Bdkrb1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Early Increased Bradykinin 1 Receptor Contributes to Hemorrhagic Transformation After Ischemic Stroke in Type 1 Diabetic Rats.
Sang H, Qiu Z, Cai J, Lan W, Yu L, Zhang H, Li M, Xie Y, Guo R, Ye R, Liu X, Liu L, Zhang R
Translational stroke research8(6)597-611(2017 Dec)

Cardiac morphofunctional characteristics of transgenic rats with overexpression of the bradykinin B1 receptor in the endothelium.
Levy RF, Serra AJ, Antonio EL, Dos Santos L, Bocalini DS, Pesquero JB, Bader M, Merino VF, de Oliveira HA, de Arruda Veiga EC, Silva JA Jr, Tucci PJ
Physiological research66(6)925-932(2017 Dec)

Experimental periodontitis in rats potentiates inflammation at a distant site: Role of B
Prestes AP, Machado WM, Oliveira JG, Olchanheski LR Jr, Santos FA, Alves GF, Prudente AS, Otuki MF, Paludo KS, Sordi R, Fernandes D
Life sciences(2017 Dec)

Expression, distribution and function of kinin B1 receptor in the rat diabetic retina.
Hachana S, Bhat M, S?n?cal J, Hupp?-Gourgues F, Couture R, Vaucher E
British journal of pharmacology(2017 Dec)

Mas receptor antagonist abolished relaxation while bradykinin receptor antagonist only slightly reduced it, suggesting that bradykinin-induced vasorelaxation is regulated also by other mechanisms than the classical BR1/BR2 pathway.
Title: Bradykinin -induced vasodilatation: Role of age, ACE1-inhibitory peptide, mas- and bradykinin receptors.

data imply in a possible participation of B1R in the short term memory impairment observed in traumatic brain injury, neuroinflammation and neurodegeneration
Title: Kinin B1 receptor mediates memory impairment in the rat hippocampus.

Kinin B1R contributes to acute gouty attacks, including the ones facilitated by ACEi.
Title: The role of kinin B1 receptor and the effect of angiotensin I-converting enzyme inhibition on acute gout attacks in rodents.

Findings suggest that bradykinin 1 receptor and bradykinin 2 receptor have detrimental and beneficial effects, respectively in diabetic cerebral ischaemia.
Title: Opposite roles of bradykinin B1 and B2 receptors during cerebral ischaemia-reperfusion injury in experimental diabetic rats.

Data suggest that kinin B1R is upregulated by the oxidative stress in the brain of insulin-resistant rats and its activation causes stereotypic nocifensive behavior through the release of substance P, glutamate and NO.
Title: Brain kinin B1 receptor is upregulated by the oxidative stress and its activation leads to stereotypic nociceptive behavior in insulin-resistant rats.