Kalrn cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Kalrn
Entrez Gene ID	84009
Full Name	kalirin, RhoGEF kinase
Synonyms	Duo,Hapip,Kalirin
General protein information	Preferred Names kalirin, RhoGEF kinase Names kalirin P-CIP10 PAM COOH-terminal interactor protein 10 cyclin B1 huntingtin-associated protein interacting protein (duo) huntingtin-associated protein-interacting protein protein Duo serine/threonine kinase with Dbl- and pleckstrin homology domain serine/threonine-protein kinase with Dbl- and pleckstrin homology domain
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 11 Map Location: 11q22
Summary	binds the human huntingtin associated protein Hap1 in vitro; has GDP/GTP exchange factor activity for Rho subfamily GTP-binding proteins [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_032062.2	NP_114451.2	kalirin

Pathways from BioSystems

Homologies

Homo sapiens (human)	KALRN	NP_001019831.2
	KALRN	XP_002802737.1
Gallus gallus (chicken)	KALRN	XP_004942990.1
Mus musculus (house mouse)	Kalrn	NP_796331.2
Rattus norvegicus (Norway rat)	Kalrn	NP_114451.2
Bos taurus (cattle)	KALRN	NP_001178293.1
Canis lupus familiaris (dog)	KALRN	XP_535768.3

Gene Ontology
Bibliography

Related articles in PubMed

Brain Region and Isoform-Specific Phosphorylation Alters Kalirin SH2 Domain Interaction Sites and Calpain Sensitivity.
Miller MB, Yan Y, Machida K, Kiraly DD, Levy AD, Wu YI, Lam TT, Abbott T, Koleske AJ, Eipper BA, Mains RE
ACS chemical neuroscience8(7)1554-1569(2017 Jul)

Kalirin, a GEF for Rac1, plays an important role in FSTL-1-mediated glucose uptake in skeletal muscle cells.
Lee HJ, Lee JO, Lee YW, Kim SA, Park SH, Kim HS
Cellular signalling29150-157(2017 Jan)

Orbitofrontal cortex 5-HT2A receptor mediates chronic stress-induced depressive-like behaviors and alterations of spine density and Kalirin7.
Xu C, Ma XM, Chen HB, Zhou MH, Qiao H, An SC
Neuropharmacology1097-17(2016 Oct)

Neurexin-Neuroligin Synaptic Complex Regulates Schizophrenia-Related DISC1/Kal-7/Rac1 "Signalosome".
Owczarek S, Bang ML, Berezin V
Neural plasticity2015167308(2015)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These results suggest that kalirin and Rac1 guanine nucleotide exchange factor play important roles in FSTL-1-mediated glucose regulation in skeletal muscle cells.
Title: Kalirin, a GEF for Rac1, plays an important role in FSTL-1-mediated glucose uptake in skeletal muscle cells.

Chronic unpredictable mild stress alters structural plasticity in the orbitofrontal cortex and is associated with decreased expression of kalirin.
Title: Orbitofrontal cortex 5-HT2A receptor mediates chronic stress-induced depressive-like behaviors and alterations of spine density and Kalirin7.

Results demonstrate that both endogenous kalirin-9 and endogenous kalirin-12 contribute to dendritic maturation in early development.
Title: Kalirin-9 and Kalirin-12 Play Essential Roles in Dendritic Outgrowth and Branching.

Data show that scaffold protein X11alpha modulates kalirin-7 localization in dendrites and recruits it to Golgi outposts.
Title: Scaffold protein X11? interacts with kalirin-7 in dendrites and recruits it to Golgi outposts.

Knock-down of kalirin-7 abolishes AMPA receptor and dendritic spine upregulation normally seen during cocaine withdrawal.
Title: Kalirin-7 mediates cocaine-induced AMPA receptor and spine plasticity, enabling incentive sensitization.

The following Kalrn gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Kalrn cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa12149	NM_032062.2 Latest version!	Rattus norvegicus kalirin, RhoGEF kinase (Kalrn), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	Quote Price

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Kalrn ( NM_032062.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_114451.2 Rattus norvegicus kalirin, RhoGEF kinase (Kalrn), mRNA.

Price & Availability↑

CloneID	ORa12149
Clone ID Related Accession (Same CDS sequence)	NM_032062.2
Accession Version	NM_032062.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 8934bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-17
Organism	Rattus norvegicus(Norway rat)
Product	kalirin
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF230644.1 and AF232669.1. On Apr 23, 2010 this sequence version replaced NM_032062.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.

ATGACGGACC GCTTCTGGGA CCAGTGGTAT CTTTGGTATC TCCGCTTGCT TCGGCTTCTG 
GATCGAGGAT CTTTTCGGAA TGATGGTTTG AAAGCTTCTG ATGTCCTTCC TATCCTAAAG 
GAGAAAGTGG CCTTTGTGTC TGGGGGTCGT GATAAGCGAG GTGGACCCAT CCTGACCTTC 
CCTGCCCGAA CCAATCATGA CAGAATAAGA CAGGAAGACC TACGGAAACT CGTGACGAAT 
TTGGCCAGCG TGCCAAGCGA GGACGTTTGC AAACGTGGCT TCACCGTCAT CATCGACATG 
CGGGGCTCCA AGTGGGACCT CATCAAGCCC CTCCTCAAGA CGCTGCAGGA AGCCTTTCCC 
GCCGAGATCC ATGTGGCCCT CATCATCAAG CCTGACAACT TCTGGCAGAA GCAGAAGACC 
AACTTTGGCA GCTCCAAATT CATCTTTGAG ACGAGCATGG TGTCTGTGGA GGGCCTCACG 
AAGCTGGTGG ACCCCTCCCA GCTGACAGAA GAGTTTGACG GTTCCCTGGA TTACAACCAC 
GAGGAGTGGA TTGAGTTGCG CCTCTCCCTG GAGGAGTTCT TCAACAGTGC GGTCCACCTG 
CTCTCACGCC TCGAGGACCT GCAGGAGATG CTGGCCCGGA AGGAGTTCCC TGTGGATGTG 
GAGGGCTCTC GGAGGCTTAT CGACGAGCAC ACACAACTTA AGAAAAAGGT GCTGAAGGCC 
CCCGTGGAAG AGCTGGACCG GGAGGGGCAG CGGCTACTGC AGTGTATCCG CTGCAGTGAT 
GGCTTCTCAG GGCGCAACTG CATCCCAGGA AGTGCCGACT TCCAGAGCCT TGTACCCAAG 
ATCACCAGCC TCCTGGACAA GCTGCATTCC ACCCGACAAC ACCTGCACCA GATGTGGCAC 
GTCCGAAAGC TCAAGCTGGA TCAGTGCTTC CAGCTGCGGC TCTTCGAGCA GGATGCCGAG 
AAGATGTTCG ACTGGATAAG CCACAACAAG GAGTTATTTC TTCAGAGCCA CACAGAGATC 
GGAGTCAGCT ACCAGCATGC ACTAGACCTC CAGACACAGC ACAATCACTT TGCCATGAAC 
TCCATGAATG CCTATGTCAA CATCAACCGC ATCATGTCTG TCGCATCCCG CCTCTCAGAG 
GCTGGCCATT ATGCCTCCCA GCAAATCAAG CAGATCTCCA CGCAGCTAGA CCAGGAGTGG 
AAGAGCTTTG CTGCTGCCCT GGATGAACGC AGTACAATCC TGGCCATGTC TGCTGTGTTC 
CACCAGAAGG CAGAGCAGTT CCTGTCAGGA GTGGATGCCT GGTGTAAGAT GTGCAGTGAA 
GGCGGCCTTC CTTCTGAGAT GCAGGACCTG GAGCTGGCAA TCCACCATCA CCAGTCCTTG 
TATGAGCAGG TGACCCAGGC CTACACAGAG GTCAGCCAGG ATGGGAAAGC ACTCCTGGAT 
GTCCTGCAGC GTCCCCTGAG CCCTGGGAAC TCCGAGTCCC TCACAGCCAC AGCCAACTAC 
TCCAAGGCGG TACACCAGGT GCTGGATGTG GTACATGAGG TGCTGCACCA CCAGCGGCGG 
CTCGAGAGCA TCTGGCAGCA CCGTAAAGTG CGGCTTCACC AGCGGCTGCA GCTGTGCGTC 
TTCCAGCAGG ATGTGCAGCA GGTGCTGGAC TGGATTGAAA ACCACGGTGA GGCCTTTCTC 
AGCAAACACA CTGGGGTCGG CAAGTCCCTG CATCGGGCAC GGGCATTGCA GAAGAGGCAT 
GATGACTTTG AAGAGGTGGC TCAGAATACA TACACCAATG CGGACAAGCT CCTAGAGGCA 
GCAGAGCAGC TGGCTCAGAC TGGGGAATGT GACCCGGAAG AGATCTACAA GGCTGCCCGA 
CACCTGGAGG TGCGCATCCA AGACTTCGTG CGCAGAGTGG AGCAGCGGAA GCTTCTTCTG 
GACATGTCCG TCTCTTTCCA CACGCACACC AAAGAGCTGT GGACATGGAT GGAAGACCTT 
CAGAAGGAGG TGCTGGAGGA TGTCTGTGCA GACTCTGTGG ATGCGGTCCA GGAACTGATC 
AAGCAGTTCC AGCAGCAGCA GACCGCTACC CTGGACGCCA CTCTCAACGT CATCAAGGAA 
GGCGAAGACC TTATCCAGCA GCTCAGGTCA GCGCCTCCCT CCCTGGGGGA GCCCACCGAG 
GCCAGGGACT CAGCTGTATC CAACAACAAG ACGCCCCACA GTAGTTCCAT CAGCCATATC 
GAGTCTGTCC TCCAGCAGCT GGACGATGCT CAGGTACAGA TGGAGGAGCT GTTTCACGAG 
CGGAAGATCA AGCTGGACAT CTTCCTGCAG CTGCGCATCT TCGAACAGTA CACCATTGAG 
GTCACCGCAG AGCTGGATGC CTGGAATGAG GACTTGCTCC GGCAGATGAA TGACTTCAAC 
ACAGAGGACC TGACCCTGGC AGAGCAGCGG CTACAGCGCC ACACAGAACG GAAGCTTGCC 
ATGAACAACA TGACATTCGA GGTCATCCAG CAGGGCCAGG ACCTGCACCA ATATATCATG 
GAAGTCCAAG CCTCAGGAAT CGAGTTAATC TGTGAGAAGG ACGTTGACCT GGCAGCTCAG 
GTGCAAGAGC TACTGGAATT TCTCCATGAG AAGCAGCACG AACTGGAGCT CAATGCGGAG 
CAGACGCACA AGCGGCTAGA GCAGTGTCTC CAGCTGCGGC ACCTCCAGGC TGAGGTCAAA 
CAGGTTCTGG GATGGATCCG CAATGGAGAG TCCATGCTCA ACGCCAGCCT GGTCAATGCC 
AGCTCTTTGT CTGAGGCAGA GCAGCTACAG CGGGAGCACG AACAGTTCCA GCTAGCCATC 
GAGAAGACGC ACCAGAGCGC CCTGCAGGTA CAGCAGAAGG CAGAGGCACT GCTCCAGGCC 
GGCCACTATG ACGCCGATGC TATCCGGGAA TGTGCGGAGA AGGTGGCCCT CCACTGGCAA 
CAGCTCATGC TAAAGATGGA GGACCGGCTG AAACTCGTCA ATGCCTCTGT GGCCTTTTAC 
AAGACCTCTG AGCAGGTGTG CAGCGTTCTG GAGAGCTTAG AGCAGGAGTA CCGGAGAGAC 
GAAGACTGGT GCGGCGGGAG AGACAAGCTG GGGCCGGCGG CAGAGATGGA CCACGTCATT 
CCACTCCTCA GCAAGCATCT GGAGCAGAAG GAGGCCTTCC TGAAGGCCTG CACTCTGGCA 
CGGCGGAATG CCGAGGTGTT CCTCAAGTAC ATCCACAGGA ACAATGTGAG CATGCCCAGT 
GTTGCCAGCC ACACCAGGGG ACCCGAACAG CAAGTAAAAG CCATCTTGAG TGAGCTCTTG 
CAGAGAGAGA ATCGCGTCCT GCACTTCTGG ACCTTGAAGA AGCGGCGGTT AGACCAGTGT 
CAGCAATATG TGGTGTTTGA ACGCAGTGCT AAACAGGCAC TAGACTGGAT CCAAGAAACA 
GGAGAATATT ACCTCTCAAC CCATACCTCC ACTGGAGAGA CCACAGAGGA GACTCAGGAG 
CTGCTGAAAG AGTATGGAGA ATTCAGGGTG CCTGCCAAGC AAACAAAAGA GAAGGTGAAG 
CTTCTGATCC AGCTAGCAGA CAGCTTTGTG GAAAAGGGCC ACATCCATGC CACAGAGATA 
CGGAAATGGG TGACCACGGT GGACAAGCAC TACCGGGATT TCTCCCTGAG GATGGGGAAG 
TACCGGTACA CCCTGGAGAA AGCCCTGGGA GTCAACACGG AGGATAACAA GGACCTAGAG 
CTGGACATTA TCCCAGCAAG CCTTTCAGAC CGGGAGGTCA AGCTCCGGGA TGCTAACCAC 
GAGGTCAATG AAGAGAAACG GAAGTCAGCT CGAAAGAAAG AATTCATTAT GGCTGAACTG 
CTCCAGACCG AGAAGGCTTA TGTAAGAGAC CTACACGAGT GCTTGGAGAC CTACCTGTGG 
GAAATGACCA GTGGTGTGGA AGAGATACCA CCTGGGATCC TCAATAAGGA GCACATCATC 
TTCGGCAACA TCCAGGAGAT CTATGACTTC CACAACAACA TCTTCCTCAA AGAGCTGGAG 
AAGTACGAGC AGCTGCCTGA GGATGTGGGA CACTGCTTTG TTACCTGGGC AGACAAATTT 
CAGATGTATG TCACCTACTG TAAAAACAAG CCTGATTCCA ACCAGCTGAT CCTGGAGCAC 
GCAGGCACCT TCTTTGATGA GATCCAGCAG CGGCACGGGC TGGCCAACTC CATCTCTTCC 
TACTTAATTA AGCCTGTCCA GAGAGTTACG AAGTACCAGC TGCTCCTGAA GGAACTTTTA 
ACTTGCTGTG AAGAAGGGAA AGGGGAGCTC AAGGATGGCC TGGAGGTGAT GCTCAGTGTC 
CCCAAGAAAG CCAATGATGC CATGCATGTC AGCATGCTTG AAGGGTTCGA TGAGAACTTG 
GATGTACAGG GGGAGTTGAT TCTCCAGGAT GCCTTTCAAG TGTGGGACCC AAAGTCGCTG 
ATCCGGAAGG GGCGGGAACG GCATCTGTTC CTCTTTGAGA TCTCCTTGGT GTTTAGCAAA 
GAGATCAAAG ACTCTTCAGG ACACACGAAA TATGTTTACA AGAACAAGCT ACTGACCTCA 
GAGCTGGGTG TGACCGAGCA CGTAGAAGGT GACCCCTGCA AATTCGCCTT GTGGTCTGGG 
CGCACCCCAT CCTCAGACAA TAAAACAGTG CTCAAAGCTT CCAACATCGA AACCAAGCAG 
GAATGGATCA AGAACATTCG GGAAGTGATT CAGGAAAGGA TCATTCATCT TAAAGGAGCT 
TTAAAGGAGC CAATCCAGCT CCCCAAAACA CCAGCCAAAC TGAGGAACAA TAGTAAGAGG 
GATGGGGTAG AGGATGGTGA CAGCCAGGGG GACGGGAGCA GCCAGCCCGA TACCATATCC 
ATTGCCTCCA GGACCTCTCA GAACACAGTG GAGAGTGACA AGCTCTCAGG TGGATGTGAG 
CTGACCGTGG TCCTCCAGGA CTTCAGCGCG GCCCACAGCA GTGAGCTGAG CATCCAGGTG 
GGGCAGACTG TGGAGCTGTT GGAACGACCC AGTGAGAGAC CCGGCTGGTG TCTGGTCCGC 
ACCACAGAGC GGAGCCCCCC ACAGGAAGGC CTGGTCCCCA GCAGCACCTT GTGCATCTCA 
CACTCGAGAA GCAGCGTGGA AATGGACTGC TTCTTCCCCC TGGTGAAAGA TTCATACTCT 
CATTCCTCCG GTGAGAATGG AGGCAAGTCT GAGTCCGTGG CCAACCTGCA GTCTCAGCCC 
TCCCTGAACT CCATCCACAG TTCCCCTGGT CCCAAGCGCT CCACCAACAC CCTTAAGAAG 
TGGCTGACGA GCCCTGTGCG TCGGCTCAAC AGCGGGAAAG CAGACGGAAA CATCAAAAAG 
CAGAAGAAAG TACGGGATGG GCGGAAGAGC TTCGACCTGG GCTCACCCAA GCCAGGGGAC 
GAGACAACCC CTCAGGGAGA CAGCGCTGAT GAGAAGAGCA AGAAAGGTTG GGGAGAAGAT 
GAGCCAGATG AAGAGTCACA CACACCTCTC CCCCCGCCCA TGAAGATCTT TGACAACGAC 
CCCACCCAGG ATGAGATGTC CTCTTTGCTA GCAGCCCGGC AGGCTCCCAC TGACGTGCCT 
ACTGCTGCAG ACCTTGTCAG TGCAATAGAA AAGTTGGTCA AAAGTAAGCT GACTCTGGAA 
GGAGGCTCTT ACCGGGGGAG CTTGAAGGAC CCTACAGTCT GCCTGAATGA GGGGATGGCC 
CCTCCCACAC CTCCTAGAAA CCTGGAAGAA GAACAGAAAG CCAAGGCTCT AAGAGGCAGG 
ATGTTTGTCC TGAATGAGTT GGTGCAGACA GAGAAGGACT ACGTCAAGGA CCTGGGGATT 
GTGGTGGAGG GCTTCATGAA AAGAATAGAA GAGAAGGGGG TCCCCGAGGA CATGCGAGGG 
AAGGAAAAGA TCGTGTTTGG AAACATCCAC CAGATTTACG ACTGGCATAA AGATTTTTTC 
CTGGCTGAAC TGGAAAAATG CATCCAAGAG CAAGACAGAT TGGCCCAGCT CTTCATTAAA 
CATGAGCGGA AGCTGCACAT CTATGTGTGG TACTGCCAGA ACAAACCACG TTCCGAATAC 
ATCGTGGCTG AATATGATGC CTACTTTGAG GAGGTTAAAC AAGAGATCAA TCAAAGGCTG 
ACCCTTAGTG ACTTCCTCAT CAAGCCCATT CAGAGAATAA CAAAGTACCA GCTGCTACTC 
AAGGACTTCC TGCGGTACAG CGAGAAGGCT GGTTTGGAGT GTTCTGATAT TGAGAAAGCA 
GTGGAGTTAA TGTGCCTTGT CCCCAAGCGC TGTAATGACA TGATGAATCT GGGACGCCTG 
CAGGGCTTTG AGGGCACCCT GACCGCCCAG GGCAAGCTTC TACAGCAGGA CACGTTCTAT 
GTGATTGAGC TGGATGCTGG CATGCAGTCC CGGACCAAGG AGAGGCGTGT GTTTCTCTTT 
GAGCAGATTG TCATCTTTAG TGAACTGCTC CGAAAGGGAT CCCTCACCCC AGGCTACATG 
TTCAAGAGGA GCATCAAGAT GAATTACTTG GTTCTGGAAG AAGATGTGGA TGATGACCCC 
TGCAAATTTG CACTTATGAA CAGGGAGACT TCAGAAAGGG TCATTCTGCA GGCCGCCAAC 
TCAGACATCC AGCAGGCCTG GGTGCAGGAC ATCAACCAAG TCCTAGAAAC ACAGAGGGAC 
TTCTTAAATG CTCTGCAGTC ACCCATCGAG TATCAGCGGA AGGAGAGGAG CACAGCTGTG 
ATCCGGTCCC AGCCCCCTAG GGTTCCTCAA GCCAGCCCCA GGCCCTATTC GTCTGTCCCA 
GTGGGCTCAG AGAAACCCCC CAAGGGCTCC AGCTACAACC CGCCCCTGCC ACCCCTGAAA 
ATATCTACCT CGAATGGCAG TCCAGGGTTC GACTACCACC AGCCTGGGGA CAAGTTTGAC 
GCTAGCAAGC AGAACGACCT GGGAGGCTGC AATGGGACCT CAACCATGGC CGTAATTAAA 
GATTACTATG CACTGAAGGA GAACGAAATC TGTGTGAGCC AAGGTGAGGT GGTCCAGGTC 
CTCGCCGTCA ACCAGCAGAA CATGTGTCTG GTGTACCAGC CTGCCAGCGA CCATTCCCCA 
GCAGCGGAGG GCTGGGTCCC AGGCAGCATC CTGGCACCCC TCACCAAAGC CACAGCGCCG 
GCCGAGAGTA GTGATGAGAG CATCAAGAAG TCATGCTCAT GGCACACTCT ACGCATGAGA 
AAGCGGGCAG ACGTGGAGAA CACGGGTAAA AATGAAGCCA CAGGGCCTCG TAAACCCAAG 
GATATTCTGG GCAACAAAGC CTCTGTTAAA GAGACGAACA GTTCCGAGGA GTCAGAGTGT 
GATGATCTTG ACCCTAATAC TAGTATGGAG ATCTTGAATC CGAATTTCAT CCAGGAAGTG 
GCTCCGGAAT TCCTTGTGCC CTTGGTAGAT GTGACCTGCT TGCTCGGAGA CACAGTACTG 
CTACAGTGCA AAGCCTGTGG GCGGCCAAAG CCTACCATCA CCTGGAAGGG TCCAGATCAG 
AACATCCTAG ACACCGACAA CAGTTCAGCC ACATACACCA TCTCCTCCTG TGATTCTGGG 
GAAAGCACCC TCAAGATCTG CAACCTGATG CCCCAAGACA GCGGGATTTA TACCTGCATA 
GCAACAAATG ACCACGGAAC CGCATCCACG TCTGCTACAG TTAAGGTGCA AGGTGTACCC 
GCAGCCCCCA ATCGCCCAAT CGCACAGGAG AGGAGCTGCA CCTCCGTCAT CCTCCGCTGG 
CTGCCCCCAG CCAGCACCGG AAACTGCACT ATTTCGGGGT ACACAGTGGA GTACCGCGAG 
GAAGGTTCGC AGGTCTGGCA GCAGTCGGTA GCTTCAACCT TGGACACTTA CCTAGTCATT 
GAAGATCTTA GTCCAGGGTG CCCTTATCAG TTCAGGGTCA GCGCCAGCAA CCCCTGGGGA 
ATCAGCCTTC CCAGTGAGCC CTCGGAGTTT GTGCACCTTC CAGAGTACGA TGCAGCTGCT 
GATGGTGCCA CCATTTCTTG GAAGGAAAAT TTTGATTCTG CTTACACCGA ACTGAACGAG 
ATTGGCAGAG GCCGTTTCTC TATTGTAAAG AAATGCATTC ACAAAGCTAC CCGCAAAGAC 
GTTGCTGTGA AATTTGTGAG CAAGAAAATG AAAAAGAAGG AACAGGCTGC GCACGAGGCC 
GCCCTGCTCC AGCACCTGCA GCACCCCCAG TACGTCACCC TCCACGACAC CTACGAGTCC 
CCCACATCCT ACATCCTGAT TTTGGAACTG ATGGATGACG GCCGACTCTT GGACTACCTA 
ATGAATCACG ATGAGCTGAT GGAAGAAAAG GTAGCTTTCT ACATTCGAGA CATCATGGAA 
GCTCTGCAGT ACCTTCACAA CTGCAGGGTG GCACATTTGG ACATAAAGCC TGAAAACCTC 
CTCATTGACC TCCGGATCCC AGTGCCTCGA GTGAAACTCA TCGACTTGGA AGATGCTGTC 
CAGATCTCAG GCCACTTCCA CATCCACCAT CTGCTGGGGA ACCCTGAGTT TGCTGCCCCG 
GAAGTGATCC AAGGCATCCC TGTCTCCCTG GGCACAGACA TCTGGAGCAT CGGGGTTCTG 
ACCTACGTCA TGCTTAGCGG GGTCTCCCCC TTCTTAGATG AGAGCAAAGA GGAGACCTGC 
ATCAACGTGT GCAGGGTGGA CTTCAGCTTC CCCCACGAAT ACTTCTGCGG TGTAAGCAAT 
GCTGCCAGGG ACTTCATCAA CGTCATCTTA CAGGAAGACT TCCGGAGGCG GCCCACAGCA 
GCCACGTGCC TGCAGCATCC GTGGCTGCAG CCCCACAACG GCAGCTACTC CAAGATCCCC 
TTGGATACCT CCCGCCTGGC CTGCTTCATA GAGCGCCGCA AGCACCAGAA TGACGTGCGG 
CCCATTCCCA ATGTCAAAAG TTACATCGTC AACAGGGTGA ACCAGGGGAC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_114451.2
CDS	1..8934
Translation	MTDRFWDQWYLWYLRLLRLLDRGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPILTFPARTNHDRIRQEDLRKLVTNLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEAFPAEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDYNHEEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVLKAPVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQHALDLQTQHNHFAMNSMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSAVFHQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQSLYEQVTQAYTEVSQDGKALLDVLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQLCVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLLEAAEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWMEDLQKEVLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEPTEARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYTIEVTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQYIMEVQASGIELICEKDVDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAEVKQVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIEKTHQSALQVQQKAEALLQAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLESLEQEYRRDEDWCGGRDKLGPAAEMDHVIPLLSKHLEQKEAFLKACTLARRNAEVFLKYIHRNNVSMPSVASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAKQALDWIQETGEYYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVEKGHIHATEIRKWVTTVDKHYRDFSLRMGKYRYTLEKALGVNTEDNKDLELDIIPASLSDREVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPPGILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRVTKYQLLLKELLTCCEEGKGELKDGLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFLFEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKTVLKASNIETKQEWIKNIREVIQERIIHLKGALKEPIQLPKTPAKLRNNSKRDGVEDGDSQGDGSSQPDTISIASRTSQNTVESDKLSGGCELTVVLQDFSAAHSSELSIQVGQTVELLERPSERPGWCLVRTTERSPPQEGLVPSSTLCISHSRSSVEMDCFFPLVKDSYSHSSGENGGKSESVANLQSQPSLNSIHSSPGPKRSTNTLKKWLTSPVRRLNSGKADGNIKKQKKVRDGRKSFDLGSPKPGDETTPQGDSADEKSKKGWGEDEPDEESHTPLPPPMKIFDNDPTQDEMSSLLAARQAPTDVPTAADLVSAIEKLVKSKLTLEGGSYRGSLKDPTVCLNEGMAPPTPPRNLEEEQKAKALRGRMFVLNELVQTEKDYVKDLGIVVEGFMKRIEEKGVPEDMRGKEKIVFGNIHQIYDWHKDFFLAELEKCIQEQDRLAQLFIKHERKLHIYVWYCQNKPRSEYIVAEYDAYFEEVKQEINQRLTLSDFLIKPIQRITKYQLLLKDFLRYSEKAGLECSDIEKAVELMCLVPKRCNDMMNLGRLQGFEGTLTAQGKLLQQDTFYVIELDAGMQSRTKERRVFLFEQIVIFSELLRKGSLTPGYMFKRSIKMNYLVLEEDVDDDPCKFALMNRETSERVILQAANSDIQQAWVQDINQVLETQRDFLNALQSPIEYQRKERSTAVIRSQPPRVPQASPRPYSSVPVGSEKPPKGSSYNPPLPPLKISTSNGSPGFDYHQPGDKFDASKQNDLGGCNGTSTMAVIKDYYALKENEICVSQGEVVQVLAVNQQNMCLVYQPASDHSPAAEGWVPGSILAPLTKATAPAESSDESIKKSCSWHTLRMRKRADVENTGKNEATGPRKPKDILGNKASVKETNSSEESECDDLDPNTSMEILNPNFIQEVAPEFLVPLVDVTCLLGDTVLLQCKACGRPKPTITWKGPDQNILDTDNSSATYTISSCDSGESTLKICNLMPQDSGIYTCIATNDHGTASTSATVKVQGVPAAPNRPIAQERSCTSVILRWLPPASTGNCTISGYTVEYREEGSQVWQQSVASTLDTYLVIEDLSPGCPYQFRVSASNPWGISLPSEPSEFVHLPEYDAAADGATISWKENFDSAYTELNEIGRGRFSIVKKCIHKATRKDVAVKFVSKKMKKKEQAAHEAALLQHLQHPQYVTLHDTYESPTSYILILELMDDGRLLDYLMNHDELMEEKVAFYIRDIMEALQYLHNCRVAHLDIKPENLLIDLRIPVPRVKLIDLEDAVQISGHFHIHHLLGNPEFAAPEVIQGIPVSLGTDIWSIGVLTYVMLSGVSPFLDESKEETCINVCRVDFSFPHEYFCGVSNAARDFINVILQEDFRRRPTAATCLQHPWLQPHNGSYSKIPLDTSRLACFIERRKHQNDVRPIPNVKSYIVNRVNQGT

Target ORF information:

RefSeq Version	NM_032062.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus kalirin, RhoGEF kinase (Kalrn), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032062.2

ORF Insert Sequence:

ATGACGGACC GCTTCTGGGA CCAGTGGTAT CTTTGGTATC TCCGCTTGCT TCGGCTTCTG 
GATCGAGGAT CTTTTCGGAA TGATGGTTTG AAAGCTTCTG ATGTCCTTCC TATCCTAAAG 
GAGAAAGTGG CCTTTGTGTC TGGGGGTCGT GATAAGCGAG GTGGACCCAT CCTGACCTTC 
CCTGCCCGAA CCAATCATGA CAGAATAAGA CAGGAAGACC TACGGAAACT CGTGACGAAT 
TTGGCCAGCG TGCCAAGCGA GGACGTTTGC AAACGTGGCT TCACCGTCAT CATCGACATG 
CGGGGCTCCA AGTGGGACCT CATCAAGCCC CTCCTCAAGA CGCTGCAGGA AGCCTTTCCC 
GCCGAGATCC ATGTGGCCCT CATCATCAAG CCTGACAACT TCTGGCAGAA GCAGAAGACC 
AACTTTGGCA GCTCCAAATT CATCTTTGAG ACGAGCATGG TGTCTGTGGA GGGCCTCACG 
AAGCTGGTGG ACCCCTCCCA GCTGACAGAA GAGTTTGACG GTTCCCTGGA TTACAACCAC 
GAGGAGTGGA TTGAGTTGCG CCTCTCCCTG GAGGAGTTCT TCAACAGTGC GGTCCACCTG 
CTCTCACGCC TCGAGGACCT GCAGGAGATG CTGGCCCGGA AGGAGTTCCC TGTGGATGTG 
GAGGGCTCTC GGAGGCTTAT CGACGAGCAC ACACAACTTA AGAAAAAGGT GCTGAAGGCC 
CCCGTGGAAG AGCTGGACCG GGAGGGGCAG CGGCTACTGC AGTGTATCCG CTGCAGTGAT 
GGCTTCTCAG GGCGCAACTG CATCCCAGGA AGTGCCGACT TCCAGAGCCT TGTACCCAAG 
ATCACCAGCC TCCTGGACAA GCTGCATTCC ACCCGACAAC ACCTGCACCA GATGTGGCAC 
GTCCGAAAGC TCAAGCTGGA TCAGTGCTTC CAGCTGCGGC TCTTCGAGCA GGATGCCGAG 
AAGATGTTCG ACTGGATAAG CCACAACAAG GAGTTATTTC TTCAGAGCCA CACAGAGATC 
GGAGTCAGCT ACCAGCATGC ACTAGACCTC CAGACACAGC ACAATCACTT TGCCATGAAC 
TCCATGAATG CCTATGTCAA CATCAACCGC ATCATGTCTG TCGCATCCCG CCTCTCAGAG 
GCTGGCCATT ATGCCTCCCA GCAAATCAAG CAGATCTCCA CGCAGCTAGA CCAGGAGTGG 
AAGAGCTTTG CTGCTGCCCT GGATGAACGC AGTACAATCC TGGCCATGTC TGCTGTGTTC 
CACCAGAAGG CAGAGCAGTT CCTGTCAGGA GTGGATGCCT GGTGTAAGAT GTGCAGTGAA 
GGCGGCCTTC CTTCTGAGAT GCAGGACCTG GAGCTGGCAA TCCACCATCA CCAGTCCTTG 
TATGAGCAGG TGACCCAGGC CTACACAGAG GTCAGCCAGG ATGGGAAAGC ACTCCTGGAT 
GTCCTGCAGC GTCCCCTGAG CCCTGGGAAC TCCGAGTCCC TCACAGCCAC AGCCAACTAC 
TCCAAGGCGG TACACCAGGT GCTGGATGTG GTACATGAGG TGCTGCACCA CCAGCGGCGG 
CTCGAGAGCA TCTGGCAGCA CCGTAAAGTG CGGCTTCACC AGCGGCTGCA GCTGTGCGTC 
TTCCAGCAGG ATGTGCAGCA GGTGCTGGAC TGGATTGAAA ACCACGGTGA GGCCTTTCTC 
AGCAAACACA CTGGGGTCGG CAAGTCCCTG CATCGGGCAC GGGCATTGCA GAAGAGGCAT 
GATGACTTTG AAGAGGTGGC TCAGAATACA TACACCAATG CGGACAAGCT CCTAGAGGCA 
GCAGAGCAGC TGGCTCAGAC TGGGGAATGT GACCCGGAAG AGATCTACAA GGCTGCCCGA 
CACCTGGAGG TGCGCATCCA AGACTTCGTG CGCAGAGTGG AGCAGCGGAA GCTTCTTCTG 
GACATGTCCG TCTCTTTCCA CACGCACACC AAAGAGCTGT GGACATGGAT GGAAGACCTT 
CAGAAGGAGG TGCTGGAGGA TGTCTGTGCA GACTCTGTGG ATGCGGTCCA GGAACTGATC 
AAGCAGTTCC AGCAGCAGCA GACCGCTACC CTGGACGCCA CTCTCAACGT CATCAAGGAA 
GGCGAAGACC TTATCCAGCA GCTCAGGTCA GCGCCTCCCT CCCTGGGGGA GCCCACCGAG 
GCCAGGGACT CAGCTGTATC CAACAACAAG ACGCCCCACA GTAGTTCCAT CAGCCATATC 
GAGTCTGTCC TCCAGCAGCT GGACGATGCT CAGGTACAGA TGGAGGAGCT GTTTCACGAG 
CGGAAGATCA AGCTGGACAT CTTCCTGCAG CTGCGCATCT TCGAACAGTA CACCATTGAG 
GTCACCGCAG AGCTGGATGC CTGGAATGAG GACTTGCTCC GGCAGATGAA TGACTTCAAC 
ACAGAGGACC TGACCCTGGC AGAGCAGCGG CTACAGCGCC ACACAGAACG GAAGCTTGCC 
ATGAACAACA TGACATTCGA GGTCATCCAG CAGGGCCAGG ACCTGCACCA ATATATCATG 
GAAGTCCAAG CCTCAGGAAT CGAGTTAATC TGTGAGAAGG ACGTTGACCT GGCAGCTCAG 
GTGCAAGAGC TACTGGAATT TCTCCATGAG AAGCAGCACG AACTGGAGCT CAATGCGGAG 
CAGACGCACA AGCGGCTAGA GCAGTGTCTC CAGCTGCGGC ACCTCCAGGC TGAGGTCAAA 
CAGGTTCTGG GATGGATCCG CAATGGAGAG TCCATGCTCA ACGCCAGCCT GGTCAATGCC 
AGCTCTTTGT CTGAGGCAGA GCAGCTACAG CGGGAGCACG AACAGTTCCA GCTAGCCATC 
GAGAAGACGC ACCAGAGCGC CCTGCAGGTA CAGCAGAAGG CAGAGGCACT GCTCCAGGCC 
GGCCACTATG ACGCCGATGC TATCCGGGAA TGTGCGGAGA AGGTGGCCCT CCACTGGCAA 
CAGCTCATGC TAAAGATGGA GGACCGGCTG AAACTCGTCA ATGCCTCTGT GGCCTTTTAC 
AAGACCTCTG AGCAGGTGTG CAGCGTTCTG GAGAGCTTAG AGCAGGAGTA CCGGAGAGAC 
GAAGACTGGT GCGGCGGGAG AGACAAGCTG GGGCCGGCGG CAGAGATGGA CCACGTCATT 
CCACTCCTCA GCAAGCATCT GGAGCAGAAG GAGGCCTTCC TGAAGGCCTG CACTCTGGCA 
CGGCGGAATG CCGAGGTGTT CCTCAAGTAC ATCCACAGGA ACAATGTGAG CATGCCCAGT 
GTTGCCAGCC ACACCAGGGG ACCCGAACAG CAAGTAAAAG CCATCTTGAG TGAGCTCTTG 
CAGAGAGAGA ATCGCGTCCT GCACTTCTGG ACCTTGAAGA AGCGGCGGTT AGACCAGTGT 
CAGCAATATG TGGTGTTTGA ACGCAGTGCT AAACAGGCAC TAGACTGGAT CCAAGAAACA 
GGAGAATATT ACCTCTCAAC CCATACCTCC ACTGGAGAGA CCACAGAGGA GACTCAGGAG 
CTGCTGAAAG AGTATGGAGA ATTCAGGGTG CCTGCCAAGC AAACAAAAGA GAAGGTGAAG 
CTTCTGATCC AGCTAGCAGA CAGCTTTGTG GAAAAGGGCC ACATCCATGC CACAGAGATA 
CGGAAATGGG TGACCACGGT GGACAAGCAC TACCGGGATT TCTCCCTGAG GATGGGGAAG 
TACCGGTACA CCCTGGAGAA AGCCCTGGGA GTCAACACGG AGGATAACAA GGACCTAGAG 
CTGGACATTA TCCCAGCAAG CCTTTCAGAC CGGGAGGTCA AGCTCCGGGA TGCTAACCAC 
GAGGTCAATG AAGAGAAACG GAAGTCAGCT CGAAAGAAAG AATTCATTAT GGCTGAACTG 
CTCCAGACCG AGAAGGCTTA TGTAAGAGAC CTACACGAGT GCTTGGAGAC CTACCTGTGG 
GAAATGACCA GTGGTGTGGA AGAGATACCA CCTGGGATCC TCAATAAGGA GCACATCATC 
TTCGGCAACA TCCAGGAGAT CTATGACTTC CACAACAACA TCTTCCTCAA AGAGCTGGAG 
AAGTACGAGC AGCTGCCTGA GGATGTGGGA CACTGCTTTG TTACCTGGGC AGACAAATTT 
CAGATGTATG TCACCTACTG TAAAAACAAG CCTGATTCCA ACCAGCTGAT CCTGGAGCAC 
GCAGGCACCT TCTTTGATGA GATCCAGCAG CGGCACGGGC TGGCCAACTC CATCTCTTCC 
TACTTAATTA AGCCTGTCCA GAGAGTTACG AAGTACCAGC TGCTCCTGAA GGAACTTTTA 
ACTTGCTGTG AAGAAGGGAA AGGGGAGCTC AAGGATGGCC TGGAGGTGAT GCTCAGTGTC 
CCCAAGAAAG CCAATGATGC CATGCATGTC AGCATGCTTG AAGGGTTCGA TGAGAACTTG 
GATGTACAGG GGGAGTTGAT TCTCCAGGAT GCCTTTCAAG TGTGGGACCC AAAGTCGCTG 
ATCCGGAAGG GGCGGGAACG GCATCTGTTC CTCTTTGAGA TCTCCTTGGT GTTTAGCAAA 
GAGATCAAAG ACTCTTCAGG ACACACGAAA TATGTTTACA AGAACAAGCT ACTGACCTCA 
GAGCTGGGTG TGACCGAGCA CGTAGAAGGT GACCCCTGCA AATTCGCCTT GTGGTCTGGG 
CGCACCCCAT CCTCAGACAA TAAAACAGTG CTCAAAGCTT CCAACATCGA AACCAAGCAG 
GAATGGATCA AGAACATTCG GGAAGTGATT CAGGAAAGGA TCATTCATCT TAAAGGAGCT 
TTAAAGGAGC CAATCCAGCT CCCCAAAACA CCAGCCAAAC TGAGGAACAA TAGTAAGAGG 
GATGGGGTAG AGGATGGTGA CAGCCAGGGG GACGGGAGCA GCCAGCCCGA TACCATATCC 
ATTGCCTCCA GGACCTCTCA GAACACAGTG GAGAGTGACA AGCTCTCAGG TGGATGTGAG 
CTGACCGTGG TCCTCCAGGA CTTCAGCGCG GCCCACAGCA GTGAGCTGAG CATCCAGGTG 
GGGCAGACTG TGGAGCTGTT GGAACGACCC AGTGAGAGAC CCGGCTGGTG TCTGGTCCGC 
ACCACAGAGC GGAGCCCCCC ACAGGAAGGC CTGGTCCCCA GCAGCACCTT GTGCATCTCA 
CACTCGAGAA GCAGCGTGGA AATGGACTGC TTCTTCCCCC TGGTGAAAGA TTCATACTCT 
CATTCCTCCG GTGAGAATGG AGGCAAGTCT GAGTCCGTGG CCAACCTGCA GTCTCAGCCC 
TCCCTGAACT CCATCCACAG TTCCCCTGGT CCCAAGCGCT CCACCAACAC CCTTAAGAAG 
TGGCTGACGA GCCCTGTGCG TCGGCTCAAC AGCGGGAAAG CAGACGGAAA CATCAAAAAG 
CAGAAGAAAG TACGGGATGG GCGGAAGAGC TTCGACCTGG GCTCACCCAA GCCAGGGGAC 
GAGACAACCC CTCAGGGAGA CAGCGCTGAT GAGAAGAGCA AGAAAGGTTG GGGAGAAGAT 
GAGCCAGATG AAGAGTCACA CACACCTCTC CCCCCGCCCA TGAAGATCTT TGACAACGAC 
CCCACCCAGG ATGAGATGTC CTCTTTGCTA GCAGCCCGGC AGGCTCCCAC TGACGTGCCT 
ACTGCTGCAG ACCTTGTCAG TGCAATAGAA AAGTTGGTCA AAAGTAAGCT GACTCTGGAA 
GGAGGCTCTT ACCGGGGGAG CTTGAAGGAC CCTACAGTCT GCCTGAATGA GGGGATGGCC 
CCTCCCACAC CTCCTAGAAA CCTGGAAGAA GAACAGAAAG CCAAGGCTCT AAGAGGCAGG 
ATGTTTGTCC TGAATGAGTT GGTGCAGACA GAGAAGGACT ACGTCAAGGA CCTGGGGATT 
GTGGTGGAGG GCTTCATGAA AAGAATAGAA GAGAAGGGGG TCCCCGAGGA CATGCGAGGG 
AAGGAAAAGA TCGTGTTTGG AAACATCCAC CAGATTTACG ACTGGCATAA AGATTTTTTC 
CTGGCTGAAC TGGAAAAATG CATCCAAGAG CAAGACAGAT TGGCCCAGCT CTTCATTAAA 
CATGAGCGGA AGCTGCACAT CTATGTGTGG TACTGCCAGA ACAAACCACG TTCCGAATAC 
ATCGTGGCTG AATATGATGC CTACTTTGAG GAGGTTAAAC AAGAGATCAA TCAAAGGCTG 
ACCCTTAGTG ACTTCCTCAT CAAGCCCATT CAGAGAATAA CAAAGTACCA GCTGCTACTC 
AAGGACTTCC TGCGGTACAG CGAGAAGGCT GGTTTGGAGT GTTCTGATAT TGAGAAAGCA 
GTGGAGTTAA TGTGCCTTGT CCCCAAGCGC TGTAATGACA TGATGAATCT GGGACGCCTG 
CAGGGCTTTG AGGGCACCCT GACCGCCCAG GGCAAGCTTC TACAGCAGGA CACGTTCTAT 
GTGATTGAGC TGGATGCTGG CATGCAGTCC CGGACCAAGG AGAGGCGTGT GTTTCTCTTT 
GAGCAGATTG TCATCTTTAG TGAACTGCTC CGAAAGGGAT CCCTCACCCC AGGCTACATG 
TTCAAGAGGA GCATCAAGAT GAATTACTTG GTTCTGGAAG AAGATGTGGA TGATGACCCC 
TGCAAATTTG CACTTATGAA CAGGGAGACT TCAGAAAGGG TCATTCTGCA GGCCGCCAAC 
TCAGACATCC AGCAGGCCTG GGTGCAGGAC ATCAACCAAG TCCTAGAAAC ACAGAGGGAC 
TTCTTAAATG CTCTGCAGTC ACCCATCGAG TATCAGCGGA AGGAGAGGAG CACAGCTGTG 
ATCCGGTCCC AGCCCCCTAG GGTTCCTCAA GCCAGCCCCA GGCCCTATTC GTCTGTCCCA 
GTGGGCTCAG AGAAACCCCC CAAGGGCTCC AGCTACAACC CGCCCCTGCC ACCCCTGAAA 
ATATCTACCT CGAATGGCAG TCCAGGGTTC GACTACCACC AGCCTGGGGA CAAGTTTGAC 
GCTAGCAAGC AGAACGACCT GGGAGGCTGC AATGGGACCT CAACCATGGC CGTAATTAAA 
GATTACTATG CACTGAAGGA GAACGAAATC TGTGTGAGCC AAGGTGAGGT GGTCCAGGTC 
CTCGCCGTCA ACCAGCAGAA CATGTGTCTG GTGTACCAGC CTGCCAGCGA CCATTCCCCA 
GCAGCGGAGG GCTGGGTCCC AGGCAGCATC CTGGCACCCC TCACCAAAGC CACAGCGCCG 
GCCGAGAGTA GTGATGAGAG CATCAAGAAG TCATGCTCAT GGCACACTCT ACGCATGAGA 
AAGCGGGCAG ACGTGGAGAA CACGGGTAAA AATGAAGCCA CAGGGCCTCG TAAACCCAAG 
GATATTCTGG GCAACAAAGC CTCTGTTAAA GAGACGAACA GTTCCGAGGA GTCAGAGTGT 
GATGATCTTG ACCCTAATAC TAGTATGGAG ATCTTGAATC CGAATTTCAT CCAGGAAGTG 
GCTCCGGAAT TCCTTGTGCC CTTGGTAGAT GTGACCTGCT TGCTCGGAGA CACAGTACTG 
CTACAGTGCA AAGCCTGTGG GCGGCCAAAG CCTACCATCA CCTGGAAGGG TCCAGATCAG 
AACATCCTAG ACACCGACAA CAGTTCAGCC ACATACACCA TCTCCTCCTG TGATTCTGGG 
GAAAGCACCC TCAAGATCTG CAACCTGATG CCCCAAGACA GCGGGATTTA TACCTGCATA 
GCAACAAATG ACCACGGAAC CGCATCCACG TCTGCTACAG TTAAGGTGCA AGGTGTACCC 
GCAGCCCCCA ATCGCCCAAT CGCACAGGAG AGGAGCTGCA CCTCCGTCAT CCTCCGCTGG 
CTGCCCCCAG CCAGCACCGG AAACTGCACT ATTTCGGGGT ACACAGTGGA GTACCGCGAG 
GAAGGTTCGC AGGTCTGGCA GCAGTCGGTA GCTTCAACCT TGGACACTTA CCTAGTCATT 
GAAGATCTTA GTCCAGGGTG CCCTTATCAG TTCAGGGTCA GCGCCAGCAA CCCCTGGGGA 
ATCAGCCTTC CCAGTGAGCC CTCGGAGTTT GTGCACCTTC CAGAGTACGA TGCAGCTGCT 
GATGGTGCCA CCATTTCTTG GAAGGAAAAT TTTGATTCTG CTTACACCGA ACTGAACGAG 
ATTGGCAGAG GCCGTTTCTC TATTGTAAAG AAATGCATTC ACAAAGCTAC CCGCAAAGAC 
GTTGCTGTGA AATTTGTGAG CAAGAAAATG AAAAAGAAGG AACAGGCTGC GCACGAGGCC 
GCCCTGCTCC AGCACCTGCA GCACCCCCAG TACGTCACCC TCCACGACAC CTACGAGTCC 
CCCACATCCT ACATCCTGAT TTTGGAACTG ATGGATGACG GCCGACTCTT GGACTACCTA 
ATGAATCACG ATGAGCTGAT GGAAGAAAAG GTAGCTTTCT ACATTCGAGA CATCATGGAA 
GCTCTGCAGT ACCTTCACAA CTGCAGGGTG GCACATTTGG ACATAAAGCC TGAAAACCTC 
CTCATTGACC TCCGGATCCC AGTGCCTCGA GTGAAACTCA TCGACTTGGA AGATGCTGTC 
CAGATCTCAG GCCACTTCCA CATCCACCAT CTGCTGGGGA ACCCTGAGTT TGCTGCCCCG 
GAAGTGATCC AAGGCATCCC TGTCTCCCTG GGCACAGACA TCTGGAGCAT CGGGGTTCTG 
ACCTACGTCA TGCTTAGCGG GGTCTCCCCC TTCTTAGATG AGAGCAAAGA GGAGACCTGC 
ATCAACGTGT GCAGGGTGGA CTTCAGCTTC CCCCACGAAT ACTTCTGCGG TGTAAGCAAT 
GCTGCCAGGG ACTTCATCAA CGTCATCTTA CAGGAAGACT TCCGGAGGCG GCCCACAGCA 
GCCACGTGCC TGCAGCATCC GTGGCTGCAG CCCCACAACG GCAGCTACTC CAAGATCCCC 
TTGGATACCT CCCGCCTGGC CTGCTTCATA GAGCGCCGCA AGCACCAGAA TGACGTGCGG 
CCCATTCCCA ATGTCAAAAG TTACATCGTC AACAGGGTGA ACCAGGGGAC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Brain Region and Isoform-Specific Phosphorylation Alters Kalirin SH2 Domain Interaction Sites and Calpain Sensitivity.
ACS chemical neuroscience8(7)1554-1569(2017 Jul)
Miller MB,Yan Y,Machida K,Kiraly DD,Levy AD,Wu YI,Lam TT,Abbott T,Koleske AJ,Eipper BA,Mains RE

Kalirin, a GEF for Rac1, plays an important role in FSTL-1-mediated glucose uptake in skeletal muscle cells.
Cellular signalling29150-157(2017 Jan)
Lee HJ,Lee JO,Lee YW,Kim SA,Park SH,Kim HS

Orbitofrontal cortex 5-HT2A receptor mediates chronic stress-induced depressive-like behaviors and alterations of spine density and Kalirin7.
Neuropharmacology1097-17(2016 Oct)
Xu C,Ma XM,Chen HB,Zhou MH,Qiao H,An SC

Neurexin-Neuroligin Synaptic Complex Regulates Schizophrenia-Related DISC1/Kal-7/Rac1 "Signalosome".
Neural plasticity2015167308(2015)
Owczarek S,Bang ML,Berezin V

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Kalrn cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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