Grm7 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Grm7
Entrez Gene ID	81672
Full Name	glutamate metabotropic receptor 7
General protein information	Preferred Names glutamate metabotropic receptor 7 Names metabotropic glutamate receptor 7 glutamate receptor, metabotropic 7 mGluR7 metabotropic glutamate receptor mGluR7 metabotropic glutamate receptor subtype 7b
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 4 Map Location: 4q41
Summary	G-protein coupled receptor that inhibits glutamate release; acts via cAMP inhibitory and Ca+2 channel inhibitory pathways [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_017592907.1	XP_017448396.1	metabotropic glutamate receptor 7 isoform X1
XM_017592908.1	XP_017448397.1	metabotropic glutamate receptor 7 isoform X1
NM_031040.1	NP_112302.1	metabotropic glutamate receptor 7 precursor

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	grm7	NP_001106479.1
Bos taurus (cattle)	GRM7	NP_001069523.2
Mus musculus (house mouse)	Grm7	NP_796302.2
Rattus norvegicus (Norway rat)	Grm7	NP_112302.1
Canis lupus familiaris (dog)	LOC484674	XP_003432796.1
Gallus gallus (chicken)	GRM7	XP_004944775.1
Homo sapiens (human)	GRM7	NP_000835.1
Caenorhabditis elegans (roundworm)	mgl-3	NP_001076735.2
Pan troglodytes (chimpanzee)	GRM7	XP_516252.2
Danio rerio (zebrafish)	LOC100331190	XP_002666402.3

Gene Ontology
Bibliography

Related articles in PubMed

Metabotropic Glutamate Receptor 7 (mGluR7) as a Target for Modulating Pain-evoked Activities of Neurons in the Hippocampal CA3 Region of Rats.
Wei X, Yang D, Shi T, Wang J, Deng Y, Qiao X, Yang C, Xu M
CNS & neurological disorders drug targets16(5)610-616(2017)

Metabotropic Glutamate Receptors 7 within the Nucleus Accumbens are Involved in Relief Learning in Rats.
Kahl E, Fendt M
Current neuropharmacology14(5)405-12(2016)

Beta-arrestin1 and 2 differently modulate metabotropic glutamate receptor 7 signaling in rat developmental sevoflurane-induced neuronal apoptosis.
Wang WY, Wu XM, Jia LJ, Zhang HH, Cai F, Mao H, Xu WC, Chen L, Zhang J, Hu SF
Neuroscience313199-212(2016 Jan)

Constitutive activity of metabotropic glutamate receptor 7.
Kammermeier PJ
BMC neuroscience1617(2015 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Study indicates that functional activation of accumbal mGluR7 has antinociceptive effects that interfere with relief learning
Title: Metabotropic Glutamate Receptors 7 within the Nucleus Accumbens are Involved in Relief Learning in Rats.

Results suggested that beta-arr1 and 2 may differently modulate mGluR7 signaling in developmental sevoflurane neurotoxicity
Title: Beta-arrestin1 and 2 differently modulate metabotropic glutamate receptor 7 signaling in rat developmental sevoflurane-induced neuronal apoptosis.

Study demonstrated that mGluR7 can signal constitutively (in the absence of agonist) when expressed in neurons
Title: Constitutive activity of metabotropic glutamate receptor 7.

Agonist-induced dephosphorylation of mGluR7 is regulated by PP1.
Title: Regulation of metabotropic glutamate receptor 7 (mGluR7) internalization and surface expression by Ser/Thr protein phosphatase 1.

Activation of mGluR7 can produce antiparkinsonian-like effects in rats.
Title: Contribution of the mGluR7 receptor to antiparkinsonian-like effects in rats: a behavioral study with the selective agonist AMN082.

The following Grm7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Grm7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa13355	NM_031040.1 Latest version!	Rattus norvegicus glutamate metabotropic receptor 7 (Grm7), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$538.30 $769.00
ORa61016	XM_017592907.1 Latest version!	Rattus norvegicus glutamate metabotropic receptor 7 (Grm7), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
ORa61016	XM_017592908.1 Latest version!	Rattus norvegicus glutamate metabotropic receptor 7 (Grm7), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Grm7 ( NM_031040.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_112302.1 Rattus norvegicus glutamate metabotropic receptor 7 (Grm7), mRNA.

Price & Availability↑

CloneID	ORa13355
Clone ID Related Accession (Same CDS sequence)	NM_031040.1
Accession Version	NM_031040.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2748bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-14
Organism	Rattus norvegicus(Norway rat)
Product	metabotropic glutamate receptor 7 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from D16817.1. On Dec 17, 2003 this sequence version replaced XM_346722.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: D16817.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGTCCAGC TGGGGAAGCT GCTCCGCGTC CTGACTTTGA TGAAGTTCCC CTGCTGCGTG 
CTGGAGGTGC TCCTGTGCGT GCTGGCGGCG GCGGCGCGCG GCCAGGAGAT GTACGCCCCG 
CACTCGATCC GGATCGAGGG GGACGTCACC CTTGGGGGGT TGTTCCCAGT GCACGCCAAG 
GGTCCCAGCG GAGTGCCCTG CGGCGACATC AAGAGGGAGA ATGGGATCCA CAGGCTGGAA 
GCTATGCTTT ATGCCCTGGA CCAGATCAAC AGCGATCCCA ACCTGCTGCC CAATGTAACG 
TTAGGCGCGC GGATCCTGGA CACTTGTTCC AGGGACACTT ATGCGCTCGA ACAGTCGCTC 
ACTTTCGTCC AGGCGCTTAT CCAGAAGGAC ACCTCCGACG TGCGTTGCAC CAACGGAGAG 
CCCCCGGTTT TCGTCAAGCC AGAGAAAGTA GTTGGAGTGA TTGGGGCTTC GGGGAGCTCC 
GTCTCCATCA TGGTAGCCAA CATCTTGAGG CTTTTTCAGA TCCCTCAGAT TAGTTATGCA 
TCCACGGCTC CTGAACTCAG TGATGACCGG CGCTATGACT TCTTCTCTCG AGTGGTCCCG 
CCTGATTCCT TCCAAGCCCA GGCGATGGTT GACATTGTAA AGGCTTTGGG CTGGAATTAC 
GTGTCTACTC TTGCATCTGA AGGAAGCTAT GGAGAGAAAG GTGTGGAGTC CTTCACACAG 
ATTTCCAAAG AGGCAGGTGG GCTCTGCATT GCCCAGTCCG TGAGAATCCC CCAAGAGCGC 
AAAGACAGGA CCATTGACTT TGATAGAATT ATCAAACAGC TCTTGGACAC TCCCAACTCC 
AGGGCCGTCG TGATTTTTGC CAACGATGAG GATATAAAGC AGATCCTTGC CGCCGCCAAA 
AGAGCTGACC AAGTAGGCCA TTTTCTCTGG GTCGGGTCAG ACAGCTGGGG TTCCAAAATC 
AACCCACTGC ATCAGCACGA AGATATTGCG GAAGGAGCCA TAACAATCCA GCCTAAAAGG 
GCAACCGTGG AAGGATTTGA TGCTTACTTC ACATCCCGGA CACTTGAAAA CAACAGGAGA 
AATGTATGGT TTGCCGAATA CTGGGAAGAA AACTTCAACT GCAAGTTGAC AATTAGTGGG 
TCCAAAAAAG AAGACACAGA TCGCAAATGC ACAGGACAGG AGCGAATTGG AAAAGACTCC 
AATTATGAGC AGGAAGGTAA AGTACAGTTT GTGATTGATG CTGTCTATGC CATGGCCCAT 
GCTCTTCATC ACATGAACAA GGATCTGTGT GCTGACTACC GCGGAGTGTG CCCAGAGATG 
GAGCAAGCAG GCGGCAAGAA GTTGTTGAAG TATATCCGCC ATGTTAACTT CAATGGTAGT 
GCTGGAACCC CAGTAATGTT TAACAAAAAT GGCGATGCTC CAGGGCGTTA TGACATCTTC 
CAATACCAGA CAACAAACAC AACCAACCCT GGTTATCGTC TCATTGGGCA GTGGACAGAT 
GAACTTCAGC TCAATATAGA GGACATGCAG TGGGGCAAAG GAGTCCGAGA GATCCCATCC 
TCTGTGTGTA CATTGCCATG CAAGCCTGGG CAAAGGAAGA AGACACAGAA GGGAACGCCT 
TGCTGCTGGA CCTGTGAGCC CTGTGATGGA TACCAGTATC AGTTTGATGA GATGACCTGT 
CAGCATTGTC CCTACGACCA GAGGCCCAAT GAGAACCGAA CTGGCTGTCA GAACATCCCA 
ATCATCAAAC TGGAGTGGCA CTCCCCCTGG GCTGTCATTC CTGTCTTCCT GGCAATGTTG 
GGGATCATTG CCACCATCTT TGTCATGGCA ACTTTCATCC GCTACAATGA CACACCCATT 
GTCAGGGCAT CTGGGCGGGA ACTCAGCTAT GTTTTATTGA CAGGCATCTT TCTCTGCTAT 
ATCATCACCT TCCTAATGAT TGCCAAACCA GATGTGGCAG TGTGTTCTTT CCGACGTGTC 
TTCTTGGGCT TGGGCATGTG TATTAGTTAT GCTGCCCTTT TAACAAAGAC CAATCGGATT 
TATCGCATAT TCGAGCAGGG CAAGAAATCG GTGACAGCTC CCAGACTCAT AAGCCCAACG 
TCACAACTGG CGATCACTTC CAGTTTAATA TCGGTGCAGC TTCTAGGTGT CTTCATTTGG 
TTTGGGGTTG ACCCCCCCAA CATTATCATA GACTACGATG AGCATAAGAC CATGAACCCA 
GAACAAGCAA GGGGTGTTCT CAAATGTGAC ATCACAGACC TTCAAATCAT TTGTTCCCTG 
GGATATAGCA TTCTTCTCAT GGTCACATGT ACTGTGTATG CCATCAAGAC TCGGGGCGTA 
CCAGAGAATT TTAATGAAGC CAAGCCCATT GGGTTCACTA TGTACACGAC GTGTATCGTA 
TGGCTTGCCT TCATCCCAAT ATTTTTTGGC ACAGCGCAGT CAGCAGAAAA GCTCTACATA 
CAAACTACCA CGCTTACAAT CTCCATGAAC CTAAGTGCGT CAGTGGCGCT GGGAATGCTA 
TACATGCCGA AAGTGTACAT CATCATTTTC CACCCTGAAC TCAATGTCCA GAAACGGAAG 
CGAAGCTTCA AGGCCGTAGT CACAGCAGCC ACCATGTCAT CAAGGCTGTC ACACAAACCC 
AGTGACAGGC CCAACGGTGA GGCAAAGACA GAACTCTGTG AAAATGTAGA CCCAAACAGC 
CCTGCTGCAA AAAAGAAGTA TGTCAGTTAT AATAACCTGG TTATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_112302.1
CDS	398..3145
Translation	MVQLGKLLRVLTLMKFPCCVLEVLLCVLAAAARGQEMYAPHSIRIEGDVTLGGLFPVHAKGPSGVPCGDIKRENGIHRLEAMLYALDQINSDPNLLPNVTLGARILDTCSRDTYALEQSLTFVQALIQKDTSDVRCTNGEPPVFVKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYASTAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGSYGEKGVESFTQISKEAGGLCIAQSVRIPQERKDRTIDFDRIIKQLLDTPNSRAVVIFANDEDIKQILAAAKRADQVGHFLWVGSDSWGSKINPLHQHEDIAEGAITIQPKRATVEGFDAYFTSRTLENNRRNVWFAEYWEENFNCKLTISGSKKEDTDRKCTGQERIGKDSNYEQEGKVQFVIDAVYAMAHALHHMNKDLCADYRGVCPEMEQAGGKKLLKYIRHVNFNGSAGTPVMFNKNGDAPGRYDIFQYQTTNTTNPGYRLIGQWTDELQLNIEDMQWGKGVREIPSSVCTLPCKPGQRKKTQKGTPCCWTCEPCDGYQYQFDEMTCQHCPYDQRPNENRTGCQNIPIIKLEWHSPWAVIPVFLAMLGIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLMIAKPDVAVCSFRRVFLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLISPTSQLAITSSLISVQLLGVFIWFGVDPPNIIIDYDEHKTMNPEQARGVLKCDITDLQIICSLGYSILLMVTCTVYAIKTRGVPENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEKLYIQTTTLTISMNLSASVALGMLYMPKVYIIIFHPELNVQKRKRSFKAVVTAATMSSRLSHKPSDRPNGEAKTELCENVDPNSPAAKKKYVSYNNLVI

Target ORF information:

RefSeq Version	NM_031040.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus glutamate metabotropic receptor 7 (Grm7), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031040.1

ORF Insert Sequence:

ATGGTCCAGC TGGGGAAGCT GCTCCGCGTC CTGACTTTGA TGAAGTTCCC CTGCTGCGTG 
CTGGAGGTGC TCCTGTGCGT GCTGGCGGCG GCGGCGCGCG GCCAGGAGAT GTACGCCCCG 
CACTCGATCC GGATCGAGGG GGACGTCACC CTTGGGGGGT TGTTCCCAGT GCACGCCAAG 
GGTCCCAGCG GAGTGCCCTG CGGCGACATC AAGAGGGAGA ATGGGATCCA CAGGCTGGAA 
GCTATGCTTT ATGCCCTGGA CCAGATCAAC AGCGATCCCA ACCTGCTGCC CAATGTAACG 
TTAGGCGCGC GGATCCTGGA CACTTGTTCC AGGGACACTT ATGCGCTCGA ACAGTCGCTC 
ACTTTCGTCC AGGCGCTTAT CCAGAAGGAC ACCTCCGACG TGCGTTGCAC CAACGGAGAG 
CCCCCGGTTT TCGTCAAGCC AGAGAAAGTA GTTGGAGTGA TTGGGGCTTC GGGGAGCTCC 
GTCTCCATCA TGGTAGCCAA CATCTTGAGG CTTTTTCAGA TCCCTCAGAT TAGTTATGCA 
TCCACGGCTC CTGAACTCAG TGATGACCGG CGCTATGACT TCTTCTCTCG AGTGGTCCCG 
CCTGATTCCT TCCAAGCCCA GGCGATGGTT GACATTGTAA AGGCTTTGGG CTGGAATTAC 
GTGTCTACTC TTGCATCTGA AGGAAGCTAT GGAGAGAAAG GTGTGGAGTC CTTCACACAG 
ATTTCCAAAG AGGCAGGTGG GCTCTGCATT GCCCAGTCCG TGAGAATCCC CCAAGAGCGC 
AAAGACAGGA CCATTGACTT TGATAGAATT ATCAAACAGC TCTTGGACAC TCCCAACTCC 
AGGGCCGTCG TGATTTTTGC CAACGATGAG GATATAAAGC AGATCCTTGC CGCCGCCAAA 
AGAGCTGACC AAGTAGGCCA TTTTCTCTGG GTCGGGTCAG ACAGCTGGGG TTCCAAAATC 
AACCCACTGC ATCAGCACGA AGATATTGCG GAAGGAGCCA TAACAATCCA GCCTAAAAGG 
GCAACCGTGG AAGGATTTGA TGCTTACTTC ACATCCCGGA CACTTGAAAA CAACAGGAGA 
AATGTATGGT TTGCCGAATA CTGGGAAGAA AACTTCAACT GCAAGTTGAC AATTAGTGGG 
TCCAAAAAAG AAGACACAGA TCGCAAATGC ACAGGACAGG AGCGAATTGG AAAAGACTCC 
AATTATGAGC AGGAAGGTAA AGTACAGTTT GTGATTGATG CTGTCTATGC CATGGCCCAT 
GCTCTTCATC ACATGAACAA GGATCTGTGT GCTGACTACC GCGGAGTGTG CCCAGAGATG 
GAGCAAGCAG GCGGCAAGAA GTTGTTGAAG TATATCCGCC ATGTTAACTT CAATGGTAGT 
GCTGGAACCC CAGTAATGTT TAACAAAAAT GGCGATGCTC CAGGGCGTTA TGACATCTTC 
CAATACCAGA CAACAAACAC AACCAACCCT GGTTATCGTC TCATTGGGCA GTGGACAGAT 
GAACTTCAGC TCAATATAGA GGACATGCAG TGGGGCAAAG GAGTCCGAGA GATCCCATCC 
TCTGTGTGTA CATTGCCATG CAAGCCTGGG CAAAGGAAGA AGACACAGAA GGGAACGCCT 
TGCTGCTGGA CCTGTGAGCC CTGTGATGGA TACCAGTATC AGTTTGATGA GATGACCTGT 
CAGCATTGTC CCTACGACCA GAGGCCCAAT GAGAACCGAA CTGGCTGTCA GAACATCCCA 
ATCATCAAAC TGGAGTGGCA CTCCCCCTGG GCTGTCATTC CTGTCTTCCT GGCAATGTTG 
GGGATCATTG CCACCATCTT TGTCATGGCA ACTTTCATCC GCTACAATGA CACACCCATT 
GTCAGGGCAT CTGGGCGGGA ACTCAGCTAT GTTTTATTGA CAGGCATCTT TCTCTGCTAT 
ATCATCACCT TCCTAATGAT TGCCAAACCA GATGTGGCAG TGTGTTCTTT CCGACGTGTC 
TTCTTGGGCT TGGGCATGTG TATTAGTTAT GCTGCCCTTT TAACAAAGAC CAATCGGATT 
TATCGCATAT TCGAGCAGGG CAAGAAATCG GTGACAGCTC CCAGACTCAT AAGCCCAACG 
TCACAACTGG CGATCACTTC CAGTTTAATA TCGGTGCAGC TTCTAGGTGT CTTCATTTGG 
TTTGGGGTTG ACCCCCCCAA CATTATCATA GACTACGATG AGCATAAGAC CATGAACCCA 
GAACAAGCAA GGGGTGTTCT CAAATGTGAC ATCACAGACC TTCAAATCAT TTGTTCCCTG 
GGATATAGCA TTCTTCTCAT GGTCACATGT ACTGTGTATG CCATCAAGAC TCGGGGCGTA 
CCAGAGAATT TTAATGAAGC CAAGCCCATT GGGTTCACTA TGTACACGAC GTGTATCGTA 
TGGCTTGCCT TCATCCCAAT ATTTTTTGGC ACAGCGCAGT CAGCAGAAAA GCTCTACATA 
CAAACTACCA CGCTTACAAT CTCCATGAAC CTAAGTGCGT CAGTGGCGCT GGGAATGCTA 
TACATGCCGA AAGTGTACAT CATCATTTTC CACCCTGAAC TCAATGTCCA GAAACGGAAG 
CGAAGCTTCA AGGCCGTAGT CACAGCAGCC ACCATGTCAT CAAGGCTGTC ACACAAACCC 
AGTGACAGGC CCAACGGTGA GGCAAAGACA GAACTCTGTG AAAATGTAGA CCCAAACAGC 
CCTGCTGCAA AAAAGAAGTA TGTCAGTTAT AATAACCTGG TTATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Grm7 ( XM_017592907.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017448396.1 Rattus norvegicus glutamate metabotropic receptor 7 (Grm7), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa61016
Clone ID Related Accession (Same CDS sequence)	XM_017592907.1 , XM_017592908.1
Accession Version	XM_017592907.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2769bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	metabotropic glutamate receptor 7 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTCCAGC TGGGGAAGCT GCTCCGCGTC CTGACTTTGA TGAAGTTCCC CTGCTGCGTG 
CTGGAGGTGC TCCTGTGCGT GCTGGCGGCG GCGGCGCGCG GCCAGGAGAT GTACGCCCCG 
CACTCGATCC GGATCGAGGG GGACGTCACC CTTGGGGGGT TGTTCCCAGT GCACGCCAAG 
GGTCCCAGCG GAGTGCCCTG CGGCGACATC AAGAGGGAGA ATGGGATCCA CAGGCTGGAA 
GCTATGCTTT ATGCCCTGGA CCAGATCAAC AGCGATCCCA ACCTGCTGCC CAATGTAACG 
TTAGGCGCGC GGATCCTGGA CACTTGTTCC AGGGACACTT ATGCGCTCGA ACAGTCGCTC 
ACTTTCGTCC AGGCGCTTAT CCAGAAGGAC ACCTCCGACG TGCGTTGCAC CAACGGAGAG 
CCCCCGGTTT TCGTCAAGCC AGAGAAAGTA GTTGGAGTGA TTGGGGCTTC GGGGAGCTCC 
GTCTCCATCA TGGTAGCCAA CATCTTGAGG CTTTTTCAGA TCCCTCAGAT TAGTTATGCA 
TCCACGGCTC CTGAACTCAG TGATGACCGG CGCTATGACT TCTTCTCTCG AGTGGTCCCG 
CCTGATTCCT TCCAAGCCCA GGCGATGGTT GACATTGTAA AGGCTTTGGG CTGGAATTAC 
GTGTCTACTC TTGCATCTGA AGGAAGCTAT GGAGAGAAAG GTGTGGAGTC CTTCACACAG 
ATTTCCAAAG AGGCAGGTGG GCTCTGCATT GCCCAGTCCG TGAGAATCCC CCAAGAGCGC 
AAAGACAGGA CCATTGACTT TGATAGAATT ATCAAACAGC TCTTGGACAC TCCCAACTCC 
AGGGCCGTCG TGATTTTTGC CAACGATGAG GATATAAAGC AGATCCTTGC CGCCGCCAAA 
AGAGCTGACC AAGTAGGCCA TTTTCTCTGG GTCGGGTCAG ACAGCTGGGG TTCCAAAATC 
AACCCACTGC ATCAGCACGA AGATATTGCG GAAGGAGCCA TAACAATCCA GCCTAAAAGG 
GCAACCGTGG AAGGATTTGA TGCTTACTTC ACATCCCGGA CACTTGAAAA CAACAGGAGA 
AATGTATGGT TTGCCGAATA CTGGGAAGAA AACTTCAACT GCAAGTTGAC AATTAGTGGG 
TCCAAAAAAG AAGACACAGA TCGCAAATGC ACAGGACAGG AGCGAATTGG AAAAGACTCC 
AATTATGAGC AGGAAGGTAA AGTACAGTTT GTGATTGATG CTGTCTATGC CATGGCCCAT 
GCTCTTCATC ACATGAACAA GGATCTGTGT GCTGACTACC GCGGAGTGTG CCCAGAGATG 
GAGCAAGCAG GCGGCAAGAA GTTGTTGAAG TATATCCGCC ATGTTAACTT CAATGGTAGT 
GCTGGAACCC CAGTAATGTT TAACAAAAAT GGCGATGCTC CAGGGCGTTA TGACATCTTC 
CAATACCAGA CAACAAACAC AACCAACCCT GGTTATCGTC TCATTGGGCA GTGGACAGAT 
GAACTTCAGC TCAATATAGA GGACATGCAG TGGGGCAAAG GAGTCCGAGA GATCCCATCC 
TCTGTGTGTA CATTGCCATG CAAGCCTGGG CAAAGGAAGA AGACACAGAA GGGAACGCCT 
TGCTGCTGGA CCTGTGAGCC CTGTGATGGA TACCAGTATC AGTTTGATGA GATGACCTGT 
CAGCATTGTC CCTACGACCA GAGGCCCAAT GAGAACCGAA CTGGCTGTCA GAACATCCCA 
ATCATCAAAC TGGAGTGGCA CTCCCCCTGG GCTGTCATTC CTGTCTTCCT GGCAATGTTG 
GGGATCATTG CCACCATCTT TGTCATGGCA ACTTTCATCC GCTACAATGA CACACCCATT 
GTCAGGGCAT CTGGGCGGGA ACTCAGCTAT GTTTTATTGA CAGGCATCTT TCTCTGCTAT 
ATCATCACCT TCCTAATGAT TGCCAAACCA GATGTGGCAG TGTGTTCTTT CCGACGTGTC 
TTCTTGGGCT TGGGCATGTG TATTAGTTAT GCTGCCCTTT TAACAAAGAC CAATCGGATT 
TATCGCATAT TCGAGCAGGG CAAGAAATCG GTGACAGCTC CCAGACTCAT AAGCCCAACG 
TCACAACTGG CGATCACTTC CAGTTTAATA TCGGTGCAGC TTCTAGGTGT CTTCATTTGG 
TTTGGGGTTG ACCCCCCCAA CATTATCATA GACTACGATG AGCATAAGAC CATGAACCCA 
GAACAAGCAA GGGGTGTTCT CAAATGTGAC ATCACAGACC TTCAAATCAT TTGTTCCCTG 
GGATATAGCA TTCTTCTCAT GGTCACATGT ACTGTGTATG CCATCAAGAC TCGGGGCGTA 
CCAGAGAATT TTAATGAAGC CAAGCCCATT GGGTTCACTA TGTACACGAC GTGTATCGTA 
TGGCTTGCCT TCATCCCAAT ATTTTTTGGC ACAGCGCAGT CAGCAGAAAA GCTCTACATA 
CAAACTACCA CGCTTACAAT CTCCATGAAC CTAAGTGCGT CAGTGGCGCT GGGAATGCTA 
TACATGCCGA AAGTGTACAT CATCATTTTC CACCCTGAAC TCAATGTCCA GAAACGGAAG 
CGAAGCTTCA AGGCCGTAGT CACAGCAGCC ACCATGTCAT CAAGGCTGTC ACACAAACCC 
AGTGACAGGC CCAACGGTGA GGCAAAGACA GAACTCTGTG AAAATGTAGA CCCAAACAAC 
TGTATACCAC CAGTAAGAAA GAGTGTACAA AAGTCCGTAA CTTGGTACAC TATCCCACCA 
ACAGTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017448396.1
CDS	385..3153
Translation	MVQLGKLLRVLTLMKFPCCVLEVLLCVLAAAARGQEMYAPHSIRIEGDVTLGGLFPVHAKGPSGVPCGDIKRENGIHRLEAMLYALDQINSDPNLLPNVTLGARILDTCSRDTYALEQSLTFVQALIQKDTSDVRCTNGEPPVFVKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYASTAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGSYGEKGVESFTQISKEAGGLCIAQSVRIPQERKDRTIDFDRIIKQLLDTPNSRAVVIFANDEDIKQILAAAKRADQVGHFLWVGSDSWGSKINPLHQHEDIAEGAITIQPKRATVEGFDAYFTSRTLENNRRNVWFAEYWEENFNCKLTISGSKKEDTDRKCTGQERIGKDSNYEQEGKVQFVIDAVYAMAHALHHMNKDLCADYRGVCPEMEQAGGKKLLKYIRHVNFNGSAGTPVMFNKNGDAPGRYDIFQYQTTNTTNPGYRLIGQWTDELQLNIEDMQWGKGVREIPSSVCTLPCKPGQRKKTQKGTPCCWTCEPCDGYQYQFDEMTCQHCPYDQRPNENRTGCQNIPIIKLEWHSPWAVIPVFLAMLGIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLMIAKPDVAVCSFRRVFLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLISPTSQLAITSSLISVQLLGVFIWFGVDPPNIIIDYDEHKTMNPEQARGVLKCDITDLQIICSLGYSILLMVTCTVYAIKTRGVPENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEKLYIQTTTLTISMNLSASVALGMLYMPKVYIIIFHPELNVQKRKRSFKAVVTAATMSSRLSHKPSDRPNGEAKTELCENVDPNNCIPPVRKSVQKSVTWYTIPPTV

Target ORF information:

RefSeq Version	XM_017592907.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus glutamate metabotropic receptor 7 (Grm7), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017592907.1

ORF Insert Sequence:

ATGGTCCAGC TGGGGAAGCT GCTCCGCGTC CTGACTTTGA TGAAGTTCCC CTGCTGCGTG 
CTGGAGGTGC TCCTGTGCGT GCTGGCGGCG GCGGCGCGCG GCCAGGAGAT GTACGCCCCG 
CACTCGATCC GGATCGAGGG GGACGTCACC CTTGGGGGGT TGTTCCCAGT GCACGCCAAG 
GGTCCCAGCG GAGTGCCCTG CGGCGACATC AAGAGGGAGA ATGGGATCCA CAGGCTGGAA 
GCTATGCTTT ATGCCCTGGA CCAGATCAAC AGCGATCCCA ACCTGCTGCC CAATGTAACG 
TTAGGCGCGC GGATCCTGGA CACTTGTTCC AGGGACACTT ATGCGCTCGA ACAGTCGCTC 
ACTTTCGTCC AGGCGCTTAT CCAGAAGGAC ACCTCCGACG TGCGTTGCAC CAACGGAGAG 
CCCCCGGTTT TCGTCAAGCC AGAGAAAGTA GTTGGAGTGA TTGGGGCTTC GGGGAGCTCC 
GTCTCCATCA TGGTAGCCAA CATCTTGAGG CTTTTTCAGA TCCCTCAGAT TAGTTATGCA 
TCCACGGCTC CTGAACTCAG TGATGACCGG CGCTATGACT TCTTCTCTCG AGTGGTCCCG 
CCTGATTCCT TCCAAGCCCA GGCGATGGTT GACATTGTAA AGGCTTTGGG CTGGAATTAC 
GTGTCTACTC TTGCATCTGA AGGAAGCTAT GGAGAGAAAG GTGTGGAGTC CTTCACACAG 
ATTTCCAAAG AGGCAGGTGG GCTCTGCATT GCCCAGTCCG TGAGAATCCC CCAAGAGCGC 
AAAGACAGGA CCATTGACTT TGATAGAATT ATCAAACAGC TCTTGGACAC TCCCAACTCC 
AGGGCCGTCG TGATTTTTGC CAACGATGAG GATATAAAGC AGATCCTTGC CGCCGCCAAA 
AGAGCTGACC AAGTAGGCCA TTTTCTCTGG GTCGGGTCAG ACAGCTGGGG TTCCAAAATC 
AACCCACTGC ATCAGCACGA AGATATTGCG GAAGGAGCCA TAACAATCCA GCCTAAAAGG 
GCAACCGTGG AAGGATTTGA TGCTTACTTC ACATCCCGGA CACTTGAAAA CAACAGGAGA 
AATGTATGGT TTGCCGAATA CTGGGAAGAA AACTTCAACT GCAAGTTGAC AATTAGTGGG 
TCCAAAAAAG AAGACACAGA TCGCAAATGC ACAGGACAGG AGCGAATTGG AAAAGACTCC 
AATTATGAGC AGGAAGGTAA AGTACAGTTT GTGATTGATG CTGTCTATGC CATGGCCCAT 
GCTCTTCATC ACATGAACAA GGATCTGTGT GCTGACTACC GCGGAGTGTG CCCAGAGATG 
GAGCAAGCAG GCGGCAAGAA GTTGTTGAAG TATATCCGCC ATGTTAACTT CAATGGTAGT 
GCTGGAACCC CAGTAATGTT TAACAAAAAT GGCGATGCTC CAGGGCGTTA TGACATCTTC 
CAATACCAGA CAACAAACAC AACCAACCCT GGTTATCGTC TCATTGGGCA GTGGACAGAT 
GAACTTCAGC TCAATATAGA GGACATGCAG TGGGGCAAAG GAGTCCGAGA GATCCCATCC 
TCTGTGTGTA CATTGCCATG CAAGCCTGGG CAAAGGAAGA AGACACAGAA GGGAACGCCT 
TGCTGCTGGA CCTGTGAGCC CTGTGATGGA TACCAGTATC AGTTTGATGA GATGACCTGT 
CAGCATTGTC CCTACGACCA GAGGCCCAAT GAGAACCGAA CTGGCTGTCA GAACATCCCA 
ATCATCAAAC TGGAGTGGCA CTCCCCCTGG GCTGTCATTC CTGTCTTCCT GGCAATGTTG 
GGGATCATTG CCACCATCTT TGTCATGGCA ACTTTCATCC GCTACAATGA CACACCCATT 
GTCAGGGCAT CTGGGCGGGA ACTCAGCTAT GTTTTATTGA CAGGCATCTT TCTCTGCTAT 
ATCATCACCT TCCTAATGAT TGCCAAACCA GATGTGGCAG TGTGTTCTTT CCGACGTGTC 
TTCTTGGGCT TGGGCATGTG TATTAGTTAT GCTGCCCTTT TAACAAAGAC CAATCGGATT 
TATCGCATAT TCGAGCAGGG CAAGAAATCG GTGACAGCTC CCAGACTCAT AAGCCCAACG 
TCACAACTGG CGATCACTTC CAGTTTAATA TCGGTGCAGC TTCTAGGTGT CTTCATTTGG 
TTTGGGGTTG ACCCCCCCAA CATTATCATA GACTACGATG AGCATAAGAC CATGAACCCA 
GAACAAGCAA GGGGTGTTCT CAAATGTGAC ATCACAGACC TTCAAATCAT TTGTTCCCTG 
GGATATAGCA TTCTTCTCAT GGTCACATGT ACTGTGTATG CCATCAAGAC TCGGGGCGTA 
CCAGAGAATT TTAATGAAGC CAAGCCCATT GGGTTCACTA TGTACACGAC GTGTATCGTA 
TGGCTTGCCT TCATCCCAAT ATTTTTTGGC ACAGCGCAGT CAGCAGAAAA GCTCTACATA 
CAAACTACCA CGCTTACAAT CTCCATGAAC CTAAGTGCGT CAGTGGCGCT GGGAATGCTA 
TACATGCCGA AAGTGTACAT CATCATTTTC CACCCTGAAC TCAATGTCCA GAAACGGAAG 
CGAAGCTTCA AGGCCGTAGT CACAGCAGCC ACCATGTCAT CAAGGCTGTC ACACAAACCC 
AGTGACAGGC CCAACGGTGA GGCAAAGACA GAACTCTGTG AAAATGTAGA CCCAAACAAC 
TGTATACCAC CAGTAAGAAA GAGTGTACAA AAGTCCGTAA CTTGGTACAC TATCCCACCA 
ACAGTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Grm7 ( XM_017592908.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017448397.1 Rattus norvegicus glutamate metabotropic receptor 7 (Grm7), transcript variant X2, mRNA.

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CloneID	ORa61016
Clone ID Related Accession (Same CDS sequence)	XM_017592907.1 , XM_017592908.1
Accession Version	XM_017592908.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2769bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	metabotropic glutamate receptor 7 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTCCAGC TGGGGAAGCT GCTCCGCGTC CTGACTTTGA TGAAGTTCCC CTGCTGCGTG 
CTGGAGGTGC TCCTGTGCGT GCTGGCGGCG GCGGCGCGCG GCCAGGAGAT GTACGCCCCG 
CACTCGATCC GGATCGAGGG GGACGTCACC CTTGGGGGGT TGTTCCCAGT GCACGCCAAG 
GGTCCCAGCG GAGTGCCCTG CGGCGACATC AAGAGGGAGA ATGGGATCCA CAGGCTGGAA 
GCTATGCTTT ATGCCCTGGA CCAGATCAAC AGCGATCCCA ACCTGCTGCC CAATGTAACG 
TTAGGCGCGC GGATCCTGGA CACTTGTTCC AGGGACACTT ATGCGCTCGA ACAGTCGCTC 
ACTTTCGTCC AGGCGCTTAT CCAGAAGGAC ACCTCCGACG TGCGTTGCAC CAACGGAGAG 
CCCCCGGTTT TCGTCAAGCC AGAGAAAGTA GTTGGAGTGA TTGGGGCTTC GGGGAGCTCC 
GTCTCCATCA TGGTAGCCAA CATCTTGAGG CTTTTTCAGA TCCCTCAGAT TAGTTATGCA 
TCCACGGCTC CTGAACTCAG TGATGACCGG CGCTATGACT TCTTCTCTCG AGTGGTCCCG 
CCTGATTCCT TCCAAGCCCA GGCGATGGTT GACATTGTAA AGGCTTTGGG CTGGAATTAC 
GTGTCTACTC TTGCATCTGA AGGAAGCTAT GGAGAGAAAG GTGTGGAGTC CTTCACACAG 
ATTTCCAAAG AGGCAGGTGG GCTCTGCATT GCCCAGTCCG TGAGAATCCC CCAAGAGCGC 
AAAGACAGGA CCATTGACTT TGATAGAATT ATCAAACAGC TCTTGGACAC TCCCAACTCC 
AGGGCCGTCG TGATTTTTGC CAACGATGAG GATATAAAGC AGATCCTTGC CGCCGCCAAA 
AGAGCTGACC AAGTAGGCCA TTTTCTCTGG GTCGGGTCAG ACAGCTGGGG TTCCAAAATC 
AACCCACTGC ATCAGCACGA AGATATTGCG GAAGGAGCCA TAACAATCCA GCCTAAAAGG 
GCAACCGTGG AAGGATTTGA TGCTTACTTC ACATCCCGGA CACTTGAAAA CAACAGGAGA 
AATGTATGGT TTGCCGAATA CTGGGAAGAA AACTTCAACT GCAAGTTGAC AATTAGTGGG 
TCCAAAAAAG AAGACACAGA TCGCAAATGC ACAGGACAGG AGCGAATTGG AAAAGACTCC 
AATTATGAGC AGGAAGGTAA AGTACAGTTT GTGATTGATG CTGTCTATGC CATGGCCCAT 
GCTCTTCATC ACATGAACAA GGATCTGTGT GCTGACTACC GCGGAGTGTG CCCAGAGATG 
GAGCAAGCAG GCGGCAAGAA GTTGTTGAAG TATATCCGCC ATGTTAACTT CAATGGTAGT 
GCTGGAACCC CAGTAATGTT TAACAAAAAT GGCGATGCTC CAGGGCGTTA TGACATCTTC 
CAATACCAGA CAACAAACAC AACCAACCCT GGTTATCGTC TCATTGGGCA GTGGACAGAT 
GAACTTCAGC TCAATATAGA GGACATGCAG TGGGGCAAAG GAGTCCGAGA GATCCCATCC 
TCTGTGTGTA CATTGCCATG CAAGCCTGGG CAAAGGAAGA AGACACAGAA GGGAACGCCT 
TGCTGCTGGA CCTGTGAGCC CTGTGATGGA TACCAGTATC AGTTTGATGA GATGACCTGT 
CAGCATTGTC CCTACGACCA GAGGCCCAAT GAGAACCGAA CTGGCTGTCA GAACATCCCA 
ATCATCAAAC TGGAGTGGCA CTCCCCCTGG GCTGTCATTC CTGTCTTCCT GGCAATGTTG 
GGGATCATTG CCACCATCTT TGTCATGGCA ACTTTCATCC GCTACAATGA CACACCCATT 
GTCAGGGCAT CTGGGCGGGA ACTCAGCTAT GTTTTATTGA CAGGCATCTT TCTCTGCTAT 
ATCATCACCT TCCTAATGAT TGCCAAACCA GATGTGGCAG TGTGTTCTTT CCGACGTGTC 
TTCTTGGGCT TGGGCATGTG TATTAGTTAT GCTGCCCTTT TAACAAAGAC CAATCGGATT 
TATCGCATAT TCGAGCAGGG CAAGAAATCG GTGACAGCTC CCAGACTCAT AAGCCCAACG 
TCACAACTGG CGATCACTTC CAGTTTAATA TCGGTGCAGC TTCTAGGTGT CTTCATTTGG 
TTTGGGGTTG ACCCCCCCAA CATTATCATA GACTACGATG AGCATAAGAC CATGAACCCA 
GAACAAGCAA GGGGTGTTCT CAAATGTGAC ATCACAGACC TTCAAATCAT TTGTTCCCTG 
GGATATAGCA TTCTTCTCAT GGTCACATGT ACTGTGTATG CCATCAAGAC TCGGGGCGTA 
CCAGAGAATT TTAATGAAGC CAAGCCCATT GGGTTCACTA TGTACACGAC GTGTATCGTA 
TGGCTTGCCT TCATCCCAAT ATTTTTTGGC ACAGCGCAGT CAGCAGAAAA GCTCTACATA 
CAAACTACCA CGCTTACAAT CTCCATGAAC CTAAGTGCGT CAGTGGCGCT GGGAATGCTA 
TACATGCCGA AAGTGTACAT CATCATTTTC CACCCTGAAC TCAATGTCCA GAAACGGAAG 
CGAAGCTTCA AGGCCGTAGT CACAGCAGCC ACCATGTCAT CAAGGCTGTC ACACAAACCC 
AGTGACAGGC CCAACGGTGA GGCAAAGACA GAACTCTGTG AAAATGTAGA CCCAAACAAC 
TGTATACCAC CAGTAAGAAA GAGTGTACAA AAGTCCGTAA CTTGGTACAC TATCCCACCA 
ACAGTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017448397.1
CDS	385..3153
Translation	MVQLGKLLRVLTLMKFPCCVLEVLLCVLAAAARGQEMYAPHSIRIEGDVTLGGLFPVHAKGPSGVPCGDIKRENGIHRLEAMLYALDQINSDPNLLPNVTLGARILDTCSRDTYALEQSLTFVQALIQKDTSDVRCTNGEPPVFVKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYASTAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGSYGEKGVESFTQISKEAGGLCIAQSVRIPQERKDRTIDFDRIIKQLLDTPNSRAVVIFANDEDIKQILAAAKRADQVGHFLWVGSDSWGSKINPLHQHEDIAEGAITIQPKRATVEGFDAYFTSRTLENNRRNVWFAEYWEENFNCKLTISGSKKEDTDRKCTGQERIGKDSNYEQEGKVQFVIDAVYAMAHALHHMNKDLCADYRGVCPEMEQAGGKKLLKYIRHVNFNGSAGTPVMFNKNGDAPGRYDIFQYQTTNTTNPGYRLIGQWTDELQLNIEDMQWGKGVREIPSSVCTLPCKPGQRKKTQKGTPCCWTCEPCDGYQYQFDEMTCQHCPYDQRPNENRTGCQNIPIIKLEWHSPWAVIPVFLAMLGIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLMIAKPDVAVCSFRRVFLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLISPTSQLAITSSLISVQLLGVFIWFGVDPPNIIIDYDEHKTMNPEQARGVLKCDITDLQIICSLGYSILLMVTCTVYAIKTRGVPENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEKLYIQTTTLTISMNLSASVALGMLYMPKVYIIIFHPELNVQKRKRSFKAVVTAATMSSRLSHKPSDRPNGEAKTELCENVDPNNCIPPVRKSVQKSVTWYTIPPTV

Target ORF information:

RefSeq Version	XM_017592908.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus glutamate metabotropic receptor 7 (Grm7), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017592908.1

ORF Insert Sequence:

ATGGTCCAGC TGGGGAAGCT GCTCCGCGTC CTGACTTTGA TGAAGTTCCC CTGCTGCGTG 
CTGGAGGTGC TCCTGTGCGT GCTGGCGGCG GCGGCGCGCG GCCAGGAGAT GTACGCCCCG 
CACTCGATCC GGATCGAGGG GGACGTCACC CTTGGGGGGT TGTTCCCAGT GCACGCCAAG 
GGTCCCAGCG GAGTGCCCTG CGGCGACATC AAGAGGGAGA ATGGGATCCA CAGGCTGGAA 
GCTATGCTTT ATGCCCTGGA CCAGATCAAC AGCGATCCCA ACCTGCTGCC CAATGTAACG 
TTAGGCGCGC GGATCCTGGA CACTTGTTCC AGGGACACTT ATGCGCTCGA ACAGTCGCTC 
ACTTTCGTCC AGGCGCTTAT CCAGAAGGAC ACCTCCGACG TGCGTTGCAC CAACGGAGAG 
CCCCCGGTTT TCGTCAAGCC AGAGAAAGTA GTTGGAGTGA TTGGGGCTTC GGGGAGCTCC 
GTCTCCATCA TGGTAGCCAA CATCTTGAGG CTTTTTCAGA TCCCTCAGAT TAGTTATGCA 
TCCACGGCTC CTGAACTCAG TGATGACCGG CGCTATGACT TCTTCTCTCG AGTGGTCCCG 
CCTGATTCCT TCCAAGCCCA GGCGATGGTT GACATTGTAA AGGCTTTGGG CTGGAATTAC 
GTGTCTACTC TTGCATCTGA AGGAAGCTAT GGAGAGAAAG GTGTGGAGTC CTTCACACAG 
ATTTCCAAAG AGGCAGGTGG GCTCTGCATT GCCCAGTCCG TGAGAATCCC CCAAGAGCGC 
AAAGACAGGA CCATTGACTT TGATAGAATT ATCAAACAGC TCTTGGACAC TCCCAACTCC 
AGGGCCGTCG TGATTTTTGC CAACGATGAG GATATAAAGC AGATCCTTGC CGCCGCCAAA 
AGAGCTGACC AAGTAGGCCA TTTTCTCTGG GTCGGGTCAG ACAGCTGGGG TTCCAAAATC 
AACCCACTGC ATCAGCACGA AGATATTGCG GAAGGAGCCA TAACAATCCA GCCTAAAAGG 
GCAACCGTGG AAGGATTTGA TGCTTACTTC ACATCCCGGA CACTTGAAAA CAACAGGAGA 
AATGTATGGT TTGCCGAATA CTGGGAAGAA AACTTCAACT GCAAGTTGAC AATTAGTGGG 
TCCAAAAAAG AAGACACAGA TCGCAAATGC ACAGGACAGG AGCGAATTGG AAAAGACTCC 
AATTATGAGC AGGAAGGTAA AGTACAGTTT GTGATTGATG CTGTCTATGC CATGGCCCAT 
GCTCTTCATC ACATGAACAA GGATCTGTGT GCTGACTACC GCGGAGTGTG CCCAGAGATG 
GAGCAAGCAG GCGGCAAGAA GTTGTTGAAG TATATCCGCC ATGTTAACTT CAATGGTAGT 
GCTGGAACCC CAGTAATGTT TAACAAAAAT GGCGATGCTC CAGGGCGTTA TGACATCTTC 
CAATACCAGA CAACAAACAC AACCAACCCT GGTTATCGTC TCATTGGGCA GTGGACAGAT 
GAACTTCAGC TCAATATAGA GGACATGCAG TGGGGCAAAG GAGTCCGAGA GATCCCATCC 
TCTGTGTGTA CATTGCCATG CAAGCCTGGG CAAAGGAAGA AGACACAGAA GGGAACGCCT 
TGCTGCTGGA CCTGTGAGCC CTGTGATGGA TACCAGTATC AGTTTGATGA GATGACCTGT 
CAGCATTGTC CCTACGACCA GAGGCCCAAT GAGAACCGAA CTGGCTGTCA GAACATCCCA 
ATCATCAAAC TGGAGTGGCA CTCCCCCTGG GCTGTCATTC CTGTCTTCCT GGCAATGTTG 
GGGATCATTG CCACCATCTT TGTCATGGCA ACTTTCATCC GCTACAATGA CACACCCATT 
GTCAGGGCAT CTGGGCGGGA ACTCAGCTAT GTTTTATTGA CAGGCATCTT TCTCTGCTAT 
ATCATCACCT TCCTAATGAT TGCCAAACCA GATGTGGCAG TGTGTTCTTT CCGACGTGTC 
TTCTTGGGCT TGGGCATGTG TATTAGTTAT GCTGCCCTTT TAACAAAGAC CAATCGGATT 
TATCGCATAT TCGAGCAGGG CAAGAAATCG GTGACAGCTC CCAGACTCAT AAGCCCAACG 
TCACAACTGG CGATCACTTC CAGTTTAATA TCGGTGCAGC TTCTAGGTGT CTTCATTTGG 
TTTGGGGTTG ACCCCCCCAA CATTATCATA GACTACGATG AGCATAAGAC CATGAACCCA 
GAACAAGCAA GGGGTGTTCT CAAATGTGAC ATCACAGACC TTCAAATCAT TTGTTCCCTG 
GGATATAGCA TTCTTCTCAT GGTCACATGT ACTGTGTATG CCATCAAGAC TCGGGGCGTA 
CCAGAGAATT TTAATGAAGC CAAGCCCATT GGGTTCACTA TGTACACGAC GTGTATCGTA 
TGGCTTGCCT TCATCCCAAT ATTTTTTGGC ACAGCGCAGT CAGCAGAAAA GCTCTACATA 
CAAACTACCA CGCTTACAAT CTCCATGAAC CTAAGTGCGT CAGTGGCGCT GGGAATGCTA 
TACATGCCGA AAGTGTACAT CATCATTTTC CACCCTGAAC TCAATGTCCA GAAACGGAAG 
CGAAGCTTCA AGGCCGTAGT CACAGCAGCC ACCATGTCAT CAAGGCTGTC ACACAAACCC 
AGTGACAGGC CCAACGGTGA GGCAAAGACA GAACTCTGTG AAAATGTAGA CCCAAACAAC 
TGTATACCAC CAGTAAGAAA GAGTGTACAA AAGTCCGTAA CTTGGTACAC TATCCCACCA 
ACAGTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Metabotropic Glutamate Receptor 7 (mGluR7) as a Target for Modulating Pain-evoked Activities of Neurons in the Hippocampal CA3 Region of Rats.
CNS & neurological disorders drug targets16(5)610-616(2017)
Wei X,Yang D,Shi T,Wang J,Deng Y,Qiao X,Yang C,Xu M

Metabotropic Glutamate Receptors 7 within the Nucleus Accumbens are Involved in Relief Learning in Rats.
Current neuropharmacology14(5)405-12(2016)
Kahl E,Fendt M

Beta-arrestin1 and 2 differently modulate metabotropic glutamate receptor 7 signaling in rat developmental sevoflurane-induced neuronal apoptosis.
Neuroscience313199-212(2016 Jan)
Wang WY,Wu XM,Jia LJ,Zhang HH,Cai F,Mao H,Xu WC,Chen L,Zhang J,Hu SF

Constitutive activity of metabotropic glutamate receptor 7.
BMC neuroscience1617(2015 Mar)
Kammermeier PJ

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Grm7 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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