Bad cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Bad
Entrez Gene ID	64639
Full Name	BCL2-associated agonist of cell death
General protein information	Preferred Names BCL2-associated agonist of cell death Names bcl2-associated agonist of cell death Bcl2-antagonist of cell death bcl-2 associated death agonist bcl-2-binding component 6 bcl-xL/Bcl-2-associated death promoter bcl2 antagonist of cell death bcl2-associated death promoter
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q43
Summary	may be involved in induction of programmed cell death [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006230897.3	XP_006230959.1	bcl2-associated agonist of cell death isoform X2
XM_006230896.3	XP_006230958.1	bcl2-associated agonist of cell death isoform X1
XM_006230898.3	XP_006230960.1	bcl2-associated agonist of cell death isoform X3
NM_022698.1	NP_073189.1	bcl2-associated agonist of cell death

Pathways from BioSystems

Homologies

Homo sapiens (human)	BAD	NP_116784.1
Rattus norvegicus (Norway rat)	Bad	NP_073189.1
Pan troglodytes (chimpanzee)	BAD	NP_001238857.1
	BAD	XP_001115074.1
Bos taurus (cattle)	BAD	NP_001030536.1
Canis lupus familiaris (dog)	BAD	NP_001026990.1
Mus musculus (house mouse)	Bad	NP_031548.1

Gene Ontology
Bibliography

Related articles in PubMed

Chrysin exerts neuroprotective effects against 3-Nitropropionic acid induced behavioral despair-Mitochondrial dysfunction and striatal apoptosis via upregulating Bcl-2 gene and downregulating Bax-Bad genes in male wistar rats.
Thangarajan S, Ramachandran S, Krishnamurthy P
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie84514-525(2016 Dec)

Anti-apoptotic effect of San Huang Shel Shin Tang cyclodextrin complex (SHSSTc) on CCl4 -induced hepatotoxicity in rats.
Yang CH, Ting WJ, Shen CY, Hsu HH, Lin YM, Kuo CH, Tsai FJ, Tsai CH, Tsai Y, Huang CY
Environmental toxicology31(6)663-70(2016 Jun)

Astaxanthin alleviates early brain injury following subarachnoid hemorrhage in rats: possible involvement of Akt/bad signaling.
Zhang XS, Zhang X, Wu Q, Li W, Zhang QR, Wang CX, Zhou XM, Li H, Shi JX, Zhou ML
Marine drugs12(8)4291-310(2014 Jul)

Bad and Bid - potential background players in preneoplastic to neoplastic shift in human endometrium.
Driak D, Dvorska M, Bolehovska P, Svandova I, Novotny J, Halaska M
Neoplasma61(4)411-5(2014)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Chrysin prevents apoptosis by upregulating the Bcl-2 mRNA expression and downregulating the pro-apoptotic (Bax, Bad) mRNAs in 3-nitropropionic acid induced behavioral despair/mitochondrial dysfunction/striatal apoptosis.
Title: Chrysin exerts neuroprotective effects against 3-Nitropropionic acid induced behavioral despair-Mitochondrial dysfunction and striatal apoptosis via upregulating Bcl-2 gene and downregulating Bax-Bad genes in male wistar rats.

OEC transplantation could effectively improve neurological deficits in TBI rats; the underlying mechanism may be related with their effects on neuroprotection and regeneration induction
Title: Transplantation of olfactory ensheathing cells promotes the recovery of neurological functions in rats with traumatic brain injury associated with downregulation of Bad.

By downregulating ATX-induced activation of Akt/Bad.
Title: Astaxanthin alleviates early brain injury following subarachnoid hemorrhage in rats: possible involvement of Akt/bad signaling.

The early inactivation of PKCepsilon in the ventricle may affect the mitochondrial translocation of Bad and subsequent mitochondrial disruption and apoptosis at late sepsis
Title: Early inactivation of PKC? associates with late mitochondrial translocation of Bad and apoptosis in ventricle of septic rat.

p38MAPK suppresses chronic pancreatitis by upregulating HSP27 expression and downregulating BAD expression.
Title: p38MAPK suppresses chronic pancreatitis by regulating HSP27 and BAD expression.

The following Bad gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Bad cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa06286	NM_022698.1 Latest version!	Rattus norvegicus BCL2-associated agonist of cell death (Bad), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa23833	XM_006230896.3 Latest version!	Rattus norvegicus BCL2-associated agonist of cell death (Bad), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa23834	XM_006230897.3 Latest version!	Rattus norvegicus BCL2-associated agonist of cell death (Bad), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa23835	XM_006230898.3 Latest version!	Rattus norvegicus BCL2-associated agonist of cell death (Bad), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Bad ( NM_022698.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_073189.1 Rattus norvegicus BCL2-associated agonist of cell death (Bad), mRNA.

Price & Availability↑

CloneID	ORa06286
Clone ID Related Accession (Same CDS sequence)	NM_022698.1
Accession Version	NM_022698.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 618bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Rattus norvegicus(Norway rat)
Product	bcl2-associated agonist of cell death
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF279910.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF279910.1, AF031227.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGGAACCC CAAAGCAGCC CTCGCTGGCT CCTGCACACG CCCTAGGCTT GAGGAAGTCC 
GATCCCGGAA TCCGGAGCCT GGGGAGCGAC GCGGGAGGAA GGCGGTGGAG ACCAGCAGCC 
CAGAGTATGT TCCAGATCCC AGAGTTTGAG CCGAGTGAGC AGGAAGACGC TAGTACTACA 
GATAGGGGCC TGGGCCCTAG CCTCACTGAG GACCAGCCAG GTCCCTACCT GGCCCCAGGT 
CTCCTGGGGA GCATCGTTCA GCAGCAGCCG GGACAGGCAG CCAATAACAG TCATCATGGA 
GGCGCTGGGA CTATGGAGAC CCGGAGTCGC CACAGTTCGT ACCCAGCGGG GACTGAGGAA 
GATGAAGGGA TGGAGGAGGA GCTTAGCCCT TTTCGAGGAC GCTCGCGCTC GGCTCCCCCC 
AATCTCTGGG CAGCGCAGCG CTATGGCCGT GAGCTCCGAA GAATGAGCGA TGAATTTGAG 
GGTTCCTTCA AGGGACTTCC TCGCCCAAAG AGCGCAGGCA CTGCAACACA GATGCGACAA 
AGCGCCAGTT GGACGCGCAT TATCCAGTCC TGGTGGGATC GAAATTTGGG GAAAGGAGGC 
TCCACTCCCT CCCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_073189.1
CDS	1..618
Translation	MGTPKQPSLAPAHALGLRKSDPGIRSLGSDAGGRRWRPAAQSMFQIPEFEPSEQEDASTTDRGLGPSLTEDQPGPYLAPGLLGSIVQQQPGQAANNSHHGGAGTMETRSRHSSYPAGTEEDEGMEEELSPFRGRSRSAPPNLWAAQRYGRELRRMSDEFEGSFKGLPRPKSAGTATQMRQSASWTRIIQSWWDRNLGKGGSTPSQ

Target ORF information:

RefSeq Version	NM_022698.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus BCL2-associated agonist of cell death (Bad), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022698.1

ORF Insert Sequence:

ATGGGAACCC CAAAGCAGCC CTCGCTGGCT CCTGCACACG CCCTAGGCTT GAGGAAGTCC 
GATCCCGGAA TCCGGAGCCT GGGGAGCGAC GCGGGAGGAA GGCGGTGGAG ACCAGCAGCC 
CAGAGTATGT TCCAGATCCC AGAGTTTGAG CCGAGTGAGC AGGAAGACGC TAGTACTACA 
GATAGGGGCC TGGGCCCTAG CCTCACTGAG GACCAGCCAG GTCCCTACCT GGCCCCAGGT 
CTCCTGGGGA GCATCGTTCA GCAGCAGCCG GGACAGGCAG CCAATAACAG TCATCATGGA 
GGCGCTGGGA CTATGGAGAC CCGGAGTCGC CACAGTTCGT ACCCAGCGGG GACTGAGGAA 
GATGAAGGGA TGGAGGAGGA GCTTAGCCCT TTTCGAGGAC GCTCGCGCTC GGCTCCCCCC 
AATCTCTGGG CAGCGCAGCG CTATGGCCGT GAGCTCCGAA GAATGAGCGA TGAATTTGAG 
GGTTCCTTCA AGGGACTTCC TCGCCCAAAG AGCGCAGGCA CTGCAACACA GATGCGACAA 
AGCGCCAGTT GGACGCGCAT TATCCAGTCC TGGTGGGATC GAAATTTGGG GAAAGGAGGC 
TCCACTCCCT CCCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Bad ( XM_006230896.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006230958.1 Rattus norvegicus BCL2-associated agonist of cell death (Bad), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa23833
Clone ID Related Accession (Same CDS sequence)	XM_006230896.3
Accession Version	XM_006230896.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 663bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	bcl2-associated agonist of cell death isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006230896.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGAACCC CAAAGCAGCC CTCGCTGGCT CCTGCACACG CCCTAGGCTT GAGGAAGTCC 
GATCCCGGAA TCCGGAGCCT GGGGAGCGAC GCGGGAGGAA GGCGGTGGAG ACCAGCAGCC 
CAGAGTATGT TCCAGATCCC AGAGTTTGAG CCGAGTGAGC AGGAAGACGC TAGTACTACA 
GATAGGGGCC TGGGCCCTAG CCTCACTGAG GACCAGCCAG GTCCCTACCT GGCCCCAGGT 
CTCCTGGGGA GCATCGTTCA GCAGCAGCCG GGACAGGCAG CCAATAACAG TCATCATGGA 
GGCGCTGGGA CTATGGAGAC CCGGAGTCGC CACAGTTCGT ACCCAGCGGG GACTGAGGAA 
GATGAAGGGA TGGAGGAGGA GCTTAGCCCT TTTCGAGGAC GCTCGCGCTC GGCTCCCCCC 
AATCTCTGGG CAGCGCAGCG CTATGGCCGT GAGCTCCGAA GAATGAGCGA TGAATTTGAG 
GGTTCCTTCA AGGGAGAAGA GCTGACGTAC AGCGTTGAGT TCCTTCCGGT GCGTGCAATA 
GCCATGGAGG GGTGGCCCTT GCTTTGGAGT TTTCAAAGTT TTCCACACAC CCTACCCCCT 
ACGCCTCCGG AAGTGGCTAT GTTCCCTCTC CGTTACTGGA CAGCCCTCAG GCGCCTGTGC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006230958.1
CDS	19..681
Translation	MGTPKQPSLAPAHALGLRKSDPGIRSLGSDAGGRRWRPAAQSMFQIPEFEPSEQEDASTTDRGLGPSLTEDQPGPYLAPGLLGSIVQQQPGQAANNSHHGGAGTMETRSRHSSYPAGTEEDEGMEEELSPFRGRSRSAPPNLWAAQRYGRELRRMSDEFEGSFKGEELTYSVEFLPVRAIAMEGWPLLWSFQSFPHTLPPTPPEVAMFPLRYWTALRRLC

Target ORF information:

RefSeq Version	XM_006230896.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus BCL2-associated agonist of cell death (Bad), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006230896.3

ORF Insert Sequence:

ATGGGAACCC CAAAGCAGCC CTCGCTGGCT CCTGCACACG CCCTAGGCTT GAGGAAGTCC 
GATCCCGGAA TCCGGAGCCT GGGGAGCGAC GCGGGAGGAA GGCGGTGGAG ACCAGCAGCC 
CAGAGTATGT TCCAGATCCC AGAGTTTGAG CCGAGTGAGC AGGAAGACGC TAGTACTACA 
GATAGGGGCC TGGGCCCTAG CCTCACTGAG GACCAGCCAG GTCCCTACCT GGCCCCAGGT 
CTCCTGGGGA GCATCGTTCA GCAGCAGCCG GGACAGGCAG CCAATAACAG TCATCATGGA 
GGCGCTGGGA CTATGGAGAC CCGGAGTCGC CACAGTTCGT ACCCAGCGGG GACTGAGGAA 
GATGAAGGGA TGGAGGAGGA GCTTAGCCCT TTTCGAGGAC GCTCGCGCTC GGCTCCCCCC 
AATCTCTGGG CAGCGCAGCG CTATGGCCGT GAGCTCCGAA GAATGAGCGA TGAATTTGAG 
GGTTCCTTCA AGGGAGAAGA GCTGACGTAC AGCGTTGAGT TCCTTCCGGT GCGTGCAATA 
GCCATGGAGG GGTGGCCCTT GCTTTGGAGT TTTCAAAGTT TTCCACACAC CCTACCCCCT 
ACGCCTCCGG AAGTGGCTAT GTTCCCTCTC CGTTACTGGA CAGCCCTCAG GCGCCTGTGC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Bad ( XM_006230897.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006230959.1 Rattus norvegicus BCL2-associated agonist of cell death (Bad), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa23834
Clone ID Related Accession (Same CDS sequence)	XM_006230897.3
Accession Version	XM_006230897.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 537bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	bcl2-associated agonist of cell death isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006230897.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTCCAGA TCCCAGAGTT TGAGCCGAGT GAGCAGGAAG ACGCTAGTAC TACAGATAGG 
GGCCTGGGCC CTAGCCTCAC TGAGGACCAG CCAGGTCCCT ACCTGGCCCC AGGTCTCCTG 
GGGAGCATCG TTCAGCAGCA GCCGGGACAG GCAGCCAATA ACAGTCATCA TGGAGGCGCT 
GGGACTATGG AGACCCGGAG TCGCCACAGT TCGTACCCAG CGGGGACTGA GGAAGATGAA 
GGGATGGAGG AGGAGCTTAG CCCTTTTCGA GGACGCTCGC GCTCGGCTCC CCCCAATCTC 
TGGGCAGCGC AGCGCTATGG CCGTGAGCTC CGAAGAATGA GCGATGAATT TGAGGGTTCC 
TTCAAGGGAG AAGAGCTGAC GTACAGCGTT GAGTTCCTTC CGGTGCGTGC AATAGCCATG 
GAGGGGTGGC CCTTGCTTTG GAGTTTTCAA AGTTTTCCAC ACACCCTACC CCCTACGCCT 
CCGGAAGTGG CTATGTTCCC TCTCCGTTAC TGGACAGCCC TCAGGCGCCT GTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006230959.1
CDS	138..674
Translation	MFQIPEFEPSEQEDASTTDRGLGPSLTEDQPGPYLAPGLLGSIVQQQPGQAANNSHHGGAGTMETRSRHSSYPAGTEEDEGMEEELSPFRGRSRSAPPNLWAAQRYGRELRRMSDEFEGSFKGEELTYSVEFLPVRAIAMEGWPLLWSFQSFPHTLPPTPPEVAMFPLRYWTALRRLC

Target ORF information:

RefSeq Version	XM_006230897.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus BCL2-associated agonist of cell death (Bad), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006230897.3

ORF Insert Sequence:

ATGTTCCAGA TCCCAGAGTT TGAGCCGAGT GAGCAGGAAG ACGCTAGTAC TACAGATAGG 
GGCCTGGGCC CTAGCCTCAC TGAGGACCAG CCAGGTCCCT ACCTGGCCCC AGGTCTCCTG 
GGGAGCATCG TTCAGCAGCA GCCGGGACAG GCAGCCAATA ACAGTCATCA TGGAGGCGCT 
GGGACTATGG AGACCCGGAG TCGCCACAGT TCGTACCCAG CGGGGACTGA GGAAGATGAA 
GGGATGGAGG AGGAGCTTAG CCCTTTTCGA GGACGCTCGC GCTCGGCTCC CCCCAATCTC 
TGGGCAGCGC AGCGCTATGG CCGTGAGCTC CGAAGAATGA GCGATGAATT TGAGGGTTCC 
TTCAAGGGAG AAGAGCTGAC GTACAGCGTT GAGTTCCTTC CGGTGCGTGC AATAGCCATG 
GAGGGGTGGC CCTTGCTTTG GAGTTTTCAA AGTTTTCCAC ACACCCTACC CCCTACGCCT 
CCGGAAGTGG CTATGTTCCC TCTCCGTTAC TGGACAGCCC TCAGGCGCCT GTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Bad ( XM_006230898.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006230960.1 Rattus norvegicus BCL2-associated agonist of cell death (Bad), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa23835
Clone ID Related Accession (Same CDS sequence)	XM_006230898.3
Accession Version	XM_006230898.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 492bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	bcl2-associated agonist of cell death isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006230898.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTCCAGA TCCCAGAGTT TGAGCCGAGT GAGCAGGAAG ACGCTAGTAC TACAGATAGG 
GGCCTGGGCC CTAGCCTCAC TGAGGACCAG CCAGGTCCCT ACCTGGCCCC AGGTCTCCTG 
GGGAGCATCG TTCAGCAGCA GCCGGGACAG GCAGCCAATA ACAGTCATCA TGGAGGCGCT 
GGGACTATGG AGACCCGGAG TCGCCACAGT TCGTACCCAG CGGGGACTGA GGAAGATGAA 
GGGATGGAGG AGGAGCTTAG CCCTTTTCGA GGACGCTCGC GCTCGGCTCC CCCCAATCTC 
TGGGCAGCGC AGCGCTATGG CCGTGAGCTC CGAAGAATGA GCGATGAATT TGAGGGTTCC 
TTCAAGGGAC TTCCTCGCCC AAAGAGCGCA GGCACTGCAA CACAGATGCG ACAAAGCGCC 
AGTTGGACGC GCATTATCCA GTCCTGGTGG GATCGAAATT TGGGGAAAGG AGGCTCCACT 
CCCTCCCAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006230960.1
CDS	134..625
Translation	MFQIPEFEPSEQEDASTTDRGLGPSLTEDQPGPYLAPGLLGSIVQQQPGQAANNSHHGGAGTMETRSRHSSYPAGTEEDEGMEEELSPFRGRSRSAPPNLWAAQRYGRELRRMSDEFEGSFKGLPRPKSAGTATQMRQSASWTRIIQSWWDRNLGKGGSTPSQ

Target ORF information:

RefSeq Version	XM_006230898.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus BCL2-associated agonist of cell death (Bad), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006230898.3

ORF Insert Sequence:

ATGTTCCAGA TCCCAGAGTT TGAGCCGAGT GAGCAGGAAG ACGCTAGTAC TACAGATAGG 
GGCCTGGGCC CTAGCCTCAC TGAGGACCAG CCAGGTCCCT ACCTGGCCCC AGGTCTCCTG 
GGGAGCATCG TTCAGCAGCA GCCGGGACAG GCAGCCAATA ACAGTCATCA TGGAGGCGCT 
GGGACTATGG AGACCCGGAG TCGCCACAGT TCGTACCCAG CGGGGACTGA GGAAGATGAA 
GGGATGGAGG AGGAGCTTAG CCCTTTTCGA GGACGCTCGC GCTCGGCTCC CCCCAATCTC 
TGGGCAGCGC AGCGCTATGG CCGTGAGCTC CGAAGAATGA GCGATGAATT TGAGGGTTCC 
TTCAAGGGAC TTCCTCGCCC AAAGAGCGCA GGCACTGCAA CACAGATGCG ACAAAGCGCC 
AGTTGGACGC GCATTATCCA GTCCTGGTGG GATCGAAATT TGGGGAAAGG AGGCTCCACT 
CCCTCCCAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Chrysin exerts neuroprotective effects against 3-Nitropropionic acid induced behavioral despair-Mitochondrial dysfunction and striatal apoptosis via upregulating Bcl-2 gene and downregulating Bax-Bad genes in male wistar rats.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie84514-525(2016 Dec)
Thangarajan S,Ramachandran S,Krishnamurthy P

Anti-apoptotic effect of San Huang Shel Shin Tang cyclodextrin complex (SHSSTc) on CCl4 -induced hepatotoxicity in rats.
Environmental toxicology31(6)663-70(2016 Jun)
Yang CH,Ting WJ,Shen CY,Hsu HH,Lin YM,Kuo CH,Tsai FJ,Tsai CH,Tsai Y,Huang CY

Astaxanthin alleviates early brain injury following subarachnoid hemorrhage in rats: possible involvement of Akt/bad signaling.
Marine drugs12(8)4291-310(2014 Jul)
Zhang XS,Zhang X,Wu Q,Li W,Zhang QR,Wang CX,Zhou XM,Li H,Shi JX,Zhou ML

Bad and Bid - potential background players in preneoplastic to neoplastic shift in human endometrium.
Neoplasma61(4)411-5(2014)
Driak D,Dvorska M,Bolehovska P,Svandova I,Novotny J,Halaska M

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Bad cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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