Tfrc cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tfrc
Entrez Gene ID	64678
Full Name	transferrin receptor
Synonyms	Trfr
General protein information	Preferred Names transferrin receptor Names transferrin receptor protein 1 TR tfR tfR1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 11 Map Location: 11q22
Summary	receptor for transferrin; involved in regulating stellate cell activation [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006248462.3	XP_006248524.1	transferrin receptor protein 1 isoform X1
NM_022712.1	NP_073203.1	transferrin receptor protein 1
XM_006248463.3	XP_006248525.1	transferrin receptor protein 1 isoform X1

Pathways from BioSystems

Homologies

	TFRC	XP_001101412.2
Danio rerio (zebrafish)	tfr1b	NP_001009918.2
Danio rerio (zebrafish)	LOC100333875	XP_002666703.1
Homo sapiens (human)	TFRC	NP_001121620.1
Xenopus tropicalis (tropical clawed frog)	LOC101734813	XP_004920006.1
Pan troglodytes (chimpanzee)	TFRC	XP_003310238.1
Mus musculus (house mouse)	Tfrc	NP_035768.1
Canis lupus familiaris (dog)	TFRC	NP_001003111.1
Bos taurus (cattle)	TFRC	NP_001193506.1
Xenopus tropicalis (tropical clawed frog)	tfrc	XP_002934101.2
Rattus norvegicus (Norway rat)	Tfrc	NP_073203.1
Gallus gallus (chicken)	TFRC	NP_990587.1
Danio rerio (zebrafish)	tfr1a	NP_001009917.1

Gene Ontology
Bibliography

Related articles in PubMed

Transferrin receptor 1 is a reticulocyte-specific receptor for
Gruszczyk J, Kanjee U, Chan LJ, Menant S, Malleret B, Lim NTY, Schmidt CQ, Mok YF, Lin KM, Pearson RD, Rangel G, Smith BJ, Call MJ, Weekes MP, Griffin MDW, Murphy JM, Abraham J, Sriprawat K, Menezes MJ, Ferreira MU, Russell B, Renia L, Duraisingh MT, Tham WH
Science (New York, N.Y.)359(6371)48-55(2018 01)

The Endocytic Fate of the Transferrin Receptor Is Regulated by c-Abl Kinase.
Cao H, Schroeder B, Chen J, Schott MB, McNiven MA
The Journal of biological chemistry291(32)16424-37(2016 08)

Differential Targeting of SLC30A10/ZnT10 Heterodimers to Endolysosomal Compartments Modulates EGF-Induced MEK/ERK1/2 Activity.
Zhao Y, Feresin RG, Falcon-Perez JM, Salazar G
Traffic (Copenhagen, Denmark)17(3)267-88(2016 Mar)

A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency.
Jabara HH, Boyden SE, Chou J, Ramesh N, Massaad MJ, Benson H, Bainter W, Fraulino D, Rahimov F, Sieff C, Liu ZJ, Alshemmari SH, Al-Ramadi BK, Al-Dhekri H, Arnaout R, Abu-Shukair M, Vatsayan A, Silver E, Ahuja S, Davies EG, Sola-Visner M, Ohsumi TK, Andrews NC, Notarangelo LD, Fleming MD, Al-Herz W, Kunkel LM, Geha RS
Nature genetics48(1)74-8(2016 Jan)

Novel Role of TRPML2 in the Regulation of the Innate Immune Response.
Sun L, Hua Y, Vergarajauregui S, Diab HI, Puertollano R
Journal of immunology (Baltimore, Md. : 1950)195(10)4922-32(2015 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

inhibition of c-Abl minimizes receptor recycling pathways and results in chaperone-dependent trafficking of the TfR1 to the lysosome for degradation.
Title: The Endocytic Fate of the Transferrin Receptor Is Regulated by c-Abl Kinase.

the effects of hepcidin expression and hepcidin peptide on brain iron contents, iron transport across the brain-blood barrier, iron uptake and release, and also the expression of TfR1, DMT1, and Fpn, were investigated.
Title: Hepcidin Suppresses Brain Iron Accumulation by Downregulating Iron Transport Proteins in Iron-Overloaded Rats.

Nuclear localization for Zip8 and Zip14 transporters as well as TfR1 was observed in the inner ear of rats.
Title: Cellular localization and developmental changes of Zip8, Zip14 and transferrin receptor 1 in the inner ear of rats.

Whole-genome profiling reveals that increasing dietary protein from 5 to 40% increass duodenal transcript expression of divalent metal transporter 1 (DMT1) 3.2-fold, duodenal cytochrome b (Dcytb) 1.8-fold, and transferrin receptor (TfR) 1.8-fold.
Title: Increasing dietary protein acutely augments intestinal iron transporter expression and significantly increases iron absorption in rats.

Data suggest that soluble transferrin receptor (sTfR) indices and the ratio of sTfR/ferritin could be useful indicators for monitoring iron deficiency during endurance training.
Title: The ratio of sTfR/ferritin is associated with the expression level of TfR in rat bone marrow cells after endurance exercise.

The following Tfrc gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tfrc cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa06317	NM_022712.1 Latest version!	Rattus norvegicus transferrin receptor (Tfrc), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$391.30 $559.00
ORa06317	XM_006248462.3 Latest version!	Rattus norvegicus transferrin receptor (Tfrc), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$391.30 $559.00
ORa06317	XM_006248463.3 Latest version!	Rattus norvegicus transferrin receptor (Tfrc), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$391.30 $559.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tfrc ( NM_022712.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_073203.1 Rattus norvegicus transferrin receptor (Tfrc), mRNA.

Price & Availability↑

CloneID	ORa06317
Clone ID Related Accession (Same CDS sequence)	XM_006248462.3 , NM_022712.1 , XM_006248463.3
Accession Version	NM_022712.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2286bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-03
Organism	Rattus norvegicus(Norway rat)
Product	transferrin receptor protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CB762571.1, CB809947.1, BP500872.1, FM033330.1, CB700894.1, CV117527.1, CV111368.1, CV117299.1, FM123390.1, CO398424.1, AI029320.1 and CA509549.1. On or before Dec 17, 2009 this sequence version replaced XM_340999.3, XM_001072774.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN01906349, SAMN01906350 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATGGATC AAGCCAGATC AGCATTCTCT AACTTGTTTG GAGGGGAGCC ATTGTCATAC 
ACCCGGTTTA GCCTTGCTCG GCAAGTAGAT GGAGATAACA GTCATGTGGA GATGAAACTG 
GCTGCAGATG AGGAAGAAAA TGCTGACAGT AACATGAAGG CTAGTGTCAG AAAACCCAAA 
AGGTTTAATG GAAGACTCTG CTTTGCGACT ATTGCAGTAG TCATCTTTTT TTTGATTGGA 
TTTATGATCG GCTACCTGGG CTATTGTAAG CGCGTAGAAC AAAAAGAGGA GTGTGTGAGA 
CTGGCTGAAG CGGAAGAGGC GGACAAGTCA GAAAACGACG AAACAGAATA TGTTCCTAAA 
TCTTCTCGCT TATTTTGGGC AGACCTCAAA ACACTGTTGT CAGAGAAATT GAATTCCATA 
GAGTTCACTG ACATCATCAA GCAGCTGAGC CAGAATACAT ATACTCCTCG TGAGGCTGGA 
TCTCAGAAAG ACGAGAATCT TGCCTATTAT ATTGAAAATC TGTTCCATGA CTTTAAATTC 
AGCAAAGTCT GGCGAGATGA ACATTATGTG AAGATTCAAG TGAAAAACAG TGTTTCTCAA 
AACTTGGTGA CCATAAATTC AGGTAGTAAC ATTGACCCAG TGGAGGCTCC TGAGGGTTAT 
GTGGCATTTA GTAAAGCTGG AGAAGTTACT GGTAAACTGG TCCATGCTAA TTTTGGCACT 
AAAAAGGACT TTGAAGAATT AAATTATTCT GTGAATGGAT CTTTAGTGAT TGTTAGAGCA 
GGGAAAATTA CTTTTGCAGA AAAGGTTGCA AATGCCCAAA GCTTTAATGC AATTGGTGTC 
CTCATCTACA TGGACAGGAA TACGTTCCCC GTTGTTGAGG CAGACCTTCA ATTCTTTGGA 
CATGCTCATC TAGGAACTGG GGATCCATAT ACACCTGGCT TTCCTTCTTT CAACCATACT 
CAGTTTCCGC CATCTCAGTC ATCTGGATTG CCTTCTATAC CTGTGCAGAC GATCTCAAGA 
GCTGCTGCAG AAAAGCTATT CAAAAACATG GAAGGAAACT GTCCTCCTAG TTGGAATATA 
GATTCCTCAT GTAAGCTGGA ACTTTCACAG AATCAAAATG TGAAGCTCAC TGTGAACAAT 
GTACTGAAAG AAACAAGAAT ACTTAACATC TTTGGCGTTA TTAAAGGCTA TGAGGAACCA 
GACCGCTACA TTGTAGTAGG AGCCCAGAGA GACGCTTGGG GCCCTGGTGT TGCGAAGTCC 
AGTGTGGGAA CAGGTCTTCT GTTGAAACTT GCCCAAGTAT TCTCAGATAT GATTTCAAAA 
GATGGATTTA GACCCAGCAG GAGTATTATC TTTGCCAGCT GGACTGCAGG AGACTATGGA 
GCTGTTGGTG CCACTGAGTG GCTGGAGGGG TACCTTTCAT CTTTGCATCT AAAGGCTTTC 
ACTTACATTA ATCTGGATAA AGTCGTCCTG GGTACTAGCA ACTTCAAGGT TTCTGCCAGC 
CCCCTATTAT ATACACTTAT GGGGAAGATA ATGCAGGACG TAAAGCATCC GATTGATGGA 
AAATATCTAT ATCGAGACAG TAATTGGATT AGCAAAATTG AGGAACTTTC CTTGGACAAT 
GCTGCATTCC CTTTTCTTGC ATATTCAGGA ATCCCAGCAG TTTCTTTCTG TTTTTGTGAG 
GATGAGGACT ATCCTTATTT GGGCACTAAA CTAGATACCT ATGAGATATT AATTCAGAAA 
GTTCCTCAGC TCAACCAAAT GGTTCGTACA GCAGCAGAGG TGGCCGGTCA GTTCATTATT 
AAACTTACCC ATGACATTGA GTTGACCCTG GACTATGAGA TGTACAACAG CAAACTACTG 
TCATTTATGA AGGATCTGAA CCAGTTCAAA GCAGATATCA AAGATATGGG TCTAAGTCTA 
CAATGGCTGT ATTCTGCTCG TGGAGACTAC TTCCGTGCTA CTTCTAGACT AACAACTGAT 
TTTCATAATG CTGAGAAAAC AAACAGATTC GTCATGAGGG AAATCAATGA TCGTATTATG 
AAAGTGGAGT ATCACTTCCT GTCACCCTAT GTATCTCCAA GAGAGTCTCC TTTCCGACAC 
ATCTTCTGGG GCTCTGGCTC TCACACCCTC TCAGCTTTAG TGGAGAACCT GAGACTTCGT 
CAGAAAAATA TCACTGCTTT CAATGAAACG CTCTTCAGAA ACCAGTTGGC CCTGGCTACG 
TGGACTATTC AGGGAGTTGC AAATGCCCTC TCTGGTGACA TTTGGAATAT TGACAATGAG 
TTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_073203.1
CDS	134..2419
Translation	MMDQARSAFSNLFGGEPLSYTRFSLARQVDGDNSHVEMKLAADEEENADSNMKASVRKPKRFNGRLCFATIAVVIFFLIGFMIGYLGYCKRVEQKEECVRLAEAEEADKSENDETEYVPKSSRLFWADLKTLLSEKLNSIEFTDIIKQLSQNTYTPREAGSQKDENLAYYIENLFHDFKFSKVWRDEHYVKIQVKNSVSQNLVTINSGSNIDPVEAPEGYVAFSKAGEVTGKLVHANFGTKKDFEELNYSVNGSLVIVRAGKITFAEKVANAQSFNAIGVLIYMDRNTFPVVEADLQFFGHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPSIPVQTISRAAAEKLFKNMEGNCPPSWNIDSSCKLELSQNQNVKLTVNNVLKETRILNIFGVIKGYEEPDRYIVVGAQRDAWGPGVAKSSVGTGLLLKLAQVFSDMISKDGFRPSRSIIFASWTAGDYGAVGATEWLEGYLSSLHLKAFTYINLDKVVLGTSNFKVSASPLLYTLMGKIMQDVKHPIDGKYLYRDSNWISKIEELSLDNAAFPFLAYSGIPAVSFCFCEDEDYPYLGTKLDTYEILIQKVPQLNQMVRTAAEVAGQFIIKLTHDIELTLDYEMYNSKLLSFMKDLNQFKADIKDMGLSLQWLYSARGDYFRATSRLTTDFHNAEKTNRFVMREINDRIMKVEYHFLSPYVSPRESPFRHIFWGSGSHTLSALVENLRLRQKNITAFNETLFRNQLALATWTIQGVANALSGDIWNIDNEF

Target ORF information:

RefSeq Version	NM_022712.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus transferrin receptor (Tfrc), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022712.1

ORF Insert Sequence:

ATGATGGATC AAGCCAGATC AGCATTCTCT AACTTGTTTG GAGGGGAGCC ATTGTCATAC 
ACCCGGTTTA GCCTTGCTCG GCAAGTAGAT GGAGATAACA GTCATGTGGA GATGAAACTG 
GCTGCAGATG AGGAAGAAAA TGCTGACAGT AACATGAAGG CTAGTGTCAG AAAACCCAAA 
AGGTTTAATG GAAGACTCTG CTTTGCGACT ATTGCAGTAG TCATCTTTTT TTTGATTGGA 
TTTATGATCG GCTACCTGGG CTATTGTAAG CGCGTAGAAC AAAAAGAGGA GTGTGTGAGA 
CTGGCTGAAG CGGAAGAGGC GGACAAGTCA GAAAACGACG AAACAGAATA TGTTCCTAAA 
TCTTCTCGCT TATTTTGGGC AGACCTCAAA ACACTGTTGT CAGAGAAATT GAATTCCATA 
GAGTTCACTG ACATCATCAA GCAGCTGAGC CAGAATACAT ATACTCCTCG TGAGGCTGGA 
TCTCAGAAAG ACGAGAATCT TGCCTATTAT ATTGAAAATC TGTTCCATGA CTTTAAATTC 
AGCAAAGTCT GGCGAGATGA ACATTATGTG AAGATTCAAG TGAAAAACAG TGTTTCTCAA 
AACTTGGTGA CCATAAATTC AGGTAGTAAC ATTGACCCAG TGGAGGCTCC TGAGGGTTAT 
GTGGCATTTA GTAAAGCTGG AGAAGTTACT GGTAAACTGG TCCATGCTAA TTTTGGCACT 
AAAAAGGACT TTGAAGAATT AAATTATTCT GTGAATGGAT CTTTAGTGAT TGTTAGAGCA 
GGGAAAATTA CTTTTGCAGA AAAGGTTGCA AATGCCCAAA GCTTTAATGC AATTGGTGTC 
CTCATCTACA TGGACAGGAA TACGTTCCCC GTTGTTGAGG CAGACCTTCA ATTCTTTGGA 
CATGCTCATC TAGGAACTGG GGATCCATAT ACACCTGGCT TTCCTTCTTT CAACCATACT 
CAGTTTCCGC CATCTCAGTC ATCTGGATTG CCTTCTATAC CTGTGCAGAC GATCTCAAGA 
GCTGCTGCAG AAAAGCTATT CAAAAACATG GAAGGAAACT GTCCTCCTAG TTGGAATATA 
GATTCCTCAT GTAAGCTGGA ACTTTCACAG AATCAAAATG TGAAGCTCAC TGTGAACAAT 
GTACTGAAAG AAACAAGAAT ACTTAACATC TTTGGCGTTA TTAAAGGCTA TGAGGAACCA 
GACCGCTACA TTGTAGTAGG AGCCCAGAGA GACGCTTGGG GCCCTGGTGT TGCGAAGTCC 
AGTGTGGGAA CAGGTCTTCT GTTGAAACTT GCCCAAGTAT TCTCAGATAT GATTTCAAAA 
GATGGATTTA GACCCAGCAG GAGTATTATC TTTGCCAGCT GGACTGCAGG AGACTATGGA 
GCTGTTGGTG CCACTGAGTG GCTGGAGGGG TACCTTTCAT CTTTGCATCT AAAGGCTTTC 
ACTTACATTA ATCTGGATAA AGTCGTCCTG GGTACTAGCA ACTTCAAGGT TTCTGCCAGC 
CCCCTATTAT ATACACTTAT GGGGAAGATA ATGCAGGACG TAAAGCATCC GATTGATGGA 
AAATATCTAT ATCGAGACAG TAATTGGATT AGCAAAATTG AGGAACTTTC CTTGGACAAT 
GCTGCATTCC CTTTTCTTGC ATATTCAGGA ATCCCAGCAG TTTCTTTCTG TTTTTGTGAG 
GATGAGGACT ATCCTTATTT GGGCACTAAA CTAGATACCT ATGAGATATT AATTCAGAAA 
GTTCCTCAGC TCAACCAAAT GGTTCGTACA GCAGCAGAGG TGGCCGGTCA GTTCATTATT 
AAACTTACCC ATGACATTGA GTTGACCCTG GACTATGAGA TGTACAACAG CAAACTACTG 
TCATTTATGA AGGATCTGAA CCAGTTCAAA GCAGATATCA AAGATATGGG TCTAAGTCTA 
CAATGGCTGT ATTCTGCTCG TGGAGACTAC TTCCGTGCTA CTTCTAGACT AACAACTGAT 
TTTCATAATG CTGAGAAAAC AAACAGATTC GTCATGAGGG AAATCAATGA TCGTATTATG 
AAAGTGGAGT ATCACTTCCT GTCACCCTAT GTATCTCCAA GAGAGTCTCC TTTCCGACAC 
ATCTTCTGGG GCTCTGGCTC TCACACCCTC TCAGCTTTAG TGGAGAACCT GAGACTTCGT 
CAGAAAAATA TCACTGCTTT CAATGAAACG CTCTTCAGAA ACCAGTTGGC CCTGGCTACG 
TGGACTATTC AGGGAGTTGC AAATGCCCTC TCTGGTGACA TTTGGAATAT TGACAATGAG 
TTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tfrc ( XM_006248462.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006248524.1 Rattus norvegicus transferrin receptor (Tfrc), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa06317
Clone ID Related Accession (Same CDS sequence)	XM_006248462.3 , NM_022712.1 , XM_006248463.3
Accession Version	XM_006248462.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2286bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	transferrin receptor protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005110.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006248462.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATGGATC AAGCCAGATC AGCATTCTCT AACTTGTTTG GAGGGGAGCC ATTGTCATAC 
ACCCGGTTTA GCCTTGCTCG GCAAGTAGAT GGAGATAACA GTCATGTGGA GATGAAACTG 
GCTGCAGATG AGGAAGAAAA TGCTGACAGT AACATGAAGG CTAGTGTCAG AAAACCCAAA 
AGGTTTAATG GAAGACTCTG CTTTGCGACT ATTGCAGTAG TCATCTTTTT TTTGATTGGA 
TTTATGATCG GCTACCTGGG CTATTGTAAG CGCGTAGAAC AAAAAGAGGA GTGTGTGAGA 
CTGGCTGAAG CGGAAGAGGC GGACAAGTCA GAAAACGACG AAACAGAATA TGTTCCTAAA 
TCTTCTCGCT TATTTTGGGC AGACCTCAAA ACACTGTTGT CAGAGAAATT GAATTCCATA 
GAGTTCACTG ACATCATCAA GCAGCTGAGC CAGAATACAT ATACTCCTCG TGAGGCTGGA 
TCTCAGAAAG ACGAGAATCT TGCCTATTAT ATTGAAAATC TGTTCCATGA CTTTAAATTC 
AGCAAAGTCT GGCGAGATGA ACATTATGTG AAGATTCAAG TGAAAAACAG TGTTTCTCAA 
AACTTGGTGA CCATAAATTC AGGTAGTAAC ATTGACCCAG TGGAGGCTCC TGAGGGTTAT 
GTGGCATTTA GTAAAGCTGG AGAAGTTACT GGTAAACTGG TCCATGCTAA TTTTGGCACT 
AAAAAGGACT TTGAAGAATT AAATTATTCT GTGAATGGAT CTTTAGTGAT TGTTAGAGCA 
GGGAAAATTA CTTTTGCAGA AAAGGTTGCA AATGCCCAAA GCTTTAATGC AATTGGTGTC 
CTCATCTACA TGGACAGGAA TACGTTCCCC GTTGTTGAGG CAGACCTTCA ATTCTTTGGA 
CATGCTCATC TAGGAACTGG GGATCCATAT ACACCTGGCT TTCCTTCTTT CAACCATACT 
CAGTTTCCGC CATCTCAGTC ATCTGGATTG CCTTCTATAC CTGTGCAGAC GATCTCAAGA 
GCTGCTGCAG AAAAGCTATT CAAAAACATG GAAGGAAACT GTCCTCCTAG TTGGAATATA 
GATTCCTCAT GTAAGCTGGA ACTTTCACAG AATCAAAATG TGAAGCTCAC TGTGAACAAT 
GTACTGAAAG AAACAAGAAT ACTTAACATC TTTGGCGTTA TTAAAGGCTA TGAGGAACCA 
GACCGCTACA TTGTAGTAGG AGCCCAGAGA GACGCTTGGG GCCCTGGTGT TGCGAAGTCC 
AGTGTGGGAA CAGGTCTTCT GTTGAAACTT GCCCAAGTAT TCTCAGATAT GATTTCAAAA 
GATGGATTTA GACCCAGCAG GAGTATTATC TTTGCCAGCT GGACTGCAGG AGACTATGGA 
GCTGTTGGTG CCACTGAGTG GCTGGAGGGG TACCTTTCAT CTTTGCATCT AAAGGCTTTC 
ACTTACATTA ATCTGGATAA AGTCGTCCTG GGTACTAGCA ACTTCAAGGT TTCTGCCAGC 
CCCCTATTAT ATACACTTAT GGGGAAGATA ATGCAGGACG TAAAGCATCC GATTGATGGA 
AAATATCTAT ATCGAGACAG TAATTGGATT AGCAAAATTG AGGAACTTTC CTTGGACAAT 
GCTGCATTCC CTTTTCTTGC ATATTCAGGA ATCCCAGCAG TTTCTTTCTG TTTTTGTGAG 
GATGAGGACT ATCCTTATTT GGGCACTAAA CTAGATACCT ATGAGATATT AATTCAGAAA 
GTTCCTCAGC TCAACCAAAT GGTTCGTACA GCAGCAGAGG TGGCCGGTCA GTTCATTATT 
AAACTTACCC ATGACATTGA GTTGACCCTG GACTATGAGA TGTACAACAG CAAACTACTG 
TCATTTATGA AGGATCTGAA CCAGTTCAAA GCAGATATCA AAGATATGGG TCTAAGTCTA 
CAATGGCTGT ATTCTGCTCG TGGAGACTAC TTCCGTGCTA CTTCTAGACT AACAACTGAT 
TTTCATAATG CTGAGAAAAC AAACAGATTC GTCATGAGGG AAATCAATGA TCGTATTATG 
AAAGTGGAGT ATCACTTCCT GTCACCCTAT GTATCTCCAA GAGAGTCTCC TTTCCGACAC 
ATCTTCTGGG GCTCTGGCTC TCACACCCTC TCAGCTTTAG TGGAGAACCT GAGACTTCGT 
CAGAAAAATA TCACTGCTTT CAATGAAACG CTCTTCAGAA ACCAGTTGGC CCTGGCTACG 
TGGACTATTC AGGGAGTTGC AAATGCCCTC TCTGGTGACA TTTGGAATAT TGACAATGAG 
TTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006248524.1
CDS	248..2533
Translation	MMDQARSAFSNLFGGEPLSYTRFSLARQVDGDNSHVEMKLAADEEENADSNMKASVRKPKRFNGRLCFATIAVVIFFLIGFMIGYLGYCKRVEQKEECVRLAEAEEADKSENDETEYVPKSSRLFWADLKTLLSEKLNSIEFTDIIKQLSQNTYTPREAGSQKDENLAYYIENLFHDFKFSKVWRDEHYVKIQVKNSVSQNLVTINSGSNIDPVEAPEGYVAFSKAGEVTGKLVHANFGTKKDFEELNYSVNGSLVIVRAGKITFAEKVANAQSFNAIGVLIYMDRNTFPVVEADLQFFGHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPSIPVQTISRAAAEKLFKNMEGNCPPSWNIDSSCKLELSQNQNVKLTVNNVLKETRILNIFGVIKGYEEPDRYIVVGAQRDAWGPGVAKSSVGTGLLLKLAQVFSDMISKDGFRPSRSIIFASWTAGDYGAVGATEWLEGYLSSLHLKAFTYINLDKVVLGTSNFKVSASPLLYTLMGKIMQDVKHPIDGKYLYRDSNWISKIEELSLDNAAFPFLAYSGIPAVSFCFCEDEDYPYLGTKLDTYEILIQKVPQLNQMVRTAAEVAGQFIIKLTHDIELTLDYEMYNSKLLSFMKDLNQFKADIKDMGLSLQWLYSARGDYFRATSRLTTDFHNAEKTNRFVMREINDRIMKVEYHFLSPYVSPRESPFRHIFWGSGSHTLSALVENLRLRQKNITAFNETLFRNQLALATWTIQGVANALSGDIWNIDNEF

Target ORF information:

RefSeq Version	XM_006248462.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus transferrin receptor (Tfrc), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006248462.3

ORF Insert Sequence:

ATGATGGATC AAGCCAGATC AGCATTCTCT AACTTGTTTG GAGGGGAGCC ATTGTCATAC 
ACCCGGTTTA GCCTTGCTCG GCAAGTAGAT GGAGATAACA GTCATGTGGA GATGAAACTG 
GCTGCAGATG AGGAAGAAAA TGCTGACAGT AACATGAAGG CTAGTGTCAG AAAACCCAAA 
AGGTTTAATG GAAGACTCTG CTTTGCGACT ATTGCAGTAG TCATCTTTTT TTTGATTGGA 
TTTATGATCG GCTACCTGGG CTATTGTAAG CGCGTAGAAC AAAAAGAGGA GTGTGTGAGA 
CTGGCTGAAG CGGAAGAGGC GGACAAGTCA GAAAACGACG AAACAGAATA TGTTCCTAAA 
TCTTCTCGCT TATTTTGGGC AGACCTCAAA ACACTGTTGT CAGAGAAATT GAATTCCATA 
GAGTTCACTG ACATCATCAA GCAGCTGAGC CAGAATACAT ATACTCCTCG TGAGGCTGGA 
TCTCAGAAAG ACGAGAATCT TGCCTATTAT ATTGAAAATC TGTTCCATGA CTTTAAATTC 
AGCAAAGTCT GGCGAGATGA ACATTATGTG AAGATTCAAG TGAAAAACAG TGTTTCTCAA 
AACTTGGTGA CCATAAATTC AGGTAGTAAC ATTGACCCAG TGGAGGCTCC TGAGGGTTAT 
GTGGCATTTA GTAAAGCTGG AGAAGTTACT GGTAAACTGG TCCATGCTAA TTTTGGCACT 
AAAAAGGACT TTGAAGAATT AAATTATTCT GTGAATGGAT CTTTAGTGAT TGTTAGAGCA 
GGGAAAATTA CTTTTGCAGA AAAGGTTGCA AATGCCCAAA GCTTTAATGC AATTGGTGTC 
CTCATCTACA TGGACAGGAA TACGTTCCCC GTTGTTGAGG CAGACCTTCA ATTCTTTGGA 
CATGCTCATC TAGGAACTGG GGATCCATAT ACACCTGGCT TTCCTTCTTT CAACCATACT 
CAGTTTCCGC CATCTCAGTC ATCTGGATTG CCTTCTATAC CTGTGCAGAC GATCTCAAGA 
GCTGCTGCAG AAAAGCTATT CAAAAACATG GAAGGAAACT GTCCTCCTAG TTGGAATATA 
GATTCCTCAT GTAAGCTGGA ACTTTCACAG AATCAAAATG TGAAGCTCAC TGTGAACAAT 
GTACTGAAAG AAACAAGAAT ACTTAACATC TTTGGCGTTA TTAAAGGCTA TGAGGAACCA 
GACCGCTACA TTGTAGTAGG AGCCCAGAGA GACGCTTGGG GCCCTGGTGT TGCGAAGTCC 
AGTGTGGGAA CAGGTCTTCT GTTGAAACTT GCCCAAGTAT TCTCAGATAT GATTTCAAAA 
GATGGATTTA GACCCAGCAG GAGTATTATC TTTGCCAGCT GGACTGCAGG AGACTATGGA 
GCTGTTGGTG CCACTGAGTG GCTGGAGGGG TACCTTTCAT CTTTGCATCT AAAGGCTTTC 
ACTTACATTA ATCTGGATAA AGTCGTCCTG GGTACTAGCA ACTTCAAGGT TTCTGCCAGC 
CCCCTATTAT ATACACTTAT GGGGAAGATA ATGCAGGACG TAAAGCATCC GATTGATGGA 
AAATATCTAT ATCGAGACAG TAATTGGATT AGCAAAATTG AGGAACTTTC CTTGGACAAT 
GCTGCATTCC CTTTTCTTGC ATATTCAGGA ATCCCAGCAG TTTCTTTCTG TTTTTGTGAG 
GATGAGGACT ATCCTTATTT GGGCACTAAA CTAGATACCT ATGAGATATT AATTCAGAAA 
GTTCCTCAGC TCAACCAAAT GGTTCGTACA GCAGCAGAGG TGGCCGGTCA GTTCATTATT 
AAACTTACCC ATGACATTGA GTTGACCCTG GACTATGAGA TGTACAACAG CAAACTACTG 
TCATTTATGA AGGATCTGAA CCAGTTCAAA GCAGATATCA AAGATATGGG TCTAAGTCTA 
CAATGGCTGT ATTCTGCTCG TGGAGACTAC TTCCGTGCTA CTTCTAGACT AACAACTGAT 
TTTCATAATG CTGAGAAAAC AAACAGATTC GTCATGAGGG AAATCAATGA TCGTATTATG 
AAAGTGGAGT ATCACTTCCT GTCACCCTAT GTATCTCCAA GAGAGTCTCC TTTCCGACAC 
ATCTTCTGGG GCTCTGGCTC TCACACCCTC TCAGCTTTAG TGGAGAACCT GAGACTTCGT 
CAGAAAAATA TCACTGCTTT CAATGAAACG CTCTTCAGAA ACCAGTTGGC CCTGGCTACG 
TGGACTATTC AGGGAGTTGC AAATGCCCTC TCTGGTGACA TTTGGAATAT TGACAATGAG 
TTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tfrc ( XM_006248463.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006248525.1 Rattus norvegicus transferrin receptor (Tfrc), transcript variant X1, mRNA.

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CloneID	ORa06317
Clone ID Related Accession (Same CDS sequence)	XM_006248462.3 , NM_022712.1 , XM_006248463.3
Accession Version	XM_006248463.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2286bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	transferrin receptor protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005110.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006248463.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATGGATC AAGCCAGATC AGCATTCTCT AACTTGTTTG GAGGGGAGCC ATTGTCATAC 
ACCCGGTTTA GCCTTGCTCG GCAAGTAGAT GGAGATAACA GTCATGTGGA GATGAAACTG 
GCTGCAGATG AGGAAGAAAA TGCTGACAGT AACATGAAGG CTAGTGTCAG AAAACCCAAA 
AGGTTTAATG GAAGACTCTG CTTTGCGACT ATTGCAGTAG TCATCTTTTT TTTGATTGGA 
TTTATGATCG GCTACCTGGG CTATTGTAAG CGCGTAGAAC AAAAAGAGGA GTGTGTGAGA 
CTGGCTGAAG CGGAAGAGGC GGACAAGTCA GAAAACGACG AAACAGAATA TGTTCCTAAA 
TCTTCTCGCT TATTTTGGGC AGACCTCAAA ACACTGTTGT CAGAGAAATT GAATTCCATA 
GAGTTCACTG ACATCATCAA GCAGCTGAGC CAGAATACAT ATACTCCTCG TGAGGCTGGA 
TCTCAGAAAG ACGAGAATCT TGCCTATTAT ATTGAAAATC TGTTCCATGA CTTTAAATTC 
AGCAAAGTCT GGCGAGATGA ACATTATGTG AAGATTCAAG TGAAAAACAG TGTTTCTCAA 
AACTTGGTGA CCATAAATTC AGGTAGTAAC ATTGACCCAG TGGAGGCTCC TGAGGGTTAT 
GTGGCATTTA GTAAAGCTGG AGAAGTTACT GGTAAACTGG TCCATGCTAA TTTTGGCACT 
AAAAAGGACT TTGAAGAATT AAATTATTCT GTGAATGGAT CTTTAGTGAT TGTTAGAGCA 
GGGAAAATTA CTTTTGCAGA AAAGGTTGCA AATGCCCAAA GCTTTAATGC AATTGGTGTC 
CTCATCTACA TGGACAGGAA TACGTTCCCC GTTGTTGAGG CAGACCTTCA ATTCTTTGGA 
CATGCTCATC TAGGAACTGG GGATCCATAT ACACCTGGCT TTCCTTCTTT CAACCATACT 
CAGTTTCCGC CATCTCAGTC ATCTGGATTG CCTTCTATAC CTGTGCAGAC GATCTCAAGA 
GCTGCTGCAG AAAAGCTATT CAAAAACATG GAAGGAAACT GTCCTCCTAG TTGGAATATA 
GATTCCTCAT GTAAGCTGGA ACTTTCACAG AATCAAAATG TGAAGCTCAC TGTGAACAAT 
GTACTGAAAG AAACAAGAAT ACTTAACATC TTTGGCGTTA TTAAAGGCTA TGAGGAACCA 
GACCGCTACA TTGTAGTAGG AGCCCAGAGA GACGCTTGGG GCCCTGGTGT TGCGAAGTCC 
AGTGTGGGAA CAGGTCTTCT GTTGAAACTT GCCCAAGTAT TCTCAGATAT GATTTCAAAA 
GATGGATTTA GACCCAGCAG GAGTATTATC TTTGCCAGCT GGACTGCAGG AGACTATGGA 
GCTGTTGGTG CCACTGAGTG GCTGGAGGGG TACCTTTCAT CTTTGCATCT AAAGGCTTTC 
ACTTACATTA ATCTGGATAA AGTCGTCCTG GGTACTAGCA ACTTCAAGGT TTCTGCCAGC 
CCCCTATTAT ATACACTTAT GGGGAAGATA ATGCAGGACG TAAAGCATCC GATTGATGGA 
AAATATCTAT ATCGAGACAG TAATTGGATT AGCAAAATTG AGGAACTTTC CTTGGACAAT 
GCTGCATTCC CTTTTCTTGC ATATTCAGGA ATCCCAGCAG TTTCTTTCTG TTTTTGTGAG 
GATGAGGACT ATCCTTATTT GGGCACTAAA CTAGATACCT ATGAGATATT AATTCAGAAA 
GTTCCTCAGC TCAACCAAAT GGTTCGTACA GCAGCAGAGG TGGCCGGTCA GTTCATTATT 
AAACTTACCC ATGACATTGA GTTGACCCTG GACTATGAGA TGTACAACAG CAAACTACTG 
TCATTTATGA AGGATCTGAA CCAGTTCAAA GCAGATATCA AAGATATGGG TCTAAGTCTA 
CAATGGCTGT ATTCTGCTCG TGGAGACTAC TTCCGTGCTA CTTCTAGACT AACAACTGAT 
TTTCATAATG CTGAGAAAAC AAACAGATTC GTCATGAGGG AAATCAATGA TCGTATTATG 
AAAGTGGAGT ATCACTTCCT GTCACCCTAT GTATCTCCAA GAGAGTCTCC TTTCCGACAC 
ATCTTCTGGG GCTCTGGCTC TCACACCCTC TCAGCTTTAG TGGAGAACCT GAGACTTCGT 
CAGAAAAATA TCACTGCTTT CAATGAAACG CTCTTCAGAA ACCAGTTGGC CCTGGCTACG 
TGGACTATTC AGGGAGTTGC AAATGCCCTC TCTGGTGACA TTTGGAATAT TGACAATGAG 
TTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006248525.1
CDS	160..2445
Translation	MMDQARSAFSNLFGGEPLSYTRFSLARQVDGDNSHVEMKLAADEEENADSNMKASVRKPKRFNGRLCFATIAVVIFFLIGFMIGYLGYCKRVEQKEECVRLAEAEEADKSENDETEYVPKSSRLFWADLKTLLSEKLNSIEFTDIIKQLSQNTYTPREAGSQKDENLAYYIENLFHDFKFSKVWRDEHYVKIQVKNSVSQNLVTINSGSNIDPVEAPEGYVAFSKAGEVTGKLVHANFGTKKDFEELNYSVNGSLVIVRAGKITFAEKVANAQSFNAIGVLIYMDRNTFPVVEADLQFFGHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPSIPVQTISRAAAEKLFKNMEGNCPPSWNIDSSCKLELSQNQNVKLTVNNVLKETRILNIFGVIKGYEEPDRYIVVGAQRDAWGPGVAKSSVGTGLLLKLAQVFSDMISKDGFRPSRSIIFASWTAGDYGAVGATEWLEGYLSSLHLKAFTYINLDKVVLGTSNFKVSASPLLYTLMGKIMQDVKHPIDGKYLYRDSNWISKIEELSLDNAAFPFLAYSGIPAVSFCFCEDEDYPYLGTKLDTYEILIQKVPQLNQMVRTAAEVAGQFIIKLTHDIELTLDYEMYNSKLLSFMKDLNQFKADIKDMGLSLQWLYSARGDYFRATSRLTTDFHNAEKTNRFVMREINDRIMKVEYHFLSPYVSPRESPFRHIFWGSGSHTLSALVENLRLRQKNITAFNETLFRNQLALATWTIQGVANALSGDIWNIDNEF

Target ORF information:

RefSeq Version	XM_006248463.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus transferrin receptor (Tfrc), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006248463.3

ORF Insert Sequence:

ATGATGGATC AAGCCAGATC AGCATTCTCT AACTTGTTTG GAGGGGAGCC ATTGTCATAC 
ACCCGGTTTA GCCTTGCTCG GCAAGTAGAT GGAGATAACA GTCATGTGGA GATGAAACTG 
GCTGCAGATG AGGAAGAAAA TGCTGACAGT AACATGAAGG CTAGTGTCAG AAAACCCAAA 
AGGTTTAATG GAAGACTCTG CTTTGCGACT ATTGCAGTAG TCATCTTTTT TTTGATTGGA 
TTTATGATCG GCTACCTGGG CTATTGTAAG CGCGTAGAAC AAAAAGAGGA GTGTGTGAGA 
CTGGCTGAAG CGGAAGAGGC GGACAAGTCA GAAAACGACG AAACAGAATA TGTTCCTAAA 
TCTTCTCGCT TATTTTGGGC AGACCTCAAA ACACTGTTGT CAGAGAAATT GAATTCCATA 
GAGTTCACTG ACATCATCAA GCAGCTGAGC CAGAATACAT ATACTCCTCG TGAGGCTGGA 
TCTCAGAAAG ACGAGAATCT TGCCTATTAT ATTGAAAATC TGTTCCATGA CTTTAAATTC 
AGCAAAGTCT GGCGAGATGA ACATTATGTG AAGATTCAAG TGAAAAACAG TGTTTCTCAA 
AACTTGGTGA CCATAAATTC AGGTAGTAAC ATTGACCCAG TGGAGGCTCC TGAGGGTTAT 
GTGGCATTTA GTAAAGCTGG AGAAGTTACT GGTAAACTGG TCCATGCTAA TTTTGGCACT 
AAAAAGGACT TTGAAGAATT AAATTATTCT GTGAATGGAT CTTTAGTGAT TGTTAGAGCA 
GGGAAAATTA CTTTTGCAGA AAAGGTTGCA AATGCCCAAA GCTTTAATGC AATTGGTGTC 
CTCATCTACA TGGACAGGAA TACGTTCCCC GTTGTTGAGG CAGACCTTCA ATTCTTTGGA 
CATGCTCATC TAGGAACTGG GGATCCATAT ACACCTGGCT TTCCTTCTTT CAACCATACT 
CAGTTTCCGC CATCTCAGTC ATCTGGATTG CCTTCTATAC CTGTGCAGAC GATCTCAAGA 
GCTGCTGCAG AAAAGCTATT CAAAAACATG GAAGGAAACT GTCCTCCTAG TTGGAATATA 
GATTCCTCAT GTAAGCTGGA ACTTTCACAG AATCAAAATG TGAAGCTCAC TGTGAACAAT 
GTACTGAAAG AAACAAGAAT ACTTAACATC TTTGGCGTTA TTAAAGGCTA TGAGGAACCA 
GACCGCTACA TTGTAGTAGG AGCCCAGAGA GACGCTTGGG GCCCTGGTGT TGCGAAGTCC 
AGTGTGGGAA CAGGTCTTCT GTTGAAACTT GCCCAAGTAT TCTCAGATAT GATTTCAAAA 
GATGGATTTA GACCCAGCAG GAGTATTATC TTTGCCAGCT GGACTGCAGG AGACTATGGA 
GCTGTTGGTG CCACTGAGTG GCTGGAGGGG TACCTTTCAT CTTTGCATCT AAAGGCTTTC 
ACTTACATTA ATCTGGATAA AGTCGTCCTG GGTACTAGCA ACTTCAAGGT TTCTGCCAGC 
CCCCTATTAT ATACACTTAT GGGGAAGATA ATGCAGGACG TAAAGCATCC GATTGATGGA 
AAATATCTAT ATCGAGACAG TAATTGGATT AGCAAAATTG AGGAACTTTC CTTGGACAAT 
GCTGCATTCC CTTTTCTTGC ATATTCAGGA ATCCCAGCAG TTTCTTTCTG TTTTTGTGAG 
GATGAGGACT ATCCTTATTT GGGCACTAAA CTAGATACCT ATGAGATATT AATTCAGAAA 
GTTCCTCAGC TCAACCAAAT GGTTCGTACA GCAGCAGAGG TGGCCGGTCA GTTCATTATT 
AAACTTACCC ATGACATTGA GTTGACCCTG GACTATGAGA TGTACAACAG CAAACTACTG 
TCATTTATGA AGGATCTGAA CCAGTTCAAA GCAGATATCA AAGATATGGG TCTAAGTCTA 
CAATGGCTGT ATTCTGCTCG TGGAGACTAC TTCCGTGCTA CTTCTAGACT AACAACTGAT 
TTTCATAATG CTGAGAAAAC AAACAGATTC GTCATGAGGG AAATCAATGA TCGTATTATG 
AAAGTGGAGT ATCACTTCCT GTCACCCTAT GTATCTCCAA GAGAGTCTCC TTTCCGACAC 
ATCTTCTGGG GCTCTGGCTC TCACACCCTC TCAGCTTTAG TGGAGAACCT GAGACTTCGT 
CAGAAAAATA TCACTGCTTT CAATGAAACG CTCTTCAGAA ACCAGTTGGC CCTGGCTACG 
TGGACTATTC AGGGAGTTGC AAATGCCCTC TCTGGTGACA TTTGGAATAT TGACAATGAG 
TTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Transferrin receptor 1 is a reticulocyte-specific receptor for
Science (New York, N.Y.)359(6371)48-55(2018 01)
Gruszczyk J,Kanjee U,Chan LJ,Menant S,Malleret B,Lim NTY,Schmidt CQ,Mok YF,Lin KM,Pearson RD,Rangel G,Smith BJ,Call MJ,Weekes MP,Griffin MDW,Murphy JM,Abraham J,Sriprawat K,Menezes MJ,Ferreira MU,Russell B,Renia L,Duraisingh MT,Tham WH

The Endocytic Fate of the Transferrin Receptor Is Regulated by c-Abl Kinase.
The Journal of biological chemistry291(32)16424-37(2016 08)
Cao H,Schroeder B,Chen J,Schott MB,McNiven MA

Differential Targeting of SLC30A10/ZnT10 Heterodimers to Endolysosomal Compartments Modulates EGF-Induced MEK/ERK1/2 Activity.
Traffic (Copenhagen, Denmark)17(3)267-88(2016 Mar)
Zhao Y,Feresin RG,Falcon-Perez JM,Salazar G

A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency.
Nature genetics48(1)74-8(2016 Jan)
Jabara HH,Boyden SE,Chou J,Ramesh N,Massaad MJ,Benson H,Bainter W,Fraulino D,Rahimov F,Sieff C,Liu ZJ,Alshemmari SH,Al-Ramadi BK,Al-Dhekri H,Arnaout R,Abu-Shukair M,Vatsayan A,Silver E,Ahuja S,Davies EG,Sola-Visner M,Ohsumi TK,Andrews NC,Notarangelo LD,Fleming MD,Al-Herz W,Kunkel LM,Geha RS

Novel Role of TRPML2 in the Regulation of the Innate Immune Response.
Journal of immunology (Baltimore, Md. : 1950)195(10)4922-32(2015 Nov)
Sun L,Hua Y,Vergarajauregui S,Diab HI,Puertollano R

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Tfrc cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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