Mab21l2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Mab21l2
Entrez Gene ID	680102
Full Name	mab-21 like 2
General protein information	Preferred Names mab-21 like 2 Names protein mab-21-like 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q34

mRNA and Protein(s)

mRNA	Protein	Name
NM_001109391.1	NP_001102861.1	protein mab-21-like 2

Pathways from BioSystems

Homologies

	MAB21L2	XP_001082398.1
Xenopus tropicalis (tropical clawed frog)	mab21l2	NP_001096455.1
Anopheles gambiae (African malaria mosquito)	MB21L_ANOGA	XP_309230.3
Homo sapiens (human)	MAB21L2	NP_006430.1
Pan troglodytes (chimpanzee)	MAB21L2	XP_001151747.1
Bos taurus (cattle)	MAB21L2	XP_002694365.1
Mus musculus (house mouse)	Mab21l2	NP_035969.2
Canis lupus familiaris (dog)	MAB21L2	XP_867530.2
Rattus norvegicus (Norway rat)	Mab21l2	NP_001102861.1
Danio rerio (zebrafish)	mab21l2	NP_694507.1
Drosophila melanogaster (fruit fly)	CG4766	NP_572287.1

Gene Ontology
Bibliography

Related articles in PubMed

Mutations in MAB21L2 result in ocular Coloboma, microcornea and cataracts.
Deml B, Kariminejad A, Borujerdi RH, Muheisen S, Reis LM, Semina EV
PLoS genetics11(2)e1005002(2015)

Monoallelic and biallelic mutations in MAB21L2 cause a spectrum of major eye malformations.
Rainger J, Pehlivan D, Johansson S, Bengani H, Sanchez-Pulido L, Williamson KA, Ture M, Barker H, Rosendahl K, Spranger J, Horn D, Meynert A, Floyd JA, Prescott T, Anderson CA, Rainger JK, Karaca E, Gonzaga-Jauregui C, Jhangiani S, Muzny DM, Seawright A, Soares DC, Kharbanda M, Murday V, Finch A, , , Gibbs RA, van Heyningen V, Taylor MS, Yakut T, Knappskog PM, Hurles ME, Ponting CP, Lupski JR, Houge G, FitzPatrick DR
American journal of human genetics94(6)915-23(2014 Jun)

Requirement for Mab21l2 during development of murine retina and ventral body wall.
Yamada R, Mizutani-Koseki Y, Koseki H, Takahashi N
Developmental biology274(2)295-307(2004 Oct)

Two murine and human homologs of mab-21, a cell fate determination gene involved in Caenorhabditis elegans neural development.
Mariani M, Baldessari D, Francisconi S, Viggiano L, Rocchi M, Zappavigna V, Malgaretti N, Consalez GG
Human molecular genetics8(13)2397-406(1999 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Mab21l2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mab21l2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa41606	NM_001109391.1 Latest version!	Rattus norvegicus mab-21 like 2 (Mab21l2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Mab21l2 ( NM_001109391.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001102861.1 Rattus norvegicus mab-21 like 2 (Mab21l2), mRNA.

Price & Availability↑

CloneID	ORa41606
Clone ID Related Accession (Same CDS sequence)	NM_001109391.1
Accession Version	NM_001109391.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1080bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Rattus norvegicus(Norway rat)
Product	protein mab-21-like 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473976.2. On Oct 4, 2007 this sequence version replaced XM_001055031.1.

ATGATCGCCG CTCAGGCCAA GCTGGTTTAC CAGCTCAATA AATACTACAC CGAGCGCTGC 
CAGGCGCGCA AGGCTGCGAT CGCCAAGACC ATCCGAGAAG TCTGCAAGGT AGTGTCGGAT 
GTGCTGAAGG AAGTGGAAGT GCAGGAGCCG CGCTTCATCA GCTCTCTGAG CGAGATTGAC 
GCCCGCTACG AAGGGCTGGA AGTCATCTCT CCCACCGAGT TCGAGGTGGT ACTCTACCTC 
AACCAAATGG GAGTCTTCAA CTTCGTGGAC GACGGATCTC TGCCCGGCTG CGCAGTGCTC 
AAACTAAGCG ATGGGCGGAA GCGGAGCATG TCTCTTTGGG TCGAGTTCAT CACAGCGTCT 
GGTTACCTCT CTGCACGCAA GATCCGCTCG CGTTTCCAGA CATTGGTAGC CCAGGCGGTG 
GACAAGTGCA GCTACCGGGA CGTGGTCAAG ATGATCGCCG ACACTAGCGA GGTCAAGTTG 
CGCATCAGGG AGCGCTACGT GGTGCAAATC ACCCCAGCGT TCAAGTGCAC CGGGATCTGG 
CCTCGCAGCG CGGCACAGTG GCCTATGCCC CACATCCCCT GGCCCGGCCC CAATCGGGTG 
GCGGAGGTCA AGGCCGAAGG GTTCAACTTG CTCTCCAAGG AGTGCTACTC GCTGACTGGC 
AAGCAGAGCT CCGCAGAAAG CGACGCCTGG GTGCTGCAGT TCGGTGAGGC TGAGAACCGC 
TTGCTGATGG GCGGCTGTAG AAACAAGTGC CTCTCCGTGC TGAAGACGCT GCGGGACCGC 
CACCTGGAGC TGCCGGGCCA GCCGCTCAAT AACTACCACA TGAAGACGCT GCTGCTGTAC 
GAGTGCGAGA AACACCCGAG GGAAACGGAC TGGGACGAGG CTTGCCTGGG CGACCGTCTG 
AACGGCATCC TGCTACAGCT CATCTCTTGC CTGCAATGCC GCCGCTGCCC TCACTACTTT 
TTGCCCAACC TCGACCTCTT CCAGGGCAAG CCCCACTCGG CCCTGGAGAG CGCTGCCAAG 
CAGACCTGGA GATTGGCCAG GGAAATCCTC ACCAATCCCA AAAGCTTGGA CAAACTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001102861.1
CDS	961..2040
Translation	MIAAQAKLVYQLNKYYTERCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLSEIDARYEGLEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMIADTSEVKLRIRERYVVQITPAFKCTGIWPRSAAQWPMPHIPWPGPNRVAEVKAEGFNLLSKECYSLTGKQSSAESDAWVLQFGEAENRLLMGGCRNKCLSVLKTLRDRHLELPGQPLNNYHMKTLLLYECEKHPRETDWDEACLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALESAAKQTWRLAREILTNPKSLDKL

Target ORF information:

RefSeq Version	NM_001109391.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus mab-21 like 2 (Mab21l2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001109391.1

ORF Insert Sequence:

ATGATCGCCG CTCAGGCCAA GCTGGTTTAC CAGCTCAATA AATACTACAC CGAGCGCTGC 
CAGGCGCGCA AGGCTGCGAT CGCCAAGACC ATCCGAGAAG TCTGCAAGGT AGTGTCGGAT 
GTGCTGAAGG AAGTGGAAGT GCAGGAGCCG CGCTTCATCA GCTCTCTGAG CGAGATTGAC 
GCCCGCTACG AAGGGCTGGA AGTCATCTCT CCCACCGAGT TCGAGGTGGT ACTCTACCTC 
AACCAAATGG GAGTCTTCAA CTTCGTGGAC GACGGATCTC TGCCCGGCTG CGCAGTGCTC 
AAACTAAGCG ATGGGCGGAA GCGGAGCATG TCTCTTTGGG TCGAGTTCAT CACAGCGTCT 
GGTTACCTCT CTGCACGCAA GATCCGCTCG CGTTTCCAGA CATTGGTAGC CCAGGCGGTG 
GACAAGTGCA GCTACCGGGA CGTGGTCAAG ATGATCGCCG ACACTAGCGA GGTCAAGTTG 
CGCATCAGGG AGCGCTACGT GGTGCAAATC ACCCCAGCGT TCAAGTGCAC CGGGATCTGG 
CCTCGCAGCG CGGCACAGTG GCCTATGCCC CACATCCCCT GGCCCGGCCC CAATCGGGTG 
GCGGAGGTCA AGGCCGAAGG GTTCAACTTG CTCTCCAAGG AGTGCTACTC GCTGACTGGC 
AAGCAGAGCT CCGCAGAAAG CGACGCCTGG GTGCTGCAGT TCGGTGAGGC TGAGAACCGC 
TTGCTGATGG GCGGCTGTAG AAACAAGTGC CTCTCCGTGC TGAAGACGCT GCGGGACCGC 
CACCTGGAGC TGCCGGGCCA GCCGCTCAAT AACTACCACA TGAAGACGCT GCTGCTGTAC 
GAGTGCGAGA AACACCCGAG GGAAACGGAC TGGGACGAGG CTTGCCTGGG CGACCGTCTG 
AACGGCATCC TGCTACAGCT CATCTCTTGC CTGCAATGCC GCCGCTGCCC TCACTACTTT 
TTGCCCAACC TCGACCTCTT CCAGGGCAAG CCCCACTCGG CCCTGGAGAG CGCTGCCAAG 
CAGACCTGGA GATTGGCCAG GGAAATCCTC ACCAATCCCA AAAGCTTGGA CAAACTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mutations in MAB21L2 result in ocular Coloboma, microcornea and cataracts.
PLoS genetics11(2)e1005002(2015)
Deml B,Kariminejad A,Borujerdi RH,Muheisen S,Reis LM,Semina EV

Monoallelic and biallelic mutations in MAB21L2 cause a spectrum of major eye malformations.
American journal of human genetics94(6)915-23(2014 Jun)
Rainger J,Pehlivan D,Johansson S,Bengani H,Sanchez-Pulido L,Williamson KA,Ture M,Barker H,Rosendahl K,Spranger J,Horn D,Meynert A,Floyd JA,Prescott T,Anderson CA,Rainger JK,Karaca E,Gonzaga-Jauregui C,Jhangiani S,Muzny DM,Seawright A,Soares DC,Kharbanda M,Murday V,Finch A,,,Gibbs RA,van Heyningen V,Taylor MS,Yakut T,Knappskog PM,Hurles ME,Ponting CP,Lupski JR,Houge G,FitzPatrick DR

Requirement for Mab21l2 during development of murine retina and ventral body wall.
Developmental biology274(2)295-307(2004 Oct)
Yamada R,Mizutani-Koseki Y,Koseki H,Takahashi N

Two murine and human homologs of mab-21, a cell fate determination gene involved in Caenorhabditis elegans neural development.
Human molecular genetics8(13)2397-406(1999 Dec)
Mariani M,Baldessari D,Francisconi S,Viggiano L,Rocchi M,Zappavigna V,Malgaretti N,Consalez GG

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Mab21l2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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