Gipc1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Gipc1
Entrez Gene ID	83823
Full Name	GIPC PDZ domain containing family, member 1
Synonyms	Gipc,Rgs19,Rgs19ip1
General protein information	Preferred Names GIPC PDZ domain containing family, member 1 Names PDZ domain-containing protein GIPC1 GAIP C-terminus-interacting protein GLUT1 C-terminal-binding protein GLUT1CBP RGS-GAIP interacting protein, C-terminus RGS-GAIP-interacting protein RGS19-interacting protein 1 regulator of G-protein signaling 19 interacting protein 1 synectin
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 19 Map Location: 19q11
Summary	involved in linking RGS (regulator of G-protein signaling) proteins to protein degradation [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_017601372.1	XP_017456861.1	PDZ domain-containing protein GIPC1 isoform X2
XM_006255311.3	XP_006255373.1	PDZ domain-containing protein GIPC1 isoform X1
NM_053341.1	NP_445793.1	PDZ domain-containing protein GIPC1

Pathways from BioSystems

Homologies

Caenorhabditis elegans (roundworm)	gipc-1	NP_498017.1
Homo sapiens (human)	GIPC1	NP_974199.1
Rattus norvegicus (Norway rat)	Gipc1	NP_445793.1
Pan troglodytes (chimpanzee)	GIPC1	XP_001157869.2
Bos taurus (cattle)	GIPC1	NP_001179947.1
Mus musculus (house mouse)	Gipc1	NP_061241.1
Danio rerio (zebrafish)	gipc1	NP_001004018.1
Canis lupus familiaris (dog)	GIPC1	XP_005632843.1
Caenorhabditis elegans (roundworm)	gipc-2	NP_501810.2
Xenopus tropicalis (tropical clawed frog)	gipc2	NP_001120269.1

Gene Ontology
Bibliography

Related articles in PubMed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.
Guo Z, Neilson LJ, Zhong H, Murray PS, Zanivan S, Zaidel-Bar R
Science signaling7(354)rs7(2014 Dec)

Interactions between GIPC-APPL and GIPC-TRP1 regulate melanosomal protein trafficking and melanogenesis in human melanocytes.
Kedlaya R, Kandala G, Liu TF, Maddodi N, Devi S, Setaluri V
Archives of biochemistry and biophysics508(2)227-33(2011 Apr)

Defining the membrane proteome of NK cells.
Ghosh D, Lippert D, Krokhin O, Cortens JP, Wilkins JA
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)

A novel mechanism for regulating transforming growth factor beta (TGF-beta) signaling. Functional modulation of type III TGF-beta receptor expression through interaction with the PDZ domain protein, GIPC.
Blobe GC, Liu X, Fang SJ, How T, Lodish HF
The Journal of biological chemistry276(43)39608-17(2001 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Fibroblast growth factor 2-induced Rac1 activation depends on the suppression of RhoG by a previously uncharacterized ternary S4-synectin-RhoGDI1 protein complex and activation via PKCalpha.
Title: Suppression of RhoG activity is mediated by a syndecan 4-synectin-RhoGDI1 complex and is reversed by PKCalpha in a Rac1 activation pathway.

GIPC may be preferentially associated with extrasynaptic N-methyl-D-aspartate (NMDA) receptors and may play a role in the organization and trafficking of this receptor population.
Title: The role of the PDZ protein GIPC in regulating NMDA receptor trafficking.

Results define an important role for the Myo6-GIPC1 motor complex in presynaptic function and in BDNF-TrkB-mediated synaptic plasticity.
Title: BDNF-mediated neurotransmission relies upon a myosin VI motor complex.

Synectin plays a role in neural development and regeneration in association with TrkB receptor [synectin]
Title: Synectin in the nervous system: expression pattern and potential as a binding partner of neurotrophin receptors.

GIPC acts as a selective scaffold protein to assist receptor functions.
Title: Interactions of GIPC with dopamine D2, D3 but not D4 receptors define a novel mode of regulation of G protein-coupled receptors.

The following Gipc1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gipc1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa12582	NM_053341.1 Latest version!	Rattus norvegicus GIPC PDZ domain containing family, member 1 (Gipc1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa12582	XM_017601372.1 Latest version!	Rattus norvegicus GIPC PDZ domain containing family, member 1 (Gipc1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa38744	XM_006255311.3 Latest version!	Rattus norvegicus GIPC PDZ domain containing family, member 1 (Gipc1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Gipc1 ( NM_053341.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_445793.1 Rattus norvegicus GIPC PDZ domain containing family, member 1 (Gipc1), mRNA.

Price & Availability↑

CloneID	ORa12582
Clone ID Related Accession (Same CDS sequence)	XM_017601372.1 , NM_053341.1
Accession Version	NM_053341.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1002bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Rattus norvegicus(Norway rat)
Product	PDZ domain-containing protein GIPC1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF032120.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF032120.1, BC070505.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGCCACTGG GACTGGGGCG AAGGAAAAAA GCACCACCTC TGGTGGAAAA TGAGGAGGCG 
GAGCCAAGCC GGAGTGGGCT GGGCGTCGGG GAGCCCGGGC CCCTGGGTGG AAGTGGAGCA 
GGGGAATCCC AGATGGGTTT GCCCCCACCT CCTGCTTCCC TCCGGCCTCG CCTCGTGTTC 
CATACCCAGC TGGCCCACGG CAGCCCCACG GGCCGCATCG AGGGCTTCAC TAATGTCAAG 
GAGCTGTACG GCAAGATCGC TGAGGCCTTC CGACTACCGG CTGCTGAGGT GATGTTCTGT 
ACCCTCAACA CCCATAAAGT GGATATGGAC AAGCTGCTGG GGGGCCAGAT CGGGCTGGAG 
GACTTCATCT TTGCCCATGT CAAGGGGCAG CGCAAAGAGG TGGAAGTATT CAAGTCTGAG 
GATGCTCTGG GGCTCACCAT CACCGACAAC GGGGCCGGCT ATGCCTTCAT TAAGCGCATC 
AAGGAAGGCA GTGTGATTGA CCACATCCAG CTCATCAGCG TGGGTGACAT GATTGAAGCC 
ATCAACGGGC AGAGCCTGCT GGGCTGTCGG CATTATGAGG TTGCCAGGCT CCTCAAAGAG 
CTGCCCCGAG GCCGCACCTT CACCCTCAAA CTCACCGAAC CTCGGAAGGC GTTTGATATG 
ATCAGCCAGC GTTCATCAGG TGGTCACCCT GGCTCAGGCC CACAACTGGG CACTGGCCGA 
GGGACCCTCC GGCTCCGATC CCGGGGCCCT GCCACAGTGG AGGATCTGCC GTCAGCTTTT 
GAGGAAAAGG CCATTGAAAA GGTGGATGAC TTGCTAGAGA GCTACATGGG GATCAGAGAC 
ACAGAGCTGG CTGCCACGAT GGTGGAGCTG GGGAAAGACA AAAGGAACCC AGACGAACTG 
GCAGAAGCTC TGGATGAACG GCTCGGTGAC TTCGCATTCC CAGATGAATT CGTCTTTGAT 
GTCTGGGGAG CCATCGGGGA TGCCAAGGTT GGCCGCTACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_445793.1
CDS	55..1056
Translation	MPLGLGRRKKAPPLVENEEAEPSRSGLGVGEPGPLGGSGAGESQMGLPPPPASLRPRLVFHTQLAHGSPTGRIEGFTNVKELYGKIAEAFRLPAAEVMFCTLNTHKVDMDKLLGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFIKRIKEGSVIDHIQLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKAFDMISQRSSGGHPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMGIRDTELAATMVELGKDKRNPDELAEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY

Target ORF information:

RefSeq Version	NM_053341.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus GIPC PDZ domain containing family, member 1 (Gipc1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053341.1

ORF Insert Sequence:

ATGCCACTGG GACTGGGGCG AAGGAAAAAA GCACCACCTC TGGTGGAAAA TGAGGAGGCG 
GAGCCAAGCC GGAGTGGGCT GGGCGTCGGG GAGCCCGGGC CCCTGGGTGG AAGTGGAGCA 
GGGGAATCCC AGATGGGTTT GCCCCCACCT CCTGCTTCCC TCCGGCCTCG CCTCGTGTTC 
CATACCCAGC TGGCCCACGG CAGCCCCACG GGCCGCATCG AGGGCTTCAC TAATGTCAAG 
GAGCTGTACG GCAAGATCGC TGAGGCCTTC CGACTACCGG CTGCTGAGGT GATGTTCTGT 
ACCCTCAACA CCCATAAAGT GGATATGGAC AAGCTGCTGG GGGGCCAGAT CGGGCTGGAG 
GACTTCATCT TTGCCCATGT CAAGGGGCAG CGCAAAGAGG TGGAAGTATT CAAGTCTGAG 
GATGCTCTGG GGCTCACCAT CACCGACAAC GGGGCCGGCT ATGCCTTCAT TAAGCGCATC 
AAGGAAGGCA GTGTGATTGA CCACATCCAG CTCATCAGCG TGGGTGACAT GATTGAAGCC 
ATCAACGGGC AGAGCCTGCT GGGCTGTCGG CATTATGAGG TTGCCAGGCT CCTCAAAGAG 
CTGCCCCGAG GCCGCACCTT CACCCTCAAA CTCACCGAAC CTCGGAAGGC GTTTGATATG 
ATCAGCCAGC GTTCATCAGG TGGTCACCCT GGCTCAGGCC CACAACTGGG CACTGGCCGA 
GGGACCCTCC GGCTCCGATC CCGGGGCCCT GCCACAGTGG AGGATCTGCC GTCAGCTTTT 
GAGGAAAAGG CCATTGAAAA GGTGGATGAC TTGCTAGAGA GCTACATGGG GATCAGAGAC 
ACAGAGCTGG CTGCCACGAT GGTGGAGCTG GGGAAAGACA AAAGGAACCC AGACGAACTG 
GCAGAAGCTC TGGATGAACG GCTCGGTGAC TTCGCATTCC CAGATGAATT CGTCTTTGAT 
GTCTGGGGAG CCATCGGGGA TGCCAAGGTT GGCCGCTACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gipc1 ( XM_017601372.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017456861.1 Rattus norvegicus GIPC PDZ domain containing family, member 1 (Gipc1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa12582
Clone ID Related Accession (Same CDS sequence)	XM_017601372.1 , NM_053341.1
Accession Version	XM_017601372.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1002bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	PDZ domain-containing protein GIPC1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005118.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCACTGG GACTGGGGCG AAGGAAAAAA GCACCACCTC TGGTGGAAAA TGAGGAGGCG 
GAGCCAAGCC GGAGTGGGCT GGGCGTCGGG GAGCCCGGGC CCCTGGGTGG AAGTGGAGCA 
GGGGAATCCC AGATGGGTTT GCCCCCACCT CCTGCTTCCC TCCGGCCTCG CCTCGTGTTC 
CATACCCAGC TGGCCCACGG CAGCCCCACG GGCCGCATCG AGGGCTTCAC TAATGTCAAG 
GAGCTGTACG GCAAGATCGC TGAGGCCTTC CGACTACCGG CTGCTGAGGT GATGTTCTGT 
ACCCTCAACA CCCATAAAGT GGATATGGAC AAGCTGCTGG GGGGCCAGAT CGGGCTGGAG 
GACTTCATCT TTGCCCATGT CAAGGGGCAG CGCAAAGAGG TGGAAGTATT CAAGTCTGAG 
GATGCTCTGG GGCTCACCAT CACCGACAAC GGGGCCGGCT ATGCCTTCAT TAAGCGCATC 
AAGGAAGGCA GTGTGATTGA CCACATCCAG CTCATCAGCG TGGGTGACAT GATTGAAGCC 
ATCAACGGGC AGAGCCTGCT GGGCTGTCGG CATTATGAGG TTGCCAGGCT CCTCAAAGAG 
CTGCCCCGAG GCCGCACCTT CACCCTCAAA CTCACCGAAC CTCGGAAGGC GTTTGATATG 
ATCAGCCAGC GTTCATCAGG TGGTCACCCT GGCTCAGGCC CACAACTGGG CACTGGCCGA 
GGGACCCTCC GGCTCCGATC CCGGGGCCCT GCCACAGTGG AGGATCTGCC GTCAGCTTTT 
GAGGAAAAGG CCATTGAAAA GGTGGATGAC TTGCTAGAGA GCTACATGGG GATCAGAGAC 
ACAGAGCTGG CTGCCACGAT GGTGGAGCTG GGGAAAGACA AAAGGAACCC AGACGAACTG 
GCAGAAGCTC TGGATGAACG GCTCGGTGAC TTCGCATTCC CAGATGAATT CGTCTTTGAT 
GTCTGGGGAG CCATCGGGGA TGCCAAGGTT GGCCGCTACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017456861.1
CDS	244..1245
Translation	MPLGLGRRKKAPPLVENEEAEPSRSGLGVGEPGPLGGSGAGESQMGLPPPPASLRPRLVFHTQLAHGSPTGRIEGFTNVKELYGKIAEAFRLPAAEVMFCTLNTHKVDMDKLLGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFIKRIKEGSVIDHIQLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKAFDMISQRSSGGHPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMGIRDTELAATMVELGKDKRNPDELAEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY

Target ORF information:

RefSeq Version	XM_017601372.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus GIPC PDZ domain containing family, member 1 (Gipc1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017601372.1

ORF Insert Sequence:

ATGCCACTGG GACTGGGGCG AAGGAAAAAA GCACCACCTC TGGTGGAAAA TGAGGAGGCG 
GAGCCAAGCC GGAGTGGGCT GGGCGTCGGG GAGCCCGGGC CCCTGGGTGG AAGTGGAGCA 
GGGGAATCCC AGATGGGTTT GCCCCCACCT CCTGCTTCCC TCCGGCCTCG CCTCGTGTTC 
CATACCCAGC TGGCCCACGG CAGCCCCACG GGCCGCATCG AGGGCTTCAC TAATGTCAAG 
GAGCTGTACG GCAAGATCGC TGAGGCCTTC CGACTACCGG CTGCTGAGGT GATGTTCTGT 
ACCCTCAACA CCCATAAAGT GGATATGGAC AAGCTGCTGG GGGGCCAGAT CGGGCTGGAG 
GACTTCATCT TTGCCCATGT CAAGGGGCAG CGCAAAGAGG TGGAAGTATT CAAGTCTGAG 
GATGCTCTGG GGCTCACCAT CACCGACAAC GGGGCCGGCT ATGCCTTCAT TAAGCGCATC 
AAGGAAGGCA GTGTGATTGA CCACATCCAG CTCATCAGCG TGGGTGACAT GATTGAAGCC 
ATCAACGGGC AGAGCCTGCT GGGCTGTCGG CATTATGAGG TTGCCAGGCT CCTCAAAGAG 
CTGCCCCGAG GCCGCACCTT CACCCTCAAA CTCACCGAAC CTCGGAAGGC GTTTGATATG 
ATCAGCCAGC GTTCATCAGG TGGTCACCCT GGCTCAGGCC CACAACTGGG CACTGGCCGA 
GGGACCCTCC GGCTCCGATC CCGGGGCCCT GCCACAGTGG AGGATCTGCC GTCAGCTTTT 
GAGGAAAAGG CCATTGAAAA GGTGGATGAC TTGCTAGAGA GCTACATGGG GATCAGAGAC 
ACAGAGCTGG CTGCCACGAT GGTGGAGCTG GGGAAAGACA AAAGGAACCC AGACGAACTG 
GCAGAAGCTC TGGATGAACG GCTCGGTGAC TTCGCATTCC CAGATGAATT CGTCTTTGAT 
GTCTGGGGAG CCATCGGGGA TGCCAAGGTT GGCCGCTACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gipc1 ( XM_006255311.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006255373.1 Rattus norvegicus GIPC PDZ domain containing family, member 1 (Gipc1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa38744
Clone ID Related Accession (Same CDS sequence)	XM_006255311.3
Accession Version	XM_006255311.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1086bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	PDZ domain-containing protein GIPC1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005118.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006255311.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCACCCA AGGCTGGTAC TCAGAGAGTG AAGCCCGATT CCCTTTCGCA GGTCTCCCGG 
CCAAGTCCCC ACTTCTGGCT GCTCATGCCA CTGGGACTGG GGCGAAGGAA AAAAGCACCA 
CCTCTGGTGG AAAATGAGGA GGCGGAGCCA AGCCGGAGTG GGCTGGGCGT CGGGGAGCCC 
GGGCCCCTGG GTGGAAGTGG AGCAGGGGAA TCCCAGATGG GTTTGCCCCC ACCTCCTGCT 
TCCCTCCGGC CTCGCCTCGT GTTCCATACC CAGCTGGCCC ACGGCAGCCC CACGGGCCGC 
ATCGAGGGCT TCACTAATGT CAAGGAGCTG TACGGCAAGA TCGCTGAGGC CTTCCGACTA 
CCGGCTGCTG AGGTGATGTT CTGTACCCTC AACACCCATA AAGTGGATAT GGACAAGCTG 
CTGGGGGGCC AGATCGGGCT GGAGGACTTC ATCTTTGCCC ATGTCAAGGG GCAGCGCAAA 
GAGGTGGAAG TATTCAAGTC TGAGGATGCT CTGGGGCTCA CCATCACCGA CAACGGGGCC 
GGCTATGCCT TCATTAAGCG CATCAAGGAA GGCAGTGTGA TTGACCACAT CCAGCTCATC 
AGCGTGGGTG ACATGATTGA AGCCATCAAC GGGCAGAGCC TGCTGGGCTG TCGGCATTAT 
GAGGTTGCCA GGCTCCTCAA AGAGCTGCCC CGAGGCCGCA CCTTCACCCT CAAACTCACC 
GAACCTCGGA AGGCGTTTGA TATGATCAGC CAGCGTTCAT CAGGTGGTCA CCCTGGCTCA 
GGCCCACAAC TGGGCACTGG CCGAGGGACC CTCCGGCTCC GATCCCGGGG CCCTGCCACA 
GTGGAGGATC TGCCGTCAGC TTTTGAGGAA AAGGCCATTG AAAAGGTGGA TGACTTGCTA 
GAGAGCTACA TGGGGATCAG AGACACAGAG CTGGCTGCCA CGATGGTGGA GCTGGGGAAA 
GACAAAAGGA ACCCAGACGA ACTGGCAGAA GCTCTGGATG AACGGCTCGG TGACTTCGCA 
TTCCCAGATG AATTCGTCTT TGATGTCTGG GGAGCCATCG GGGATGCCAA GGTTGGCCGC 
TACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006255373.1
CDS	950..2035
Translation	MAPKAGTQRVKPDSLSQVSRPSPHFWLLMPLGLGRRKKAPPLVENEEAEPSRSGLGVGEPGPLGGSGAGESQMGLPPPPASLRPRLVFHTQLAHGSPTGRIEGFTNVKELYGKIAEAFRLPAAEVMFCTLNTHKVDMDKLLGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFIKRIKEGSVIDHIQLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKAFDMISQRSSGGHPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMGIRDTELAATMVELGKDKRNPDELAEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY

Target ORF information:

RefSeq Version	XM_006255311.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus GIPC PDZ domain containing family, member 1 (Gipc1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006255311.3

ORF Insert Sequence:

ATGGCACCCA AGGCTGGTAC TCAGAGAGTG AAGCCCGATT CCCTTTCGCA GGTCTCCCGG 
CCAAGTCCCC ACTTCTGGCT GCTCATGCCA CTGGGACTGG GGCGAAGGAA AAAAGCACCA 
CCTCTGGTGG AAAATGAGGA GGCGGAGCCA AGCCGGAGTG GGCTGGGCGT CGGGGAGCCC 
GGGCCCCTGG GTGGAAGTGG AGCAGGGGAA TCCCAGATGG GTTTGCCCCC ACCTCCTGCT 
TCCCTCCGGC CTCGCCTCGT GTTCCATACC CAGCTGGCCC ACGGCAGCCC CACGGGCCGC 
ATCGAGGGCT TCACTAATGT CAAGGAGCTG TACGGCAAGA TCGCTGAGGC CTTCCGACTA 
CCGGCTGCTG AGGTGATGTT CTGTACCCTC AACACCCATA AAGTGGATAT GGACAAGCTG 
CTGGGGGGCC AGATCGGGCT GGAGGACTTC ATCTTTGCCC ATGTCAAGGG GCAGCGCAAA 
GAGGTGGAAG TATTCAAGTC TGAGGATGCT CTGGGGCTCA CCATCACCGA CAACGGGGCC 
GGCTATGCCT TCATTAAGCG CATCAAGGAA GGCAGTGTGA TTGACCACAT CCAGCTCATC 
AGCGTGGGTG ACATGATTGA AGCCATCAAC GGGCAGAGCC TGCTGGGCTG TCGGCATTAT 
GAGGTTGCCA GGCTCCTCAA AGAGCTGCCC CGAGGCCGCA CCTTCACCCT CAAACTCACC 
GAACCTCGGA AGGCGTTTGA TATGATCAGC CAGCGTTCAT CAGGTGGTCA CCCTGGCTCA 
GGCCCACAAC TGGGCACTGG CCGAGGGACC CTCCGGCTCC GATCCCGGGG CCCTGCCACA 
GTGGAGGATC TGCCGTCAGC TTTTGAGGAA AAGGCCATTG AAAAGGTGGA TGACTTGCTA 
GAGAGCTACA TGGGGATCAG AGACACAGAG CTGGCTGCCA CGATGGTGGA GCTGGGGAAA 
GACAAAAGGA ACCCAGACGA ACTGGCAGAA GCTCTGGATG AACGGCTCGG TGACTTCGCA 
TTCCCAGATG AATTCGTCTT TGATGTCTGG GGAGCCATCG GGGATGCCAA GGTTGGCCGC 
TACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.
Science signaling7(354)rs7(2014 Dec)
Guo Z,Neilson LJ,Zhong H,Murray PS,Zanivan S,Zaidel-Bar R

Interactions between GIPC-APPL and GIPC-TRP1 regulate melanosomal protein trafficking and melanogenesis in human melanocytes.
Archives of biochemistry and biophysics508(2)227-33(2011 Apr)
Kedlaya R,Kandala G,Liu TF,Maddodi N,Devi S,Setaluri V

Defining the membrane proteome of NK cells.
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)
Ghosh D,Lippert D,Krokhin O,Cortens JP,Wilkins JA

A novel mechanism for regulating transforming growth factor beta (TGF-beta) signaling. Functional modulation of type III TGF-beta receptor expression through interaction with the PDZ domain protein, GIPC.
The Journal of biological chemistry276(43)39608-17(2001 Oct)
Blobe GC,Liu X,Fang SJ,How T,Lodish HF

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Gipc1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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