Defb25 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Defb25
Entrez Gene ID	641644
Full Name	defensin beta 25
General protein information	Preferred Names defensin beta 25 Names beta-defensin 25 BD-25
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3q41

mRNA and Protein(s)

mRNA	Protein	Name
NM_001037516.1	NP_001032605.1	beta-defensin 25 precursor

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Defb25	NP_001034211.1
Rattus norvegicus (Norway rat)	Defb25	NP_001032605.1

Gene Ontology
Bibliography

Related articles in PubMed

Beta-Defensin 124 Is Required for Efficient Innate Immune Responses in Prostate Epithelial RWPE-1 Cells.
Kim KH, Lee J, Han JH, Myung SC
Korean journal of urology55(6)417-25(2014 Jun)

Cross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract.
Patil AA, Cai Y, Sang Y, Blecha F, Zhang G
Physiological genomics23(1)5-17(2005 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Defb25 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Defb25 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa09391	NM_001037516.1 Latest version!	Rattus norvegicus defensin beta 25 (Defb25), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Defb25 ( NM_001037516.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001032605.1 Rattus norvegicus defensin beta 25 (Defb25), mRNA.

Price & Availability↑

CloneID	ORa09391
Clone ID Related Accession (Same CDS sequence)	NM_001037516.1
Accession Version	NM_001037516.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 216bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Rattus norvegicus(Norway rat)
Product	beta-defensin 25 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY621356.1. ##Evidence-Data-START## Transcript exon combination :: AY621356.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689601, SAMN02642602 [ECO:0000348] ##Evidence-Data-END##

ATGGCAAAGT GGATTCTGCT CATTGTGGCT CTCCTGGTCT TGGGTCATGT GCCATCAGGG 
AGCACTGAAT TCAAACGGTG CTGGAATGGC CAGGGGGCCT GCCGGACTTA CTGCACAAGG 
CAAGAGAAAT TCATCCACCT GTGTCCGGAT GCTTCTCTGT GCTGCCTGTC CTATTCTCTC 
AAGGCTTCAC CCCACTCAAG GGCTGGAGGT GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001032605.1
CDS	1..216
Translation	MAKWILLIVALLVLGHVPSGSTEFKRCWNGQGACRTYCTRQEKFIHLCPDASLCCLSYSLKASPHSRAGGV

Target ORF information:

RefSeq Version	NM_001037516.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus defensin beta 25 (Defb25), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001037516.1

ORF Insert Sequence:

ATGGCAAAGT GGATTCTGCT CATTGTGGCT CTCCTGGTCT TGGGTCATGT GCCATCAGGG 
AGCACTGAAT TCAAACGGTG CTGGAATGGC CAGGGGGCCT GCCGGACTTA CTGCACAAGG 
CAAGAGAAAT TCATCCACCT GTGTCCGGAT GCTTCTCTGT GCTGCCTGTC CTATTCTCTC 
AAGGCTTCAC CCCACTCAAG GGCTGGAGGT GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Beta-Defensin 124 Is Required for Efficient Innate Immune Responses in Prostate Epithelial RWPE-1 Cells.
Korean journal of urology55(6)417-25(2014 Jun)
Kim KH,Lee J,Han JH,Myung SC

Cross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract.
Physiological genomics23(1)5-17(2005 Sep)
Patil AA,Cai Y,Sang Y,Blecha F,Zhang G