Rala cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Rala
Entrez Gene ID	81757
Full Name	RAS like proto-oncogene A
General protein information	Preferred Names RAS like proto-oncogene A Names ras-related protein Ral-A -ral simian leukemia viral oncogene homolog A (ras related) RALA Ras like proto-oncogene A v-ral simian leukemia viral oncogene homolog A (ras related)
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 17 Map Location: 17q11
Summary	putative GTP binding protein [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_031093.2	NP_112355.1	ras-related protein Ral-A precursor
XM_006253993.3	XP_006254055.1	ras-related protein Ral-A isoform X1
XM_017600665.1	XP_017456154.1	ras-related protein Ral-A isoform X1
XM_017600664.1	XP_017456153.1	ras-related protein Ral-A isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	RALA	XP_001140368.1
Bos taurus (cattle)	RALA	NP_001029816.1
Drosophila melanogaster (fruit fly)	Rala	NP_726882.1
Xenopus tropicalis (tropical clawed frog)	rala	NP_001015915.1
Homo sapiens (human)	RALA	NP_005393.2
Caenorhabditis elegans (roundworm)	ral-1	NP_001254866.1
Mus musculus (house mouse)	Rala	NP_062364.3
Rattus norvegicus (Norway rat)	Rala	NP_112355.1
Gallus gallus (chicken)	RALA	XP_004939621.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012108	XP_320421.3
	RALA	XP_001099131.1
Canis lupus familiaris (dog)	RALA	XP_533083.2
Danio rerio (zebrafish)	ralaa	NP_957312.1

Gene Ontology
Bibliography

Related articles in PubMed

Dysregulation of KRAS signaling in pancreatic cancer is not associated with
Lemstrova R, Brynychova V, Hughes DJ, Hlavac V, Dvorak P, Doherty JE, Murray HA, Crockard M, Oliverius M, Hlavsa J, Honsova E, Mazanec J, Kala Z, Lovecek M, Havlik R, Ehrmann J, Strouhal O, Soucek P, Melichar B, Mohelnikova-Duchonova B
Oncology letters14(5)5980-5988(2017 Nov)

Longest neurite-specific activation of Rap1B in hippocampal neurons contributes to polarity formation through RalA and Nore1A in addition to PI3-kinase.
Nakamura T, Yasuda S, Nagai H, Koinuma S, Morishita S, Goto A, Kinashi T, Wada N
Genes to cells : devoted to molecular & cellular mechanisms18(11)1020-31(2013 Nov)

The deubiquitylase USP33 discriminates between RALB functions in autophagy and innate immune response.
Simicek M, Lievens S, Laga M, Guzenko D, Aushev VN, Kalev P, Baietti MF, Strelkov SV, Gevaert K, Tavernier J, Sablina AA
Nature cell biology15(10)1220-30(2013 Oct)

RalA GTPase tethers insulin granules to L- and R-type calcium channels through binding ?2 ?-1 subunit.
Xie L, Kang Y, Liang T, Dolai S, Xie H, Parsaud L, Lopez JA, He Y, Chidambaram S, Lam PP, James DE, Sugita S, Gaisano HY
Traffic (Copenhagen, Denmark)14(4)428-39(2013 Apr)

Genetic deletion of RALA and RALB small GTPases reveals redundant functions in development and tumorigenesis.
Peschard P, McCarthy A, Leblanc-Dominguez V, Yeo M, Guichard S, Stamp G, Marshall CJ
Current biology : CB22(21)2063-8(2012 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

specific activation of Rap1B contributes to neuronal polarization via interaction with RalA and Nore1A in addition to PI3-kinase.
Title: Longest neurite-specific activation of Rap1B in hippocampal neurons contributes to polarity formation through RalA and Nore1A in addition to PI3-kinase.

RalA modulates insulin release by binding to auxiliary calcium channel subunits on the insulin granules.
Title: RalA GTPase tethers insulin granules to L- and R-type calcium channels through binding ?2 ?-1 subunit.

RalA plays a pivotal role also in Rac1-mediated GLUT4 translocation in muscle cells.
Title: Role of RalA downstream of Rac1 in insulin-dependent glucose uptake in muscle cells.

Demonstrated that the PH-PxxP domain of RalGPS2 inhibits RalA activation inducing PC12 differentiation redirecting NGF signal to MAPK pathway, and that this domain is involved in the actin remodelling which is necessary for neurites elongation.
Title: The PH-PxxP domain of RalGPS2 promotes PC12 cells differentiation acting as a dominant negative for RalA GTPase activation.

RalA activation elicited by the exchange factor RalGDS in response to a rise in intracellular Ca2+ and cAMP controls hormone release from pancreatic beta-cells
Title: The GTPase RalA regulates different steps of the secretory process in pancreatic beta-cells.

The following Rala gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rala cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa07575	NM_031093.2 Latest version!	Rattus norvegicus RAS like proto-oncogene A (Rala), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
ORa37913	XM_017600664.1 Latest version!	Rattus norvegicus RALA Ras like proto-oncogene A (Rala), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa37913	XM_017600665.1 Latest version!	Rattus norvegicus RALA Ras like proto-oncogene A (Rala), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa37913	XM_006253993.3 Latest version!	Rattus norvegicus RALA Ras like proto-oncogene A (Rala), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Rala ( NM_031093.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_112355.1 Rattus norvegicus RAS like proto-oncogene A (Rala), mRNA.

Price & Availability↑

CloneID	ORa07575
Clone ID Related Accession (Same CDS sequence)	NM_031093.2
Accession Version	NM_031093.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 621bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-07
Organism	Rattus norvegicus(Norway rat)
Product	ras-related protein Ral-A precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from L19698.1. On Oct 9, 2003 this sequence version replaced NM_031093.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGCTGCAA ACAAGCCCAA GGGTCAGAAT TCTTTGGCCT TACACAAAGT CATCATGGTG 
GGCAGTGGTG GTGTGGGCAA GTCTGCTCTG ACTCTGCAGT TCATGTATGA TGAGTTTGTA 
GAAGACTATG AACCTACCAA AGCAGACAGC TACAGGAAGA AGGTAGTGCT GGATGGGGAG 
GAAGTGCAGA TCGACATCTT AGATACAGCA GGGCAGGAAG ACTACGCTGC AATTAGAGAC 
AACTACTTCC GAAGTGGGGA AGGATTCCTC TGTGTCTTCT CTATCACAGA GATGGAGTCC 
TTTGCAGCTA CAGCGGACTT CAGGGAACAG ATTTTAAGAG TAAAAGAAGA TGAGAATGTC 
CCATTTCTCC TGGTTGGTAA CAAATCAGAT TTAGAAGATA AAAGGCAGGT TTCTGTAGAA 
GAGGCAAAAA ACAGAGCTGA CCAGTGGAAC GTTAACTATG TGGAGACGTC TGCTAAAACG 
CGCGCCAACG TTGACAAGGT ATTTTTTGAT TTAATGAGGG AAATACGAGC CAGAAAGATG 
GAAGACAGCA AAGAAAAAAA TGGAAAAAAG AAGAGGAAAA GTTTAGCCAA GAGAATCAGA 
GAAAGATGCT GCATTTTATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_112355.1
CDS	37..657
Translation	MAANKPKGQNSLALHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILRVKEDENVPFLLVGNKSDLEDKRQVSVEEAKNRADQWNVNYVETSAKTRANVDKVFFDLMREIRARKMEDSKEKNGKKKRKSLAKRIRERCCIL

Target ORF information:

RefSeq Version	NM_031093.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus RAS like proto-oncogene A (Rala), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031093.2

ORF Insert Sequence:

ATGGCTGCAA ACAAGCCCAA GGGTCAGAAT TCTTTGGCCT TACACAAAGT CATCATGGTG 
GGCAGTGGTG GTGTGGGCAA GTCTGCTCTG ACTCTGCAGT TCATGTATGA TGAGTTTGTA 
GAAGACTATG AACCTACCAA AGCAGACAGC TACAGGAAGA AGGTAGTGCT GGATGGGGAG 
GAAGTGCAGA TCGACATCTT AGATACAGCA GGGCAGGAAG ACTACGCTGC AATTAGAGAC 
AACTACTTCC GAAGTGGGGA AGGATTCCTC TGTGTCTTCT CTATCACAGA GATGGAGTCC 
TTTGCAGCTA CAGCGGACTT CAGGGAACAG ATTTTAAGAG TAAAAGAAGA TGAGAATGTC 
CCATTTCTCC TGGTTGGTAA CAAATCAGAT TTAGAAGATA AAAGGCAGGT TTCTGTAGAA 
GAGGCAAAAA ACAGAGCTGA CCAGTGGAAC GTTAACTATG TGGAGACGTC TGCTAAAACG 
CGCGCCAACG TTGACAAGGT ATTTTTTGAT TTAATGAGGG AAATACGAGC CAGAAAGATG 
GAAGACAGCA AAGAAAAAAA TGGAAAAAAG AAGAGGAAAA GTTTAGCCAA GAGAATCAGA 
GAAAGATGCT GCATTTTATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rala ( XM_006253993.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006254055.1 Rattus norvegicus RALA Ras like proto-oncogene A (Rala), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa37913
Clone ID Related Accession (Same CDS sequence)	XM_006253993.3 , XM_017600665.1 , XM_017600664.1
Accession Version	XM_006253993.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 621bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	ras-related protein Ral-A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005116.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006253993.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGCAA ACAAGCCCAA GGGTCAGAAT TCTTTGGCCT TACACAAAGT CATCATGGTG 
GGCAGTGGTG GTGTGGGCAA GTCTGCTCTG ACTCTGCAGT TCATGTATGA TGAGTTTGTA 
GAAGACTATG AACCTACCAA AGCAGACAGC TACAGGAAGA AGGTAGTGCT GGATGGGGAG 
GAAGTGCAGA TCGACATCTT AGATACAGCA GGGCAGGAAG ACTACGCTGC AATTAGAGAC 
AACTACTTCC GAAGTGGGGA GGGATTCCTC TGTGTCTTCT CTATCACAGA GATGGAGTCC 
TTTGCAGCTA CAGCGGACTT CAGGGAACAG ATTTTAAGAG TAAAAGAAGA TGAGAATGTC 
CCATTTCTCC TGGTTGGTAA CAAATCAGAT TTAGAAGATA AAAGGCAGGT TTCTGTAGAA 
GAGGCAAAAA ACAGAGCTGA CCAGTGGAAC GTTAACTATG TGGAGACGTC TGCTAAAACG 
CGCGCCAACG TTGACAAGGT ATTTTTTGAT TTAATGAGGG AAATACGAGC CAGAAAGATG 
GAAGACAGCA AAGAAAAAAA TGGAAAAAAG AAGAGGAAAA GTTTAGCCAA GAGAATCAGA 
GAAAGATGCT GCATTTTATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006254055.1
CDS	250..870
Translation	MAANKPKGQNSLALHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILRVKEDENVPFLLVGNKSDLEDKRQVSVEEAKNRADQWNVNYVETSAKTRANVDKVFFDLMREIRARKMEDSKEKNGKKKRKSLAKRIRERCCIL

Target ORF information:

RefSeq Version	XM_006253993.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus RALA Ras like proto-oncogene A (Rala), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006253993.3

ORF Insert Sequence:

ATGGCTGCAA ACAAGCCCAA GGGTCAGAAT TCTTTGGCCT TACACAAAGT CATCATGGTG 
GGCAGTGGTG GTGTGGGCAA GTCTGCTCTG ACTCTGCAGT TCATGTATGA TGAGTTTGTA 
GAAGACTATG AACCTACCAA AGCAGACAGC TACAGGAAGA AGGTAGTGCT GGATGGGGAG 
GAAGTGCAGA TCGACATCTT AGATACAGCA GGGCAGGAAG ACTACGCTGC AATTAGAGAC 
AACTACTTCC GAAGTGGGGA GGGATTCCTC TGTGTCTTCT CTATCACAGA GATGGAGTCC 
TTTGCAGCTA CAGCGGACTT CAGGGAACAG ATTTTAAGAG TAAAAGAAGA TGAGAATGTC 
CCATTTCTCC TGGTTGGTAA CAAATCAGAT TTAGAAGATA AAAGGCAGGT TTCTGTAGAA 
GAGGCAAAAA ACAGAGCTGA CCAGTGGAAC GTTAACTATG TGGAGACGTC TGCTAAAACG 
CGCGCCAACG TTGACAAGGT ATTTTTTGAT TTAATGAGGG AAATACGAGC CAGAAAGATG 
GAAGACAGCA AAGAAAAAAA TGGAAAAAAG AAGAGGAAAA GTTTAGCCAA GAGAATCAGA 
GAAAGATGCT GCATTTTATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rala ( XM_017600665.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017456154.1 Rattus norvegicus RALA Ras like proto-oncogene A (Rala), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa37913
Clone ID Related Accession (Same CDS sequence)	XM_006253993.3 , XM_017600665.1 , XM_017600664.1
Accession Version	XM_017600665.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 621bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	ras-related protein Ral-A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005116.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGCAA ACAAGCCCAA GGGTCAGAAT TCTTTGGCCT TACACAAAGT CATCATGGTG 
GGCAGTGGTG GTGTGGGCAA GTCTGCTCTG ACTCTGCAGT TCATGTATGA TGAGTTTGTA 
GAAGACTATG AACCTACCAA AGCAGACAGC TACAGGAAGA AGGTAGTGCT GGATGGGGAG 
GAAGTGCAGA TCGACATCTT AGATACAGCA GGGCAGGAAG ACTACGCTGC AATTAGAGAC 
AACTACTTCC GAAGTGGGGA GGGATTCCTC TGTGTCTTCT CTATCACAGA GATGGAGTCC 
TTTGCAGCTA CAGCGGACTT CAGGGAACAG ATTTTAAGAG TAAAAGAAGA TGAGAATGTC 
CCATTTCTCC TGGTTGGTAA CAAATCAGAT TTAGAAGATA AAAGGCAGGT TTCTGTAGAA 
GAGGCAAAAA ACAGAGCTGA CCAGTGGAAC GTTAACTATG TGGAGACGTC TGCTAAAACG 
CGCGCCAACG TTGACAAGGT ATTTTTTGAT TTAATGAGGG AAATACGAGC CAGAAAGATG 
GAAGACAGCA AAGAAAAAAA TGGAAAAAAG AAGAGGAAAA GTTTAGCCAA GAGAATCAGA 
GAAAGATGCT GCATTTTATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017456154.1
CDS	317..937
Translation	MAANKPKGQNSLALHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILRVKEDENVPFLLVGNKSDLEDKRQVSVEEAKNRADQWNVNYVETSAKTRANVDKVFFDLMREIRARKMEDSKEKNGKKKRKSLAKRIRERCCIL

Target ORF information:

RefSeq Version	XM_017600665.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus RALA Ras like proto-oncogene A (Rala), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017600665.1

ORF Insert Sequence:

ATGGCTGCAA ACAAGCCCAA GGGTCAGAAT TCTTTGGCCT TACACAAAGT CATCATGGTG 
GGCAGTGGTG GTGTGGGCAA GTCTGCTCTG ACTCTGCAGT TCATGTATGA TGAGTTTGTA 
GAAGACTATG AACCTACCAA AGCAGACAGC TACAGGAAGA AGGTAGTGCT GGATGGGGAG 
GAAGTGCAGA TCGACATCTT AGATACAGCA GGGCAGGAAG ACTACGCTGC AATTAGAGAC 
AACTACTTCC GAAGTGGGGA GGGATTCCTC TGTGTCTTCT CTATCACAGA GATGGAGTCC 
TTTGCAGCTA CAGCGGACTT CAGGGAACAG ATTTTAAGAG TAAAAGAAGA TGAGAATGTC 
CCATTTCTCC TGGTTGGTAA CAAATCAGAT TTAGAAGATA AAAGGCAGGT TTCTGTAGAA 
GAGGCAAAAA ACAGAGCTGA CCAGTGGAAC GTTAACTATG TGGAGACGTC TGCTAAAACG 
CGCGCCAACG TTGACAAGGT ATTTTTTGAT TTAATGAGGG AAATACGAGC CAGAAAGATG 
GAAGACAGCA AAGAAAAAAA TGGAAAAAAG AAGAGGAAAA GTTTAGCCAA GAGAATCAGA 
GAAAGATGCT GCATTTTATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rala ( XM_017600664.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017456153.1 Rattus norvegicus RALA Ras like proto-oncogene A (Rala), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa37913
Clone ID Related Accession (Same CDS sequence)	XM_006253993.3 , XM_017600665.1 , XM_017600664.1
Accession Version	XM_017600664.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 621bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	ras-related protein Ral-A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005116.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGCAA ACAAGCCCAA GGGTCAGAAT TCTTTGGCCT TACACAAAGT CATCATGGTG 
GGCAGTGGTG GTGTGGGCAA GTCTGCTCTG ACTCTGCAGT TCATGTATGA TGAGTTTGTA 
GAAGACTATG AACCTACCAA AGCAGACAGC TACAGGAAGA AGGTAGTGCT GGATGGGGAG 
GAAGTGCAGA TCGACATCTT AGATACAGCA GGGCAGGAAG ACTACGCTGC AATTAGAGAC 
AACTACTTCC GAAGTGGGGA GGGATTCCTC TGTGTCTTCT CTATCACAGA GATGGAGTCC 
TTTGCAGCTA CAGCGGACTT CAGGGAACAG ATTTTAAGAG TAAAAGAAGA TGAGAATGTC 
CCATTTCTCC TGGTTGGTAA CAAATCAGAT TTAGAAGATA AAAGGCAGGT TTCTGTAGAA 
GAGGCAAAAA ACAGAGCTGA CCAGTGGAAC GTTAACTATG TGGAGACGTC TGCTAAAACG 
CGCGCCAACG TTGACAAGGT ATTTTTTGAT TTAATGAGGG AAATACGAGC CAGAAAGATG 
GAAGACAGCA AAGAAAAAAA TGGAAAAAAG AAGAGGAAAA GTTTAGCCAA GAGAATCAGA 
GAAAGATGCT GCATTTTATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017456153.1
CDS	905..1525
Translation	MAANKPKGQNSLALHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILRVKEDENVPFLLVGNKSDLEDKRQVSVEEAKNRADQWNVNYVETSAKTRANVDKVFFDLMREIRARKMEDSKEKNGKKKRKSLAKRIRERCCIL

Target ORF information:

RefSeq Version	XM_017600664.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus RALA Ras like proto-oncogene A (Rala), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017600664.1

ORF Insert Sequence:

ATGGCTGCAA ACAAGCCCAA GGGTCAGAAT TCTTTGGCCT TACACAAAGT CATCATGGTG 
GGCAGTGGTG GTGTGGGCAA GTCTGCTCTG ACTCTGCAGT TCATGTATGA TGAGTTTGTA 
GAAGACTATG AACCTACCAA AGCAGACAGC TACAGGAAGA AGGTAGTGCT GGATGGGGAG 
GAAGTGCAGA TCGACATCTT AGATACAGCA GGGCAGGAAG ACTACGCTGC AATTAGAGAC 
AACTACTTCC GAAGTGGGGA GGGATTCCTC TGTGTCTTCT CTATCACAGA GATGGAGTCC 
TTTGCAGCTA CAGCGGACTT CAGGGAACAG ATTTTAAGAG TAAAAGAAGA TGAGAATGTC 
CCATTTCTCC TGGTTGGTAA CAAATCAGAT TTAGAAGATA AAAGGCAGGT TTCTGTAGAA 
GAGGCAAAAA ACAGAGCTGA CCAGTGGAAC GTTAACTATG TGGAGACGTC TGCTAAAACG 
CGCGCCAACG TTGACAAGGT ATTTTTTGAT TTAATGAGGG AAATACGAGC CAGAAAGATG 
GAAGACAGCA AAGAAAAAAA TGGAAAAAAG AAGAGGAAAA GTTTAGCCAA GAGAATCAGA 
GAAAGATGCT GCATTTTATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Dysregulation of KRAS signaling in pancreatic cancer is not associated with
Oncology letters14(5)5980-5988(2017 Nov)
Lemstrova R,Brynychova V,Hughes DJ,Hlavac V,Dvorak P,Doherty JE,Murray HA,Crockard M,Oliverius M,Hlavsa J,Honsova E,Mazanec J,Kala Z,Lovecek M,Havlik R,Ehrmann J,Strouhal O,Soucek P,Melichar B,Mohelnikova-Duchonova B

Longest neurite-specific activation of Rap1B in hippocampal neurons contributes to polarity formation through RalA and Nore1A in addition to PI3-kinase.
Genes to cells : devoted to molecular & cellular mechanisms18(11)1020-31(2013 Nov)
Nakamura T,Yasuda S,Nagai H,Koinuma S,Morishita S,Goto A,Kinashi T,Wada N

The deubiquitylase USP33 discriminates between RALB functions in autophagy and innate immune response.
Nature cell biology15(10)1220-30(2013 Oct)
Simicek M,Lievens S,Laga M,Guzenko D,Aushev VN,Kalev P,Baietti MF,Strelkov SV,Gevaert K,Tavernier J,Sablina AA

RalA GTPase tethers insulin granules to L- and R-type calcium channels through binding ?2 ?-1 subunit.
Traffic (Copenhagen, Denmark)14(4)428-39(2013 Apr)
Xie L,Kang Y,Liang T,Dolai S,Xie H,Parsaud L,Lopez JA,He Y,Chidambaram S,Lam PP,James DE,Sugita S,Gaisano HY

Genetic deletion of RALA and RALB small GTPases reveals redundant functions in development and tumorigenesis.
Current biology : CB22(21)2063-8(2012 Nov)
Peschard P,McCarthy A,Leblanc-Dominguez V,Yeo M,Guichard S,Stamp G,Marshall CJ

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

Rala cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報