Timeless cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Timeless
Entrez Gene ID	83508
Full Name	timeless circadian regulator
Synonyms	Tim
General protein information	Preferred Names timeless circadian regulator Names protein timeless homolog rTIM rTLP timeless circadian clock timeless homolog timeless-like protein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 7 Map Location: 7q11
Summary	The protein encoded by this gene is highly conserved and is involved in cell survival after damage or stress, increase in DNA polymerase epsilon activity, maintenance of telomere length, and epithelial cell morphogenesis. The encoded protein also plays a role in the circadian rhythm autoregulatory loop, interacting with the Period genes (Per1, Per2, and Per3) and others to downregulate activation of Per1 by Clock/Arntl. Changes in this gene or its expression may promote prostate cancer, lung cancer, breast cancer, and mental disorders. [provided by RefSeq, Feb 2014].

mRNA and Protein(s)

mRNA	Protein	Name
NM_031340.1	NP_112630.1	protein timeless homolog

Pathways from BioSystems

Homologies

Homo sapiens (human)	TIMELESS	NP_003911.2
Canis lupus familiaris (dog)	TIMELESS	XP_538233.3
Pan troglodytes (chimpanzee)	TIMELESS	XP_509535.2
	LOC712835	XP_002808027.1
Danio rerio (zebrafish)	timeless	NP_001265529.1
Xenopus tropicalis (tropical clawed frog)	timeless	XP_002934575.1
Bos taurus (cattle)	TIMELESS	NP_001095541.2
Mus musculus (house mouse)	Timeless	NP_035719.1
Rattus norvegicus (Norway rat)	Timeless	NP_112630.1
Drosophila melanogaster (fruit fly)	timeout	NP_524341.3
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010787	XP_001689129.1

Gene Ontology
Bibliography

Related articles in PubMed

Timeless Interacts with PARP-1 to Promote Homologous Recombination Repair.
Xie S, Mortusewicz O, Ma HT, Herr P, Poon RY, Poon RR, Helleday T, Qian C
Molecular cell60(1)163-76(2015 Oct)

Modulation of ATR-mediated DNA damage checkpoint response by cryptochrome 1.
Kang TH, Leem SH
Nucleic acids research42(7)4427-34(2014 Apr)

Roles of ChlR1 DNA helicase in replication recovery from DNA damage.
Shah N, Inoue A, Woo Lee S, Beishline K, Lahti JM, Noguchi E
Experimental cell research319(14)2244-53(2013 Aug)

Mammalian TIMELESS is involved in period determination and DNA damage-dependent phase advancing of the circadian clock.
Engelen E, Janssens RC, Yagita K, Smits VA, van der Horst GT, Tamanini F
PloS one8(2)e56623(2013)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

data presented provide functional evidence that Full-length mammalian Timeless protein (mTIM-fl) is required for expression of suprachiasmatic nucleus circadian rhythmicity
Title: Requirement of mammalian Timeless for circadian rhythmicity.

The following Timeless gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Timeless cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa07866	NM_031340.1 Latest version!	Rattus norvegicus timeless circadian regulator (Timeless), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$643.30 $919.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Timeless ( NM_031340.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_112630.1 Rattus norvegicus timeless circadian regulator (Timeless), mRNA.

Price & Availability↑

CloneID	ORa07866
Clone ID Related Accession (Same CDS sequence)	NM_031340.1
Accession Version	NM_031340.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3618bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-22
Organism	Rattus norvegicus(Norway rat)
Product	protein timeless homolog
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB019576.1. On Dec 17, 2003 this sequence version replaced XM_346788.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB019576.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGACTTGT ACATGATGAA CTGTGAACTT CTAGCCACTT GTAGCGCCCT TGGGTACTTG 
GAAGGAGGCA CTTACCACAA GGAGCCGGAC TGCTTGGAGA GTGTGAAGGA TTTGATCCGA 
TACCTGAGGC ATGAGGACGA GACTCGAGAT GTGCGGCAGC AGCTGGGAGC CGCGCAGATC 
CTGCAGAGTG ATCTCCTGCC AATCCTCACC CAGCACCGCC AGGACAAGCC TCTCTTTGAT 
GCTGTGATCA GGCTGATGGT AAATTTGACT CAGCCAGCCT TGCTCTGTTT TGGCAGCGTG 
CCTAAGGACC CCACTGTACG ACACCATTTT CTGCAGGTTC TAACCTACCT GCAGGCCTAC 
AAAGAGGCCT TTGCCAGTGA AAAGGCATTT GGAGTCCTCA GCGAAACCTT GTATGAGCTA 
CTGCAGCTGG GCTGGGAGGA TCGGCAAGAA GAAGACAACT TGCTGATTGA ACGGATCCTT 
CTGTTGGTCA GAAATATTCT CCATGTCCCA GCCAACCTTG AGCAGGAGAA GAGGATCGAT 
GACGATGCCA GCATTCATGA CCGGCTTCTG TGGGCAATTC ACCTCAGTGG CATGGACGAC 
TTGCTCCTCT TCCTGTCCAG CTCATCCGCT GAGCAGCAGT GGAGCCTCCA TGTGCTGGAG 
ATCATCTCCC TCATGTTCCG AGACCAGAAG CCTGAGCAGC TGGCAGGAGT AGGGCAGGGA 
CGCTTGGCTC AGGAGCGAAG CACAGATTTG GCAGAATTGG AAGTGCTGCG CCAACGGGAG 
GTGGCCGAGA AGAGAGCCCG AGCCCTGCAG CGAGGAAACA GGCACTCTCG ATTTGGGGGC 
TCCTATGTTG TCCAGGGGTT GAAATCTATT GGGGAGAGGG ATGTCGTCTT TCACAAAGGC 
CTTCACAACC TCCAGAACTA CAGCTCAGAT CTAGGAAAGC AGCCCCGGAG GGTGCCTAAG 
CGTCGTCAGG CTGCCCAGGA GCTGTCTGTC CATCGCCGCT CTGTCCTGAA TGTGAGGCTC 
TTCCTCAGAG ACTTCTGCTC TGAGTTCCTG GAGAACTGTT ACAACCCACT CATGGGTGCA 
GTCAAGGATC ACCTGCTTCG GGAGAAAGCT CAGCAACATG ATGAGACGTA CTACATGTGG 
GCGATGGCTT TCTTTATGGC CTTCAACCGA GCTGCTGCCT TCCGCCCTGG CTTTGTCTCT 
GAGACCCTCA GTATCCGGAC CTTTCACTTT GTGGAGCAGA ACCTCACCAA CTACTATGAG 
ATGATGCTGA CAGACCGCAA GGAGGCCGCC TCCTGGGCAC GCAGGATGCA CCTGGCTCTG 
AAGGCCTATC AGGAGCTGCT GGCCACAGTG AATGAGATGG ACATGTGCCC AGACGACGCT 
GTCAGGGAGA GCAGTCGCAT CATCAAAAAC AACATTTTCT ACATGATGGA GTACCGAGAA 
CTATTTCTGG CACTCTTTCG AAAATTCGAT GAGAGATACC ATCCACGTTC ATTCCTTTGT 
GACCTGGTGG AGACCACTCA CCTCTTCCTC AAAATGTTGG AGCGCTTCTG TCGGAGCCGA 
GGGAACCTGA TGGTGCAGAA CAAAAGAAAG AAGAGAAAAA AGAAAAAGAA GGCCCAGGAG 
CAGGGTGTTG CTTTCTCACG TAGCCCTGAG GAGCTGCAGG CCATGTGGTC AGCGCTGGCA 
GAGCGGCTGC TGCAGTGCGC CCAGGAACCT GAGCTCAGTG TGGACTCCAT CATTCCCTTT 
GATGCGGCCT CAGAGGTGCC AGTGGAGGAG CAGCGGGTAG AAGCTATGGT GAGGATCCAA 
GACTGCCTTG TGGCTGGCCA GGCCCCGCAA GCCTTGGCCC TCCTGCGGTC TGCCCGGGAA 
GTGTGGCCTG AAGGAAATGT GTTTGGCTCT CCAGTCATTT CCCCAGGGGA AGAAATGCAG 
TTGCTAAAAC AAATCCTCTC TGCAACCCTT CCCCGGCAGC AAGAGCCAGT AGAAGGAGAT 
GCAGAGGAGG AAGATGAAGA GGAGGAGGAG GAGGAAGAGG AGGAGTTACA GGTGGTCCAG 
GTGTCAGAGA AGGAGTTTAA GTTTTTGGAC TACTTGAAAC GCTTTGCATG CTCAACCATT 
GTGCGAGCCT ATGTGCTTCT CCTGCGGAGC TACCGGCAGA ACAGCGCTCA CACCAACCAC 
TGCATCGCCA AGATGCTGCA CCGGCTGGCC CATGACCTGG GGATGGAAGC CCTGCTTTTC 
CAGCTCTCCC TGTTCTGCCT CTTCAACCAG CTACTCAGTG ACCCAGCCGC TGCAGCCTAC 
AAAGAGCTAG TGACTTTTGC CAAATACATC CTCGGCAAGT TCTTTGCGTT GGCTGCAGTG 
AACCAGAAAG CATTTGTGGA GCTGCTGTTC TGGAAGAACA CCTCGGTGGT TCGGGAAATG 
ACCCAGGGAT ATGGCTCCCT TGACAGTGGG TCTTGCAGCC ACAGAGCCCC TGTGTGGAGC 
TCTGAGGAAG AGGCCCAGCT TCAAGAACTA TACCTCGCCC ACAAGGATGT AGAAGGTCAG 
GATGTAGTGG AGACCATCTT GGCACACCTG AAAGCTGTCC CTCGGACACG CAAGCAGGTC 
ATCCACCATC TGGTACGCAT GGGCCTGGCC GACAGTGTCA AGGACTTCCA GAGGAAAGGG 
ACCCAGATTG TCTTGTGGAC AGAGGATCAG GAGCTGGAGT TACAGCGGCT CTTTGAGGAG 
TTCCAGGATT CCGATGATGT TCTTGGTCAT ATCATGAAGA ATATCACAGC CAAACGTTCA 
CGGGCTCGAG TAGTGGACAA ACTGTTGGCC CTGGGACTCG TGTCCGAGCG CAGGCAACTG 
CACAAGAAAC GGAGGAAGAA GCTGGCGCCC TCTTGCATGC AGAATGGGGA AGAGTCCCAG 
AGAGATGCTT GGCAGGAAGA TCCAGAAGAA GAAGAGGAAA AAGAAGGCTT GCCAGAGAGT 
GAGGGTGAGG AGAACGAGGA AGACTTGTTA GCAGGACAGG TCCAGGGCAG CTCATCTCTT 
TCTGCTGAAA ACCTCCGTCA GAGCCTTTGT CAGGACGGCC TCTCTGCTCC CCTCCTGTGG 
CTCCAGAGCT CCCTGATTCG CGCAGCAGAT GACCGAGAAG AGGATGGCTG CTCCCAGGCC 
ATCCCTCTGG TGCCTCTGAC GGAAGAAAAT GAGGAAGCAA TGGAGAACAA ACAGTTTCAG 
CATCTGCTAC GTAAGCTAGG AATCCGGGCC CCCTGCTCAG GACAGGAAAC CTTCTGGCGA 
ATTCCAGCCA AACTGAGCTC CACCCAGCTT CGGAGAGTGG CTGCTTCTCT GAGTGAGCGA 
GAAAACAAGG AGGAAAGAGA GGAGGAGCCA GAGCCGAATC CAGGAGTCCC TGGAGAGCAG 
AGTCCCAGTG AGGAGCACCA AGTGAGAGCC CCGAGAGCCC TTTTGTCAGC TCGTAAAAGG 
AAAGCAGGCC TGGTGTTTCC AAAAGAGGAG GCCACTGGGG AGGAAGAATG GAAATCGGTG 
CCTAAGAAGC AGCAACTGCT GGACAGCGAC GAAGAGGACA CCGACGACGA GAGGGGAGGG 
CAAGCAGCAG TGTCGGGAAC CCTGAGAATC CACAAGGAGA AACGGTTTCT GGTTGAGGAT 
GAAGATGAGG ATTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_112630.1
CDS	106..3723
Translation	MDLYMMNCELLATCSALGYLEGGTYHKEPDCLESVKDLIRYLRHEDETRDVRQQLGAAQILQSDLLPILTQHRQDKPLFDAVIRLMVNLTQPALLCFGSVPKDPTVRHHFLQVLTYLQAYKEAFASEKAFGVLSETLYELLQLGWEDRQEEDNLLIERILLLVRNILHVPANLEQEKRIDDDASIHDRLLWAIHLSGMDDLLLFLSSSSAEQQWSLHVLEIISLMFRDQKPEQLAGVGQGRLAQERSTDLAELEVLRQREVAEKRARALQRGNRHSRFGGSYVVQGLKSIGERDVVFHKGLHNLQNYSSDLGKQPRRVPKRRQAAQELSVHRRSVLNVRLFLRDFCSEFLENCYNPLMGAVKDHLLREKAQQHDETYYMWAMAFFMAFNRAAAFRPGFVSETLSIRTFHFVEQNLTNYYEMMLTDRKEAASWARRMHLALKAYQELLATVNEMDMCPDDAVRESSRIIKNNIFYMMEYRELFLALFRKFDERYHPRSFLCDLVETTHLFLKMLERFCRSRGNLMVQNKRKKRKKKKKAQEQGVAFSRSPEELQAMWSALAERLLQCAQEPELSVDSIIPFDAASEVPVEEQRVEAMVRIQDCLVAGQAPQALALLRSAREVWPEGNVFGSPVISPGEEMQLLKQILSATLPRQQEPVEGDAEEEDEEEEEEEEEELQVVQVSEKEFKFLDYLKRFACSTIVRAYVLLLRSYRQNSAHTNHCIAKMLHRLAHDLGMEALLFQLSLFCLFNQLLSDPAAAAYKELVTFAKYILGKFFALAAVNQKAFVELLFWKNTSVVREMTQGYGSLDSGSCSHRAPVWSSEEEAQLQELYLAHKDVEGQDVVETILAHLKAVPRTRKQVIHHLVRMGLADSVKDFQRKGTQIVLWTEDQELELQRLFEEFQDSDDVLGHIMKNITAKRSRARVVDKLLALGLVSERRQLHKKRRKKLAPSCMQNGEESQRDAWQEDPEEEEEKEGLPESEGEENEEDLLAGQVQGSSSLSAENLRQSLCQDGLSAPLLWLQSSLIRAADDREEDGCSQAIPLVPLTEENEEAMENKQFQHLLRKLGIRAPCSGQETFWRIPAKLSSTQLRRVAASLSERENKEEREEEPEPNPGVPGEQSPSEEHQVRAPRALLSARKRKAGLVFPKEEATGEEEWKSVPKKQQLLDSDEEDTDDERGGQAAVSGTLRIHKEKRFLVEDEDEDY

Target ORF information:

RefSeq Version	NM_031340.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus timeless circadian regulator (Timeless), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031340.1

ORF Insert Sequence:

ATGGACTTGT ACATGATGAA CTGTGAACTT CTAGCCACTT GTAGCGCCCT TGGGTACTTG 
GAAGGAGGCA CTTACCACAA GGAGCCGGAC TGCTTGGAGA GTGTGAAGGA TTTGATCCGA 
TACCTGAGGC ATGAGGACGA GACTCGAGAT GTGCGGCAGC AGCTGGGAGC CGCGCAGATC 
CTGCAGAGTG ATCTCCTGCC AATCCTCACC CAGCACCGCC AGGACAAGCC TCTCTTTGAT 
GCTGTGATCA GGCTGATGGT AAATTTGACT CAGCCAGCCT TGCTCTGTTT TGGCAGCGTG 
CCTAAGGACC CCACTGTACG ACACCATTTT CTGCAGGTTC TAACCTACCT GCAGGCCTAC 
AAAGAGGCCT TTGCCAGTGA AAAGGCATTT GGAGTCCTCA GCGAAACCTT GTATGAGCTA 
CTGCAGCTGG GCTGGGAGGA TCGGCAAGAA GAAGACAACT TGCTGATTGA ACGGATCCTT 
CTGTTGGTCA GAAATATTCT CCATGTCCCA GCCAACCTTG AGCAGGAGAA GAGGATCGAT 
GACGATGCCA GCATTCATGA CCGGCTTCTG TGGGCAATTC ACCTCAGTGG CATGGACGAC 
TTGCTCCTCT TCCTGTCCAG CTCATCCGCT GAGCAGCAGT GGAGCCTCCA TGTGCTGGAG 
ATCATCTCCC TCATGTTCCG AGACCAGAAG CCTGAGCAGC TGGCAGGAGT AGGGCAGGGA 
CGCTTGGCTC AGGAGCGAAG CACAGATTTG GCAGAATTGG AAGTGCTGCG CCAACGGGAG 
GTGGCCGAGA AGAGAGCCCG AGCCCTGCAG CGAGGAAACA GGCACTCTCG ATTTGGGGGC 
TCCTATGTTG TCCAGGGGTT GAAATCTATT GGGGAGAGGG ATGTCGTCTT TCACAAAGGC 
CTTCACAACC TCCAGAACTA CAGCTCAGAT CTAGGAAAGC AGCCCCGGAG GGTGCCTAAG 
CGTCGTCAGG CTGCCCAGGA GCTGTCTGTC CATCGCCGCT CTGTCCTGAA TGTGAGGCTC 
TTCCTCAGAG ACTTCTGCTC TGAGTTCCTG GAGAACTGTT ACAACCCACT CATGGGTGCA 
GTCAAGGATC ACCTGCTTCG GGAGAAAGCT CAGCAACATG ATGAGACGTA CTACATGTGG 
GCGATGGCTT TCTTTATGGC CTTCAACCGA GCTGCTGCCT TCCGCCCTGG CTTTGTCTCT 
GAGACCCTCA GTATCCGGAC CTTTCACTTT GTGGAGCAGA ACCTCACCAA CTACTATGAG 
ATGATGCTGA CAGACCGCAA GGAGGCCGCC TCCTGGGCAC GCAGGATGCA CCTGGCTCTG 
AAGGCCTATC AGGAGCTGCT GGCCACAGTG AATGAGATGG ACATGTGCCC AGACGACGCT 
GTCAGGGAGA GCAGTCGCAT CATCAAAAAC AACATTTTCT ACATGATGGA GTACCGAGAA 
CTATTTCTGG CACTCTTTCG AAAATTCGAT GAGAGATACC ATCCACGTTC ATTCCTTTGT 
GACCTGGTGG AGACCACTCA CCTCTTCCTC AAAATGTTGG AGCGCTTCTG TCGGAGCCGA 
GGGAACCTGA TGGTGCAGAA CAAAAGAAAG AAGAGAAAAA AGAAAAAGAA GGCCCAGGAG 
CAGGGTGTTG CTTTCTCACG TAGCCCTGAG GAGCTGCAGG CCATGTGGTC AGCGCTGGCA 
GAGCGGCTGC TGCAGTGCGC CCAGGAACCT GAGCTCAGTG TGGACTCCAT CATTCCCTTT 
GATGCGGCCT CAGAGGTGCC AGTGGAGGAG CAGCGGGTAG AAGCTATGGT GAGGATCCAA 
GACTGCCTTG TGGCTGGCCA GGCCCCGCAA GCCTTGGCCC TCCTGCGGTC TGCCCGGGAA 
GTGTGGCCTG AAGGAAATGT GTTTGGCTCT CCAGTCATTT CCCCAGGGGA AGAAATGCAG 
TTGCTAAAAC AAATCCTCTC TGCAACCCTT CCCCGGCAGC AAGAGCCAGT AGAAGGAGAT 
GCAGAGGAGG AAGATGAAGA GGAGGAGGAG GAGGAAGAGG AGGAGTTACA GGTGGTCCAG 
GTGTCAGAGA AGGAGTTTAA GTTTTTGGAC TACTTGAAAC GCTTTGCATG CTCAACCATT 
GTGCGAGCCT ATGTGCTTCT CCTGCGGAGC TACCGGCAGA ACAGCGCTCA CACCAACCAC 
TGCATCGCCA AGATGCTGCA CCGGCTGGCC CATGACCTGG GGATGGAAGC CCTGCTTTTC 
CAGCTCTCCC TGTTCTGCCT CTTCAACCAG CTACTCAGTG ACCCAGCCGC TGCAGCCTAC 
AAAGAGCTAG TGACTTTTGC CAAATACATC CTCGGCAAGT TCTTTGCGTT GGCTGCAGTG 
AACCAGAAAG CATTTGTGGA GCTGCTGTTC TGGAAGAACA CCTCGGTGGT TCGGGAAATG 
ACCCAGGGAT ATGGCTCCCT TGACAGTGGG TCTTGCAGCC ACAGAGCCCC TGTGTGGAGC 
TCTGAGGAAG AGGCCCAGCT TCAAGAACTA TACCTCGCCC ACAAGGATGT AGAAGGTCAG 
GATGTAGTGG AGACCATCTT GGCACACCTG AAAGCTGTCC CTCGGACACG CAAGCAGGTC 
ATCCACCATC TGGTACGCAT GGGCCTGGCC GACAGTGTCA AGGACTTCCA GAGGAAAGGG 
ACCCAGATTG TCTTGTGGAC AGAGGATCAG GAGCTGGAGT TACAGCGGCT CTTTGAGGAG 
TTCCAGGATT CCGATGATGT TCTTGGTCAT ATCATGAAGA ATATCACAGC CAAACGTTCA 
CGGGCTCGAG TAGTGGACAA ACTGTTGGCC CTGGGACTCG TGTCCGAGCG CAGGCAACTG 
CACAAGAAAC GGAGGAAGAA GCTGGCGCCC TCTTGCATGC AGAATGGGGA AGAGTCCCAG 
AGAGATGCTT GGCAGGAAGA TCCAGAAGAA GAAGAGGAAA AAGAAGGCTT GCCAGAGAGT 
GAGGGTGAGG AGAACGAGGA AGACTTGTTA GCAGGACAGG TCCAGGGCAG CTCATCTCTT 
TCTGCTGAAA ACCTCCGTCA GAGCCTTTGT CAGGACGGCC TCTCTGCTCC CCTCCTGTGG 
CTCCAGAGCT CCCTGATTCG CGCAGCAGAT GACCGAGAAG AGGATGGCTG CTCCCAGGCC 
ATCCCTCTGG TGCCTCTGAC GGAAGAAAAT GAGGAAGCAA TGGAGAACAA ACAGTTTCAG 
CATCTGCTAC GTAAGCTAGG AATCCGGGCC CCCTGCTCAG GACAGGAAAC CTTCTGGCGA 
ATTCCAGCCA AACTGAGCTC CACCCAGCTT CGGAGAGTGG CTGCTTCTCT GAGTGAGCGA 
GAAAACAAGG AGGAAAGAGA GGAGGAGCCA GAGCCGAATC CAGGAGTCCC TGGAGAGCAG 
AGTCCCAGTG AGGAGCACCA AGTGAGAGCC CCGAGAGCCC TTTTGTCAGC TCGTAAAAGG 
AAAGCAGGCC TGGTGTTTCC AAAAGAGGAG GCCACTGGGG AGGAAGAATG GAAATCGGTG 
CCTAAGAAGC AGCAACTGCT GGACAGCGAC GAAGAGGACA CCGACGACGA GAGGGGAGGG 
CAAGCAGCAG TGTCGGGAAC CCTGAGAATC CACAAGGAGA AACGGTTTCT GGTTGAGGAT 
GAAGATGAGG ATTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Timeless Interacts with PARP-1 to Promote Homologous Recombination Repair.
Molecular cell60(1)163-76(2015 Oct)
Xie S,Mortusewicz O,Ma HT,Herr P,Poon RY,Poon RR,Helleday T,Qian C

Modulation of ATR-mediated DNA damage checkpoint response by cryptochrome 1.
Nucleic acids research42(7)4427-34(2014 Apr)
Kang TH,Leem SH

Roles of ChlR1 DNA helicase in replication recovery from DNA damage.
Experimental cell research319(14)2244-53(2013 Aug)
Shah N,Inoue A,Woo Lee S,Beishline K,Lahti JM,Noguchi E

Mammalian TIMELESS is involved in period determination and DNA damage-dependent phase advancing of the circadian clock.
PloS one8(2)e56623(2013)
Engelen E,Janssens RC,Yagita K,Smits VA,van der Horst GT,Tamanini F

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Timeless cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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