Rab11a cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Rab11a
Entrez Gene ID	81830
Full Name	RAB11a, member RAS oncogene family
General protein information	Preferred Names RAB11a, member RAS oncogene family Names ras-related protein Rab-11A 24KG rab-11
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 8 Map Location: 8q24
Summary	GTP-binding protein [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_031152.2	NP_112414.1	ras-related protein Rab-11A

Pathways from BioSystems

Homologies

Homo sapiens (human)	RAB11A	NP_004654.1
Rattus norvegicus (Norway rat)	Rab11a	NP_112414.1
Gallus gallus (chicken)	RAB11A	NP_001005827.1
Caenorhabditis elegans (roundworm)	rab-11.1	NP_490675.1
Schizosaccharomyces pombe (fission yeast)	ypt3	NP_593667.1
Neurospora crassa	NCU01523	XP_956972.2
Arabidopsis thaliana (thale cress)	RABA1f	NP_200894.1
Oryza sativa (rice)	Os05g0564400	NP_001056333.1
Xenopus tropicalis (tropical clawed frog)	rab11a	NP_001016481.1
Pan troglodytes (chimpanzee)	RAB11A	XP_510490.2
Mus musculus (house mouse)	Rab11a	NP_059078.2
Arabidopsis thaliana (thale cress)	RABA1g	NP_188124.1
	RAB11A	XP_001103732.2
Bos taurus (cattle)	RAB11A	NP_001033251.1
Eremothecium gossypii	AGOS_AER434C	NP_985289.2
Canis lupus familiaris (dog)	RAB11A	NP_001003276.1
Drosophila melanogaster (fruit fly)	Rab11	NP_477170.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004559	XP_001238825.3
Saccharomyces cerevisiae (baker's yeast)	YPT31	NP_010948.1
Kluyveromyces lactis	KLLA0B00671g	XP_451560.2
Danio rerio (zebrafish)	rab11a	NP_001007360.1
Magnaporthe oryzae (rice blast fungus)	MGG_01079	XP_003717859.1
Oryza sativa (rice)	Os09g0327100	NP_001062887.2

Gene Ontology
Bibliography

Related articles in PubMed

Characterization of Heparan Sulfate Proteoglycan-positive Recycling Endosomes Isolated from Glioma Cells.
Podyma-Inoue KA, Moriwaki T, Rajapakshe AR, Terasawa K, Hara-Yokoyama M
Cancer genomics & proteomics13(6)443-452(2016 11-12)

Selective rab11 transport and the intrinsic regenerative ability of CNS axons.
Koseki H, Doneg? M, Lam BY, Petrova V, van Erp S, Yeo GS, Kwok JC, Ffrench-Constant C, Eva R, Fawcett JW
eLife6(2017 Aug)

Rab8a/Rab11a regulate intercellular communications between neural cells via tunneling nanotubes.
Zhu H, Xue C, Xu X, Guo Y, Li X, Lu J, Ju S, Wang Y, Cao Z, Gu X
Cell death & disease7(12)e2523(2016 Dec)

Exclusive expression of the Rab11 effector SH3TC2 in Schwann cells links integrin-?6 and myelin maintenance to Charcot-Marie-Tooth disease type 4C.
Vijay S, Chiu M, Dacks JB, Roberts RC
Biochimica et biophysica acta1862(7)1279-90(2016 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

the Heparan sulfate proteoglycans-positive vesicular fractions, distinct from plasma membrane-derived material, were enriched in endocytic marker, Rab11.
Title: Characterization of Heparan Sulfate Proteoglycan-positive Recycling Endosomes Isolated from Glioma Cells.

Rab8a or Rab11a might be involved in the formation of tunneling nanotubes structures in the peripheral nerve system.
Title: Rab8a/Rab11a regulate intercellular communications between neural cells via tunneling nanotubes.

miR-21 inhibited autophagy by targeting the Rab11a 3'UTR in renal ischemia reperfusion injury.
Title: MiR-21 inhibits autophagy by targeting Rab11a in renal ischemia/reperfusion.

Data indicate that internalized dopamine transporter (DAT) colocalized with GFP-Rab11 and suggest that Rab11 plays an important role in the recycling of DAT following AMPH-induced DAT down-regulation.
Title: Differential targeting of the dopamine transporter to recycling or degradative pathways during amphetamine- or PKC-regulated endocytosis in dopamine neurons.

Results indicate that Rab11a, Rab8a, and Myo5B function as part of a network to promote stretch-induced exocytosis.
Title: A Rab11a-Rab8a-Myo5B network promotes stretch-regulated exocytosis in bladder umbrella cells.

The following Rab11a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rab11a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa07766	NM_031152.2 Latest version!	Rattus norvegicus RAB11a, member RAS oncogene family (Rab11a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Rab11a ( NM_031152.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_112414.1 Rattus norvegicus RAB11a, member RAS oncogene family (Rab11a), mRNA.

Price & Availability↑

CloneID	ORa07766
Clone ID Related Accession (Same CDS sequence)	NM_031152.2
Accession Version	NM_031152.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 651bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-14
Organism	Rattus norvegicus(Norway rat)
Product	ras-related protein Rab-11A
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC085727.1. On Nov 15, 2004 this sequence version replaced NM_031152.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC085727.1, FQ220297.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGGCACCC GCGACGACGA GTACGACTAC CTCTTTAAAG TTGTCCTTAT TGGAGATTCT 
GGTGTTGGGA AGAGTAACCT CCTGTCTCGA TTTACTCGGA ATGAGTTTAA TCTGGAAAGC 
AAGAGTACCA TTGGAGTAGA ATTTGCAACA AGAAGCATCC AGGTTGATGG GAAAACAATA 
AAGGCACAGA TATGGGACAC AGCAGGGCAG GAGCGGTACA GGGCTATAAC GTCTGCATAC 
TATCGTGGAG CAGTAGGTGC CTTATTGGTT TATGACATTG CTAAGCATCT CACATATGAA 
AATGTAGAAC GATGGCTGAA AGAACTGAGA GATCATGCTG ATAGTAACAT TGTTATCATG 
CTTGTGGGCA ATAAGAGTGA TTTACGTCAT CTCAGGGCAG TTCCTACAGA TGAAGCAAGA 
GCATTTGCAG AGAAGAATGG TTTGTCGTTC ATTGAGACAT CTGCTCTAGA TTCTACAAAT 
GTTGAAGCTG CTTTTCAGAC AATTCTAACA GAGATATACC GCATTGTTTC TCAGAAGCAA 
ATGTCAGACA GACGTGAAAA TGACATGTCT CCAAGCAACA ATGTGGTTCC TATTCATGTC 
CCACCCACCA CTGAGAACAA GCCAAAGGTG CAGTGCTGTC AGAACATCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_112414.1
CDS	66..716
Translation	MGTRDDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNGLSFIETSALDSTNVEAAFQTILTEIYRIVSQKQMSDRRENDMSPSNNVVPIHVPPTTENKPKVQCCQNI

Target ORF information:

RefSeq Version	NM_031152.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus RAB11a, member RAS oncogene family (Rab11a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031152.2

ORF Insert Sequence:

ATGGGCACCC GCGACGACGA GTACGACTAC CTCTTTAAAG TTGTCCTTAT TGGAGATTCT 
GGTGTTGGGA AGAGTAACCT CCTGTCTCGA TTTACTCGGA ATGAGTTTAA TCTGGAAAGC 
AAGAGTACCA TTGGAGTAGA ATTTGCAACA AGAAGCATCC AGGTTGATGG GAAAACAATA 
AAGGCACAGA TATGGGACAC AGCAGGGCAG GAGCGGTACA GGGCTATAAC GTCTGCATAC 
TATCGTGGAG CAGTAGGTGC CTTATTGGTT TATGACATTG CTAAGCATCT CACATATGAA 
AATGTAGAAC GATGGCTGAA AGAACTGAGA GATCATGCTG ATAGTAACAT TGTTATCATG 
CTTGTGGGCA ATAAGAGTGA TTTACGTCAT CTCAGGGCAG TTCCTACAGA TGAAGCAAGA 
GCATTTGCAG AGAAGAATGG TTTGTCGTTC ATTGAGACAT CTGCTCTAGA TTCTACAAAT 
GTTGAAGCTG CTTTTCAGAC AATTCTAACA GAGATATACC GCATTGTTTC TCAGAAGCAA 
ATGTCAGACA GACGTGAAAA TGACATGTCT CCAAGCAACA ATGTGGTTCC TATTCATGTC 
CCACCCACCA CTGAGAACAA GCCAAAGGTG CAGTGCTGTC AGAACATCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Characterization of Heparan Sulfate Proteoglycan-positive Recycling Endosomes Isolated from Glioma Cells.
Cancer genomics & proteomics13(6)443-452(2016 11-12)
Podyma-Inoue KA,Moriwaki T,Rajapakshe AR,Terasawa K,Hara-Yokoyama M

Selective rab11 transport and the intrinsic regenerative ability of CNS axons.
eLife6(2017 Aug)
Koseki H,Doneg? M,Lam BY,Petrova V,van Erp S,Yeo GS,Kwok JC,Ffrench-Constant C,Eva R,Fawcett JW

Rab8a/Rab11a regulate intercellular communications between neural cells via tunneling nanotubes.
Cell death & disease7(12)e2523(2016 Dec)
Zhu H,Xue C,Xu X,Guo Y,Li X,Lu J,Ju S,Wang Y,Cao Z,Gu X

Exclusive expression of the Rab11 effector SH3TC2 in Schwann cells links integrin-?6 and myelin maintenance to Charcot-Marie-Tooth disease type 4C.
Biochimica et biophysica acta1862(7)1279-90(2016 Jul)
Vijay S,Chiu M,Dacks JB,Roberts RC

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Rab11a cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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