Sctr cDNA ORF clone, Rattus norvegicus(Norway rat)

Structure and Function of Cross-class Complexes of G Protein-coupled Secretin and Angiotensin 1a Receptors.
Harikumar KG, Augustine ML, Lee LT, Chow BK, Miller LJ
The Journal of biological chemistry291(33)17332-44(2016 08)

Lipolytic actions of secretin in mouse adipocytes.
Sekar R, Chow BK
Journal of lipid research55(2)190-200(2014 Feb)

MTR120/KIAA1383, a novel microtubule-associated protein, promotes microtubule stability and ensures cytokinesis.
Fong KW, Leung JW, Li Y, Wang W, Feng L, Ma W, Liu D, Songyang Z, Chen J
Journal of cell science126(Pt 3)825-37(2013 Feb)

Secretin receptor promotes the proliferation of endocrine tumor cells via the PI3K/AKT pathway.
Lee M, Waser B, Reubi JC, Pellegata NS
Molecular endocrinology (Baltimore, Md.)26(8)1394-405(2012 Aug)

Structure and Function of Cross-class Complexes of G Protein-coupled Secretin and Angiotensin 1a Receptors.
Title: Structure and Function of Cross-class Complexes of G Protein-coupled Secretin and Angiotensin 1a Receptors.

Secretin receptors are overexpressed in various endocrine tumor cells and play a proproliferative role in pheochromocytoma and adrenocortical carcinoma cells.
Title: Secretin receptor promotes the proliferation of endocrine tumor cells via the PI3K/AKT pathway.

Molecular basis of secretin docking to its intact receptor using multiple photolabile probes distributed throughout the pharmacophore.
Title: Molecular basis of secretin docking to its intact receptor using multiple photolabile probes distributed throughout the pharmacophore.

Data show that in secretin/secretin receptor binding, the alpha-helix in natural secretin was oriented approximately parallel to the amino-terminal alpha-helix of the receptor.
Title: Importance of each residue within secretin for receptor binding and biological activity.

Model of helical bundle and loop domains of prototypic secretin receptor is consistent with endogenous agonist mechanism for class II G-protein-coupled receptor activation, where ligand binding promotes interaction of a portion of receptor amino terminus.
Title: Spatial approximation between secretin residue five and the third extracellular loop of its receptor provides new insight into the molecular basis of natural agonist binding.