Cds1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cds1
Entrez Gene ID	81925
Full Name	CDP-diacylglycerol synthase 1
General protein information	Preferred Names CDP-diacylglycerol synthase 1 Names phosphatidate cytidylyltransferase 1 CDP-DAG synthase 1 CDP-DG synthase 1 CDP-DG synthetase 1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 CDP-diglyceride pyrophosphorylase 1 CDP-diglyceride synthase 1 CDP-diglyceride synthetase 1 CDS 1 CTP:phosphatidate cytidylyltransferase 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 14 Map Location: 14p22
Summary	human homolog catalyzes the conversion of phosphatidic acid to CDP-diacylglycerol [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_031242.2	NP_112521.2	phosphatidate cytidylyltransferase 1

Pathways from BioSystems

Homologies

	CDS1	XP_001104375.2
Kluyveromyces lactis	KLLA0F24640g	XP_456177.1
Magnaporthe oryzae (rice blast fungus)	MGG_09371	XP_003720244.1
Pan troglodytes (chimpanzee)	CDS1	XP_517179.2
Bos taurus (cattle)	CDS1	XP_003586270.2
Mus musculus (house mouse)	Cds1	NP_775546.2
Gallus gallus (chicken)	CDS1	XP_420571.4
Drosophila melanogaster (fruit fly)	CdsA	NP_524661.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP007175	XP_308594.4
Caenorhabditis elegans (roundworm)	C33H5.18	NP_501298.1
Schizosaccharomyces pombe (fission yeast)	SPBC13A2.03	NP_596416.1
Oryza sativa (rice)	Os10g0327300	NP_001064355.1
Xenopus tropicalis (tropical clawed frog)	cds1	XP_002937924.1
Eremothecium gossypii	AGOS_AEL084W	NP_984777.1
Neurospora crassa	NCU09643	XP_958709.1
Arabidopsis thaliana (thale cress)	AT4G26770	NP_194407.5
Rattus norvegicus (Norway rat)	Cds1	NP_112521.2
Danio rerio (zebrafish)	cds1	XP_001341899.2
Saccharomyces cerevisiae (baker's yeast)	CDS1	NP_009585.1
Oryza sativa (rice)	Os01g0758400	NP_001044302.1
Homo sapiens (human)	CDS1	NP_001254.2
Canis lupus familiaris (dog)	CDS1	XP_544962.2

Gene Ontology
Bibliography

Related articles in PubMed

Mitochondrial CDP-diacylglycerol synthase activity is due to the peripheral protein, TAMM41 and not due to the integral membrane protein, CDP-diacylglycerol synthase 1.
Blunsom NJ, Gomez-Espinosa E, Ashlin TG, Cockcroft S
Biochimica et biophysica acta1863(3)284-298(2017 Dec)

Isolation and characterization of murine Cds (CDP-diacylglycerol synthase) 1 and 2.
Inglis-Broadgate SL, Ocaka L, Banerjee R, Gaasenbeek M, Chapple JP, Cheetham ME, Clark BJ, Hunt DM, Halford S
Gene35619-31(2005 Aug)

Variants in CHEK2 other than 1100delC do not make a major contribution to breast cancer susceptibility.
Schutte M, Seal S, Barfoot R, Meijers-Heijboer H, Wasielewski M, Evans DG, Eccles D, Meijers C, Lohman F, Klijn J, van den Ouweland A, Futreal PA, Nathanson KL, Weber BL, Easton DF, Stratton MR, Rahman N,
American journal of human genetics72(4)1023-8(2003 Apr)

Mutations in CHEK2 associated with prostate cancer risk.
Dong X, Wang L, Taniguchi K, Wang X, Cunningham JM, McDonnell SK, Qian C, Marks AF, Slager SL, Peterson BJ, Smith DI, Cheville JC, Blute ML, Jacobsen SJ, Schaid DJ, Tindall DJ, Thibodeau SN, Liu W
American journal of human genetics72(2)270-80(2003 Feb)

Mutations of the CHK2 gene are found in some osteosarcomas, but are rare in breast, lung, and ovarian tumors.
Miller CW, Ikezoe T, Krug U, Hofmann WK, Tavor S, Vegesna V, Tsukasaki K, Takeuchi S, Koeffler HP
Genes, chromosomes & cancer33(1)17-21(2002 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Cds1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cds1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa07793	NM_031242.2 Latest version!	Rattus norvegicus CDP-diacylglycerol synthase 1 (Cds1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$272.30 $389.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cds1 ( NM_031242.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_112521.2 Rattus norvegicus CDP-diacylglycerol synthase 1 (Cds1), mRNA.

Price & Availability↑

CloneID	ORa07793
Clone ID Related Accession (Same CDS sequence)	NM_031242.2
Accession Version	NM_031242.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1386bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Rattus norvegicus(Norway rat)
Product	phosphatidate cytidylyltransferase 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC127492.1. On Jun 10, 2007 this sequence version replaced NM_031242.1. ##Evidence-Data-START## Transcript exon combination :: BC127492.1, AB009999.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGCTGGAGC TGCGGCACCG CGGGGGCTGC CCCGGCCCCG GGGGAGCGGG GACGCCGCCA 
CCCCGCGAGG GAGAGGCGGC CGGCGGCGAC CACGAAACCG AGAGCACCAG CGACAAAGAA 
ACAGATATTG ATGACAGGTA TGGAGATCTC GATGCCAGAG GAGATTCCGA TGTTCCTGAG 
GTCCCACCAT CCTCAGACAG GACCCCCGAG ATTCTCAAGA AAGCCCTGTC TGGACTGTCA 
TCAAGATGGA AGAACTGGTG GATTCGTGGG ATCCTCACCC TGACCATGAT CTCCCTCTTC 
TTCCTGATCA TCTATATGGG GTCCTTCATG CTGATGCTTC TGGTTCTGGG CATCCAGGTG 
AAGTGCTTCC AGGAGATCAT AACCATCGGG TACAGGGTCT ACCACTCCTA CGACCTCCCG 
TGGTTTAGAA CACTAAGTTG GTACTTCCTC CTATGTGTGA ACTACTTCTT CTATGGAGAG 
ACAGTGGCAG ATTACTTCGC CACGTTCGTT CAGAGGGAGG AGCAGCTGCA GTTCCTCATT 
CGCTACCACA GGTTCATATC CTTCGCCCTC TACCTGGCAG GTTTCTGCAT GTTCGTCCTG 
AGCTTGGTGA AGAAACACTA CCGACTACAG TTCTATATGT TCGCATGGAC TCACGTCACT 
TTACTGATAA CCGTCACTCA GTCACATCTT GTCATCCAAA ATCTGTTTGA AGGCATGATA 
TGGTTCCTTG TCCCCATATC AAGCGTCATC TGCAATGATA TCACGGCTTA CCTTTTTGGA 
TTTTTTTTTG GAAGAACTCC TTTAATTAAG CTGTCTCCTA AGAAGACCTG GGAAGGATTC 
ATTGGTGGTT TCTTCTCCAC AGTCATATTT GGATTCATTG CTGCCTATGT GTTGTCCAAG 
TATCAGTACT TTGTGTGCCC GGTGGAGTAC CGAAGCGACG TCAACTCCTT CGTGACAGAA 
TGTGAGCCCT CAGAACTGTT CCAGCTTCAG AATTACTCCC TCCCTCCGTT CCTACAGGCA 
GTGCTGAGCC GGGAGACCGT GAGCTTGTAC CCCTTCCAGA TACACAGCAT TGCCCTTTCA 
ACATTTGCAT CACTGATCGG CCCATTCGGA GGCTTCTTCG CCAGTGGATT CAAAAGAGCT 
TTCAAAATCA AGGACTTTGC AAACACTATT CCTGGGCATG GAGGGATAAT GGACAGGTTC 
GATTGTCAGT ATTTGATGGC GACGTTCGTG CACGTGTACA TCACCAGCTT CATCAGGGGT 
CCGAATCCCA GCAAAGTGCT CCAGCAGCTC CTAGTGCTTC AGCCAGAGCA GCAGTTAAAC 
ATCTACAGAA CCCTGAAGAT ACATCTCACG GAGAAAGGCA TCCTGCAGCC CACCTGGAAG 
GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_112521.2
CDS	60..1445
Translation	MLELRHRGGCPGPGGAGTPPPREGEAAGGDHETESTSDKETDIDDRYGDLDARGDSDVPEVPPSSDRTPEILKKALSGLSSRWKNWWIRGILTLTMISLFFLIIYMGSFMLMLLVLGIQVKCFQEIITIGYRVYHSYDLPWFRTLSWYFLLCVNYFFYGETVADYFATFVQREEQLQFLIRYHRFISFALYLAGFCMFVLSLVKKHYRLQFYMFAWTHVTLLITVTQSHLVIQNLFEGMIWFLVPISSVICNDITAYLFGFFFGRTPLIKLSPKKTWEGFIGGFFSTVIFGFIAAYVLSKYQYFVCPVEYRSDVNSFVTECEPSELFQLQNYSLPPFLQAVLSRETVSLYPFQIHSIALSTFASLIGPFGGFFASGFKRAFKIKDFANTIPGHGGIMDRFDCQYLMATFVHVYITSFIRGPNPSKVLQQLLVLQPEQQLNIYRTLKIHLTEKGILQPTWKV

Target ORF information:

RefSeq Version	NM_031242.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus CDP-diacylglycerol synthase 1 (Cds1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031242.2

ORF Insert Sequence:

ATGCTGGAGC TGCGGCACCG CGGGGGCTGC CCCGGCCCCG GGGGAGCGGG GACGCCGCCA 
CCCCGCGAGG GAGAGGCGGC CGGCGGCGAC CACGAAACCG AGAGCACCAG CGACAAAGAA 
ACAGATATTG ATGACAGGTA TGGAGATCTC GATGCCAGAG GAGATTCCGA TGTTCCTGAG 
GTCCCACCAT CCTCAGACAG GACCCCCGAG ATTCTCAAGA AAGCCCTGTC TGGACTGTCA 
TCAAGATGGA AGAACTGGTG GATTCGTGGG ATCCTCACCC TGACCATGAT CTCCCTCTTC 
TTCCTGATCA TCTATATGGG GTCCTTCATG CTGATGCTTC TGGTTCTGGG CATCCAGGTG 
AAGTGCTTCC AGGAGATCAT AACCATCGGG TACAGGGTCT ACCACTCCTA CGACCTCCCG 
TGGTTTAGAA CACTAAGTTG GTACTTCCTC CTATGTGTGA ACTACTTCTT CTATGGAGAG 
ACAGTGGCAG ATTACTTCGC CACGTTCGTT CAGAGGGAGG AGCAGCTGCA GTTCCTCATT 
CGCTACCACA GGTTCATATC CTTCGCCCTC TACCTGGCAG GTTTCTGCAT GTTCGTCCTG 
AGCTTGGTGA AGAAACACTA CCGACTACAG TTCTATATGT TCGCATGGAC TCACGTCACT 
TTACTGATAA CCGTCACTCA GTCACATCTT GTCATCCAAA ATCTGTTTGA AGGCATGATA 
TGGTTCCTTG TCCCCATATC AAGCGTCATC TGCAATGATA TCACGGCTTA CCTTTTTGGA 
TTTTTTTTTG GAAGAACTCC TTTAATTAAG CTGTCTCCTA AGAAGACCTG GGAAGGATTC 
ATTGGTGGTT TCTTCTCCAC AGTCATATTT GGATTCATTG CTGCCTATGT GTTGTCCAAG 
TATCAGTACT TTGTGTGCCC GGTGGAGTAC CGAAGCGACG TCAACTCCTT CGTGACAGAA 
TGTGAGCCCT CAGAACTGTT CCAGCTTCAG AATTACTCCC TCCCTCCGTT CCTACAGGCA 
GTGCTGAGCC GGGAGACCGT GAGCTTGTAC CCCTTCCAGA TACACAGCAT TGCCCTTTCA 
ACATTTGCAT CACTGATCGG CCCATTCGGA GGCTTCTTCG CCAGTGGATT CAAAAGAGCT 
TTCAAAATCA AGGACTTTGC AAACACTATT CCTGGGCATG GAGGGATAAT GGACAGGTTC 
GATTGTCAGT ATTTGATGGC GACGTTCGTG CACGTGTACA TCACCAGCTT CATCAGGGGT 
CCGAATCCCA GCAAAGTGCT CCAGCAGCTC CTAGTGCTTC AGCCAGAGCA GCAGTTAAAC 
ATCTACAGAA CCCTGAAGAT ACATCTCACG GAGAAAGGCA TCCTGCAGCC CACCTGGAAG 
GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mitochondrial CDP-diacylglycerol synthase activity is due to the peripheral protein, TAMM41 and not due to the integral membrane protein, CDP-diacylglycerol synthase 1.
Biochimica et biophysica acta1863(3)284-298(2017 Dec)
Blunsom NJ,Gomez-Espinosa E,Ashlin TG,Cockcroft S

Isolation and characterization of murine Cds (CDP-diacylglycerol synthase) 1 and 2.
Gene35619-31(2005 Aug)
Inglis-Broadgate SL,Ocaka L,Banerjee R,Gaasenbeek M,Chapple JP,Cheetham ME,Clark BJ,Hunt DM,Halford S

Variants in CHEK2 other than 1100delC do not make a major contribution to breast cancer susceptibility.
American journal of human genetics72(4)1023-8(2003 Apr)
Schutte M,Seal S,Barfoot R,Meijers-Heijboer H,Wasielewski M,Evans DG,Eccles D,Meijers C,Lohman F,Klijn J,van den Ouweland A,Futreal PA,Nathanson KL,Weber BL,Easton DF,Stratton MR,Rahman N,

Mutations in CHEK2 associated with prostate cancer risk.
American journal of human genetics72(2)270-80(2003 Feb)
Dong X,Wang L,Taniguchi K,Wang X,Cunningham JM,McDonnell SK,Qian C,Marks AF,Slager SL,Peterson BJ,Smith DI,Cheville JC,Blute ML,Jacobsen SJ,Schaid DJ,Tindall DJ,Thibodeau SN,Liu W

Mutations of the CHK2 gene are found in some osteosarcomas, but are rare in breast, lung, and ovarian tumors.
Genes, chromosomes & cancer33(1)17-21(2002 Jan)
Miller CW,Ikezoe T,Krug U,Hofmann WK,Tavor S,Vegesna V,Tsukasaki K,Takeuchi S,Koeffler HP

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Cds1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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