Mcam cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Mcam
Entrez Gene ID	78967
Full Name	melanoma cell adhesion molecule
Synonyms	CD146,Muc18
General protein information	Preferred Names melanoma cell adhesion molecule Names cell surface glycoprotein MUC18 gicerin l-gicerin melanoma-associated antigen MUC18
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 8 Map Location: 8q22
Summary	may act as a cell adhesion molecule; may play a role in tumor growth and invasion [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_023983.3	NP_076473.2	cell surface glycoprotein MUC18 isoform 1 precursor
NM_001034009.1	NP_001029181.1	cell surface glycoprotein MUC18 isoform 2 precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	MCAM	XP_001149681.2
Rattus norvegicus (Norway rat)	Mcam	NP_076473.2
Xenopus tropicalis (tropical clawed frog)	mcam	XP_004916103.1
Canis lupus familiaris (dog)	MCAM	XP_546486.3
Danio rerio (zebrafish)	LOC566921	XP_005172069.1
Homo sapiens (human)	MCAM	NP_006491.2
Mus musculus (house mouse)	Mcam	NP_075548.2
Danio rerio (zebrafish)	mcamb	NP_001012367.2
Gallus gallus (chicken)	MCAM	NP_001004768.1
Danio rerio (zebrafish)	LOC101884730	XP_005172072.1

Gene Ontology
Bibliography

Related articles in PubMed

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.
Barallobre-Barreiro J, Oklu R, Lynch M, Fava M, Baig F, Yin X, Barwari T, Potier DN, Albadawi H, Jahangiri M, Porter KE, Watkins MT, Misra S, Stoughton J, Mayr M
Cardiovascular research110(3)419-30(2016 06)

MicroRNA 329 suppresses angiogenesis by targeting CD146.
Wang P, Luo Y, Duan H, Xing S, Zhang J, Lu D, Feng J, Yang D, Song L, Yan X
Molecular and cellular biology33(18)3689-99(2013 Sep)

Endothelial cell adhesion molecule CD146: implications for its role in the pathogenesis of COPD.
Kratzer A, Chu HW, Salys J, Moumen Z, Leberl M, Bowler R, Cool C, Zamora M, Taraseviciene-Stewart L
The Journal of pathology230(4)388-98(2013 Aug)

CD146 and insulin-like growth factor 2 mRNA-binding protein 3 predict prognosis of asbestos-induced rat mesothelioma.
Okazaki Y, Nagai H, Chew SH, Li J, Funahashi S, Tsujimura T, Toyokuni S
Cancer science104(8)989-95(2013 Aug)

Correction of diabetic erectile dysfunction with adipose derived stem cells modified with the vascular endothelial growth factor gene in a rodent diabetic model.
Liu G, Sun X, Bian J, Wu R, Guan X, Ouyang B, Huang Y, Xiao H, Luo D, Atala A, Zhang Y, Deng C
PloS one8(8)e72790(2013)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Alterations in CD146 are involved in the basic etiology of COPD/pulmonary emphysema.
Title: Endothelial cell adhesion molecule CD146: implications for its role in the pathogenesis of COPD.

Gicerin might promote the interaction of tumor cells with a hepatic endothelium, thus leading to the hepatic metastasis of colon adenocarcinomas.
Title: Involvement of gicerin, a cell adhesion molecule, in the portal metastasis of rat colorectal adenocarcinoma cells.

Increase of gicerin expression by NGF promotes the gicerin-gicerin homophilic interaction resulting in the neurite extension.
Title: Gicerin/CD146 is involved in neurite extension of NGF-treated PC12 cells.

expression of gicerin was increased in the rat carotid arteries after balloon injury. Gicerin might be involved in the arteriosclerotic neointima formation in the artery.
Title: Induction of gicerin/CD146 in the rat carotid artery after balloon injury.

The following Mcam gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mcam cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa12980	NM_001034009.1 Latest version!	Rattus norvegicus melanoma cell adhesion molecule (Mcam), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$356.30 $509.00
ORa13012	NM_023983.3 Latest version!	Rattus norvegicus melanoma cell adhesion molecule (Mcam), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$384.30 $549.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Mcam ( NM_001034009.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001029181.1 Rattus norvegicus melanoma cell adhesion molecule (Mcam), transcript variant 2, mRNA.

Price & Availability↑

CloneID	ORa12980
Clone ID Related Accession (Same CDS sequence)	NM_001034009.1
Accession Version	NM_001034009.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1821bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Rattus norvegicus(Norway rat)
Product	cell surface glycoprotein MUC18 isoform 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC070916.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC070916.1, AB035507.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGGGCTGC CCAGGCTGGT CTGCGCCTTC TTATTCGCTG CCTGCTGCTG CTGTCGCAGC 
GCCACGGGTG TGCCAGGAGA GGAAAAGCAG CCCACACCCA CGCCGGACCC GGTGGAGGTA 
GAAGTGGGCA ACACGGCCCT TCTGAAGTGT GGCCCCGCAC ATCCCTCAGG CAACTTCAGC 
CAAGTGGAAT GGTTTTTGAT TCACAAGGAG AGGCAGATAC CCATTTTCCG TGTGCACCAG 
GGCAAGGGCC AGAGTGAACC TGGGGAATAT GAACACCGCC TCAGCCTCCA CGGCCCAGGA 
GCTACTCTGG CCCTGAGTCA AGTCACTCCC CATGATGATC GGATGTTCCT GTGTAAGAGC 
AAGCAGCCAC GGCCCCAGGA TCACTATGTT CAGCTGCAAG TCTACAAGGC TCCAGAGGAG 
CCAACTATCC AAGCCAACGT GCTGGGCATC CACGTGGACA TACAAGAGCT TAAGGAGGTT 
GCTACCTGTG TGGGGAGGAA TGGCTACCCC ATTCCTCAAG TCATCTGGTA CAAGAATGGC 
CGGCCCTTGC AAGAGGAGGA GAACCGCGTT CATATCCAGT CGTCACAGAC CGTGGAGTCC 
AGTGGCTTGT ACACCTTGAA GAGTGTTCTA AGTGCACGGC TAGTCAAGGA GGACAAAGAT 
GCCCAGTTTT ACTGTGAACT CAGCTACCGG CTGCCCAGTG GGAACCGCAT GAAGGAATCT 
AAGGAGGTCA CTGTCCCTGT CTTATACCCT GCAGAAAAAG TGTGGGTGGA GGTAGAACCC 
GTGGGACTGC TGAAGGAAGG GGACCATGTG AAGATCAGGT GTCTGACTGA CGGCAACCCT 
CAACCCCACT TCACTATCAA CAAGAAGAAC CCCAGCACTG AGGAGATGGA AGAGGAAAGC 
ACCGATGAAA ACGGTCTCCT GTCCTTGGAG CCCGCCCAGA AGCACCACAG TGGGGTCTAC 
CAATGTCAGA GCCTAGACTT GGAAACTACA GTTATGCTGT CGAGTGACCC CCTGGAGCTG 
CTGGTGAACT ATGTGTCTGA TGTTCAAGTG GATCCAACTG CCCCTGAAGT CCAGGAAGGT 
GATAGCCTCA CACTGACCTG TAAGGCAGAG AGTAACCAGG ACCTTGAGTT TGAGTGGCTG 
AGAGACAAGA CAGGCCAGCT TCTGGGAAAG GGGCCCATCC TTCAGCTAAA CAACGTGAAA 
AGGGAAGCAG GGGGAAGATA TCTCTGTGTG GCATCTGTCC CCAGCGTTCC TGGCTTGAAT 
CGCACACGGC GGGTCAGCGT GGGCATTTTT GGGTCCCCGT GGATGGCAGC AAAGGAGAGG 
AAGGTGTGGG CGCAAGAGAA TGCAATGCTG AATCTGTCTT GTGAGGCTTC AGGCCATCCT 
CAGCCCACCA TCTCCTGGAA TATCAATGGC TCGGCAACTG AATGGAACCC AGATCCTCAG 
ACAGTAGTGA GCACCTTGAA TGTCCTTGTG ACCCCAGAGC TTCTGGAGAC CGGTGCAGAA 
TGTACAGCCT CCAACTCCCT GGGCTCAAAC ACCACGGTCA TCATTCTGAA GCTCGTCACT 
TTAACCACCC TCACACCTGA CTCCAGCCAA ACCACTGGCC TCAGCACCCC CACAGTCAGT 
CCTCACAGCA GAGCCAACAG CACCTCCACA GAGAAAAAGC TGCCACAGCA GGAGAGCAAA 
GGTGTGGTCA TCGTGGCTGT GATAGTATGT ACGCTGGTGC TTGCTGTACT GGGCGCTACC 
CTCTATTACT TCTACAAGAA GGGCAAACTG CCTTGTGGAC GCTCAGGAAA ACAGGAGATG 
GAGAGAAATA CATCGATCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001029181.1
CDS	19..1839
Translation	MGLPRLVCAFLFAACCCCRSATGVPGEEKQPTPTPDPVEVEVGNTALLKCGPAHPSGNFSQVEWFLIHKERQIPIFRVHQGKGQSEPGEYEHRLSLHGPGATLALSQVTPHDDRMFLCKSKQPRPQDHYVQLQVYKAPEEPTIQANVLGIHVDIQELKEVATCVGRNGYPIPQVIWYKNGRPLQEEENRVHIQSSQTVESSGLYTLKSVLSARLVKEDKDAQFYCELSYRLPSGNRMKESKEVTVPVLYPAEKVWVEVEPVGLLKEGDHVKIRCLTDGNPQPHFTINKKNPSTEEMEEESTDENGLLSLEPAQKHHSGVYQCQSLDLETTVMLSSDPLELLVNYVSDVQVDPTAPEVQEGDSLTLTCKAESNQDLEFEWLRDKTGQLLGKGPILQLNNVKREAGGRYLCVASVPSVPGLNRTRRVSVGIFGSPWMAAKERKVWAQENAMLNLSCEASGHPQPTISWNINGSATEWNPDPQTVVSTLNVLVTPELLETGAECTASNSLGSNTTVIILKLVTLTTLTPDSSQTTGLSTPTVSPHSRANSTSTEKKLPQQESKGVVIVAVIVCTLVLAVLGATLYYFYKKGKLPCGRSGKQEMERNTSI

Target ORF information:

RefSeq Version	NM_001034009.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus melanoma cell adhesion molecule (Mcam), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001034009.1

ORF Insert Sequence:

ATGGGGCTGC CCAGGCTGGT CTGCGCCTTC TTATTCGCTG CCTGCTGCTG CTGTCGCAGC 
GCCACGGGTG TGCCAGGAGA GGAAAAGCAG CCCACACCCA CGCCGGACCC GGTGGAGGTA 
GAAGTGGGCA ACACGGCCCT TCTGAAGTGT GGCCCCGCAC ATCCCTCAGG CAACTTCAGC 
CAAGTGGAAT GGTTTTTGAT TCACAAGGAG AGGCAGATAC CCATTTTCCG TGTGCACCAG 
GGCAAGGGCC AGAGTGAACC TGGGGAATAT GAACACCGCC TCAGCCTCCA CGGCCCAGGA 
GCTACTCTGG CCCTGAGTCA AGTCACTCCC CATGATGATC GGATGTTCCT GTGTAAGAGC 
AAGCAGCCAC GGCCCCAGGA TCACTATGTT CAGCTGCAAG TCTACAAGGC TCCAGAGGAG 
CCAACTATCC AAGCCAACGT GCTGGGCATC CACGTGGACA TACAAGAGCT TAAGGAGGTT 
GCTACCTGTG TGGGGAGGAA TGGCTACCCC ATTCCTCAAG TCATCTGGTA CAAGAATGGC 
CGGCCCTTGC AAGAGGAGGA GAACCGCGTT CATATCCAGT CGTCACAGAC CGTGGAGTCC 
AGTGGCTTGT ACACCTTGAA GAGTGTTCTA AGTGCACGGC TAGTCAAGGA GGACAAAGAT 
GCCCAGTTTT ACTGTGAACT CAGCTACCGG CTGCCCAGTG GGAACCGCAT GAAGGAATCT 
AAGGAGGTCA CTGTCCCTGT CTTATACCCT GCAGAAAAAG TGTGGGTGGA GGTAGAACCC 
GTGGGACTGC TGAAGGAAGG GGACCATGTG AAGATCAGGT GTCTGACTGA CGGCAACCCT 
CAACCCCACT TCACTATCAA CAAGAAGAAC CCCAGCACTG AGGAGATGGA AGAGGAAAGC 
ACCGATGAAA ACGGTCTCCT GTCCTTGGAG CCCGCCCAGA AGCACCACAG TGGGGTCTAC 
CAATGTCAGA GCCTAGACTT GGAAACTACA GTTATGCTGT CGAGTGACCC CCTGGAGCTG 
CTGGTGAACT ATGTGTCTGA TGTTCAAGTG GATCCAACTG CCCCTGAAGT CCAGGAAGGT 
GATAGCCTCA CACTGACCTG TAAGGCAGAG AGTAACCAGG ACCTTGAGTT TGAGTGGCTG 
AGAGACAAGA CAGGCCAGCT TCTGGGAAAG GGGCCCATCC TTCAGCTAAA CAACGTGAAA 
AGGGAAGCAG GGGGAAGATA TCTCTGTGTG GCATCTGTCC CCAGCGTTCC TGGCTTGAAT 
CGCACACGGC GGGTCAGCGT GGGCATTTTT GGGTCCCCGT GGATGGCAGC AAAGGAGAGG 
AAGGTGTGGG CGCAAGAGAA TGCAATGCTG AATCTGTCTT GTGAGGCTTC AGGCCATCCT 
CAGCCCACCA TCTCCTGGAA TATCAATGGC TCGGCAACTG AATGGAACCC AGATCCTCAG 
ACAGTAGTGA GCACCTTGAA TGTCCTTGTG ACCCCAGAGC TTCTGGAGAC CGGTGCAGAA 
TGTACAGCCT CCAACTCCCT GGGCTCAAAC ACCACGGTCA TCATTCTGAA GCTCGTCACT 
TTAACCACCC TCACACCTGA CTCCAGCCAA ACCACTGGCC TCAGCACCCC CACAGTCAGT 
CCTCACAGCA GAGCCAACAG CACCTCCACA GAGAAAAAGC TGCCACAGCA GGAGAGCAAA 
GGTGTGGTCA TCGTGGCTGT GATAGTATGT ACGCTGGTGC TTGCTGTACT GGGCGCTACC 
CTCTATTACT TCTACAAGAA GGGCAAACTG CCTTGTGGAC GCTCAGGAAA ACAGGAGATG 
GAGAGAAATA CATCGATCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mcam ( NM_023983.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_076473.2 Rattus norvegicus melanoma cell adhesion molecule (Mcam), transcript variant 1, mRNA.

Price & Availability↑

CloneID	ORa13012
Clone ID Related Accession (Same CDS sequence)	NM_023983.3
Accession Version	NM_023983.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1947bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Rattus norvegicus(Norway rat)
Product	cell surface glycoprotein MUC18 isoform 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC070916.1 and AB035506.1. On Oct 6, 2005 this sequence version replaced NM_023983.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB035506.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGGGCTGC CCAGGCTGGT CTGCGCCTTC TTATTCGCTG CCTGCTGCTG CTGTCGCAGC 
GCCACGGGTG TGCCAGGAGA GGAAAAGCAG CCCACACCCA CGCCGGACCC GGTGGAGGTA 
GAAGTGGGCA ACACGGCCCT TCTGAAGTGT GGCCCCGCAC ATCCCTCAGG CAACTTCAGC 
CAAGTGGAAT GGTTTTTGAT TCACAAGGAG AGGCAGATAC CCATTTTCCG TGTGCACCAG 
GGCAAGGGCC AGAGTGAACC TGGGGAATAT GAACACCGCC TCAGCCTCCA CGGCCCAGGA 
GCTACTCTGG CCCTGAGTCA AGTCACTCCC CATGATGATC GGATGTTCCT GTGTAAGAGC 
AAGCAGCCAC GGCCCCAGGA TCACTATGTT CAGCTGCAAG TCTACAAGGC TCCAGAGGAG 
CCAACTATCC AAGCCAACGT GCTGGGCATC CACGTGGACA TACAAGAGCT TAAGGAGGTT 
GCTACCTGTG TGGGGAGGAA TGGCTACCCC ATTCCTCAAG TCATCTGGTA CAAGAATGGC 
CGGCCCTTGC AAGAGGAGGA GAACCGCGTT CATATCCAGT CGTCACAGAC CGTGGAGTCC 
AGTGGCTTGT ACACCTTGAA GAGTGTTCTA AGTGCACGGC TAGTCAAGGA GGACAAAGAT 
GCCCAGTTTT ACTGTGAACT CAGCTACCGG CTGCCCAGTG GGAACCGCAT GAAGGAATCT 
AAGGAGGTCA CTGTCCCTGT CTTATACCCT GCAGAAAAAG TGTGGGTGGA GGTAGAACCC 
GTGGGACTGC TGAAGGAAGG GGACCATGTG AAGATCAGGT GTCTGACTGA CGGCAACCCT 
CAACCCCACT TCACTATCAA CAAGAAGAAC CCCAGCACTG AGGAGATGGA AGAGGAAAGC 
ACCGATGAAA ACGGTCTCCT GTCCTTGGAG CCCGCCCAGA AGCACCACAG TGGGGTCTAC 
CAATGTCAGA GCCTAGACTT GGAAACTACA GTTATGCTGT CGAGTGACCC CCTGGAGCTG 
CTGGTGAACT ATGTGTCTGA TGTTCAAGTG GATCCAACTG CCCCTGAAGT CCAGGAAGGT 
GATAGCCTCA CACTGACCTG TAAGGCAGAG AGTAACCAGG ACCTTGAGTT TGAGTGGCTG 
AGAGACAAGA CAGGCCAGCT TCTGGGAAAG GGGCCCATCC TTCAGCTAAA CAACGTGAAA 
AGGGAAGCAG GGGGAAGATA TCTCTGTGTG GCATCTGTCC CCAGCGTTCC TGGCTTGAAT 
CGCACACGGC GGGTCAGCGT GGGCATTTTT GGGTCCCCGT GGATGGCAGC AAAGGAGAGG 
AAGGTGTGGG CGCAAGAGAA TGCAATGCTG AATCTGTCTT GTGAGGCTTC AGGCCATCCT 
CAGCCCACCA TCTCCTGGAA TATCAATGGC TCGGCAACTG AATGGAACCC AGATCCTCAG 
ACAGTAGTGA GCACCTTGAA TGTCCTTGTG ACCCCAGAGC TTCTGGAGAC CGGTGCAGAA 
TGTACAGCCT CCAACTCCCT GGGCTCAAAC ACCACGGTCA TCATTCTGAA GCTCGTCACT 
TTAACCACCC TCACACCTGA CTCCAGCCAA ACCACTGGCC TCAGCACCCC CACAGTCAGT 
CCTCACAGCA GAGCCAACAG CACCTCCACA GAGAAAAAGC TGCCACAGCA GGAGAGCAAA 
GGTGTGGTCA TCGTGGCTGT GATAGTATGT ACGCTGGTGC TTGCTGTACT GGGCGCTACC 
CTCTATTACT TCTACAAGAA GGGCAAACTG CCTTGTGGAC GCTCAGGAAA ACAGGAGATC 
ACGCTGCCCC CGACTCGTAA GAGTGAATTT GTAGTTGAAG TTAAGTCAGA TAAGCTCCCA 
GAAGAGATGG CTCTCCTTCA GGGCAGCAAC GGTGACAAGA GGGCTCCAGG AGACCAGGGA 
GAGAAATACA TCGATCTGAG GCATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_076473.2
CDS	19..1965
Translation	MGLPRLVCAFLFAACCCCRSATGVPGEEKQPTPTPDPVEVEVGNTALLKCGPAHPSGNFSQVEWFLIHKERQIPIFRVHQGKGQSEPGEYEHRLSLHGPGATLALSQVTPHDDRMFLCKSKQPRPQDHYVQLQVYKAPEEPTIQANVLGIHVDIQELKEVATCVGRNGYPIPQVIWYKNGRPLQEEENRVHIQSSQTVESSGLYTLKSVLSARLVKEDKDAQFYCELSYRLPSGNRMKESKEVTVPVLYPAEKVWVEVEPVGLLKEGDHVKIRCLTDGNPQPHFTINKKNPSTEEMEEESTDENGLLSLEPAQKHHSGVYQCQSLDLETTVMLSSDPLELLVNYVSDVQVDPTAPEVQEGDSLTLTCKAESNQDLEFEWLRDKTGQLLGKGPILQLNNVKREAGGRYLCVASVPSVPGLNRTRRVSVGIFGSPWMAAKERKVWAQENAMLNLSCEASGHPQPTISWNINGSATEWNPDPQTVVSTLNVLVTPELLETGAECTASNSLGSNTTVIILKLVTLTTLTPDSSQTTGLSTPTVSPHSRANSTSTEKKLPQQESKGVVIVAVIVCTLVLAVLGATLYYFYKKGKLPCGRSGKQEITLPPTRKSEFVVEVKSDKLPEEMALLQGSNGDKRAPGDQGEKYIDLRH

Target ORF information:

RefSeq Version	NM_023983.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus melanoma cell adhesion molecule (Mcam), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_023983.3

ORF Insert Sequence:

ATGGGGCTGC CCAGGCTGGT CTGCGCCTTC TTATTCGCTG CCTGCTGCTG CTGTCGCAGC 
GCCACGGGTG TGCCAGGAGA GGAAAAGCAG CCCACACCCA CGCCGGACCC GGTGGAGGTA 
GAAGTGGGCA ACACGGCCCT TCTGAAGTGT GGCCCCGCAC ATCCCTCAGG CAACTTCAGC 
CAAGTGGAAT GGTTTTTGAT TCACAAGGAG AGGCAGATAC CCATTTTCCG TGTGCACCAG 
GGCAAGGGCC AGAGTGAACC TGGGGAATAT GAACACCGCC TCAGCCTCCA CGGCCCAGGA 
GCTACTCTGG CCCTGAGTCA AGTCACTCCC CATGATGATC GGATGTTCCT GTGTAAGAGC 
AAGCAGCCAC GGCCCCAGGA TCACTATGTT CAGCTGCAAG TCTACAAGGC TCCAGAGGAG 
CCAACTATCC AAGCCAACGT GCTGGGCATC CACGTGGACA TACAAGAGCT TAAGGAGGTT 
GCTACCTGTG TGGGGAGGAA TGGCTACCCC ATTCCTCAAG TCATCTGGTA CAAGAATGGC 
CGGCCCTTGC AAGAGGAGGA GAACCGCGTT CATATCCAGT CGTCACAGAC CGTGGAGTCC 
AGTGGCTTGT ACACCTTGAA GAGTGTTCTA AGTGCACGGC TAGTCAAGGA GGACAAAGAT 
GCCCAGTTTT ACTGTGAACT CAGCTACCGG CTGCCCAGTG GGAACCGCAT GAAGGAATCT 
AAGGAGGTCA CTGTCCCTGT CTTATACCCT GCAGAAAAAG TGTGGGTGGA GGTAGAACCC 
GTGGGACTGC TGAAGGAAGG GGACCATGTG AAGATCAGGT GTCTGACTGA CGGCAACCCT 
CAACCCCACT TCACTATCAA CAAGAAGAAC CCCAGCACTG AGGAGATGGA AGAGGAAAGC 
ACCGATGAAA ACGGTCTCCT GTCCTTGGAG CCCGCCCAGA AGCACCACAG TGGGGTCTAC 
CAATGTCAGA GCCTAGACTT GGAAACTACA GTTATGCTGT CGAGTGACCC CCTGGAGCTG 
CTGGTGAACT ATGTGTCTGA TGTTCAAGTG GATCCAACTG CCCCTGAAGT CCAGGAAGGT 
GATAGCCTCA CACTGACCTG TAAGGCAGAG AGTAACCAGG ACCTTGAGTT TGAGTGGCTG 
AGAGACAAGA CAGGCCAGCT TCTGGGAAAG GGGCCCATCC TTCAGCTAAA CAACGTGAAA 
AGGGAAGCAG GGGGAAGATA TCTCTGTGTG GCATCTGTCC CCAGCGTTCC TGGCTTGAAT 
CGCACACGGC GGGTCAGCGT GGGCATTTTT GGGTCCCCGT GGATGGCAGC AAAGGAGAGG 
AAGGTGTGGG CGCAAGAGAA TGCAATGCTG AATCTGTCTT GTGAGGCTTC AGGCCATCCT 
CAGCCCACCA TCTCCTGGAA TATCAATGGC TCGGCAACTG AATGGAACCC AGATCCTCAG 
ACAGTAGTGA GCACCTTGAA TGTCCTTGTG ACCCCAGAGC TTCTGGAGAC CGGTGCAGAA 
TGTACAGCCT CCAACTCCCT GGGCTCAAAC ACCACGGTCA TCATTCTGAA GCTCGTCACT 
TTAACCACCC TCACACCTGA CTCCAGCCAA ACCACTGGCC TCAGCACCCC CACAGTCAGT 
CCTCACAGCA GAGCCAACAG CACCTCCACA GAGAAAAAGC TGCCACAGCA GGAGAGCAAA 
GGTGTGGTCA TCGTGGCTGT GATAGTATGT ACGCTGGTGC TTGCTGTACT GGGCGCTACC 
CTCTATTACT TCTACAAGAA GGGCAAACTG CCTTGTGGAC GCTCAGGAAA ACAGGAGATC 
ACGCTGCCCC CGACTCGTAA GAGTGAATTT GTAGTTGAAG TTAAGTCAGA TAAGCTCCCA 
GAAGAGATGG CTCTCCTTCA GGGCAGCAAC GGTGACAAGA GGGCTCCAGG AGACCAGGGA 
GAGAAATACA TCGATCTGAG GCATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.
Cardiovascular research110(3)419-30(2016 06)
Barallobre-Barreiro J,Oklu R,Lynch M,Fava M,Baig F,Yin X,Barwari T,Potier DN,Albadawi H,Jahangiri M,Porter KE,Watkins MT,Misra S,Stoughton J,Mayr M

MicroRNA 329 suppresses angiogenesis by targeting CD146.
Molecular and cellular biology33(18)3689-99(2013 Sep)
Wang P,Luo Y,Duan H,Xing S,Zhang J,Lu D,Feng J,Yang D,Song L,Yan X

Endothelial cell adhesion molecule CD146: implications for its role in the pathogenesis of COPD.
The Journal of pathology230(4)388-98(2013 Aug)
Kratzer A,Chu HW,Salys J,Moumen Z,Leberl M,Bowler R,Cool C,Zamora M,Taraseviciene-Stewart L

CD146 and insulin-like growth factor 2 mRNA-binding protein 3 predict prognosis of asbestos-induced rat mesothelioma.
Cancer science104(8)989-95(2013 Aug)
Okazaki Y,Nagai H,Chew SH,Li J,Funahashi S,Tsujimura T,Toyokuni S

Correction of diabetic erectile dysfunction with adipose derived stem cells modified with the vascular endothelial growth factor gene in a rodent diabetic model.
PloS one8(8)e72790(2013)
Liu G,Sun X,Bian J,Wu R,Guan X,Ouyang B,Huang Y,Xiao H,Luo D,Atala A,Zhang Y,Deng C

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Mcam cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報