Snd1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Snd1
Entrez Gene ID	64635
Full Name	staphylococcal nuclease and tudor domain containing 1
Synonyms	SND p102
General protein information	Preferred Names staphylococcal nuclease and tudor domain containing 1 Names staphylococcal nuclease domain-containing protein 1 100 kDa coactivator p100 co-activator p105 coactivator staphylococcal nuclease domain containing 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 4 Map Location: 4q22

mRNA and Protein(s)

mRNA	Protein	Name
NM_022694.2	NP_073185.2	staphylococcal nuclease domain-containing protein 1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	SND1	XP_532436.3
Mus musculus (house mouse)	Snd1	NP_062750.2
Danio rerio (zebrafish)	snd1	NP_878285.2
Schizosaccharomyces pombe (fission yeast)	snd1	NP_588117.1
Magnaporthe oryzae (rice blast fungus)	MGG_12646	XP_003721166.1
Neurospora crassa	NCU02134	XP_964292.1
Arabidopsis thaliana (thale cress)	Tudor2	NP_200986.1
Oryza sativa (rice)	Os02g0523500	NP_001046985.1
Homo sapiens (human)	SND1	NP_055205.2
Rattus norvegicus (Norway rat)	Snd1	NP_073185.2
Drosophila melanogaster (fruit fly)	Tudor-SN	NP_612021.1
Caenorhabditis elegans (roundworm)	tsn-1	NP_494839.1
Arabidopsis thaliana (thale cress)	Tudor1	NP_196352.2
Bos taurus (cattle)	SND1	NP_991353.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP005672	XP_315689.3
Xenopus tropicalis (tropical clawed frog)	snd1	NP_989183.2
Pan troglodytes (chimpanzee)	SND1	XP_527879.3
	SND1	XP_001088001.2

Gene Ontology
Bibliography

Related articles in PubMed

Tudor-SN-mediated endonucleolytic decay of human cell microRNAs promotes G
Elbarbary RA, Miyoshi K, Myers JR, Du P, Ashton JM, Tian B, Maquat LE
Science (New York, N.Y.)356(6340)859-862(2017 05)

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.
Guo Z, Neilson LJ, Zhong H, Murray PS, Zanivan S, Zaidel-Bar R
Science signaling7(354)rs7(2014 Dec)

Synaptotagmin 11 interacts with components of the RNA-induced silencing complex RISC in clonal pancreatic ?-cells.
Milochau A, Lagr?e V, Benassy MN, Chaignepain S, Papin J, Garcia-Arcos I, Lajoix A, Monterrat C, Coudert L, Schmitter JM, Ochoa B, Lang J
FEBS letters588(14)2217-22(2014 Jun)

Reprogramming of microRNAs by adenosine-to-inosine editing and the selective elimination of edited microRNA precursors in mouse oocytes and preimplantation embryos.
Garc?a-L?pez J, Hourcade Jde D, Del Mazo J
Nucleic acids research41(10)5483-93(2013 May)

Elevated transcriptional co-activator p102 mediates angiotensin II type 1 receptor up-regulation and extracellular matrix overproduction in the high glucose-treated rat glomerular mesangial cells and isolated glomeruli.
Wang Z, Ni J, Shao D, Liu J, Shen Y, Zhou L, Huang Y, Yu C, Wang J, Xue H, Lu L
European journal of pharmacology702(1-3)208-17(2013 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Overproduction of reactive oxygen species at the early stage of high glucose incubation stimulates p102 synthesis, which in turn up-regulates AT1 receptor expression.
Title: Elevated transcriptional co-activator p102 mediates angiotensin II type 1 receptor up-regulation and extracellular matrix overproduction in the high glucose-treated rat glomerular mesangial cells and isolated glomeruli.

Absence of TATA box and location and reverse orientation of the CCAAT boxes in the promoter region strongly suggest a role for NF-Y in the regulation of transcription of SND p102 gene.
Title: Isolation and characterization of the rat SND p102 gene promoter: putative role for nuclear factor-Y in regulation of transcription.

cells overexpressing SND p102 secreted phospholipid-rich lipoproteins
Title: Overexpression of SND p102, a rat homologue of p100 coactivator, promotes the secretion of lipoprotein phospholipids in primary hepatocytes.

The following Snd1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Snd1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa06270	NM_022694.2 Latest version!	Rattus norvegicus staphylococcal nuclease and tudor domain containing 1 (Snd1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$531.30 $759.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Snd1 ( NM_022694.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_073185.2 Rattus norvegicus staphylococcal nuclease and tudor domain containing 1 (Snd1), mRNA.

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CloneID	ORa06270
Clone ID Related Accession (Same CDS sequence)	NM_022694.2
Accession Version	NM_022694.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2730bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-18
Organism	Rattus norvegicus(Norway rat)
Product	staphylococcal nuclease domain-containing protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC072471.1. On Oct 9, 2005 this sequence version replaced NM_022694.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC072471.1, AY697864.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGCCTCCG CGCAGAGCAG CGGCTCCTCC GGGGGACCCG CGGTCCCCAC CGTGCAACGG 
GGCATCGTCA AGATGGTCCT CTCTGGGTGT GCCATCATTG TCCGAGGGCA GCCCCGGGGC 
GGTCCGCCTC CAGAGAGGCA GATCAACCTC AGCAACATTC GAGCTGGAAA TCTCGCCCGT 
CGGGCAGCTG CTACGCAACC AGATGGGAAA GATACCCCAG ATGAGCCCTG GGCATTTCCT 
GCTAGAGAGT TCCTTCGCAA GAAGCTGATT GGGAAGGAAG TCTGTTTCAC GATAGAAAAC 
AAGACTCCCC AAGGACGAGA GTATGGAATG ATCTACCTTG GAAAAGATAC TAATGGGGAA 
AACATTGCAG AGTCGCTAGT CGCAGAAGGC TTGGCCTCCC GGAGAGAAGG CATGAGAGCC 
AATAACCCAG AGCAGAACCG GCTTTCAGAA TGCGAGGAAC AAGCAAAGGC ATCGAAGAAA 
GGGATGTGGA GTGAGGGGAA CGGGTCACAC ACCATCCGGG ACCTCAAGTA CACCATTGAG 
AACCCAAGGC ACTTTGTGGA CTCACACCAC CAGAAGCCTG TCAATGCTAT CATTGAGCAT 
GTTCGAGACG GCAGTGTGGT CCGGGCCCTG CTCCTTCCGG ATCACTACCT TGTTACCGTC 
ATGCTGTCAG GGATTAAGTG CCCAACCTTT CGTCGAGAAA CAGATGGTAG TGAAACACCA 
GAGCCCTTCG CTGCAGAAGC CAAGTTTTTC ACGGAGTCTC GACTGCTTCA GAGAGATGTT 
CAGATCATTC TGGAGAGCTG CCATAATCAG AACATTCTGG GCACCATCCT TCATCCAAAT 
GGTAACATCA CTGAACTCCT CCTGAAGGAA GGTTTTGCCC GCTGTGTGGA CTGGTCAATT 
GCAGTTTACA CCCGGGGTGC AGAAAAGCTG AGGGCAGCTG AGAGGTTTGC CAAGGAGCGT 
AGGCTGAGAA TATGGAGAGA CTATGTGCCT CCTACTGCTA ATTTGGACCA AAAGGACAAG 
CAGTTTGTTG CCAAGGTAAT GCAGGTTTTG AATGCTGATG CCATTGTTGT GAAGCTGAAT 
TCTGGAGACT ACAAGACCAT CCACCTGTCA AGCATCCGAC CACCAAGGTT GGAGGGAGAC 
AACATACAGG ATAAGAATAA GAAGCTCCGG CCCCTGTATG ACATCCCCTA CATGTTTGAG 
GCCCGGGAAT TCCTTCGCAA AAAGCTCATT GGGAAGAAGG TCAGTGTGAC TGTGGACTAC 
ATTAGACCAG CCAGCCCAGC CACAGAAACA GTGCCTGCCT TTTCTGAGCG TACCTGTGCC 
ACTGTCACCA TTGGAGGAAT AAACATTGCT GAGGCCCTTG TCAGCAAAGG CCTAGCCACA 
GTGATCAGAT ACCGGCAGGA TGATGACCAG AGATCTTCAC ACTATGATGA GCTGCTGGCT 
GCAGAGGCCA GAGCGATTAA GAATGGCAAA GGATTGCACA GCAAGAAGGA AGTGCCCATC 
CACCGAGTTG CAGACATTTC TGGGGACACC CAGAAAGCAA AGCAGTTCCT GCCCTTTCTT 
CAGCGCGCAG GCCGTTCTGA GGCTGTGGTG GAGTATGTCT TCAGTGGCTC TCGCCTCAAG 
CTCTACTTAC CTAAGGAGAC CTGTCTCATC ACCTTCCTGC TGGCAGGCAT TGAATGTCCC 
AGAGGAGCAC GAAATCTCCC AGGCTTGGTG CAGGAAGGAG AGCCATTCAG TGAGGAAGCC 
ACACTTTTCA CCAAGGAACT AGTGCTGCAG CGAGAGGTGG AGGTGGAGGT AGAGAGCATG 
GATAAGGCTG GCAACTTCAT TGGCTGGCTA CACATGGATG GGGCTAACCT GTCTGTCTTG 
CTGGTGGAGC ACGCGCTCTC CAAGGTCCAC TTCACTGCTG AGCGCAGCGC CTACTATAAG 
CCTCTCCTGT CTGCTGAGGA AGCTGCCAAG CAGAGGAAAG AGAAGGTCTG GGCCCACTAT 
GAGGAGCAGC CTGTGGAGGA GGTAATGCCT GTACTGGAAG AGAAGGAGCG CTCGGCCAGC 
TACAAGCCAG TGTTTGTGAC CGAGATCACA GATGACCTGC ATTTCTATGT GCAAGATGTG 
GAGACTGGCA CCCAGCTGGA AAAACTGATG GAGAACATGC GCAGTGACAT CTCCAGCCAC 
CCTCCTGTTG AGGGTGCCTA CGCCCCACGC CGGGGAGAGT TCTGCATTGC CAAATTTGTA 
GATGGAGAAT GGTACCGCGC CCGGGTAGAA AAAGTGGAGT CCCCTGCCAA AGTGCATGTC 
TTCTACATCG ACTATGGCAA TAGAGAGATC CTGCCATCCA CCCGCCTGGG TGCCCTACCA 
CCTGCCTTCA GCACTCGCGT GTTGCCAGCT CAAGCCACAG AGTATGCCTT CGCCTTCATC 
CAGGTGCCCC AAGATGAGGA CGCTCGCACA GATGCTGTGG ACAGTGTGGT GCGGGACATC 
CAAAACACTC AGTGCCTGCT CAACGTGGAG CACCTGAGTG CCAGCTGCCC CCATGTCACT 
CTGCAGTTTG CGGATTCCAA AGGTGATGTG GGGCTGGGCC TGGTGAAGGA AGGACTCGTC 
ATGGTAGAAG TTCGGAAGGA GAAGCAGTTC CAGAAAGTGA TCACAGAGTA CCTGAATGCC 
CAGGAATCAG CCAAGAGTGC CAGGCTGAAC CTGTGGCGCT ATGGCGACTT CCGAGCTGAC 
GATGCTGATG AGTTTGGCTA CAGTCGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_073185.2
CDS	202..2931
Translation	MASAQSSGSSGGPAVPTVQRGIVKMVLSGCAIIVRGQPRGGPPPERQINLSNIRAGNLARRAAATQPDGKDTPDEPWAFPAREFLRKKLIGKEVCFTIENKTPQGREYGMIYLGKDTNGENIAESLVAEGLASRREGMRANNPEQNRLSECEEQAKASKKGMWSEGNGSHTIRDLKYTIENPRHFVDSHHQKPVNAIIEHVRDGSVVRALLLPDHYLVTVMLSGIKCPTFRRETDGSETPEPFAAEAKFFTESRLLQRDVQIILESCHNQNILGTILHPNGNITELLLKEGFARCVDWSIAVYTRGAEKLRAAERFAKERRLRIWRDYVPPTANLDQKDKQFVAKVMQVLNADAIVVKLNSGDYKTIHLSSIRPPRLEGDNIQDKNKKLRPLYDIPYMFEAREFLRKKLIGKKVSVTVDYIRPASPATETVPAFSERTCATVTIGGINIAEALVSKGLATVIRYRQDDDQRSSHYDELLAAEARAIKNGKGLHSKKEVPIHRVADISGDTQKAKQFLPFLQRAGRSEAVVEYVFSGSRLKLYLPKETCLITFLLAGIECPRGARNLPGLVQEGEPFSEEATLFTKELVLQREVEVEVESMDKAGNFIGWLHMDGANLSVLLVEHALSKVHFTAERSAYYKPLLSAEEAAKQRKEKVWAHYEEQPVEEVMPVLEEKERSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRSDISSHPPVEGAYAPRRGEFCIAKFVDGEWYRARVEKVESPAKVHVFYIDYGNREILPSTRLGALPPAFSTRVLPAQATEYAFAFIQVPQDEDARTDAVDSVVRDIQNTQCLLNVEHLSASCPHVTLQFADSKGDVGLGLVKEGLVMVEVRKEKQFQKVITEYLNAQESAKSARLNLWRYGDFRADDADEFGYSR

Target ORF information:

RefSeq Version	NM_022694.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus staphylococcal nuclease and tudor domain containing 1 (Snd1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022694.2

ORF Insert Sequence:

ATGGCCTCCG CGCAGAGCAG CGGCTCCTCC GGGGGACCCG CGGTCCCCAC CGTGCAACGG 
GGCATCGTCA AGATGGTCCT CTCTGGGTGT GCCATCATTG TCCGAGGGCA GCCCCGGGGC 
GGTCCGCCTC CAGAGAGGCA GATCAACCTC AGCAACATTC GAGCTGGAAA TCTCGCCCGT 
CGGGCAGCTG CTACGCAACC AGATGGGAAA GATACCCCAG ATGAGCCCTG GGCATTTCCT 
GCTAGAGAGT TCCTTCGCAA GAAGCTGATT GGGAAGGAAG TCTGTTTCAC GATAGAAAAC 
AAGACTCCCC AAGGACGAGA GTATGGAATG ATCTACCTTG GAAAAGATAC TAATGGGGAA 
AACATTGCAG AGTCGCTAGT CGCAGAAGGC TTGGCCTCCC GGAGAGAAGG CATGAGAGCC 
AATAACCCAG AGCAGAACCG GCTTTCAGAA TGCGAGGAAC AAGCAAAGGC ATCGAAGAAA 
GGGATGTGGA GTGAGGGGAA CGGGTCACAC ACCATCCGGG ACCTCAAGTA CACCATTGAG 
AACCCAAGGC ACTTTGTGGA CTCACACCAC CAGAAGCCTG TCAATGCTAT CATTGAGCAT 
GTTCGAGACG GCAGTGTGGT CCGGGCCCTG CTCCTTCCGG ATCACTACCT TGTTACCGTC 
ATGCTGTCAG GGATTAAGTG CCCAACCTTT CGTCGAGAAA CAGATGGTAG TGAAACACCA 
GAGCCCTTCG CTGCAGAAGC CAAGTTTTTC ACGGAGTCTC GACTGCTTCA GAGAGATGTT 
CAGATCATTC TGGAGAGCTG CCATAATCAG AACATTCTGG GCACCATCCT TCATCCAAAT 
GGTAACATCA CTGAACTCCT CCTGAAGGAA GGTTTTGCCC GCTGTGTGGA CTGGTCAATT 
GCAGTTTACA CCCGGGGTGC AGAAAAGCTG AGGGCAGCTG AGAGGTTTGC CAAGGAGCGT 
AGGCTGAGAA TATGGAGAGA CTATGTGCCT CCTACTGCTA ATTTGGACCA AAAGGACAAG 
CAGTTTGTTG CCAAGGTAAT GCAGGTTTTG AATGCTGATG CCATTGTTGT GAAGCTGAAT 
TCTGGAGACT ACAAGACCAT CCACCTGTCA AGCATCCGAC CACCAAGGTT GGAGGGAGAC 
AACATACAGG ATAAGAATAA GAAGCTCCGG CCCCTGTATG ACATCCCCTA CATGTTTGAG 
GCCCGGGAAT TCCTTCGCAA AAAGCTCATT GGGAAGAAGG TCAGTGTGAC TGTGGACTAC 
ATTAGACCAG CCAGCCCAGC CACAGAAACA GTGCCTGCCT TTTCTGAGCG TACCTGTGCC 
ACTGTCACCA TTGGAGGAAT AAACATTGCT GAGGCCCTTG TCAGCAAAGG CCTAGCCACA 
GTGATCAGAT ACCGGCAGGA TGATGACCAG AGATCTTCAC ACTATGATGA GCTGCTGGCT 
GCAGAGGCCA GAGCGATTAA GAATGGCAAA GGATTGCACA GCAAGAAGGA AGTGCCCATC 
CACCGAGTTG CAGACATTTC TGGGGACACC CAGAAAGCAA AGCAGTTCCT GCCCTTTCTT 
CAGCGCGCAG GCCGTTCTGA GGCTGTGGTG GAGTATGTCT TCAGTGGCTC TCGCCTCAAG 
CTCTACTTAC CTAAGGAGAC CTGTCTCATC ACCTTCCTGC TGGCAGGCAT TGAATGTCCC 
AGAGGAGCAC GAAATCTCCC AGGCTTGGTG CAGGAAGGAG AGCCATTCAG TGAGGAAGCC 
ACACTTTTCA CCAAGGAACT AGTGCTGCAG CGAGAGGTGG AGGTGGAGGT AGAGAGCATG 
GATAAGGCTG GCAACTTCAT TGGCTGGCTA CACATGGATG GGGCTAACCT GTCTGTCTTG 
CTGGTGGAGC ACGCGCTCTC CAAGGTCCAC TTCACTGCTG AGCGCAGCGC CTACTATAAG 
CCTCTCCTGT CTGCTGAGGA AGCTGCCAAG CAGAGGAAAG AGAAGGTCTG GGCCCACTAT 
GAGGAGCAGC CTGTGGAGGA GGTAATGCCT GTACTGGAAG AGAAGGAGCG CTCGGCCAGC 
TACAAGCCAG TGTTTGTGAC CGAGATCACA GATGACCTGC ATTTCTATGT GCAAGATGTG 
GAGACTGGCA CCCAGCTGGA AAAACTGATG GAGAACATGC GCAGTGACAT CTCCAGCCAC 
CCTCCTGTTG AGGGTGCCTA CGCCCCACGC CGGGGAGAGT TCTGCATTGC CAAATTTGTA 
GATGGAGAAT GGTACCGCGC CCGGGTAGAA AAAGTGGAGT CCCCTGCCAA AGTGCATGTC 
TTCTACATCG ACTATGGCAA TAGAGAGATC CTGCCATCCA CCCGCCTGGG TGCCCTACCA 
CCTGCCTTCA GCACTCGCGT GTTGCCAGCT CAAGCCACAG AGTATGCCTT CGCCTTCATC 
CAGGTGCCCC AAGATGAGGA CGCTCGCACA GATGCTGTGG ACAGTGTGGT GCGGGACATC 
CAAAACACTC AGTGCCTGCT CAACGTGGAG CACCTGAGTG CCAGCTGCCC CCATGTCACT 
CTGCAGTTTG CGGATTCCAA AGGTGATGTG GGGCTGGGCC TGGTGAAGGA AGGACTCGTC 
ATGGTAGAAG TTCGGAAGGA GAAGCAGTTC CAGAAAGTGA TCACAGAGTA CCTGAATGCC 
CAGGAATCAG CCAAGAGTGC CAGGCTGAAC CTGTGGCGCT ATGGCGACTT CCGAGCTGAC 
GATGCTGATG AGTTTGGCTA CAGTCGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Tudor-SN-mediated endonucleolytic decay of human cell microRNAs promotes G
Science (New York, N.Y.)356(6340)859-862(2017 05)
Elbarbary RA,Miyoshi K,Myers JR,Du P,Ashton JM,Tian B,Maquat LE

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.
Science signaling7(354)rs7(2014 Dec)
Guo Z,Neilson LJ,Zhong H,Murray PS,Zanivan S,Zaidel-Bar R

Synaptotagmin 11 interacts with components of the RNA-induced silencing complex RISC in clonal pancreatic ?-cells.
FEBS letters588(14)2217-22(2014 Jun)
Milochau A,Lagr?e V,Benassy MN,Chaignepain S,Papin J,Garcia-Arcos I,Lajoix A,Monterrat C,Coudert L,Schmitter JM,Ochoa B,Lang J

Reprogramming of microRNAs by adenosine-to-inosine editing and the selective elimination of edited microRNA precursors in mouse oocytes and preimplantation embryos.
Nucleic acids research41(10)5483-93(2013 May)
Garc?a-L?pez J,Hourcade Jde D,Del Mazo J

Elevated transcriptional co-activator p102 mediates angiotensin II type 1 receptor up-regulation and extracellular matrix overproduction in the high glucose-treated rat glomerular mesangial cells and isolated glomeruli.
European journal of pharmacology702(1-3)208-17(2013 Feb)
Wang Z,Ni J,Shao D,Liu J,Shen Y,Zhou L,Huang Y,Yu C,Wang J,Xue H,Lu L

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Snd1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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