGCTGTGG ATTGGTTCCT TGATCGACTT 
CGTACGATGA CCAATGTACT TGGGGACTCA ATTGGAGCAG CTGTCATTGA GCATTTGTCC 
CAACGGGAGC TGGAGCTGCA AGAGGCTGAG CTGACTCTAC CCAGCCTGGG GAAACCCTAT 
AAGTCACTCA TGGCACAAGA AAAGGGGGCA TCAAGGGGTC GGGGAGGTAA TGAGAGTGTC 
ATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008763404.1
CDS	224..1909
Translation	MSSHGNSLFLRESGAGGGCLQGLQDSLQQRALRTRLRLQTMTREHVRRFLRRNAFILLTVSAVIIGVSLAFALRPYQLSYRQIKYFSFPGELLMRMLQMLVLPLIVSSLVTGMASLDNKATGRMGMRAAVYYMVTTVIAVFIGILMVTIIHPGKGSKEGLHREGRIETVPTADAFMDLVRNMFPPNLVEACFKQFKTQYSTRVVTRTIVRTDNGSELGASISPPSSAENETSILENVTRALGTLQEVISFEETVPVPGSANGINALGLVVFSVAFGLVIGGMKHKGRVLRDFFDSLNEAIMRLVGIIIWYAPVGILFLIAGKILEMEDMAVLGGQLGMYTLTVIVGLFLHAGGVLPLIYFLVTHRNPFPFIGGILQALITAMGTSSSSATLPITFRCLEEGLGVDRRITRFVLPVGATVNMDGTALYEALAAIFIAQVNNYELNLGQITTISITATAASVGAAGIPQAGLVTMVIVLTSVGLPTEDITLIIAVDWFLDRLRTMTNVLGDSIGAAVIEHLSQRELELQEAELTLPSLGKPYKSLMAQEKGASRGRGGNESVM

Target ORF information:

RefSeq Version	XM_008765182.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 1 member 6 (Slc1a6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008765182.2

ORF Insert Sequence:

ATGAGCAGCC ACGGCAACAG TCTGTTCCTG AGGGAGAGCG GCGCTGGCGG GGGCTGTCTG 
CAAGGCCTGC AGGACAGTCT GCAGCAGAGA GCACTGCGCA CGCGCTTGCG CCTGCAGACC 
ATGACCCGAG AGCACGTGCG GCGCTTCCTG CGCCGAAATG CCTTCATCTT GCTCACAGTC 
AGCGCTGTGA TCATTGGCGT CAGCCTGGCA TTTGCCTTGC GCCCATACCA GCTCTCCTAC 
CGCCAGATCA AGTACTTCTC TTTTCCTGGT GAGCTGCTCA TGAGGATGCT GCAGATGCTG 
GTGCTACCCC TCATTGTCTC CAGCCTTGTC ACAGGTATGG CATCCTTGGA CAACAAGGCA 
ACAGGGAGGA TGGGAATGAG GGCAGCTGTG TACTACATGG TGACGACCGT CATTGCAGTT 
TTCATCGGCA TCCTAATGGT TACCATCATA CATCCTGGGA AGGGCTCCAA GGAGGGGCTG 
CACCGTGAGG GCCGAATTGA GACTGTTCCA ACAGCTGATG CTTTCATGGA CCTGGTCAGA 
AATATGTTTC CACCAAACCT TGTGGAGGCC TGCTTCAAAC AGTTTAAAAC ACAGTACAGC 
ACACGAGTGG TAACAAGGAC GATTGTAAGG ACAGACAACG GGTCAGAGTT GGGGGCCTCC 
ATTTCTCCTC CATCCTCAGC AGAAAATGAA ACCAGCATCC TGGAAAATGT CACCCGGGCC 
TTGGGCACCC TGCAGGAGGT GATAAGCTTT GAGGAGACTG TGCCTGTACC TGGCTCAGCT 
AATGGCATCA ACGCTTTGGG CCTCGTGGTC TTCTCTGTGG CCTTCGGGCT GGTCATCGGT 
GGCATGAAGC ACAAAGGCCG TGTCCTGAGG GATTTCTTCG ACAGCCTCAA TGAGGCTATT 
ATGAGGCTGG TGGGCATCAT CATCTGGTAT GCACCAGTGG GCATCCTGTT CCTGATTGCT 
GGAAAGATTC TGGAAATGGA AGACATGGCT GTCCTTGGAG GTCAGCTGGG CATGTACACG 
CTGACTGTCA TTGTCGGCTT ATTTCTTCAT GCTGGTGGTG TGTTACCCCT CATCTACTTC 
CTTGTCACAC ATCGGAACCC CTTTCCCTTC ATCGGTGGTA TACTACAGGC ACTCATCACA 
GCCATGGGTA CCTCTTCCAG CTCTGCAACT CTGCCTATCA CTTTCCGATG CCTGGAGGAG 
GGCCTGGGTG TGGACCGCCG CATCACCAGA TTCGTGTTGC CTGTGGGGGC CACTGTCAAC 
ATGGACGGCA CCGCGCTCTA TGAGGCCTTG GCAGCCATCT TTATTGCTCA AGTCAACAAC 
TATGAGCTGA ACCTTGGTCA GATCACCACA ATCAGCATCA CAGCCACAGC TGCCAGCGTA 
GGAGCAGCTG GCATCCCCCA GGCAGGACTG GTTACCATGG TGATTGTGCT CACATCCGTC 
GGCCTGCCCA CAGAGGACAT CACATTGATC ATAGCTGTGG ATTGGTTCCT TGATCGACTT 
CGTACGATGA CCAATGTACT TGGGGACTCA ATTGGAGCAG CTGTCATTGA GCATTTGTCC 
CAACGGGAGC TGGAGCTGCA AGAGGCTGAG CTGACTCTAC CCAGCCTGGG GAAACCCTAT 
AAGTCACTCA TGGCACAAGA AAAGGGGGCA TCAAGGGGTC GGGGAGGTAA TGAGAGTGTC 
ATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc1a6 ( NM_032065.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_114454.1 Rattus norvegicus solute carrier family 1 member 6 (Slc1a6), mRNA.

Price & Availability↑

CloneID	ORa08948
Clone ID Related Accession (Same CDS sequence)	NM_032065.1
Accession Version	NM_032065.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1686bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Rattus norvegicus(Norway rat)
Product	excitatory amino acid transporter 4
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U89608.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U89608.1, AY286330.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGAGCAGCC ACGGCAACAG TCTGTTCCTG AGGGAGAGCG GCGCTGGCGG GGGCTGTCTG 
CAAGGCCTGC AGGACAGTCT GCAGCAGAGA GCACTGCGCA CGCGCTTGCG CCTGCAGACC 
ATGACCCGAG AGCACGTGCG GCGCTTCCTG CGCCGAAATG CCTTCATCTT GCTCACAGTC 
AGCGCTGTGA TCATTGGCGT CAGCCTGGCA TTTGCCTTGC GCCCATATCA GCTCACCTAC 
CGCCAGATCA AGTACTTCTC TTTTCCTGGT GAGCTGCTCA TGAGGATGCT GCAGATGCTG 
GTGCTACCCC TCATTGTCTC CAGCCGGGTC ACAGGTATGG CATCCTTGGA CAACAAGGCA 
ACAGGGAGGA TGGGAATGAG GGCAGCTGTG TACTACATGG TGACGACCGT CATTGCAGTT 
TTCATCGGCA TCCTAATGGT TACCATCATA CATCCTGGGA AGGGCTCCAA GGAGGGGCTG 
CACCGTGAGG GCCGAATTGA GACTGTTCCA ACAGCTGATG CTTTCATGGA CCTGGTCAGA 
AATATGTTTC CACCAAACCT TGTGGAGGCC TGCTTCAAAC AGTTTAAAAC ACAGTACAGC 
ACACGAGTGG TAACAAGGAC GATTGTAAGG ACAGACAACG GGTCAGAGTT GGGGGCCTCC 
ATTTCTCCTC CATCCTCAGC AGAAAATGAA ACCAGCATCC TGGAAAATGT CACCCGGGCC 
TTGGGCACCC TGCAGGAGGT GATAAGCTTT GAGGAGACTG TGCCTGTACC TGGCTCAGCT 
AATGGCATCA ACGCTTTGGG CCTCGTGGTC TTCTCTGTGG CCTTCGGGCT GGTCATCGGT 
GGCATGAAGC ACAAAGGCCG TGTCCTGAGG GATTTCTTCG ACAGCCTCAA TGAGGCTATT 
ATGAGGCTGG TGGGCATCAT CATCTGGTAT GCACCAGTGG GCATCCTGTT CCTGATTGCT 
GGAAAGATTC TGGAAATGGA AGACATGGCT GTCCTTGGAG GTCAGCTGGG CATGTACACG 
CTGACTGTCA TTGTCGGCTT ATTTCTTCAT GCTGGTGGTG TGTTACCCCT CATCTACTTC 
CTTGTCACAC ATCGGAACCC CTTTCCCTTC ATCGGTGGTA TACTACAGGC ACTCATCACA 
GCCATGGGTA CCTCTTCCAG CTCTGCAACT CTGCCTATCA CTTTCCGATG CCTGGAGGAG 
GGCCTGGGTG TGGACCGCCG CATCACCAGA TTCGTGTTGC CTGTGGGGGC CACTGTCAAC 
ATGGACGGCA CCGCGCTCTA TGAGGCCTTG GCAGCCATCT TTATTGCTCA AGTCAACAAC 
TATGAGCTGA ACCTTGGTCA GATCACCACA ATCAGCATCA CAGCCACAGC TGCCAGCGTA 
GGAGCAGCTG GCATCCCCCA GGCAGGACTG GTTACCATGG TGATTGTGCT CACGTCTGTC 
GGCCTGCCCA CAGAGGACAT CACATTGATC ATAGCTGTGG ATTGGTTCCT TGATCGACTT 
CGTACGATGA CCAATGTACT TGGGGACTCA ATTGGAGCAG CTGTCATTGA GCATTTGTCC 
CAACGGGAGC TGGAGCTGCA AGAGGCTGAG CTGACTCTAC CCAGCCTGGG GAAACCCTAT 
AAGTCACTCA TGGCACAAGC CAAGGGGGCA TCAAGGGGTC GGGGAGGTAA TGAGAGTGTC 
ATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_114454.1
CDS	154..1839
Translation	MSSHGNSLFLRESGAGGGCLQGLQDSLQQRALRTRLRLQTMTREHVRRFLRRNAFILLTVSAVIIGVSLAFALRPYQLTYRQIKYFSFPGELLMRMLQMLVLPLIVSSRVTGMASLDNKATGRMGMRAAVYYMVTTVIAVFIGILMVTIIHPGKGSKEGLHREGRIETVPTADAFMDLVRNMFPPNLVEACFKQFKTQYSTRVVTRTIVRTDNGSELGASISPPSSAENETSILENVTRALGTLQEVISFEETVPVPGSANGINALGLVVFSVAFGLVIGGMKHKGRVLRDFFDSLNEAIMRLVGIIIWYAPVGILFLIAGKILEMEDMAVLGGQLGMYTLTVIVGLFLHAGGVLPLIYFLVTHRNPFPFIGGILQALITAMGTSSSSATLPITFRCLEEGLGVDRRITRFVLPVGATVNMDGTALYEALAAIFIAQVNNYELNLGQITTISITATAASVGAAGIPQAGLVTMVIVLTSVGLPTEDITLIIAVDWFLDRLRTMTNVLGDSIGAAVIEHLSQRELELQEAELTLPSLGKPYKSLMAQAKGASRGRGGNESVM

Target ORF information:

RefSeq Version	NM_032065.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 1 member 6 (Slc1a6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032065.1

ORF Insert Sequence:

ATGAGCAGCC ACGGCAACAG TCTGTTCCTG AGGGAGAGCG GCGCTGGCGG GGGCTGTCTG 
CAAGGCCTGC AGGACAGTCT GCAGCAGAGA GCACTGCGCA CGCGCTTGCG CCTGCAGACC 
ATGACCCGAG AGCACGTGCG GCGCTTCCTG CGCCGAAATG CCTTCATCTT GCTCACAGTC 
AGCGCTGTGA TCATTGGCGT CAGCCTGGCA TTTGCCTTGC GCCCATATCA GCTCACCTAC 
CGCCAGATCA AGTACTTCTC TTTTCCTGGT GAGCTGCTCA TGAGGATGCT GCAGATGCTG 
GTGCTACCCC TCATTGTCTC CAGCCGGGTC ACAGGTATGG CATCCTTGGA CAACAAGGCA 
ACAGGGAGGA TGGGAATGAG GGCAGCTGTG TACTACATGG TGACGACCGT CATTGCAGTT 
TTCATCGGCA TCCTAATGGT TACCATCATA CATCCTGGGA AGGGCTCCAA GGAGGGGCTG 
CACCGTGAGG GCCGAATTGA GACTGTTCCA ACAGCTGATG CTTTCATGGA CCTGGTCAGA 
AATATGTTTC CACCAAACCT TGTGGAGGCC TGCTTCAAAC AGTTTAAAAC ACAGTACAGC 
ACACGAGTGG TAACAAGGAC GATTGTAAGG ACAGACAACG GGTCAGAGTT GGGGGCCTCC 
ATTTCTCCTC CATCCTCAGC AGAAAATGAA ACCAGCATCC TGGAAAATGT CACCCGGGCC 
TTGGGCACCC TGCAGGAGGT GATAAGCTTT GAGGAGACTG TGCCTGTACC TGGCTCAGCT 
AATGGCATCA ACGCTTTGGG CCTCGTGGTC TTCTCTGTGG CCTTCGGGCT GGTCATCGGT 
GGCATGAAGC ACAAAGGCCG TGTCCTGAGG GATTTCTTCG ACAGCCTCAA TGAGGCTATT 
ATGAGGCTGG TGGGCATCAT CATCTGGTAT GCACCAGTGG GCATCCTGTT CCTGATTGCT 
GGAAAGATTC TGGAAATGGA AGACATGGCT GTCCTTGGAG GTCAGCTGGG CATGTACACG 
CTGACTGTCA TTGTCGGCTT ATTTCTTCAT GCTGGTGGTG TGTTACCCCT CATCTACTTC 
CTTGTCACAC ATCGGAACCC CTTTCCCTTC ATCGGTGGTA TACTACAGGC ACTCATCACA 
GCCATGGGTA CCTCTTCCAG CTCTGCAACT CTGCCTATCA CTTTCCGATG CCTGGAGGAG 
GGCCTGGGTG TGGACCGCCG CATCACCAGA TTCGTGTTGC CTGTGGGGGC CACTGTCAAC 
ATGGACGGCA CCGCGCTCTA TGAGGCCTTG GCAGCCATCT TTATTGCTCA AGTCAACAAC 
TATGAGCTGA ACCTTGGTCA GATCACCACA ATCAGCATCA CAGCCACAGC TGCCAGCGTA 
GGAGCAGCTG GCATCCCCCA GGCAGGACTG GTTACCATGG TGATTGTGCT CACGTCTGTC 
GGCCTGCCCA CAGAGGACAT CACATTGATC ATAGCTGTGG ATTGGTTCCT TGATCGACTT 
CGTACGATGA CCAATGTACT TGGGGACTCA ATTGGAGCAG CTGTCATTGA GCATTTGTCC 
CAACGGGAGC TGGAGCTGCA AGAGGCTGAG CTGACTCTAC CCAGCCTGGG GAAACCCTAT 
AAGTCACTCA TGGCACAAGC CAAGGGGGCA TCAAGGGGTC GGGGAGGTAA TGAGAGTGTC 
ATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Caveolin-1 Sensitivity of Excitatory Amino Acid Transporters EAAT1, EAAT2, EAAT3, and EAAT4.
The Journal of membrane biology249(3)239-49(2016 06)
Abousaab A,Warsi J,Elvira B,Lang F

Glutamate transporters EAAT4 and EAAT5 are expressed in vestibular hair cells and calyx endings.
PloS one7(9)e46261(2012)
Dalet A,Bonsacquet J,Gaboyard-Niay S,Calin-Jageman I,Chidavaenzi RL,Venteo S,Desmadryl G,Goldberg JM,Lysakowski A,Chabbert C

Substrate-dependent gating of anion channels associated with excitatory amino acid transporter 4.
The Journal of biological chemistry286(27)23780-8(2011 Jul)
Machtens JP,Kovermann P,Fahlke C

Hetero-oligomerization of neuronal glutamate transporters.
The Journal of biological chemistry286(5)3935-43(2011 Feb)
Nothmann D,Leinenweber A,Torres-Salazar D,Kovermann P,Hotzy J,Gameiro A,Grewer C,Fahlke C

Glutamate transporter EAAT4 in Purkinje cells controls intersynaptic diffusion of climbing fiber transmitter mediating inhibition of GABA release from interneurons.
The European journal of neuroscience32(11)1843-53(2010 Dec)
Satake S,Song SY,Konishi S,Imoto K

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Slc1a6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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