Adgrl1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Adgrl1
Entrez Gene ID	65096
Full Name	adhesion G protein-coupled receptor L1
Synonyms	CL1BA,Lphn1
General protein information	Preferred Names adhesion G protein-coupled receptor L1 Names adhesion G protein-coupled receptor L1 CIRL-1 calcium-independent alpha-latrotoxin receptor 1 latrophilin-1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 19 Map Location: 19q11
Summary	G protein-coupled receptor for alpha-Latrotoxin [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_022962.1	NP_075251.1	adhesion G protein-coupled receptor L1 precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	LPHN1	XP_003953443.1
Xenopus tropicalis (tropical clawed frog)	lphn1	XP_004918935.1
Canis lupus familiaris (dog)	LPHN1	XP_005632850.1
Rattus norvegicus (Norway rat)	Lphn1	NP_075251.1
Homo sapiens (human)	LPHN1	NP_001008701.1
Bos taurus (cattle)	LPHN1	NP_001107200.1
Mus musculus (house mouse)	Lphn1	NP_851382.2
Danio rerio (zebrafish)	LOC562531	XP_691000.6
	LPHN1	XP_002808220.1

Gene Ontology
Bibliography

Related articles in PubMed

Calsyntenins function as synaptogenic adhesion molecules in concert with neurexins.
Um JW, Pramanik G, Ko JS, Song MY, Lee D, Kim H, Park KS, S?dhof TC, Tabuchi K, Ko J
Cell reports6(6)1096-1109(2014 Mar)

High affinity neurexin binding to cell adhesion G-protein-coupled receptor CIRL1/latrophilin-1 produces an intercellular adhesion complex.
Boucard AA, Ko J, S?dhof TC
The Journal of biological chemistry287(12)9399-413(2012 Mar)

Latrophilin 1 and its endogenous ligand Lasso/teneurin-2 form a high-affinity transsynaptic receptor pair with signaling capabilities.
Silva JP, Lelianova VG, Ermolyuk YS, Vysokov N, Hitchen PG, Berninghausen O, Rahman MA, Zangrandi A, Fidalgo S, Tonevitsky AG, Dell A, Volynski KE, Ushkaryov YA
Proceedings of the National Academy of Sciences of the United States of America108(29)12113-8(2011 Jul)

Dissociation of the subunits of the calcium-independent receptor of alpha-latrotoxin as a result of two-step proteolysis.
Krasnoperov V, Deyev IE, Serova OV, Xu C, Lu Y, Buryanovsky L, Gabibov AG, Neubert TA, Petrenko AG
Biochemistry48(14)3230-8(2009 Apr)

Post-translational proteolytic processing of the calcium-independent receptor of alpha-latrotoxin (CIRL), a natural chimera of the cell adhesion protein and the G protein-coupled receptor. Role of the G protein-coupled receptor proteolysis site (GPS) motif.
Krasnoperov V, Lu Y, Buryanovsky L, Neubert TA, Ichtchenko K, Petrenko AG
The Journal of biological chemistry277(48)46518-26(2002 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Neurexin 1 binding to latrophilin-1 produces a stable intercellular adhesion complex.
Title: High affinity neurexin binding to cell adhesion G-protein-coupled receptor CIRL1/latrophilin-1 produces an intercellular adhesion complex.

Latrophilin 1 and its endogenous ligand Lasso/teneurin-2 form a high-affinity transsynaptic receptor pair with signaling capabilities.
Title: Latrophilin 1 and its endogenous ligand Lasso/teneurin-2 form a high-affinity transsynaptic receptor pair with signaling capabilities.

further cleavage of CIRL by a second protease results in a soluble form of CIRL
Title: Dissociation of the subunits of the calcium-independent receptor of alpha-latrotoxin as a result of two-step proteolysis.

The following Adgrl1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Adgrl1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa06552	NM_022962.1 Latest version!	Rattus norvegicus adhesion G protein-coupled receptor L1 (Adgrl1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$1084.30 $1549.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Adgrl1 ( NM_022962.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_075251.1 Rattus norvegicus adhesion G protein-coupled receptor L1 (Adgrl1), mRNA.

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CloneID	ORa06552
Clone ID Related Accession (Same CDS sequence)	NM_022962.1
Accession Version	NM_022962.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4416bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-22
Organism	Rattus norvegicus(Norway rat)
Product	adhesion G protein-coupled receptor L1 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF081146.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF081146.1, U72487.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGCCCGCT TGGCTGCAGC ACTCTGGAGT CTCTGTGTGA CGACTGTCCT CGTCACCTCT 
GCTACCCAAG GCCTGAGCCG GGCTGGACTC CCATTTGGAT TGATGCGCCG GGAGCTAGCA 
TGCGAAGGCT ACCCCATTGA GCTGCGGTGC CCGGGCAGTG ACGTCATCAT GGTGGAGAAT 
GCAAACTATG GGCGCACAGA TGACAAGATC TGCGATGCCG ACCCTTTTCA GATGGAGAAC 
GTGCAGTGCT ACCTGCCTGA CGCCTTCAAA ATCATGTCAC AGAGATGTAA TAACCGAACC 
CAGTGTGTGG TGGTGGCCGG CTCTGACGCC TTTCCTGACC CCTGTCCTGG AACCTACAAG 
TACCTGGAGG TGCAGTACGA CTGTGTCCCT TACAAAGTGG AGCAGAAAGT CTTCGTGTGC 
CCAGGGACAC TGCAGAAGGT GCTGGAGCCC ACCTCCACAC ATGAATCGGA GCACCAGTCT 
GGCGCATGGT GCAAGGACCC ACTGCAGGCA GGTGACCGTA TCTACGTTAT GCCCTGGATC 
CCCTACCGCA CGGACACACT GACCGAGTAT GCTTCCTGGG AGGACTATGT GGCTGCACGC 
CACACCACCA CGTACAGACT GCCCAACCGT GTAGATGGCA CTGGCTTTGT GGTATATGAT 
GGTGCCGTCT TCTATAACAA GGAACGTACT CGCAACATTG TCAAATATGA CCTGCGGACC 
CGCATCAAGA GCGGAGAAAC AGTCATAAAC ACAGCCAACT ACCACGACAC CTCACCTTAT 
CGCTGGGGAG GCAAAACCGA CATTGACCTG GCAGTGGATG AGAACGGGCT GTGGGTCATC 
TATGCCACCG AGGGGAACAA CGGGCGTCTG GTGGTGAGCC AGCTCAACCC CTACACACTG 
CGTTTCGAGG GCACCTGGGA AACAGGCTAT GACAAGCGCT CAGCCTCCAA TGCCTTCATG 
GTGTGTGGTG TCCTCTATGT GCTGCGCTCT GTTTATGTGG ATGACGACAG TGAGGCAGCA 
GGCAACCGCG TGGACTATGC CTTTAACACC AATGCAAACC GAGAGGAGCC CGTCAGTCTC 
GCCTTCCCCA ACCCCTACCA GTTTGTATCT TCTGTTGACT ACAATCCCCG GGACAACCAG 
CTGTATGTGT GGAACAACTA TTTCGTGGTG CGCTACAGCC TGGAGTTTGG ACCCCCAGAT 
CCCAGTGCTG GCCCAGCCAC TTCCCCACCT CTCAGTACCA CCACCACAGC TCGGCCTACG 
CCCCTCACCA GCACAGCCTC ACCTGCAGCC ACCACTCCAC TCCGCCGGGC GCCCCTCACC 
ACGCACCCAG TAGGTGCCAT CAACCAGCTG GGACCTGACC TGCCTCCAGC CACAGCCCCA 
GCACCCAGTA CCCGGCGGCC TCCAGCCCCC AATCTGCATG TGTCCCCTGA GCTCTTCTGT 
GAACCCCGAG AGGTCCGGCG GGTCCAGTGG CCAGCTACCC AGCAGGGTAT GCTGGTAGAG 
AGACCTTGCC CCAAGGGAAC TCGAGGAATT GCCTCGTTCC AGTGCCTCCC AGCTCTGGGG 
CTCTGGAATC CTCGGGGCCC TGACCTCAGC AACTGCACTT CCCCCTGGGT CAACCAAGTC 
GCCCAGAAGA TCAAGAGTGG AGAGAATGCA GCCAACATTG CTAGTGAGCT GGCCCGCCAC 
ACGCGGGGCT CCATCTATGC TGGGGACGTG TCCTCATCGG TGAAGCTGAT GGAGCAACTG 
CTAGATATCC TGGATGCCCA GCTCCAGGCC CTACGGCCCA TTGAACGAGA GTCAGCTGGC 
AAGAACTACA ATAAGATGCA CAAGCGAGAG AGAACCTGCA AGGACTATAT CAAGGCTGTG 
GTGGAGACAG TGGACAACCT GCTTCGGCCA GAGGCACTTG AGTCATGGAA AGACATGAAT 
GCCACCGAAC AGGTCCATAC GGCCACCATG CTCCTAGATG TCTTAGAGGA GGGTGCCTTC 
CTGCTGGCCG ACAATGTCAG AGAACCTGCT CGCTTCTTGG CTGCCAAGCA GAATGTGGTC 
CTGGAGGTCA CTGTCCTGAG CACAGAGGGT CAAGTGCAGG AGTTGGTGTT CCCCCAGGAG 
TATGCCAGTG AGAGCTCCAT TCAGCTGTCC GCCAACACCA TCAAGCAGAA CAGCCGCAAT 
GGTGTGGTGA AGGTTGTCTT CATTCTCTAC AACAACCTGG GCCTCTTCTT GTCCACGGAG 
AATGCCACAG TGAAGCTGGC AGGTGAGGCA GGGACCGGTG GCCCTGGAGG TGCCTCCCTG 
GTGGTTAACT CACAGGTCAT CGCAGCATCC ATCAATAAGG AGTCCAGCCG TGTCTTCCTC 
ATGGACCCTG TCATCTTTAC TGTGGCCCAC TTGGAGGCCA AGAACCACTT CAATGCAAAC 
TGCTCCTTCT GGAACTACTC AGAGCGCTCC ATGCTGGGCT ACTGGTCAAC CCAGGGCTGC 
CGACTGGTGG AGTCCAATAA GACCCATACC ACATGTGCCT GCAGCCACCT CACCAACTTC 
GCAGTGCTCA TGGCTCACCG AGAGATCTAC CAAGGCCGTA TTAATGAGCT GTTGCTGTCA 
GTCATCACCT GGGTTGGCAT TGTCATCTCC CTGGTCTGTC TGGCTATCTG CATCTCCACC 
TTCTGCTTCC TGCGGGGCCT GCAGACCGAC CGCAACACCA TCCACAAGAA CCTGTGCATC 
AACCTCTTCC TTGCAGAGCT GCTCTTCCTG GTTGGAATAG ACAAAACTCA GTATGAGGTC 
GCCTGCCCTA TCTTTGCGGG CCTGCTGCAC TACTTCTTCC TGGCCGCCTT CTCCTGGCTG 
TGCCTAGAGG GCGTGCACCT CTACCTCCTG CTGGTCGAGG TGTTCGAGAG CGAATATTCA 
CGCACCAAGT ACTATTACCT GGGCGGCTAC TGCTTCCCAG CCCTGGTGGT AGGCATCGCA 
GCCGCCATTG ACTACCGAAG CTACGGCACT GAGAAGGCCT GCTGGCTGAG GGTGGATAAC 
TATTTCATCT GGAGCTTCAT TGGGCCCGTC TCCTTTGTTA TTGTGGTGAA CCTGGTGTTC 
CTCATGGTGA CCCTGCACAA GATGATCCGA AGCTCATCCG TGCTCAAGCC TGACTCCAGC 
CGCCTTGACA ACATCAAGTC CTGGGCGCTG GGTGCCATTG CACTGCTCTT CCTGCTGGGC 
CTCACCTGGG CTTTCGGCCT CCTCTTCATC AACAAGGAGT CAGTAGTAAT GGCTTACCTC 
TTCACAACCT TCAACGCCTT CCAGGGGGTC TTCATCTTTG TCTTTCACTG CGCCTTACAG 
AAAAAGGTGC ACAAGGAGTA CAGCAAGTGC CTGCGTCACT CCTACTGCTG CATTCGCTCC 
CCACCTGGGG GGGCTCACGG CTCCCTTAAG ACCTCAGCCA TGCGAAGTAA CACCCGCTAC 
TACACAGGGA CCCAGAGCCG AATCCGGAGG ATGTGGAATG ACACCGTGAG GAAGCAGACA 
GAGTCGTCCT TTATGGCAGG GGACATCAAC AGCACCCCCA CCCTGAACCG AGGTACCATG 
GGGAACCACC TACTGACCAA CCCTGTGCTA CAGCCCCGTG GGGGCACTAG CCCATACAAT 
ACACTCATTG CAGAGTCTGT GGGCTTCAAT CCCTCCTCGC CCCCAGTCTT CAACTCCCCA 
GGAAGCTACA GGGAACCTAA GCACCCCTTG GGCGGCCGGG AAGCCTGTGG CATGGACACA 
CTGCCCCTTA ATGGCAACTT CAACAACAGC TACTCCTTGC GAAGTGGTGA TTTCCCTCCG 
GGGGATGGGG GTCCTGAGCC ACCCCGAGGC CGAAACCTAG CGGATGCTGC GGCCTTTGAG 
AAGATGATCA TCTCAGAGCT GGTGCACAAC AACCTTCGGG GGGCCAGTGG GGGCGCCAAA 
GGTCCTCCAC CAGAGCCTCC TGTGCCACCC GTGCCAGGAG TCAGTGAGGA CGAGGCTGGT 
GGGCCTGGGG GTGCTGACCG GGCTGAGATT GAACTTCTCT ACAAGGCCCT GGAGGAGCCA 
CTGCTGCTGC CCCGGGCCCA GTCGGTGCTG TACCAGAGTG ATCTGGATGA GTCGGAGAGC 
TGTACGGCAG AGGATGGGGC CACCAGCCGG CCCCTCTCCT CCCCTCCCGG CCGGGACTCC 
CTCTATGCCA GCGGGGCCAA CCTGCGGGAC TCGCCCTCCT ACCCGGACAG CAGCCCCGAA 
GGGCCTAATG AGGCCCTGCC CCCTCCCCCA CCTGCTCCCC CTGGGCCCCC AGAAATCTAC 
TACACCTCTC GCCCGCCGGC CCTGGTGGCT CGGAATCCCC TACAGGGCTA CTACCAGGTG 
CGGCGGCCCA GCCATGAGGG CTACCTGGCA GCCCCCAGCC TTGAGGGGCC AGGGCCCGAT 
GGGGATGGGC AAATGCAGTT GGTCACTAGT CTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_075251.1
CDS	283..4698
Translation	MARLAAALWSLCVTTVLVTSATQGLSRAGLPFGLMRRELACEGYPIELRCPGSDVIMVENANYGRTDDKICDADPFQMENVQCYLPDAFKIMSQRCNNRTQCVVVAGSDAFPDPCPGTYKYLEVQYDCVPYKVEQKVFVCPGTLQKVLEPTSTHESEHQSGAWCKDPLQAGDRIYVMPWIPYRTDTLTEYASWEDYVAARHTTTYRLPNRVDGTGFVVYDGAVFYNKERTRNIVKYDLRTRIKSGETVINTANYHDTSPYRWGGKTDIDLAVDENGLWVIYATEGNNGRLVVSQLNPYTLRFEGTWETGYDKRSASNAFMVCGVLYVLRSVYVDDDSEAAGNRVDYAFNTNANREEPVSLAFPNPYQFVSSVDYNPRDNQLYVWNNYFVVRYSLEFGPPDPSAGPATSPPLSTTTTARPTPLTSTASPAATTPLRRAPLTTHPVGAINQLGPDLPPATAPAPSTRRPPAPNLHVSPELFCEPREVRRVQWPATQQGMLVERPCPKGTRGIASFQCLPALGLWNPRGPDLSNCTSPWVNQVAQKIKSGENAANIASELARHTRGSIYAGDVSSSVKLMEQLLDILDAQLQALRPIERESAGKNYNKMHKRERTCKDYIKAVVETVDNLLRPEALESWKDMNATEQVHTATMLLDVLEEGAFLLADNVREPARFLAAKQNVVLEVTVLSTEGQVQELVFPQEYASESSIQLSANTIKQNSRNGVVKVVFILYNNLGLFLSTENATVKLAGEAGTGGPGGASLVVNSQVIAASINKESSRVFLMDPVIFTVAHLEAKNHFNANCSFWNYSERSMLGYWSTQGCRLVESNKTHTTCACSHLTNFAVLMAHREIYQGRINELLLSVITWVGIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINLFLAELLFLVGIDKTQYEVACPIFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVFESEYSRTKYYYLGGYCFPALVVGIAAAIDYRSYGTEKACWLRVDNYFIWSFIGPVSFVIVVNLVFLMVTLHKMIRSSSVLKPDSSRLDNIKSWALGAIALLFLLGLTWAFGLLFINKESVVMAYLFTTFNAFQGVFIFVFHCALQKKVHKEYSKCLRHSYCCIRSPPGGAHGSLKTSAMRSNTRYYTGTQSRIRRMWNDTVRKQTESSFMAGDINSTPTLNRGTMGNHLLTNPVLQPRGGTSPYNTLIAESVGFNPSSPPVFNSPGSYREPKHPLGGREACGMDTLPLNGNFNNSYSLRSGDFPPGDGGPEPPRGRNLADAAAFEKMIISELVHNNLRGASGGAKGPPPEPPVPPVPGVSEDEAGGPGGADRAEIELLYKALEEPLLLPRAQSVLYQSDLDESESCTAEDGATSRPLSSPPGRDSLYASGANLRDSPSYPDSSPEGPNEALPPPPPAPPGPPEIYYTSRPPALVARNPLQGYYQVRRPSHEGYLAAPSLEGPGPDGDGQMQLVTSL

Target ORF information:

RefSeq Version	NM_022962.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus adhesion G protein-coupled receptor L1 (Adgrl1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022962.1

ORF Insert Sequence:

ATGGCCCGCT TGGCTGCAGC ACTCTGGAGT CTCTGTGTGA CGACTGTCCT CGTCACCTCT 
GCTACCCAAG GCCTGAGCCG GGCTGGACTC CCATTTGGAT TGATGCGCCG GGAGCTAGCA 
TGCGAAGGCT ACCCCATTGA GCTGCGGTGC CCGGGCAGTG ACGTCATCAT GGTGGAGAAT 
GCAAACTATG GGCGCACAGA TGACAAGATC TGCGATGCCG ACCCTTTTCA GATGGAGAAC 
GTGCAGTGCT ACCTGCCTGA CGCCTTCAAA ATCATGTCAC AGAGATGTAA TAACCGAACC 
CAGTGTGTGG TGGTGGCCGG CTCTGACGCC TTTCCTGACC CCTGTCCTGG AACCTACAAG 
TACCTGGAGG TGCAGTACGA CTGTGTCCCT TACAAAGTGG AGCAGAAAGT CTTCGTGTGC 
CCAGGGACAC TGCAGAAGGT GCTGGAGCCC ACCTCCACAC ATGAATCGGA GCACCAGTCT 
GGCGCATGGT GCAAGGACCC ACTGCAGGCA GGTGACCGTA TCTACGTTAT GCCCTGGATC 
CCCTACCGCA CGGACACACT GACCGAGTAT GCTTCCTGGG AGGACTATGT GGCTGCACGC 
CACACCACCA CGTACAGACT GCCCAACCGT GTAGATGGCA CTGGCTTTGT GGTATATGAT 
GGTGCCGTCT TCTATAACAA GGAACGTACT CGCAACATTG TCAAATATGA CCTGCGGACC 
CGCATCAAGA GCGGAGAAAC AGTCATAAAC ACAGCCAACT ACCACGACAC CTCACCTTAT 
CGCTGGGGAG GCAAAACCGA CATTGACCTG GCAGTGGATG AGAACGGGCT GTGGGTCATC 
TATGCCACCG AGGGGAACAA CGGGCGTCTG GTGGTGAGCC AGCTCAACCC CTACACACTG 
CGTTTCGAGG GCACCTGGGA AACAGGCTAT GACAAGCGCT CAGCCTCCAA TGCCTTCATG 
GTGTGTGGTG TCCTCTATGT GCTGCGCTCT GTTTATGTGG ATGACGACAG TGAGGCAGCA 
GGCAACCGCG TGGACTATGC CTTTAACACC AATGCAAACC GAGAGGAGCC CGTCAGTCTC 
GCCTTCCCCA ACCCCTACCA GTTTGTATCT TCTGTTGACT ACAATCCCCG GGACAACCAG 
CTGTATGTGT GGAACAACTA TTTCGTGGTG CGCTACAGCC TGGAGTTTGG ACCCCCAGAT 
CCCAGTGCTG GCCCAGCCAC TTCCCCACCT CTCAGTACCA CCACCACAGC TCGGCCTACG 
CCCCTCACCA GCACAGCCTC ACCTGCAGCC ACCACTCCAC TCCGCCGGGC GCCCCTCACC 
ACGCACCCAG TAGGTGCCAT CAACCAGCTG GGACCTGACC TGCCTCCAGC CACAGCCCCA 
GCACCCAGTA CCCGGCGGCC TCCAGCCCCC AATCTGCATG TGTCCCCTGA GCTCTTCTGT 
GAACCCCGAG AGGTCCGGCG GGTCCAGTGG CCAGCTACCC AGCAGGGTAT GCTGGTAGAG 
AGACCTTGCC CCAAGGGAAC TCGAGGAATT GCCTCGTTCC AGTGCCTCCC AGCTCTGGGG 
CTCTGGAATC CTCGGGGCCC TGACCTCAGC AACTGCACTT CCCCCTGGGT CAACCAAGTC 
GCCCAGAAGA TCAAGAGTGG AGAGAATGCA GCCAACATTG CTAGTGAGCT GGCCCGCCAC 
ACGCGGGGCT CCATCTATGC TGGGGACGTG TCCTCATCGG TGAAGCTGAT GGAGCAACTG 
CTAGATATCC TGGATGCCCA GCTCCAGGCC CTACGGCCCA TTGAACGAGA GTCAGCTGGC 
AAGAACTACA ATAAGATGCA CAAGCGAGAG AGAACCTGCA AGGACTATAT CAAGGCTGTG 
GTGGAGACAG TGGACAACCT GCTTCGGCCA GAGGCACTTG AGTCATGGAA AGACATGAAT 
GCCACCGAAC AGGTCCATAC GGCCACCATG CTCCTAGATG TCTTAGAGGA GGGTGCCTTC 
CTGCTGGCCG ACAATGTCAG AGAACCTGCT CGCTTCTTGG CTGCCAAGCA GAATGTGGTC 
CTGGAGGTCA CTGTCCTGAG CACAGAGGGT CAAGTGCAGG AGTTGGTGTT CCCCCAGGAG 
TATGCCAGTG AGAGCTCCAT TCAGCTGTCC GCCAACACCA TCAAGCAGAA CAGCCGCAAT 
GGTGTGGTGA AGGTTGTCTT CATTCTCTAC AACAACCTGG GCCTCTTCTT GTCCACGGAG 
AATGCCACAG TGAAGCTGGC AGGTGAGGCA GGGACCGGTG GCCCTGGAGG TGCCTCCCTG 
GTGGTTAACT CACAGGTCAT CGCAGCATCC ATCAATAAGG AGTCCAGCCG TGTCTTCCTC 
ATGGACCCTG TCATCTTTAC TGTGGCCCAC TTGGAGGCCA AGAACCACTT CAATGCAAAC 
TGCTCCTTCT GGAACTACTC AGAGCGCTCC ATGCTGGGCT ACTGGTCAAC CCAGGGCTGC 
CGACTGGTGG AGTCCAATAA GACCCATACC ACATGTGCCT GCAGCCACCT CACCAACTTC 
GCAGTGCTCA TGGCTCACCG AGAGATCTAC CAAGGCCGTA TTAATGAGCT GTTGCTGTCA 
GTCATCACCT GGGTTGGCAT TGTCATCTCC CTGGTCTGTC TGGCTATCTG CATCTCCACC 
TTCTGCTTCC TGCGGGGCCT GCAGACCGAC CGCAACACCA TCCACAAGAA CCTGTGCATC 
AACCTCTTCC TTGCAGAGCT GCTCTTCCTG GTTGGAATAG ACAAAACTCA GTATGAGGTC 
GCCTGCCCTA TCTTTGCGGG CCTGCTGCAC TACTTCTTCC TGGCCGCCTT CTCCTGGCTG 
TGCCTAGAGG GCGTGCACCT CTACCTCCTG CTGGTCGAGG TGTTCGAGAG CGAATATTCA 
CGCACCAAGT ACTATTACCT GGGCGGCTAC TGCTTCCCAG CCCTGGTGGT AGGCATCGCA 
GCCGCCATTG ACTACCGAAG CTACGGCACT GAGAAGGCCT GCTGGCTGAG GGTGGATAAC 
TATTTCATCT GGAGCTTCAT TGGGCCCGTC TCCTTTGTTA TTGTGGTGAA CCTGGTGTTC 
CTCATGGTGA CCCTGCACAA GATGATCCGA AGCTCATCCG TGCTCAAGCC TGACTCCAGC 
CGCCTTGACA ACATCAAGTC CTGGGCGCTG GGTGCCATTG CACTGCTCTT CCTGCTGGGC 
CTCACCTGGG CTTTCGGCCT CCTCTTCATC AACAAGGAGT CAGTAGTAAT GGCTTACCTC 
TTCACAACCT TCAACGCCTT CCAGGGGGTC TTCATCTTTG TCTTTCACTG CGCCTTACAG 
AAAAAGGTGC ACAAGGAGTA CAGCAAGTGC CTGCGTCACT CCTACTGCTG CATTCGCTCC 
CCACCTGGGG GGGCTCACGG CTCCCTTAAG ACCTCAGCCA TGCGAAGTAA CACCCGCTAC 
TACACAGGGA CCCAGAGCCG AATCCGGAGG ATGTGGAATG ACACCGTGAG GAAGCAGACA 
GAGTCGTCCT TTATGGCAGG GGACATCAAC AGCACCCCCA CCCTGAACCG AGGTACCATG 
GGGAACCACC TACTGACCAA CCCTGTGCTA CAGCCCCGTG GGGGCACTAG CCCATACAAT 
ACACTCATTG CAGAGTCTGT GGGCTTCAAT CCCTCCTCGC CCCCAGTCTT CAACTCCCCA 
GGAAGCTACA GGGAACCTAA GCACCCCTTG GGCGGCCGGG AAGCCTGTGG CATGGACACA 
CTGCCCCTTA ATGGCAACTT CAACAACAGC TACTCCTTGC GAAGTGGTGA TTTCCCTCCG 
GGGGATGGGG GTCCTGAGCC ACCCCGAGGC CGAAACCTAG CGGATGCTGC GGCCTTTGAG 
AAGATGATCA TCTCAGAGCT GGTGCACAAC AACCTTCGGG GGGCCAGTGG GGGCGCCAAA 
GGTCCTCCAC CAGAGCCTCC TGTGCCACCC GTGCCAGGAG TCAGTGAGGA CGAGGCTGGT 
GGGCCTGGGG GTGCTGACCG GGCTGAGATT GAACTTCTCT ACAAGGCCCT GGAGGAGCCA 
CTGCTGCTGC CCCGGGCCCA GTCGGTGCTG TACCAGAGTG ATCTGGATGA GTCGGAGAGC 
TGTACGGCAG AGGATGGGGC CACCAGCCGG CCCCTCTCCT CCCCTCCCGG CCGGGACTCC 
CTCTATGCCA GCGGGGCCAA CCTGCGGGAC TCGCCCTCCT ACCCGGACAG CAGCCCCGAA 
GGGCCTAATG AGGCCCTGCC CCCTCCCCCA CCTGCTCCCC CTGGGCCCCC AGAAATCTAC 
TACACCTCTC GCCCGCCGGC CCTGGTGGCT CGGAATCCCC TACAGGGCTA CTACCAGGTG 
CGGCGGCCCA GCCATGAGGG CTACCTGGCA GCCCCCAGCC TTGAGGGGCC AGGGCCCGAT 
GGGGATGGGC AAATGCAGTT GGTCACTAGT CTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Calsyntenins function as synaptogenic adhesion molecules in concert with neurexins.
Cell reports6(6)1096-1109(2014 Mar)
Um JW,Pramanik G,Ko JS,Song MY,Lee D,Kim H,Park KS,S?dhof TC,Tabuchi K,Ko J

High affinity neurexin binding to cell adhesion G-protein-coupled receptor CIRL1/latrophilin-1 produces an intercellular adhesion complex.
The Journal of biological chemistry287(12)9399-413(2012 Mar)
Boucard AA,Ko J,S?dhof TC

Latrophilin 1 and its endogenous ligand Lasso/teneurin-2 form a high-affinity transsynaptic receptor pair with signaling capabilities.
Proceedings of the National Academy of Sciences of the United States of America108(29)12113-8(2011 Jul)
Silva JP,Lelianova VG,Ermolyuk YS,Vysokov N,Hitchen PG,Berninghausen O,Rahman MA,Zangrandi A,Fidalgo S,Tonevitsky AG,Dell A,Volynski KE,Ushkaryov YA

Dissociation of the subunits of the calcium-independent receptor of alpha-latrotoxin as a result of two-step proteolysis.
Biochemistry48(14)3230-8(2009 Apr)
Krasnoperov V,Deyev IE,Serova OV,Xu C,Lu Y,Buryanovsky L,Gabibov AG,Neubert TA,Petrenko AG

Post-translational proteolytic processing of the calcium-independent receptor of alpha-latrotoxin (CIRL), a natural chimera of the cell adhesion protein and the G protein-coupled receptor. Role of the G protein-coupled receptor proteolysis site (GPS) motif.
The Journal of biological chemistry277(48)46518-26(2002 Nov)
Krasnoperov V,Lu Y,Buryanovsky L,Neubert TA,Ichtchenko K,Petrenko AG

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Adgrl1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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