Psen2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Psen2
Entrez Gene ID	81751
Full Name	presenilin 2
General protein information	Preferred Names presenilin 2 Names presenilin-2 PS-2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 13 Map Location: 13q26
Summary	mutations in human homolog responsible for chromosome 1-linked familial Alzheimer's disease; expression increased during brain development but decreased in the adult [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006250405.3	XP_006250467.1	presenilin-2 isoform X1
XM_008769877.2	XP_008768099.1	presenilin-2 isoform X1
XM_006250410.3	XP_006250472.1	presenilin-2 isoform X2
XM_006250407.3	XP_006250469.1	presenilin-2 isoform X1
XM_006250408.3	XP_006250470.1	presenilin-2 isoform X1
NM_031087.2	NP_112349.2	presenilin-2
XM_017598939.1	XP_017454428.1	presenilin-2 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	PSEN2	NP_000438.2
	PSEN2	XP_002801954.1
Canis lupus familiaris (dog)	PSEN2	XP_005622685.1
Danio rerio (zebrafish)	psen2	NP_571589.2
Xenopus tropicalis (tropical clawed frog)	psen2	NP_001017181.1
Bos taurus (cattle)	PSEN2	NP_776865.2
Rattus norvegicus (Norway rat)	Psen2	NP_112349.2
Drosophila melanogaster (fruit fly)	Psn	NP_001137988.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002957	XP_311942.4
Gallus gallus (chicken)	PSEN2	NP_989633.1
Oryza sativa (rice)	Os01g0276400	NP_001042728.2
Pan troglodytes (chimpanzee)	PSEN2	XP_003949755.1
Mus musculus (house mouse)	Psen2	NP_001122077.1

Gene Ontology
Bibliography

Related articles in PubMed

A Presenilin/Notch1 pathway regulated by miR-375, miR-30a, and miR-34a mediates glucotoxicity induced-pancreatic beta cell apoptosis.
Li Y, Zhang T, Zhou Y, Sun Y, Cao Y, Chang X, Zhu Y, Han X
Scientific reports636136(2016 Nov)

Alzheimer-associated presenilin 2 gene is dysregulated in rat medial temporal lobe cortex after complete brain ischemia due to cardiac arrest.
Pluta R, Kocki J, U?amek-Kozio? M, Bogucka-Kocka A, Gil-Kulik P, Januszewski S, Jab?o?ski M, Petniak A, Brzozowska J, Bogucki J, Furmaga-Jab?o?ska W, Czuczwar SJ
Pharmacological reports : PR68(1)155-61(2016 Feb)

Partial loss of presenilin impairs age-dependent neuronal survival in the cerebral cortex.
Watanabe H, Iqbal M, Zheng J, Wines-Samuelson M, Shen J
The Journal of neuroscience : the official journal of the Society for Neuroscience34(48)15912-22(2014 Nov)

A role for the primary cilium in Notch signaling and epidermal differentiation during skin development.
Ezratty EJ, Stokes N, Chai S, Shah AS, Williams SE, Fuchs E
Cell145(7)1129-41(2011 Jun)

Presenilin 2 modulates endoplasmic reticulum (ER)-mitochondria interactions and Ca2+ cross-talk.
Zampese E, Fasolato C, Kipanyula MJ, Bortolozzi M, Pozzan T, Pizzo P
Proceedings of the National Academy of Sciences of the United States of America108(7)2777-82(2011 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Significant dysregulation of presenilin 2 gene was found in neuronal cells following brain ischemia due to cardiac arrest.
Title: Alzheimer-associated presenilin 2 gene is dysregulated in rat medial temporal lobe cortex after complete brain ischemia due to cardiac arrest.

Ablation of presenilins results in deficiency of CD8 cells in the periphery and a dramatic change in the physiology of thymocytes.
Title: Effect of presenilins in the apoptosis of thymocytes and homeostasis of CD8+ T cells.

These findings indicated that mutant presenilin 2 clearly increases oxidative stress and p53 expression, which could be implicated in promoting mutant presenilin 2-induced neurodegeneration in Alzheimer's disease.
Title: Mutant presenilin 2 increased oxidative stress and p53 expression in neuronal cells.

PS2-LP-mediated alteration of intracellular Ca(2+) homeostasis may be linked to the acceleration of apoptosis
Title: The presenilin-2 loop peptide perturbs intracellular Ca2+ homeostasis and accelerates apoptosis.

Calmyrin binds specifically endogenous preseninin-2 (PS2) and not PS1.
Title: Ca2+-independent binding and cellular expression profiles question a significant role of calmyrin in transduction of Ca2+-signals to Alzheimer's disease-related presenilin 2 in forebrain.

The following Psen2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Psen2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa07558	NM_031087.2 Latest version!	Rattus norvegicus presenilin 2 (Psen2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa07558	XM_006250407.3 Latest version!	Rattus norvegicus presenilin 2 (Psen2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa07558	XM_017598939.1 Latest version!	Rattus norvegicus presenilin 2 (Psen2), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa07558	XM_006250408.3 Latest version!	Rattus norvegicus presenilin 2 (Psen2), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa07558	XM_006250405.3 Latest version!	Rattus norvegicus presenilin 2 (Psen2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa07558	XM_008769877.2 Latest version!	Rattus norvegicus presenilin 2 (Psen2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa35702	XM_006250410.3 Latest version!	Rattus norvegicus presenilin 2 (Psen2), transcript variant X6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Psen2 ( NM_031087.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_112349.2 Rattus norvegicus presenilin 2 (Psen2), mRNA.

Price & Availability↑

CloneID	ORa07558
Clone ID Related Accession (Same CDS sequence)	XM_006250405.3 , XM_008769877.2 , XM_006250407.3 , XM_006250408.3 , NM_031087.2 , XM_017598939.1
Accession Version	NM_031087.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1347bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Rattus norvegicus(Norway rat)
Product	presenilin-2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC078805.1. On Jun 10, 2007 this sequence version replaced NM_031087.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC078805.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGCTCACAT TCATGGCCTC TGATAGCGAG GAAGAGGTGT GCGATGAGCG GACGTCCTTG 
ATGTCAGCCG AGAGCCCTAC ATCACGTTCC TGCCAGGACA GCAGGCCAGG CCCAGAGGAT 
GGAGAGAACA CTGCCCAGTG GAGGAGCCAG GAGAACGAGG ACGACTGTGA GGAGGACCCG 
GACCACTATG CCTGCAGTGG GGTTCCTGGG CGACCATCGG GCCTGGAGGA GGAGCTGACC 
CTCAAGTATG GGGCGAAGCA CGTGATCATG CTGTTCGTGC CTGTCACGCT GTGCATGATT 
GTGGTGGTGG CCACCATCAA GTCCGTGCGT TTCTACACGG AGAAGAACGG GCAGCTCATC 
TACACGCCCT TCACCGAGGA CACACCCTCT GTGGGCCAGC GGCTCCTCAA CTCCGTGCTG 
AACACTCTGA TCATGATCAG CGTCATTGTG GTCATGACTA TCTTCCTAGT GGTACTCTAC 
AAATATCGCT GTTACAAGTT CATCCATGGC TGGCTGATCA TGTCCTCCCT GATGCTCCTC 
TTCTTGTTCA CCTACATCTA CCTCGGGGAA GTGTTCAAGA CCTACAATGT GGCCATGGAC 
TACCCCACAC TGTTCCTGGC TGTCTGGAAC TTCGGGGCAG TGGGCATGGT GTGCATCCAC 
TGGAAGGGTC CCCTGGTGCT CCAGCAGGCT TACCTCATTG TGATCAGCGC ACTCATGGCC 
CTGGTGTTCA TCAAGTACCT GCCGGAGTGG TCCGCTTGGG TCATCTTGGG CGCCATCTCT 
GTGTACGATC TCGTGGCTGT GCTGTGCCCC AAAGGGCCAC TGAGGATGCT GGTGGAAACT 
GCCCAGGAAA GAAACGAGCC CATATTTCCT GCCCTCATAT ACTCATCTGC CATGGTGTGG 
ACGGTAGGCA TGGCGAAGCT GGACCCCTCC TCTCAGGGAG CACTGCAGCT CCCTTACGAT 
CCAGAGATGG AAGAAGACTC CTATGACAGT TTTGGGGAAC CCTCATACCC TGAAGCCTTC 
GAAGCTCCCC AGCCTGGCTA CCCAGGGGAA GAGCCGGAGG AGGAGGAGGA AAGGGGTGTA 
AAGCTTGGTC TGGGAGACTT CATCTTCTAC AGCGTTCTGG TGGGCAAGGC AGCAGCCACA 
GGCAACGGAG ACTGGAGCAC GACGCTGGCC TGCTTTATCG CCATCCTCAT TGGCTTGTGT 
CTCACCCTCC TGCTGCTCGC CGTGTTCAAG AAGGCCCTGC CCGCCCTCCC CATCTCCATC 
ACCTTCGGGC TCATCTTTTA CTTCTCCACA GACAACCTGG TGCGTCCTTT CATGGACACG 
TTGGCCTCCC ACCAGCTCTA CATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_112349.2
CDS	98..1444
Translation	MLTFMASDSEEEVCDERTSLMSAESPTSRSCQDSRPGPEDGENTAQWRSQENEDDCEEDPDHYACSGVPGRPSGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLLFLFTYIYLGEVFKTYNVAMDYPTLFLAVWNFGAVGMVCIHWKGPLVLQQAYLIVISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTVGMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEAFEAPQPGYPGEEPEEEEERGVKLGLGDFIFYSVLVGKAAATGNGDWSTTLACFIAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI

Target ORF information:

RefSeq Version	NM_031087.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus presenilin 2 (Psen2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031087.2

ORF Insert Sequence:

ATGCTCACAT TCATGGCCTC TGATAGCGAG GAAGAGGTGT GCGATGAGCG GACGTCCTTG 
ATGTCAGCCG AGAGCCCTAC ATCACGTTCC TGCCAGGACA GCAGGCCAGG CCCAGAGGAT 
GGAGAGAACA CTGCCCAGTG GAGGAGCCAG GAGAACGAGG ACGACTGTGA GGAGGACCCG 
GACCACTATG CCTGCAGTGG GGTTCCTGGG CGACCATCGG GCCTGGAGGA GGAGCTGACC 
CTCAAGTATG GGGCGAAGCA CGTGATCATG CTGTTCGTGC CTGTCACGCT GTGCATGATT 
GTGGTGGTGG CCACCATCAA GTCCGTGCGT TTCTACACGG AGAAGAACGG GCAGCTCATC 
TACACGCCCT TCACCGAGGA CACACCCTCT GTGGGCCAGC GGCTCCTCAA CTCCGTGCTG 
AACACTCTGA TCATGATCAG CGTCATTGTG GTCATGACTA TCTTCCTAGT GGTACTCTAC 
AAATATCGCT GTTACAAGTT CATCCATGGC TGGCTGATCA TGTCCTCCCT GATGCTCCTC 
TTCTTGTTCA CCTACATCTA CCTCGGGGAA GTGTTCAAGA CCTACAATGT GGCCATGGAC 
TACCCCACAC TGTTCCTGGC TGTCTGGAAC TTCGGGGCAG TGGGCATGGT GTGCATCCAC 
TGGAAGGGTC CCCTGGTGCT CCAGCAGGCT TACCTCATTG TGATCAGCGC ACTCATGGCC 
CTGGTGTTCA TCAAGTACCT GCCGGAGTGG TCCGCTTGGG TCATCTTGGG CGCCATCTCT 
GTGTACGATC TCGTGGCTGT GCTGTGCCCC AAAGGGCCAC TGAGGATGCT GGTGGAAACT 
GCCCAGGAAA GAAACGAGCC CATATTTCCT GCCCTCATAT ACTCATCTGC CATGGTGTGG 
ACGGTAGGCA TGGCGAAGCT GGACCCCTCC TCTCAGGGAG CACTGCAGCT CCCTTACGAT 
CCAGAGATGG AAGAAGACTC CTATGACAGT TTTGGGGAAC CCTCATACCC TGAAGCCTTC 
GAAGCTCCCC AGCCTGGCTA CCCAGGGGAA GAGCCGGAGG AGGAGGAGGA AAGGGGTGTA 
AAGCTTGGTC TGGGAGACTT CATCTTCTAC AGCGTTCTGG TGGGCAAGGC AGCAGCCACA 
GGCAACGGAG ACTGGAGCAC GACGCTGGCC TGCTTTATCG CCATCCTCAT TGGCTTGTGT 
CTCACCCTCC TGCTGCTCGC CGTGTTCAAG AAGGCCCTGC CCGCCCTCCC CATCTCCATC 
ACCTTCGGGC TCATCTTTTA CTTCTCCACA GACAACCTGG TGCGTCCTTT CATGGACACG 
TTGGCCTCCC ACCAGCTCTA CATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Psen2 ( XM_006250405.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006250467.1 Rattus norvegicus presenilin 2 (Psen2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa07558
Clone ID Related Accession (Same CDS sequence)	XM_006250405.3 , XM_008769877.2 , XM_006250407.3 , XM_006250408.3 , NM_031087.2 , XM_017598939.1
Accession Version	XM_006250405.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1347bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	presenilin-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005112.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006250405.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTCACAT TCATGGCCTC TGATAGCGAG GAAGAGGTGT GCGATGAGCG GACGTCCTTG 
ATGTCAGCCG AGAGCCCTAC ATCACGTTCC TGCCAGGACA GCAGGCCAGG CCCAGAGGAT 
GGAGAGAACA CTGCCCAGTG GAGGAGCCAG GAGAACGAGG ACGACTGTGA GGAGGACCCG 
GACCACTATG CCTGCAGTGG GGTTCCTGGG CGACCATCGG GCCTGGAGGA GGAGCTGACC 
CTCAAGTATG GGGCGAAGCA CGTGATCATG CTGTTCGTGC CTGTCACGCT GTGCATGATT 
GTGGTGGTGG CCACCATCAA GTCCGTGCGT TTCTACACGG AGAAGAACGG GCAGCTCATC 
TACACGCCCT TCACCGAGGA CACACCCTCT GTGGGCCAGC GGCTCCTCAA CTCCGTGCTG 
AACACTCTGA TCATGATCAG CGTCATTGTG GTCATGACTA TCTTCCTAGT GGTACTCTAC 
AAATATCGCT GTTACAAGTT CATCCATGGC TGGCTGATCA TGTCCTCCCT GATGCTCCTC 
TTCTTGTTCA CCTACATCTA CCTCGGGGAA GTGTTCAAGA CCTACAATGT GGCCATGGAC 
TACCCCACAC TGTTCCTGGC TGTCTGGAAC TTCGGGGCAG TGGGCATGGT GTGCATCCAC 
TGGAAGGGTC CCCTGGTGCT CCAGCAGGCT TACCTCATTG TGATCAGCGC ACTCATGGCC 
CTGGTGTTCA TCAAGTACCT GCCGGAGTGG TCCGCTTGGG TCATCTTGGG CGCCATCTCT 
GTGTACGATC TCGTGGCTGT GCTGTGCCCC AAAGGGCCAC TGAGGATGCT GGTGGAAACT 
GCCCAGGAAA GAAACGAGCC CATATTTCCT GCCCTCATAT ACTCATCTGC CATGGTGTGG 
ACGGTAGGCA TGGCGAAGCT GGACCCCTCC TCTCAGGGAG CACTGCAGCT CCCTTACGAT 
CCAGAGATGG AAGAAGACTC CTATGACAGT TTTGGGGAAC CCTCATACCC TGAAGCCTTC 
GAAGCTCCCC AGCCTGGCTA CCCAGGGGAA GAGCCGGAGG AGGAGGAGGA AAGGGGTGTA 
AAGCTTGGTC TGGGAGACTT CATCTTCTAC AGCGTTCTGG TGGGCAAGGC AGCAGCCACA 
GGCAACGGAG ACTGGAGCAC GACGCTGGCC TGCTTTATCG CCATCCTCAT TGGCTTGTGT 
CTCACCCTCC TGCTGCTCGC CGTGTTCAAG AAGGCCCTGC CCGCCCTCCC CATCTCCATC 
ACCTTCGGGC TCATCTTTTA CTTCTCCACA GACAACCTGG TGCGTCCTTT CATGGACACG 
TTGGCCTCCC ACCAGCTCTA CATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006250467.1
CDS	283..1629
Translation	MLTFMASDSEEEVCDERTSLMSAESPTSRSCQDSRPGPEDGENTAQWRSQENEDDCEEDPDHYACSGVPGRPSGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLLFLFTYIYLGEVFKTYNVAMDYPTLFLAVWNFGAVGMVCIHWKGPLVLQQAYLIVISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTVGMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEAFEAPQPGYPGEEPEEEEERGVKLGLGDFIFYSVLVGKAAATGNGDWSTTLACFIAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI

Target ORF information:

RefSeq Version	XM_006250405.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus presenilin 2 (Psen2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006250405.3

ORF Insert Sequence:

ATGCTCACAT TCATGGCCTC TGATAGCGAG GAAGAGGTGT GCGATGAGCG GACGTCCTTG 
ATGTCAGCCG AGAGCCCTAC ATCACGTTCC TGCCAGGACA GCAGGCCAGG CCCAGAGGAT 
GGAGAGAACA CTGCCCAGTG GAGGAGCCAG GAGAACGAGG ACGACTGTGA GGAGGACCCG 
GACCACTATG CCTGCAGTGG GGTTCCTGGG CGACCATCGG GCCTGGAGGA GGAGCTGACC 
CTCAAGTATG GGGCGAAGCA CGTGATCATG CTGTTCGTGC CTGTCACGCT GTGCATGATT 
GTGGTGGTGG CCACCATCAA GTCCGTGCGT TTCTACACGG AGAAGAACGG GCAGCTCATC 
TACACGCCCT TCACCGAGGA CACACCCTCT GTGGGCCAGC GGCTCCTCAA CTCCGTGCTG 
AACACTCTGA TCATGATCAG CGTCATTGTG GTCATGACTA TCTTCCTAGT GGTACTCTAC 
AAATATCGCT GTTACAAGTT CATCCATGGC TGGCTGATCA TGTCCTCCCT GATGCTCCTC 
TTCTTGTTCA CCTACATCTA CCTCGGGGAA GTGTTCAAGA CCTACAATGT GGCCATGGAC 
TACCCCACAC TGTTCCTGGC TGTCTGGAAC TTCGGGGCAG TGGGCATGGT GTGCATCCAC 
TGGAAGGGTC CCCTGGTGCT CCAGCAGGCT TACCTCATTG TGATCAGCGC ACTCATGGCC 
CTGGTGTTCA TCAAGTACCT GCCGGAGTGG TCCGCTTGGG TCATCTTGGG CGCCATCTCT 
GTGTACGATC TCGTGGCTGT GCTGTGCCCC AAAGGGCCAC TGAGGATGCT GGTGGAAACT 
GCCCAGGAAA GAAACGAGCC CATATTTCCT GCCCTCATAT ACTCATCTGC CATGGTGTGG 
ACGGTAGGCA TGGCGAAGCT GGACCCCTCC TCTCAGGGAG CACTGCAGCT CCCTTACGAT 
CCAGAGATGG AAGAAGACTC CTATGACAGT TTTGGGGAAC CCTCATACCC TGAAGCCTTC 
GAAGCTCCCC AGCCTGGCTA CCCAGGGGAA GAGCCGGAGG AGGAGGAGGA AAGGGGTGTA 
AAGCTTGGTC TGGGAGACTT CATCTTCTAC AGCGTTCTGG TGGGCAAGGC AGCAGCCACA 
GGCAACGGAG ACTGGAGCAC GACGCTGGCC TGCTTTATCG CCATCCTCAT TGGCTTGTGT 
CTCACCCTCC TGCTGCTCGC CGTGTTCAAG AAGGCCCTGC CCGCCCTCCC CATCTCCATC 
ACCTTCGGGC TCATCTTTTA CTTCTCCACA GACAACCTGG TGCGTCCTTT CATGGACACG 
TTGGCCTCCC ACCAGCTCTA CATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Psen2 ( XM_008769877.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008768099.1 Rattus norvegicus presenilin 2 (Psen2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa07558
Clone ID Related Accession (Same CDS sequence)	XM_006250405.3 , XM_008769877.2 , XM_006250407.3 , XM_006250408.3 , NM_031087.2 , XM_017598939.1
Accession Version	XM_008769877.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1347bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	presenilin-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005112.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008769877.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTCACAT TCATGGCCTC TGATAGCGAG GAAGAGGTGT GCGATGAGCG GACGTCCTTG 
ATGTCAGCCG AGAGCCCTAC ATCACGTTCC TGCCAGGACA GCAGGCCAGG CCCAGAGGAT 
GGAGAGAACA CTGCCCAGTG GAGGAGCCAG GAGAACGAGG ACGACTGTGA GGAGGACCCG 
GACCACTATG CCTGCAGTGG GGTTCCTGGG CGACCATCGG GCCTGGAGGA GGAGCTGACC 
CTCAAGTATG GGGCGAAGCA CGTGATCATG CTGTTCGTGC CTGTCACGCT GTGCATGATT 
GTGGTGGTGG CCACCATCAA GTCCGTGCGT TTCTACACGG AGAAGAACGG GCAGCTCATC 
TACACGCCCT TCACCGAGGA CACACCCTCT GTGGGCCAGC GGCTCCTCAA CTCCGTGCTG 
AACACTCTGA TCATGATCAG CGTCATTGTG GTCATGACTA TCTTCCTAGT GGTACTCTAC 
AAATATCGCT GTTACAAGTT CATCCATGGC TGGCTGATCA TGTCCTCCCT GATGCTCCTC 
TTCTTGTTCA CCTACATCTA CCTCGGGGAA GTGTTCAAGA CCTACAATGT GGCCATGGAC 
TACCCCACAC TGTTCCTGGC TGTCTGGAAC TTCGGGGCAG TGGGCATGGT GTGCATCCAC 
TGGAAGGGTC CCCTGGTGCT CCAGCAGGCT TACCTCATTG TGATCAGCGC ACTCATGGCC 
CTGGTGTTCA TCAAGTACCT GCCGGAGTGG TCCGCTTGGG TCATCTTGGG CGCCATCTCT 
GTGTACGATC TCGTGGCTGT GCTGTGCCCC AAAGGGCCAC TGAGGATGCT GGTGGAAACT 
GCCCAGGAAA GAAACGAGCC CATATTTCCT GCCCTCATAT ACTCATCTGC CATGGTGTGG 
ACGGTAGGCA TGGCGAAGCT GGACCCCTCC TCTCAGGGAG CACTGCAGCT CCCTTACGAT 
CCAGAGATGG AAGAAGACTC CTATGACAGT TTTGGGGAAC CCTCATACCC TGAAGCCTTC 
GAAGCTCCCC AGCCTGGCTA CCCAGGGGAA GAGCCGGAGG AGGAGGAGGA AAGGGGTGTA 
AAGCTTGGTC TGGGAGACTT CATCTTCTAC AGCGTTCTGG TGGGCAAGGC AGCAGCCACA 
GGCAACGGAG ACTGGAGCAC GACGCTGGCC TGCTTTATCG CCATCCTCAT TGGCTTGTGT 
CTCACCCTCC TGCTGCTCGC CGTGTTCAAG AAGGCCCTGC CCGCCCTCCC CATCTCCATC 
ACCTTCGGGC TCATCTTTTA CTTCTCCACA GACAACCTGG TGCGTCCTTT CATGGACACG 
TTGGCCTCCC ACCAGCTCTA CATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008768099.1
CDS	384..1730
Translation	MLTFMASDSEEEVCDERTSLMSAESPTSRSCQDSRPGPEDGENTAQWRSQENEDDCEEDPDHYACSGVPGRPSGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLLFLFTYIYLGEVFKTYNVAMDYPTLFLAVWNFGAVGMVCIHWKGPLVLQQAYLIVISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTVGMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEAFEAPQPGYPGEEPEEEEERGVKLGLGDFIFYSVLVGKAAATGNGDWSTTLACFIAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI

Target ORF information:

RefSeq Version	XM_008769877.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus presenilin 2 (Psen2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008769877.2

ORF Insert Sequence:

ATGCTCACAT TCATGGCCTC TGATAGCGAG GAAGAGGTGT GCGATGAGCG GACGTCCTTG 
ATGTCAGCCG AGAGCCCTAC ATCACGTTCC TGCCAGGACA GCAGGCCAGG CCCAGAGGAT 
GGAGAGAACA CTGCCCAGTG GAGGAGCCAG GAGAACGAGG ACGACTGTGA GGAGGACCCG 
GACCACTATG CCTGCAGTGG GGTTCCTGGG CGACCATCGG GCCTGGAGGA GGAGCTGACC 
CTCAAGTATG GGGCGAAGCA CGTGATCATG CTGTTCGTGC CTGTCACGCT GTGCATGATT 
GTGGTGGTGG CCACCATCAA GTCCGTGCGT TTCTACACGG AGAAGAACGG GCAGCTCATC 
TACACGCCCT TCACCGAGGA CACACCCTCT GTGGGCCAGC GGCTCCTCAA CTCCGTGCTG 
AACACTCTGA TCATGATCAG CGTCATTGTG GTCATGACTA TCTTCCTAGT GGTACTCTAC 
AAATATCGCT GTTACAAGTT CATCCATGGC TGGCTGATCA TGTCCTCCCT GATGCTCCTC 
TTCTTGTTCA CCTACATCTA CCTCGGGGAA GTGTTCAAGA CCTACAATGT GGCCATGGAC 
TACCCCACAC TGTTCCTGGC TGTCTGGAAC TTCGGGGCAG TGGGCATGGT GTGCATCCAC 
TGGAAGGGTC CCCTGGTGCT CCAGCAGGCT TACCTCATTG TGATCAGCGC ACTCATGGCC 
CTGGTGTTCA TCAAGTACCT GCCGGAGTGG TCCGCTTGGG TCATCTTGGG CGCCATCTCT 
GTGTACGATC TCGTGGCTGT GCTGTGCCCC AAAGGGCCAC TGAGGATGCT GGTGGAAACT 
GCCCAGGAAA GAAACGAGCC CATATTTCCT GCCCTCATAT ACTCATCTGC CATGGTGTGG 
ACGGTAGGCA TGGCGAAGCT GGACCCCTCC TCTCAGGGAG CACTGCAGCT CCCTTACGAT 
CCAGAGATGG AAGAAGACTC CTATGACAGT TTTGGGGAAC CCTCATACCC TGAAGCCTTC 
GAAGCTCCCC AGCCTGGCTA CCCAGGGGAA GAGCCGGAGG AGGAGGAGGA AAGGGGTGTA 
AAGCTTGGTC TGGGAGACTT CATCTTCTAC AGCGTTCTGG TGGGCAAGGC AGCAGCCACA 
GGCAACGGAG ACTGGAGCAC GACGCTGGCC TGCTTTATCG CCATCCTCAT TGGCTTGTGT 
CTCACCCTCC TGCTGCTCGC CGTGTTCAAG AAGGCCCTGC CCGCCCTCCC CATCTCCATC 
ACCTTCGGGC TCATCTTTTA CTTCTCCACA GACAACCTGG TGCGTCCTTT CATGGACACG 
TTGGCCTCCC ACCAGCTCTA CATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Psen2 ( XM_006250407.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006250469.1 Rattus norvegicus presenilin 2 (Psen2), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa07558
Clone ID Related Accession (Same CDS sequence)	XM_006250405.3 , XM_008769877.2 , XM_006250407.3 , XM_006250408.3 , NM_031087.2 , XM_017598939.1
Accession Version	XM_006250407.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1347bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	presenilin-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005112.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006250407.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTCACAT TCATGGCCTC TGATAGCGAG GAAGAGGTGT GCGATGAGCG GACGTCCTTG 
ATGTCAGCCG AGAGCCCTAC ATCACGTTCC TGCCAGGACA GCAGGCCAGG CCCAGAGGAT 
GGAGAGAACA CTGCCCAGTG GAGGAGCCAG GAGAACGAGG ACGACTGTGA GGAGGACCCG 
GACCACTATG CCTGCAGTGG GGTTCCTGGG CGACCATCGG GCCTGGAGGA GGAGCTGACC 
CTCAAGTATG GGGCGAAGCA CGTGATCATG CTGTTCGTGC CTGTCACGCT GTGCATGATT 
GTGGTGGTGG CCACCATCAA GTCCGTGCGT TTCTACACGG AGAAGAACGG GCAGCTCATC 
TACACGCCCT TCACCGAGGA CACACCCTCT GTGGGCCAGC GGCTCCTCAA CTCCGTGCTG 
AACACTCTGA TCATGATCAG CGTCATTGTG GTCATGACTA TCTTCCTAGT GGTACTCTAC 
AAATATCGCT GTTACAAGTT CATCCATGGC TGGCTGATCA TGTCCTCCCT GATGCTCCTC 
TTCTTGTTCA CCTACATCTA CCTCGGGGAA GTGTTCAAGA CCTACAATGT GGCCATGGAC 
TACCCCACAC TGTTCCTGGC TGTCTGGAAC TTCGGGGCAG TGGGCATGGT GTGCATCCAC 
TGGAAGGGTC CCCTGGTGCT CCAGCAGGCT TACCTCATTG TGATCAGCGC ACTCATGGCC 
CTGGTGTTCA TCAAGTACCT GCCGGAGTGG TCCGCTTGGG TCATCTTGGG CGCCATCTCT 
GTGTACGATC TCGTGGCTGT GCTGTGCCCC AAAGGGCCAC TGAGGATGCT GGTGGAAACT 
GCCCAGGAAA GAAACGAGCC CATATTTCCT GCCCTCATAT ACTCATCTGC CATGGTGTGG 
ACGGTAGGCA TGGCGAAGCT GGACCCCTCC TCTCAGGGAG CACTGCAGCT CCCTTACGAT 
CCAGAGATGG AAGAAGACTC CTATGACAGT TTTGGGGAAC CCTCATACCC TGAAGCCTTC 
GAAGCTCCCC AGCCTGGCTA CCCAGGGGAA GAGCCGGAGG AGGAGGAGGA AAGGGGTGTA 
AAGCTTGGTC TGGGAGACTT CATCTTCTAC AGCGTTCTGG TGGGCAAGGC AGCAGCCACA 
GGCAACGGAG ACTGGAGCAC GACGCTGGCC TGCTTTATCG CCATCCTCAT TGGCTTGTGT 
CTCACCCTCC TGCTGCTCGC CGTGTTCAAG AAGGCCCTGC CCGCCCTCCC CATCTCCATC 
ACCTTCGGGC TCATCTTTTA CTTCTCCACA GACAACCTGG TGCGTCCTTT CATGGACACG 
TTGGCCTCCC ACCAGCTCTA CATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006250469.1
CDS	175..1521
Translation	MLTFMASDSEEEVCDERTSLMSAESPTSRSCQDSRPGPEDGENTAQWRSQENEDDCEEDPDHYACSGVPGRPSGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLLFLFTYIYLGEVFKTYNVAMDYPTLFLAVWNFGAVGMVCIHWKGPLVLQQAYLIVISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTVGMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEAFEAPQPGYPGEEPEEEEERGVKLGLGDFIFYSVLVGKAAATGNGDWSTTLACFIAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI

Target ORF information:

RefSeq Version	XM_006250407.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus presenilin 2 (Psen2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006250407.3

ORF Insert Sequence:

ATGCTCACAT TCATGGCCTC TGATAGCGAG GAAGAGGTGT GCGATGAGCG GACGTCCTTG 
ATGTCAGCCG AGAGCCCTAC ATCACGTTCC TGCCAGGACA GCAGGCCAGG CCCAGAGGAT 
GGAGAGAACA CTGCCCAGTG GAGGAGCCAG GAGAACGAGG ACGACTGTGA GGAGGACCCG 
GACCACTATG CCTGCAGTGG GGTTCCTGGG CGACCATCGG GCCTGGAGGA GGAGCTGACC 
CTCAAGTATG GGGCGAAGCA CGTGATCATG CTGTTCGTGC CTGTCACGCT GTGCATGATT 
GTGGTGGTGG CCACCATCAA GTCCGTGCGT TTCTACACGG AGAAGAACGG GCAGCTCATC 
TACACGCCCT TCACCGAGGA CACACCCTCT GTGGGCCAGC GGCTCCTCAA CTCCGTGCTG 
AACACTCTGA TCATGATCAG CGTCATTGTG GTCATGACTA TCTTCCTAGT GGTACTCTAC 
AAATATCGCT GTTACAAGTT CATCCATGGC TGGCTGATCA TGTCCTCCCT GATGCTCCTC 
TTCTTGTTCA CCTACATCTA CCTCGGGGAA GTGTTCAAGA CCTACAATGT GGCCATGGAC 
TACCCCACAC TGTTCCTGGC TGTCTGGAAC TTCGGGGCAG TGGGCATGGT GTGCATCCAC 
TGGAAGGGTC CCCTGGTGCT CCAGCAGGCT TACCTCATTG TGATCAGCGC ACTCATGGCC 
CTGGTGTTCA TCAAGTACCT GCCGGAGTGG TCCGCTTGGG TCATCTTGGG CGCCATCTCT 
GTGTACGATC TCGTGGCTGT GCTGTGCCCC AAAGGGCCAC TGAGGATGCT GGTGGAAACT 
GCCCAGGAAA GAAACGAGCC CATATTTCCT GCCCTCATAT ACTCATCTGC CATGGTGTGG 
ACGGTAGGCA TGGCGAAGCT GGACCCCTCC TCTCAGGGAG CACTGCAGCT CCCTTACGAT 
CCAGAGATGG AAGAAGACTC CTATGACAGT TTTGGGGAAC CCTCATACCC TGAAGCCTTC 
GAAGCTCCCC AGCCTGGCTA CCCAGGGGAA GAGCCGGAGG AGGAGGAGGA AAGGGGTGTA 
AAGCTTGGTC TGGGAGACTT CATCTTCTAC AGCGTTCTGG TGGGCAAGGC AGCAGCCACA 
GGCAACGGAG ACTGGAGCAC GACGCTGGCC TGCTTTATCG CCATCCTCAT TGGCTTGTGT 
CTCACCCTCC TGCTGCTCGC CGTGTTCAAG AAGGCCCTGC CCGCCCTCCC CATCTCCATC 
ACCTTCGGGC TCATCTTTTA CTTCTCCACA GACAACCTGG TGCGTCCTTT CATGGACACG 
TTGGCCTCCC ACCAGCTCTA CATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Psen2 ( XM_006250408.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006250470.1 Rattus norvegicus presenilin 2 (Psen2), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa07558
Clone ID Related Accession (Same CDS sequence)	XM_006250405.3 , XM_008769877.2 , XM_006250407.3 , XM_006250408.3 , NM_031087.2 , XM_017598939.1
Accession Version	XM_006250408.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1347bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	presenilin-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005112.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006250408.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTCACAT TCATGGCCTC TGATAGCGAG GAAGAGGTGT GCGATGAGCG GACGTCCTTG 
ATGTCAGCCG AGAGCCCTAC ATCACGTTCC TGCCAGGACA GCAGGCCAGG CCCAGAGGAT 
GGAGAGAACA CTGCCCAGTG GAGGAGCCAG GAGAACGAGG ACGACTGTGA GGAGGACCCG 
GACCACTATG CCTGCAGTGG GGTTCCTGGG CGACCATCGG GCCTGGAGGA GGAGCTGACC 
CTCAAGTATG GGGCGAAGCA CGTGATCATG CTGTTCGTGC CTGTCACGCT GTGCATGATT 
GTGGTGGTGG CCACCATCAA GTCCGTGCGT TTCTACACGG AGAAGAACGG GCAGCTCATC 
TACACGCCCT TCACCGAGGA CACACCCTCT GTGGGCCAGC GGCTCCTCAA CTCCGTGCTG 
AACACTCTGA TCATGATCAG CGTCATTGTG GTCATGACTA TCTTCCTAGT GGTACTCTAC 
AAATATCGCT GTTACAAGTT CATCCATGGC TGGCTGATCA TGTCCTCCCT GATGCTCCTC 
TTCTTGTTCA CCTACATCTA CCTCGGGGAA GTGTTCAAGA CCTACAATGT GGCCATGGAC 
TACCCCACAC TGTTCCTGGC TGTCTGGAAC TTCGGGGCAG TGGGCATGGT GTGCATCCAC 
TGGAAGGGTC CCCTGGTGCT CCAGCAGGCT TACCTCATTG TGATCAGCGC ACTCATGGCC 
CTGGTGTTCA TCAAGTACCT GCCGGAGTGG TCCGCTTGGG TCATCTTGGG CGCCATCTCT 
GTGTACGATC TCGTGGCTGT GCTGTGCCCC AAAGGGCCAC TGAGGATGCT GGTGGAAACT 
GCCCAGGAAA GAAACGAGCC CATATTTCCT GCCCTCATAT ACTCATCTGC CATGGTGTGG 
ACGGTAGGCA TGGCGAAGCT GGACCCCTCC TCTCAGGGAG CACTGCAGCT CCCTTACGAT 
CCAGAGATGG AAGAAGACTC CTATGACAGT TTTGGGGAAC CCTCATACCC TGAAGCCTTC 
GAAGCTCCCC AGCCTGGCTA CCCAGGGGAA GAGCCGGAGG AGGAGGAGGA AAGGGGTGTA 
AAGCTTGGTC TGGGAGACTT CATCTTCTAC AGCGTTCTGG TGGGCAAGGC AGCAGCCACA 
GGCAACGGAG ACTGGAGCAC GACGCTGGCC TGCTTTATCG CCATCCTCAT TGGCTTGTGT 
CTCACCCTCC TGCTGCTCGC CGTGTTCAAG AAGGCCCTGC CCGCCCTCCC CATCTCCATC 
ACCTTCGGGC TCATCTTTTA CTTCTCCACA GACAACCTGG TGCGTCCTTT CATGGACACG 
TTGGCCTCCC ACCAGCTCTA CATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006250470.1
CDS	108..1454
Translation	MLTFMASDSEEEVCDERTSLMSAESPTSRSCQDSRPGPEDGENTAQWRSQENEDDCEEDPDHYACSGVPGRPSGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLLFLFTYIYLGEVFKTYNVAMDYPTLFLAVWNFGAVGMVCIHWKGPLVLQQAYLIVISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTVGMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEAFEAPQPGYPGEEPEEEEERGVKLGLGDFIFYSVLVGKAAATGNGDWSTTLACFIAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI

Target ORF information:

RefSeq Version	XM_006250408.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus presenilin 2 (Psen2), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006250408.3

ORF Insert Sequence:

ATGCTCACAT TCATGGCCTC TGATAGCGAG GAAGAGGTGT GCGATGAGCG GACGTCCTTG 
ATGTCAGCCG AGAGCCCTAC ATCACGTTCC TGCCAGGACA GCAGGCCAGG CCCAGAGGAT 
GGAGAGAACA CTGCCCAGTG GAGGAGCCAG GAGAACGAGG ACGACTGTGA GGAGGACCCG 
GACCACTATG CCTGCAGTGG GGTTCCTGGG CGACCATCGG GCCTGGAGGA GGAGCTGACC 
CTCAAGTATG GGGCGAAGCA CGTGATCATG CTGTTCGTGC CTGTCACGCT GTGCATGATT 
GTGGTGGTGG CCACCATCAA GTCCGTGCGT TTCTACACGG AGAAGAACGG GCAGCTCATC 
TACACGCCCT TCACCGAGGA CACACCCTCT GTGGGCCAGC GGCTCCTCAA CTCCGTGCTG 
AACACTCTGA TCATGATCAG CGTCATTGTG GTCATGACTA TCTTCCTAGT GGTACTCTAC 
AAATATCGCT GTTACAAGTT CATCCATGGC TGGCTGATCA TGTCCTCCCT GATGCTCCTC 
TTCTTGTTCA CCTACATCTA CCTCGGGGAA GTGTTCAAGA CCTACAATGT GGCCATGGAC 
TACCCCACAC TGTTCCTGGC TGTCTGGAAC TTCGGGGCAG TGGGCATGGT GTGCATCCAC 
TGGAAGGGTC CCCTGGTGCT CCAGCAGGCT TACCTCATTG TGATCAGCGC ACTCATGGCC 
CTGGTGTTCA TCAAGTACCT GCCGGAGTGG TCCGCTTGGG TCATCTTGGG CGCCATCTCT 
GTGTACGATC TCGTGGCTGT GCTGTGCCCC AAAGGGCCAC TGAGGATGCT GGTGGAAACT 
GCCCAGGAAA GAAACGAGCC CATATTTCCT GCCCTCATAT ACTCATCTGC CATGGTGTGG 
ACGGTAGGCA TGGCGAAGCT GGACCCCTCC TCTCAGGGAG CACTGCAGCT CCCTTACGAT 
CCAGAGATGG AAGAAGACTC CTATGACAGT TTTGGGGAAC CCTCATACCC TGAAGCCTTC 
GAAGCTCCCC AGCCTGGCTA CCCAGGGGAA GAGCCGGAGG AGGAGGAGGA AAGGGGTGTA 
AAGCTTGGTC TGGGAGACTT CATCTTCTAC AGCGTTCTGG TGGGCAAGGC AGCAGCCACA 
GGCAACGGAG ACTGGAGCAC GACGCTGGCC TGCTTTATCG CCATCCTCAT TGGCTTGTGT 
CTCACCCTCC TGCTGCTCGC CGTGTTCAAG AAGGCCCTGC CCGCCCTCCC CATCTCCATC 
ACCTTCGGGC TCATCTTTTA CTTCTCCACA GACAACCTGG TGCGTCCTTT CATGGACACG 
TTGGCCTCCC ACCAGCTCTA CATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Psen2 ( XM_017598939.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017454428.1 Rattus norvegicus presenilin 2 (Psen2), transcript variant X5, mRNA.

Price & Availability↑

CloneID	ORa07558
Clone ID Related Accession (Same CDS sequence)	XM_006250405.3 , XM_008769877.2 , XM_006250407.3 , XM_006250408.3 , NM_031087.2 , XM_017598939.1
Accession Version	XM_017598939.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1347bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	presenilin-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005112.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTCACAT TCATGGCCTC TGATAGCGAG GAAGAGGTGT GCGATGAGCG GACGTCCTTG 
ATGTCAGCCG AGAGCCCTAC ATCACGTTCC TGCCAGGACA GCAGGCCAGG CCCAGAGGAT 
GGAGAGAACA CTGCCCAGTG GAGGAGCCAG GAGAACGAGG ACGACTGTGA GGAGGACCCG 
GACCACTATG CCTGCAGTGG GGTTCCTGGG CGACCATCGG GCCTGGAGGA GGAGCTGACC 
CTCAAGTATG GGGCGAAGCA CGTGATCATG CTGTTCGTGC CTGTCACGCT GTGCATGATT 
GTGGTGGTGG CCACCATCAA GTCCGTGCGT TTCTACACGG AGAAGAACGG GCAGCTCATC 
TACACGCCCT TCACCGAGGA CACACCCTCT GTGGGCCAGC GGCTCCTCAA CTCCGTGCTG 
AACACTCTGA TCATGATCAG CGTCATTGTG GTCATGACTA TCTTCCTAGT GGTACTCTAC 
AAATATCGCT GTTACAAGTT CATCCATGGC TGGCTGATCA TGTCCTCCCT GATGCTCCTC 
TTCTTGTTCA CCTACATCTA CCTCGGGGAA GTGTTCAAGA CCTACAATGT GGCCATGGAC 
TACCCCACAC TGTTCCTGGC TGTCTGGAAC TTCGGGGCAG TGGGCATGGT GTGCATCCAC 
TGGAAGGGTC CCCTGGTGCT CCAGCAGGCT TACCTCATTG TGATCAGCGC ACTCATGGCC 
CTGGTGTTCA TCAAGTACCT GCCGGAGTGG TCCGCTTGGG TCATCTTGGG CGCCATCTCT 
GTGTACGATC TCGTGGCTGT GCTGTGCCCC AAAGGGCCAC TGAGGATGCT GGTGGAAACT 
GCCCAGGAAA GAAACGAGCC CATATTTCCT GCCCTCATAT ACTCATCTGC CATGGTGTGG 
ACGGTAGGCA TGGCGAAGCT GGACCCCTCC TCTCAGGGAG CACTGCAGCT CCCTTACGAT 
CCAGAGATGG AAGAAGACTC CTATGACAGT TTTGGGGAAC CCTCATACCC TGAAGCCTTC 
GAAGCTCCCC AGCCTGGCTA CCCAGGGGAA GAGCCGGAGG AGGAGGAGGA AAGGGGTGTA 
AAGCTTGGTC TGGGAGACTT CATCTTCTAC AGCGTTCTGG TGGGCAAGGC AGCAGCCACA 
GGCAACGGAG ACTGGAGCAC GACGCTGGCC TGCTTTATCG CCATCCTCAT TGGCTTGTGT 
CTCACCCTCC TGCTGCTCGC CGTGTTCAAG AAGGCCCTGC CCGCCCTCCC CATCTCCATC 
ACCTTCGGGC TCATCTTTTA CTTCTCCACA GACAACCTGG TGCGTCCTTT CATGGACACG 
TTGGCCTCCC ACCAGCTCTA CATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017454428.1
CDS	162..1508
Translation	MLTFMASDSEEEVCDERTSLMSAESPTSRSCQDSRPGPEDGENTAQWRSQENEDDCEEDPDHYACSGVPGRPSGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLLFLFTYIYLGEVFKTYNVAMDYPTLFLAVWNFGAVGMVCIHWKGPLVLQQAYLIVISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTVGMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEAFEAPQPGYPGEEPEEEEERGVKLGLGDFIFYSVLVGKAAATGNGDWSTTLACFIAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI

Target ORF information:

RefSeq Version	XM_017598939.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus presenilin 2 (Psen2), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017598939.1

ORF Insert Sequence:

ATGCTCACAT TCATGGCCTC TGATAGCGAG GAAGAGGTGT GCGATGAGCG GACGTCCTTG 
ATGTCAGCCG AGAGCCCTAC ATCACGTTCC TGCCAGGACA GCAGGCCAGG CCCAGAGGAT 
GGAGAGAACA CTGCCCAGTG GAGGAGCCAG GAGAACGAGG ACGACTGTGA GGAGGACCCG 
GACCACTATG CCTGCAGTGG GGTTCCTGGG CGACCATCGG GCCTGGAGGA GGAGCTGACC 
CTCAAGTATG GGGCGAAGCA CGTGATCATG CTGTTCGTGC CTGTCACGCT GTGCATGATT 
GTGGTGGTGG CCACCATCAA GTCCGTGCGT TTCTACACGG AGAAGAACGG GCAGCTCATC 
TACACGCCCT TCACCGAGGA CACACCCTCT GTGGGCCAGC GGCTCCTCAA CTCCGTGCTG 
AACACTCTGA TCATGATCAG CGTCATTGTG GTCATGACTA TCTTCCTAGT GGTACTCTAC 
AAATATCGCT GTTACAAGTT CATCCATGGC TGGCTGATCA TGTCCTCCCT GATGCTCCTC 
TTCTTGTTCA CCTACATCTA CCTCGGGGAA GTGTTCAAGA CCTACAATGT GGCCATGGAC 
TACCCCACAC TGTTCCTGGC TGTCTGGAAC TTCGGGGCAG TGGGCATGGT GTGCATCCAC 
TGGAAGGGTC CCCTGGTGCT CCAGCAGGCT TACCTCATTG TGATCAGCGC ACTCATGGCC 
CTGGTGTTCA TCAAGTACCT GCCGGAGTGG TCCGCTTGGG TCATCTTGGG CGCCATCTCT 
GTGTACGATC TCGTGGCTGT GCTGTGCCCC AAAGGGCCAC TGAGGATGCT GGTGGAAACT 
GCCCAGGAAA GAAACGAGCC CATATTTCCT GCCCTCATAT ACTCATCTGC CATGGTGTGG 
ACGGTAGGCA TGGCGAAGCT GGACCCCTCC TCTCAGGGAG CACTGCAGCT CCCTTACGAT 
CCAGAGATGG AAGAAGACTC CTATGACAGT TTTGGGGAAC CCTCATACCC TGAAGCCTTC 
GAAGCTCCCC AGCCTGGCTA CCCAGGGGAA GAGCCGGAGG AGGAGGAGGA AAGGGGTGTA 
AAGCTTGGTC TGGGAGACTT CATCTTCTAC AGCGTTCTGG TGGGCAAGGC AGCAGCCACA 
GGCAACGGAG ACTGGAGCAC GACGCTGGCC TGCTTTATCG CCATCCTCAT TGGCTTGTGT 
CTCACCCTCC TGCTGCTCGC CGTGTTCAAG AAGGCCCTGC CCGCCCTCCC CATCTCCATC 
ACCTTCGGGC TCATCTTTTA CTTCTCCACA GACAACCTGG TGCGTCCTTT CATGGACACG 
TTGGCCTCCC ACCAGCTCTA CATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Psen2 ( XM_006250410.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006250472.1 Rattus norvegicus presenilin 2 (Psen2), transcript variant X6, mRNA.

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CloneID	ORa35702
Clone ID Related Accession (Same CDS sequence)	XM_006250410.3
Accession Version	XM_006250410.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1344bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	presenilin-2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005112.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006250410.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTCACAT TCATGGCCTC TGATAGCGAG GAAGAGGTGT GCGATGAGCG GACGTCCTTG 
ATGTCAGCCG AGAGCCCTAC ATCACGTTCC TGCCAGGACA GCAGGCCAGG CCCAGAGGAT 
GGAGAGAACA CTGCCCAGTG GAGGAGCCAG GAGAACGAGG ACGACTGTGA GGAGGACCCG 
GACCACTATG CCTGCAGTGG GGTTCCTGGG CGACCATCGG GCCTGGAGGA GGAGCTGACC 
CTCAAGTATG GGGCGAAGCA CGTGATCATG CTGTTCGTGC CTGTCACGCT GTGCATGATT 
GTGGTGGTGG CCACCATCAA GTCCGTGCGT TTCTACACGG AGAAGAACGG GCAGCTCATC 
TACACGCCCT TCACCGAGGA CACACCCTCT GTGGGCCAGC GGCTCCTCAA CTCCGTGCTG 
AACACTCTGA TCATGATCAG CGTCATTGTG GTCATGACTA TCTTCCTAGT GGTACTCTAC 
AAATATCGCT GTTACAAGTT CATCCATGGC TGGCTGATCA TGTCCTCCCT GATGCTCCTC 
TTCTTGTTCA CCTACATCTA CCTCGGGGAA GTGTTCAAGA CCTACAATGT GGCCATGGAC 
TACCCCACAC TGTTCCTGGC TGTCTGGAAC TTCGGGGCAG TGGGCATGGT GTGCATCCAC 
TGGAAGGGTC CCCTGGTGCT CCAGCAGGCT TACCTCATTG TGATCAGCGC ACTCATGGCC 
CTGGTGTTCA TCAAGTACCT GCCGGAGTGG TCCGCTTGGG TCATCTTGGG CGCCATCTCT 
GTGTACGATC TCGTGGCTGT GCTGTGCCCC AAAGGGCCAC TGAGGATGCT GGTGGAAACT 
GCCCAGGAAA GAAACGAGCC CATATTTCCT GCCCTCATAT ACTCATCTGC CATGGTGTGG 
ACGGTAGGCA TGGCGAAGCT GGACCCCTCC TCTCAGGGAG CACTGCAGCT CCCTTACGAT 
CCAGAGATGG AAGACTCCTA TGACAGTTTT GGGGAACCCT CATACCCTGA AGCCTTCGAA 
GCTCCCCAGC CTGGCTACCC AGGGGAAGAG CCGGAGGAGG AGGAGGAAAG GGGTGTAAAG 
CTTGGTCTGG GAGACTTCAT CTTCTACAGC GTTCTGGTGG GCAAGGCAGC AGCCACAGGC 
AACGGAGACT GGAGCACGAC GCTGGCCTGC TTTATCGCCA TCCTCATTGG CTTGTGTCTC 
ACCCTCCTGC TGCTCGCCGT GTTCAAGAAG GCCCTGCCCG CCCTCCCCAT CTCCATCACC 
TTCGGGCTCA TCTTTTACTT CTCCACAGAC AACCTGGTGC GTCCTTTCAT GGACACGTTG 
GCCTCCCACC AGCTCTACAT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006250472.1
CDS	836..2179
Translation	MLTFMASDSEEEVCDERTSLMSAESPTSRSCQDSRPGPEDGENTAQWRSQENEDDCEEDPDHYACSGVPGRPSGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLLFLFTYIYLGEVFKTYNVAMDYPTLFLAVWNFGAVGMVCIHWKGPLVLQQAYLIVISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTVGMAKLDPSSQGALQLPYDPEMEDSYDSFGEPSYPEAFEAPQPGYPGEEPEEEEERGVKLGLGDFIFYSVLVGKAAATGNGDWSTTLACFIAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI

Target ORF information:

RefSeq Version	XM_006250410.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus presenilin 2 (Psen2), transcript variant X6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006250410.3

ORF Insert Sequence:

ATGCTCACAT TCATGGCCTC TGATAGCGAG GAAGAGGTGT GCGATGAGCG GACGTCCTTG 
ATGTCAGCCG AGAGCCCTAC ATCACGTTCC TGCCAGGACA GCAGGCCAGG CCCAGAGGAT 
GGAGAGAACA CTGCCCAGTG GAGGAGCCAG GAGAACGAGG ACGACTGTGA GGAGGACCCG 
GACCACTATG CCTGCAGTGG GGTTCCTGGG CGACCATCGG GCCTGGAGGA GGAGCTGACC 
CTCAAGTATG GGGCGAAGCA CGTGATCATG CTGTTCGTGC CTGTCACGCT GTGCATGATT 
GTGGTGGTGG CCACCATCAA GTCCGTGCGT TTCTACACGG AGAAGAACGG GCAGCTCATC 
TACACGCCCT TCACCGAGGA CACACCCTCT GTGGGCCAGC GGCTCCTCAA CTCCGTGCTG 
AACACTCTGA TCATGATCAG CGTCATTGTG GTCATGACTA TCTTCCTAGT GGTACTCTAC 
AAATATCGCT GTTACAAGTT CATCCATGGC TGGCTGATCA TGTCCTCCCT GATGCTCCTC 
TTCTTGTTCA CCTACATCTA CCTCGGGGAA GTGTTCAAGA CCTACAATGT GGCCATGGAC 
TACCCCACAC TGTTCCTGGC TGTCTGGAAC TTCGGGGCAG TGGGCATGGT GTGCATCCAC 
TGGAAGGGTC CCCTGGTGCT CCAGCAGGCT TACCTCATTG TGATCAGCGC ACTCATGGCC 
CTGGTGTTCA TCAAGTACCT GCCGGAGTGG TCCGCTTGGG TCATCTTGGG CGCCATCTCT 
GTGTACGATC TCGTGGCTGT GCTGTGCCCC AAAGGGCCAC TGAGGATGCT GGTGGAAACT 
GCCCAGGAAA GAAACGAGCC CATATTTCCT GCCCTCATAT ACTCATCTGC CATGGTGTGG 
ACGGTAGGCA TGGCGAAGCT GGACCCCTCC TCTCAGGGAG CACTGCAGCT CCCTTACGAT 
CCAGAGATGG AAGACTCCTA TGACAGTTTT GGGGAACCCT CATACCCTGA AGCCTTCGAA 
GCTCCCCAGC CTGGCTACCC AGGGGAAGAG CCGGAGGAGG AGGAGGAAAG GGGTGTAAAG 
CTTGGTCTGG GAGACTTCAT CTTCTACAGC GTTCTGGTGG GCAAGGCAGC AGCCACAGGC 
AACGGAGACT GGAGCACGAC GCTGGCCTGC TTTATCGCCA TCCTCATTGG CTTGTGTCTC 
ACCCTCCTGC TGCTCGCCGT GTTCAAGAAG GCCCTGCCCG CCCTCCCCAT CTCCATCACC 
TTCGGGCTCA TCTTTTACTT CTCCACAGAC AACCTGGTGC GTCCTTTCAT GGACACGTTG 
GCCTCCCACC AGCTCTACAT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A Presenilin/Notch1 pathway regulated by miR-375, miR-30a, and miR-34a mediates glucotoxicity induced-pancreatic beta cell apoptosis.
Scientific reports636136(2016 Nov)
Li Y,Zhang T,Zhou Y,Sun Y,Cao Y,Chang X,Zhu Y,Han X

Alzheimer-associated presenilin 2 gene is dysregulated in rat medial temporal lobe cortex after complete brain ischemia due to cardiac arrest.
Pharmacological reports : PR68(1)155-61(2016 Feb)
Pluta R,Kocki J,U?amek-Kozio? M,Bogucka-Kocka A,Gil-Kulik P,Januszewski S,Jab?o?ski M,Petniak A,Brzozowska J,Bogucki J,Furmaga-Jab?o?ska W,Czuczwar SJ

Partial loss of presenilin impairs age-dependent neuronal survival in the cerebral cortex.
The Journal of neuroscience : the official journal of the Society for Neuroscience34(48)15912-22(2014 Nov)
Watanabe H,Iqbal M,Zheng J,Wines-Samuelson M,Shen J

A role for the primary cilium in Notch signaling and epidermal differentiation during skin development.
Cell145(7)1129-41(2011 Jun)
Ezratty EJ,Stokes N,Chai S,Shah AS,Williams SE,Fuchs E

Presenilin 2 modulates endoplasmic reticulum (ER)-mitochondria interactions and Ca2+ cross-talk.
Proceedings of the National Academy of Sciences of the United States of America108(7)2777-82(2011 Feb)
Zampese E,Fasolato C,Kipanyula MJ,Bortolozzi M,Pozzan T,Pizzo P

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Psen2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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