Abcc6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Abcc6
Entrez Gene ID	81642
Full Name	ATP binding cassette subfamily C member 6
Synonyms	Mrp6
General protein information	Preferred Names ATP binding cassette subfamily C member 6 Names multidrug resistance-associated protein 6 ATP-binding cassette sub-family C member 6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 ATP-binding cassette, subfamily C (CFTR/MRP), member 6 MLP-1 MRP-like protein 1 liver multidrug resistance-associated protein 6
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q22
Summary	human homolog acts as a Mg-ATP-dependent efflux pump that transports glutathione S-conjugates and mediates a low level of resistance to some anticancer agents [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_017589769.1	XP_017445258.1	multidrug resistance-associated protein 6 isoform X1
XM_006229159.2	XP_006229221.1	multidrug resistance-associated protein 6 isoform X2
XM_008759419.2	XP_008757641.1	multidrug resistance-associated protein 6 isoform X2
NM_031013.1	NP_112275.1	multidrug resistance-associated protein 6
XM_017589770.1	XP_017445259.1	multidrug resistance-associated protein 6 isoform X3

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Abcc6	NP_061265.2
Homo sapiens (human)	ABCC6	NP_001162.4
Bos taurus (cattle)	ABCC6	NP_001263299.1
Pan troglodytes (chimpanzee)	ABCC6	XP_001145741.2
	LOC717875	XP_001109862.2
Canis lupus familiaris (dog)	ABCC6	XP_547113.4
Gallus gallus (chicken)	ABCC6	NP_001239009.1
Rattus norvegicus (Norway rat)	Abcc6	NP_112275.1

Gene Ontology
Bibliography

Related articles in PubMed

Abcc6 Knockout Rat Model Highlights the?Role of Liver in PPi Homeostasis in?Pseudoxanthoma Elasticum.
Li Q, Kingman J, van de Wetering K, Tannouri S, Sundberg JP, Uitto J
The Journal of investigative dermatology137(5)1025-1032(2017 May)

ABCC6-mediated ATP secretion by the liver is the main source of the mineralization inhibitor inorganic pyrophosphate in the systemic circulation-brief report.
Jansen RS, Duijst S, Mahakena S, Sommer D, Szeri F, V?radi A, Plomp A, Bergen AA, Oude Elferink RP, Borst P, van de Wetering K
Arteriosclerosis, thrombosis, and vascular biology34(9)1985-9(2014 Sep)

Chronic kidney disease results in deficiency of ABCC6, the novel inhibitor of vascular calcification.
Lau WL, Liu S, Vaziri ND
American journal of nephrology40(1)51-5(2014)

Effect of inflammation on molecular targets and drug transporters.
Hanafy S, El-Kadi AO, Jamali F
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques15(3)361-75(2012)

A mouse model of ?-thalassemia shows a liver-specific down-regulation of Abcc6 expression.
Martin L, Douet V, VanWart CM, Heller MB, Le Saux O
The American journal of pathology178(2)774-83(2011 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This study suggests a critical role of hepatic ABCC6 in contributing to plasma inorganic pyrophosphate levels, identifying liver as a target of molecular correction to counteract ectopic mineralization in pseudoxanthoma elasticum
Title: Abcc6 Knockout Rat Model Highlights the?Role of Liver in PPi Homeostasis in?Pseudoxanthoma Elasticum.

In the absence of transfected rat ABCC6, HeLa and HEK293 cells released almost no ATP, but on induction of rat ABCC6, they released substantial amounts of ATP into the cell culture medium.
Title: ABCC6-mediated ATP secretion by the liver is the main source of the mineralization inhibitor inorganic pyrophosphate in the systemic circulation-brief report.

In a rat model of CKD, ABCC6 protein expression was decreased in liver and kidney, however mRNA levels were unchanged.
Title: Chronic kidney disease results in deficiency of ABCC6, the novel inhibitor of vascular calcification.

The following Abcc6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Abcc6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa56864	XM_017589769.1 Latest version!	Rattus norvegicus ATP binding cassette subfamily C member 6 (Abcc6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$727.30 $1039.00
ORa56865	XM_017589770.1 Latest version!	Rattus norvegicus ATP binding cassette subfamily C member 6 (Abcc6), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$643.30 $919.00
ORa07381	NM_031013.1 Latest version!	Rattus norvegicus ATP binding cassette subfamily C member 6 (Abcc6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$811.30 $1159.00
ORa22787	XM_008759419.2 Latest version!	Rattus norvegicus ATP binding cassette subfamily C member 6 (Abcc6), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$727.30 $1039.00
ORa22787	XM_006229159.2 Latest version!	Rattus norvegicus ATP binding cassette subfamily C member 6 (Abcc6), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$727.30 $1039.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Abcc6 ( XM_017589769.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017445258.1 Rattus norvegicus ATP binding cassette subfamily C member 6 (Abcc6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa56864
Clone ID Related Accession (Same CDS sequence)	XM_017589769.1
Accession Version	XM_017589769.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4404bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	multidrug resistance-associated protein 6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACGGAG AGCACTCAAT GGCCACGCCT GGAGAGTCCT GCGCAGGCCT GAGGGTCTGG 
AACCAGACAG AACAGGAGCC TGTGGCCTAT CACTTGCTCA ACCTGTGCTT CCTGCGAGCC 
GCCGGGAGCT GGGTGCCCCC CATGTACCTC TGGGTCCTTG GCCCCATCTA CCTCCTCTAC 
ATCCATCGCC ATGGCTGCTG CTACCTCCGG ATGTCCCGCC TCTTCAAAAT CAAAATGGTG 
CTCGGCTTTG CCCTCATCCT TCTCTACACC TTCAACGCGG CCGTGCCTCT CTGGAGGATC 
CACCGGGGCA TGCCCCAGGC CCCAGAGCTT CTCATTCACC CTACCGTGTG GCTCACCACC 
ATGAGCTTCG CCACCTTCCT GATCCACATG GAGAGAAAGA AGGGGGTCCG TGCATCTGGG 
TTGTTGTTCG GGTACTGGCT GCTCTGCTGC CTCGTGCCAG CCATCGACAC TGTCCAGCAG 
GCCTCCGCAG GGAGCTTCCG CCAGGAGCCC CTCCACCACC TGGCCACCTA CCTGTGCTTG 
TCCCTGGTGG TGGCAGAGCT GGTGCTGTCT TGTCTGGTAG ACCAGCCACC CTTCTTCTCG 
GAAGACTCCA AGCCATTGAA TCCATGTCCA GAGGCCGAGG CCTCTTTTCC CTCCAAGGCC 
ATGTTCTGGT GGGCCTCTGG ACTGCTATGG AAGGGCTACA GGAAACTGCT GGGGCCAAAA 
GACCTCTGGT CACTTGAGAG AGAAAACTCT TCAGAAGAAC TTGTTTCCCA GCTGGAAAGA 
GAATGGAGGA GGAACTTCAG TGAGCTGCCG GGGCACAAAG GGCACAGTGG TATGGGGACC 
CCCGAGACAG AGGCCTTCCT GCAGCCAGAG AGGAGCCAGC GGGGCCCGCT GCTCAGGGCT 
ATCTGGCGTG TGTTCCGGTC CACTTTCCTG CTGGGGACCC TCAGCCTGGT CATTAGCGAT 
GCCTTCAGGT TTGCTGTTCC CAAGCTCCTC AGTCTGTTTC TGGAGTTCAT GGGCGACCTC 
GAGTCCTCGG CTTGGACGGG CTGGCTCCTG GCTGTGCTGA TGTTCTTGTC GGCCTGCCTA 
CAGACACTGT TTGAACAGCA GTACATGTAC AGAGTCAAGG TCCTGCAGAT GAGGCTGCGA 
ACAGCCATCA CTGGCCTGGT GTACAGAAAG GTCCTGGTCC TGTCCAGTGG TTCCAGAAAG 
TCCAGTGCAG CAGGGGACGT GGTCAACCTG GTGTCAGTGG ACGTACAGCG GCTGGTCGAG 
AGCATCCTCC ACCTCAACGG GCTGTGGCTG CTCTTCCTGT GGATCATTGT GTGCTTTGTC 
TACCTGTGGC AGCTCCTTGG GCCCTCTGCC CTCACAGCCG TTGCTGTCTT CCTGAGCCTT 
CTCCCCCTGA ACTTCTTCAT TACCAAGAAG AGGAGCTTCC ATCAGGAAGA ACAGATGAGG 
CAGAAGGCCT CCCGAGCACG GCTCACCAGC TCCATGCTCA GAACTGTGAG AACCATCAAG 
TCCCACGGCT GGGAGTGTGC CTTCCTGGAG CGACTCCTGC ATATCCGGGG CCAGGAGCTA 
GGTGCCCTGA AGACCTCCGC CTTCCTCTTC TCTGTGTCTC TCGTGTCCTT CCAAGTGTCT 
ACATTTCTGG TGGCGCTGGT TGTGTTTGCT GTCCACACCC TGGTGGCAGA GGACAACGCC 
ATGGATGCGG AGAAGGCGTT TGTGACGCTC ACGGTGCTCA GCATCCTTAA CAAAGCCCAG 
GCCTTCCTCC CCTTCTCTGT GCACTGCCTC GTTCAGGCTC GGGTGTCCTT TGACCGCCTA 
GCTGCTTTCC TGTGCCTGGA AGAAGTAGAC CCCAATGGCA TGGTCTTGAG TCCCTCCAGA 
TGCTCCTCGA AGGATCGAAT TTCTATACAC AATGGCACCT TCGCTTGGTC CCAGGAGAGC 
CCGCCCTGCC TGCACGGGAT CAACCTCACC GTGCCCCAGG GCTGTCTGCT GGCTGTTGTG 
GGTCCAGTGG GGGCTGGAAA GTCCTCCCTG CTGTCTGCCC TGCTTGGGGA GCTGTTGAAG 
GTAGAAGGGT CTGTGAGCAT TGAGGGTTCC GTGGCCTACG TGCCTCAGGA GGCTTGGGTC 
CAGAATACCT CTGTGGTGGA GAATGTGTGC TTCAGGCAGG AGCTGGATCT GCCATGGTTG 
CAGGAAGTTC TAGAAGCCTG TGCCTTGGGG TCTGATGTGG CCAGCTTCCC TGCAGGAGTT 
CACACCCCAG TAGGGGAGCA GGGCATGAAT CTTTCTGGGG GCCAGAAGCA GCGGCTGAGC 
TTGGCTCGGG CTGTGTACAG AAGGGCTGCT GTGTACCTGA TGGATGACCC CCTAGCAGCC 
CTGGATGCGC ATGTCAGCCA GGAAGTCTTC AAACAGGTCA TTGGCCCCAG TGGACTTCTC 
CAAGGTACGA CTCGGATCCT TGTAACACAC ACGCTGCATG TCCTGCCCCA AGCTGACCAG 
ATCCTGGTGC TGGCCAATGG GACCATCGCA GAGATGGGCT CCTACCAAGA CCTTCTGCAT 
AGGAACGGAG CCCTGGTGGG TCTTCTGGAT GGAGCCAGAC AGCCTGCAGG CGAAGGAGAA 
GGAGAAGCAC ATGCTGCAGC CACCAGTGAT GACCTTGGAG GCTTTTCTGG AGGTGGGACG 
CCCACGCGCA GACCAGAGAG GCCCAGACCC AGTGACGCAG CCCCTGTGAA GGGCAGTACT 
TCAGAGGCAC AGATGGAGCC TTCTCTGGAT GACGTTGAGG TCACTGGACT GACAGCAGGA 
GAGGACAGTG TGCAGTATGG CCGGGTGAAG AGCGCCACAT ACCTGAGCTA CCTGCGGGCG 
GTGGGCACAC CGCTCTGCAC CTACACCCTG TTCCTCTTCC TCTGCCAGCA AGTGGCGTCC 
TTCTGCCAAG GCTACTGGCT GAGCCTCTGG GCCGACGACC CGGTCGTGGA TGGGAAGCAG 
ATGCATTCAG CCCTGCGTGG CTCCATCTTT GGACTCCTTG GCTGTCTGCA AGCCATCGGA 
CTGTTTGCCT CCATGGCTGC GGTGTTCCTG GGTGGAGCCC GAGCTTCATG CCTGCTTTTC 
CGGAGCCTCC TCTGGGACGT GGCTCGCTCT CCCATTGGCT TCTTTGAGCG CACACCAGTC 
GGGAACCTGC TGAACCGTTT TTCCAAGGAG ACGGACATAG TGGATGTGGA CATCCCAGAC 
AAGATGAGGA CCCTGCTGAC CTATGCCTTT GGACTCCTGG AGGTTGGCCT GGCAGTGTCG 
ATGGCCACAC CACTGGCTAT TGTGGCCATC CTACCTCTTA TGCTCCTTTA TGCTGGGTTT 
CAGAGCCTCT ACGTGGCCAC ATGTTGCCAG CTGAGACGCC TGGAGTCGGC CAGTTACTCC 
TCAGTGTGTT CCCATCTGGC TGAGACCTTC CAGGGCAGTC AGGTGGTCAG GGCCTTCCAG 
GCCCAGGGGC CCTTCACAGC TCAGCACGAT GCCCTCATGG ATGAGAACCA GAGGATCAGT 
TTCCCGAGGC TGGTGGCTGA CAGGTGGCTG GCTGCCAACC TGGAGCTCCT GGGGAATGGC 
CTGGTGTTTG TGGCCGCTAC ATGTGCTGTG CTGAGCAAGG CTCACCTGAG TGCTGGCCTC 
GCGGGCTTCT CGGTTTCTGC TGCCCTCCAG GTAACACAGA CTCTGCAGTG GGTGGTCCGC 
AGCTGGACAG ATCTGGAGAA CAGCATGGTG GCCGTGGAGC GAGTACAGGA CTACGTTCAC 
ACCCCCAAGG AGGCTCCCTG GAGGCTGCCC TCCTCTGCAG CCCAGCCTCT CTGGCCCTGT 
GGGGGACAGA TTGAGTTCCG AGACTTTGGG CTCAGACACC GACCAGAGCT GCCCATGGCT 
GTGCAGGGTG TGTCCCTGAA GATCCATGCA GGGGAGAAGG TGGGCATCGT GGGCAGGACA 
GGGGCCGGGA AGTCCTCCCT GACTTGGGGC CTGCTGCGGC TTCAGGAGGC CACTGAGGGT 
GGTATTTGGA TCGATGGGGT CCCCATCACC GACATGGGGC TGCACACACT GCGGTCCAGA 
ATCACCATCA TCCCTCAGGA CCCTGTCCTG TTCCCGGGCT CGCTGCGGAT GAACCTGGAC 
CTGCTTCAGG AGAACACAGA TGAGGGCATC TGGGCAGCGC TGGAGACGGT GCAGCTCAAG 
GCCTTCGTGA CCAGCCTGCC TGGCCAGCTG CAGTATGAGT GCTCAGGCCA GGGAGATGAC 
CTGAGTGTGG GTCAGAAGCA GCTCCTGTGT CTGGCACGTG CCCTTCTCCG GAAAACCCAG 
ATCCTCATCC TGGATGAAGC CACTGCCTCC GTGGACCCAG GGACGGAGAT ACAGATGCAG 
GCGGCCCTCG AGCGCTGGTT TGCACAGTGT ACAGTGCTGC TCATTGCTCA CCGCCTGCGC 
TCCGTGATGA ACTGCGCCAG ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017445258.1
CDS	81..4484
Translation	MNGEHSMATPGESCAGLRVWNQTEQEPVAYHLLNLCFLRAAGSWVPPMYLWVLGPIYLLYIHRHGCCYLRMSRLFKIKMVLGFALILLYTFNAAVPLWRIHRGMPQAPELLIHPTVWLTTMSFATFLIHMERKKGVRASGLLFGYWLLCCLVPAIDTVQQASAGSFRQEPLHHLATYLCLSLVVAELVLSCLVDQPPFFSEDSKPLNPCPEAEASFPSKAMFWWASGLLWKGYRKLLGPKDLWSLERENSSEELVSQLEREWRRNFSELPGHKGHSGMGTPETEAFLQPERSQRGPLLRAIWRVFRSTFLLGTLSLVISDAFRFAVPKLLSLFLEFMGDLESSAWTGWLLAVLMFLSACLQTLFEQQYMYRVKVLQMRLRTAITGLVYRKVLVLSSGSRKSSAAGDVVNLVSVDVQRLVESILHLNGLWLLFLWIIVCFVYLWQLLGPSALTAVAVFLSLLPLNFFITKKRSFHQEEQMRQKASRARLTSSMLRTVRTIKSHGWECAFLERLLHIRGQELGALKTSAFLFSVSLVSFQVSTFLVALVVFAVHTLVAEDNAMDAEKAFVTLTVLSILNKAQAFLPFSVHCLVQARVSFDRLAAFLCLEEVDPNGMVLSPSRCSSKDRISIHNGTFAWSQESPPCLHGINLTVPQGCLLAVVGPVGAGKSSLLSALLGELLKVEGSVSIEGSVAYVPQEAWVQNTSVVENVCFRQELDLPWLQEVLEACALGSDVASFPAGVHTPVGEQGMNLSGGQKQRLSLARAVYRRAAVYLMDDPLAALDAHVSQEVFKQVIGPSGLLQGTTRILVTHTLHVLPQADQILVLANGTIAEMGSYQDLLHRNGALVGLLDGARQPAGEGEGEAHAAATSDDLGGFSGGGTPTRRPERPRPSDAAPVKGSTSEAQMEPSLDDVEVTGLTAGEDSVQYGRVKSATYLSYLRAVGTPLCTYTLFLFLCQQVASFCQGYWLSLWADDPVVDGKQMHSALRGSIFGLLGCLQAIGLFASMAAVFLGGARASCLLFRSLLWDVARSPIGFFERTPVGNLLNRFSKETDIVDVDIPDKMRTLLTYAFGLLEVGLAVSMATPLAIVAILPLMLLYAGFQSLYVATCCQLRRLESASYSSVCSHLAETFQGSQVVRAFQAQGPFTAQHDALMDENQRISFPRLVADRWLAANLELLGNGLVFVAATCAVLSKAHLSAGLAGFSVSAALQVTQTLQWVVRSWTDLENSMVAVERVQDYVHTPKEAPWRLPSSAAQPLWPCGGQIEFRDFGLRHRPELPMAVQGVSLKIHAGEKVGIVGRTGAGKSSLTWGLLRLQEATEGGIWIDGVPITDMGLHTLRSRITIIPQDPVLFPGSLRMNLDLLQENTDEGIWAALETVQLKAFVTSLPGQLQYECSGQGDDLSVGQKQLLCLARALLRKTQILILDEATASVDPGTEIQMQAALERWFAQCTVLLIAHRLRSVMNCAR

Target ORF information:

RefSeq Version	XM_017589769.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ATP binding cassette subfamily C member 6 (Abcc6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017589769.1

ORF Insert Sequence:

ATGAACGGAG AGCACTCAAT GGCCACGCCT GGAGAGTCCT GCGCAGGCCT GAGGGTCTGG 
AACCAGACAG AACAGGAGCC TGTGGCCTAT CACTTGCTCA ACCTGTGCTT CCTGCGAGCC 
GCCGGGAGCT GGGTGCCCCC CATGTACCTC TGGGTCCTTG GCCCCATCTA CCTCCTCTAC 
ATCCATCGCC ATGGCTGCTG CTACCTCCGG ATGTCCCGCC TCTTCAAAAT CAAAATGGTG 
CTCGGCTTTG CCCTCATCCT TCTCTACACC TTCAACGCGG CCGTGCCTCT CTGGAGGATC 
CACCGGGGCA TGCCCCAGGC CCCAGAGCTT CTCATTCACC CTACCGTGTG GCTCACCACC 
ATGAGCTTCG CCACCTTCCT GATCCACATG GAGAGAAAGA AGGGGGTCCG TGCATCTGGG 
TTGTTGTTCG GGTACTGGCT GCTCTGCTGC CTCGTGCCAG CCATCGACAC TGTCCAGCAG 
GCCTCCGCAG GGAGCTTCCG CCAGGAGCCC CTCCACCACC TGGCCACCTA CCTGTGCTTG 
TCCCTGGTGG TGGCAGAGCT GGTGCTGTCT TGTCTGGTAG ACCAGCCACC CTTCTTCTCG 
GAAGACTCCA AGCCATTGAA TCCATGTCCA GAGGCCGAGG CCTCTTTTCC CTCCAAGGCC 
ATGTTCTGGT GGGCCTCTGG ACTGCTATGG AAGGGCTACA GGAAACTGCT GGGGCCAAAA 
GACCTCTGGT CACTTGAGAG AGAAAACTCT TCAGAAGAAC TTGTTTCCCA GCTGGAAAGA 
GAATGGAGGA GGAACTTCAG TGAGCTGCCG GGGCACAAAG GGCACAGTGG TATGGGGACC 
CCCGAGACAG AGGCCTTCCT GCAGCCAGAG AGGAGCCAGC GGGGCCCGCT GCTCAGGGCT 
ATCTGGCGTG TGTTCCGGTC CACTTTCCTG CTGGGGACCC TCAGCCTGGT CATTAGCGAT 
GCCTTCAGGT TTGCTGTTCC CAAGCTCCTC AGTCTGTTTC TGGAGTTCAT GGGCGACCTC 
GAGTCCTCGG CTTGGACGGG CTGGCTCCTG GCTGTGCTGA TGTTCTTGTC GGCCTGCCTA 
CAGACACTGT TTGAACAGCA GTACATGTAC AGAGTCAAGG TCCTGCAGAT GAGGCTGCGA 
ACAGCCATCA CTGGCCTGGT GTACAGAAAG GTCCTGGTCC TGTCCAGTGG TTCCAGAAAG 
TCCAGTGCAG CAGGGGACGT GGTCAACCTG GTGTCAGTGG ACGTACAGCG GCTGGTCGAG 
AGCATCCTCC ACCTCAACGG GCTGTGGCTG CTCTTCCTGT GGATCATTGT GTGCTTTGTC 
TACCTGTGGC AGCTCCTTGG GCCCTCTGCC CTCACAGCCG TTGCTGTCTT CCTGAGCCTT 
CTCCCCCTGA ACTTCTTCAT TACCAAGAAG AGGAGCTTCC ATCAGGAAGA ACAGATGAGG 
CAGAAGGCCT CCCGAGCACG GCTCACCAGC TCCATGCTCA GAACTGTGAG AACCATCAAG 
TCCCACGGCT GGGAGTGTGC CTTCCTGGAG CGACTCCTGC ATATCCGGGG CCAGGAGCTA 
GGTGCCCTGA AGACCTCCGC CTTCCTCTTC TCTGTGTCTC TCGTGTCCTT CCAAGTGTCT 
ACATTTCTGG TGGCGCTGGT TGTGTTTGCT GTCCACACCC TGGTGGCAGA GGACAACGCC 
ATGGATGCGG AGAAGGCGTT TGTGACGCTC ACGGTGCTCA GCATCCTTAA CAAAGCCCAG 
GCCTTCCTCC CCTTCTCTGT GCACTGCCTC GTTCAGGCTC GGGTGTCCTT TGACCGCCTA 
GCTGCTTTCC TGTGCCTGGA AGAAGTAGAC CCCAATGGCA TGGTCTTGAG TCCCTCCAGA 
TGCTCCTCGA AGGATCGAAT TTCTATACAC AATGGCACCT TCGCTTGGTC CCAGGAGAGC 
CCGCCCTGCC TGCACGGGAT CAACCTCACC GTGCCCCAGG GCTGTCTGCT GGCTGTTGTG 
GGTCCAGTGG GGGCTGGAAA GTCCTCCCTG CTGTCTGCCC TGCTTGGGGA GCTGTTGAAG 
GTAGAAGGGT CTGTGAGCAT TGAGGGTTCC GTGGCCTACG TGCCTCAGGA GGCTTGGGTC 
CAGAATACCT CTGTGGTGGA GAATGTGTGC TTCAGGCAGG AGCTGGATCT GCCATGGTTG 
CAGGAAGTTC TAGAAGCCTG TGCCTTGGGG TCTGATGTGG CCAGCTTCCC TGCAGGAGTT 
CACACCCCAG TAGGGGAGCA GGGCATGAAT CTTTCTGGGG GCCAGAAGCA GCGGCTGAGC 
TTGGCTCGGG CTGTGTACAG AAGGGCTGCT GTGTACCTGA TGGATGACCC CCTAGCAGCC 
CTGGATGCGC ATGTCAGCCA GGAAGTCTTC AAACAGGTCA TTGGCCCCAG TGGACTTCTC 
CAAGGTACGA CTCGGATCCT TGTAACACAC ACGCTGCATG TCCTGCCCCA AGCTGACCAG 
ATCCTGGTGC TGGCCAATGG GACCATCGCA GAGATGGGCT CCTACCAAGA CCTTCTGCAT 
AGGAACGGAG CCCTGGTGGG TCTTCTGGAT GGAGCCAGAC AGCCTGCAGG CGAAGGAGAA 
GGAGAAGCAC ATGCTGCAGC CACCAGTGAT GACCTTGGAG GCTTTTCTGG AGGTGGGACG 
CCCACGCGCA GACCAGAGAG GCCCAGACCC AGTGACGCAG CCCCTGTGAA GGGCAGTACT 
TCAGAGGCAC AGATGGAGCC TTCTCTGGAT GACGTTGAGG TCACTGGACT GACAGCAGGA 
GAGGACAGTG TGCAGTATGG CCGGGTGAAG AGCGCCACAT ACCTGAGCTA CCTGCGGGCG 
GTGGGCACAC CGCTCTGCAC CTACACCCTG TTCCTCTTCC TCTGCCAGCA AGTGGCGTCC 
TTCTGCCAAG GCTACTGGCT GAGCCTCTGG GCCGACGACC CGGTCGTGGA TGGGAAGCAG 
ATGCATTCAG CCCTGCGTGG CTCCATCTTT GGACTCCTTG GCTGTCTGCA AGCCATCGGA 
CTGTTTGCCT CCATGGCTGC GGTGTTCCTG GGTGGAGCCC GAGCTTCATG CCTGCTTTTC 
CGGAGCCTCC TCTGGGACGT GGCTCGCTCT CCCATTGGCT TCTTTGAGCG CACACCAGTC 
GGGAACCTGC TGAACCGTTT TTCCAAGGAG ACGGACATAG TGGATGTGGA CATCCCAGAC 
AAGATGAGGA CCCTGCTGAC CTATGCCTTT GGACTCCTGG AGGTTGGCCT GGCAGTGTCG 
ATGGCCACAC CACTGGCTAT TGTGGCCATC CTACCTCTTA TGCTCCTTTA TGCTGGGTTT 
CAGAGCCTCT ACGTGGCCAC ATGTTGCCAG CTGAGACGCC TGGAGTCGGC CAGTTACTCC 
TCAGTGTGTT CCCATCTGGC TGAGACCTTC CAGGGCAGTC AGGTGGTCAG GGCCTTCCAG 
GCCCAGGGGC CCTTCACAGC TCAGCACGAT GCCCTCATGG ATGAGAACCA GAGGATCAGT 
TTCCCGAGGC TGGTGGCTGA CAGGTGGCTG GCTGCCAACC TGGAGCTCCT GGGGAATGGC 
CTGGTGTTTG TGGCCGCTAC ATGTGCTGTG CTGAGCAAGG CTCACCTGAG TGCTGGCCTC 
GCGGGCTTCT CGGTTTCTGC TGCCCTCCAG GTAACACAGA CTCTGCAGTG GGTGGTCCGC 
AGCTGGACAG ATCTGGAGAA CAGCATGGTG GCCGTGGAGC GAGTACAGGA CTACGTTCAC 
ACCCCCAAGG AGGCTCCCTG GAGGCTGCCC TCCTCTGCAG CCCAGCCTCT CTGGCCCTGT 
GGGGGACAGA TTGAGTTCCG AGACTTTGGG CTCAGACACC GACCAGAGCT GCCCATGGCT 
GTGCAGGGTG TGTCCCTGAA GATCCATGCA GGGGAGAAGG TGGGCATCGT GGGCAGGACA 
GGGGCCGGGA AGTCCTCCCT GACTTGGGGC CTGCTGCGGC TTCAGGAGGC CACTGAGGGT 
GGTATTTGGA TCGATGGGGT CCCCATCACC GACATGGGGC TGCACACACT GCGGTCCAGA 
ATCACCATCA TCCCTCAGGA CCCTGTCCTG TTCCCGGGCT CGCTGCGGAT GAACCTGGAC 
CTGCTTCAGG AGAACACAGA TGAGGGCATC TGGGCAGCGC TGGAGACGGT GCAGCTCAAG 
GCCTTCGTGA CCAGCCTGCC TGGCCAGCTG CAGTATGAGT GCTCAGGCCA GGGAGATGAC 
CTGAGTGTGG GTCAGAAGCA GCTCCTGTGT CTGGCACGTG CCCTTCTCCG GAAAACCCAG 
ATCCTCATCC TGGATGAAGC CACTGCCTCC GTGGACCCAG GGACGGAGAT ACAGATGCAG 
GCGGCCCTCG AGCGCTGGTT TGCACAGTGT ACAGTGCTGC TCATTGCTCA CCGCCTGCGC 
TCCGTGATGA ACTGCGCCAG ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Abcc6 ( XM_017589770.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017445259.1 Rattus norvegicus ATP binding cassette subfamily C member 6 (Abcc6), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa56865
Clone ID Related Accession (Same CDS sequence)	XM_017589770.1
Accession Version	XM_017589770.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3678bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	multidrug resistance-associated protein 6 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGACCC CCGAGACAGA GGCCTTCCTG CAGCCAGAGA GGAGCCAGCG GGGCCCGCTG 
CTCAGGGCTA TCTGGCGTGT GTTCCGGTCC ACTTTCCTGC TGGGGACCCT CAGCCTGGTC 
ATTAGCGATG CCTTCAGGTT TGCTGTTCCC AAGCTCCTCA GTCTGTTTCT GGAGTTCATG 
GGCGACCTCG AGTCCTCGGC TTGGACGGGC TGGCTCCTGG CTGTGCTGAT GTTCTTGTCG 
GCCTGCCTAC AGACACTGTT TGAACAGCAG TACATGTACA GAGTCAAGGT CCTGCAGATG 
AGGCTGCGAA CAGCCATCAC TGGCCTGGTG TACAGAAAGG TCCTGGTCCT GTCCAGTGGT 
TCCAGAAAGT CCAGTGCAGC AGGGGACGTG GTCAACCTGG TGTCAGTGGA CGTACAGCGG 
CTGGTCGAGA GCATCCTCCA CCTCAACGGG CTGTGGCTGC TCTTCCTGTG GATCATTGTG 
TGCTTTGTCT ACCTGTGGCA GCTCCTTGGG CCCTCTGCCC TCACAGCCGT TGCTGTCTTC 
CTGAGCCTTC TCCCCCTGAA CTTCTTCATT ACCAAGAAGA GGAGCTTCCA TCAGGAAGAA 
CAGATGAGGC AGAAGGCCTC CCGAGCACGG CTCACCAGCT CCATGCTCAG AACTGTGAGA 
ACCATCAAGT CCCACGGCTG GGAGTGTGCC TTCCTGGAGC GACTCCTGCA TATCCGGGGC 
CAGGAGCTAG GTGCCCTGAA GACCTCCGCC TTCCTCTTCT CTGTGTCTCT CGTGTCCTTC 
CAAGTGTCTA CATTTCTGGT GGCGCTGGTT GTGTTTGCTG TCCACACCCT GGTGGCAGAG 
GACAACGCCA TGGATGCGGA GAAGGCGTTT GTGACGCTCA CGGTGCTCAG CATCCTTAAC 
AAAGCCCAGG CCTTCCTCCC CTTCTCTGTG CACTGCCTCG TTCAGGCTCG GGTGTCCTTT 
GACCGCCTAG CTGCTTTCCT GTGCCTGGAA GAAGTAGACC CCAATGGCAT GGTCTTGAGT 
CCCTCCAGAT GCTCCTCGAA GGATCGAATT TCTATACACA ATGGCACCTT CGCTTGGTCC 
CAGGAGAGCC CGCCCTGCCT GCACGGGATC AACCTCACCG TGCCCCAGGG CTGTCTGCTG 
GCTGTTGTGG GTCCAGTGGG GGCTGGAAAG TCCTCCCTGC TGTCTGCCCT GCTTGGGGAG 
CTGTTGAAGG TAGAAGGGTC TGTGAGCATT GAGGGTTCCG TGGCCTACGT GCCTCAGGAG 
GCTTGGGTCC AGAATACCTC TGTGGTGGAG AATGTGTGCT TCAGGCAGGA GCTGGATCTG 
CCATGGTTGC AGGAAGTTCT AGAAGCCTGT GCCTTGGGGT CTGATGTGGC CAGCTTCCCT 
GCAGGAGTTC ACACCCCAGT AGGGGAGCAG GGCATGAATC TTTCTGGGGG CCAGAAGCAG 
CGGCTGAGCT TGGCTCGGGC TGTGTACAGA AGGGCTGCTG TGTACCTGAT GGATGACCCC 
CTAGCAGCCC TGGATGCGCA TGTCAGCCAG GAAGTCTTCA AACAGGTCAT TGGCCCCAGT 
GGACTTCTCC AAGGTACGAC TCGGATCCTT GTAACACACA CGCTGCATGT CCTGCCCCAA 
GCTGACCAGA TCCTGGTGCT GGCCAATGGG ACCATCGCAG AGATGGGCTC CTACCAAGAC 
CTTCTGCATA GGAACGGAGC CCTGGTGGGT CTTCTGGATG GAGCCAGACA GCCTGCAGGC 
GAAGGAGAAG GAGAAGCACA TGCTGCAGCC ACCAGTGATG ACCTTGGAGG CTTTTCTGGA 
GGTGGGACGC CCACGCGCAG ACCAGAGAGG CCCAGACCCA GTGACGCAGC CCCTGTGAAG 
GGCAGTACTT CAGAGGCACA GATGGAGCCT TCTCTGGATG ACGTTGAGGT CACTGGACTG 
ACAGCAGGAG AGGACAGTGT GCAGTATGGC CGGGTGAAGA GCGCCACATA CCTGAGCTAC 
CTGCGGGCGG TGGGCACACC GCTCTGCACC TACACCCTGT TCCTCTTCCT CTGCCAGCAA 
GTGGCGTCCT TCTGCCAAGG CTACTGGCTG AGCCTCTGGG CCGACGACCC GGTCGTGGAT 
GGGAAGCAGA TGCATTCAGC CCTGCGTGGC TCCATCTTTG GACTCCTTGG CTGTCTGCAA 
GCCATCGGAC TGTTTGCCTC CATGGCTGCG GTGTTCCTGG GTGGAGCCCG AGCTTCATGC 
CTGCTTTTCC GGAGCCTCCT CTGGGACGTG GCTCGCTCTC CCATTGGCTT CTTTGAGCGC 
ACACCAGTCG GGAACCTGCT GAACCGTTTT TCCAAGGAGA CGGACATAGT GGATGTGGAC 
ATCCCAGACA AGATGAGGAC CCTGCTGACC TATGCCTTTG GACTCCTGGA GGTTGGCCTG 
GCAGTGTCGA TGGCCACACC ACTGGCTATT GTGGCCATCC TACCTCTTAT GCTCCTTTAT 
GCTGGGTTTC AGAGCCTCTA CGTGGCCACA TGTTGCCAGC TGAGACGCCT GGAGTCGGCC 
AGTTACTCCT CAGTGTGTTC CCATCTGGCT GAGACCTTCC AGGGCAGTCA GGTGGTCAGG 
GCCTTCCAGG CCCAGGGGCC CTTCACAGCT CAGCACGATG CCCTCATGGA TGAGAACCAG 
AGGATCAGTT TCCCGAGGCT GGTGGCTGAC AGGTGGCTGG CTGCCAACCT GGAGCTCCTG 
GGGAATGGCC TGGTGTTTGT GGCCGCTACA TGTGCTGTGC TGAGCAAGGC TCACCTGAGT 
GCTGGCCTCG CGGGCTTCTC GGTTTCTGCT GCCCTCCAGG TAACACAGAC TCTGCAGTGG 
GTGGTCCGCA GCTGGACAGA TCTGGAGAAC AGCATGGTGG CCGTGGAGCG AGTACAGGAC 
TACGTTCACA CCCCCAAGGA GGCTCCCTGG AGGCTGCCCT CCTCTGCAGC CCAGCCTCTC 
TGGCCCTGTG GGGGACAGAT TGAGTTCCGA GACTTTGGGC TCAGACACCG ACCAGAGCTG 
CCCATGGCTG TGCAGGGTGT GTCCCTGAAG ATCCATGCAG GGGAGAAGGT GGGCATCGTG 
GGCAGGACAG GGGCCGGGAA GTCCTCCCTG ACTTGGGGCC TGCTGCGGCT TCAGGAGGCC 
ACTGAGGGTG GTATTTGGAT CGATGGGGTC CCCATCACCG ACATGGGGCT GCACACACTG 
CGGTCCAGAA TCACCATCAT CCCTCAGGAC CCTGTCCTGT TCCCGGGCTC GCTGCGGATG 
AACCTGGACC TGCTTCAGGA GAACACAGAT GAGGGCATCT GGGCAGCGCT GGAGACGGTG 
CAGCTCAAGG CCTTCGTGAC CAGCCTGCCT GGCCAGCTGC AGTATGAGTG CTCAGGCCAG 
GGAGATGACC TGAGTGTGGG TCAGAAGCAG CTCCTGTGTC TGGCACGTGC CCTTCTCCGG 
AAAACCCAGA TCCTCATCCT GGATGAAGCC ACTGCCTCCG TGGACCCAGG GACGGAGATA 
CAGATGCAGG CGGCCCTCGA GCGCTGGTTT GCACAGTGTA CAGTGCTGCT CATTGCTCAC 
CGCCTGCGCT CCGTGATGAA CTGCGCCAGG GTTCTAGTCA TGGATGAGGG GCAGGTGGCA 
GAGAGTGGCA GTCCAGCACA GCTGCTGGCC CAGAAAGGCC TGTTTTACAG GCTAGCCCAG 
GAGTCGGGCC TAGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017445259.1
CDS	422..4099
Translation	MGTPETEAFLQPERSQRGPLLRAIWRVFRSTFLLGTLSLVISDAFRFAVPKLLSLFLEFMGDLESSAWTGWLLAVLMFLSACLQTLFEQQYMYRVKVLQMRLRTAITGLVYRKVLVLSSGSRKSSAAGDVVNLVSVDVQRLVESILHLNGLWLLFLWIIVCFVYLWQLLGPSALTAVAVFLSLLPLNFFITKKRSFHQEEQMRQKASRARLTSSMLRTVRTIKSHGWECAFLERLLHIRGQELGALKTSAFLFSVSLVSFQVSTFLVALVVFAVHTLVAEDNAMDAEKAFVTLTVLSILNKAQAFLPFSVHCLVQARVSFDRLAAFLCLEEVDPNGMVLSPSRCSSKDRISIHNGTFAWSQESPPCLHGINLTVPQGCLLAVVGPVGAGKSSLLSALLGELLKVEGSVSIEGSVAYVPQEAWVQNTSVVENVCFRQELDLPWLQEVLEACALGSDVASFPAGVHTPVGEQGMNLSGGQKQRLSLARAVYRRAAVYLMDDPLAALDAHVSQEVFKQVIGPSGLLQGTTRILVTHTLHVLPQADQILVLANGTIAEMGSYQDLLHRNGALVGLLDGARQPAGEGEGEAHAAATSDDLGGFSGGGTPTRRPERPRPSDAAPVKGSTSEAQMEPSLDDVEVTGLTAGEDSVQYGRVKSATYLSYLRAVGTPLCTYTLFLFLCQQVASFCQGYWLSLWADDPVVDGKQMHSALRGSIFGLLGCLQAIGLFASMAAVFLGGARASCLLFRSLLWDVARSPIGFFERTPVGNLLNRFSKETDIVDVDIPDKMRTLLTYAFGLLEVGLAVSMATPLAIVAILPLMLLYAGFQSLYVATCCQLRRLESASYSSVCSHLAETFQGSQVVRAFQAQGPFTAQHDALMDENQRISFPRLVADRWLAANLELLGNGLVFVAATCAVLSKAHLSAGLAGFSVSAALQVTQTLQWVVRSWTDLENSMVAVERVQDYVHTPKEAPWRLPSSAAQPLWPCGGQIEFRDFGLRHRPELPMAVQGVSLKIHAGEKVGIVGRTGAGKSSLTWGLLRLQEATEGGIWIDGVPITDMGLHTLRSRITIIPQDPVLFPGSLRMNLDLLQENTDEGIWAALETVQLKAFVTSLPGQLQYECSGQGDDLSVGQKQLLCLARALLRKTQILILDEATASVDPGTEIQMQAALERWFAQCTVLLIAHRLRSVMNCARVLVMDEGQVAESGSPAQLLAQKGLFYRLAQESGLA

Target ORF information:

RefSeq Version	XM_017589770.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ATP binding cassette subfamily C member 6 (Abcc6), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017589770.1

ORF Insert Sequence:

ATGGGGACCC CCGAGACAGA GGCCTTCCTG CAGCCAGAGA GGAGCCAGCG GGGCCCGCTG 
CTCAGGGCTA TCTGGCGTGT GTTCCGGTCC ACTTTCCTGC TGGGGACCCT CAGCCTGGTC 
ATTAGCGATG CCTTCAGGTT TGCTGTTCCC AAGCTCCTCA GTCTGTTTCT GGAGTTCATG 
GGCGACCTCG AGTCCTCGGC TTGGACGGGC TGGCTCCTGG CTGTGCTGAT GTTCTTGTCG 
GCCTGCCTAC AGACACTGTT TGAACAGCAG TACATGTACA GAGTCAAGGT CCTGCAGATG 
AGGCTGCGAA CAGCCATCAC TGGCCTGGTG TACAGAAAGG TCCTGGTCCT GTCCAGTGGT 
TCCAGAAAGT CCAGTGCAGC AGGGGACGTG GTCAACCTGG TGTCAGTGGA CGTACAGCGG 
CTGGTCGAGA GCATCCTCCA CCTCAACGGG CTGTGGCTGC TCTTCCTGTG GATCATTGTG 
TGCTTTGTCT ACCTGTGGCA GCTCCTTGGG CCCTCTGCCC TCACAGCCGT TGCTGTCTTC 
CTGAGCCTTC TCCCCCTGAA CTTCTTCATT ACCAAGAAGA GGAGCTTCCA TCAGGAAGAA 
CAGATGAGGC AGAAGGCCTC CCGAGCACGG CTCACCAGCT CCATGCTCAG AACTGTGAGA 
ACCATCAAGT CCCACGGCTG GGAGTGTGCC TTCCTGGAGC GACTCCTGCA TATCCGGGGC 
CAGGAGCTAG GTGCCCTGAA GACCTCCGCC TTCCTCTTCT CTGTGTCTCT CGTGTCCTTC 
CAAGTGTCTA CATTTCTGGT GGCGCTGGTT GTGTTTGCTG TCCACACCCT GGTGGCAGAG 
GACAACGCCA TGGATGCGGA GAAGGCGTTT GTGACGCTCA CGGTGCTCAG CATCCTTAAC 
AAAGCCCAGG CCTTCCTCCC CTTCTCTGTG CACTGCCTCG TTCAGGCTCG GGTGTCCTTT 
GACCGCCTAG CTGCTTTCCT GTGCCTGGAA GAAGTAGACC CCAATGGCAT GGTCTTGAGT 
CCCTCCAGAT GCTCCTCGAA GGATCGAATT TCTATACACA ATGGCACCTT CGCTTGGTCC 
CAGGAGAGCC CGCCCTGCCT GCACGGGATC AACCTCACCG TGCCCCAGGG CTGTCTGCTG 
GCTGTTGTGG GTCCAGTGGG GGCTGGAAAG TCCTCCCTGC TGTCTGCCCT GCTTGGGGAG 
CTGTTGAAGG TAGAAGGGTC TGTGAGCATT GAGGGTTCCG TGGCCTACGT GCCTCAGGAG 
GCTTGGGTCC AGAATACCTC TGTGGTGGAG AATGTGTGCT TCAGGCAGGA GCTGGATCTG 
CCATGGTTGC AGGAAGTTCT AGAAGCCTGT GCCTTGGGGT CTGATGTGGC CAGCTTCCCT 
GCAGGAGTTC ACACCCCAGT AGGGGAGCAG GGCATGAATC TTTCTGGGGG CCAGAAGCAG 
CGGCTGAGCT TGGCTCGGGC TGTGTACAGA AGGGCTGCTG TGTACCTGAT GGATGACCCC 
CTAGCAGCCC TGGATGCGCA TGTCAGCCAG GAAGTCTTCA AACAGGTCAT TGGCCCCAGT 
GGACTTCTCC AAGGTACGAC TCGGATCCTT GTAACACACA CGCTGCATGT CCTGCCCCAA 
GCTGACCAGA TCCTGGTGCT GGCCAATGGG ACCATCGCAG AGATGGGCTC CTACCAAGAC 
CTTCTGCATA GGAACGGAGC CCTGGTGGGT CTTCTGGATG GAGCCAGACA GCCTGCAGGC 
GAAGGAGAAG GAGAAGCACA TGCTGCAGCC ACCAGTGATG ACCTTGGAGG CTTTTCTGGA 
GGTGGGACGC CCACGCGCAG ACCAGAGAGG CCCAGACCCA GTGACGCAGC CCCTGTGAAG 
GGCAGTACTT CAGAGGCACA GATGGAGCCT TCTCTGGATG ACGTTGAGGT CACTGGACTG 
ACAGCAGGAG AGGACAGTGT GCAGTATGGC CGGGTGAAGA GCGCCACATA CCTGAGCTAC 
CTGCGGGCGG TGGGCACACC GCTCTGCACC TACACCCTGT TCCTCTTCCT CTGCCAGCAA 
GTGGCGTCCT TCTGCCAAGG CTACTGGCTG AGCCTCTGGG CCGACGACCC GGTCGTGGAT 
GGGAAGCAGA TGCATTCAGC CCTGCGTGGC TCCATCTTTG GACTCCTTGG CTGTCTGCAA 
GCCATCGGAC TGTTTGCCTC CATGGCTGCG GTGTTCCTGG GTGGAGCCCG AGCTTCATGC 
CTGCTTTTCC GGAGCCTCCT CTGGGACGTG GCTCGCTCTC CCATTGGCTT CTTTGAGCGC 
ACACCAGTCG GGAACCTGCT GAACCGTTTT TCCAAGGAGA CGGACATAGT GGATGTGGAC 
ATCCCAGACA AGATGAGGAC CCTGCTGACC TATGCCTTTG GACTCCTGGA GGTTGGCCTG 
GCAGTGTCGA TGGCCACACC ACTGGCTATT GTGGCCATCC TACCTCTTAT GCTCCTTTAT 
GCTGGGTTTC AGAGCCTCTA CGTGGCCACA TGTTGCCAGC TGAGACGCCT GGAGTCGGCC 
AGTTACTCCT CAGTGTGTTC CCATCTGGCT GAGACCTTCC AGGGCAGTCA GGTGGTCAGG 
GCCTTCCAGG CCCAGGGGCC CTTCACAGCT CAGCACGATG CCCTCATGGA TGAGAACCAG 
AGGATCAGTT TCCCGAGGCT GGTGGCTGAC AGGTGGCTGG CTGCCAACCT GGAGCTCCTG 
GGGAATGGCC TGGTGTTTGT GGCCGCTACA TGTGCTGTGC TGAGCAAGGC TCACCTGAGT 
GCTGGCCTCG CGGGCTTCTC GGTTTCTGCT GCCCTCCAGG TAACACAGAC TCTGCAGTGG 
GTGGTCCGCA GCTGGACAGA TCTGGAGAAC AGCATGGTGG CCGTGGAGCG AGTACAGGAC 
TACGTTCACA CCCCCAAGGA GGCTCCCTGG AGGCTGCCCT CCTCTGCAGC CCAGCCTCTC 
TGGCCCTGTG GGGGACAGAT TGAGTTCCGA GACTTTGGGC TCAGACACCG ACCAGAGCTG 
CCCATGGCTG TGCAGGGTGT GTCCCTGAAG ATCCATGCAG GGGAGAAGGT GGGCATCGTG 
GGCAGGACAG GGGCCGGGAA GTCCTCCCTG ACTTGGGGCC TGCTGCGGCT TCAGGAGGCC 
ACTGAGGGTG GTATTTGGAT CGATGGGGTC CCCATCACCG ACATGGGGCT GCACACACTG 
CGGTCCAGAA TCACCATCAT CCCTCAGGAC CCTGTCCTGT TCCCGGGCTC GCTGCGGATG 
AACCTGGACC TGCTTCAGGA GAACACAGAT GAGGGCATCT GGGCAGCGCT GGAGACGGTG 
CAGCTCAAGG CCTTCGTGAC CAGCCTGCCT GGCCAGCTGC AGTATGAGTG CTCAGGCCAG 
GGAGATGACC TGAGTGTGGG TCAGAAGCAG CTCCTGTGTC TGGCACGTGC CCTTCTCCGG 
AAAACCCAGA TCCTCATCCT GGATGAAGCC ACTGCCTCCG TGGACCCAGG GACGGAGATA 
CAGATGCAGG CGGCCCTCGA GCGCTGGTTT GCACAGTGTA CAGTGCTGCT CATTGCTCAC 
CGCCTGCGCT CCGTGATGAA CTGCGCCAGG GTTCTAGTCA TGGATGAGGG GCAGGTGGCA 
GAGAGTGGCA GTCCAGCACA GCTGCTGGCC CAGAAAGGCC TGTTTTACAG GCTAGCCCAG 
GAGTCGGGCC TAGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Abcc6 ( NM_031013.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_112275.1 Rattus norvegicus ATP binding cassette subfamily C member 6 (Abcc6), mRNA.

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CloneID	ORa07381
Clone ID Related Accession (Same CDS sequence)	NM_031013.1
Accession Version	NM_031013.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4509bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Rattus norvegicus(Norway rat)
Product	multidrug resistance-associated protein 6
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U73038.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U73038.1, AB010466.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGAACGGAG AGCACTCAAT GGCCACGCCT GGAGAGTCCT GCGCAGGCCT GAGGGTCTGG 
AACCAGACAG AACAGGAGCC TGTGGCCTAT CACTTGCTCA ACCTGTGCTT CCTGCGAGCC 
GCCGGGAGCT GGGTGCCCCC CATGTACCTC TGGGTCCTTG GCCCCATCTA CCTCCTCTAC 
ATCCATCGCC ATGGCTGCTG CTACCTCCGG ATGTCCCGCC TCTTCAAAAT CAAAATGGTG 
CTCGGCTTTG CCCTCATCCT TCTCTACACC TTCAACGCGG CCGTGCCTCT CTGGAGGATC 
CACCGGGGCA TGCCCCAGGC CCCAGAGCTT CTCATTCACC CTACCGTGTG GCTCACCACC 
ATGAGCTTCG CCACCTTCCT GATCCACATG GAGAGAAAGA AGGGGGTCCG TGCATCTGGG 
TTGTTGTTCG GGTACTGGCT GCTCTGCTGC CTCGTGCCAG CCATCGACAC TGTCCAGCAG 
GCCTCCGCAG GGAGCTTCCG CCAGGAGCCC CTCCACCACC TGGCCACCTA CCTGTGCTTG 
TCCCTGGTGG TGGCAGAGCT GGTGCTGTCT TGTCTGGTAG ACCAGCCACC CTTCTTCTCG 
GAAGACTCCA AGCCATTGAA TCCATGTCCA GAGGCCGAGG CCTCTTTTCC CTCCAAGGCC 
ATGTTCTGGT GGGCCTCTGG ACTGCTATGG AAGGGCTACA GGAAACTGCT GGGGCCAAAA 
GACCTCTGGT CACTTGAGAG AGAAAACTCT TCAGAAGAAC TTGTTTCCCA GCTGGAAAGA 
GAATGGAGGA GGAACTTCAG TGAGCTGCCG GGGCACAAAG GGCACAGTGG TATGGGGACC 
CCCGAGACAG AGGCCTTCCT GCAGCCAGAG AGGAGCCAGC GGGGCCCGCT GCTCAGGGCT 
ATCTGGCGTG TGTTCCGGTC CACTTTCCTG CTGGGGACCC TCAGCCTGGT CATTAGCGAT 
GCCTTCAGGT TTGCTGTTCC CAAGCTCCTC AGTCTGTTTC TGGAGTTCAT GGGCGACCTC 
GAGTCCTCGG CTTGGACGGG CTGGCTCCTG GCTGTGCTGA TGTTCTTGTC GGCCTGCCTA 
CAGACACTGT TTGAACAGCA GTACATGTAC AGAGTCAAGG TCCTGCAGAT GAGGCTGCGA 
ACAGCCATCA CTGGCCTGGT GTACAGAAAG GTCCTGGTCC TGTCCAGTGG TTCCAGAAAG 
TCCAGTGCAG CAGGGGACGT GGTCAACCTG GTGTCAGTGG ACGTACAGCG GCTGGTCGAG 
AGCATCCTCC ACCTCAACGG GCTGTGGCTG CTCTTCCTGT GGATCATTGT GTGCTTTGTC 
TACCTGTGGC AGCTCCTTGG GCCCTCTGCC CTCACAGCCG TTGCTGTCTT CCTGAGCCTT 
CTCCCCCTGA ACTTCTTCAT TACCAAGAAG AGGAGCTTCC ATCAGGAAGA ACAGATGAGG 
CAGAAGGCCT CCCGAGCACG GCTCACCAGC TCCATGCTCA GAACTGTGAG AACCATCAAG 
TCCCACGGCT GGGAGTGTGC CTTCCTGGAG CGACTCCTGC ATATCCGGGG CCAGGAGCTA 
GGTGCCCTGA AGACCTCCGC CTTCCTCTTC TCTGTGTCTC TCGTGTCCTT CCAAGTGTCT 
ACATTTCTGG TGGCGCTGGT TGTGTTTGCT GTCCACACCC TGGTGGCAGA GGACAACGCC 
ATGGATGCGG AGAAGGCGTT TGTGACGCTC ACGGTGCTCA GCATCCTTAA CAAAGCCCAG 
GCCTTCCTCC CCTTCTCTGT GCACTGCCTC GTTCAGGCTC GGGTGTCCTT TGACCGCCTA 
GCTGCTTTCC TGTGCCTGGA AGAAGTAGAC CCCAATGGCA TGGTCTTGAG TCCCTCCAGA 
TGCTCCTCGA AGGATCGAAT TTCTATACAC AATGGCACCT TCGCTTGGTC CCAGGAGAGC 
CCGCCCTGCC TGCACGGGAT CAACCTCACC GTGCCCCAGG GCTGTCTGCT GGCTGTTGTG 
GGTCCAGTGG GGGCTGGAAA GTCCTCCCTG CTGTCTGCCC TGCTTGGGGA GCTGTTGAAG 
GTAGAAGGGT CTGTGAGCAT TGAGGGTTCC GTGGCCTACG TGCCTCAGGA GGCTTGGGTC 
CAGAATACCT CTGTGGTGGA GAATGTGTGC TTCAGGCAGG AGCTGGATCT GCCATGGTTG 
CAGGAAGTTC TAGAAGCCTG TGCCTTGGGG TCTGATGTGG CCAGCTTCCC TGCAGGAGTT 
CACACCCCAG TAGGGGAGCA GGGCATGAAT CTTTCTGGGG GCCAGAAGCA GCGGCTGAGC 
TTGGCTCGGG CTGTGTACAG AAGGGCTGCT GTGTACCTGA TGGATGACCC CCTAGCAGCC 
CTGGATGCGC ATGTCAGCCA GGAAGTCTTC AAACAGGTCA TTGGCCCCAG TGGACTTCTC 
CAAGGTACGA CTCGGATCCT TGTAACACAC ACGCTGCATG TCCTGCCCCA AGCTGACCAG 
ATCCTGGTGC TGGCCAATGG GACCATCGCA GAGATGGGCT CCTACCAAGA CCTTCTGCAT 
AGGAACGGAG CCCTGGTGGG TCTTCTGGAT GGAGCCAGAC AGCCTGCAGG CGAAGGAGAA 
GGAGAAGCAC ATGCTGCAGC CACCAGTGAT GACCTTGGAG GCTTTTCTGG AGGTGGGACG 
CCCACGCGCA GACCAGAGAG GCCCAGACCC AGTGACGCAG CCCCTGTGAA GGGCAGTACT 
TCAGAGGCAC AGATGGAGCC TTCTCTGGAT GACGTTGAGG TCACTGGACT GACAGCAGGA 
GAGGACAGTG TGCAGTATGG CCGGGTGAAG AGCGCCACAT ACCTGAGCTA CCTGCGGGCG 
GTGGGCACAC CGCTCTGCAC CTACACCCTG TTCCTCTTCC TCTGCCAGCA AGTGGCGTCC 
TTCTGCCAAG GCTACTGGCT GAGCCTCTGG GCCGACGACC CGGTCGTGGA TGGGAAGCAG 
ATGCATTCAG CCCTGCGTGG CTCCATCTTT GGACTCCTTG GCTGTCTGCA AGCCATCGGA 
CTGTTTGCCT CCATGGCTGC GGTGTTCCTG GGTGGAGCCC GAGCTTCATG CCTGCTTTTC 
CGGAGCCTCC TCTGGGACGT GGCTCGCTCT CCCATTGGCT TCTTTGAGCG CACACCAGTC 
GGGAACCTGC TGAACCGTTT TTCCAAGGAG ACGGACATAG TGGATGTGGA CATCCCAGAC 
AAGATGAGGA CCCTGCTGAC CTATGCCTTT GGACTCCTGG AGGTTGGCCT GGCAGTGTCG 
ATGGCCACAC CACTGGCTAT TGTGGCCATC CTACCTCTTA TGCTCCTTTA TGCTGGGTTT 
CAGAGCCTCT ACGTGGCCAC ATGTTGCCAG CTGAGACGCC TGGAGTCGGC CAGTTACTCC 
TCAGTGTGTT CCCATCTGGC TGAGACCTTC CAGGGCAGTC AGGTGGTCAG GGCCTTCCAG 
GCCCAGGGGC CCTTCACAGC TCAGCACGAT GCCCTCATGG ATGAGAACCA GAGGATCAGT 
TTCCCGAGGC TGGTGGCTGA CAGGTGGCTG GCTGCCAACC TGGAGCTCCT GGGGAATGGC 
CTGGTGTTTG TGGCCGCTAC ATGTGCTGTG CTGAGCAAGG CTCACCTGAG TGCTGGCCTC 
GCGGGCTTCT CGGTTTCTGC TGCCCTCCAG GTAACACAGA CTCTGCAGTG GGTGGTCCGC 
AGCTGGACAG ATCTGGAGAA CAGCATGGTG GCCGTGGAGC GAGTACAGGA CTACGTTCAC 
ACCCCCAAGG AGGCTCCCTG GAGGCTGCCC TCCTCTGCAG CCCAGCCTCT CTGGCCCTGT 
GGGGGACAGA TTGAGTTCCG AGACTTTGGG CTCAGACACC GACCAGAGCT GCCCATGGCT 
GTGCAGGGTG TGTCCCTGAA GATCCATGCA GGGGAGAAGG TGGGCATCGT GGGCAGGACA 
GGGGCCGGGA AGTCCTCCCT GACTTGGGGC CTGCTGCGGC TTCAGGAGGC CACTGAGGGT 
GGTATTTGGA TCGATGGGGT CCCCATCACC GACATGGGGC TGCACACACT GCGGTCCAGA 
ATCACCATCA TCCCTCAGGA CCCTGTCCTG TTCCCGGGCT CGCTGCGGAT GAACCTGGAC 
CTGCTTCAGG AGAACACAGA TGAGGGCATC TGGGCAGCGC TGGAGACGGT GCAGCTCAAG 
GCCTTCGTGA CCAGCCTGCC TGGCCAGCTG CAGTATGAGT GCTCAGGCCA GGGAGATGAC 
CTGAGTGTGG GTCAGAAGCA GCTCCTGTGT CTGGCACGTG CCCTTCTCCG GAAAACCCAG 
ATCCTCATCC TGGATGAAGC CACTGCCTCC GTGGACCCAG GGACGGAGAT ACAGATGCAG 
GCGGCCCTCG AGCGCTGGTT TGCACAGTGT ACAGTGCTGC TCATTGCTCA CCGCCTGCGC 
TCCGTGATGA ACTGCGCCAG GGTTCTAGTC ATGGATGAGG GGCAGGTGGC AGAGAGTGGC 
AGTCCAGCAC AGCTGCTGGC CCAGAAAGGC CTGTTTTACA GGCTAGCCCA GGAGTCGGGC 
CTAGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_112275.1
CDS	72..4580
Translation	MNGEHSMATPGESCAGLRVWNQTEQEPVAYHLLNLCFLRAAGSWVPPMYLWVLGPIYLLYIHRHGCCYLRMSRLFKIKMVLGFALILLYTFNAAVPLWRIHRGMPQAPELLIHPTVWLTTMSFATFLIHMERKKGVRASGLLFGYWLLCCLVPAIDTVQQASAGSFRQEPLHHLATYLCLSLVVAELVLSCLVDQPPFFSEDSKPLNPCPEAEASFPSKAMFWWASGLLWKGYRKLLGPKDLWSLERENSSEELVSQLEREWRRNFSELPGHKGHSGMGTPETEAFLQPERSQRGPLLRAIWRVFRSTFLLGTLSLVISDAFRFAVPKLLSLFLEFMGDLESSAWTGWLLAVLMFLSACLQTLFEQQYMYRVKVLQMRLRTAITGLVYRKVLVLSSGSRKSSAAGDVVNLVSVDVQRLVESILHLNGLWLLFLWIIVCFVYLWQLLGPSALTAVAVFLSLLPLNFFITKKRSFHQEEQMRQKASRARLTSSMLRTVRTIKSHGWECAFLERLLHIRGQELGALKTSAFLFSVSLVSFQVSTFLVALVVFAVHTLVAEDNAMDAEKAFVTLTVLSILNKAQAFLPFSVHCLVQARVSFDRLAAFLCLEEVDPNGMVLSPSRCSSKDRISIHNGTFAWSQESPPCLHGINLTVPQGCLLAVVGPVGAGKSSLLSALLGELLKVEGSVSIEGSVAYVPQEAWVQNTSVVENVCFRQELDLPWLQEVLEACALGSDVASFPAGVHTPVGEQGMNLSGGQKQRLSLARAVYRRAAVYLMDDPLAALDAHVSQEVFKQVIGPSGLLQGTTRILVTHTLHVLPQADQILVLANGTIAEMGSYQDLLHRNGALVGLLDGARQPAGEGEGEAHAAATSDDLGGFSGGGTPTRRPERPRPSDAAPVKGSTSEAQMEPSLDDVEVTGLTAGEDSVQYGRVKSATYLSYLRAVGTPLCTYTLFLFLCQQVASFCQGYWLSLWADDPVVDGKQMHSALRGSIFGLLGCLQAIGLFASMAAVFLGGARASCLLFRSLLWDVARSPIGFFERTPVGNLLNRFSKETDIVDVDIPDKMRTLLTYAFGLLEVGLAVSMATPLAIVAILPLMLLYAGFQSLYVATCCQLRRLESASYSSVCSHLAETFQGSQVVRAFQAQGPFTAQHDALMDENQRISFPRLVADRWLAANLELLGNGLVFVAATCAVLSKAHLSAGLAGFSVSAALQVTQTLQWVVRSWTDLENSMVAVERVQDYVHTPKEAPWRLPSSAAQPLWPCGGQIEFRDFGLRHRPELPMAVQGVSLKIHAGEKVGIVGRTGAGKSSLTWGLLRLQEATEGGIWIDGVPITDMGLHTLRSRITIIPQDPVLFPGSLRMNLDLLQENTDEGIWAALETVQLKAFVTSLPGQLQYECSGQGDDLSVGQKQLLCLARALLRKTQILILDEATASVDPGTEIQMQAALERWFAQCTVLLIAHRLRSVMNCARVLVMDEGQVAESGSPAQLLAQKGLFYRLAQESGLA

Target ORF information:

RefSeq Version	NM_031013.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ATP binding cassette subfamily C member 6 (Abcc6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031013.1

ORF Insert Sequence:

ATGAACGGAG AGCACTCAAT GGCCACGCCT GGAGAGTCCT GCGCAGGCCT GAGGGTCTGG 
AACCAGACAG AACAGGAGCC TGTGGCCTAT CACTTGCTCA ACCTGTGCTT CCTGCGAGCC 
GCCGGGAGCT GGGTGCCCCC CATGTACCTC TGGGTCCTTG GCCCCATCTA CCTCCTCTAC 
ATCCATCGCC ATGGCTGCTG CTACCTCCGG ATGTCCCGCC TCTTCAAAAT CAAAATGGTG 
CTCGGCTTTG CCCTCATCCT TCTCTACACC TTCAACGCGG CCGTGCCTCT CTGGAGGATC 
CACCGGGGCA TGCCCCAGGC CCCAGAGCTT CTCATTCACC CTACCGTGTG GCTCACCACC 
ATGAGCTTCG CCACCTTCCT GATCCACATG GAGAGAAAGA AGGGGGTCCG TGCATCTGGG 
TTGTTGTTCG GGTACTGGCT GCTCTGCTGC CTCGTGCCAG CCATCGACAC TGTCCAGCAG 
GCCTCCGCAG GGAGCTTCCG CCAGGAGCCC CTCCACCACC TGGCCACCTA CCTGTGCTTG 
TCCCTGGTGG TGGCAGAGCT GGTGCTGTCT TGTCTGGTAG ACCAGCCACC CTTCTTCTCG 
GAAGACTCCA AGCCATTGAA TCCATGTCCA GAGGCCGAGG CCTCTTTTCC CTCCAAGGCC 
ATGTTCTGGT GGGCCTCTGG ACTGCTATGG AAGGGCTACA GGAAACTGCT GGGGCCAAAA 
GACCTCTGGT CACTTGAGAG AGAAAACTCT TCAGAAGAAC TTGTTTCCCA GCTGGAAAGA 
GAATGGAGGA GGAACTTCAG TGAGCTGCCG GGGCACAAAG GGCACAGTGG TATGGGGACC 
CCCGAGACAG AGGCCTTCCT GCAGCCAGAG AGGAGCCAGC GGGGCCCGCT GCTCAGGGCT 
ATCTGGCGTG TGTTCCGGTC CACTTTCCTG CTGGGGACCC TCAGCCTGGT CATTAGCGAT 
GCCTTCAGGT TTGCTGTTCC CAAGCTCCTC AGTCTGTTTC TGGAGTTCAT GGGCGACCTC 
GAGTCCTCGG CTTGGACGGG CTGGCTCCTG GCTGTGCTGA TGTTCTTGTC GGCCTGCCTA 
CAGACACTGT TTGAACAGCA GTACATGTAC AGAGTCAAGG TCCTGCAGAT GAGGCTGCGA 
ACAGCCATCA CTGGCCTGGT GTACAGAAAG GTCCTGGTCC TGTCCAGTGG TTCCAGAAAG 
TCCAGTGCAG CAGGGGACGT GGTCAACCTG GTGTCAGTGG ACGTACAGCG GCTGGTCGAG 
AGCATCCTCC ACCTCAACGG GCTGTGGCTG CTCTTCCTGT GGATCATTGT GTGCTTTGTC 
TACCTGTGGC AGCTCCTTGG GCCCTCTGCC CTCACAGCCG TTGCTGTCTT CCTGAGCCTT 
CTCCCCCTGA ACTTCTTCAT TACCAAGAAG AGGAGCTTCC ATCAGGAAGA ACAGATGAGG 
CAGAAGGCCT CCCGAGCACG GCTCACCAGC TCCATGCTCA GAACTGTGAG AACCATCAAG 
TCCCACGGCT GGGAGTGTGC CTTCCTGGAG CGACTCCTGC ATATCCGGGG CCAGGAGCTA 
GGTGCCCTGA AGACCTCCGC CTTCCTCTTC TCTGTGTCTC TCGTGTCCTT CCAAGTGTCT 
ACATTTCTGG TGGCGCTGGT TGTGTTTGCT GTCCACACCC TGGTGGCAGA GGACAACGCC 
ATGGATGCGG AGAAGGCGTT TGTGACGCTC ACGGTGCTCA GCATCCTTAA CAAAGCCCAG 
GCCTTCCTCC CCTTCTCTGT GCACTGCCTC GTTCAGGCTC GGGTGTCCTT TGACCGCCTA 
GCTGCTTTCC TGTGCCTGGA AGAAGTAGAC CCCAATGGCA TGGTCTTGAG TCCCTCCAGA 
TGCTCCTCGA AGGATCGAAT TTCTATACAC AATGGCACCT TCGCTTGGTC CCAGGAGAGC 
CCGCCCTGCC TGCACGGGAT CAACCTCACC GTGCCCCAGG GCTGTCTGCT GGCTGTTGTG 
GGTCCAGTGG GGGCTGGAAA GTCCTCCCTG CTGTCTGCCC TGCTTGGGGA GCTGTTGAAG 
GTAGAAGGGT CTGTGAGCAT TGAGGGTTCC GTGGCCTACG TGCCTCAGGA GGCTTGGGTC 
CAGAATACCT CTGTGGTGGA GAATGTGTGC TTCAGGCAGG AGCTGGATCT GCCATGGTTG 
CAGGAAGTTC TAGAAGCCTG TGCCTTGGGG TCTGATGTGG CCAGCTTCCC TGCAGGAGTT 
CACACCCCAG TAGGGGAGCA GGGCATGAAT CTTTCTGGGG GCCAGAAGCA GCGGCTGAGC 
TTGGCTCGGG CTGTGTACAG AAGGGCTGCT GTGTACCTGA TGGATGACCC CCTAGCAGCC 
CTGGATGCGC ATGTCAGCCA GGAAGTCTTC AAACAGGTCA TTGGCCCCAG TGGACTTCTC 
CAAGGTACGA CTCGGATCCT TGTAACACAC ACGCTGCATG TCCTGCCCCA AGCTGACCAG 
ATCCTGGTGC TGGCCAATGG GACCATCGCA GAGATGGGCT CCTACCAAGA CCTTCTGCAT 
AGGAACGGAG CCCTGGTGGG TCTTCTGGAT GGAGCCAGAC AGCCTGCAGG CGAAGGAGAA 
GGAGAAGCAC ATGCTGCAGC CACCAGTGAT GACCTTGGAG GCTTTTCTGG AGGTGGGACG 
CCCACGCGCA GACCAGAGAG GCCCAGACCC AGTGACGCAG CCCCTGTGAA GGGCAGTACT 
TCAGAGGCAC AGATGGAGCC TTCTCTGGAT GACGTTGAGG TCACTGGACT GACAGCAGGA 
GAGGACAGTG TGCAGTATGG CCGGGTGAAG AGCGCCACAT ACCTGAGCTA CCTGCGGGCG 
GTGGGCACAC CGCTCTGCAC CTACACCCTG TTCCTCTTCC TCTGCCAGCA AGTGGCGTCC 
TTCTGCCAAG GCTACTGGCT GAGCCTCTGG GCCGACGACC CGGTCGTGGA TGGGAAGCAG 
ATGCATTCAG CCCTGCGTGG CTCCATCTTT GGACTCCTTG GCTGTCTGCA AGCCATCGGA 
CTGTTTGCCT CCATGGCTGC GGTGTTCCTG GGTGGAGCCC GAGCTTCATG CCTGCTTTTC 
CGGAGCCTCC TCTGGGACGT GGCTCGCTCT CCCATTGGCT TCTTTGAGCG CACACCAGTC 
GGGAACCTGC TGAACCGTTT TTCCAAGGAG ACGGACATAG TGGATGTGGA CATCCCAGAC 
AAGATGAGGA CCCTGCTGAC CTATGCCTTT GGACTCCTGG AGGTTGGCCT GGCAGTGTCG 
ATGGCCACAC CACTGGCTAT TGTGGCCATC CTACCTCTTA TGCTCCTTTA TGCTGGGTTT 
CAGAGCCTCT ACGTGGCCAC ATGTTGCCAG CTGAGACGCC TGGAGTCGGC CAGTTACTCC 
TCAGTGTGTT CCCATCTGGC TGAGACCTTC CAGGGCAGTC AGGTGGTCAG GGCCTTCCAG 
GCCCAGGGGC CCTTCACAGC TCAGCACGAT GCCCTCATGG ATGAGAACCA GAGGATCAGT 
TTCCCGAGGC TGGTGGCTGA CAGGTGGCTG GCTGCCAACC TGGAGCTCCT GGGGAATGGC 
CTGGTGTTTG TGGCCGCTAC ATGTGCTGTG CTGAGCAAGG CTCACCTGAG TGCTGGCCTC 
GCGGGCTTCT CGGTTTCTGC TGCCCTCCAG GTAACACAGA CTCTGCAGTG GGTGGTCCGC 
AGCTGGACAG ATCTGGAGAA CAGCATGGTG GCCGTGGAGC GAGTACAGGA CTACGTTCAC 
ACCCCCAAGG AGGCTCCCTG GAGGCTGCCC TCCTCTGCAG CCCAGCCTCT CTGGCCCTGT 
GGGGGACAGA TTGAGTTCCG AGACTTTGGG CTCAGACACC GACCAGAGCT GCCCATGGCT 
GTGCAGGGTG TGTCCCTGAA GATCCATGCA GGGGAGAAGG TGGGCATCGT GGGCAGGACA 
GGGGCCGGGA AGTCCTCCCT GACTTGGGGC CTGCTGCGGC TTCAGGAGGC CACTGAGGGT 
GGTATTTGGA TCGATGGGGT CCCCATCACC GACATGGGGC TGCACACACT GCGGTCCAGA 
ATCACCATCA TCCCTCAGGA CCCTGTCCTG TTCCCGGGCT CGCTGCGGAT GAACCTGGAC 
CTGCTTCAGG AGAACACAGA TGAGGGCATC TGGGCAGCGC TGGAGACGGT GCAGCTCAAG 
GCCTTCGTGA CCAGCCTGCC TGGCCAGCTG CAGTATGAGT GCTCAGGCCA GGGAGATGAC 
CTGAGTGTGG GTCAGAAGCA GCTCCTGTGT CTGGCACGTG CCCTTCTCCG GAAAACCCAG 
ATCCTCATCC TGGATGAAGC CACTGCCTCC GTGGACCCAG GGACGGAGAT ACAGATGCAG 
GCGGCCCTCG AGCGCTGGTT TGCACAGTGT ACAGTGCTGC TCATTGCTCA CCGCCTGCGC 
TCCGTGATGA ACTGCGCCAG GGTTCTAGTC ATGGATGAGG GGCAGGTGGC AGAGAGTGGC 
AGTCCAGCAC AGCTGCTGGC CCAGAAAGGC CTGTTTTACA GGCTAGCCCA GGAGTCGGGC 
CTAGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Abcc6 ( XM_006229159.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006229221.1 Rattus norvegicus ATP binding cassette subfamily C member 6 (Abcc6), transcript variant X2, mRNA.

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CloneID	ORa22787
Clone ID Related Accession (Same CDS sequence)	XM_006229159.2 , XM_008759419.2
Accession Version	XM_006229159.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4200bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	multidrug resistance-associated protein 6 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 7, 2014 this sequence version replaced XM_006229159.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCCCAGG CCCCAGAGCT TCTCATTCAC CCTACCGTGT GGCTCACCAC CATGAGCTTC 
GCCACCTTCC TGATCCACAT GGAGAGAAAG AAGGGGGTCC GTGCATCTGG GTTGTTGTTC 
GGGTACTGGC TGCTCTGCTG CCTCGTGCCA GCCATCGACA CTGTCCAGCA GGCCTCCGCA 
GGGAGCTTCC GCCAGGAGCC CCTCCACCAC CTGGCCACCT ACCTGTGCTT GTCCCTGGTG 
GTGGCAGAGC TGGTGCTGTC TTGTCTGGTA GACCAGCCAC CCTTCTTCTC GGAAGACTCC 
AAGCCATTGA ATCCATGTCC AGAGGCCGAG GCCTCTTTTC CCTCCAAGGC CATGTTCTGG 
TGGGCCTCTG GACTGCTATG GAAGGGCTAC AGGAAACTGC TGGGGCCAAA AGACCTCTGG 
TCACTTGAGA GAGAAAACTC TTCAGAAGAA CTTGTTTCCC AGCTGGAAAG AGAATGGAGG 
AGGAACTTCA GTGAGCTGCC GGGGCACAAA GGGCACAGTG GTATGGGGAC CCCCGAGACA 
GAGGCCTTCC TGCAGCCAGA GAGGAGCCAG CGGGGCCCGC TGCTCAGGGC TATCTGGCGT 
GTGTTCCGGT CCACTTTCCT GCTGGGGACC CTCAGCCTGG TCATTAGCGA TGCCTTCAGG 
TTTGCTGTTC CCAAGCTCCT CAGTCTGTTT CTGGAGTTCA TGGGCGACCT CGAGTCCTCG 
GCTTGGACGG GCTGGCTCCT GGCTGTGCTG ATGTTCTTGT CGGCCTGCCT ACAGACACTG 
TTTGAACAGC AGTACATGTA CAGAGTCAAG GTCCTGCAGA TGAGGCTGCG AACAGCCATC 
ACTGGCCTGG TGTACAGAAA GGTCCTGGTC CTGTCCAGTG GTTCCAGAAA GTCCAGTGCA 
GCAGGGGACG TGGTCAACCT GGTGTCAGTG GACGTACAGC GGCTGGTCGA GAGCATCCTC 
CACCTCAACG GGCTGTGGCT GCTCTTCCTG TGGATCATTG TGTGCTTTGT CTACCTGTGG 
CAGCTCCTTG GGCCCTCTGC CCTCACAGCC GTTGCTGTCT TCCTGAGCCT TCTCCCCCTG 
AACTTCTTCA TTACCAAGAA GAGGAGCTTC CATCAGGAAG AACAGATGAG GCAGAAGGCC 
TCCCGAGCAC GGCTCACCAG CTCCATGCTC AGAACTGTGA GAACCATCAA GTCCCACGGC 
TGGGAGTGTG CCTTCCTGGA GCGACTCCTG CATATCCGGG GCCAGGAGCT AGGTGCCCTG 
AAGACCTCCG CCTTCCTCTT CTCTGTGTCT CTCGTGTCCT TCCAAGTGTC TACATTTCTG 
GTGGCGCTGG TTGTGTTTGC TGTCCACACC CTGGTGGCAG AGGACAACGC CATGGATGCG 
GAGAAGGCGT TTGTGACGCT CACGGTGCTC AGCATCCTTA ACAAAGCCCA GGCCTTCCTC 
CCCTTCTCTG TGCACTGCCT CGTTCAGGCT CGGGTGTCCT TTGACCGCCT AGCTGCTTTC 
CTGTGCCTGG AAGAAGTAGA CCCCAATGGC ATGGTCTTGA GTCCCTCCAG ATGCTCCTCG 
AAGGATCGAA TTTCTATACA CAATGGCACC TTCGCTTGGT CCCAGGAGAG CCCGCCCTGC 
CTGCACGGGA TCAACCTCAC CGTGCCCCAG GGCTGTCTGC TGGCTGTTGT GGGTCCAGTG 
GGGGCTGGAA AGTCCTCCCT GCTGTCTGCC CTGCTTGGGG AGCTGTTGAA GGTAGAAGGG 
TCTGTGAGCA TTGAGGGTTC CGTGGCCTAC GTGCCTCAGG AGGCTTGGGT CCAGAATACC 
TCTGTGGTGG AGAATGTGTG CTTCAGGCAG GAGCTGGATC TGCCATGGTT GCAGGAAGTT 
CTAGAAGCCT GTGCCTTGGG GTCTGATGTG GCCAGCTTCC CTGCAGGAGT TCACACCCCA 
GTAGGGGAGC AGGGCATGAA TCTTTCTGGG GGCCAGAAGC AGCGGCTGAG CTTGGCTCGG 
GCTGTGTACA GAAGGGCTGC TGTGTACCTG ATGGATGACC CCCTAGCAGC CCTGGATGCG 
CATGTCAGCC AGGAAGTCTT CAAACAGGTC ATTGGCCCCA GTGGACTTCT CCAAGGTACG 
ACTCGGATCC TTGTAACACA CACGCTGCAT GTCCTGCCCC AAGCTGACCA GATCCTGGTG 
CTGGCCAATG GGACCATCGC AGAGATGGGC TCCTACCAAG ACCTTCTGCA TAGGAACGGA 
GCCCTGGTGG GTCTTCTGGA TGGAGCCAGA CAGCCTGCAG GCGAAGGAGA AGGAGAAGCA 
CATGCTGCAG CCACCAGTGA TGACCTTGGA GGCTTTTCTG GAGGTGGGAC GCCCACGCGC 
AGACCAGAGA GGCCCAGACC CAGTGACGCA GCCCCTGTGA AGGGCAGTAC TTCAGAGGCA 
CAGATGGAGC CTTCTCTGGA TGACGTTGAG GTCACTGGAC TGACAGCAGG AGAGGACAGT 
GTGCAGTATG GCCGGGTGAA GAGCGCCACA TACCTGAGCT ACCTGCGGGC GGTGGGCACA 
CCGCTCTGCA CCTACACCCT GTTCCTCTTC CTCTGCCAGC AAGTGGCGTC CTTCTGCCAA 
GGCTACTGGC TGAGCCTCTG GGCCGACGAC CCGGTCGTGG ATGGGAAGCA GATGCATTCA 
GCCCTGCGTG GCTCCATCTT TGGACTCCTT GGCTGTCTGC AAGCCATCGG ACTGTTTGCC 
TCCATGGCTG CGGTGTTCCT GGGTGGAGCC CGAGCTTCAT GCCTGCTTTT CCGGAGCCTC 
CTCTGGGACG TGGCTCGCTC TCCCATTGGC TTCTTTGAGC GCACACCAGT CGGGAACCTG 
CTGAACCGTT TTTCCAAGGA GACGGACATA GTGGATGTGG ACATCCCAGA CAAGATGAGG 
ACCCTGCTGA CCTATGCCTT TGGACTCCTG GAGGTTGGCC TGGCAGTGTC GATGGCCACA 
CCACTGGCTA TTGTGGCCAT CCTACCTCTT ATGCTCCTTT ATGCTGGGTT TCAGAGCCTC 
TACGTGGCCA CATGTTGCCA GCTGAGACGC CTGGAGTCGG CCAGTTACTC CTCAGTGTGT 
TCCCATCTGG CTGAGACCTT CCAGGGCAGT CAGGTGGTCA GGGCCTTCCA GGCCCAGGGG 
CCCTTCACAG CTCAGCACGA TGCCCTCATG GATGAGAACC AGAGGATCAG TTTCCCGAGG 
CTGGTGGCTG ACAGGTGGCT GGCTGCCAAC CTGGAGCTCC TGGGGAATGG CCTGGTGTTT 
GTGGCCGCTA CATGTGCTGT GCTGAGCAAG GCTCACCTGA GTGCTGGCCT CGCGGGCTTC 
TCGGTTTCTG CTGCCCTCCA GGTAACACAG ACTCTGCAGT GGGTGGTCCG CAGCTGGACA 
GATCTGGAGA ACAGCATGGT GGCCGTGGAG CGAGTACAGG ACTACGTTCA CACCCCCAAG 
GAGGCTCCCT GGAGGCTGCC CTCCTCTGCA GCCCAGCCTC TCTGGCCCTG TGGGGGACAG 
ATTGAGTTCC GAGACTTTGG GCTCAGACAC CGACCAGAGC TGCCCATGGC TGTGCAGGGT 
GTGTCCCTGA AGATCCATGC AGGGGAGAAG GTGGGCATCG TGGGCAGGAC AGGGGCCGGG 
AAGTCCTCCC TGACTTGGGG CCTGCTGCGG CTTCAGGAGG CCACTGAGGG TGGTATTTGG 
ATCGATGGGG TCCCCATCAC CGACATGGGG CTGCACACAC TGCGGTCCAG AATCACCATC 
ATCCCTCAGG ACCCTGTCCT GTTCCCGGGC TCGCTGCGGA TGAACCTGGA CCTGCTTCAG 
GAGAACACAG ATGAGGGCAT CTGGGCAGCG CTGGAGACGG TGCAGCTCAA GGCCTTCGTG 
ACCAGCCTGC CTGGCCAGCT GCAGTATGAG TGCTCAGGCC AGGGAGATGA CCTGAGTGTG 
GGTCAGAAGC AGCTCCTGTG TCTGGCACGT GCCCTTCTCC GGAAAACCCA GATCCTCATC 
CTGGATGAAG CCACTGCCTC CGTGGACCCA GGGACGGAGA TACAGATGCA GGCGGCCCTC 
GAGCGCTGGT TTGCACAGTG TACAGTGCTG CTCATTGCTC ACCGCCTGCG CTCCGTGATG 
AACTGCGCCA GGGTTCTAGT CATGGATGAG GGGCAGGTGG CAGAGAGTGG CAGTCCAGCA 
CAGCTGCTGG CCCAGAAAGG CCTGTTTTAC AGGCTAGCCC AGGAGTCGGG CCTAGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006229221.1
CDS	298..4497
Translation	MPQAPELLIHPTVWLTTMSFATFLIHMERKKGVRASGLLFGYWLLCCLVPAIDTVQQASAGSFRQEPLHHLATYLCLSLVVAELVLSCLVDQPPFFSEDSKPLNPCPEAEASFPSKAMFWWASGLLWKGYRKLLGPKDLWSLERENSSEELVSQLEREWRRNFSELPGHKGHSGMGTPETEAFLQPERSQRGPLLRAIWRVFRSTFLLGTLSLVISDAFRFAVPKLLSLFLEFMGDLESSAWTGWLLAVLMFLSACLQTLFEQQYMYRVKVLQMRLRTAITGLVYRKVLVLSSGSRKSSAAGDVVNLVSVDVQRLVESILHLNGLWLLFLWIIVCFVYLWQLLGPSALTAVAVFLSLLPLNFFITKKRSFHQEEQMRQKASRARLTSSMLRTVRTIKSHGWECAFLERLLHIRGQELGALKTSAFLFSVSLVSFQVSTFLVALVVFAVHTLVAEDNAMDAEKAFVTLTVLSILNKAQAFLPFSVHCLVQARVSFDRLAAFLCLEEVDPNGMVLSPSRCSSKDRISIHNGTFAWSQESPPCLHGINLTVPQGCLLAVVGPVGAGKSSLLSALLGELLKVEGSVSIEGSVAYVPQEAWVQNTSVVENVCFRQELDLPWLQEVLEACALGSDVASFPAGVHTPVGEQGMNLSGGQKQRLSLARAVYRRAAVYLMDDPLAALDAHVSQEVFKQVIGPSGLLQGTTRILVTHTLHVLPQADQILVLANGTIAEMGSYQDLLHRNGALVGLLDGARQPAGEGEGEAHAAATSDDLGGFSGGGTPTRRPERPRPSDAAPVKGSTSEAQMEPSLDDVEVTGLTAGEDSVQYGRVKSATYLSYLRAVGTPLCTYTLFLFLCQQVASFCQGYWLSLWADDPVVDGKQMHSALRGSIFGLLGCLQAIGLFASMAAVFLGGARASCLLFRSLLWDVARSPIGFFERTPVGNLLNRFSKETDIVDVDIPDKMRTLLTYAFGLLEVGLAVSMATPLAIVAILPLMLLYAGFQSLYVATCCQLRRLESASYSSVCSHLAETFQGSQVVRAFQAQGPFTAQHDALMDENQRISFPRLVADRWLAANLELLGNGLVFVAATCAVLSKAHLSAGLAGFSVSAALQVTQTLQWVVRSWTDLENSMVAVERVQDYVHTPKEAPWRLPSSAAQPLWPCGGQIEFRDFGLRHRPELPMAVQGVSLKIHAGEKVGIVGRTGAGKSSLTWGLLRLQEATEGGIWIDGVPITDMGLHTLRSRITIIPQDPVLFPGSLRMNLDLLQENTDEGIWAALETVQLKAFVTSLPGQLQYECSGQGDDLSVGQKQLLCLARALLRKTQILILDEATASVDPGTEIQMQAALERWFAQCTVLLIAHRLRSVMNCARVLVMDEGQVAESGSPAQLLAQKGLFYRLAQESGLA

Target ORF information:

RefSeq Version	XM_006229159.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ATP binding cassette subfamily C member 6 (Abcc6), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006229159.2

ORF Insert Sequence:

ATGCCCCAGG CCCCAGAGCT TCTCATTCAC CCTACCGTGT GGCTCACCAC CATGAGCTTC 
GCCACCTTCC TGATCCACAT GGAGAGAAAG AAGGGGGTCC GTGCATCTGG GTTGTTGTTC 
GGGTACTGGC TGCTCTGCTG CCTCGTGCCA GCCATCGACA CTGTCCAGCA GGCCTCCGCA 
GGGAGCTTCC GCCAGGAGCC CCTCCACCAC CTGGCCACCT ACCTGTGCTT GTCCCTGGTG 
GTGGCAGAGC TGGTGCTGTC TTGTCTGGTA GACCAGCCAC CCTTCTTCTC GGAAGACTCC 
AAGCCATTGA ATCCATGTCC AGAGGCCGAG GCCTCTTTTC CCTCCAAGGC CATGTTCTGG 
TGGGCCTCTG GACTGCTATG GAAGGGCTAC AGGAAACTGC TGGGGCCAAA AGACCTCTGG 
TCACTTGAGA GAGAAAACTC TTCAGAAGAA CTTGTTTCCC AGCTGGAAAG AGAATGGAGG 
AGGAACTTCA GTGAGCTGCC GGGGCACAAA GGGCACAGTG GTATGGGGAC CCCCGAGACA 
GAGGCCTTCC TGCAGCCAGA GAGGAGCCAG CGGGGCCCGC TGCTCAGGGC TATCTGGCGT 
GTGTTCCGGT CCACTTTCCT GCTGGGGACC CTCAGCCTGG TCATTAGCGA TGCCTTCAGG 
TTTGCTGTTC CCAAGCTCCT CAGTCTGTTT CTGGAGTTCA TGGGCGACCT CGAGTCCTCG 
GCTTGGACGG GCTGGCTCCT GGCTGTGCTG ATGTTCTTGT CGGCCTGCCT ACAGACACTG 
TTTGAACAGC AGTACATGTA CAGAGTCAAG GTCCTGCAGA TGAGGCTGCG AACAGCCATC 
ACTGGCCTGG TGTACAGAAA GGTCCTGGTC CTGTCCAGTG GTTCCAGAAA GTCCAGTGCA 
GCAGGGGACG TGGTCAACCT GGTGTCAGTG GACGTACAGC GGCTGGTCGA GAGCATCCTC 
CACCTCAACG GGCTGTGGCT GCTCTTCCTG TGGATCATTG TGTGCTTTGT CTACCTGTGG 
CAGCTCCTTG GGCCCTCTGC CCTCACAGCC GTTGCTGTCT TCCTGAGCCT TCTCCCCCTG 
AACTTCTTCA TTACCAAGAA GAGGAGCTTC CATCAGGAAG AACAGATGAG GCAGAAGGCC 
TCCCGAGCAC GGCTCACCAG CTCCATGCTC AGAACTGTGA GAACCATCAA GTCCCACGGC 
TGGGAGTGTG CCTTCCTGGA GCGACTCCTG CATATCCGGG GCCAGGAGCT AGGTGCCCTG 
AAGACCTCCG CCTTCCTCTT CTCTGTGTCT CTCGTGTCCT TCCAAGTGTC TACATTTCTG 
GTGGCGCTGG TTGTGTTTGC TGTCCACACC CTGGTGGCAG AGGACAACGC CATGGATGCG 
GAGAAGGCGT TTGTGACGCT CACGGTGCTC AGCATCCTTA ACAAAGCCCA GGCCTTCCTC 
CCCTTCTCTG TGCACTGCCT CGTTCAGGCT CGGGTGTCCT TTGACCGCCT AGCTGCTTTC 
CTGTGCCTGG AAGAAGTAGA CCCCAATGGC ATGGTCTTGA GTCCCTCCAG ATGCTCCTCG 
AAGGATCGAA TTTCTATACA CAATGGCACC TTCGCTTGGT CCCAGGAGAG CCCGCCCTGC 
CTGCACGGGA TCAACCTCAC CGTGCCCCAG GGCTGTCTGC TGGCTGTTGT GGGTCCAGTG 
GGGGCTGGAA AGTCCTCCCT GCTGTCTGCC CTGCTTGGGG AGCTGTTGAA GGTAGAAGGG 
TCTGTGAGCA TTGAGGGTTC CGTGGCCTAC GTGCCTCAGG AGGCTTGGGT CCAGAATACC 
TCTGTGGTGG AGAATGTGTG CTTCAGGCAG GAGCTGGATC TGCCATGGTT GCAGGAAGTT 
CTAGAAGCCT GTGCCTTGGG GTCTGATGTG GCCAGCTTCC CTGCAGGAGT TCACACCCCA 
GTAGGGGAGC AGGGCATGAA TCTTTCTGGG GGCCAGAAGC AGCGGCTGAG CTTGGCTCGG 
GCTGTGTACA GAAGGGCTGC TGTGTACCTG ATGGATGACC CCCTAGCAGC CCTGGATGCG 
CATGTCAGCC AGGAAGTCTT CAAACAGGTC ATTGGCCCCA GTGGACTTCT CCAAGGTACG 
ACTCGGATCC TTGTAACACA CACGCTGCAT GTCCTGCCCC AAGCTGACCA GATCCTGGTG 
CTGGCCAATG GGACCATCGC AGAGATGGGC TCCTACCAAG ACCTTCTGCA TAGGAACGGA 
GCCCTGGTGG GTCTTCTGGA TGGAGCCAGA CAGCCTGCAG GCGAAGGAGA AGGAGAAGCA 
CATGCTGCAG CCACCAGTGA TGACCTTGGA GGCTTTTCTG GAGGTGGGAC GCCCACGCGC 
AGACCAGAGA GGCCCAGACC CAGTGACGCA GCCCCTGTGA AGGGCAGTAC TTCAGAGGCA 
CAGATGGAGC CTTCTCTGGA TGACGTTGAG GTCACTGGAC TGACAGCAGG AGAGGACAGT 
GTGCAGTATG GCCGGGTGAA GAGCGCCACA TACCTGAGCT ACCTGCGGGC GGTGGGCACA 
CCGCTCTGCA CCTACACCCT GTTCCTCTTC CTCTGCCAGC AAGTGGCGTC CTTCTGCCAA 
GGCTACTGGC TGAGCCTCTG GGCCGACGAC CCGGTCGTGG ATGGGAAGCA GATGCATTCA 
GCCCTGCGTG GCTCCATCTT TGGACTCCTT GGCTGTCTGC AAGCCATCGG ACTGTTTGCC 
TCCATGGCTG CGGTGTTCCT GGGTGGAGCC CGAGCTTCAT GCCTGCTTTT CCGGAGCCTC 
CTCTGGGACG TGGCTCGCTC TCCCATTGGC TTCTTTGAGC GCACACCAGT CGGGAACCTG 
CTGAACCGTT TTTCCAAGGA GACGGACATA GTGGATGTGG ACATCCCAGA CAAGATGAGG 
ACCCTGCTGA CCTATGCCTT TGGACTCCTG GAGGTTGGCC TGGCAGTGTC GATGGCCACA 
CCACTGGCTA TTGTGGCCAT CCTACCTCTT ATGCTCCTTT ATGCTGGGTT TCAGAGCCTC 
TACGTGGCCA CATGTTGCCA GCTGAGACGC CTGGAGTCGG CCAGTTACTC CTCAGTGTGT 
TCCCATCTGG CTGAGACCTT CCAGGGCAGT CAGGTGGTCA GGGCCTTCCA GGCCCAGGGG 
CCCTTCACAG CTCAGCACGA TGCCCTCATG GATGAGAACC AGAGGATCAG TTTCCCGAGG 
CTGGTGGCTG ACAGGTGGCT GGCTGCCAAC CTGGAGCTCC TGGGGAATGG CCTGGTGTTT 
GTGGCCGCTA CATGTGCTGT GCTGAGCAAG GCTCACCTGA GTGCTGGCCT CGCGGGCTTC 
TCGGTTTCTG CTGCCCTCCA GGTAACACAG ACTCTGCAGT GGGTGGTCCG CAGCTGGACA 
GATCTGGAGA ACAGCATGGT GGCCGTGGAG CGAGTACAGG ACTACGTTCA CACCCCCAAG 
GAGGCTCCCT GGAGGCTGCC CTCCTCTGCA GCCCAGCCTC TCTGGCCCTG TGGGGGACAG 
ATTGAGTTCC GAGACTTTGG GCTCAGACAC CGACCAGAGC TGCCCATGGC TGTGCAGGGT 
GTGTCCCTGA AGATCCATGC AGGGGAGAAG GTGGGCATCG TGGGCAGGAC AGGGGCCGGG 
AAGTCCTCCC TGACTTGGGG CCTGCTGCGG CTTCAGGAGG CCACTGAGGG TGGTATTTGG 
ATCGATGGGG TCCCCATCAC CGACATGGGG CTGCACACAC TGCGGTCCAG AATCACCATC 
ATCCCTCAGG ACCCTGTCCT GTTCCCGGGC TCGCTGCGGA TGAACCTGGA CCTGCTTCAG 
GAGAACACAG ATGAGGGCAT CTGGGCAGCG CTGGAGACGG TGCAGCTCAA GGCCTTCGTG 
ACCAGCCTGC CTGGCCAGCT GCAGTATGAG TGCTCAGGCC AGGGAGATGA CCTGAGTGTG 
GGTCAGAAGC AGCTCCTGTG TCTGGCACGT GCCCTTCTCC GGAAAACCCA GATCCTCATC 
CTGGATGAAG CCACTGCCTC CGTGGACCCA GGGACGGAGA TACAGATGCA GGCGGCCCTC 
GAGCGCTGGT TTGCACAGTG TACAGTGCTG CTCATTGCTC ACCGCCTGCG CTCCGTGATG 
AACTGCGCCA GGGTTCTAGT CATGGATGAG GGGCAGGTGG CAGAGAGTGG CAGTCCAGCA 
CAGCTGCTGG CCCAGAAAGG CCTGTTTTAC AGGCTAGCCC AGGAGTCGGG CCTAGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Abcc6 ( XM_008759419.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008757641.1 Rattus norvegicus ATP binding cassette subfamily C member 6 (Abcc6), transcript variant X3, mRNA.

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CloneID	ORa22787
Clone ID Related Accession (Same CDS sequence)	XM_006229159.2 , XM_008759419.2
Accession Version	XM_008759419.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4200bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	multidrug resistance-associated protein 6 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008759419.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCCCAGG CCCCAGAGCT TCTCATTCAC CCTACCGTGT GGCTCACCAC CATGAGCTTC 
GCCACCTTCC TGATCCACAT GGAGAGAAAG AAGGGGGTCC GTGCATCTGG GTTGTTGTTC 
GGGTACTGGC TGCTCTGCTG CCTCGTGCCA GCCATCGACA CTGTCCAGCA GGCCTCCGCA 
GGGAGCTTCC GCCAGGAGCC CCTCCACCAC CTGGCCACCT ACCTGTGCTT GTCCCTGGTG 
GTGGCAGAGC TGGTGCTGTC TTGTCTGGTA GACCAGCCAC CCTTCTTCTC GGAAGACTCC 
AAGCCATTGA ATCCATGTCC AGAGGCCGAG GCCTCTTTTC CCTCCAAGGC CATGTTCTGG 
TGGGCCTCTG GACTGCTATG GAAGGGCTAC AGGAAACTGC TGGGGCCAAA AGACCTCTGG 
TCACTTGAGA GAGAAAACTC TTCAGAAGAA CTTGTTTCCC AGCTGGAAAG AGAATGGAGG 
AGGAACTTCA GTGAGCTGCC GGGGCACAAA GGGCACAGTG GTATGGGGAC CCCCGAGACA 
GAGGCCTTCC TGCAGCCAGA GAGGAGCCAG CGGGGCCCGC TGCTCAGGGC TATCTGGCGT 
GTGTTCCGGT CCACTTTCCT GCTGGGGACC CTCAGCCTGG TCATTAGCGA TGCCTTCAGG 
TTTGCTGTTC CCAAGCTCCT CAGTCTGTTT CTGGAGTTCA TGGGCGACCT CGAGTCCTCG 
GCTTGGACGG GCTGGCTCCT GGCTGTGCTG ATGTTCTTGT CGGCCTGCCT ACAGACACTG 
TTTGAACAGC AGTACATGTA CAGAGTCAAG GTCCTGCAGA TGAGGCTGCG AACAGCCATC 
ACTGGCCTGG TGTACAGAAA GGTCCTGGTC CTGTCCAGTG GTTCCAGAAA GTCCAGTGCA 
GCAGGGGACG TGGTCAACCT GGTGTCAGTG GACGTACAGC GGCTGGTCGA GAGCATCCTC 
CACCTCAACG GGCTGTGGCT GCTCTTCCTG TGGATCATTG TGTGCTTTGT CTACCTGTGG 
CAGCTCCTTG GGCCCTCTGC CCTCACAGCC GTTGCTGTCT TCCTGAGCCT TCTCCCCCTG 
AACTTCTTCA TTACCAAGAA GAGGAGCTTC CATCAGGAAG AACAGATGAG GCAGAAGGCC 
TCCCGAGCAC GGCTCACCAG CTCCATGCTC AGAACTGTGA GAACCATCAA GTCCCACGGC 
TGGGAGTGTG CCTTCCTGGA GCGACTCCTG CATATCCGGG GCCAGGAGCT AGGTGCCCTG 
AAGACCTCCG CCTTCCTCTT CTCTGTGTCT CTCGTGTCCT TCCAAGTGTC TACATTTCTG 
GTGGCGCTGG TTGTGTTTGC TGTCCACACC CTGGTGGCAG AGGACAACGC CATGGATGCG 
GAGAAGGCGT TTGTGACGCT CACGGTGCTC AGCATCCTTA ACAAAGCCCA GGCCTTCCTC 
CCCTTCTCTG TGCACTGCCT CGTTCAGGCT CGGGTGTCCT TTGACCGCCT AGCTGCTTTC 
CTGTGCCTGG AAGAAGTAGA CCCCAATGGC ATGGTCTTGA GTCCCTCCAG ATGCTCCTCG 
AAGGATCGAA TTTCTATACA CAATGGCACC TTCGCTTGGT CCCAGGAGAG CCCGCCCTGC 
CTGCACGGGA TCAACCTCAC CGTGCCCCAG GGCTGTCTGC TGGCTGTTGT GGGTCCAGTG 
GGGGCTGGAA AGTCCTCCCT GCTGTCTGCC CTGCTTGGGG AGCTGTTGAA GGTAGAAGGG 
TCTGTGAGCA TTGAGGGTTC CGTGGCCTAC GTGCCTCAGG AGGCTTGGGT CCAGAATACC 
TCTGTGGTGG AGAATGTGTG CTTCAGGCAG GAGCTGGATC TGCCATGGTT GCAGGAAGTT 
CTAGAAGCCT GTGCCTTGGG GTCTGATGTG GCCAGCTTCC CTGCAGGAGT TCACACCCCA 
GTAGGGGAGC AGGGCATGAA TCTTTCTGGG GGCCAGAAGC AGCGGCTGAG CTTGGCTCGG 
GCTGTGTACA GAAGGGCTGC TGTGTACCTG ATGGATGACC CCCTAGCAGC CCTGGATGCG 
CATGTCAGCC AGGAAGTCTT CAAACAGGTC ATTGGCCCCA GTGGACTTCT CCAAGGTACG 
ACTCGGATCC TTGTAACACA CACGCTGCAT GTCCTGCCCC AAGCTGACCA GATCCTGGTG 
CTGGCCAATG GGACCATCGC AGAGATGGGC TCCTACCAAG ACCTTCTGCA TAGGAACGGA 
GCCCTGGTGG GTCTTCTGGA TGGAGCCAGA CAGCCTGCAG GCGAAGGAGA AGGAGAAGCA 
CATGCTGCAG CCACCAGTGA TGACCTTGGA GGCTTTTCTG GAGGTGGGAC GCCCACGCGC 
AGACCAGAGA GGCCCAGACC CAGTGACGCA GCCCCTGTGA AGGGCAGTAC TTCAGAGGCA 
CAGATGGAGC CTTCTCTGGA TGACGTTGAG GTCACTGGAC TGACAGCAGG AGAGGACAGT 
GTGCAGTATG GCCGGGTGAA GAGCGCCACA TACCTGAGCT ACCTGCGGGC GGTGGGCACA 
CCGCTCTGCA CCTACACCCT GTTCCTCTTC CTCTGCCAGC AAGTGGCGTC CTTCTGCCAA 
GGCTACTGGC TGAGCCTCTG GGCCGACGAC CCGGTCGTGG ATGGGAAGCA GATGCATTCA 
GCCCTGCGTG GCTCCATCTT TGGACTCCTT GGCTGTCTGC AAGCCATCGG ACTGTTTGCC 
TCCATGGCTG CGGTGTTCCT GGGTGGAGCC CGAGCTTCAT GCCTGCTTTT CCGGAGCCTC 
CTCTGGGACG TGGCTCGCTC TCCCATTGGC TTCTTTGAGC GCACACCAGT CGGGAACCTG 
CTGAACCGTT TTTCCAAGGA GACGGACATA GTGGATGTGG ACATCCCAGA CAAGATGAGG 
ACCCTGCTGA CCTATGCCTT TGGACTCCTG GAGGTTGGCC TGGCAGTGTC GATGGCCACA 
CCACTGGCTA TTGTGGCCAT CCTACCTCTT ATGCTCCTTT ATGCTGGGTT TCAGAGCCTC 
TACGTGGCCA CATGTTGCCA GCTGAGACGC CTGGAGTCGG CCAGTTACTC CTCAGTGTGT 
TCCCATCTGG CTGAGACCTT CCAGGGCAGT CAGGTGGTCA GGGCCTTCCA GGCCCAGGGG 
CCCTTCACAG CTCAGCACGA TGCCCTCATG GATGAGAACC AGAGGATCAG TTTCCCGAGG 
CTGGTGGCTG ACAGGTGGCT GGCTGCCAAC CTGGAGCTCC TGGGGAATGG CCTGGTGTTT 
GTGGCCGCTA CATGTGCTGT GCTGAGCAAG GCTCACCTGA GTGCTGGCCT CGCGGGCTTC 
TCGGTTTCTG CTGCCCTCCA GGTAACACAG ACTCTGCAGT GGGTGGTCCG CAGCTGGACA 
GATCTGGAGA ACAGCATGGT GGCCGTGGAG CGAGTACAGG ACTACGTTCA CACCCCCAAG 
GAGGCTCCCT GGAGGCTGCC CTCCTCTGCA GCCCAGCCTC TCTGGCCCTG TGGGGGACAG 
ATTGAGTTCC GAGACTTTGG GCTCAGACAC CGACCAGAGC TGCCCATGGC TGTGCAGGGT 
GTGTCCCTGA AGATCCATGC AGGGGAGAAG GTGGGCATCG TGGGCAGGAC AGGGGCCGGG 
AAGTCCTCCC TGACTTGGGG CCTGCTGCGG CTTCAGGAGG CCACTGAGGG TGGTATTTGG 
ATCGATGGGG TCCCCATCAC CGACATGGGG CTGCACACAC TGCGGTCCAG AATCACCATC 
ATCCCTCAGG ACCCTGTCCT GTTCCCGGGC TCGCTGCGGA TGAACCTGGA CCTGCTTCAG 
GAGAACACAG ATGAGGGCAT CTGGGCAGCG CTGGAGACGG TGCAGCTCAA GGCCTTCGTG 
ACCAGCCTGC CTGGCCAGCT GCAGTATGAG TGCTCAGGCC AGGGAGATGA CCTGAGTGTG 
GGTCAGAAGC AGCTCCTGTG TCTGGCACGT GCCCTTCTCC GGAAAACCCA GATCCTCATC 
CTGGATGAAG CCACTGCCTC CGTGGACCCA GGGACGGAGA TACAGATGCA GGCGGCCCTC 
GAGCGCTGGT TTGCACAGTG TACAGTGCTG CTCATTGCTC ACCGCCTGCG CTCCGTGATG 
AACTGCGCCA GGGTTCTAGT CATGGATGAG GGGCAGGTGG CAGAGAGTGG CAGTCCAGCA 
CAGCTGCTGG CCCAGAAAGG CCTGTTTTAC AGGCTAGCCC AGGAGTCGGG CCTAGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008757641.1
CDS	633..4832
Translation	MPQAPELLIHPTVWLTTMSFATFLIHMERKKGVRASGLLFGYWLLCCLVPAIDTVQQASAGSFRQEPLHHLATYLCLSLVVAELVLSCLVDQPPFFSEDSKPLNPCPEAEASFPSKAMFWWASGLLWKGYRKLLGPKDLWSLERENSSEELVSQLEREWRRNFSELPGHKGHSGMGTPETEAFLQPERSQRGPLLRAIWRVFRSTFLLGTLSLVISDAFRFAVPKLLSLFLEFMGDLESSAWTGWLLAVLMFLSACLQTLFEQQYMYRVKVLQMRLRTAITGLVYRKVLVLSSGSRKSSAAGDVVNLVSVDVQRLVESILHLNGLWLLFLWIIVCFVYLWQLLGPSALTAVAVFLSLLPLNFFITKKRSFHQEEQMRQKASRARLTSSMLRTVRTIKSHGWECAFLERLLHIRGQELGALKTSAFLFSVSLVSFQVSTFLVALVVFAVHTLVAEDNAMDAEKAFVTLTVLSILNKAQAFLPFSVHCLVQARVSFDRLAAFLCLEEVDPNGMVLSPSRCSSKDRISIHNGTFAWSQESPPCLHGINLTVPQGCLLAVVGPVGAGKSSLLSALLGELLKVEGSVSIEGSVAYVPQEAWVQNTSVVENVCFRQELDLPWLQEVLEACALGSDVASFPAGVHTPVGEQGMNLSGGQKQRLSLARAVYRRAAVYLMDDPLAALDAHVSQEVFKQVIGPSGLLQGTTRILVTHTLHVLPQADQILVLANGTIAEMGSYQDLLHRNGALVGLLDGARQPAGEGEGEAHAAATSDDLGGFSGGGTPTRRPERPRPSDAAPVKGSTSEAQMEPSLDDVEVTGLTAGEDSVQYGRVKSATYLSYLRAVGTPLCTYTLFLFLCQQVASFCQGYWLSLWADDPVVDGKQMHSALRGSIFGLLGCLQAIGLFASMAAVFLGGARASCLLFRSLLWDVARSPIGFFERTPVGNLLNRFSKETDIVDVDIPDKMRTLLTYAFGLLEVGLAVSMATPLAIVAILPLMLLYAGFQSLYVATCCQLRRLESASYSSVCSHLAETFQGSQVVRAFQAQGPFTAQHDALMDENQRISFPRLVADRWLAANLELLGNGLVFVAATCAVLSKAHLSAGLAGFSVSAALQVTQTLQWVVRSWTDLENSMVAVERVQDYVHTPKEAPWRLPSSAAQPLWPCGGQIEFRDFGLRHRPELPMAVQGVSLKIHAGEKVGIVGRTGAGKSSLTWGLLRLQEATEGGIWIDGVPITDMGLHTLRSRITIIPQDPVLFPGSLRMNLDLLQENTDEGIWAALETVQLKAFVTSLPGQLQYECSGQGDDLSVGQKQLLCLARALLRKTQILILDEATASVDPGTEIQMQAALERWFAQCTVLLIAHRLRSVMNCARVLVMDEGQVAESGSPAQLLAQKGLFYRLAQESGLA

Target ORF information:

RefSeq Version	XM_008759419.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ATP binding cassette subfamily C member 6 (Abcc6), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008759419.2

ORF Insert Sequence:

ATGCCCCAGG CCCCAGAGCT TCTCATTCAC CCTACCGTGT GGCTCACCAC CATGAGCTTC 
GCCACCTTCC TGATCCACAT GGAGAGAAAG AAGGGGGTCC GTGCATCTGG GTTGTTGTTC 
GGGTACTGGC TGCTCTGCTG CCTCGTGCCA GCCATCGACA CTGTCCAGCA GGCCTCCGCA 
GGGAGCTTCC GCCAGGAGCC CCTCCACCAC CTGGCCACCT ACCTGTGCTT GTCCCTGGTG 
GTGGCAGAGC TGGTGCTGTC TTGTCTGGTA GACCAGCCAC CCTTCTTCTC GGAAGACTCC 
AAGCCATTGA ATCCATGTCC AGAGGCCGAG GCCTCTTTTC CCTCCAAGGC CATGTTCTGG 
TGGGCCTCTG GACTGCTATG GAAGGGCTAC AGGAAACTGC TGGGGCCAAA AGACCTCTGG 
TCACTTGAGA GAGAAAACTC TTCAGAAGAA CTTGTTTCCC AGCTGGAAAG AGAATGGAGG 
AGGAACTTCA GTGAGCTGCC GGGGCACAAA GGGCACAGTG GTATGGGGAC CCCCGAGACA 
GAGGCCTTCC TGCAGCCAGA GAGGAGCCAG CGGGGCCCGC TGCTCAGGGC TATCTGGCGT 
GTGTTCCGGT CCACTTTCCT GCTGGGGACC CTCAGCCTGG TCATTAGCGA TGCCTTCAGG 
TTTGCTGTTC CCAAGCTCCT CAGTCTGTTT CTGGAGTTCA TGGGCGACCT CGAGTCCTCG 
GCTTGGACGG GCTGGCTCCT GGCTGTGCTG ATGTTCTTGT CGGCCTGCCT ACAGACACTG 
TTTGAACAGC AGTACATGTA CAGAGTCAAG GTCCTGCAGA TGAGGCTGCG AACAGCCATC 
ACTGGCCTGG TGTACAGAAA GGTCCTGGTC CTGTCCAGTG GTTCCAGAAA GTCCAGTGCA 
GCAGGGGACG TGGTCAACCT GGTGTCAGTG GACGTACAGC GGCTGGTCGA GAGCATCCTC 
CACCTCAACG GGCTGTGGCT GCTCTTCCTG TGGATCATTG TGTGCTTTGT CTACCTGTGG 
CAGCTCCTTG GGCCCTCTGC CCTCACAGCC GTTGCTGTCT TCCTGAGCCT TCTCCCCCTG 
AACTTCTTCA TTACCAAGAA GAGGAGCTTC CATCAGGAAG AACAGATGAG GCAGAAGGCC 
TCCCGAGCAC GGCTCACCAG CTCCATGCTC AGAACTGTGA GAACCATCAA GTCCCACGGC 
TGGGAGTGTG CCTTCCTGGA GCGACTCCTG CATATCCGGG GCCAGGAGCT AGGTGCCCTG 
AAGACCTCCG CCTTCCTCTT CTCTGTGTCT CTCGTGTCCT TCCAAGTGTC TACATTTCTG 
GTGGCGCTGG TTGTGTTTGC TGTCCACACC CTGGTGGCAG AGGACAACGC CATGGATGCG 
GAGAAGGCGT TTGTGACGCT CACGGTGCTC AGCATCCTTA ACAAAGCCCA GGCCTTCCTC 
CCCTTCTCTG TGCACTGCCT CGTTCAGGCT CGGGTGTCCT TTGACCGCCT AGCTGCTTTC 
CTGTGCCTGG AAGAAGTAGA CCCCAATGGC ATGGTCTTGA GTCCCTCCAG ATGCTCCTCG 
AAGGATCGAA TTTCTATACA CAATGGCACC TTCGCTTGGT CCCAGGAGAG CCCGCCCTGC 
CTGCACGGGA TCAACCTCAC CGTGCCCCAG GGCTGTCTGC TGGCTGTTGT GGGTCCAGTG 
GGGGCTGGAA AGTCCTCCCT GCTGTCTGCC CTGCTTGGGG AGCTGTTGAA GGTAGAAGGG 
TCTGTGAGCA TTGAGGGTTC CGTGGCCTAC GTGCCTCAGG AGGCTTGGGT CCAGAATACC 
TCTGTGGTGG AGAATGTGTG CTTCAGGCAG GAGCTGGATC TGCCATGGTT GCAGGAAGTT 
CTAGAAGCCT GTGCCTTGGG GTCTGATGTG GCCAGCTTCC CTGCAGGAGT TCACACCCCA 
GTAGGGGAGC AGGGCATGAA TCTTTCTGGG GGCCAGAAGC AGCGGCTGAG CTTGGCTCGG 
GCTGTGTACA GAAGGGCTGC TGTGTACCTG ATGGATGACC CCCTAGCAGC CCTGGATGCG 
CATGTCAGCC AGGAAGTCTT CAAACAGGTC ATTGGCCCCA GTGGACTTCT CCAAGGTACG 
ACTCGGATCC TTGTAACACA CACGCTGCAT GTCCTGCCCC AAGCTGACCA GATCCTGGTG 
CTGGCCAATG GGACCATCGC AGAGATGGGC TCCTACCAAG ACCTTCTGCA TAGGAACGGA 
GCCCTGGTGG GTCTTCTGGA TGGAGCCAGA CAGCCTGCAG GCGAAGGAGA AGGAGAAGCA 
CATGCTGCAG CCACCAGTGA TGACCTTGGA GGCTTTTCTG GAGGTGGGAC GCCCACGCGC 
AGACCAGAGA GGCCCAGACC CAGTGACGCA GCCCCTGTGA AGGGCAGTAC TTCAGAGGCA 
CAGATGGAGC CTTCTCTGGA TGACGTTGAG GTCACTGGAC TGACAGCAGG AGAGGACAGT 
GTGCAGTATG GCCGGGTGAA GAGCGCCACA TACCTGAGCT ACCTGCGGGC GGTGGGCACA 
CCGCTCTGCA CCTACACCCT GTTCCTCTTC CTCTGCCAGC AAGTGGCGTC CTTCTGCCAA 
GGCTACTGGC TGAGCCTCTG GGCCGACGAC CCGGTCGTGG ATGGGAAGCA GATGCATTCA 
GCCCTGCGTG GCTCCATCTT TGGACTCCTT GGCTGTCTGC AAGCCATCGG ACTGTTTGCC 
TCCATGGCTG CGGTGTTCCT GGGTGGAGCC CGAGCTTCAT GCCTGCTTTT CCGGAGCCTC 
CTCTGGGACG TGGCTCGCTC TCCCATTGGC TTCTTTGAGC GCACACCAGT CGGGAACCTG 
CTGAACCGTT TTTCCAAGGA GACGGACATA GTGGATGTGG ACATCCCAGA CAAGATGAGG 
ACCCTGCTGA CCTATGCCTT TGGACTCCTG GAGGTTGGCC TGGCAGTGTC GATGGCCACA 
CCACTGGCTA TTGTGGCCAT CCTACCTCTT ATGCTCCTTT ATGCTGGGTT TCAGAGCCTC 
TACGTGGCCA CATGTTGCCA GCTGAGACGC CTGGAGTCGG CCAGTTACTC CTCAGTGTGT 
TCCCATCTGG CTGAGACCTT CCAGGGCAGT CAGGTGGTCA GGGCCTTCCA GGCCCAGGGG 
CCCTTCACAG CTCAGCACGA TGCCCTCATG GATGAGAACC AGAGGATCAG TTTCCCGAGG 
CTGGTGGCTG ACAGGTGGCT GGCTGCCAAC CTGGAGCTCC TGGGGAATGG CCTGGTGTTT 
GTGGCCGCTA CATGTGCTGT GCTGAGCAAG GCTCACCTGA GTGCTGGCCT CGCGGGCTTC 
TCGGTTTCTG CTGCCCTCCA GGTAACACAG ACTCTGCAGT GGGTGGTCCG CAGCTGGACA 
GATCTGGAGA ACAGCATGGT GGCCGTGGAG CGAGTACAGG ACTACGTTCA CACCCCCAAG 
GAGGCTCCCT GGAGGCTGCC CTCCTCTGCA GCCCAGCCTC TCTGGCCCTG TGGGGGACAG 
ATTGAGTTCC GAGACTTTGG GCTCAGACAC CGACCAGAGC TGCCCATGGC TGTGCAGGGT 
GTGTCCCTGA AGATCCATGC AGGGGAGAAG GTGGGCATCG TGGGCAGGAC AGGGGCCGGG 
AAGTCCTCCC TGACTTGGGG CCTGCTGCGG CTTCAGGAGG CCACTGAGGG TGGTATTTGG 
ATCGATGGGG TCCCCATCAC CGACATGGGG CTGCACACAC TGCGGTCCAG AATCACCATC 
ATCCCTCAGG ACCCTGTCCT GTTCCCGGGC TCGCTGCGGA TGAACCTGGA CCTGCTTCAG 
GAGAACACAG ATGAGGGCAT CTGGGCAGCG CTGGAGACGG TGCAGCTCAA GGCCTTCGTG 
ACCAGCCTGC CTGGCCAGCT GCAGTATGAG TGCTCAGGCC AGGGAGATGA CCTGAGTGTG 
GGTCAGAAGC AGCTCCTGTG TCTGGCACGT GCCCTTCTCC GGAAAACCCA GATCCTCATC 
CTGGATGAAG CCACTGCCTC CGTGGACCCA GGGACGGAGA TACAGATGCA GGCGGCCCTC 
GAGCGCTGGT TTGCACAGTG TACAGTGCTG CTCATTGCTC ACCGCCTGCG CTCCGTGATG 
AACTGCGCCA GGGTTCTAGT CATGGATGAG GGGCAGGTGG CAGAGAGTGG CAGTCCAGCA 
CAGCTGCTGG CCCAGAAAGG CCTGTTTTAC AGGCTAGCCC AGGAGTCGGG CCTAGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Abcc6 Knockout Rat Model Highlights the?Role of Liver in PPi Homeostasis in?Pseudoxanthoma Elasticum.
The Journal of investigative dermatology137(5)1025-1032(2017 May)
Li Q,Kingman J,van de Wetering K,Tannouri S,Sundberg JP,Uitto J

ABCC6-mediated ATP secretion by the liver is the main source of the mineralization inhibitor inorganic pyrophosphate in the systemic circulation-brief report.
Arteriosclerosis, thrombosis, and vascular biology34(9)1985-9(2014 Sep)
Jansen RS,Duijst S,Mahakena S,Sommer D,Szeri F,V?radi A,Plomp A,Bergen AA,Oude Elferink RP,Borst P,van de Wetering K

Chronic kidney disease results in deficiency of ABCC6, the novel inhibitor of vascular calcification.
American journal of nephrology40(1)51-5(2014)
Lau WL,Liu S,Vaziri ND

Effect of inflammation on molecular targets and drug transporters.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques15(3)361-75(2012)
Hanafy S,El-Kadi AO,Jamali F

A mouse model of ?-thalassemia shows a liver-specific down-regulation of Abcc6 expression.
The American journal of pathology178(2)774-83(2011 Feb)
Martin L,Douet V,VanWart CM,Heller MB,Le Saux O

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Abcc6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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