Rtn4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Rtn4
Entrez Gene ID	83765
Full Name	reticulon 4
Synonyms	NI-250,Nogo,Nogo-A,Vp20,r,rat N,rat NogoA
General protein information	Preferred Names reticulon 4 Names reticulon-4 GLUT4 vesicle 20kDa protein NI-220/250 foocen glut4 vesicle 20 kDa protein neurite outgrowth inhibitor nogo protein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 14 Map Location: 14q22
Summary	a myelin protein that is a potent inhibitor of neurite growth [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_017599393.1	XP_017454882.1	reticulon-4 isoform X2
XM_006251608.2	XP_006251670.2	reticulon-4 isoform X3
XM_006251609.3	XP_006251671.1	reticulon-4 isoform X4
XM_006251605.3	XP_006251667.2	reticulon-4 isoform X1
NM_031831.1	NP_114019.1	reticulon-4

Pathways from BioSystems

Homologies

Homo sapiens (human)	RTN4	NP_065393.1
	RTN4	XP_001112090.2
Canis lupus familiaris (dog)	RTN4	XP_531828.2
Xenopus tropicalis (tropical clawed frog)	rtn4	NP_001161159.1
Bos taurus (cattle)	RTN4	NP_001106692.1
Rattus norvegicus (Norway rat)	Rtn4	NP_114019.1
Mus musculus (house mouse)	Rtn4	NP_918943.1
Gallus gallus (chicken)	LOC101749579	XP_004940228.1

Gene Ontology
Bibliography

Related articles in PubMed

Nogo-A interacts with TrkA to alter nerve growth factor signaling in Nogo-A-overexpressing PC12 cells.
Farrer RG, Kartje GL
Cellular signalling4420-27(2018 Jan)

Towards Functional Annotation of the Preimplantation Transcriptome: An RNAi Screen in Mammalian Embryos.
Cui W, Dai X, Marcho C, Han Z, Zhang K, Tremblay KD, Mager J
Scientific reports637396(2016 Nov)

Nogo-C regulates cardiomyocyte apoptosis during mouse myocardial infarction.
Jia S, Qiao X, Ye J, Fang X, Xu C, Cao Y, Zheng M
Cell death & disease7(10)e2432(2016 Oct)

NOGO-A/RTN4A and NOGO-B/RTN4B are simultaneously expressed in epithelial, fibroblast and neuronal cells and maintain ER morphology.
R?m? O, Kumar D, Gucciardo E, Joensuu M, Saarekas M, Vihinen H, Belevich I, Smolander OP, Qian K, Auvinen P, Jokitalo E
Scientific reports635969(2016 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Nogo-A signaling in the adult nervous system modulates the spine actin cytoskeleton within minutes to control structural plasticity at dendritic spines of CA3 pyramidal neurons. Acute Nogo-A loss-of-function transiently increases F-actin stability and results in an increase in dendritic spine density and length. Nogo-A acutely restricts AMPAR insertion and membrane potential amplitude at hippocampal synaptic sites.
Title: Nogo-A controls structural plasticity at dendritic spines by rapidly modulating actin dynamics.

the combined delivery of NT-3 and anti-NogoA from the DDS in an impact/compression model of SCI increases axon density and improves locomotor function.
Title: Local Delivery of Neurotrophin-3 and Anti-NogoA Promotes Repair After Spinal Cord Injury.

Nogo-A shRNA interference can knockdown Nogo gene expression and upregulate GAP-43 to promote the functional recovery of spinal cord injury in rats. This finding may advance progress toward assisting the regeneration of injured neurons through the use of Nogo-A shRNA.
Title: Knockdown of Nogo gene by short hairpin RNA interference promotes functional recovery of spinal cord injury in a rat model.

The observation of upregulated Nogo-A/NgR in lesion sites in the neonatal cortex freeze-lesion model suggest that the effects of the perturbed Nogo-A are a key feature during the development and/or the progression of cortical malformation.
Title: Upregulated expression of Nogo-A and NgR in an experimental model of focal microgyria regulates the migration, proliferation and self-renewal of subventricular zone neural progenitors.

Data suggest that adipose-derived stem cells (ADSCs) transplantation could promote the recovery of neurological functions, partly by inhibiting the expression of neurite outgrowth inhibitor-A (Nogo-A) in middle cerebral artery occlusion (MCAO) brain.
Title: [Adipose-derived stem cell transplantation inhibits the expression of Nogo-A in the perilesional cortex of rats with focal cerebral ischemia].

The following Rtn4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rtn4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa36479	XM_006251609.3 Latest version!	Rattus norvegicus reticulon 4 (Rtn4), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa08834	NM_031831.1 Latest version!	Rattus norvegicus reticulon 4 (Rtn4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$853.30 $1219.00
ORa58434	XM_006251605.3 Latest version!	Rattus norvegicus reticulon 4 (Rtn4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$559.30 $799.00
ORa58435	XM_017599393.1 Latest version!	Rattus norvegicus reticulon 4 (Rtn4), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
ORa58436	XM_006251608.2 Latest version!	Rattus norvegicus reticulon 4 (Rtn4), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Rtn4 ( XM_006251609.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006251671.1 Rattus norvegicus reticulon 4 (Rtn4), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa36479
Clone ID Related Accession (Same CDS sequence)	XM_006251609.3
Accession Version	XM_006251609.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 600bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	reticulon-4 isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005113.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006251609.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACGGAC AGAAGAAACA TTGGAAGGAC AAGGTTGTTG ACCTCCTCTA CTGGAGAGAC 
ATTAAGAAGA CTGGAGTGGT GTTTGGTGCC AGCTTATTCC TGCTGCTGTC TCTGACAGTG 
TTCAGCATTG TCAGTGTAAC GGCCTACATT GCCTTGGCCC TGCTCTCGGT GACTATCAGC 
TTTAGGATAT ATAAGGGCGT GATCCAGGCT ATCCAGAAAT CAGATGAAGG CCACCCATTC 
AGGGCATATT TAGAATCTGA AGTTGCTATA TCAGAGGAAT TGGTTCAGAA ATACAGTAAT 
TCTGCTCTTG GTCATGTGAA CAGCACAATA AAAGAACTGA GGCGGCTTTT CTTAGTTGAT 
GATTTAGTTG ATTCCCTGAA GTTTGCAGTG TTGATGTGGG TGTTTACTTA TGTTGGTGCC 
TTGTTCAATG GTCTGACACT ACTGATTTTA GCTCTGATCT CACTCTTCAG TATTCCTGTT 
ATTTATGAAC GGCATCAGGT GCAGATAGAT CATTATCTAG GACTTGCAAA CAAGAGTGTT 
AAGGATGCCA TGGCCAAAAT CCAAGCAAAA ATCCCTGGAT TGAAGCGCAA AGCAGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006251671.1
CDS	614..1213
Translation	MDGQKKHWKDKVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNSTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSIPVIYERHQVQIDHYLGLANKSVKDAMAKIQAKIPGLKRKAD

Target ORF information:

RefSeq Version	XM_006251609.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus reticulon 4 (Rtn4), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006251609.3

ORF Insert Sequence:

ATGGACGGAC AGAAGAAACA TTGGAAGGAC AAGGTTGTTG ACCTCCTCTA CTGGAGAGAC 
ATTAAGAAGA CTGGAGTGGT GTTTGGTGCC AGCTTATTCC TGCTGCTGTC TCTGACAGTG 
TTCAGCATTG TCAGTGTAAC GGCCTACATT GCCTTGGCCC TGCTCTCGGT GACTATCAGC 
TTTAGGATAT ATAAGGGCGT GATCCAGGCT ATCCAGAAAT CAGATGAAGG CCACCCATTC 
AGGGCATATT TAGAATCTGA AGTTGCTATA TCAGAGGAAT TGGTTCAGAA ATACAGTAAT 
TCTGCTCTTG GTCATGTGAA CAGCACAATA AAAGAACTGA GGCGGCTTTT CTTAGTTGAT 
GATTTAGTTG ATTCCCTGAA GTTTGCAGTG TTGATGTGGG TGTTTACTTA TGTTGGTGCC 
TTGTTCAATG GTCTGACACT ACTGATTTTA GCTCTGATCT CACTCTTCAG TATTCCTGTT 
ATTTATGAAC GGCATCAGGT GCAGATAGAT CATTATCTAG GACTTGCAAA CAAGAGTGTT 
AAGGATGCCA TGGCCAAAAT CCAAGCAAAA ATCCCTGGAT TGAAGCGCAA AGCAGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rtn4 ( NM_031831.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_114019.1 Rattus norvegicus reticulon 4 (Rtn4), mRNA.

Price & Availability↑

CloneID	ORa08834
Clone ID Related Accession (Same CDS sequence)	NM_031831.1
Accession Version	NM_031831.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3492bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-15
Organism	Rattus norvegicus(Norway rat)
Product	reticulon-4
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ242961.1. On Jun 25, 2006 this sequence version replaced XM_001065481.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ242961.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGAAGACA TAGACCAGTC GTCGCTGGTC TCCTCGTCCA CGGACAGCCC GCCCCGGCCT 
CCGCCCGCCT TCAAGTACCA GTTCGTGACG GAGCCCGAGG ACGAGGAGGA CGAGGAGGAG 
GAGGAGGACG AGGAGGAGGA CGACGAGGAC CTAGAGGAAC TGGAGGTGCT GGAGAGGAAG 
CCCGCAGCCG GGCTGTCCGC AGCTGCGGTG CCGCCCGCCG CCGCCGCGCC GCTGCTGGAC 
TTCAGCAGCG ACTCGGTGCC CCCCGCGCCC CGCGGGCCGC TGCCGGCCGC GCCCCCTGCC 
GCTCCTGAGA GGCAGCCATC CTGGGAACGC AGCCCCGCGG CGCCCGCGCC ATCCCTGCCG 
CCCGCTGCCG CAGTCCTGCC CTCCAAGCTC CCAGAGGACG ACGAGCCTCC GGCGAGGCCC 
CCGCCTCCGC CGCCAGCCGG CGCGAGCCCC CTGGCGGAGC CCGCCGCGCC CCCTTCCACG 
CCGGCCGCGC CCAAGCGCAG GGGCTCCGGC TCAGTGGATG AGACCCTTTT TGCTCTTCCT 
GCTGCATCTG AGCCTGTGAT ACCCTCCTCT GCAGAAAAAA TTATGGATTT GATGGAGCAG 
CCAGGTAACA CTGTTTCGTC TGGTCAAGAG GATTTCCCAT CTGTCCTGCT TGAAACTGCT 
GCCTCTCTTC CTTCTCTATC TCCTCTCTCA ACTGTTTCTT TTAAAGAACA TGGATACCTT 
GGTAACTTAT CAGCAGTGTC ATCCTCAGAA GGAACAATTG AAGAAACTTT AAATGAAGCT 
TCTAAAGAGT TGCCAGAGAG GGCAACAAAT CCATTTGTAA ATAGAGATTT AGCAGAATTT 
TCAGAATTAG AATATTCAGA AATGGGATCA TCTTTTAAAG GCTCCCCAAA AGGAGAGTCA 
GCCATATTAG TAGAAAACAC TAAGGAAGAA GTAATTGTGA GGAGTAAAGA CAAAGAGGAT 
TTAGTTTGTA GTGCAGCCCT TCACAGTCCA CAAGAATCAC CTGTGGGTAA AGAAGACAGA 
GTTGTGTCTC CAGAAAAGAC AATGGACATT TTTAATGAAA TGCAGATGTC AGTAGTAGCA 
CCTGTGAGGG AAGAGTATGC AGACTTTAAG CCATTTGAAC AAGCATGGGA AGTGAAAGAT 
ACTTATGAGG GAAGTAGGGA TGTGCTGGCT GCTAGAGCTA ATGTGGAAAG TAAAGTGGAC 
AGAAAATGCT TGGAAGATAG CCTGGAGCAA AAAAGTCTTG GGAAGGATAG TGAAGGCAGA 
AATGAGGATG CTTCTTTCCC CAGTACCCCA GAACCTGTGA AGGACAGCTC CAGAGCATAT 
ATTACCTGTG CTTCCTTTAC CTCAGCAACC GAAAGCACCA CAGCAAACAC TTTCCCTTTG 
TTAGAAGATC ATACTTCAGA AAATAAAACA GATGAAAAAA AAATAGAAGA AAGGAAGGCC 
CAAATTATAA CAGAGAAGAC TAGCCCCAAA ACGTCAAATC CTTTCCTTGT AGCAGTACAG 
GATTCTGAGG CAGATTATGT TACAACAGAT ACCTTATCAA AGGTGACTGA GGCAGCAGTG 
TCAAACATGC CTGAAGGTCT GACGCCAGAT TTAGTTCAGG AAGCATGTGA AAGTGAACTG 
AATGAAGCCA CAGGTACAAA GATTGCTTAT GAAACAAAAG TGGACTTGGT CCAAACATCA 
GAAGCTATAC AAGAATCACT TTACCCCACA GCACAGCTTT GCCCATCATT TGAGGAAGCT 
GAAGCAACTC CGTCACCAGT TTTGCCTGAT ATTGTTATGG AAGCACCATT AAATTCTCTC 
CTTCCAAGCG CTGGTGCTTC TGTAGTGCAG CCCAGTGTAT CCCCACTGGA AGCACCTCCT 
CCAGTTAGTT ATGACAGTAT AAAGCTTGAG CCTGAAAACC CCCCACCATA TGAAGAAGCC 
ATGAATGTAG CACTAAAAGC TTTGGGAACA AAGGAAGGAA TAAAAGAGCC TGAAAGTTTT 
AATGCAGCTG TTCAGGAAAC AGAAGCTCCT TATATATCCA TTGCGTGTGA TTTAATTAAA 
GAAACAAAGC TCTCCACTGA GCCAAGTCCA GATTTCTCTA ATTATTCAGA AATAGCAAAA 
TTCGAGAAGT CGGTGCCCGA ACACGCTGAG CTAGTGGAGG ATTCCTCACC TGAATCTGAA 
CCAGTTGACT TATTTAGTGA TGATTCGATT CCTGAAGTCC CACAAACACA AGAGGAGGCT 
GTGATGCTCA TGAAGGAGAG TCTCACTGAA GTGTCTGAGA CAGTAGCCCA GCACAAAGAG 
GAGAGACTTA GTGCCTCACC TCAGGAGCTA GGAAAGCCAT ATTTAGAGTC TTTTCAGCCC 
AATTTACATA GTACAAAAGA TGCTGCATCT AATGACATTC CAACATTGAC CAAAAAGGAG 
AAAATTTCTT TGCAAATGGA AGAGTTTAAT ACTGCAATTT ATTCAAATGA TGACTTACTT 
TCTTCTAAGG AAGACAAAAT AAAAGAAAGT GAAACATTTT CAGATTCATC TCCGATTGAG 
ATAATAGATG AATTTCCCAC GTTTGTCAGT GCTAAAGATG ATTCTCCTAA ATTAGCCAAG 
GAGTACACTG ATCTAGAAGT ATCCGACAAA AGTGAAATTG CTAATATCCA AAGCGGGGCA 
GATTCATTGC CTTGCTTAGA ATTGCCCTGT GACCTTTCTT TCAAGAATAT ATATCCTAAA 
GATGAAGTAC ATGTTTCAGA TGAATTCTCC GAAAATAGGT CCAGTGTATC TAAGGCATCC 
ATATCGCCTT CAAATGTCTC TGCTTTGGAA CCTCAGACAG AAATGGGCAG CATAGTTAAA 
TCCAAATCAC TTACGAAAGA AGCAGAGAAA AAACTTCCTT CTGACACAGA GAAAGAGGAC 
AGATCCCTGT CAGCTGTATT GTCAGCAGAG CTGAGTAAAA CTTCAGTTGT TGACCTCCTC 
TACTGGAGAG ACATTAAGAA GACTGGAGTG GTGTTTGGTG CCAGCTTATT CCTGCTGCTG 
TCTCTGACAG TGTTCAGCAT TGTCAGTGTA ACGGCCTACA TTGCCTTGGC CCTGCTCTCG 
GTGACTATCA GCTTTAGGAT ATATAAGGGC GTGATCCAGG CTATCCAGAA ATCAGATGAA 
GGCCACCCAT TCAGGGCATA TTTAGAATCT GAAGTTGCTA TATCAGAGGA ATTGGTTCAG 
AAATACAGTA ATTCTGCTCT TGGTCATGTG AACAGCACAA TAAAAGAACT GAGGCGGCTT 
TTCTTAGTTG ATGATTTAGT TGATTCCCTG AAGTTTGCAG TGTTGATGTG GGTGTTTACT 
TATGTTGGTG CCTTGTTCAA TGGTCTGACA CTACTGATTT TAGCTCTGAT CTCACTCTTC 
AGTATTCCTG TTATTTATGA ACGGCATCAG GTGCAGATAG ATCATTATCT AGGACTTGCA 
AACAAGAGTG TTAAGGATGC CATGGCCAAA ATCCAAGCAA AAATCCCTGG ATTGAAGCGC 
AAAGCAGATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_114019.1
CDS	253..3744
Translation	MEDIDQSSLVSSSTDSPPRPPPAFKYQFVTEPEDEEDEEEEEDEEEDDEDLEELEVLERKPAAGLSAAAVPPAAAAPLLDFSSDSVPPAPRGPLPAAPPAAPERQPSWERSPAAPAPSLPPAAAVLPSKLPEDDEPPARPPPPPPAGASPLAEPAAPPSTPAAPKRRGSGSVDETLFALPAASEPVIPSSAEKIMDLMEQPGNTVSSGQEDFPSVLLETAASLPSLSPLSTVSFKEHGYLGNLSAVSSSEGTIEETLNEASKELPERATNPFVNRDLAEFSELEYSEMGSSFKGSPKGESAILVENTKEEVIVRSKDKEDLVCSAALHSPQESPVGKEDRVVSPEKTMDIFNEMQMSVVAPVREEYADFKPFEQAWEVKDTYEGSRDVLAARANVESKVDRKCLEDSLEQKSLGKDSEGRNEDASFPSTPEPVKDSSRAYITCASFTSATESTTANTFPLLEDHTSENKTDEKKIEERKAQIITEKTSPKTSNPFLVAVQDSEADYVTTDTLSKVTEAAVSNMPEGLTPDLVQEACESELNEATGTKIAYETKVDLVQTSEAIQESLYPTAQLCPSFEEAEATPSPVLPDIVMEAPLNSLLPSAGASVVQPSVSPLEAPPPVSYDSIKLEPENPPPYEEAMNVALKALGTKEGIKEPESFNAAVQETEAPYISIACDLIKETKLSTEPSPDFSNYSEIAKFEKSVPEHAELVEDSSPESEPVDLFSDDSIPEVPQTQEEAVMLMKESLTEVSETVAQHKEERLSASPQELGKPYLESFQPNLHSTKDAASNDIPTLTKKEKISLQMEEFNTAIYSNDDLLSSKEDKIKESETFSDSSPIEIIDEFPTFVSAKDDSPKLAKEYTDLEVSDKSEIANIQSGADSLPCLELPCDLSFKNIYPKDEVHVSDEFSENRSSVSKASISPSNVSALEPQTEMGSIVKSKSLTKEAEKKLPSDTEKEDRSLSAVLSAELSKTSVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNSTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSIPVIYERHQVQIDHYLGLANKSVKDAMAKIQAKIPGLKRKAD

Target ORF information:

RefSeq Version	NM_031831.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus reticulon 4 (Rtn4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031831.1

ORF Insert Sequence:

ATGGAAGACA TAGACCAGTC GTCGCTGGTC TCCTCGTCCA CGGACAGCCC GCCCCGGCCT 
CCGCCCGCCT TCAAGTACCA GTTCGTGACG GAGCCCGAGG ACGAGGAGGA CGAGGAGGAG 
GAGGAGGACG AGGAGGAGGA CGACGAGGAC CTAGAGGAAC TGGAGGTGCT GGAGAGGAAG 
CCCGCAGCCG GGCTGTCCGC AGCTGCGGTG CCGCCCGCCG CCGCCGCGCC GCTGCTGGAC 
TTCAGCAGCG ACTCGGTGCC CCCCGCGCCC CGCGGGCCGC TGCCGGCCGC GCCCCCTGCC 
GCTCCTGAGA GGCAGCCATC CTGGGAACGC AGCCCCGCGG CGCCCGCGCC ATCCCTGCCG 
CCCGCTGCCG CAGTCCTGCC CTCCAAGCTC CCAGAGGACG ACGAGCCTCC GGCGAGGCCC 
CCGCCTCCGC CGCCAGCCGG CGCGAGCCCC CTGGCGGAGC CCGCCGCGCC CCCTTCCACG 
CCGGCCGCGC CCAAGCGCAG GGGCTCCGGC TCAGTGGATG AGACCCTTTT TGCTCTTCCT 
GCTGCATCTG AGCCTGTGAT ACCCTCCTCT GCAGAAAAAA TTATGGATTT GATGGAGCAG 
CCAGGTAACA CTGTTTCGTC TGGTCAAGAG GATTTCCCAT CTGTCCTGCT TGAAACTGCT 
GCCTCTCTTC CTTCTCTATC TCCTCTCTCA ACTGTTTCTT TTAAAGAACA TGGATACCTT 
GGTAACTTAT CAGCAGTGTC ATCCTCAGAA GGAACAATTG AAGAAACTTT AAATGAAGCT 
TCTAAAGAGT TGCCAGAGAG GGCAACAAAT CCATTTGTAA ATAGAGATTT AGCAGAATTT 
TCAGAATTAG AATATTCAGA AATGGGATCA TCTTTTAAAG GCTCCCCAAA AGGAGAGTCA 
GCCATATTAG TAGAAAACAC TAAGGAAGAA GTAATTGTGA GGAGTAAAGA CAAAGAGGAT 
TTAGTTTGTA GTGCAGCCCT TCACAGTCCA CAAGAATCAC CTGTGGGTAA AGAAGACAGA 
GTTGTGTCTC CAGAAAAGAC AATGGACATT TTTAATGAAA TGCAGATGTC AGTAGTAGCA 
CCTGTGAGGG AAGAGTATGC AGACTTTAAG CCATTTGAAC AAGCATGGGA AGTGAAAGAT 
ACTTATGAGG GAAGTAGGGA TGTGCTGGCT GCTAGAGCTA ATGTGGAAAG TAAAGTGGAC 
AGAAAATGCT TGGAAGATAG CCTGGAGCAA AAAAGTCTTG GGAAGGATAG TGAAGGCAGA 
AATGAGGATG CTTCTTTCCC CAGTACCCCA GAACCTGTGA AGGACAGCTC CAGAGCATAT 
ATTACCTGTG CTTCCTTTAC CTCAGCAACC GAAAGCACCA CAGCAAACAC TTTCCCTTTG 
TTAGAAGATC ATACTTCAGA AAATAAAACA GATGAAAAAA AAATAGAAGA AAGGAAGGCC 
CAAATTATAA CAGAGAAGAC TAGCCCCAAA ACGTCAAATC CTTTCCTTGT AGCAGTACAG 
GATTCTGAGG CAGATTATGT TACAACAGAT ACCTTATCAA AGGTGACTGA GGCAGCAGTG 
TCAAACATGC CTGAAGGTCT GACGCCAGAT TTAGTTCAGG AAGCATGTGA AAGTGAACTG 
AATGAAGCCA CAGGTACAAA GATTGCTTAT GAAACAAAAG TGGACTTGGT CCAAACATCA 
GAAGCTATAC AAGAATCACT TTACCCCACA GCACAGCTTT GCCCATCATT TGAGGAAGCT 
GAAGCAACTC CGTCACCAGT TTTGCCTGAT ATTGTTATGG AAGCACCATT AAATTCTCTC 
CTTCCAAGCG CTGGTGCTTC TGTAGTGCAG CCCAGTGTAT CCCCACTGGA AGCACCTCCT 
CCAGTTAGTT ATGACAGTAT AAAGCTTGAG CCTGAAAACC CCCCACCATA TGAAGAAGCC 
ATGAATGTAG CACTAAAAGC TTTGGGAACA AAGGAAGGAA TAAAAGAGCC TGAAAGTTTT 
AATGCAGCTG TTCAGGAAAC AGAAGCTCCT TATATATCCA TTGCGTGTGA TTTAATTAAA 
GAAACAAAGC TCTCCACTGA GCCAAGTCCA GATTTCTCTA ATTATTCAGA AATAGCAAAA 
TTCGAGAAGT CGGTGCCCGA ACACGCTGAG CTAGTGGAGG ATTCCTCACC TGAATCTGAA 
CCAGTTGACT TATTTAGTGA TGATTCGATT CCTGAAGTCC CACAAACACA AGAGGAGGCT 
GTGATGCTCA TGAAGGAGAG TCTCACTGAA GTGTCTGAGA CAGTAGCCCA GCACAAAGAG 
GAGAGACTTA GTGCCTCACC TCAGGAGCTA GGAAAGCCAT ATTTAGAGTC TTTTCAGCCC 
AATTTACATA GTACAAAAGA TGCTGCATCT AATGACATTC CAACATTGAC CAAAAAGGAG 
AAAATTTCTT TGCAAATGGA AGAGTTTAAT ACTGCAATTT ATTCAAATGA TGACTTACTT 
TCTTCTAAGG AAGACAAAAT AAAAGAAAGT GAAACATTTT CAGATTCATC TCCGATTGAG 
ATAATAGATG AATTTCCCAC GTTTGTCAGT GCTAAAGATG ATTCTCCTAA ATTAGCCAAG 
GAGTACACTG ATCTAGAAGT ATCCGACAAA AGTGAAATTG CTAATATCCA AAGCGGGGCA 
GATTCATTGC CTTGCTTAGA ATTGCCCTGT GACCTTTCTT TCAAGAATAT ATATCCTAAA 
GATGAAGTAC ATGTTTCAGA TGAATTCTCC GAAAATAGGT CCAGTGTATC TAAGGCATCC 
ATATCGCCTT CAAATGTCTC TGCTTTGGAA CCTCAGACAG AAATGGGCAG CATAGTTAAA 
TCCAAATCAC TTACGAAAGA AGCAGAGAAA AAACTTCCTT CTGACACAGA GAAAGAGGAC 
AGATCCCTGT CAGCTGTATT GTCAGCAGAG CTGAGTAAAA CTTCAGTTGT TGACCTCCTC 
TACTGGAGAG ACATTAAGAA GACTGGAGTG GTGTTTGGTG CCAGCTTATT CCTGCTGCTG 
TCTCTGACAG TGTTCAGCAT TGTCAGTGTA ACGGCCTACA TTGCCTTGGC CCTGCTCTCG 
GTGACTATCA GCTTTAGGAT ATATAAGGGC GTGATCCAGG CTATCCAGAA ATCAGATGAA 
GGCCACCCAT TCAGGGCATA TTTAGAATCT GAAGTTGCTA TATCAGAGGA ATTGGTTCAG 
AAATACAGTA ATTCTGCTCT TGGTCATGTG AACAGCACAA TAAAAGAACT GAGGCGGCTT 
TTCTTAGTTG ATGATTTAGT TGATTCCCTG AAGTTTGCAG TGTTGATGTG GGTGTTTACT 
TATGTTGGTG CCTTGTTCAA TGGTCTGACA CTACTGATTT TAGCTCTGAT CTCACTCTTC 
AGTATTCCTG TTATTTATGA ACGGCATCAG GTGCAGATAG ATCATTATCT AGGACTTGCA 
AACAAGAGTG TTAAGGATGC CATGGCCAAA ATCCAAGCAA AAATCCCTGG ATTGAAGCGC 
AAAGCAGATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rtn4 ( XM_006251605.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006251667.2 Rattus norvegicus reticulon 4 (Rtn4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa58434
Clone ID Related Accession (Same CDS sequence)	XM_006251605.3
Accession Version	XM_006251605.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3480bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	reticulon-4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005113.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006251605.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAAGACA TAGACCAGTC GTCGCTGGTC TCCTCGTCCA CGGACAGCCC GCCCCGGCCT 
CCGCCCGCCT TCAAGTACCA GTTCGTGACG GAGCCCGAGG ACGAGGAGGA CGAGGAGGAG 
GAGGAGGACG AGGAGGAGGA CGACGAGGAC CTAGAGGAAC TGGAGGTGCT GGAGAGGAAG 
CCCGCAGCCG GGCTGTCCGC AGCTGCGGTG CCGCCCGCCG CCGCCGCGCC GCTGCTGGAC 
TTCAGCAGCG ACTCGGTGCC CCCCGCGCCC CGCGGGCCGC TGCCGGCCGC GCCCCCTGCC 
GCTCCTGAGA GGCAGCCATC CTGGGAACGC AGCCCCGCGG CGCCCGCGCC ATCCCTGCCG 
CCCGCTGCCG CAGTCCTGCC CTCCAAGCTC CCAGAGGACG ACGAGCCTCC GGCGAGGCCC 
CCGCCTCCGC CGCCAGCCGG CGCGAGCCCC CTGGCGGAGC CCGCCGCGCC CCCTTCCACG 
CCGGCCGCGC CCAAGCGCAG GGGCTCCGGC TCAGTGGATG AGACCCTTTT TGCTCTTCCT 
GCTGCATCTG AGCCTGTGAT ACCCTCCTCT GCAGAAAAAA TTATGGATTT GATGGAGCAG 
CCAGGTAACA CTGTTTCGTC TGGTCAAGAG GATTTCCCAT CTGTCCTGCT TGAAACTGCT 
GCCTCTCTTC CTTCTCTATC TCCTCTCTCA ACTGTTTCTT TTAAAGAACA TGGATACCTT 
GGTAACTTAT CAGCAGTGTC ATCCTCAGAA GGAACAATTG AAGAAACTTT AAATGAAGCT 
TCTAAAGAGT TGCCAGAGAG GGCAACAAAT CCATTTGTAA ATAGAGATTT AGCAGAATTT 
TCAGAATTAG AATATTCAGA AATGGGATCA TCTTTTAAAG GCTCCCCAAA AGGAGAGTCA 
GCCATATTAG TAGAAAACAC TAAGGAAGAA GTAATTGTGA GGAGTAAAGA CAAAGAGGAT 
TTAGTTTGTA GTGCAGCCCT TCACAGTCCA CAAGAATCAC CTGTGGGTAA AGAAGACAGA 
GTTGTGTCTC CAGAAAAGAC AATGGACATT TTTAATGAAA TGCAGATGTC AGTAGTAGCA 
CCTGTGAGGG AAGAGTATGC AGACTTTAAG CCATTTGAAC AAGCATGGGA AGTGAAAGAT 
ACTTATGAGG GAAGTAGGGA TGTGCTGGCT GCTAGAGCTA ATGTGGAAAG TAAAGTGGAC 
AGAAAATGCT TGGAAGATAG CCTGGAGCAA AAAAGTCTTG GGAAGGATAG TGAAGGCAGA 
AATGAGGATG CTTCTTTCCC CAGTACCCCA GAACCTGTGA AGGACAGCTC CAGAGCATAT 
ATTACCTGTG CTTCCTTTAC CTCAGCAACC GAAAGCACCA CAGCAAACAC TTTCCCTTTG 
TTAGAAGATC ATACTTCAGA AAATAAAACA GATGAAAAAA AAATAGAAGA AAGGAAGGCC 
CAAATTATAA CAGAGAAGAC TAGCCCCAAA ACGTCAAATC CTTTCCTTGT AGCAGTACAG 
GATTCTGAGG CAGATTATGT TACAACAGAT ACCTTATCAA AGGTGACTGA GGCAGCAGTG 
TCAAACATGC CTGAAGGTCT GACGCCAGAT TTAGTTCAGG AAGCATGTGA AAGTGAACTG 
AATGAAGCCA CAGGTACAAA GATTGCTTAT GAAACAAAAG TGGACTTGGT CCAAACATCA 
GAAGCTATAC AAGAATCACT TTACCCCACA GCACAGCTTT GCCCATCATT TGAGGAAGCT 
GAAGCAACTC CGTCACCAGT TTTGCCTGAT ATTGTTATGG AAGCACCATT AAATTCTCTC 
CTTCCAAGCG CTGGTGCTTC TGTAGTGCAG CCCAGTGTAT CCCCACTGGA AGCACCTCCT 
CCACTTAGTT ATGACAGTAT AAAGCTTGAG CCTGAAAACC CCCCACCATA TGAAGAAGCC 
ATGAACGTAG CACTAAAAGC TTTGGGAACA AAGGAAGGAA TAAAAGAGCC TGAAAGTTTT 
AATGCAGCTG TTCAGGAAAC AGAAGCTCCT TATATATCCA TTGCGTGTGA TTTAATTAAA 
GAAACAAAGC TCTCCACTGA GCCAAGTCCA GATTTCTCTA ATTATTCAGA AATAGCAAAA 
TTCGAGAAGT CGGTGCCCGA ACACGCTGAG CTAGTGGAGG ATTCCTCACC TGAATCTGAA 
CCAGTTGACT TATTTAGTGA TGATTCGATT CCTGAAGTCC CACAAACACA AGAGGAGGCT 
GTGATGCTCA TGAAGGAGAG TCTCACTGAA GTGTCTGAGA CAGTAGCCCA GCACAAAGAG 
GAGAGACTTA GTGCCTCACC TCAGGAGCTA GGAAAGCCAT ATTTAGAGTC TTTTCAGCCC 
AATTTACATA GTACAAAAGA TGCTGCATCT AATGACATTC CAACATTGAC CAAAAAGGAG 
AAAATTTCTT TGCAAATGGA AGAGTTTAAT ACTGCAATTT ATTCAAATGA TGACTTACTT 
TCTTCTAAGG AAGACAAAAT AAAAGAAAGT GAAACATTTT CAGATTCATC TCCGATTGAG 
ATAATAGATG AATTTCCCAC GTTTGTCAGT GCTAAAGATG ATTCTCCTAA ATTAGCCAAG 
GAGTACACTG ATCTAGAAGT ATCCGACAAA AGTGAAATTG CTAATATCCA AAGCGGGGCA 
GATTCATTGC CTTGCTTAGA ATTGCCCTGT GACCTTTCTT TCAAGAATAT ATATCCTAAA 
GATGAAGTAC ATGTTTCAGA TGAATTCTCC GAAAATAGGT CCAGTGTATC TAAGGCATCC 
ATATCGCCTT CAAATGTCTC TGCTTTGGAA CCTCAGACAG AAATGGGCAG CATAGTTAAA 
TCCAAATCAC TTACGAAAGA AGCAGAGAAA AAACTTCCTT CTGACACAGA GAAAGAGGAC 
AGATCCCTGT CAGCTGTATT GTCAGCAGAG CTGAGTAAAA CTTCAGTTGT TGACCTCCTC 
TACTGGAGAG ACATTAAGAA GACTGGAGTG GTGTTTGGTG CCAGCTTATT CCTGCTGCTG 
TCTCTGACAG TGTTCAGCAT TGTCAGTGTA ACGGCCTACA TTGCCTTGGC CCTGCTCTCG 
GTGACTATCA GCTTTAGGAT ATATAAGGGC GTGATCCAGG CTATCCAGAA ATCAGATGAA 
GGCCACCCAT TCAGGGCATA TTTAGAATCT GAAGTTGCTA TATCAGAGGA ATTGGTTCAG 
AAATACAGTA ATTCTGCTCT TGGTCATGTG AACAGCACAA TAAAAGAACT GAGGCGGCTT 
TTCTTAGTTG ATGATTTAGT TGATTCCCTG AAGTTTGCTG TGTCCACCAA CAGTGAATCT 
AACCCATGGA GGCCCAACAG AGTGCTGAGG TGTAAGCTTC TGCCAAATGA GTGTAACTGT 
GGTGTGACAC TGGAGTCTGC TTGGCGTGGT CTTCACAGGG CAGAGTGTTG TGCTGGTTTG 
CCGTCTGCTG TTCCTTCTTC AGCTCTGCCA CGCCCTGGAT CTCAGAGGAC TCTTAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006251667.2
CDS	288..3767
Translation	MEDIDQSSLVSSSTDSPPRPPPAFKYQFVTEPEDEEDEEEEEDEEEDDEDLEELEVLERKPAAGLSAAAVPPAAAAPLLDFSSDSVPPAPRGPLPAAPPAAPERQPSWERSPAAPAPSLPPAAAVLPSKLPEDDEPPARPPPPPPAGASPLAEPAAPPSTPAAPKRRGSGSVDETLFALPAASEPVIPSSAEKIMDLMEQPGNTVSSGQEDFPSVLLETAASLPSLSPLSTVSFKEHGYLGNLSAVSSSEGTIEETLNEASKELPERATNPFVNRDLAEFSELEYSEMGSSFKGSPKGESAILVENTKEEVIVRSKDKEDLVCSAALHSPQESPVGKEDRVVSPEKTMDIFNEMQMSVVAPVREEYADFKPFEQAWEVKDTYEGSRDVLAARANVESKVDRKCLEDSLEQKSLGKDSEGRNEDASFPSTPEPVKDSSRAYITCASFTSATESTTANTFPLLEDHTSENKTDEKKIEERKAQIITEKTSPKTSNPFLVAVQDSEADYVTTDTLSKVTEAAVSNMPEGLTPDLVQEACESELNEATGTKIAYETKVDLVQTSEAIQESLYPTAQLCPSFEEAEATPSPVLPDIVMEAPLNSLLPSAGASVVQPSVSPLEAPPPLSYDSIKLEPENPPPYEEAMNVALKALGTKEGIKEPESFNAAVQETEAPYISIACDLIKETKLSTEPSPDFSNYSEIAKFEKSVPEHAELVEDSSPESEPVDLFSDDSIPEVPQTQEEAVMLMKESLTEVSETVAQHKEERLSASPQELGKPYLESFQPNLHSTKDAASNDIPTLTKKEKISLQMEEFNTAIYSNDDLLSSKEDKIKESETFSDSSPIEIIDEFPTFVSAKDDSPKLAKEYTDLEVSDKSEIANIQSGADSLPCLELPCDLSFKNIYPKDEVHVSDEFSENRSSVSKASISPSNVSALEPQTEMGSIVKSKSLTKEAEKKLPSDTEKEDRSLSAVLSAELSKTSVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNSTIKELRRLFLVDDLVDSLKFAVSTNSESNPWRPNRVLRCKLLPNECNCGVTLESAWRGLHRAECCAGLPSAVPSSALPRPGSQRTLR

Target ORF information:

RefSeq Version	XM_006251605.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus reticulon 4 (Rtn4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006251605.3

ORF Insert Sequence:

ATGGAAGACA TAGACCAGTC GTCGCTGGTC TCCTCGTCCA CGGACAGCCC GCCCCGGCCT 
CCGCCCGCCT TCAAGTACCA GTTCGTGACG GAGCCCGAGG ACGAGGAGGA CGAGGAGGAG 
GAGGAGGACG AGGAGGAGGA CGACGAGGAC CTAGAGGAAC TGGAGGTGCT GGAGAGGAAG 
CCCGCAGCCG GGCTGTCCGC AGCTGCGGTG CCGCCCGCCG CCGCCGCGCC GCTGCTGGAC 
TTCAGCAGCG ACTCGGTGCC CCCCGCGCCC CGCGGGCCGC TGCCGGCCGC GCCCCCTGCC 
GCTCCTGAGA GGCAGCCATC CTGGGAACGC AGCCCCGCGG CGCCCGCGCC ATCCCTGCCG 
CCCGCTGCCG CAGTCCTGCC CTCCAAGCTC CCAGAGGACG ACGAGCCTCC GGCGAGGCCC 
CCGCCTCCGC CGCCAGCCGG CGCGAGCCCC CTGGCGGAGC CCGCCGCGCC CCCTTCCACG 
CCGGCCGCGC CCAAGCGCAG GGGCTCCGGC TCAGTGGATG AGACCCTTTT TGCTCTTCCT 
GCTGCATCTG AGCCTGTGAT ACCCTCCTCT GCAGAAAAAA TTATGGATTT GATGGAGCAG 
CCAGGTAACA CTGTTTCGTC TGGTCAAGAG GATTTCCCAT CTGTCCTGCT TGAAACTGCT 
GCCTCTCTTC CTTCTCTATC TCCTCTCTCA ACTGTTTCTT TTAAAGAACA TGGATACCTT 
GGTAACTTAT CAGCAGTGTC ATCCTCAGAA GGAACAATTG AAGAAACTTT AAATGAAGCT 
TCTAAAGAGT TGCCAGAGAG GGCAACAAAT CCATTTGTAA ATAGAGATTT AGCAGAATTT 
TCAGAATTAG AATATTCAGA AATGGGATCA TCTTTTAAAG GCTCCCCAAA AGGAGAGTCA 
GCCATATTAG TAGAAAACAC TAAGGAAGAA GTAATTGTGA GGAGTAAAGA CAAAGAGGAT 
TTAGTTTGTA GTGCAGCCCT TCACAGTCCA CAAGAATCAC CTGTGGGTAA AGAAGACAGA 
GTTGTGTCTC CAGAAAAGAC AATGGACATT TTTAATGAAA TGCAGATGTC AGTAGTAGCA 
CCTGTGAGGG AAGAGTATGC AGACTTTAAG CCATTTGAAC AAGCATGGGA AGTGAAAGAT 
ACTTATGAGG GAAGTAGGGA TGTGCTGGCT GCTAGAGCTA ATGTGGAAAG TAAAGTGGAC 
AGAAAATGCT TGGAAGATAG CCTGGAGCAA AAAAGTCTTG GGAAGGATAG TGAAGGCAGA 
AATGAGGATG CTTCTTTCCC CAGTACCCCA GAACCTGTGA AGGACAGCTC CAGAGCATAT 
ATTACCTGTG CTTCCTTTAC CTCAGCAACC GAAAGCACCA CAGCAAACAC TTTCCCTTTG 
TTAGAAGATC ATACTTCAGA AAATAAAACA GATGAAAAAA AAATAGAAGA AAGGAAGGCC 
CAAATTATAA CAGAGAAGAC TAGCCCCAAA ACGTCAAATC CTTTCCTTGT AGCAGTACAG 
GATTCTGAGG CAGATTATGT TACAACAGAT ACCTTATCAA AGGTGACTGA GGCAGCAGTG 
TCAAACATGC CTGAAGGTCT GACGCCAGAT TTAGTTCAGG AAGCATGTGA AAGTGAACTG 
AATGAAGCCA CAGGTACAAA GATTGCTTAT GAAACAAAAG TGGACTTGGT CCAAACATCA 
GAAGCTATAC AAGAATCACT TTACCCCACA GCACAGCTTT GCCCATCATT TGAGGAAGCT 
GAAGCAACTC CGTCACCAGT TTTGCCTGAT ATTGTTATGG AAGCACCATT AAATTCTCTC 
CTTCCAAGCG CTGGTGCTTC TGTAGTGCAG CCCAGTGTAT CCCCACTGGA AGCACCTCCT 
CCACTTAGTT ATGACAGTAT AAAGCTTGAG CCTGAAAACC CCCCACCATA TGAAGAAGCC 
ATGAACGTAG CACTAAAAGC TTTGGGAACA AAGGAAGGAA TAAAAGAGCC TGAAAGTTTT 
AATGCAGCTG TTCAGGAAAC AGAAGCTCCT TATATATCCA TTGCGTGTGA TTTAATTAAA 
GAAACAAAGC TCTCCACTGA GCCAAGTCCA GATTTCTCTA ATTATTCAGA AATAGCAAAA 
TTCGAGAAGT CGGTGCCCGA ACACGCTGAG CTAGTGGAGG ATTCCTCACC TGAATCTGAA 
CCAGTTGACT TATTTAGTGA TGATTCGATT CCTGAAGTCC CACAAACACA AGAGGAGGCT 
GTGATGCTCA TGAAGGAGAG TCTCACTGAA GTGTCTGAGA CAGTAGCCCA GCACAAAGAG 
GAGAGACTTA GTGCCTCACC TCAGGAGCTA GGAAAGCCAT ATTTAGAGTC TTTTCAGCCC 
AATTTACATA GTACAAAAGA TGCTGCATCT AATGACATTC CAACATTGAC CAAAAAGGAG 
AAAATTTCTT TGCAAATGGA AGAGTTTAAT ACTGCAATTT ATTCAAATGA TGACTTACTT 
TCTTCTAAGG AAGACAAAAT AAAAGAAAGT GAAACATTTT CAGATTCATC TCCGATTGAG 
ATAATAGATG AATTTCCCAC GTTTGTCAGT GCTAAAGATG ATTCTCCTAA ATTAGCCAAG 
GAGTACACTG ATCTAGAAGT ATCCGACAAA AGTGAAATTG CTAATATCCA AAGCGGGGCA 
GATTCATTGC CTTGCTTAGA ATTGCCCTGT GACCTTTCTT TCAAGAATAT ATATCCTAAA 
GATGAAGTAC ATGTTTCAGA TGAATTCTCC GAAAATAGGT CCAGTGTATC TAAGGCATCC 
ATATCGCCTT CAAATGTCTC TGCTTTGGAA CCTCAGACAG AAATGGGCAG CATAGTTAAA 
TCCAAATCAC TTACGAAAGA AGCAGAGAAA AAACTTCCTT CTGACACAGA GAAAGAGGAC 
AGATCCCTGT CAGCTGTATT GTCAGCAGAG CTGAGTAAAA CTTCAGTTGT TGACCTCCTC 
TACTGGAGAG ACATTAAGAA GACTGGAGTG GTGTTTGGTG CCAGCTTATT CCTGCTGCTG 
TCTCTGACAG TGTTCAGCAT TGTCAGTGTA ACGGCCTACA TTGCCTTGGC CCTGCTCTCG 
GTGACTATCA GCTTTAGGAT ATATAAGGGC GTGATCCAGG CTATCCAGAA ATCAGATGAA 
GGCCACCCAT TCAGGGCATA TTTAGAATCT GAAGTTGCTA TATCAGAGGA ATTGGTTCAG 
AAATACAGTA ATTCTGCTCT TGGTCATGTG AACAGCACAA TAAAAGAACT GAGGCGGCTT 
TTCTTAGTTG ATGATTTAGT TGATTCCCTG AAGTTTGCTG TGTCCACCAA CAGTGAATCT 
AACCCATGGA GGCCCAACAG AGTGCTGAGG TGTAAGCTTC TGCCAAATGA GTGTAACTGT 
GGTGTGACAC TGGAGTCTGC TTGGCGTGGT CTTCACAGGG CAGAGTGTTG TGCTGGTTTG 
CCGTCTGCTG TTCCTTCTTC AGCTCTGCCA CGCCCTGGAT CTCAGAGGAC TCTTAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rtn4 ( XM_017599393.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017454882.1 Rattus norvegicus reticulon 4 (Rtn4), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa58435
Clone ID Related Accession (Same CDS sequence)	XM_017599393.1
Accession Version	XM_017599393.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1140bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	reticulon-4 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005113.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAAGACA TAGACCAGTC GTCGCTGGTC TCCTCGTCCA CGGACAGCCC GCCCCGGCCT 
CCGCCCGCCT TCAAGTACCA GTTCGTGACG GAGCCCGAGG ACGAGGAGGA CGAGGAGGAG 
GAGGAGGACG AGGAGGAGGA CGACGAGGAC CTAGAGGAAC TGGAGGTGCT GGAGAGGAAG 
CCCGCAGCCG GGCTGTCCGC AGCTGCGGTG CCGCCCGCCG CCGCCGCGCC GCTGCTGGAC 
TTCAGCAGCG ACTCGGTGCC CCCCGCGCCC CGCGGGCCGC TGCCGGCCGC GCCCCCTGCC 
GCTCCTGAGA GGCAGCCATC CTGGGAACGC AGCCCCGCGG CGCCCGCGCC ATCCCTGCCG 
CCCGCTGCCG CAGTCCTGCC CTCCAAGCTC CCAGAGGACG ACGAGCCTCC GGCGAGGCCC 
CCGCCTCCGC CGCCAGCCGG CGCGAGCCCC CTGGCGGAGC CCGCCGCGCC CCCTTCCACG 
CCGGCCGCGC CCAAGCGCAG GGGCTCCGGC TCAGTGGATG AGACCCTTTT TGCTCTTCCT 
GCTGCATCTG AGCCTGTGAT ACCCTCCTCT GCAGTTGTTG ACCTCCTCTA CTGGAGAGAC 
ATTAAGAAGA CTGGAGTGGT GTTTGGTGCC AGCTTATTCC TGCTGCTGTC TCTGACAGTG 
TTCAGCATTG TCAGTGTAAC GGCCTACATT GCCTTGGCCC TGCTCTCGGT GACTATCAGC 
TTTAGGATAT ATAAGGGCGT GATCCAGGCT ATCCAGAAAT CAGATGAAGG CCACCCATTC 
AGGGCATATT TAGAATCTGA AGTTGCTATA TCAGAGGAAT TGGTTCAGAA ATACAGTAAT 
TCTGCTCTTG GTCATGTGAA CAGCACAATA AAAGAACTGA GGCGGCTTTT CTTAGTTGAT 
GATTTAGTTG ATTCCCTGAA GTTTGCAGTG TTGATGTGGG TGTTTACTTA TGTTGGTGCC 
TTGTTCAATG GTCTGACACT ACTGATTTTA GCTCTGATCT CACTCTTCAG TATTCCTGTT 
ATTTATGAAC GGCATCAGGT GCAGATAGAT CATTATCTAG GACTTGCAAA CAAGAGTGTT 
AAGGATGCCA TGGCCAAAAT CCAAGCAAAA ATCCCTGGAT TGAAGCGCAA AGCAGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017454882.1
CDS	271..1410
Translation	MEDIDQSSLVSSSTDSPPRPPPAFKYQFVTEPEDEEDEEEEEDEEEDDEDLEELEVLERKPAAGLSAAAVPPAAAAPLLDFSSDSVPPAPRGPLPAAPPAAPERQPSWERSPAAPAPSLPPAAAVLPSKLPEDDEPPARPPPPPPAGASPLAEPAAPPSTPAAPKRRGSGSVDETLFALPAASEPVIPSSAVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNSTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSIPVIYERHQVQIDHYLGLANKSVKDAMAKIQAKIPGLKRKAD

Target ORF information:

RefSeq Version	XM_017599393.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus reticulon 4 (Rtn4), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017599393.1

ORF Insert Sequence:

ATGGAAGACA TAGACCAGTC GTCGCTGGTC TCCTCGTCCA CGGACAGCCC GCCCCGGCCT 
CCGCCCGCCT TCAAGTACCA GTTCGTGACG GAGCCCGAGG ACGAGGAGGA CGAGGAGGAG 
GAGGAGGACG AGGAGGAGGA CGACGAGGAC CTAGAGGAAC TGGAGGTGCT GGAGAGGAAG 
CCCGCAGCCG GGCTGTCCGC AGCTGCGGTG CCGCCCGCCG CCGCCGCGCC GCTGCTGGAC 
TTCAGCAGCG ACTCGGTGCC CCCCGCGCCC CGCGGGCCGC TGCCGGCCGC GCCCCCTGCC 
GCTCCTGAGA GGCAGCCATC CTGGGAACGC AGCCCCGCGG CGCCCGCGCC ATCCCTGCCG 
CCCGCTGCCG CAGTCCTGCC CTCCAAGCTC CCAGAGGACG ACGAGCCTCC GGCGAGGCCC 
CCGCCTCCGC CGCCAGCCGG CGCGAGCCCC CTGGCGGAGC CCGCCGCGCC CCCTTCCACG 
CCGGCCGCGC CCAAGCGCAG GGGCTCCGGC TCAGTGGATG AGACCCTTTT TGCTCTTCCT 
GCTGCATCTG AGCCTGTGAT ACCCTCCTCT GCAGTTGTTG ACCTCCTCTA CTGGAGAGAC 
ATTAAGAAGA CTGGAGTGGT GTTTGGTGCC AGCTTATTCC TGCTGCTGTC TCTGACAGTG 
TTCAGCATTG TCAGTGTAAC GGCCTACATT GCCTTGGCCC TGCTCTCGGT GACTATCAGC 
TTTAGGATAT ATAAGGGCGT GATCCAGGCT ATCCAGAAAT CAGATGAAGG CCACCCATTC 
AGGGCATATT TAGAATCTGA AGTTGCTATA TCAGAGGAAT TGGTTCAGAA ATACAGTAAT 
TCTGCTCTTG GTCATGTGAA CAGCACAATA AAAGAACTGA GGCGGCTTTT CTTAGTTGAT 
GATTTAGTTG ATTCCCTGAA GTTTGCAGTG TTGATGTGGG TGTTTACTTA TGTTGGTGCC 
TTGTTCAATG GTCTGACACT ACTGATTTTA GCTCTGATCT CACTCTTCAG TATTCCTGTT 
ATTTATGAAC GGCATCAGGT GCAGATAGAT CATTATCTAG GACTTGCAAA CAAGAGTGTT 
AAGGATGCCA TGGCCAAAAT CCAAGCAAAA ATCCCTGGAT TGAAGCGCAA AGCAGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rtn4 ( XM_006251608.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006251670.2 Rattus norvegicus reticulon 4 (Rtn4), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa58436
Clone ID Related Accession (Same CDS sequence)	XM_006251608.2
Accession Version	XM_006251608.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1083bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	reticulon-4 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005113.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006251608.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAAGACA TAGACCAGTC GTCGCTGGTC TCCTCGTCCA CGGACAGCCC GCCCCGGCCT 
CCGCCCGCCT TCAAGTACCA GTTCGTGACG GAGCCCGAGG ACGAGGAGGA CGAGGAGGAG 
GAGGAGGACG AGGAGGAGGA CGACGAGGAC CTAGAGGAAC TGGAGGTGCT GGAGAGGAAG 
CCCGCAGCCG GGCTGTCCGC AGCTGCGGTG CCGCCCGCCG CCGCCGCGCC GCTGCTGGAC 
TTCAGCAGCG ACTCGGTGCC CCCCGCGCCC CGCGGGCCGC TGCCGGCCGC GCCCCCTGCC 
GCTCCTGAGA GGCAGCCATC CTGGGAACGC AGCCCCGCGG CGCCCGCGCC ATCCCTGCCG 
CCCGCTGCCG CAGTCCTGCC CTCCAAGCTC CCAGAGGACG ACGAGCCTCC GGCGAGGCCC 
CCGCCTCCGC CGCCAGCCGG CGCGAGCCCC CTGGCGGAGC CCGCCGCGCC CCCTTCCACG 
CCGGCCGCGC CCAAGCGCAG GGGCTCCGGC TCAGTGGTTG TTGACCTCCT CTACTGGAGA 
GACATTAAGA AGACTGGAGT GGTGTTTGGT GCCAGCTTAT TCCTGCTGCT GTCTCTGACA 
GTGTTCAGCA TTGTCAGTGT AACGGCCTAC ATTGCCTTGG CCCTGCTCTC GGTGACTATC 
AGCTTTAGGA TATATAAGGG CGTGATCCAG GCTATCCAGA AATCAGATGA AGGCCACCCA 
TTCAGGGCAT ATTTAGAATC TGAAGTTGCT ATATCAGAGG AATTGGTTCA GAAATACAGT 
AATTCTGCTC TTGGTCATGT GAACAGCACA ATAAAAGAAC TGAGGCGGCT TTTCTTAGTT 
GATGATTTAG TTGATTCCCT GAAGTTTGCA GTGTTGATGT GGGTGTTTAC TTATGTTGGT 
GCCTTGTTCA ATGGTCTGAC ACTACTGATT TTAGCTCTGA TCTCACTCTT CAGTATTCCT 
GTTATTTATG AACGGCATCA GGTGCAGATA GATCATTATC TAGGACTTGC AAACAAGAGT 
GTTAAGGATG CCATGGCCAA AATCCAAGCA AAAATCCCTG GATTGAAGCG CAAAGCAGAT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006251670.2
CDS	269..1351
Translation	MEDIDQSSLVSSSTDSPPRPPPAFKYQFVTEPEDEEDEEEEEDEEEDDEDLEELEVLERKPAAGLSAAAVPPAAAAPLLDFSSDSVPPAPRGPLPAAPPAAPERQPSWERSPAAPAPSLPPAAAVLPSKLPEDDEPPARPPPPPPAGASPLAEPAAPPSTPAAPKRRGSGSVVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNSTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSIPVIYERHQVQIDHYLGLANKSVKDAMAKIQAKIPGLKRKAD

Target ORF information:

RefSeq Version	XM_006251608.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus reticulon 4 (Rtn4), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006251608.2

ORF Insert Sequence:

ATGGAAGACA TAGACCAGTC GTCGCTGGTC TCCTCGTCCA CGGACAGCCC GCCCCGGCCT 
CCGCCCGCCT TCAAGTACCA GTTCGTGACG GAGCCCGAGG ACGAGGAGGA CGAGGAGGAG 
GAGGAGGACG AGGAGGAGGA CGACGAGGAC CTAGAGGAAC TGGAGGTGCT GGAGAGGAAG 
CCCGCAGCCG GGCTGTCCGC AGCTGCGGTG CCGCCCGCCG CCGCCGCGCC GCTGCTGGAC 
TTCAGCAGCG ACTCGGTGCC CCCCGCGCCC CGCGGGCCGC TGCCGGCCGC GCCCCCTGCC 
GCTCCTGAGA GGCAGCCATC CTGGGAACGC AGCCCCGCGG CGCCCGCGCC ATCCCTGCCG 
CCCGCTGCCG CAGTCCTGCC CTCCAAGCTC CCAGAGGACG ACGAGCCTCC GGCGAGGCCC 
CCGCCTCCGC CGCCAGCCGG CGCGAGCCCC CTGGCGGAGC CCGCCGCGCC CCCTTCCACG 
CCGGCCGCGC CCAAGCGCAG GGGCTCCGGC TCAGTGGTTG TTGACCTCCT CTACTGGAGA 
GACATTAAGA AGACTGGAGT GGTGTTTGGT GCCAGCTTAT TCCTGCTGCT GTCTCTGACA 
GTGTTCAGCA TTGTCAGTGT AACGGCCTAC ATTGCCTTGG CCCTGCTCTC GGTGACTATC 
AGCTTTAGGA TATATAAGGG CGTGATCCAG GCTATCCAGA AATCAGATGA AGGCCACCCA 
TTCAGGGCAT ATTTAGAATC TGAAGTTGCT ATATCAGAGG AATTGGTTCA GAAATACAGT 
AATTCTGCTC TTGGTCATGT GAACAGCACA ATAAAAGAAC TGAGGCGGCT TTTCTTAGTT 
GATGATTTAG TTGATTCCCT GAAGTTTGCA GTGTTGATGT GGGTGTTTAC TTATGTTGGT 
GCCTTGTTCA ATGGTCTGAC ACTACTGATT TTAGCTCTGA TCTCACTCTT CAGTATTCCT 
GTTATTTATG AACGGCATCA GGTGCAGATA GATCATTATC TAGGACTTGC AAACAAGAGT 
GTTAAGGATG CCATGGCCAA AATCCAAGCA AAAATCCCTG GATTGAAGCG CAAAGCAGAT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Nogo-A interacts with TrkA to alter nerve growth factor signaling in Nogo-A-overexpressing PC12 cells.
Cellular signalling4420-27(2018 Jan)
Farrer RG,Kartje GL

Towards Functional Annotation of the Preimplantation Transcriptome: An RNAi Screen in Mammalian Embryos.
Scientific reports637396(2016 Nov)
Cui W,Dai X,Marcho C,Han Z,Zhang K,Tremblay KD,Mager J

Nogo-C regulates cardiomyocyte apoptosis during mouse myocardial infarction.
Cell death & disease7(10)e2432(2016 Oct)
Jia S,Qiao X,Ye J,Fang X,Xu C,Cao Y,Zheng M

NOGO-A/RTN4A and NOGO-B/RTN4B are simultaneously expressed in epithelial, fibroblast and neuronal cells and maintain ER morphology.
Scientific reports635969(2016 Oct)
R?m? O,Kumar D,Gucciardo E,Joensuu M,Saarekas M,Vihinen H,Belevich I,Smolander OP,Qian K,Auvinen P,Jokitalo E

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

Rtn4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報