Kcnma1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Kcnma1
Entrez Gene ID	83731
Full Name	potassium calcium-activated channel subfamily M alpha 1
Synonyms	BKCa,KCNMA1b,KCNMA1c,Kcnma,Slo,cbv1
General protein information	Preferred Names potassium calcium-activated channel subfamily M alpha 1 Names calcium-activated potassium channel subunit alpha-1 BK channel BKCA alpha KCa1.1 calcium-activated potassium channel alpha subunit calcium-activated potassium channel, subfamily M subunit alpha-1 k(VCA)alpha maxi K channel maxiK potassium channel, calcium activated large conductance subfamily M alpha, member 1 potassium large conductance calcium-activated channel, subfamily M, alpha member 1 slo homolog slo-alpha slo1 slowpoke homolog
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 15 Map Location: 15p16
Summary	large-conductance Ca(2+)-activated K(+) channel; may be involved in the shortened duration of action potential in hippocampal CA1 pyramidal neurons and in channel activity in carotid body chemoreceptor cells [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_031828.1	NP_114016.1	calcium-activated potassium channel subunit alpha-1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	KCNMA1	XP_003312698.2
Mus musculus (house mouse)	Kcnma1	NP_001240293.1
Gallus gallus (chicken)	KCNMA1	NP_989555.1
Bos taurus (cattle)	KCNMA1	NP_777105.1
Danio rerio (zebrafish)	kcnma1a	NP_001139072.1
Drosophila melanogaster (fruit fly)	slo	NP_001014652.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP003709	XP_003436577.1
Canis lupus familiaris (dog)	KCNMA1	NP_001003300.1
Rattus norvegicus (Norway rat)	Kcnma1	NP_114016.1
Homo sapiens (human)	KCNMA1	NP_001154824.1
Caenorhabditis elegans (roundworm)	slo-1	NP_001024259.1
Xenopus tropicalis (tropical clawed frog)	kcnma1	XP_004916071.1

Gene Ontology
Bibliography

Related articles in PubMed

Stimulatory actions of a novel thiourea derivative on large-conductance, calcium-activated potassium channels.
Wu SN, Chern JH, Shen S, Chen HH, Hsu YT, Lee CC, Chan MH, Lai MC, Shie FS
Journal of cellular physiology232(12)3409-3421(2017 Dec)

Underlying mechanisms preserving coronary basal tone and NO-mediated relaxation in obesity: Involvement of ?1 subunit-mediated upregulation of BK
Climent B, S?nchez A, Moreno L, P?rez-Vizca?no F, Garc?a-Sacrist?n A, Rivera L, Prieto D
Atherosclerosis263227-236(2017 Aug)

Proximal clustering between BK and Ca
Vivas O, Moreno CM, Santana LF, Hille B
eLife6(2017 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Thiourea derivative, compound 326, stimulates the activity of large-conductance, calcium-activated potassium channels.
Title: Stimulatory actions of a novel thiourea derivative on large-conductance, calcium-activated potassium channels.

Results showed that BK-knockout osteoblasts displayed low proliferation and impaired mineralization ability providing further evidence that BK channel is critical for osteoblast function.
Title: BK Knockout by TALEN-Mediated Gene Targeting in Osteoblasts: KCNMA1 Determines the Proliferation and Differentiation of Osteoblasts.

Taken together, BKCa channel activation attenuates these Ca(2+) oscillations due to depolarization-synchronized Ca(2+) influx through VDCCs and results in a recovery of reduced melatonin secretion during parasympathetic nerve activity. BKCa channels may play a physiological role for melatonin production via a negative-feedback mechanism.
Title: Modulation of Ca2+ oscillation and melatonin secretion by BKCa channel activity in rat pinealocytes.

SLO2 Channels Are Inhibited by All Divalent Cations That Activate SLO1 K+ Channels
Title: SLO2 Channels Are Inhibited by All Divalent Cations That Activate SLO1 K+ Channels.

Coupling of Orai1-BKCa channel has a hyperpolarizing effect in mesenteric artery smooth muscle.
Title: Orai1 forms a signal complex with BKCa channel in mesenteric artery smooth muscle cells.

The following Kcnma1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Kcnma1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa12942	NM_031828.1 Latest version!	Rattus norvegicus potassium calcium-activated channel subfamily M alpha 1 (Kcnma1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$643.30 $919.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Kcnma1 ( NM_031828.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_114016.1 Rattus norvegicus potassium calcium-activated channel subfamily M alpha 1 (Kcnma1), mRNA.

Price & Availability↑

CloneID	ORa12942
Clone ID Related Accession (Same CDS sequence)	NM_031828.1
Accession Version	NM_031828.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3732bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Rattus norvegicus(Norway rat)
Product	calcium-activated potassium channel subunit alpha-1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U40603.1. On Dec 17, 2003 this sequence version replaced XM_346471.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U40603.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGCAAACG GTGGCGGCGG CGGCGGCGGC GGCAGCAGCG GCAGCAGCGG CGGCGGCGGC 
GGCGGCGGCG GAGGCGAGAC GGCTCTTAGA ATGAGCAGCA ATATCCACGC GAACCATCTC 
AGCCTAGACG CGTCCTCTTC TTCCTCCTCC TCTTCTTCCT CCTCCTCTTC CTCCTCGTCC 
TCGGTCCACG AGCCCAAGAT GGATGCGCTC ATCATCCCGG TGACCATGGA GGTGCCGTGC 
GACAGCCGGG GCCAACGCAT GTGGTGGGCT TTCTTGGCCT CCTCCATGGT GACTTTCTTC 
GGGGGCCTCT TCATCATCTT GCTCTGGCGG ACTCTCAAGT ACCTGTGGAC CGTTTGCTGC 
CACTGCGGGG GCAAGACGAA GGAGGCCCAG AAGATAAACA ATGGCTCCAG CCAGGCAGAT 
GGTACTCTCA AGCCAGTGGA TGAAAAAGAG GAGGTGGTGG CAGCCGAGGT CGGCTGGATG 
ACATCTGTGA AGGACTGGGC AGGGGTGATG ATATCTGCCC AGACACTGAC TGGCAGAGTC 
CTGGTTGTGT TAGTCTTTGC TCTCAGCATT GGTGCCCTTG TAATATACTT CATAGACTCA 
TCAAACCCAA TAGAATCCTG CCAGAATTTC TACAAAGATT TCACATTACA GATCGACATG 
GCTTTCAACG TGTTCTTCCT TCTCTACTTT GGCTTGCGGT TTATTGCAGC CAATGATAAG 
CTGTGGTTCT GGCTGGAAGT GAATTCTGTA GTAGATTTCT TCACAGTCCC TCCCGTGTTT 
GTGTCTGTAT ACTTAAACAG AAGTTGGCTT GGCTTGAGAT TTTTAAGAGC TCTCAGACTG 
ATTCAGTTTT CAGAAATTTT GCAGTTTCTG AATATCCTTA AAACAAGTAA TTCCATCAAG 
CTGGTGAACC TGCTCTCCAT ATTTATCAGC ACGTGGCTGA CTGCAGCTGG ATTCATCCAC 
TTGGTGGAGA ATTCAGGGGA CCCATGGGAA AATTTCCAAA ACAACCAGGC ACTTACGTAC 
TGGGAATGTG TCTACTTACT CATGGTCACA ATGTCTACAG TGGGTTACGG GGATGTTTAT 
GCAAAAACCA CGCTTGGACG CCTCTTCATG GTCTTCTTCA TCCTCGGGGG ACTGGCCATG 
TTTGCCAGCT ACGTCCCTGA AATCATAGAG TTAATAGGAA ACCGCAAGAA ATACGGGGGC 
TCCTATAGCG CGGTTAGTGG AAGAAAGCAC ATTGTAGTCT GTGGGCACAT TACTCTGGAG 
AGTGTCTCTA ACTTCCTGAA GGACTTTCTG CACAAGGACC GGGATGATGT CAACGTGGAG 
ATTGTTTTTC TTCACAACAT CTCCCCTAAC CTTGAGCTTG AGGCTCTGTT CAAACGGCAT 
TTCACTCAGG TGGAGTTTTA TCAGGGCTCT GTCCTCAATC CACACGATCT TGCCAGAGTC 
AAGATAGAGT CAGCAGATGC ATGTTTGATC CTTGCCAATA AGTACTGCGC TGACCCGGAT 
GCAGAAGATG CCTCCAACAT CATGAGAGTG ATCTCCATAA AGAACTACCA CCCAAAGATC 
AGGATCATCA CTCAGATGCT GCAGTATCAC AACAAGGCCC ATCTGCTCAA CATCCCCAGC 
TGGAACTGGA AAGAGGGTGA TGACGCAATA TGCCTTGCAG AGCTCAAGTT GGGTTTCATA 
GCCCAGAGCT GTCTGGCTCA AGGCCTCTCC ACAATGCTTG CCAATCTCTT CTCTATGAGG 
TCATTCATAA AGATTGAGGA AGATACATGG CAGAAATACT ACTTGGAAGG AGTCTCCAAT 
GAAATGTACA CAGAATATCT TTCCAGTGCC TTCGTGGGTC TGTCCTTCCC TACTGTTTGT 
GAGCTGTGTT TTGTGAAGCT TAAGCTCCTG ATGATAGCCA TTGAGTACAA GTCTGCCAAC 
AGGGAGAGCC GAAGCCGAAA GCGAATATTA ATTAACCCTG GGAACCACCT TAAGACCCAA 
GAAGGTACTT TAGGATTTTT CATCGCAAGT GATGCCAAAG AAGTTAAAAG GGCATTTTTT 
TACTGCAAGG CCTGTCATGA TGACGTCACA GATCCCAAAA GAATTAAAAA ATGCGGCTGC 
AGGCGGCTGA TCTATTCCAA GATGTCCATC TACAAGAGAA TGAGCCGAGC ATGTTGTTTT 
GATTGCGGAC GTTCTGAGCG TGACTGCTCG TGCATGTCAG GCCGTGTGCG TGGTAACGTG 
GACACCCTTG AGAGAAACTT CCCGCTTTCT TCTGTCTCTG TTAATGATTG CTCCACCAGT 
TTCCGTGCCT TTGAAGATGA GCAACCGCCA ACACTGTCAC CAAAAAAAAA ACAACGTAAT 
GGGGGCATGA GGAACTCACC CAACACATCC CCGAAGCTGA TGAGGCATGA CCCCTTGTTA 
ATTCCTGGCA ACGATCAGAT TGACAACATG GACTCCAATG TGAAAAAGTA CGACTCCACT 
GGAATGTTTC ACTGGTGCGC ACCCAAGGAG ATTGAGAAAG TCATCTTGAC TCGAAGTGAA 
GCTGCCATGA CTGTCCTGAG TGGTCATGTT GTAGTCTGCA TCTTTGGGGA TGTCAGCTCA 
GCCCTGATTG GCCTCCGGAA CCTGGTGATG CCGCTTCGTG CTAGCAATTT TCACTATCAT 
GAGCTCAAAC ACATTGTGTT TGTGGGCTCC ATCGAGTACC TCAAGCGGGA GTGGGAAACA 
CTGCACAACT TCCCCAAAGT ATCCATATTG CCTGGTACGC CATTAAGTCG GGCTGATTTA 
AGGGCTGTCA ACATCAACCT CTGTGACATG TGCGTTATCC TGTCAGCCAA TCAGAATAAT 
ATTGATGATA CTTCGCTTCA GGACAAGGAA TGCATCTTGG CGTCACTCAA CATCAAATCT 
ATGCAGTTTG ATGACAGCAT CGGGGTCTTG CAGGCTAATT CCCAAGGATT CACACCTCCT 
GGAATGGACA GATCATCACC TGACAACAGC CCAGTGCACG GGATGTTACG CCAGCCGTCC 
ATCACAACCG GAGTCAACAT TCCCATCATC ACGGAACTCG TGAACGATAC TAATGTTCAG 
TTTTTGGACC AAGATGATGA TGATGACCCT GACACAGAGC TGTACCTCAC ACAGCCCTTT 
GCTTGTGGGA CAGCATTTGC CGTTAGCGTC CTGGACTCAC TCATGAGCGC GACATACTTC 
AATGACAATA TCCTCACCCT AATACGGACC CTGGTGACAG GAGGAGCCAC GCCAGAGCTC 
GAAGCTTTAA TAGCTGAGGA GAATGCACTT CGAGGGGGTT ACAGCACTCC GCAGACACTA 
GCCAACAGGG ACCGCTGCCG AGTGGCCCAG TTAGCCCTGT TGGATGGGCC CTTTGCGGAC 
TTAGGGGATG GTGGTTGTTA TGGTGATCTG TTCTGCAAAG CTCTGAAAAC ATATAACATG 
CTTTGTTTTG GAATTTACCG GCTGAGAGAT GCCCACCTCA GCACCCCCAG CCAGTGTACA 
AAAAGGTACG TCATCACCAA TCCCCCCTAC GAGTTTGAAC TTGTACCGAC AGACCTGATC 
TTCTGCCTGA TGCAGTTTGA CCACAACGCT GGCCAATCCC GGGCCAGTCT GTCTCATTCC 
TCCCACTCCT CACAGTCGTC CAGTAAGAAG AGCTCCTCTG TCCACTCCAT CCCGTCCACA 
GCAAATCGGC CAAACCGGCC CAAGTCCAGG GAGTCCCGCG ACAAACAGAA AAAAGAAATG 
GTTTACAGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_114016.1
CDS	493..4224
Translation	MANGGGGGGGGSSGSSGGGGGGGGGETALRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSVHEPKMDALIIPVTMEVPCDSRGQRMWWAFLASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEVVAAEVGWMTSVKDWAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRSRKRILINPGNHLKTQEGTLGFFIASDAKEVKRAFFYCKACHDDVTDPKRIKKCGCRRLIYSKMSIYKRMSRACCFDCGRSERDCSCMSGRVRGNVDTLERNFPLSSVSVNDCSTSFRAFEDEQPPTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSSKKSSSVHSIPSTANRPNRPKSRESRDKQKKEMVYR

Target ORF information:

RefSeq Version	NM_031828.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus potassium calcium-activated channel subfamily M alpha 1 (Kcnma1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031828.1

ORF Insert Sequence:

ATGGCAAACG GTGGCGGCGG CGGCGGCGGC GGCAGCAGCG GCAGCAGCGG CGGCGGCGGC 
GGCGGCGGCG GAGGCGAGAC GGCTCTTAGA ATGAGCAGCA ATATCCACGC GAACCATCTC 
AGCCTAGACG CGTCCTCTTC TTCCTCCTCC TCTTCTTCCT CCTCCTCTTC CTCCTCGTCC 
TCGGTCCACG AGCCCAAGAT GGATGCGCTC ATCATCCCGG TGACCATGGA GGTGCCGTGC 
GACAGCCGGG GCCAACGCAT GTGGTGGGCT TTCTTGGCCT CCTCCATGGT GACTTTCTTC 
GGGGGCCTCT TCATCATCTT GCTCTGGCGG ACTCTCAAGT ACCTGTGGAC CGTTTGCTGC 
CACTGCGGGG GCAAGACGAA GGAGGCCCAG AAGATAAACA ATGGCTCCAG CCAGGCAGAT 
GGTACTCTCA AGCCAGTGGA TGAAAAAGAG GAGGTGGTGG CAGCCGAGGT CGGCTGGATG 
ACATCTGTGA AGGACTGGGC AGGGGTGATG ATATCTGCCC AGACACTGAC TGGCAGAGTC 
CTGGTTGTGT TAGTCTTTGC TCTCAGCATT GGTGCCCTTG TAATATACTT CATAGACTCA 
TCAAACCCAA TAGAATCCTG CCAGAATTTC TACAAAGATT TCACATTACA GATCGACATG 
GCTTTCAACG TGTTCTTCCT TCTCTACTTT GGCTTGCGGT TTATTGCAGC CAATGATAAG 
CTGTGGTTCT GGCTGGAAGT GAATTCTGTA GTAGATTTCT TCACAGTCCC TCCCGTGTTT 
GTGTCTGTAT ACTTAAACAG AAGTTGGCTT GGCTTGAGAT TTTTAAGAGC TCTCAGACTG 
ATTCAGTTTT CAGAAATTTT GCAGTTTCTG AATATCCTTA AAACAAGTAA TTCCATCAAG 
CTGGTGAACC TGCTCTCCAT ATTTATCAGC ACGTGGCTGA CTGCAGCTGG ATTCATCCAC 
TTGGTGGAGA ATTCAGGGGA CCCATGGGAA AATTTCCAAA ACAACCAGGC ACTTACGTAC 
TGGGAATGTG TCTACTTACT CATGGTCACA ATGTCTACAG TGGGTTACGG GGATGTTTAT 
GCAAAAACCA CGCTTGGACG CCTCTTCATG GTCTTCTTCA TCCTCGGGGG ACTGGCCATG 
TTTGCCAGCT ACGTCCCTGA AATCATAGAG TTAATAGGAA ACCGCAAGAA ATACGGGGGC 
TCCTATAGCG CGGTTAGTGG AAGAAAGCAC ATTGTAGTCT GTGGGCACAT TACTCTGGAG 
AGTGTCTCTA ACTTCCTGAA GGACTTTCTG CACAAGGACC GGGATGATGT CAACGTGGAG 
ATTGTTTTTC TTCACAACAT CTCCCCTAAC CTTGAGCTTG AGGCTCTGTT CAAACGGCAT 
TTCACTCAGG TGGAGTTTTA TCAGGGCTCT GTCCTCAATC CACACGATCT TGCCAGAGTC 
AAGATAGAGT CAGCAGATGC ATGTTTGATC CTTGCCAATA AGTACTGCGC TGACCCGGAT 
GCAGAAGATG CCTCCAACAT CATGAGAGTG ATCTCCATAA AGAACTACCA CCCAAAGATC 
AGGATCATCA CTCAGATGCT GCAGTATCAC AACAAGGCCC ATCTGCTCAA CATCCCCAGC 
TGGAACTGGA AAGAGGGTGA TGACGCAATA TGCCTTGCAG AGCTCAAGTT GGGTTTCATA 
GCCCAGAGCT GTCTGGCTCA AGGCCTCTCC ACAATGCTTG CCAATCTCTT CTCTATGAGG 
TCATTCATAA AGATTGAGGA AGATACATGG CAGAAATACT ACTTGGAAGG AGTCTCCAAT 
GAAATGTACA CAGAATATCT TTCCAGTGCC TTCGTGGGTC TGTCCTTCCC TACTGTTTGT 
GAGCTGTGTT TTGTGAAGCT TAAGCTCCTG ATGATAGCCA TTGAGTACAA GTCTGCCAAC 
AGGGAGAGCC GAAGCCGAAA GCGAATATTA ATTAACCCTG GGAACCACCT TAAGACCCAA 
GAAGGTACTT TAGGATTTTT CATCGCAAGT GATGCCAAAG AAGTTAAAAG GGCATTTTTT 
TACTGCAAGG CCTGTCATGA TGACGTCACA GATCCCAAAA GAATTAAAAA ATGCGGCTGC 
AGGCGGCTGA TCTATTCCAA GATGTCCATC TACAAGAGAA TGAGCCGAGC ATGTTGTTTT 
GATTGCGGAC GTTCTGAGCG TGACTGCTCG TGCATGTCAG GCCGTGTGCG TGGTAACGTG 
GACACCCTTG AGAGAAACTT CCCGCTTTCT TCTGTCTCTG TTAATGATTG CTCCACCAGT 
TTCCGTGCCT TTGAAGATGA GCAACCGCCA ACACTGTCAC CAAAAAAAAA ACAACGTAAT 
GGGGGCATGA GGAACTCACC CAACACATCC CCGAAGCTGA TGAGGCATGA CCCCTTGTTA 
ATTCCTGGCA ACGATCAGAT TGACAACATG GACTCCAATG TGAAAAAGTA CGACTCCACT 
GGAATGTTTC ACTGGTGCGC ACCCAAGGAG ATTGAGAAAG TCATCTTGAC TCGAAGTGAA 
GCTGCCATGA CTGTCCTGAG TGGTCATGTT GTAGTCTGCA TCTTTGGGGA TGTCAGCTCA 
GCCCTGATTG GCCTCCGGAA CCTGGTGATG CCGCTTCGTG CTAGCAATTT TCACTATCAT 
GAGCTCAAAC ACATTGTGTT TGTGGGCTCC ATCGAGTACC TCAAGCGGGA GTGGGAAACA 
CTGCACAACT TCCCCAAAGT ATCCATATTG CCTGGTACGC CATTAAGTCG GGCTGATTTA 
AGGGCTGTCA ACATCAACCT CTGTGACATG TGCGTTATCC TGTCAGCCAA TCAGAATAAT 
ATTGATGATA CTTCGCTTCA GGACAAGGAA TGCATCTTGG CGTCACTCAA CATCAAATCT 
ATGCAGTTTG ATGACAGCAT CGGGGTCTTG CAGGCTAATT CCCAAGGATT CACACCTCCT 
GGAATGGACA GATCATCACC TGACAACAGC CCAGTGCACG GGATGTTACG CCAGCCGTCC 
ATCACAACCG GAGTCAACAT TCCCATCATC ACGGAACTCG TGAACGATAC TAATGTTCAG 
TTTTTGGACC AAGATGATGA TGATGACCCT GACACAGAGC TGTACCTCAC ACAGCCCTTT 
GCTTGTGGGA CAGCATTTGC CGTTAGCGTC CTGGACTCAC TCATGAGCGC GACATACTTC 
AATGACAATA TCCTCACCCT AATACGGACC CTGGTGACAG GAGGAGCCAC GCCAGAGCTC 
GAAGCTTTAA TAGCTGAGGA GAATGCACTT CGAGGGGGTT ACAGCACTCC GCAGACACTA 
GCCAACAGGG ACCGCTGCCG AGTGGCCCAG TTAGCCCTGT TGGATGGGCC CTTTGCGGAC 
TTAGGGGATG GTGGTTGTTA TGGTGATCTG TTCTGCAAAG CTCTGAAAAC ATATAACATG 
CTTTGTTTTG GAATTTACCG GCTGAGAGAT GCCCACCTCA GCACCCCCAG CCAGTGTACA 
AAAAGGTACG TCATCACCAA TCCCCCCTAC GAGTTTGAAC TTGTACCGAC AGACCTGATC 
TTCTGCCTGA TGCAGTTTGA CCACAACGCT GGCCAATCCC GGGCCAGTCT GTCTCATTCC 
TCCCACTCCT CACAGTCGTC CAGTAAGAAG AGCTCCTCTG TCCACTCCAT CCCGTCCACA 
GCAAATCGGC CAAACCGGCC CAAGTCCAGG GAGTCCCGCG ACAAACAGAA AAAAGAAATG 
GTTTACAGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Stimulatory actions of a novel thiourea derivative on large-conductance, calcium-activated potassium channels.
Journal of cellular physiology232(12)3409-3421(2017 Dec)
Wu SN,Chern JH,Shen S,Chen HH,Hsu YT,Lee CC,Chan MH,Lai MC,Shie FS

Underlying mechanisms preserving coronary basal tone and NO-mediated relaxation in obesity: Involvement of ?1 subunit-mediated upregulation of BK
Atherosclerosis263227-236(2017 Aug)
Climent B,S?nchez A,Moreno L,P?rez-Vizca?no F,Garc?a-Sacrist?n A,Rivera L,Prieto D

Proximal clustering between BK and Ca
eLife6(2017 Jun)
Vivas O,Moreno CM,Santana LF,Hille B

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Kcnma1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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