Adnp cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Adnp
Entrez Gene ID	64622
Full Name	activity-dependent neuroprotector homeobox
General protein information	Preferred Names activity-dependent neuroprotector homeobox Names activity-dependent neuroprotector homeobox protein NAP peptide activity-dependent neuroprotective protein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3q42
Summary	This gene encodes a member of a protein family characterized by nine zinc finger motifs followed by a homeobox domain. In vitro studies demonstrate that the encoded protein interacts with the brahma-related gene1-associated or hBRM factors (BAF) gene expression regulating complex, components of the protein translation machinery, and microtubule-associated proteins. This gene has been implicated in neuroprotection through various processes that include chromatin remodeling, splicing, cytoskeletal reorganization, and autophagy. Homozygous mutant knockout mice display embryonic lethality with defects in neural tube closure. [provided by RefSeq, Nov 2016].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001347532.1	NP_001334461.1	activity-dependent neuroprotector homeobox protein

Pathways from BioSystems

Homologies

	ADNP	XP_001094971.2
Canis lupus familiaris (dog)	ADNP	XP_853284.2
Homo sapiens (human)	ADNP	NP_001269460.1
Pan troglodytes (chimpanzee)	ADNP	XP_001168448.1
Xenopus tropicalis (tropical clawed frog)	adnp	XP_002933199.1
Bos taurus (cattle)	ADNP	NP_001192960.1
Danio rerio (zebrafish)	adnp	XP_002666520.1
Mus musculus (house mouse)	Adnp	NP_033758.2
Rattus norvegicus (Norway rat)	Adnp	NP_073172.2
Gallus gallus (chicken)	ADNP	XP_004947324.1

Gene Ontology
Bibliography

Related articles in PubMed

Alterations in Activity-Dependent Neuroprotective Protein in Sporadic and Experimental Parkinson's Disease.
Chu Y, Morfini GA, Kordower JH
Journal of Parkinson's disease6(1)77-97(2016)

The NAP motif of activity-dependent neuroprotective protein (ADNP) regulates dendritic spines through microtubule end binding proteins.
Oz S, Kapitansky O, Ivashco-Pachima Y, Malishkevich A, Giladi E, Skalka N, Rosin-Arbesfeld R, Mittelman L, Segev O, Hirsch JA, Gozes I
Molecular psychiatry19(10)1115-24(2014 Oct)

Involvement of PACAP/ADNP signaling in the resistance to cell death in malignant peripheral nerve sheath tumor (MPNST) cells.
Castorina A, Giunta S, Scuderi S, D'Agata V
Journal of molecular neuroscience : MN48(3)674-83(2012 Nov)

The ADNP derived peptide, NAP modulates the tubulin pool: implication for neurotrophic and neuroprotective activities.
Oz S, Ivashko-Pachima Y, Gozes I
PloS one7(12)e51458(2012)

Nitric oxide regulates activity-dependent neuroprotective protein (ADNP) in the dentate gyrus of the rodent model of kainic acid-induced seizure.
Cosgrave AS, McKay JS, Morris R, Quinn JP, Thippeswamy T
Journal of molecular neuroscience : MN39(1-2)9-21(2009 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These findings demonstrate that the down-regulation of protein ADNP is an early pathological alteration and may contribute to dopaminergic neurodegeneration in Parkinson's disease
Title: Alterations in Activity-Dependent Neuroprotective Protein in Sporadic and Experimental Parkinson's Disease.

the newly identified shared microtubule target of NAP/ADNP is directly implicated in synaptic plasticity, explaining the breadth and efficiency of neuroprotective/neurotrophic capacities
Title: The NAP motif of activity-dependent neuroprotective protein (ADNP) regulates dendritic spines through microtubule end binding proteins.

An endogenous PACAP-mediated ADNP signaling system increases malignant peripheral nerve sheath tumor cell resistance to hydrogen-peroxide-induced death upon serum starvation.
Title: Involvement of PACAP/ADNP signaling in the resistance to cell death in malignant peripheral nerve sheath tumor (MPNST) cells.

NAP is an ADNP derived peptide that modulates the tubulin pool in mice and rats
Title: The ADNP derived peptide, NAP modulates the tubulin pool: implication for neurotrophic and neuroprotective activities.

Results suggest that nitric oxide regulates activity-dependent neuroprotective protein in the dentate gyrus under both basal and pathophysiological conditions.
Title: Nitric oxide regulates activity-dependent neuroprotective protein (ADNP) in the dentate gyrus of the rodent model of kainic acid-induced seizure.

The following Adnp gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Adnp cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa39868	NM_001347532.1 Latest version!	Rattus norvegicus activity-dependent neuroprotector homeobox (Adnp), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Adnp ( NM_001347532.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001334461.1 Rattus norvegicus activity-dependent neuroprotector homeobox (Adnp), mRNA.

Price & Availability↑

CloneID	ORa39868
Clone ID Related Accession (Same CDS sequence)	NM_001347532.1
Accession Version	NM_001347532.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3312bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-28
Organism	Rattus norvegicus(Norway rat)
Product	activity-dependent neuroprotector homeobox protein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07054628.1 and AABR07054626.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BF523190.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906348 [ECO:0000348] ##Evidence-Data-END##

ATGTTCCAAC TTCCTGTCAA CAATCTTGGC AGTTTAAGAA AAGCCCGGAA AACTGTGAAA 
AAAATACTTA GTGACATTGG GTTGGAATAC TGTAAAGAAC ATATAGAAGA TTTTAAACAG 
TTTGAACCTA ATGACTTTTA TTTGAAAAAC ACTACATGGG AGGATGTAGG ACTGTGGGAC 
CCTTCTCTTA CAAAAAATCA GGACTATCGG ACAAAACCTT TCTGCTGCAG TGCTTGTCCG 
TTTTCCTCAA AATTCTTCTC TGCCTACAAA AGTCATTTCC GGAATGTCCA TAGTGAAGAC 
TTTGAAAATA GGATTCTCCT TAACTGCCCT TACTGTACCT TCAATGCAGA TAAAAAGACT 
TTGGAAACAC ACATTAAAAT ATTTCATGCT CCAAACTCCA GCGCACCAAG TAGCAGCCTC 
AGCACTTTCA AAGATAAAAA CAAAAACGAT GGCCTTAAAC CTAAGCAGGC TGACAATGTA 
GAGCAAGCCG TGTATTACTG CAAGAAGTGC ACTTACCGAG ACCCTCTCTA TGAGATCGTC 
AGGAAGCACA TCTACAGGGA ACATTTTCAA CACGTGGCAG CACCCTACAT AGCAAAGGCA 
GGAGAAAAAT CACTCAATGG TGCAGTCTCT CTGGGCACAA ATGCCCGAGA AGAGTGTAAC 
ATCCACTGCA AGCGATGCCT TTTCATGCCC AAATCCTATG AAGCTTTGGT ACAGCATGTC 
ATTGAAGACC ATGAACGGAT AGGCTATCAG GTCACTGCCA TGATTGGACA CACAAATGTT 
GTAGTTCCCC GAGCCAAACC CTTAATGCTA ATTGCTCCCA AACCTCAAGA AAAAAAGAGC 
ATGGGACTCC CACCAAGAAT CAGTTCTCTT GCTTCTGGAA ATGTCCGGTC TTTGCCATCA 
CAGCAGATGG TGAACCGATT GTCAATACCA AAGCCCAATT TAAATTCAAC GGGAGTCAAC 
ATGATGTCCA ATGTTCACCT GCAGCAAAAC AACTATGGAG TGAAATCTGT GGGCCAGAGC 
TATGGTGTTG GCCAGTCAGT GAGGCTGGGG CTAGGTGGCA ATGCTCCAGT TTCCATCCCT 
CAACAGTCTC AGTCTGTCAA ACAGTTACTT CCAAGTGGAA ATGGGAGGTC CTACGGGCTA 
GGTGCTGAGC AGAGGCCCCC GGCAGCTGCC AGGTATTCCC TGCAGACTGC CAACACGTCC 
TCTCTACCCC CAGGCCAGGT AAAGTCTCCC TCTGTGTCTC AGTCACAGGC ATCTAGAGTA 
TTAGGTCAGT CCAGTTCTAA ACCTCCACCA GCAGCCACAG GCCCTCCTCC AAGCAACCAT 
TGTGCCACTC AGAAGTGGAA AATATGTACA ATCTGTAATG AGCTTTTTCC TGAGAATGTC 
TACAGTGTTC ACTTCGAAAA GGAACATAAA GCGGAGAAAG TTCCAGCAGT AGCTAACTAC 
ATTATGAAAA TACACAATTT TACTAGCAAA TGCCTCTATT GTAATCGCTA TCTGCCCACA 
GATACCCTGC TCAACCATAT GTTAATTCAT GGTCTGTCTT GTCCATATTG CCGTTCCACC 
TTCAATGATG TGGAGAAGAT GGCAGCACAC ATGCGAATGG TTCATATTGA TGAGGAGATG 
GGGCCTAAAA CGGATTCTAC CTTGAGCTTT GATTTGACAT TGCAACAGGG CAGTCACACC 
AACATTCATC TCCTGGTGAC CACATACAAC CTGAGAGATG CCCCGGCTGA ATCAGTTGCT 
TACCATGCCC AAAATAATGC CCCAGTTCCT CCAAAGCCAC AACCAAAAGT TCAGGAAAAA 
GCTGATGTCC CTGTTAAAAG TTCACCTCAA GCTGCAGTGC CCTATAAAAA AGATGTGGGG 
AAGACCCTCT GCCCTCTCTG CTTTTCAATC CTAAAAGGAC CCATATCTGA TGCACTTGCA 
CATCATTTAC GAGAAAGACA CCAAGTTATT CAGACAGTTC ATCCGGTTGA GAAAAAGCTA 
ACTTACAAAT GTATCCATTG CCTTGGTGTG TATACTAGCA ACATGACAGC CTCAACCATC 
ACTCTGCATC TAGTCCACTG CAGGGGTGTT GGAAAGACCC AGAATGGCCA GGACAAGACA 
AACGCACCTT CTCGGCTCAA TCAGTCTCCA GGCCTGGCCC CTGTGAAGCG CACATATGAG 
CAAATGGAGT TTCCACTGCT AAAGAAGCGA AAGCTGGAGG ATGAGAATGA CTCCCCAGGC 
TGCTTTGAAG AGAAGCCGGA AGAGCCTGTT GTTTTAGCTT TAGACCCCAA GGGTCATGAA 
GATGATTCAT ATGAAGCTAG GAAAAGCTTT CTCACAAAGT ACTTCAACAA ACAGCCCTAT 
CCCACTAGGA GAGAAATTGA GAAGTTAGCT GCCAGTCTGT GGCTGTGGAA GAGCGACATT 
GCCTCCCATT TCAGTAACAA GAGGAAGAAG TGTGTCCGTG ACTGTGAGAA GTATAAGCCT 
GGTGTGCTGC TAGGTTTTAA CATGAAAGAA TTAAATAAAG TCAAACATGA GATGGATTTT 
GATGCTGAGT GGCTATTTGA AAATCATGAC GAGAAAGCCT CAAGAGTCAA TGCTAGCAAG 
ACTGTTGACA AAAAGCTTAA CCTTGGGAAA GAAGATGACA GCTTCTCAGA TAGTTTTGAA 
CATTTGGAAG AAGAATCCAA TGGAAGCGGC GGCCCTTTTG ACCCTGTCTT TGAAGTTGAG 
CCTAAAATTC CCAGTGATAA TGCAGAGGAG CCTGTGCCGA AGGTAATTCC TGAAGGTGCT 
TTGGAGTCTG AGAAGCTAGA CCAAAAAGAG GAGGAGGATG GTTCAAAATA TGAAACCATC 
CATTTGACTG AGGAACGAGC CAAACTGATG CATGATGCCT CTGATAGTGA GGTAGACCAA 
GATGATGTGG TTGAGTGGAA AGATGGTGCT TCGCCATCTG AGAGTGGGCC TGGTTCCCGA 
CAGGTCTCAG ACTTTGAGGA TAATACATGT GAAATGAAAC CAGGAACCTG GTCTGATGAG 
TCTTCCCAGA GTGAAGACGC AAGGAGCAGT AAGCCGGCTG CCAAAAAAAA GGCTACAGTG 
CAAGATGACA CAGAGCAGTT GAAATGGAAG AATAGTTCCT ATGGAAAAGT TGAAGGGTTT 
TGGTCCAAGG ACCAGTCACA GTGGGAAAAT GCATCTGAGA ATGCAGAGCG CTTACCAAAC 
CCACAGATTG AGTGGCAGAA TAGCACAATT GACAGTGAGG ATGGGGAGCA GTTTGACAGC 
ATGACCGATG GAGTTGCCGA TCCCATGCAC GGCAGCTTAA CTGGAGTGAA GCTGAGCAGC 
CAGCAAGCCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001334461.1
CDS	1605..4916
Translation	MFQLPVNNLGSLRKARKTVKKILSDIGLEYCKEHIEDFKQFEPNDFYLKNTTWEDVGLWDPSLTKNQDYRTKPFCCSACPFSSKFFSAYKSHFRNVHSEDFENRILLNCPYCTFNADKKTLETHIKIFHAPNSSAPSSSLSTFKDKNKNDGLKPKQADNVEQAVYYCKKCTYRDPLYEIVRKHIYREHFQHVAAPYIAKAGEKSLNGAVSLGTNAREECNIHCKRCLFMPKSYEALVQHVIEDHERIGYQVTAMIGHTNVVVPRAKPLMLIAPKPQEKKSMGLPPRISSLASGNVRSLPSQQMVNRLSIPKPNLNSTGVNMMSNVHLQQNNYGVKSVGQSYGVGQSVRLGLGGNAPVSIPQQSQSVKQLLPSGNGRSYGLGAEQRPPAAARYSLQTANTSSLPPGQVKSPSVSQSQASRVLGQSSSKPPPAATGPPPSNHCATQKWKICTICNELFPENVYSVHFEKEHKAEKVPAVANYIMKIHNFTSKCLYCNRYLPTDTLLNHMLIHGLSCPYCRSTFNDVEKMAAHMRMVHIDEEMGPKTDSTLSFDLTLQQGSHTNIHLLVTTYNLRDAPAESVAYHAQNNAPVPPKPQPKVQEKADVPVKSSPQAAVPYKKDVGKTLCPLCFSILKGPISDALAHHLRERHQVIQTVHPVEKKLTYKCIHCLGVYTSNMTASTITLHLVHCRGVGKTQNGQDKTNAPSRLNQSPGLAPVKRTYEQMEFPLLKKRKLEDENDSPGCFEEKPEEPVVLALDPKGHEDDSYEARKSFLTKYFNKQPYPTRREIEKLAASLWLWKSDIASHFSNKRKKCVRDCEKYKPGVLLGFNMKELNKVKHEMDFDAEWLFENHDEKASRVNASKTVDKKLNLGKEDDSFSDSFEHLEEESNGSGGPFDPVFEVEPKIPSDNAEEPVPKVIPEGALESEKLDQKEEEDGSKYETIHLTEERAKLMHDASDSEVDQDDVVEWKDGASPSESGPGSRQVSDFEDNTCEMKPGTWSDESSQSEDARSSKPAAKKKATVQDDTEQLKWKNSSYGKVEGFWSKDQSQWENASENAERLPNPQIEWQNSTIDSEDGEQFDSMTDGVADPMHGSLTGVKLSSQQA

Target ORF information:

RefSeq Version	NM_001347532.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus activity-dependent neuroprotector homeobox (Adnp), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001347532.1

ORF Insert Sequence:

ATGTTCCAAC TTCCTGTCAA CAATCTTGGC AGTTTAAGAA AAGCCCGGAA AACTGTGAAA 
AAAATACTTA GTGACATTGG GTTGGAATAC TGTAAAGAAC ATATAGAAGA TTTTAAACAG 
TTTGAACCTA ATGACTTTTA TTTGAAAAAC ACTACATGGG AGGATGTAGG ACTGTGGGAC 
CCTTCTCTTA CAAAAAATCA GGACTATCGG ACAAAACCTT TCTGCTGCAG TGCTTGTCCG 
TTTTCCTCAA AATTCTTCTC TGCCTACAAA AGTCATTTCC GGAATGTCCA TAGTGAAGAC 
TTTGAAAATA GGATTCTCCT TAACTGCCCT TACTGTACCT TCAATGCAGA TAAAAAGACT 
TTGGAAACAC ACATTAAAAT ATTTCATGCT CCAAACTCCA GCGCACCAAG TAGCAGCCTC 
AGCACTTTCA AAGATAAAAA CAAAAACGAT GGCCTTAAAC CTAAGCAGGC TGACAATGTA 
GAGCAAGCCG TGTATTACTG CAAGAAGTGC ACTTACCGAG ACCCTCTCTA TGAGATCGTC 
AGGAAGCACA TCTACAGGGA ACATTTTCAA CACGTGGCAG CACCCTACAT AGCAAAGGCA 
GGAGAAAAAT CACTCAATGG TGCAGTCTCT CTGGGCACAA ATGCCCGAGA AGAGTGTAAC 
ATCCACTGCA AGCGATGCCT TTTCATGCCC AAATCCTATG AAGCTTTGGT ACAGCATGTC 
ATTGAAGACC ATGAACGGAT AGGCTATCAG GTCACTGCCA TGATTGGACA CACAAATGTT 
GTAGTTCCCC GAGCCAAACC CTTAATGCTA ATTGCTCCCA AACCTCAAGA AAAAAAGAGC 
ATGGGACTCC CACCAAGAAT CAGTTCTCTT GCTTCTGGAA ATGTCCGGTC TTTGCCATCA 
CAGCAGATGG TGAACCGATT GTCAATACCA AAGCCCAATT TAAATTCAAC GGGAGTCAAC 
ATGATGTCCA ATGTTCACCT GCAGCAAAAC AACTATGGAG TGAAATCTGT GGGCCAGAGC 
TATGGTGTTG GCCAGTCAGT GAGGCTGGGG CTAGGTGGCA ATGCTCCAGT TTCCATCCCT 
CAACAGTCTC AGTCTGTCAA ACAGTTACTT CCAAGTGGAA ATGGGAGGTC CTACGGGCTA 
GGTGCTGAGC AGAGGCCCCC GGCAGCTGCC AGGTATTCCC TGCAGACTGC CAACACGTCC 
TCTCTACCCC CAGGCCAGGT AAAGTCTCCC TCTGTGTCTC AGTCACAGGC ATCTAGAGTA 
TTAGGTCAGT CCAGTTCTAA ACCTCCACCA GCAGCCACAG GCCCTCCTCC AAGCAACCAT 
TGTGCCACTC AGAAGTGGAA AATATGTACA ATCTGTAATG AGCTTTTTCC TGAGAATGTC 
TACAGTGTTC ACTTCGAAAA GGAACATAAA GCGGAGAAAG TTCCAGCAGT AGCTAACTAC 
ATTATGAAAA TACACAATTT TACTAGCAAA TGCCTCTATT GTAATCGCTA TCTGCCCACA 
GATACCCTGC TCAACCATAT GTTAATTCAT GGTCTGTCTT GTCCATATTG CCGTTCCACC 
TTCAATGATG TGGAGAAGAT GGCAGCACAC ATGCGAATGG TTCATATTGA TGAGGAGATG 
GGGCCTAAAA CGGATTCTAC CTTGAGCTTT GATTTGACAT TGCAACAGGG CAGTCACACC 
AACATTCATC TCCTGGTGAC CACATACAAC CTGAGAGATG CCCCGGCTGA ATCAGTTGCT 
TACCATGCCC AAAATAATGC CCCAGTTCCT CCAAAGCCAC AACCAAAAGT TCAGGAAAAA 
GCTGATGTCC CTGTTAAAAG TTCACCTCAA GCTGCAGTGC CCTATAAAAA AGATGTGGGG 
AAGACCCTCT GCCCTCTCTG CTTTTCAATC CTAAAAGGAC CCATATCTGA TGCACTTGCA 
CATCATTTAC GAGAAAGACA CCAAGTTATT CAGACAGTTC ATCCGGTTGA GAAAAAGCTA 
ACTTACAAAT GTATCCATTG CCTTGGTGTG TATACTAGCA ACATGACAGC CTCAACCATC 
ACTCTGCATC TAGTCCACTG CAGGGGTGTT GGAAAGACCC AGAATGGCCA GGACAAGACA 
AACGCACCTT CTCGGCTCAA TCAGTCTCCA GGCCTGGCCC CTGTGAAGCG CACATATGAG 
CAAATGGAGT TTCCACTGCT AAAGAAGCGA AAGCTGGAGG ATGAGAATGA CTCCCCAGGC 
TGCTTTGAAG AGAAGCCGGA AGAGCCTGTT GTTTTAGCTT TAGACCCCAA GGGTCATGAA 
GATGATTCAT ATGAAGCTAG GAAAAGCTTT CTCACAAAGT ACTTCAACAA ACAGCCCTAT 
CCCACTAGGA GAGAAATTGA GAAGTTAGCT GCCAGTCTGT GGCTGTGGAA GAGCGACATT 
GCCTCCCATT TCAGTAACAA GAGGAAGAAG TGTGTCCGTG ACTGTGAGAA GTATAAGCCT 
GGTGTGCTGC TAGGTTTTAA CATGAAAGAA TTAAATAAAG TCAAACATGA GATGGATTTT 
GATGCTGAGT GGCTATTTGA AAATCATGAC GAGAAAGCCT CAAGAGTCAA TGCTAGCAAG 
ACTGTTGACA AAAAGCTTAA CCTTGGGAAA GAAGATGACA GCTTCTCAGA TAGTTTTGAA 
CATTTGGAAG AAGAATCCAA TGGAAGCGGC GGCCCTTTTG ACCCTGTCTT TGAAGTTGAG 
CCTAAAATTC CCAGTGATAA TGCAGAGGAG CCTGTGCCGA AGGTAATTCC TGAAGGTGCT 
TTGGAGTCTG AGAAGCTAGA CCAAAAAGAG GAGGAGGATG GTTCAAAATA TGAAACCATC 
CATTTGACTG AGGAACGAGC CAAACTGATG CATGATGCCT CTGATAGTGA GGTAGACCAA 
GATGATGTGG TTGAGTGGAA AGATGGTGCT TCGCCATCTG AGAGTGGGCC TGGTTCCCGA 
CAGGTCTCAG ACTTTGAGGA TAATACATGT GAAATGAAAC CAGGAACCTG GTCTGATGAG 
TCTTCCCAGA GTGAAGACGC AAGGAGCAGT AAGCCGGCTG CCAAAAAAAA GGCTACAGTG 
CAAGATGACA CAGAGCAGTT GAAATGGAAG AATAGTTCCT ATGGAAAAGT TGAAGGGTTT 
TGGTCCAAGG ACCAGTCACA GTGGGAAAAT GCATCTGAGA ATGCAGAGCG CTTACCAAAC 
CCACAGATTG AGTGGCAGAA TAGCACAATT GACAGTGAGG ATGGGGAGCA GTTTGACAGC 
ATGACCGATG GAGTTGCCGA TCCCATGCAC GGCAGCTTAA CTGGAGTGAA GCTGAGCAGC 
CAGCAAGCCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Alterations in Activity-Dependent Neuroprotective Protein in Sporadic and Experimental Parkinson's Disease.
Journal of Parkinson's disease6(1)77-97(2016)
Chu Y,Morfini GA,Kordower JH

The NAP motif of activity-dependent neuroprotective protein (ADNP) regulates dendritic spines through microtubule end binding proteins.
Molecular psychiatry19(10)1115-24(2014 Oct)
Oz S,Kapitansky O,Ivashco-Pachima Y,Malishkevich A,Giladi E,Skalka N,Rosin-Arbesfeld R,Mittelman L,Segev O,Hirsch JA,Gozes I

Involvement of PACAP/ADNP signaling in the resistance to cell death in malignant peripheral nerve sheath tumor (MPNST) cells.
Journal of molecular neuroscience : MN48(3)674-83(2012 Nov)
Castorina A,Giunta S,Scuderi S,D'Agata V

The ADNP derived peptide, NAP modulates the tubulin pool: implication for neurotrophic and neuroprotective activities.
PloS one7(12)e51458(2012)
Oz S,Ivashko-Pachima Y,Gozes I

Nitric oxide regulates activity-dependent neuroprotective protein (ADNP) in the dentate gyrus of the rodent model of kainic acid-induced seizure.
Journal of molecular neuroscience : MN39(1-2)9-21(2009 Sep)
Cosgrave AS,McKay JS,Morris R,Quinn JP,Thippeswamy T

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Adnp cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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