Lemd3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lemd3
Entrez Gene ID	680066
Full Name	LEM domain containing 3
Synonyms	RGD1561001
General protein information	Preferred Names LEM domain containing 3 Names inner nuclear membrane protein Man1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 7 Map Location: 7q22

mRNA and Protein(s)

mRNA	Protein	Name
NM_001191000.1	NP_001177929.1	inner nuclear membrane protein Man1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	LEMD3	XP_005625712.1
Bos taurus (cattle)	LEMD3	NP_001179628.1
Homo sapiens (human)	LEMD3	NP_055134.2
Pan troglodytes (chimpanzee)	LEMD3	XP_509197.2
	LEMD3	XP_001116983.1
Mus musculus (house mouse)	Lemd3	NP_001074662.2
Rattus norvegicus (Norway rat)	Lemd3	NP_001177929.1
Gallus gallus (chicken)	LEMD3	XP_416073.3
Danio rerio (zebrafish)	lemd3	NP_001038329.1
Xenopus tropicalis (tropical clawed frog)	lemd3	NP_001136130.1

Gene Ontology
Bibliography

Related articles in PubMed

Buschke-Ollendorff syndrome associated with hypertrophic scar formation: a possible role for LEMD3 mutation.
Korekawa A, Nakano H, Toyomaki Y, Takiyoshi N, Rokunohe D, Akasaka E, Nakajima K, Sawamura D
The British journal of dermatology166(4)900-3(2012 Apr)

Buschke-Ollendorff syndrome with striking phenotypic variation resulting from a novel c.2203C>T nonsense mutation in LEMD3.
Yuste-Chaves M, Ca?ueto J, Santos-Briz ?, Ciria S, Gonz?lez-Sarmiento R, Unamuno P
Pediatric dermatology28(4)447-50(2011 Jul-Aug)

Buschke-Ollendorff syndrome: absence of LEMD3 mutation in an affected family.
Yadegari M, Whyte MP, Mumm S, Phelps RG, Shanske A, Totty WG, Cohen SR
Archives of dermatology146(1)63-8(2010 Jan)

Overlapping functions of nuclear envelope proteins NET25 (Lem2) and emerin in regulation of extracellular signal-regulated kinase signaling in myoblast differentiation.
Huber MD, Guan T, Gerace L
Molecular and cellular biology29(21)5718-28(2009 Nov)

Novel and recurrent germline LEMD3 mutations causing Buschke-Ollendorff syndrome and osteopoikilosis but not isolated melorheostosis.
Zhang Y, Castori M, Ferranti G, Paradisi M, Wordsworth BP
Clinical genetics75(6)556-61(2009 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Lemd3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lemd3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa06799	NM_001191000.1 Latest version!	Rattus norvegicus LEM domain containing 3 (Lemd3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$475.30 $679.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lemd3 ( NM_001191000.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001177929.1 Rattus norvegicus LEM domain containing 3 (Lemd3), mRNA.

Price & Availability↑

CloneID	ORa06799
Clone ID Related Accession (Same CDS sequence)	NM_001191000.1
Accession Version	NM_001191000.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2745bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-31
Organism	Rattus norvegicus(Norway rat)
Product	inner nuclear membrane protein Man1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AABR07057253.1 and AABR07057252.1. On Jul 8, 2010 this sequence version replaced XM_001055542.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN01906350 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGCGG CGGCGGCTAC GGCGGCTTCG GCGCCTCAGC AGCTCTCAGA TGAGGAGCTT 
TTCTCTCAGC TCCGCCGTTA CGGCTTGTCT CCGGGTCCCG TGACAGAGAG CACTCGGCCG 
GTCTACCTCA AGAAGCTGAA GAAGCTTCGC GAGGAAGAGC AGCAGCAGCA GCAGCACCGG 
GCGGGGGGCC GCGGCAACAA GACGCGGAAC AGTAATAACA ATAACACGGC GGCCGCGGCG 
AGTGTAGCCG CGGCACCGGC GGGGATGGGG GTCCGGCCGG GCTCGGGGGA CTTCGCGTAC 
TTACGGACTC CCGCGGGCCT CGGCCGCCTG TCGGCCTCCG CTCCGGAGAG CCCCGCGGGA 
GGCTCCGGGG TCGCGGCGGC CGTCCCCGCG GCGGGCAGCA AAGTGCTGCT GGGCTTTAGC 
TCCGACGAGT CGGACGTGGA GGCCAGTCCG CGGGAGCAGG CGGGCGGCGG CGGAGCGCGG 
AGGGACCGGG CTGCTCTCCA GTACCGCGGG CTCAAAGCGC CACCGGCGCC CCCGGTCGCG 
GGTGAGGCGA CGAGCGGCAA CTCGGCCGAG CGGAGGAAGC CCCACTCGTG GTGGGGGGCG 
CGGAGGCCGG TGGGCCCCGA GCCGCAGCTC CCGTCGGGGA GCGACGGGGC CGCGGAGGAC 
GTGGACGAGG AGGTAGCGGA CGGTGAGGAC AGGGACCCGG AGGCGGAGGA GCCGCTGTGG 
GGCAGCCGAG CCGTGAACGG CAGCCGGCTT CTCCCCTACA GCTGCCGGGA GCATTACTCG 
GACTCGGAGG AGGAGGACGA CGGCGGCGAC GTGGCCTCGG CTAGACAGGT ATTAAAGGAC 
GACTCCCTTT CCCGGCATCG ACCCAGACGG AGCCATAGTA AGCCGTTCTC CGCGCTGACT 
GCTAAATCTG GCGGCAGCCG GCAGGAGACT TCAGTTCAGG GAGGGGGAGG ACTCGCGATG 
AATGACAGGG CGGCGGCTGC GGGGAGTCTA GACAGGAGCC GAAACCTCGA GGAGGCGGCG 
GCCGAGCCGG GAGGCGGAGG AGGAGGAGGA GGGTGCGATC AAGTGGACTC CATTCCTCGA 
TACCGTGCTG GCGCGAAGAA GCTGGCACCG CTCCTGTCGC CGCCGAGTCC CGACGTGGAC 
TCAACCTTGG AGTCGCCCAC AGGGCCCCTC AAAACCAATA ATCACATAGG CGGCGGCGGG 
GCCTTCGGCG TGGATTCCCC CAGTCTGTAT GCCAACAGCA TCCCTCCCGG AGCGGCCGCG 
ACCGCCCCTG GTTCACTCAG GATCAACCAC GCCAACCATA CGGGCTCCAA TCATACCTAC 
CTGAAAAACG CCTACAGCAA GCCAAAGCTC TGCGAGCCCG AAGAGGAACT TCTCCAGCAG 
TTTAAACGTG AGGAGGTGTC TCCGACGGGG AGTTTCAGTG CTCACTACCT GTCGATGTTC 
CTCCTAACTG CAGCCTGCTT ATTTTTCCTA ATATTGGGAC TGACTTACCT AGGAATGAGA 
GGGACAGGAG TACCCGAGGA CGGAAGACTC TTAAAAAACC CCTTTGATGA AACATTTGGA 
AAAATACAAG CAAGTGAAAA AAATCTTATG ATGAGCACAT TATACAAACT TCATGATCGA 
TTGGCTCAGA TTGCAGGAGA TCATGAATGT GGCCGTTCCA GCCAAAGGAT GCTTTCTGTC 
CAAGAAGCAG CTGCATATTT AAAAGATTTA GGTCCTGAGT ATGAAGATGT ATTTAACACT 
TCACTGCTGT GGATTTTTAA AAATGGGAAA GATGTTGGAA TAAGGTGTGT TGGTTATGGA 
CCTGAGGAAG ACCTGACAAA CATAACCGAT GTGCAGTTTT TACAGTCCAC CAGACCACAG 
ATGCCGTTCT GGTGCCGTTT CCGCCGTGCT TTCATTACCG TGACCCATAG GTTACTGCTG 
TTGTGCTTAG GTGTAGTCCT GGTCTGTGCT GTCCTCCGTT ATATGAGATA CCGCTGGACG 
AAGGAGGAAG AAGAGACAAG GCAGATGTAT GACATGGTGG TGAAGATCAT AGATGTTTTA 
CGAAGTCATA ATGAAGCCTG TCAGGAAACT AAGGACTTAC AGCCTTACAT GCCTATTCCA 
CATGTTCGAG ATTCCCTAAT ACAGCCCCAG GACAGGAAAA AGATGAAGAA AGTGTGGGAA 
AGAGCTGTTG ACTTCCTTGC TGCTAATGAG TCTAGAGTGC GAACAGAGAC TCGAAGAGTG 
GGTGGTGCAG ACTTCGTAGT CTGGCGGTGG GTCCAGCCTT CTGCATCTTG TGACAAGACG 
TCAGTCATAC CCTCTAAAGT ATGGCAAGGT CAAGCATTTC ATTTAGATAG AAGAAATTCA 
CCACCAAATA GTTTGACGCC ATGTTTAAAG ATTCGGAATA TGTTTGACCC AGTTATGGAA 
ATAGGAGATC ACTGGCATCT GGCAATTCAA GAAGCAATTT TAGAGAAGTG CAGCGATAAC 
GACGGCATTG TTCATATCGC GGTAGACAGG AACTCCCGTG AGGGCTGCGT GTATGTTAAG 
TGTCTGTCTC CGGGACATGC TGGGAAGGCT TTTAAAGCCC TGCACGGCTC CTGGTTCGAT 
GGAAAATTGG TAACAGTAAA ATACTTACGA CTAGATAGAT ACCACCACCG CTTCCCCCAG 
GCTCTTACGT GCAGCACTCC CTTGAAGCCA TCAGACAAAC ACATGAACTC CATGTCTCAC 
CTGCGCCTGC GAACTGGCCT AGCTAATTCT CAAGGAAGTT CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001177929.1
CDS	1..2745
Translation	MAAAAATAASAPQQLSDEELFSQLRRYGLSPGPVTESTRPVYLKKLKKLREEEQQQQQHRAGGRGNKTRNSNNNNTAAAASVAAAPAGMGVRPGSGDFAYLRTPAGLGRLSASAPESPAGGSGVAAAVPAAGSKVLLGFSSDESDVEASPREQAGGGGARRDRAALQYRGLKAPPAPPVAGEATSGNSAERRKPHSWWGARRPVGPEPQLPSGSDGAAEDVDEEVADGEDRDPEAEEPLWGSRAVNGSRLLPYSCREHYSDSEEEDDGGDVASARQVLKDDSLSRHRPRRSHSKPFSALTAKSGGSRQETSVQGGGGLAMNDRAAAAGSLDRSRNLEEAAAEPGGGGGGGGCDQVDSIPRYRAGAKKLAPLLSPPSPDVDSTLESPTGPLKTNNHIGGGGAFGVDSPSLYANSIPPGAAATAPGSLRINHANHTGSNHTYLKNAYSKPKLCEPEEELLQQFKREEVSPTGSFSAHYLSMFLLTAACLFFLILGLTYLGMRGTGVPEDGRLLKNPFDETFGKIQASEKNLMMSTLYKLHDRLAQIAGDHECGRSSQRMLSVQEAAAYLKDLGPEYEDVFNTSLLWIFKNGKDVGIRCVGYGPEEDLTNITDVQFLQSTRPQMPFWCRFRRAFITVTHRLLLLCLGVVLVCAVLRYMRYRWTKEEEETRQMYDMVVKIIDVLRSHNEACQETKDLQPYMPIPHVRDSLIQPQDRKKMKKVWERAVDFLAANESRVRTETRRVGGADFVVWRWVQPSASCDKTSVIPSKVWQGQAFHLDRRNSPPNSLTPCLKIRNMFDPVMEIGDHWHLAIQEAILEKCSDNDGIVHIAVDRNSREGCVYVKCLSPGHAGKAFKALHGSWFDGKLVTVKYLRLDRYHHRFPQALTCSTPLKPSDKHMNSMSHLRLRTGLANSQGSS

Target ORF information:

RefSeq Version	NM_001191000.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus LEM domain containing 3 (Lemd3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001191000.1

ORF Insert Sequence:

ATGGCGGCGG CGGCGGCTAC GGCGGCTTCG GCGCCTCAGC AGCTCTCAGA TGAGGAGCTT 
TTCTCTCAGC TCCGCCGTTA CGGCTTGTCT CCGGGTCCCG TGACAGAGAG CACTCGGCCG 
GTCTACCTCA AGAAGCTGAA GAAGCTTCGC GAGGAAGAGC AGCAGCAGCA GCAGCACCGG 
GCGGGGGGCC GCGGCAACAA GACGCGGAAC AGTAATAACA ATAACACGGC GGCCGCGGCG 
AGTGTAGCCG CGGCACCGGC GGGGATGGGG GTCCGGCCGG GCTCGGGGGA CTTCGCGTAC 
TTACGGACTC CCGCGGGCCT CGGCCGCCTG TCGGCCTCCG CTCCGGAGAG CCCCGCGGGA 
GGCTCCGGGG TCGCGGCGGC CGTCCCCGCG GCGGGCAGCA AAGTGCTGCT GGGCTTTAGC 
TCCGACGAGT CGGACGTGGA GGCCAGTCCG CGGGAGCAGG CGGGCGGCGG CGGAGCGCGG 
AGGGACCGGG CTGCTCTCCA GTACCGCGGG CTCAAAGCGC CACCGGCGCC CCCGGTCGCG 
GGTGAGGCGA CGAGCGGCAA CTCGGCCGAG CGGAGGAAGC CCCACTCGTG GTGGGGGGCG 
CGGAGGCCGG TGGGCCCCGA GCCGCAGCTC CCGTCGGGGA GCGACGGGGC CGCGGAGGAC 
GTGGACGAGG AGGTAGCGGA CGGTGAGGAC AGGGACCCGG AGGCGGAGGA GCCGCTGTGG 
GGCAGCCGAG CCGTGAACGG CAGCCGGCTT CTCCCCTACA GCTGCCGGGA GCATTACTCG 
GACTCGGAGG AGGAGGACGA CGGCGGCGAC GTGGCCTCGG CTAGACAGGT ATTAAAGGAC 
GACTCCCTTT CCCGGCATCG ACCCAGACGG AGCCATAGTA AGCCGTTCTC CGCGCTGACT 
GCTAAATCTG GCGGCAGCCG GCAGGAGACT TCAGTTCAGG GAGGGGGAGG ACTCGCGATG 
AATGACAGGG CGGCGGCTGC GGGGAGTCTA GACAGGAGCC GAAACCTCGA GGAGGCGGCG 
GCCGAGCCGG GAGGCGGAGG AGGAGGAGGA GGGTGCGATC AAGTGGACTC CATTCCTCGA 
TACCGTGCTG GCGCGAAGAA GCTGGCACCG CTCCTGTCGC CGCCGAGTCC CGACGTGGAC 
TCAACCTTGG AGTCGCCCAC AGGGCCCCTC AAAACCAATA ATCACATAGG CGGCGGCGGG 
GCCTTCGGCG TGGATTCCCC CAGTCTGTAT GCCAACAGCA TCCCTCCCGG AGCGGCCGCG 
ACCGCCCCTG GTTCACTCAG GATCAACCAC GCCAACCATA CGGGCTCCAA TCATACCTAC 
CTGAAAAACG CCTACAGCAA GCCAAAGCTC TGCGAGCCCG AAGAGGAACT TCTCCAGCAG 
TTTAAACGTG AGGAGGTGTC TCCGACGGGG AGTTTCAGTG CTCACTACCT GTCGATGTTC 
CTCCTAACTG CAGCCTGCTT ATTTTTCCTA ATATTGGGAC TGACTTACCT AGGAATGAGA 
GGGACAGGAG TACCCGAGGA CGGAAGACTC TTAAAAAACC CCTTTGATGA AACATTTGGA 
AAAATACAAG CAAGTGAAAA AAATCTTATG ATGAGCACAT TATACAAACT TCATGATCGA 
TTGGCTCAGA TTGCAGGAGA TCATGAATGT GGCCGTTCCA GCCAAAGGAT GCTTTCTGTC 
CAAGAAGCAG CTGCATATTT AAAAGATTTA GGTCCTGAGT ATGAAGATGT ATTTAACACT 
TCACTGCTGT GGATTTTTAA AAATGGGAAA GATGTTGGAA TAAGGTGTGT TGGTTATGGA 
CCTGAGGAAG ACCTGACAAA CATAACCGAT GTGCAGTTTT TACAGTCCAC CAGACCACAG 
ATGCCGTTCT GGTGCCGTTT CCGCCGTGCT TTCATTACCG TGACCCATAG GTTACTGCTG 
TTGTGCTTAG GTGTAGTCCT GGTCTGTGCT GTCCTCCGTT ATATGAGATA CCGCTGGACG 
AAGGAGGAAG AAGAGACAAG GCAGATGTAT GACATGGTGG TGAAGATCAT AGATGTTTTA 
CGAAGTCATA ATGAAGCCTG TCAGGAAACT AAGGACTTAC AGCCTTACAT GCCTATTCCA 
CATGTTCGAG ATTCCCTAAT ACAGCCCCAG GACAGGAAAA AGATGAAGAA AGTGTGGGAA 
AGAGCTGTTG ACTTCCTTGC TGCTAATGAG TCTAGAGTGC GAACAGAGAC TCGAAGAGTG 
GGTGGTGCAG ACTTCGTAGT CTGGCGGTGG GTCCAGCCTT CTGCATCTTG TGACAAGACG 
TCAGTCATAC CCTCTAAAGT ATGGCAAGGT CAAGCATTTC ATTTAGATAG AAGAAATTCA 
CCACCAAATA GTTTGACGCC ATGTTTAAAG ATTCGGAATA TGTTTGACCC AGTTATGGAA 
ATAGGAGATC ACTGGCATCT GGCAATTCAA GAAGCAATTT TAGAGAAGTG CAGCGATAAC 
GACGGCATTG TTCATATCGC GGTAGACAGG AACTCCCGTG AGGGCTGCGT GTATGTTAAG 
TGTCTGTCTC CGGGACATGC TGGGAAGGCT TTTAAAGCCC TGCACGGCTC CTGGTTCGAT 
GGAAAATTGG TAACAGTAAA ATACTTACGA CTAGATAGAT ACCACCACCG CTTCCCCCAG 
GCTCTTACGT GCAGCACTCC CTTGAAGCCA TCAGACAAAC ACATGAACTC CATGTCTCAC 
CTGCGCCTGC GAACTGGCCT AGCTAATTCT CAAGGAAGTT CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Buschke-Ollendorff syndrome associated with hypertrophic scar formation: a possible role for LEMD3 mutation.
The British journal of dermatology166(4)900-3(2012 Apr)
Korekawa A,Nakano H,Toyomaki Y,Takiyoshi N,Rokunohe D,Akasaka E,Nakajima K,Sawamura D

Buschke-Ollendorff syndrome with striking phenotypic variation resulting from a novel c.2203C>T nonsense mutation in LEMD3.
Pediatric dermatology28(4)447-50(2011 Jul-Aug)
Yuste-Chaves M,Ca?ueto J,Santos-Briz ?,Ciria S,Gonz?lez-Sarmiento R,Unamuno P

Buschke-Ollendorff syndrome: absence of LEMD3 mutation in an affected family.
Archives of dermatology146(1)63-8(2010 Jan)
Yadegari M,Whyte MP,Mumm S,Phelps RG,Shanske A,Totty WG,Cohen SR

Overlapping functions of nuclear envelope proteins NET25 (Lem2) and emerin in regulation of extracellular signal-regulated kinase signaling in myoblast differentiation.
Molecular and cellular biology29(21)5718-28(2009 Nov)
Huber MD,Guan T,Gerace L

Novel and recurrent germline LEMD3 mutations causing Buschke-Ollendorff syndrome and osteopoikilosis but not isolated melorheostosis.
Clinical genetics75(6)556-61(2009 Jun)
Zhang Y,Castori M,Ferranti G,Paradisi M,Wordsworth BP

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

Lemd3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報