Kin cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Kin
Entrez Gene ID	689197
Full Name	Kin17 DNA and RNA binding protein
General protein information	Preferred Names Kin17 DNA and RNA binding protein Names DNA/RNA-binding protein KIN17 antigenic determinant of rec-A protein homolog
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 17 Map Location: 17q12.3

mRNA and Protein(s)

mRNA	Protein	Name
XM_006254252.3	XP_006254314.1	DNA/RNA-binding protein KIN17 isoform X1
NM_001109529.1	NP_001102999.1	DNA/RNA-binding protein KIN17

Pathways from BioSystems

Homologies

Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010352	XP_311588.3
Xenopus tropicalis (tropical clawed frog)	kin	NP_001004824.1
Danio rerio (zebrafish)	kin	NP_001025257.2
Homo sapiens (human)	KIN	NP_036443.1
Pan troglodytes (chimpanzee)	KIN	XP_001148768.1
	KIN	XP_001107965.1
Rattus norvegicus (Norway rat)	Kin	NP_001102999.1
Gallus gallus (chicken)	KIN	XP_004937540.1
Drosophila melanogaster (fruit fly)	kin17	NP_649212.2
Arabidopsis thaliana (thale cress)	AT1G55460	NP_564690.1
Bos taurus (cattle)	KIN	NP_001094569.1
Mus musculus (house mouse)	Kin	NP_079556.1
Oryza sativa (rice)	Os03g0570300	NP_001050519.1
Canis lupus familiaris (dog)	KIN	XP_535194.2
Caenorhabditis elegans (roundworm)	CELE_Y52B11A.9	NP_492860.1

Gene Ontology
Bibliography

Related articles in PubMed

A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity.
Cloutier P, Lavall?e-Adam M, Faubert D, Blanchette M, Coulombe B
PLoS genetics9(1)e1003210(2013)

A tandem of SH3-like domains participates in RNA binding in KIN17, a human protein activated in response to genotoxics.
le Maire A, Schiltz M, Stura EA, Pinon-Lataillade G, Couprie J, Moutiez M, Gondry M, Angulo JF, Zinn-Justin S
Journal of molecular biology364(4)764-76(2006 Dec)

8-oxoguanine DNA glycosylase, but not Kin17 protein, is translocated and differentially regulated by estrogens in rat brain cells.
Araneda S, Pelloux S, Radicella JP, Angulo J, Kitahama K, Gysling K, Forray MI
Neuroscience136(1)135-46(2005)

Selective interactions of human kin17 and RPA proteins with chromatin and the nuclear matrix in a DNA damage- and cell cycle-regulated manner.
Miccoli L, Biard DS, Frouin I, Harper F, Maga G, Angulo JF
Nucleic acids research31(14)4162-75(2003 Jul)

Participation of kin17 protein in replication factories and in other DNA transactions mediated by high molecular weight nuclear complexes.
Biard DS, Miccoli L, Despras E, Harper F, Pichard E, Cr?minon C, Angulo JF
Molecular cancer research : MCR1(7)519-31(2003 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Estrogens differentially regulate expression of 8-oxoguanine DNA glycosylase, but not of Kin17 protein, in specific regions of rat brain. (Kin17 protein)
Title: 8-oxoguanine DNA glycosylase, but not Kin17 protein, is translocated and differentially regulated by estrogens in rat brain cells.

The following Kin gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Kin cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa10221	NM_001109529.1 Latest version!	Rattus norvegicus Kin17 DNA and RNA binding protein (Kin), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa38051	XM_006254252.3 Latest version!	Rattus norvegicus Kin17 DNA and RNA binding protein (Kin), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Kin ( NM_001109529.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001102999.1 Rattus norvegicus Kin17 DNA and RNA binding protein (Kin), mRNA.

Price & Availability↑

CloneID	ORa10221
Clone ID Related Accession (Same CDS sequence)	NM_001109529.1
Accession Version	NM_001109529.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1179bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-27
Organism	Rattus norvegicus(Norway rat)
Product	DNA/RNA-binding protein KIN17
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473990.1. On Oct 4, 2007 this sequence version replaced XM_001066201.1. ##Evidence-Data-START## Transcript exon combination :: FQ107678.1, FM067418.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGGCAAGT CAGATTTTCT GAGCCCCAAG GCCATCGCGA ATAGAATTAA GTCTAAAGGG 
CTGCAGAAGC TTCGCTGGTA CTGCCAGATG TGCCAAAAAC AATGCCGCGA CGAGAATGGT 
TTCAAGTGTC ACTGTATGTC CGAGTCTCAT CAAAGACAGC TGTTGCTGGC TTCAGAAAAT 
CCTCAGCAGT TTATGGATTA TTTTTCAGAG GAATTCCGAA ATGACTTTCT GGAACTTCTG 
AGAAGACGCT TTGGCACTAA GAGAGTCCAC AACAACATTG TCTACAATGA ATACATCAGC 
CACCGAGAGC ACATCCACAT GAACGCCACT CAGTGGGAGA CGCTGACTGA CTTTACCAAG 
TGGCTGGGCA GAGAGGGCTT GTGTAAAGTG GATGAGACAC CAAAAGGCTG GTACATTCAG 
TACATAGACA GAGACCCAGA AACTATACGT CGGCAACTGG AATTAGAAAA AAAGAAGAAG 
CAAGATCTTG ACGATGAAGA AAAAACTGCC AAATTCATTG AGGAGCAGGT GAGAAGAGGC 
CTAGAAGGGA AAGAGCAGGA GACGCCTGTC TTTACAGAGT TAAGTCGAGA AAATGATGAA 
GAAAAGGTCA CGTTCAATCT GAATAAAGGA GCGGGTAGCT CAGCGGGAGC AACAACGTCC 
AAGTCAAGCT CGCTGGGACC GAGCGCACTG AAGATGCTGG GGAGCACAGC ATCCGTGAGG 
CGGAAAGAGT CTTCACAGAG CTCAGCTCAG CCTGCGAAGA AGAAGAAGAA GTCTGCCCTG 
GATGAGATCA TGGAGATTGA GGAGGAAAAG AAAAGGACCG CACGGACAGA CTCCTGGTTA 
CAGCCTGGGA TCATTGTGAA AATTATAACG AAGAAGCTTG GGGAGAAATA CCACAAGAAG 
AAAGGGGTCG TTAAGGAAGT GATTGACAGA TACACAGCTG TGGTAAAGAT GACTGACTCC 
GGAGACAGGC TGAAACTGGA CCAGACTCAT TTAGAGACAG TCATTCCAGC CCCAGGGAAA 
AGAGTTCTAG TTTTAAACGG AGGCTACAGA GGAAATGAAG GCACCCTCGA GTCCATCAAT 
GAAAAGACTT TTTCAGCCAC GATAGTCATT GAAACGGGAC CTTTGAAAGG GCGCAGACTT 
GAAGGTATTC AGTATGAAGA CATATCTAAA CTTGCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001102999.1
CDS	48..1226
Translation	MGKSDFLSPKAIANRIKSKGLQKLRWYCQMCQKQCRDENGFKCHCMSESHQRQLLLASENPQQFMDYFSEEFRNDFLELLRRRFGTKRVHNNIVYNEYISHREHIHMNATQWETLTDFTKWLGREGLCKVDETPKGWYIQYIDRDPETIRRQLELEKKKKQDLDDEEKTAKFIEEQVRRGLEGKEQETPVFTELSRENDEEKVTFNLNKGAGSSAGATTSKSSSLGPSALKMLGSTASVRRKESSQSSAQPAKKKKKSALDEIMEIEEEKKRTARTDSWLQPGIIVKIITKKLGEKYHKKKGVVKEVIDRYTAVVKMTDSGDRLKLDQTHLETVIPAPGKRVLVLNGGYRGNEGTLESINEKTFSATIVIETGPLKGRRLEGIQYEDISKLA

Target ORF information:

RefSeq Version	NM_001109529.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Kin17 DNA and RNA binding protein (Kin), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001109529.1

ORF Insert Sequence:

ATGGGCAAGT CAGATTTTCT GAGCCCCAAG GCCATCGCGA ATAGAATTAA GTCTAAAGGG 
CTGCAGAAGC TTCGCTGGTA CTGCCAGATG TGCCAAAAAC AATGCCGCGA CGAGAATGGT 
TTCAAGTGTC ACTGTATGTC CGAGTCTCAT CAAAGACAGC TGTTGCTGGC TTCAGAAAAT 
CCTCAGCAGT TTATGGATTA TTTTTCAGAG GAATTCCGAA ATGACTTTCT GGAACTTCTG 
AGAAGACGCT TTGGCACTAA GAGAGTCCAC AACAACATTG TCTACAATGA ATACATCAGC 
CACCGAGAGC ACATCCACAT GAACGCCACT CAGTGGGAGA CGCTGACTGA CTTTACCAAG 
TGGCTGGGCA GAGAGGGCTT GTGTAAAGTG GATGAGACAC CAAAAGGCTG GTACATTCAG 
TACATAGACA GAGACCCAGA AACTATACGT CGGCAACTGG AATTAGAAAA AAAGAAGAAG 
CAAGATCTTG ACGATGAAGA AAAAACTGCC AAATTCATTG AGGAGCAGGT GAGAAGAGGC 
CTAGAAGGGA AAGAGCAGGA GACGCCTGTC TTTACAGAGT TAAGTCGAGA AAATGATGAA 
GAAAAGGTCA CGTTCAATCT GAATAAAGGA GCGGGTAGCT CAGCGGGAGC AACAACGTCC 
AAGTCAAGCT CGCTGGGACC GAGCGCACTG AAGATGCTGG GGAGCACAGC ATCCGTGAGG 
CGGAAAGAGT CTTCACAGAG CTCAGCTCAG CCTGCGAAGA AGAAGAAGAA GTCTGCCCTG 
GATGAGATCA TGGAGATTGA GGAGGAAAAG AAAAGGACCG CACGGACAGA CTCCTGGTTA 
CAGCCTGGGA TCATTGTGAA AATTATAACG AAGAAGCTTG GGGAGAAATA CCACAAGAAG 
AAAGGGGTCG TTAAGGAAGT GATTGACAGA TACACAGCTG TGGTAAAGAT GACTGACTCC 
GGAGACAGGC TGAAACTGGA CCAGACTCAT TTAGAGACAG TCATTCCAGC CCCAGGGAAA 
AGAGTTCTAG TTTTAAACGG AGGCTACAGA GGAAATGAAG GCACCCTCGA GTCCATCAAT 
GAAAAGACTT TTTCAGCCAC GATAGTCATT GAAACGGGAC CTTTGAAAGG GCGCAGACTT 
GAAGGTATTC AGTATGAAGA CATATCTAAA CTTGCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Kin ( XM_006254252.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006254314.1 Rattus norvegicus Kin17 DNA and RNA binding protein (Kin), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa38051
Clone ID Related Accession (Same CDS sequence)	XM_006254252.3
Accession Version	XM_006254252.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1044bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	DNA/RNA-binding protein KIN17 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005116.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006254252.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCGAGT CTCATCAAAG ACAGCTGTTG CTGGCTTCAG AAAATCCTCA GCAGTTTATG 
GATTATTTTT CAGAGGAATT CCGAAATGAC TTTCTGGAAC TTCTGAGAAG ACGCTTTGGC 
ACTAAGAGAG TCCACAACAA CATTGTCTAC AATGAATACA TCAGCCACCG AGAGCACATC 
CACATGAACG CCACTCAGTG GGAGACGCTG ACTGACTTTA CCAAGTGGCT GGGCAGAGAG 
GGCTTGTGTA AAGTGGATGA GACACCAAAA GGCTGGTACA TTCAGTACAT AGACAGAGAC 
CCAGAAACTA TACGTCGGCA ACTGGAATTA GAAAAAAAGA AGAAGCAAGA TCTTGACGAT 
GAAGAAAAAA CTGCCAAATT CATTGAGGAG CAGGTGAGAA GAGGCCTAGA AGGGAAAGAG 
CAGGAGACGC CTGTCTTTAC AGAGTTAAGT CGAGAAAATG ATGAAGAAAA GGTCACGTTC 
AATCTGAATA AAGGAGCGGG TAGCTCAGCG GGAGCAACAA CGTCCAAGTC AAGCTCGCTG 
GGACCGAGCG CACTGAAGAT GCTGGGGAGC ACAGCATCCG TGAGGCGGAA AGAGTCTTCA 
CAGAGCTCAG CTCAGCCTGC GAAGAAGAAG AAGAAGTCTG CCCTGGATGA GATCATGGAG 
ATTGAGGAGG AAAAGAAAAG GACCGCACGG ACAGACTCCT GGTTACAGCC TGGGATCATT 
GTGAAAATTA TAACGAAGAA GCTTGGGGAG AAATACCACA AGAAGAAAGG GGTCGTTAAG 
GAAGTGATTG ACAGATACAC AGCTGTGGTA AAGATGACTG ACTCCGGAGA CAGGCTGAAA 
CTGGACCAGA CTCATTTAGA GACAGTCATT CCAGCCCCAG GGAAAAGAGT TCTAGTTTTA 
AACGGAGGCT ACAGAGGAAA TGAAGGCACC CTCGAGTCCA TCAATGAAAA GACTTTTTCA 
GCCACGATAG TCATTGAAAC GGGACCTTTG AAAGGGCGCA GACTTGAAGG TATTCAGTAT 
GAAGACATAT CTAAACTTGC TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006254314.1
CDS	331..1374
Translation	MSESHQRQLLLASENPQQFMDYFSEEFRNDFLELLRRRFGTKRVHNNIVYNEYISHREHIHMNATQWETLTDFTKWLGREGLCKVDETPKGWYIQYIDRDPETIRRQLELEKKKKQDLDDEEKTAKFIEEQVRRGLEGKEQETPVFTELSRENDEEKVTFNLNKGAGSSAGATTSKSSSLGPSALKMLGSTASVRRKESSQSSAQPAKKKKKSALDEIMEIEEEKKRTARTDSWLQPGIIVKIITKKLGEKYHKKKGVVKEVIDRYTAVVKMTDSGDRLKLDQTHLETVIPAPGKRVLVLNGGYRGNEGTLESINEKTFSATIVIETGPLKGRRLEGIQYEDISKLA

Target ORF information:

RefSeq Version	XM_006254252.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Kin17 DNA and RNA binding protein (Kin), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006254252.3

ORF Insert Sequence:

ATGTCCGAGT CTCATCAAAG ACAGCTGTTG CTGGCTTCAG AAAATCCTCA GCAGTTTATG 
GATTATTTTT CAGAGGAATT CCGAAATGAC TTTCTGGAAC TTCTGAGAAG ACGCTTTGGC 
ACTAAGAGAG TCCACAACAA CATTGTCTAC AATGAATACA TCAGCCACCG AGAGCACATC 
CACATGAACG CCACTCAGTG GGAGACGCTG ACTGACTTTA CCAAGTGGCT GGGCAGAGAG 
GGCTTGTGTA AAGTGGATGA GACACCAAAA GGCTGGTACA TTCAGTACAT AGACAGAGAC 
CCAGAAACTA TACGTCGGCA ACTGGAATTA GAAAAAAAGA AGAAGCAAGA TCTTGACGAT 
GAAGAAAAAA CTGCCAAATT CATTGAGGAG CAGGTGAGAA GAGGCCTAGA AGGGAAAGAG 
CAGGAGACGC CTGTCTTTAC AGAGTTAAGT CGAGAAAATG ATGAAGAAAA GGTCACGTTC 
AATCTGAATA AAGGAGCGGG TAGCTCAGCG GGAGCAACAA CGTCCAAGTC AAGCTCGCTG 
GGACCGAGCG CACTGAAGAT GCTGGGGAGC ACAGCATCCG TGAGGCGGAA AGAGTCTTCA 
CAGAGCTCAG CTCAGCCTGC GAAGAAGAAG AAGAAGTCTG CCCTGGATGA GATCATGGAG 
ATTGAGGAGG AAAAGAAAAG GACCGCACGG ACAGACTCCT GGTTACAGCC TGGGATCATT 
GTGAAAATTA TAACGAAGAA GCTTGGGGAG AAATACCACA AGAAGAAAGG GGTCGTTAAG 
GAAGTGATTG ACAGATACAC AGCTGTGGTA AAGATGACTG ACTCCGGAGA CAGGCTGAAA 
CTGGACCAGA CTCATTTAGA GACAGTCATT CCAGCCCCAG GGAAAAGAGT TCTAGTTTTA 
AACGGAGGCT ACAGAGGAAA TGAAGGCACC CTCGAGTCCA TCAATGAAAA GACTTTTTCA 
GCCACGATAG TCATTGAAAC GGGACCTTTG AAAGGGCGCA GACTTGAAGG TATTCAGTAT 
GAAGACATAT CTAAACTTGC TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity.
PLoS genetics9(1)e1003210(2013)
Cloutier P,Lavall?e-Adam M,Faubert D,Blanchette M,Coulombe B

A tandem of SH3-like domains participates in RNA binding in KIN17, a human protein activated in response to genotoxics.
Journal of molecular biology364(4)764-76(2006 Dec)
le Maire A,Schiltz M,Stura EA,Pinon-Lataillade G,Couprie J,Moutiez M,Gondry M,Angulo JF,Zinn-Justin S

8-oxoguanine DNA glycosylase, but not Kin17 protein, is translocated and differentially regulated by estrogens in rat brain cells.
Neuroscience136(1)135-46(2005)
Araneda S,Pelloux S,Radicella JP,Angulo J,Kitahama K,Gysling K,Forray MI

Selective interactions of human kin17 and RPA proteins with chromatin and the nuclear matrix in a DNA damage- and cell cycle-regulated manner.
Nucleic acids research31(14)4162-75(2003 Jul)
Miccoli L,Biard DS,Frouin I,Harper F,Maga G,Angulo JF

Participation of kin17 protein in replication factories and in other DNA transactions mediated by high molecular weight nuclear complexes.
Molecular cancer research : MCR1(7)519-31(2003 May)
Biard DS,Miccoli L,Despras E,Harper F,Pichard E,Cr?minon C,Angulo JF

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Kin cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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