Pttg1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Pttg1
Entrez Gene ID	64193
Full Name	pituitary tumor-transforming 1
Synonyms	Pttg
General protein information	Preferred Names pituitary tumor-transforming 1 Names securin Pituitary tumor transforming pituitary tumor-transforming gene 1 protein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q21

mRNA and Protein(s)

mRNA	Protein	Name
XM_006246142.1	XP_006246204.1	securin isoform X1
XM_006246144.1	XP_006246206.1	securin isoform X1
XM_006246145.3	XP_006246207.1	securin isoform X1
XM_006246143.3	XP_006246205.1	securin isoform X1
NM_022391.3	NP_071786.1	securin

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Pttg1	NP_001124526.1
Gallus gallus (chicken)	PTTG1	NP_001264669.1
Pan troglodytes (chimpanzee)	PTTG1	NP_001129088.2
Rattus norvegicus (Norway rat)	Pttg1	NP_071786.1
Homo sapiens (human)	PTTG1	NP_004210.1
	PTTG1	XP_001085022.1
Canis lupus familiaris (dog)	PTTG1	XP_536445.2
Bos taurus (cattle)	LOC100848911	XP_005209751.1
Xenopus tropicalis (tropical clawed frog)	LOC100498440	XP_004913545.1

Gene Ontology
Bibliography

Related articles in PubMed

Expression of EAP1 and CUX1 in the hypothalamus of female rats and relationship with KISS1 and GnRH.
Xu J, Li P
Endocrine journal63(8)681-90(2016 Aug)

Effects of silencing connexin43 on expression of pituitary tumor-transforming gene in prolactinomas.
Wang H, Zhang Y, Zhou A, Zhang R, Meng Q
Neurological research37(2)153-8(2015 Feb)

Expression levels of pituitary tumor transforming 1 and glutathione-S-transferase theta 3 are associated with the individual susceptibility to D-galactosamine-induced hepatotoxicity.
Yun JW, Kim CW, Bae IH, Park YH, Chung JH, Lim KM, Kang KS
Toxicology and applied pharmacology242(1)91-9(2010 Jan)

Loss of Cdc20 causes a securin-dependent metaphase arrest in two-cell mouse embryos.
Li M, York JP, Zhang P
Molecular and cellular biology27(9)3481-8(2007 May)

Separase: a universal trigger for sister chromatid disjunction but not chromosome cycle progression.
Wirth KG, Wutz G, Kudo NR, Desdouets C, Zetterberg A, Taghybeeglu S, Seznec J, Ducos GM, Ricci R, Firnberg N, Peters JM, Nasmyth K
The Journal of cell biology172(6)847-60(2006 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

EAP1 (Pttg1) gene may be involved in the neuroendocrine control of female puberty in correlation with the kisspeptin signaling.
Title: Expression of EAP1 and CUX1 in the hypothalamus of female rats and relationship with KISS1 and GnRH.

Altered Cx43 expression modulates Pituitary tumor transforming gene expression, which correlates with prolactinoma development.
Title: Effects of silencing connexin43 on expression of pituitary tumor-transforming gene in prolactinomas.

pttg1 could predict inter-individual susceptibility to D-galactosamine induced hepatotoxicity
Title: Expression levels of pituitary tumor transforming 1 and glutathione-S-transferase theta 3 are associated with the individual susceptibility to D-galactosamine-induced hepatotoxicity.

calcium sensing receptor stimulates the synthesis of PTTG mRNA in a nonmetastasizing model for humoral hypercalcemia of malignancy and, in the process, might induce angiogenesis via VEGF.
Title: Calcium-sensing receptor induces messenger ribonucleic acid of human securin, pituitary tumor transforming gene, in rat testicular cancer.

The following Pttg1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pttg1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa05727	NM_022391.3 Latest version!	Rattus norvegicus PTTG1 regulator of sister chromatid separation, securin (Pttg1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa05727	XM_006246145.3 Latest version!	Rattus norvegicus pituitary tumor-transforming 1 (Pttg1), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa05727	XM_006246142.1 Latest version!	Rattus norvegicus pituitary tumor-transforming 1 (Pttg1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa05727	XM_006246143.3 Latest version!	Rattus norvegicus pituitary tumor-transforming 1 (Pttg1), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa05727	XM_006246144.1 Latest version!	Rattus norvegicus pituitary tumor-transforming 1 (Pttg1), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Pttg1 ( NM_022391.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_071786.1 Rattus norvegicus PTTG1 regulator of sister chromatid separation, securin (Pttg1), mRNA.

Price & Availability↑

CloneID	ORa05727
Clone ID Related Accession (Same CDS sequence)	XM_006246142.1 , XM_006246144.1 , XM_006246145.3 , XM_006246143.3 , NM_022391.3
Accession Version	NM_022391.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 600bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-18
Organism	Rattus norvegicus(Norway rat)
Product	securin
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07029449.1. On or before Nov 30, 2016 this sequence version replaced XM_008767643.2, NM_022391.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BF550073.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906347 [ECO:0000348] ##Evidence-Data-END##

ATGGCTACTC TGATCTTTGT TGATAAGGAT AACGAAGAGC CAGGCAGCCG TTTGGCATCT 
AAGGATGGAT TGAAGCTGGG CTCTGGTGTC AAAGCCTTAG ATGGGAAATT GCAGGTTTCA 
ACGCCACGAG TCGGCAAAGT GTTCGGTGCC CCAGGCTTGC CTAAAGCCAG CAGGAAGGCT 
CTGGGAACTG TCAACAGAGT TACTGAAAAG CCAGTGAAGA GTAGTAAACC CCTGCAATCG 
AAACAGCCGA CTCTGAGTGT GAAAAAGATC ACCGAGAAGT CTACTAAGAC ACAAGGCTCT 
GCTCCTGCTC CTGATGATGC CTACCCAGAA ATAGAAAAGT TCTTCCCCTT CGATCCTCTA 
GATTTTGAGA GTTTTGACCT GCCTGAAGAG CACCAGATCT CACTTCTCCC CTTGAATGGA 
GTGCCTCTCA TGATCCTGAA TGAAGAGAGG GGGCTTGAGA AGCTGCTGCA CCTGGACCCC 
CCTTCCCCTC TGCAGAAGCC CTTCCTACCG TGGGAATCTG ATCCGTTGCC GTCTCCTCCC 
AGCGCCCTCT CCGCTCTGGA TGTTGAATTG CCGCCTGTTT GTTACGATGC AGATATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071786.1
CDS	37..636
Translation	MATLIFVDKDNEEPGSRLASKDGLKLGSGVKALDGKLQVSTPRVGKVFGAPGLPKASRKALGTVNRVTEKPVKSSKPLQSKQPTLSVKKITEKSTKTQGSAPAPDDAYPEIEKFFPFDPLDFESFDLPEEHQISLLPLNGVPLMILNEERGLEKLLHLDPPSPLQKPFLPWESDPLPSPPSALSALDVELPPVCYDADI

Target ORF information:

RefSeq Version	NM_022391.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus PTTG1 regulator of sister chromatid separation, securin (Pttg1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022391.3

ORF Insert Sequence:

ATGGCTACTC TGATCTTTGT TGATAAGGAT AACGAAGAGC CAGGCAGCCG TTTGGCATCT 
AAGGATGGAT TGAAGCTGGG CTCTGGTGTC AAAGCCTTAG ATGGGAAATT GCAGGTTTCA 
ACGCCACGAG TCGGCAAAGT GTTCGGTGCC CCAGGCTTGC CTAAAGCCAG CAGGAAGGCT 
CTGGGAACTG TCAACAGAGT TACTGAAAAG CCAGTGAAGA GTAGTAAACC CCTGCAATCG 
AAACAGCCGA CTCTGAGTGT GAAAAAGATC ACCGAGAAGT CTACTAAGAC ACAAGGCTCT 
GCTCCTGCTC CTGATGATGC CTACCCAGAA ATAGAAAAGT TCTTCCCCTT CGATCCTCTA 
GATTTTGAGA GTTTTGACCT GCCTGAAGAG CACCAGATCT CACTTCTCCC CTTGAATGGA 
GTGCCTCTCA TGATCCTGAA TGAAGAGAGG GGGCTTGAGA AGCTGCTGCA CCTGGACCCC 
CCTTCCCCTC TGCAGAAGCC CTTCCTACCG TGGGAATCTG ATCCGTTGCC GTCTCCTCCC 
AGCGCCCTCT CCGCTCTGGA TGTTGAATTG CCGCCTGTTT GTTACGATGC AGATATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pttg1 ( XM_006246142.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006246204.1 Rattus norvegicus pituitary tumor-transforming 1 (Pttg1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa05727
Clone ID Related Accession (Same CDS sequence)	XM_006246142.1 , XM_006246144.1 , XM_006246145.3 , XM_006246143.3 , NM_022391.3
Accession Version	XM_006246142.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 600bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	securin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTACTC TGATCTTTGT TGATAAGGAT AACGAAGAGC CAGGCAGCCG TTTGGCATCT 
AAGGATGGAT TGAAGCTGGG CTCTGGTGTC AAAGCCTTAG ATGGGAAATT GCAGGTTTCA 
ACGCCACGAG TCGGCAAAGT GTTCGGTGCC CCAGGCTTGC CTAAAGCCAG CAGGAAGGCT 
CTGGGAACTG TCAACAGAGT TACTGAAAAG CCAGTGAAGA GTAGTAAACC CCTGCAATCG 
AAACAGCCGA CTCTGAGTGT GAAAAAGATC ACCGAGAAGT CTACTAAGAC ACAAGGCTCT 
GCTCCTGCTC CTGATGATGC CTACCCAGAA ATAGAAAAGT TCTTCCCCTT CGATCCTCTA 
GATTTTGAGA GTTTTGACCT GCCTGAAGAG CACCAGATCT CACTTCTCCC CTTGAATGGA 
GTGCCTCTCA TGATCCTGAA TGAAGAGAGG GGGCTTGAGA AGCTGCTGCA CCTGGACCCC 
CCTTCCCCTC TGCAGAAGCC CTTCCTACCG TGGGAATCTG ATCCGTTGCC GTCTCCTCCC 
AGCGCCCTCT CCGCTCTGGA TGTTGAATTG CCGCCTGTTT GTTACGATGC AGATATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006246204.1
CDS	92..691
Translation	MATLIFVDKDNEEPGSRLASKDGLKLGSGVKALDGKLQVSTPRVGKVFGAPGLPKASRKALGTVNRVTEKPVKSSKPLQSKQPTLSVKKITEKSTKTQGSAPAPDDAYPEIEKFFPFDPLDFESFDLPEEHQISLLPLNGVPLMILNEERGLEKLLHLDPPSPLQKPFLPWESDPLPSPPSALSALDVELPPVCYDADI

Target ORF information:

RefSeq Version	XM_006246142.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus pituitary tumor-transforming 1 (Pttg1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006246142.1

ORF Insert Sequence:

ATGGCTACTC TGATCTTTGT TGATAAGGAT AACGAAGAGC CAGGCAGCCG TTTGGCATCT 
AAGGATGGAT TGAAGCTGGG CTCTGGTGTC AAAGCCTTAG ATGGGAAATT GCAGGTTTCA 
ACGCCACGAG TCGGCAAAGT GTTCGGTGCC CCAGGCTTGC CTAAAGCCAG CAGGAAGGCT 
CTGGGAACTG TCAACAGAGT TACTGAAAAG CCAGTGAAGA GTAGTAAACC CCTGCAATCG 
AAACAGCCGA CTCTGAGTGT GAAAAAGATC ACCGAGAAGT CTACTAAGAC ACAAGGCTCT 
GCTCCTGCTC CTGATGATGC CTACCCAGAA ATAGAAAAGT TCTTCCCCTT CGATCCTCTA 
GATTTTGAGA GTTTTGACCT GCCTGAAGAG CACCAGATCT CACTTCTCCC CTTGAATGGA 
GTGCCTCTCA TGATCCTGAA TGAAGAGAGG GGGCTTGAGA AGCTGCTGCA CCTGGACCCC 
CCTTCCCCTC TGCAGAAGCC CTTCCTACCG TGGGAATCTG ATCCGTTGCC GTCTCCTCCC 
AGCGCCCTCT CCGCTCTGGA TGTTGAATTG CCGCCTGTTT GTTACGATGC AGATATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pttg1 ( XM_006246144.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006246206.1 Rattus norvegicus pituitary tumor-transforming 1 (Pttg1), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa05727
Clone ID Related Accession (Same CDS sequence)	XM_006246142.1 , XM_006246144.1 , XM_006246145.3 , XM_006246143.3 , NM_022391.3
Accession Version	XM_006246144.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 600bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	securin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTACTC TGATCTTTGT TGATAAGGAT AACGAAGAGC CAGGCAGCCG TTTGGCATCT 
AAGGATGGAT TGAAGCTGGG CTCTGGTGTC AAAGCCTTAG ATGGGAAATT GCAGGTTTCA 
ACGCCACGAG TCGGCAAAGT GTTCGGTGCC CCAGGCTTGC CTAAAGCCAG CAGGAAGGCT 
CTGGGAACTG TCAACAGAGT TACTGAAAAG CCAGTGAAGA GTAGTAAACC CCTGCAATCG 
AAACAGCCGA CTCTGAGTGT GAAAAAGATC ACCGAGAAGT CTACTAAGAC ACAAGGCTCT 
GCTCCTGCTC CTGATGATGC CTACCCAGAA ATAGAAAAGT TCTTCCCCTT CGATCCTCTA 
GATTTTGAGA GTTTTGACCT GCCTGAAGAG CACCAGATCT CACTTCTCCC CTTGAATGGA 
GTGCCTCTCA TGATCCTGAA TGAAGAGAGG GGGCTTGAGA AGCTGCTGCA CCTGGACCCC 
CCTTCCCCTC TGCAGAAGCC CTTCCTACCG TGGGAATCTG ATCCGTTGCC GTCTCCTCCC 
AGCGCCCTCT CCGCTCTGGA TGTTGAATTG CCGCCTGTTT GTTACGATGC AGATATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006246206.1
CDS	386..985
Translation	MATLIFVDKDNEEPGSRLASKDGLKLGSGVKALDGKLQVSTPRVGKVFGAPGLPKASRKALGTVNRVTEKPVKSSKPLQSKQPTLSVKKITEKSTKTQGSAPAPDDAYPEIEKFFPFDPLDFESFDLPEEHQISLLPLNGVPLMILNEERGLEKLLHLDPPSPLQKPFLPWESDPLPSPPSALSALDVELPPVCYDADI

Target ORF information:

RefSeq Version	XM_006246144.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus pituitary tumor-transforming 1 (Pttg1), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006246144.1

ORF Insert Sequence:

ATGGCTACTC TGATCTTTGT TGATAAGGAT AACGAAGAGC CAGGCAGCCG TTTGGCATCT 
AAGGATGGAT TGAAGCTGGG CTCTGGTGTC AAAGCCTTAG ATGGGAAATT GCAGGTTTCA 
ACGCCACGAG TCGGCAAAGT GTTCGGTGCC CCAGGCTTGC CTAAAGCCAG CAGGAAGGCT 
CTGGGAACTG TCAACAGAGT TACTGAAAAG CCAGTGAAGA GTAGTAAACC CCTGCAATCG 
AAACAGCCGA CTCTGAGTGT GAAAAAGATC ACCGAGAAGT CTACTAAGAC ACAAGGCTCT 
GCTCCTGCTC CTGATGATGC CTACCCAGAA ATAGAAAAGT TCTTCCCCTT CGATCCTCTA 
GATTTTGAGA GTTTTGACCT GCCTGAAGAG CACCAGATCT CACTTCTCCC CTTGAATGGA 
GTGCCTCTCA TGATCCTGAA TGAAGAGAGG GGGCTTGAGA AGCTGCTGCA CCTGGACCCC 
CCTTCCCCTC TGCAGAAGCC CTTCCTACCG TGGGAATCTG ATCCGTTGCC GTCTCCTCCC 
AGCGCCCTCT CCGCTCTGGA TGTTGAATTG CCGCCTGTTT GTTACGATGC AGATATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pttg1 ( XM_006246145.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006246207.1 Rattus norvegicus pituitary tumor-transforming 1 (Pttg1), transcript variant X5, mRNA.

Price & Availability↑

CloneID	ORa05727
Clone ID Related Accession (Same CDS sequence)	XM_006246142.1 , XM_006246144.1 , XM_006246145.3 , XM_006246143.3 , NM_022391.3
Accession Version	XM_006246145.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 600bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	securin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006246145.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTACTC TGATCTTTGT TGATAAGGAT AACGAAGAGC CAGGCAGCCG TTTGGCATCT 
AAGGATGGAT TGAAGCTGGG CTCTGGTGTC AAAGCCTTAG ATGGGAAATT GCAGGTTTCA 
ACGCCACGAG TCGGCAAAGT GTTCGGTGCC CCAGGCTTGC CTAAAGCCAG CAGGAAGGCT 
CTGGGAACTG TCAACAGAGT TACTGAAAAG CCAGTGAAGA GTAGTAAACC CCTGCAATCG 
AAACAGCCGA CTCTGAGTGT GAAAAAGATC ACCGAGAAGT CTACTAAGAC ACAAGGCTCT 
GCTCCTGCTC CTGATGATGC CTACCCAGAA ATAGAAAAGT TCTTCCCCTT CGATCCTCTA 
GATTTTGAGA GTTTTGACCT GCCTGAAGAG CACCAGATCT CACTTCTCCC CTTGAATGGA 
GTGCCTCTCA TGATCCTGAA TGAAGAGAGG GGGCTTGAGA AGCTGCTGCA CCTGGACCCC 
CCTTCCCCTC TGCAGAAGCC CTTCCTACCG TGGGAATCTG ATCCGTTGCC GTCTCCTCCC 
AGCGCCCTCT CCGCTCTGGA TGTTGAATTG CCGCCTGTTT GTTACGATGC AGATATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006246207.1
CDS	92..691
Translation	MATLIFVDKDNEEPGSRLASKDGLKLGSGVKALDGKLQVSTPRVGKVFGAPGLPKASRKALGTVNRVTEKPVKSSKPLQSKQPTLSVKKITEKSTKTQGSAPAPDDAYPEIEKFFPFDPLDFESFDLPEEHQISLLPLNGVPLMILNEERGLEKLLHLDPPSPLQKPFLPWESDPLPSPPSALSALDVELPPVCYDADI

Target ORF information:

RefSeq Version	XM_006246145.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus pituitary tumor-transforming 1 (Pttg1), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006246145.3

ORF Insert Sequence:

ATGGCTACTC TGATCTTTGT TGATAAGGAT AACGAAGAGC CAGGCAGCCG TTTGGCATCT 
AAGGATGGAT TGAAGCTGGG CTCTGGTGTC AAAGCCTTAG ATGGGAAATT GCAGGTTTCA 
ACGCCACGAG TCGGCAAAGT GTTCGGTGCC CCAGGCTTGC CTAAAGCCAG CAGGAAGGCT 
CTGGGAACTG TCAACAGAGT TACTGAAAAG CCAGTGAAGA GTAGTAAACC CCTGCAATCG 
AAACAGCCGA CTCTGAGTGT GAAAAAGATC ACCGAGAAGT CTACTAAGAC ACAAGGCTCT 
GCTCCTGCTC CTGATGATGC CTACCCAGAA ATAGAAAAGT TCTTCCCCTT CGATCCTCTA 
GATTTTGAGA GTTTTGACCT GCCTGAAGAG CACCAGATCT CACTTCTCCC CTTGAATGGA 
GTGCCTCTCA TGATCCTGAA TGAAGAGAGG GGGCTTGAGA AGCTGCTGCA CCTGGACCCC 
CCTTCCCCTC TGCAGAAGCC CTTCCTACCG TGGGAATCTG ATCCGTTGCC GTCTCCTCCC 
AGCGCCCTCT CCGCTCTGGA TGTTGAATTG CCGCCTGTTT GTTACGATGC AGATATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pttg1 ( XM_006246143.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006246205.1 Rattus norvegicus pituitary tumor-transforming 1 (Pttg1), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa05727
Clone ID Related Accession (Same CDS sequence)	XM_006246142.1 , XM_006246144.1 , XM_006246145.3 , XM_006246143.3 , NM_022391.3
Accession Version	XM_006246143.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 600bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	securin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006246143.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTACTC TGATCTTTGT TGATAAGGAT AACGAAGAGC CAGGCAGCCG TTTGGCATCT 
AAGGATGGAT TGAAGCTGGG CTCTGGTGTC AAAGCCTTAG ATGGGAAATT GCAGGTTTCA 
ACGCCACGAG TCGGCAAAGT GTTCGGTGCC CCAGGCTTGC CTAAAGCCAG CAGGAAGGCT 
CTGGGAACTG TCAACAGAGT TACTGAAAAG CCAGTGAAGA GTAGTAAACC CCTGCAATCG 
AAACAGCCGA CTCTGAGTGT GAAAAAGATC ACCGAGAAGT CTACTAAGAC ACAAGGCTCT 
GCTCCTGCTC CTGATGATGC CTACCCAGAA ATAGAAAAGT TCTTCCCCTT CGATCCTCTA 
GATTTTGAGA GTTTTGACCT GCCTGAAGAG CACCAGATCT CACTTCTCCC CTTGAATGGA 
GTGCCTCTCA TGATCCTGAA TGAAGAGAGG GGGCTTGAGA AGCTGCTGCA CCTGGACCCC 
CCTTCCCCTC TGCAGAAGCC CTTCCTACCG TGGGAATCTG ATCCGTTGCC GTCTCCTCCC 
AGCGCCCTCT CCGCTCTGGA TGTTGAATTG CCGCCTGTTT GTTACGATGC AGATATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006246205.1
CDS	292..891
Translation	MATLIFVDKDNEEPGSRLASKDGLKLGSGVKALDGKLQVSTPRVGKVFGAPGLPKASRKALGTVNRVTEKPVKSSKPLQSKQPTLSVKKITEKSTKTQGSAPAPDDAYPEIEKFFPFDPLDFESFDLPEEHQISLLPLNGVPLMILNEERGLEKLLHLDPPSPLQKPFLPWESDPLPSPPSALSALDVELPPVCYDADI

Target ORF information:

RefSeq Version	XM_006246143.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus pituitary tumor-transforming 1 (Pttg1), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006246143.3

ORF Insert Sequence:

ATGGCTACTC TGATCTTTGT TGATAAGGAT AACGAAGAGC CAGGCAGCCG TTTGGCATCT 
AAGGATGGAT TGAAGCTGGG CTCTGGTGTC AAAGCCTTAG ATGGGAAATT GCAGGTTTCA 
ACGCCACGAG TCGGCAAAGT GTTCGGTGCC CCAGGCTTGC CTAAAGCCAG CAGGAAGGCT 
CTGGGAACTG TCAACAGAGT TACTGAAAAG CCAGTGAAGA GTAGTAAACC CCTGCAATCG 
AAACAGCCGA CTCTGAGTGT GAAAAAGATC ACCGAGAAGT CTACTAAGAC ACAAGGCTCT 
GCTCCTGCTC CTGATGATGC CTACCCAGAA ATAGAAAAGT TCTTCCCCTT CGATCCTCTA 
GATTTTGAGA GTTTTGACCT GCCTGAAGAG CACCAGATCT CACTTCTCCC CTTGAATGGA 
GTGCCTCTCA TGATCCTGAA TGAAGAGAGG GGGCTTGAGA AGCTGCTGCA CCTGGACCCC 
CCTTCCCCTC TGCAGAAGCC CTTCCTACCG TGGGAATCTG ATCCGTTGCC GTCTCCTCCC 
AGCGCCCTCT CCGCTCTGGA TGTTGAATTG CCGCCTGTTT GTTACGATGC AGATATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Expression of EAP1 and CUX1 in the hypothalamus of female rats and relationship with KISS1 and GnRH.
Endocrine journal63(8)681-90(2016 Aug)
Xu J,Li P

Effects of silencing connexin43 on expression of pituitary tumor-transforming gene in prolactinomas.
Neurological research37(2)153-8(2015 Feb)
Wang H,Zhang Y,Zhou A,Zhang R,Meng Q

Expression levels of pituitary tumor transforming 1 and glutathione-S-transferase theta 3 are associated with the individual susceptibility to D-galactosamine-induced hepatotoxicity.
Toxicology and applied pharmacology242(1)91-9(2010 Jan)
Yun JW,Kim CW,Bae IH,Park YH,Chung JH,Lim KM,Kang KS

Loss of Cdc20 causes a securin-dependent metaphase arrest in two-cell mouse embryos.
Molecular and cellular biology27(9)3481-8(2007 May)
Li M,York JP,Zhang P

Separase: a universal trigger for sister chromatid disjunction but not chromosome cycle progression.
The Journal of cell biology172(6)847-60(2006 Mar)
Wirth KG,Wutz G,Kudo NR,Desdouets C,Zetterberg A,Taghybeeglu S,Seznec J,Ducos GM,Ricci R,Firnberg N,Peters JM,Nasmyth K

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Pttg1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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