Adgrl4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Adgrl4
Entrez Gene ID	64124
Full Name	adhesion G protein-coupled receptor L4
Synonyms	Eltd1,Etl
General protein information	Preferred Names adhesion G protein-coupled receptor L4 Names adhesion G protein-coupled receptor L4 EGF, latrophilin and seven transmembrane domain containing 1 EGF, latrophilin and seven transmembrane domain-containing protein 1 EGF, latrophilin seven transmembrane domain containing 1 EGF-TM7-latrophilin-related protein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q45
Summary	may play a role in heart development [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_022294.1	NP_071630.1	adhesion G protein-coupled receptor L4 precursor

Pathways from BioSystems

Homologies

	ELTD1	XP_001100419.1
Gallus gallus (chicken)	ELTD1	XP_004936723.1
Mus musculus (house mouse)	Eltd1	NP_573485.2
Homo sapiens (human)	ELTD1	NP_071442.2
Canis lupus familiaris (dog)	ELTD1	XP_005622081.1
Pan troglodytes (chimpanzee)	ELTD1	XP_001155188.2
Bos taurus (cattle)	ELTD1	NP_001070376.1
Rattus norvegicus (Norway rat)	Eltd1	NP_071630.1
Danio rerio (zebrafish)	eltd1	NP_998532.2
Xenopus tropicalis (tropical clawed frog)	LOC101731473	XP_004913969.1

Gene Ontology
Bibliography

Related articles in PubMed

ELTD1, an effective anti-angiogenic target for gliomas: preclinical assessment in mouse GL261 and human G55 xenograft glioma models.
Ziegler J, Pody R, Coutinho de Souza P, Evans B, Saunders D, Smith N, Mallory S, Njoku C, Dong Y, Chen H, Dong J, Lerner M, Mian O, Tummala S, Battiste J, Fung KM, Wren JD, Towner RA
Neuro-oncology19(2)175-185(2017 02)

ELTD1, a potential new biomarker for gliomas.
Towner RA, Jensen RL, Colman H, Vaillant B, Smith N, Casteel R, Saunders D, Gillespie DL, Silasi-Mansat R, Lupu F, Giles CB, Wren JD
Neurosurgery72(1)77-90; discussion 91(2013 Jan)

Augmented cardiac hypertrophy in response to pressure overload in mice lacking ELTD1.
Xiao J, Jiang H, Zhang R, Fan G, Zhang Y, Jiang D, Li H
PloS one7(5)e35779(2012)

ETL, a novel seven-transmembrane receptor that is developmentally regulated in the heart. ETL is a member of the secretin family and belongs to the epidermal growth factor-seven-transmembrane subfamily.
Nechiporuk T, Urness LD, Keating MT
The Journal of biological chemistry276(6)4150-7(2001 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Adgrl4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Adgrl4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa05653	NM_022294.1 Latest version!	Rattus norvegicus adhesion G protein-coupled receptor L4 (Adgrl4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	10-12	$433.30 $619.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Adgrl4 ( NM_022294.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_071630.1 Rattus norvegicus adhesion G protein-coupled receptor L4 (Adgrl4), mRNA.

Price & Availability↑

CloneID	ORa05653
Clone ID Related Accession (Same CDS sequence)	NM_022294.1
Accession Version	NM_022294.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2217bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-15
Organism	Rattus norvegicus(Norway rat)
Product	adhesion G protein-coupled receptor L4 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF192401.1. ##Evidence-Data-START## Transcript exon combination :: AF192401.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGAGACTCC TCCTGCTTCT AGTGGGTCTC TCCACTTTGC TGAATCACTC CTACACACAA 
AACTGCAAGA CACCGTGTCT CCCAAATGCC AAGTGTGAGG TGTTGGACGA AGTGGCAGCC 
TGCTTCTGCA GTACAGGCTA CACTGGGAAT GGCATCACGA TTTGTGAAGA TGTAGACGAG 
TGCAACGAGA CCTCCGTCTG CGGTGATCAC GCTGTGTGTG AAAACACGAA TGGAGGATTT 
AGCTGCTTCT GCGTGGAAGG TTATCAGACC TCCACCGGGA AGACGCAGTT CACGCCTAAT 
GATGGCTCTT ACTGCCAAGA TGTAGACGAG TGCAACGAGA CCTCCGTCTG CGGTGATCAC 
GCTGTGTGTG AAAACACGAA CGGAGGATTT AGCTGCTTCT GCGTGGAAGG TTATCAGACC 
TCCACCGGGA AGACGCAGTT CACGCCTAAT GATGGCTCTT ACTGCCAAGA AATTGTGAAT 
TCAAATTGCC ACTTAGAGCA TGACTGCATT GCTGCAAACA TTAATAAAAC TCTAAAAAGA 
ATTGGACCCA TAACAGAACA GCTGACTTTA CTCCATGAAA TCTACAAGAA TTCTGAGGCT 
GAGCTTTCTC TGGTGGATAT AGTCACATAC ATAGAGATAC TAACAGAATC ATCCTCACTA 
CAAGGCTACA TAAAGAACAC CACTTCGCCC AAGGATGCCT ACTTCGGTTC AGCTCTTACT 
GAATTTGGAA AAACCGTCAA TAATTTTGTT GAAAAGAACA CACATGAAAT GTGGGACCAG 
TTACCTACAA ATCGTAGAAG ACTCCATCTC ACAAAACTGA TGCACGCTGC TGAGCACGTC 
ACCTTACAGA TCTCTCAGAA CATCCAGAAG AATACTCAGT TTGACATGAA TTCTACCGAC 
TTGGCTCTCA AGGTTTTCGT TTTTGATTCA GTTCACATGA AGCATACTCA TCCCCATATG 
AATGTGGACG GAGGCTATGT AAAAATATCC CCGAGGAGAA AATCTGCATA TGACCCAAAT 
GGCAACGTCA TTGTTGCATT CCTGTGCTAT AGGAGCATTG GCCCCTTGCT TTCCTCATCT 
GACGACTTCT TACTGGGCGC TCAGAGTGAC AATTCCAAAG GAAAGGAGAA GGTCATTTCT 
TCAGTGATTT CTGCCTCAAT TAGCTCAAAC CCACCCACAC TGTATGAACT TGAAAAAATT 
ACATTTACAC TGAGTCATGT AAAGCTCTCA GATAAGCACC AGACACAGTG CGCCTTTTGG 
AACTACTCAG TCGATGACAT GAACAATGGC AGCTGGTCAT CTGAGGGCTG TGAGCTGACA 
TACTCCAACG ACACCCATAC TTCCTGCCGA TGTAGTCATC TGACACACTT TGCGATTTTG 
ATGTCCCCCA GTACCTCCAT TGAAGTTAAA GATTACAATA TCCTGACGAG GATCACTCAG 
CTGGGAATAA TCATCTCCCT GATCTGCCTC GCCATATGCA TTTTCACCTT CTGGTTCTTC 
AGTGAGATTC AAAGCACCAG GACCACAATC CACAAGAATC TCTGCTGCAG CCTCTTTCTT 
GCACAACTAG TTTTTCTTGT CGGCATCAAC ATAAACACAA ACAAGCTGGT CTGCTCTATC 
ATCGCTGGCC TGCTCCATTA CTTCTTCTTA GCTGCCTTTG CCTGGATGTG CATTGAAGGC 
ATCTACCTAT ACCTCATCGT TGTTGGGCTC ATCTATAACA AGGGGTTTTT ACACAAGAAC 
TTCTATATCT TTGGCTATCT TAGCCCGGCT GTAGTTGTTG GATTCTCGGC CTCTTTGGGA 
TACAGATATT ATGGTACCAC CAAAGTATGT TGGTTGAGCA CTGAAAACAA CTTTATCTGG 
AGCTTCATAG GGCCAGCGTG TCTAATCATT CTTGTTAATC TCTTGGCTTT TGGAGTTATC 
ATATACAAAG TGTTCCGCCA CACTGCTGGA CTGAAGCCAG AAGTTAGTTG CTACGAGAAC 
ATAAGGTCTT GCGCCAGAGG AGCCCTGGCC CTCCTCTTCC TTCTGGGTAC CACCTGGACC 
TTTGGGGTTC TCCACGTAGT GCATGCATCT GTTGTGACAG CCTACCTCTT CACAGTCAGC 
AACGCTTTCC AAGGGATGTT TATTTTCTTA TTCCTATGTG TTTTATCTAG AAAGATTCAA 
GAAGAATATT ACAGATTGTT CAAAAATGTC CCCTGCTGTT TTGAATGTTT AAGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071630.1
CDS	236..2452
Translation	MRLLLLLVGLSTLLNHSYTQNCKTPCLPNAKCEVLDEVAACFCSTGYTGNGITICEDVDECNETSVCGDHAVCENTNGGFSCFCVEGYQTSTGKTQFTPNDGSYCQDVDECNETSVCGDHAVCENTNGGFSCFCVEGYQTSTGKTQFTPNDGSYCQEIVNSNCHLEHDCIAANINKTLKRIGPITEQLTLLHEIYKNSEAELSLVDIVTYIEILTESSSLQGYIKNTTSPKDAYFGSALTEFGKTVNNFVEKNTHEMWDQLPTNRRRLHLTKLMHAAEHVTLQISQNIQKNTQFDMNSTDLALKVFVFDSVHMKHTHPHMNVDGGYVKISPRRKSAYDPNGNVIVAFLCYRSIGPLLSSSDDFLLGAQSDNSKGKEKVISSVISASISSNPPTLYELEKITFTLSHVKLSDKHQTQCAFWNYSVDDMNNGSWSSEGCELTYSNDTHTSCRCSHLTHFAILMSPSTSIEVKDYNILTRITQLGIIISLICLAICIFTFWFFSEIQSTRTTIHKNLCCSLFLAQLVFLVGININTNKLVCSIIAGLLHYFFLAAFAWMCIEGIYLYLIVVGLIYNKGFLHKNFYIFGYLSPAVVVGFSASLGYRYYGTTKVCWLSTENNFIWSFIGPACLIILVNLLAFGVIIYKVFRHTAGLKPEVSCYENIRSCARGALALLFLLGTTWTFGVLHVVHASVVTAYLFTVSNAFQGMFIFLFLCVLSRKIQEEYYRLFKNVPCCFECLR

Target ORF information:

RefSeq Version	NM_022294.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus adhesion G protein-coupled receptor L4 (Adgrl4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022294.1

ORF Insert Sequence:

ATGAGACTCC TCCTGCTTCT AGTGGGTCTC TCCACTTTGC TGAATCACTC CTACACACAA 
AACTGCAAGA CACCGTGTCT CCCAAATGCC AAGTGTGAGG TGTTGGACGA AGTGGCAGCC 
TGCTTCTGCA GTACAGGCTA CACTGGGAAT GGCATCACGA TTTGTGAAGA TGTAGACGAG 
TGCAACGAGA CCTCCGTCTG CGGTGATCAC GCTGTGTGTG AAAACACGAA TGGAGGATTT 
AGCTGCTTCT GCGTGGAAGG TTATCAGACC TCCACCGGGA AGACGCAGTT CACGCCTAAT 
GATGGCTCTT ACTGCCAAGA TGTAGACGAG TGCAACGAGA CCTCCGTCTG CGGTGATCAC 
GCTGTGTGTG AAAACACGAA CGGAGGATTT AGCTGCTTCT GCGTGGAAGG TTATCAGACC 
TCCACCGGGA AGACGCAGTT CACGCCTAAT GATGGCTCTT ACTGCCAAGA AATTGTGAAT 
TCAAATTGCC ACTTAGAGCA TGACTGCATT GCTGCAAACA TTAATAAAAC TCTAAAAAGA 
ATTGGACCCA TAACAGAACA GCTGACTTTA CTCCATGAAA TCTACAAGAA TTCTGAGGCT 
GAGCTTTCTC TGGTGGATAT AGTCACATAC ATAGAGATAC TAACAGAATC ATCCTCACTA 
CAAGGCTACA TAAAGAACAC CACTTCGCCC AAGGATGCCT ACTTCGGTTC AGCTCTTACT 
GAATTTGGAA AAACCGTCAA TAATTTTGTT GAAAAGAACA CACATGAAAT GTGGGACCAG 
TTACCTACAA ATCGTAGAAG ACTCCATCTC ACAAAACTGA TGCACGCTGC TGAGCACGTC 
ACCTTACAGA TCTCTCAGAA CATCCAGAAG AATACTCAGT TTGACATGAA TTCTACCGAC 
TTGGCTCTCA AGGTTTTCGT TTTTGATTCA GTTCACATGA AGCATACTCA TCCCCATATG 
AATGTGGACG GAGGCTATGT AAAAATATCC CCGAGGAGAA AATCTGCATA TGACCCAAAT 
GGCAACGTCA TTGTTGCATT CCTGTGCTAT AGGAGCATTG GCCCCTTGCT TTCCTCATCT 
GACGACTTCT TACTGGGCGC TCAGAGTGAC AATTCCAAAG GAAAGGAGAA GGTCATTTCT 
TCAGTGATTT CTGCCTCAAT TAGCTCAAAC CCACCCACAC TGTATGAACT TGAAAAAATT 
ACATTTACAC TGAGTCATGT AAAGCTCTCA GATAAGCACC AGACACAGTG CGCCTTTTGG 
AACTACTCAG TCGATGACAT GAACAATGGC AGCTGGTCAT CTGAGGGCTG TGAGCTGACA 
TACTCCAACG ACACCCATAC TTCCTGCCGA TGTAGTCATC TGACACACTT TGCGATTTTG 
ATGTCCCCCA GTACCTCCAT TGAAGTTAAA GATTACAATA TCCTGACGAG GATCACTCAG 
CTGGGAATAA TCATCTCCCT GATCTGCCTC GCCATATGCA TTTTCACCTT CTGGTTCTTC 
AGTGAGATTC AAAGCACCAG GACCACAATC CACAAGAATC TCTGCTGCAG CCTCTTTCTT 
GCACAACTAG TTTTTCTTGT CGGCATCAAC ATAAACACAA ACAAGCTGGT CTGCTCTATC 
ATCGCTGGCC TGCTCCATTA CTTCTTCTTA GCTGCCTTTG CCTGGATGTG CATTGAAGGC 
ATCTACCTAT ACCTCATCGT TGTTGGGCTC ATCTATAACA AGGGGTTTTT ACACAAGAAC 
TTCTATATCT TTGGCTATCT TAGCCCGGCT GTAGTTGTTG GATTCTCGGC CTCTTTGGGA 
TACAGATATT ATGGTACCAC CAAAGTATGT TGGTTGAGCA CTGAAAACAA CTTTATCTGG 
AGCTTCATAG GGCCAGCGTG TCTAATCATT CTTGTTAATC TCTTGGCTTT TGGAGTTATC 
ATATACAAAG TGTTCCGCCA CACTGCTGGA CTGAAGCCAG AAGTTAGTTG CTACGAGAAC 
ATAAGGTCTT GCGCCAGAGG AGCCCTGGCC CTCCTCTTCC TTCTGGGTAC CACCTGGACC 
TTTGGGGTTC TCCACGTAGT GCATGCATCT GTTGTGACAG CCTACCTCTT CACAGTCAGC 
AACGCTTTCC AAGGGATGTT TATTTTCTTA TTCCTATGTG TTTTATCTAG AAAGATTCAA 
GAAGAATATT ACAGATTGTT CAAAAATGTC CCCTGCTGTT TTGAATGTTT AAGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

ELTD1, an effective anti-angiogenic target for gliomas: preclinical assessment in mouse GL261 and human G55 xenograft glioma models.
Neuro-oncology19(2)175-185(2017 02)
Ziegler J,Pody R,Coutinho de Souza P,Evans B,Saunders D,Smith N,Mallory S,Njoku C,Dong Y,Chen H,Dong J,Lerner M,Mian O,Tummala S,Battiste J,Fung KM,Wren JD,Towner RA

ELTD1, a potential new biomarker for gliomas.
Neurosurgery72(1)77-90; discussion 91(2013 Jan)
Towner RA,Jensen RL,Colman H,Vaillant B,Smith N,Casteel R,Saunders D,Gillespie DL,Silasi-Mansat R,Lupu F,Giles CB,Wren JD

Augmented cardiac hypertrophy in response to pressure overload in mice lacking ELTD1.
PloS one7(5)e35779(2012)
Xiao J,Jiang H,Zhang R,Fan G,Zhang Y,Jiang D,Li H

ETL, a novel seven-transmembrane receptor that is developmentally regulated in the heart. ETL is a member of the secretin family and belongs to the epidermal growth factor-seven-transmembrane subfamily.
The Journal of biological chemistry276(6)4150-7(2001 Feb)
Nechiporuk T,Urness LD,Keating MT

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Adgrl4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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