Klrb1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Klrb1
Entrez Gene ID	689817
Full Name	killer cell lectin-like receptor subfamily B, member 1
Synonyms	Klrb1d,Klrb1f,Klrb1g,Klrb6,NKR-P1G,Nkr-p1e,Nkrp-1e
General protein information	Preferred Names killer cell lectin-like receptor subfamily B, member 1 Names killer cell lectin-like receptor subfamily B member 1 immunoreceptor NKR-P1E killer cell lectin-like receptor subfamily B member 1F killer cell lectin-like receptor subfamily B member 1G natural killer cell surface protein NKR-P1G natural killer lectin-like receptor 1E natural killer lectin-like receptor protein 1 e
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 4 Map Location: 4q42

mRNA and Protein(s)

mRNA	Protein	Name
XM_008763335.2	XP_008761557.1	killer cell lectin-like receptor subfamily B member 1 isoform X2
NM_001085405.1	NP_001078874.1	killer cell lectin-like receptor subfamily B member 1
XM_008763334.2	XP_008761556.1	killer cell lectin-like receptor subfamily B member 1 isoform X1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Klrb1	NP_001078874.1
Mus musculus (house mouse)	Klrb1	NP_001093388.1

Gene Ontology
Bibliography

Related articles in PubMed

Functional characterization of a conserved pair of NKR-P1 receptors expressed by NK cells and T lymphocytes in liver and gut.
Kveberg L, Sudworth A, Todros-Dawda I, Inngjerdingen M, Vaage JT
European journal of immunology45(2)501-12(2015 Feb)

Phylogenetic and functional conservation of the NKR-P1F and NKR-P1G receptors in rat and mouse.
Kveberg L, Dai KZ, Inngjerdingen M, Brooks CG, Fossum S, Vaage JT
Immunogenetics63(7)429-36(2011 Jul)

The complete inventory of receptors encoded by the rat natural killer cell gene complex.
Flornes LM, Nylenna ?, Saether PC, Daws MR, Dissen E, Fossum S
Immunogenetics62(8)521-30(2010 Aug)

Two major groups of rat NKR-P1 receptors can be distinguished based on chromosomal localization, phylogenetic analysis and Clr ligand binding.
Kveberg L, Dai KZ, Westgaard IH, Daws MR, Fossum S, Naper C, Vaage JT
European journal of immunology39(2)541-51(2009 Feb)

Cytomegalovirus evasion of innate immunity by subversion of the NKR-P1B:Clr-b missing-self axis.
Voigt S, Mesci A, Ettinger J, Fine JH, Chen P, Chou W, Carlyle JR
Immunity26(5)617-27(2007 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

NKR-P1F and NKR-P1G receptors expressed by NK cells and T lymphocytes in liver and gut have been functionally characterized.
Title: Functional characterization of a conserved pair of NKR-P1 receptors expressed by NK cells and T lymphocytes in liver and gut.

The following Klrb1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Klrb1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa10963	NM_001085405.1 Latest version!	Rattus norvegicus killer cell lectin-like receptor subfamily B, member 1 (Klrb1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
ORa50398	XM_008763334.2 Latest version!	Rattus norvegicus killer cell lectin-like receptor subfamily B, member 1 (Klrb1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa50399	XM_008763335.2 Latest version!	Rattus norvegicus killer cell lectin-like receptor subfamily B, member 1 (Klrb1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Klrb1 ( NM_001085405.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001078874.1 Rattus norvegicus killer cell lectin-like receptor subfamily B, member 1 (Klrb1), mRNA.

Price & Availability↑

CloneID	ORa10963
Clone ID Related Accession (Same CDS sequence)	NM_001085405.1
Accession Version	NM_001085405.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 645bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-09-15
Organism	Rattus norvegicus(Norway rat)
Product	killer cell lectin-like receptor subfamily B member 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from EF100680.1. On Apr 28, 2007 this sequence version replaced XM_001072129.1. ##Evidence-Data-START## Transcript exon combination :: DQ113420.1, DQ157011.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN02642649, SAMN02642806 [ECO:0000348] ##Evidence-Data-END##

ATGGATGCAC CAGTGCTCTA TGCTGAATTA CATTTAGCCA ACACCCAAGG GCTCAGGTGT 
ACATCACCTC CATCTCCCCG ACAAGATGCC TGTTGGGGAT CAGGCTGGCA CCGGGTGGCT 
CTGAAACTTG GCTGTGTTGG GCTGATCCTT CTTCTAATGG GACTCAGTGT CTTAGTGGGA 
TTCTTGGTGC AAAAACCACC AATAGAAAAA TGCAGTGTGG CTGTTCAAGA GAACAAGACT 
GAACCAACAG TGAGATCAAC CATTCTAGAG TGCCCAAGAG ATTGGCATTT GCACTGGAAT 
AAATGCTTAT TTATTTCTCA AACTTCCAGA CCTTGGGCTG AAGGTCTCGC TGACTGTTCT 
TTGAGAGGAG CCACTTTGCT GCTCATTGGA GATGGAAAAG AATTGAAATT ATTGCAGGAC 
TTCTCAAAGG GAAAAGGACA ACAATTTTTT ATTGGACTAA AATATGTACA AGAGGACAAG 
GTTTGGAAGT GGATGAATGG TTCTATTTTA AATACTAATC TATTACGCAT CACCGGCAAG 
AACGAAGAAA ACAGCTGTGC CCTCATCTCA CACACAGAAG TGTTTTCAGA TTCTTGTTCT 
TCAGACAACC ATTGGATCTG CCAAAAGACC CTGAAACGTG TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001078874.1
CDS	1..645
Translation	MDAPVLYAELHLANTQGLRCTSPPSPRQDACWGSGWHRVALKLGCVGLILLLMGLSVLVGFLVQKPPIEKCSVAVQENKTEPTVRSTILECPRDWHLHWNKCLFISQTSRPWAEGLADCSLRGATLLLIGDGKELKLLQDFSKGKGQQFFIGLKYVQEDKVWKWMNGSILNTNLLRITGKNEENSCALISHTEVFSDSCSSDNHWICQKTLKRV

Target ORF information:

RefSeq Version	NM_001085405.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus killer cell lectin-like receptor subfamily B, member 1 (Klrb1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001085405.1

ORF Insert Sequence:

ATGGATGCAC CAGTGCTCTA TGCTGAATTA CATTTAGCCA ACACCCAAGG GCTCAGGTGT 
ACATCACCTC CATCTCCCCG ACAAGATGCC TGTTGGGGAT CAGGCTGGCA CCGGGTGGCT 
CTGAAACTTG GCTGTGTTGG GCTGATCCTT CTTCTAATGG GACTCAGTGT CTTAGTGGGA 
TTCTTGGTGC AAAAACCACC AATAGAAAAA TGCAGTGTGG CTGTTCAAGA GAACAAGACT 
GAACCAACAG TGAGATCAAC CATTCTAGAG TGCCCAAGAG ATTGGCATTT GCACTGGAAT 
AAATGCTTAT TTATTTCTCA AACTTCCAGA CCTTGGGCTG AAGGTCTCGC TGACTGTTCT 
TTGAGAGGAG CCACTTTGCT GCTCATTGGA GATGGAAAAG AATTGAAATT ATTGCAGGAC 
TTCTCAAAGG GAAAAGGACA ACAATTTTTT ATTGGACTAA AATATGTACA AGAGGACAAG 
GTTTGGAAGT GGATGAATGG TTCTATTTTA AATACTAATC TATTACGCAT CACCGGCAAG 
AACGAAGAAA ACAGCTGTGC CCTCATCTCA CACACAGAAG TGTTTTCAGA TTCTTGTTCT 
TCAGACAACC ATTGGATCTG CCAAAAGACC CTGAAACGTG TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Klrb1 ( XM_008763334.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008761556.1 Rattus norvegicus killer cell lectin-like receptor subfamily B, member 1 (Klrb1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa50398
Clone ID Related Accession (Same CDS sequence)	XM_008763334.2
Accession Version	XM_008763334.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 561bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	killer cell lectin-like receptor subfamily B member 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008763334.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATGCAC CAGTGCTCTA TGCTGAATTA CATTTAGCCA ACACCCAAGG GCTCAGGTGT 
ACATCACCTC CATCTCCCCG ACAAGATGCC TGTTGGGGAT CAGGCTGGCA CCGGGTGGCT 
CTGAAACTTG GCTGTGTTGG GCTGATCCTT CTTCTAATGG GACTCAGTGT CTTAGTGGGA 
TTCTTGGTGC AAAAACCACC AATAGAAAAA TGCAGTGTGG CTGTTCAAGA GAACAAGACT 
GAACCAACAG TGAGATCAAC CATTCTAGAG TGCCCAAGAG ATTGGCATTT GCACTGGAAT 
AAATGCTTAT TTATTTCTCA AACTTCCAGA CCTTGGGCTG AAGGTCTCGC TGACTGTTCT 
TTGAGAGGAG CCACTTTGCT GCTCATTGGA GATGGAAAAG AATTGAAATT ATTGCAGGAC 
TTCTCAAAGG GAAAAGGACA ACAATTTTTT ATTGGACTAA AATATGTACA AGAGGACAAG 
GTTTGGAAGT GGATGAATGG TTCTATTTTA AATACTAATC TGAATCTGCA GGAACTCCAG 
ATGAGTCCAG TGCTGCTATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008761556.1
CDS	60..620
Translation	MDAPVLYAELHLANTQGLRCTSPPSPRQDACWGSGWHRVALKLGCVGLILLLMGLSVLVGFLVQKPPIEKCSVAVQENKTEPTVRSTILECPRDWHLHWNKCLFISQTSRPWAEGLADCSLRGATLLLIGDGKELKLLQDFSKGKGQQFFIGLKYVQEDKVWKWMNGSILNTNLNLQELQMSPVLL

Target ORF information:

RefSeq Version	XM_008763334.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus killer cell lectin-like receptor subfamily B, member 1 (Klrb1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008763334.2

ORF Insert Sequence:

ATGGATGCAC CAGTGCTCTA TGCTGAATTA CATTTAGCCA ACACCCAAGG GCTCAGGTGT 
ACATCACCTC CATCTCCCCG ACAAGATGCC TGTTGGGGAT CAGGCTGGCA CCGGGTGGCT 
CTGAAACTTG GCTGTGTTGG GCTGATCCTT CTTCTAATGG GACTCAGTGT CTTAGTGGGA 
TTCTTGGTGC AAAAACCACC AATAGAAAAA TGCAGTGTGG CTGTTCAAGA GAACAAGACT 
GAACCAACAG TGAGATCAAC CATTCTAGAG TGCCCAAGAG ATTGGCATTT GCACTGGAAT 
AAATGCTTAT TTATTTCTCA AACTTCCAGA CCTTGGGCTG AAGGTCTCGC TGACTGTTCT 
TTGAGAGGAG CCACTTTGCT GCTCATTGGA GATGGAAAAG AATTGAAATT ATTGCAGGAC 
TTCTCAAAGG GAAAAGGACA ACAATTTTTT ATTGGACTAA AATATGTACA AGAGGACAAG 
GTTTGGAAGT GGATGAATGG TTCTATTTTA AATACTAATC TGAATCTGCA GGAACTCCAG 
ATGAGTCCAG TGCTGCTATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Klrb1 ( XM_008763335.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008761557.1 Rattus norvegicus killer cell lectin-like receptor subfamily B, member 1 (Klrb1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa50399
Clone ID Related Accession (Same CDS sequence)	XM_008763335.2
Accession Version	XM_008763335.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 525bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	killer cell lectin-like receptor subfamily B member 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008763335.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATGCAC CAGTGCTCTA TGCTGAATTA CATTTAGCCA ACACCCAAGG GCTCAGGTGT 
ACATCACCTC CATCTCCCCG ACAAGATGCC TGTTGGGGAT CAGGCTGGCA CCGGGTGGCT 
CTGAAACTTG GCTGTGTTGG GCTGATCCTT CTTCTAATGG GACTCAGTGT CTTAGTGGGA 
TTCTTGGTGC AAAAACCACC AATAGAAAAA TGCAGTGTGG CTGTTCAAGA GAACAAGACT 
GAACCAACAG TGAGATCAAC CATTCTAGAG TGCCCAAGAG ATTGGCATTT GCACTGGAAT 
AAATGCTTAT TTATTTCTCA AACTTCCAGA CCTTGGGCTG AAGGTCTCGC TGACTGTTCT 
TTGAGAGGAG CCACTTTGCT GCTCATTGGA GATGGAAAAG AATTGAAATT ATTGCAGGAC 
TTCTCAAAGG GAAAAGGACA ACAATTTTTT ATTGGACTAA AATATGTACA AGAGGACAAG 
GTTTGGAAGT GGATGAATGG TTCTATTTTA AATACTAATC TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008761557.1
CDS	60..584
Translation	MDAPVLYAELHLANTQGLRCTSPPSPRQDACWGSGWHRVALKLGCVGLILLLMGLSVLVGFLVQKPPIEKCSVAVQENKTEPTVRSTILECPRDWHLHWNKCLFISQTSRPWAEGLADCSLRGATLLLIGDGKELKLLQDFSKGKGQQFFIGLKYVQEDKVWKWMNGSILNTNL

Target ORF information:

RefSeq Version	XM_008763335.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus killer cell lectin-like receptor subfamily B, member 1 (Klrb1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008763335.2

ORF Insert Sequence:

ATGGATGCAC CAGTGCTCTA TGCTGAATTA CATTTAGCCA ACACCCAAGG GCTCAGGTGT 
ACATCACCTC CATCTCCCCG ACAAGATGCC TGTTGGGGAT CAGGCTGGCA CCGGGTGGCT 
CTGAAACTTG GCTGTGTTGG GCTGATCCTT CTTCTAATGG GACTCAGTGT CTTAGTGGGA 
TTCTTGGTGC AAAAACCACC AATAGAAAAA TGCAGTGTGG CTGTTCAAGA GAACAAGACT 
GAACCAACAG TGAGATCAAC CATTCTAGAG TGCCCAAGAG ATTGGCATTT GCACTGGAAT 
AAATGCTTAT TTATTTCTCA AACTTCCAGA CCTTGGGCTG AAGGTCTCGC TGACTGTTCT 
TTGAGAGGAG CCACTTTGCT GCTCATTGGA GATGGAAAAG AATTGAAATT ATTGCAGGAC 
TTCTCAAAGG GAAAAGGACA ACAATTTTTT ATTGGACTAA AATATGTACA AGAGGACAAG 
GTTTGGAAGT GGATGAATGG TTCTATTTTA AATACTAATC TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Functional characterization of a conserved pair of NKR-P1 receptors expressed by NK cells and T lymphocytes in liver and gut.
European journal of immunology45(2)501-12(2015 Feb)
Kveberg L,Sudworth A,Todros-Dawda I,Inngjerdingen M,Vaage JT

Phylogenetic and functional conservation of the NKR-P1F and NKR-P1G receptors in rat and mouse.
Immunogenetics63(7)429-36(2011 Jul)
Kveberg L,Dai KZ,Inngjerdingen M,Brooks CG,Fossum S,Vaage JT

The complete inventory of receptors encoded by the rat natural killer cell gene complex.
Immunogenetics62(8)521-30(2010 Aug)
Flornes LM,Nylenna ?,Saether PC,Daws MR,Dissen E,Fossum S

Two major groups of rat NKR-P1 receptors can be distinguished based on chromosomal localization, phylogenetic analysis and Clr ligand binding.
European journal of immunology39(2)541-51(2009 Feb)
Kveberg L,Dai KZ,Westgaard IH,Daws MR,Fossum S,Naper C,Vaage JT

Cytomegalovirus evasion of innate immunity by subversion of the NKR-P1B:Clr-b missing-self axis.
Immunity26(5)617-27(2007 May)
Voigt S,Mesci A,Ettinger J,Fine JH,Chen P,Chou W,Carlyle JR