Tnfsf8 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tnfsf8
Entrez Gene ID	683163
Full Name	TNF superfamily member 8
Synonyms	Tnlg3a
General protein information	Preferred Names TNF superfamily member 8 Names tumor necrosis factor ligand superfamily member 8 CD30 antigen ligand tumor necrosis factor (ligand) superfamily, member 8 tumor necrosis factor ligand 3a tumor necrosis factor superfamily member 8
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 5 Map Location: 5q24
Summary	human homolog is associated with the expansion of specific T-helper 2 (Th2) subsets that produce IL-4 and express CD30 [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001319033.1	NP_001305962.1	tumor necrosis factor ligand superfamily member 8
XM_006238271.3	XP_006238333.1	tumor necrosis factor ligand superfamily member 8 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	TNFSF8	NP_001235.1
Gallus gallus (chicken)	TNFSF8	NP_989740.1
Canis lupus familiaris (dog)	TNFSF8	XP_855435.1
Bos taurus (cattle)	TNFSF8	NP_001020378.1
Rattus norvegicus (Norway rat)	Tnfsf8	XP_003750005.1
Pan troglodytes (chimpanzee)	TNFSF8	XP_520212.1
	TNFSF8	XP_001099524.1
Mus musculus (house mouse)	Tnfsf8	NP_033429.1

Gene Ontology
Bibliography

Related articles in PubMed

Comparative genomic analysis of eutherian tumor necrosis factor ligand genes.
Premzl M
Immunogenetics68(2)125-32(2016 Feb)

A novel role of CD30/CD30 ligand signaling in the generation of long-lived memory CD8+ T cells.
Nishimura H, Yajima T, Muta H, Podack ER, Tani K, Yoshikai Y
Journal of immunology (Baltimore, Md. : 1950)175(7)4627-34(2005 Oct)

CD30L up-regulates CD30 and IL-4 expression by T cells.
Rossi FM, Degan M, Mazzocut-Zecchin L, Di Francia R, Aldinucci D, Pinto A, Gattei V
FEBS letters508(3)418-22(2001 Nov)

Phorbol esters and K+ up-regulate alpha-bungarotoxin binding sites in cultured chromaffin cells through a related mechanism.
Geertsen S, Trifaro JM, Quik M
Neuroscience letters148(1-2)207-10(1992 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Tnfsf8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tnfsf8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa16674	NM_001319033.1 Latest version!	Rattus norvegicus TNF superfamily member 8 (Tnfsf8), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa16675	XM_006238271.3 Latest version!	Rattus norvegicus tumor necrosis factor superfamily member 8 (Tnfsf8), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tnfsf8 ( NM_001319033.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001305962.1 Rattus norvegicus TNF superfamily member 8 (Tnfsf8), mRNA.

Price & Availability↑

CloneID	ORa16674
Clone ID Related Accession (Same CDS sequence)	NM_001319033.1
Accession Version	NM_001319033.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 714bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-31
Organism	Rattus norvegicus(Norway rat)
Product	tumor necrosis factor ligand superfamily member 8
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from LN874410.1. On or before Jan 20, 2016 this sequence version replaced XM_003749957.3, XM_001064723.5. ##Evidence-Data-START## Transcript exon combination :: LN874410.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689594, SAMEA2689603 [ECO:0000348] ##Evidence-Data-END##

ATGGAGCCAG GGCTGCAACA AGCACGCAGC CGTGGGGCCC CTTCCCCTGA CCCAGCCATG 
CAGGTGCCGC CCGGCTCGGC AGACAGCCTC TGGAGAAGCA CGAGGCCCTG GAGAACCCGC 
AGCTACTTCT ACCTCAGCAC CATCGCACTG GTGTGCCTTG TCGTGGCACT GGCAATCATT 
CTGGTCCTGG TAGTCCAGAA AAAGGACTCC ACTCCAAAAA CAACTGAGTC GGTCCCCCTT 
AAAGGAGGAA ATTGCTCAGA GGACCTCTTA TGTACCCTGA AAAGGACTCC ATCCAAGAAG 
TCATGGGCCT ACCTCCAAGT GTCGAAACAT CTCAACAGTG CCAAACTATC ATGGAACCAA 
GACGGTACCA TCCACGGACT CGTATACCAG GATGGGAACC TGGTGGTCCA ATTCCCAGGC 
TGGTACTTCA TCATTTGTCA ACTGCAATTT CTCGTGCAGT GCTCAAATCA TTCCATGGAC 
CTGACACTGC AGCTCGTCAT CAATTCCAAA ATCAAAAAGC AGGCACTGGT AACAGTGTGT 
GAGTCTGGAG TTCAAGGCAA GAACATCTAC CATAATCTCT CTCAGTTCTT GCTGCATTAC 
CTACAGGTCA ACTCTACCAT ATCTGTCCGG GTGGATAATT TCCAGTATGT GGATACAAAC 
ACTTTCCCTC TTGATAACGT GCTGTCCGTC TTCCTATATA GTAGCTCAGA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001305962.1
CDS	1..714
Translation	MEPGLQQARSRGAPSPDPAMQVPPGSADSLWRSTRPWRTRSYFYLSTIALVCLVVALAIILVLVVQKKDSTPKTTESVPLKGGNCSEDLLCTLKRTPSKKSWAYLQVSKHLNSAKLSWNQDGTIHGLVYQDGNLVVQFPGWYFIICQLQFLVQCSNHSMDLTLQLVINSKIKKQALVTVCESGVQGKNIYHNLSQFLLHYLQVNSTISVRVDNFQYVDTNTFPLDNVLSVFLYSSSD

Target ORF information:

RefSeq Version	NM_001319033.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus TNF superfamily member 8 (Tnfsf8), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001319033.1

ORF Insert Sequence:

ATGGAGCCAG GGCTGCAACA AGCACGCAGC CGTGGGGCCC CTTCCCCTGA CCCAGCCATG 
CAGGTGCCGC CCGGCTCGGC AGACAGCCTC TGGAGAAGCA CGAGGCCCTG GAGAACCCGC 
AGCTACTTCT ACCTCAGCAC CATCGCACTG GTGTGCCTTG TCGTGGCACT GGCAATCATT 
CTGGTCCTGG TAGTCCAGAA AAAGGACTCC ACTCCAAAAA CAACTGAGTC GGTCCCCCTT 
AAAGGAGGAA ATTGCTCAGA GGACCTCTTA TGTACCCTGA AAAGGACTCC ATCCAAGAAG 
TCATGGGCCT ACCTCCAAGT GTCGAAACAT CTCAACAGTG CCAAACTATC ATGGAACCAA 
GACGGTACCA TCCACGGACT CGTATACCAG GATGGGAACC TGGTGGTCCA ATTCCCAGGC 
TGGTACTTCA TCATTTGTCA ACTGCAATTT CTCGTGCAGT GCTCAAATCA TTCCATGGAC 
CTGACACTGC AGCTCGTCAT CAATTCCAAA ATCAAAAAGC AGGCACTGGT AACAGTGTGT 
GAGTCTGGAG TTCAAGGCAA GAACATCTAC CATAATCTCT CTCAGTTCTT GCTGCATTAC 
CTACAGGTCA ACTCTACCAT ATCTGTCCGG GTGGATAATT TCCAGTATGT GGATACAAAC 
ACTTTCCCTC TTGATAACGT GCTGTCCGTC TTCCTATATA GTAGCTCAGA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tnfsf8 ( XM_006238271.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006238333.1 Rattus norvegicus tumor necrosis factor superfamily member 8 (Tnfsf8), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa16675
Clone ID Related Accession (Same CDS sequence)	XM_006238271.3
Accession Version	XM_006238271.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 642bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	tumor necrosis factor ligand superfamily member 8 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006238271.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCCAG GGCTGCAACA AGCACGCAGC CGTGGGGCCC CTTCCCCTGA CCCAGCCATG 
CAGGTGCCGC CCGGCTCGGC AGACAGCCTC TGGAGAAGCA CGAGGCCCTG GAGAACCCGC 
AGCTACTTCT ACCTCAGCAC CATCGCACTG GTGTGCCTTG TCGTGGCACT GGCAATCATT 
CTGGTCCTGG TAGTCCAGAA AAAGGACTCC ACTCCAAAAA CAACTGAGTC GGTCCCCCTT 
AAAGGAGTGT CGAAACATCT CAACAGTGCC AAACTATCAT GGAACCAAGA CGGTACCATC 
CACGGACTCG TATACCAGGA TGGGAACCTG GTGGTCCAAT TCCCAGGCTG GTACTTCATC 
ATTTGTCAAC TGCAATTTCT CGTGCAGTGC TCAAATCATT CCATGGACCT GACACTGCAG 
CTCGTCATCA ATTCCAAAAT CAAAAAGCAG GCACTGGTAA CAGTGTGTGA GTCTGGAGTT 
CAAGGCAAGA ACATCTACCA TAATCTCTCT CAGTTCTTGC TGCATTACCT ACAGGTCAAC 
TCTACCATAT CTGTCCGGGT GGATAATTTC CAGTATGTGG ATACAAACAC TTTCCCTCTT 
GATAACGTGC TGTCCGTCTT CCTATATAGT AGCTCAGACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006238333.1
CDS	633..1274
Translation	MEPGLQQARSRGAPSPDPAMQVPPGSADSLWRSTRPWRTRSYFYLSTIALVCLVVALAIILVLVVQKKDSTPKTTESVPLKGVSKHLNSAKLSWNQDGTIHGLVYQDGNLVVQFPGWYFIICQLQFLVQCSNHSMDLTLQLVINSKIKKQALVTVCESGVQGKNIYHNLSQFLLHYLQVNSTISVRVDNFQYVDTNTFPLDNVLSVFLYSSSD

Target ORF information:

RefSeq Version	XM_006238271.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus tumor necrosis factor superfamily member 8 (Tnfsf8), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006238271.3

ORF Insert Sequence:

ATGGAGCCAG GGCTGCAACA AGCACGCAGC CGTGGGGCCC CTTCCCCTGA CCCAGCCATG 
CAGGTGCCGC CCGGCTCGGC AGACAGCCTC TGGAGAAGCA CGAGGCCCTG GAGAACCCGC 
AGCTACTTCT ACCTCAGCAC CATCGCACTG GTGTGCCTTG TCGTGGCACT GGCAATCATT 
CTGGTCCTGG TAGTCCAGAA AAAGGACTCC ACTCCAAAAA CAACTGAGTC GGTCCCCCTT 
AAAGGAGTGT CGAAACATCT CAACAGTGCC AAACTATCAT GGAACCAAGA CGGTACCATC 
CACGGACTCG TATACCAGGA TGGGAACCTG GTGGTCCAAT TCCCAGGCTG GTACTTCATC 
ATTTGTCAAC TGCAATTTCT CGTGCAGTGC TCAAATCATT CCATGGACCT GACACTGCAG 
CTCGTCATCA ATTCCAAAAT CAAAAAGCAG GCACTGGTAA CAGTGTGTGA GTCTGGAGTT 
CAAGGCAAGA ACATCTACCA TAATCTCTCT CAGTTCTTGC TGCATTACCT ACAGGTCAAC 
TCTACCATAT CTGTCCGGGT GGATAATTTC CAGTATGTGG ATACAAACAC TTTCCCTCTT 
GATAACGTGC TGTCCGTCTT CCTATATAGT AGCTCAGACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Comparative genomic analysis of eutherian tumor necrosis factor ligand genes.
Immunogenetics68(2)125-32(2016 Feb)
Premzl M

A novel role of CD30/CD30 ligand signaling in the generation of long-lived memory CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950)175(7)4627-34(2005 Oct)
Nishimura H,Yajima T,Muta H,Podack ER,Tani K,Yoshikai Y

CD30L up-regulates CD30 and IL-4 expression by T cells.
FEBS letters508(3)418-22(2001 Nov)
Rossi FM,Degan M,Mazzocut-Zecchin L,Di Francia R,Aldinucci D,Pinto A,Gattei V

Phorbol esters and K+ up-regulate alpha-bungarotoxin binding sites in cultured chromaffin cells through a related mechanism.
Neuroscience letters148(1-2)207-10(1992 Dec)
Geertsen S,Trifaro JM,Quik M