Snrpn cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Snrpn
Entrez Gene ID	81781
Full Name	small nuclear ribonucleoprotein polypeptide N
Synonyms	FE 294,FE 294 psi,FE294,FE294 psi
General protein information	Preferred Names small nuclear ribonucleoprotein polypeptide N Names small nuclear ribonucleoprotein-associated protein N FE294 gene for snRNP-associated polypeptide N FE294 psi pseudogene sm protein D sm protein N sm-D sm-N smN small nuclear ribonucleoparticle-associated protein (snRNP) mRNA, clone Sm51 small nuclear ribonucleoprotein N snRNP-N
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q36
Summary	component of the small nuclear ribonucleoprotein (snRNP) complex; may be involved in tissue-specific alternative RNA processing events, such as pre-mRNA splicing [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_031117.2	NP_112379.1	small nuclear ribonucleoprotein-associated protein N

Pathways from BioSystems

Homologies

	SNRPN	XP_001108013.1
Mus musculus (house mouse)	Snrpn	NP_001076430.1
Xenopus tropicalis (tropical clawed frog)	snrpb	NP_001001198.1
Homo sapiens (human)	SNRPN	NP_003088.1
Rattus norvegicus (Norway rat)	Snrpn	NP_112379.1
Gallus gallus (chicken)	SNRPB	NP_989930.1
Drosophila melanogaster (fruit fly)	SmB	NP_001188780.1
Caenorhabditis elegans (roundworm)	snr-2	NP_493348.1
Pan troglodytes (chimpanzee)	SNRPN	NP_001243726.1
Danio rerio (zebrafish)	snrpb	NP_991230.1
Canis lupus familiaris (dog)	SNRPN	XP_005618293.1
Bos taurus (cattle)	SNRPN	NP_001073265.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP005523	XP_315523.4

Gene Ontology
Bibliography

Related articles in PubMed

Effects of varicocele on DNA methylation pattern of H19 and Snrpn gene in spermatozoa and behavioural characteristics of adult rat offspring.
Zhang Q, Zhang F, Gao HH, Zhang JM
Andrologia49(1)(2017 Feb)

Small nuclear ribonucleoprotein polypeptide N (Sm51) promotes osteogenic differentiation of bone marrow mesenchymal stem cells by regulating Runx2.
Meng F, Xu L, Huang S, Liu Y, Hou Y, Wang K, Jiang X, Li G
Cell and tissue research366(1)155-62(2016 10)

Deletion of small nuclear ribonucleoprotein polypeptide N (SNRPN) in Prader-Willi syndrome detected by fluorescence in situ hybridization: two sibs with the typical phenotype without a cytogenetic deletion in chromosome 15q.
Ishikawa T, Kibe T, Wada Y
American journal of medical genetics62(4)350-2(1996 Apr)

The snRNP core protein SmB and tissue-specific SmN protein are differentially distributed between snRNP particles.
Huntriss JD, Latchman DS, Williams DG
Nucleic acids research21(17)4047-53(1993 Aug)

Isolation and structural characterization of the rat gene encoding the brain specific snRNP-associated polypeptide "N".
Esposito F, Fiore F, Cimino F, Russo T
Biochemical and biophysical research communications195(1)317-26(1993 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Varicocele does not alter the methylation profiles of H19 and Snrpn gene, but exerts depressant-like effect on the adult rat offspring.
Title: Effects of varicocele on DNA methylation pattern of H19 and Snrpn gene in spermatozoa and behavioural characteristics of adult rat offspring.

Sm51 plays an important role in regulating osteogenic differentiation of mesenchymal stem cells through increasing Runx2 expression
Title: Small nuclear ribonucleoprotein polypeptide N (Sm51) promotes osteogenic differentiation of bone marrow mesenchymal stem cells by regulating Runx2.

The following Snrpn gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Snrpn cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa07650	NM_031117.2 Latest version!	Rattus norvegicus small nuclear ribonucleoprotein polypeptide N (Snrpn), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Snrpn ( NM_031117.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_112379.1 Rattus norvegicus small nuclear ribonucleoprotein polypeptide N (Snrpn), mRNA.

Price & Availability↑

CloneID	ORa07650
Clone ID Related Accession (Same CDS sequence)	NM_031117.2
Accession Version	NM_031117.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 723bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Rattus norvegicus(Norway rat)
Product	small nuclear ribonucleoprotein-associated protein N
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07005711.1, FM122235.1 and BC087671.1. On Jul 27, 2012 this sequence version replaced NM_031117.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M29293.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACTGTGG GTAAGAGTAG CAAGATGCTC CAGCATATTG ACTATAGAAT GAGATGTATC 
CTGCAAGATG GAAGAATCTT CATTGGCACC TTTAAGGCTT TTGACAAGCA TATGAATTTG 
ATCCTCTGTG ATTGTGATGA GTTCAGGAAG ATCAAGCCAA AGAATGCAAA ACAGCCAGAA 
CGTGAAGAAA AACGGGTTTT GGGTCTGGTC TTGCTACGTG GAGAGAACTT GGTTTCCATG 
ACAGTGGAGG GTCCACCTCC TAAAGATACT GGCATTGCTC GTGTGCCACT TGCTGGTGCT 
GCAGGTGGCC CTGGTGTTGG AAGAGCAGCT GGCAGAGGAG TACCAGCAGG TGTACCTATT 
CCCCAAGCTC CTGCTGGATT AGCAGGCCCT GTCCGAGGAG TTGGAGGCCC ATCCCAGCAG 
GTCATGACCC CACAGGGAAG AGGCACTGTT GCAGCTGCTG CTGTTGCTGC TACTGCTAGC 
ATTGCAGGAG CCCCAACCCA GTACCCGCCA GGACGGGGAA CTCCACCTCC ACCTGTAGGC 
AGAGCAACCC CACCTCCAGG CATTATGGCT CCTCCACCTG GAATGAGACC ACCCATGGGC 
CCACCAATTG GACTTCCCCC TGCTCGAGGG ACACCTATAG GCATGCCCCC TCCAGGAATG 
AGACCCCCTC CTCCAGGAAT TAGAGGCCCA CCTCCCCCAG GAATGCGTCC ACCAAGACCC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_112379.1
CDS	597..1319
Translation	MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPEREEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPPPGMRPPRP

Target ORF information:

RefSeq Version	NM_031117.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus small nuclear ribonucleoprotein polypeptide N (Snrpn), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031117.2

ORF Insert Sequence:

ATGACTGTGG GTAAGAGTAG CAAGATGCTC CAGCATATTG ACTATAGAAT GAGATGTATC 
CTGCAAGATG GAAGAATCTT CATTGGCACC TTTAAGGCTT TTGACAAGCA TATGAATTTG 
ATCCTCTGTG ATTGTGATGA GTTCAGGAAG ATCAAGCCAA AGAATGCAAA ACAGCCAGAA 
CGTGAAGAAA AACGGGTTTT GGGTCTGGTC TTGCTACGTG GAGAGAACTT GGTTTCCATG 
ACAGTGGAGG GTCCACCTCC TAAAGATACT GGCATTGCTC GTGTGCCACT TGCTGGTGCT 
GCAGGTGGCC CTGGTGTTGG AAGAGCAGCT GGCAGAGGAG TACCAGCAGG TGTACCTATT 
CCCCAAGCTC CTGCTGGATT AGCAGGCCCT GTCCGAGGAG TTGGAGGCCC ATCCCAGCAG 
GTCATGACCC CACAGGGAAG AGGCACTGTT GCAGCTGCTG CTGTTGCTGC TACTGCTAGC 
ATTGCAGGAG CCCCAACCCA GTACCCGCCA GGACGGGGAA CTCCACCTCC ACCTGTAGGC 
AGAGCAACCC CACCTCCAGG CATTATGGCT CCTCCACCTG GAATGAGACC ACCCATGGGC 
CCACCAATTG GACTTCCCCC TGCTCGAGGG ACACCTATAG GCATGCCCCC TCCAGGAATG 
AGACCCCCTC CTCCAGGAAT TAGAGGCCCA CCTCCCCCAG GAATGCGTCC ACCAAGACCC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Effects of varicocele on DNA methylation pattern of H19 and Snrpn gene in spermatozoa and behavioural characteristics of adult rat offspring.
Andrologia49(1)(2017 Feb)
Zhang Q,Zhang F,Gao HH,Zhang JM

Small nuclear ribonucleoprotein polypeptide N (Sm51) promotes osteogenic differentiation of bone marrow mesenchymal stem cells by regulating Runx2.
Cell and tissue research366(1)155-62(2016 10)
Meng F,Xu L,Huang S,Liu Y,Hou Y,Wang K,Jiang X,Li G

Deletion of small nuclear ribonucleoprotein polypeptide N (SNRPN) in Prader-Willi syndrome detected by fluorescence in situ hybridization: two sibs with the typical phenotype without a cytogenetic deletion in chromosome 15q.
American journal of medical genetics62(4)350-2(1996 Apr)
Ishikawa T,Kibe T,Wada Y

The snRNP core protein SmB and tissue-specific SmN protein are differentially distributed between snRNP particles.
Nucleic acids research21(17)4047-53(1993 Aug)
Huntriss JD,Latchman DS,Williams DG

Isolation and structural characterization of the rat gene encoding the brain specific snRNP-associated polypeptide "N".
Biochemical and biophysical research communications195(1)317-26(1993 Aug)
Esposito F,Fiore F,Cimino F,Russo T

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Snrpn cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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