Cxcl6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cxcl6
Entrez Gene ID	60665
Full Name	C-X-C motif chemokine ligand 6
Synonyms	Cxcl5
General protein information	Preferred Names C-X-C motif chemokine ligand 6 Names C-X-C motif chemokine 5 CXC chemokine LIX chemokine (C-X-C motif) ligand 5 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) cytokine LIX small-inducible cytokine B5
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 14 Map Location: 14p22
Summary	mouse homolog is a member of the CXC chemokine family, is a neutrophil chemoattractant and is rapidly induced in response to muscle injury [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_017599366.1	XP_017454855.1	C-X-C motif chemokine 5 isoform X1
XM_017599367.1	XP_017454856.1	C-X-C motif chemokine 5 isoform X1
NM_022214.1	NP_071550.1	C-X-C motif chemokine 5 precursor
XM_008770054.1	XP_008768276.1	C-X-C motif chemokine 5 isoform X1
XM_017599368.1	XP_017454857.1	C-X-C motif chemokine 5 isoform X2

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Cxcl5	NP_033167.2
Rattus norvegicus (Norway rat)	Cxcl5	NP_071550.1
Pan troglodytes (chimpanzee)	CXCL6	XP_001156255.1
	CXCL6	XP_001103136.1
Homo sapiens (human)	CXCL6	NP_002984.1

Gene Ontology
Bibliography

Related articles in PubMed

Corticotropin-Releasing Hormone Suppresses Synapse Formation in the Hippocampus of Male Rats via Inhibition of CXCL5 Secretion by Glia.
Zhang Y, Zheng Y, Xu Y, Sheng H, Ni X
Endocrinology159(2)622-638(2018 Feb)

Spinal CXCL5 contributes to nerve injury-induced neuropathic pain via modulating GSK-3? phosphorylation and activity in rats.
Xu W, Zhu M, Yuan S, Yu W
Neuroscience letters63452-59(2016 Nov)

JCV agnoprotein-induced reduction in CXCL5/LIX secretion by oligodendrocytes is associated with activation of apoptotic signaling in neurons.
Merabova N, Kaminski R, Krynska B, Amini S, Khalili K, Darbinyan A
Journal of cellular physiology227(8)3119-27(2012 Aug)

CXCL5 mediates UVB irradiation-induced pain.
Dawes JM, Calvo M, Perkins JR, Paterson KJ, Kiesewetter H, Hobbs C, Kaan TK, Orengo C, Bennett DL, McMahon SB
Science translational medicine3(90)90ra60(2011 Jul)

Adipose tissue-derived stem cells secrete CXCL5 cytokine with neurotrophic effects on cavernous nerve regeneration.
Zhang H, Yang R, Wang Z, Lin G, Lue TF, Lin CS
The journal of sexual medicine8(2)437-46(2011 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

up-regulation of spinal CXCL5 and CXCR2 is involved in neuropathic pain after nerve injury, through regulating GSK-3beta activity in rats.
Title: Spinal CXCL5 contributes to nerve injury-induced neuropathic pain via modulating GSK-3? phosphorylation and activity in rats.

Analysis of mitogen-activated protein kinases (MAPK) and glycogen synthase kinase (GSK3) pathways showed that they are involved in mechanisms of neuronal apoptosis in response to the depletion of CXCL5/LIX signaling.
Title: JCV agnoprotein-induced reduction in CXCL5/LIX secretion by oligodendrocytes is associated with activation of apoptotic signaling in neurons.

Data demonstrate that the chemokine CXCL5 is a peripheral mediator of UVB-induced inflammatory pain, likely in humans as well as rats.
Title: CXCL5 mediates UVB irradiation-induced pain.

Disrupted expression of CXCL5 in colorectal cancer is associated with rapid tumor formation in rats and poor prognosis in patients.
Title: Disrupted expression of CXCL5 in colorectal cancer is associated with rapid tumor formation in rats and poor prognosis in patients.

The following Cxcl6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cxcl6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa13693	NM_022214.1 Latest version!	Rattus norvegicus C-X-C motif chemokine ligand 6 (Cxcl6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa43536	XM_017599366.1 Latest version!	Rattus norvegicus C-X-C motif chemokine ligand 6 (Cxcl6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa43536	XM_008770054.1 Latest version!	Rattus norvegicus C-X-C motif chemokine ligand 6 (Cxcl6), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa43536	XM_017599367.1 Latest version!	Rattus norvegicus C-X-C motif chemokine ligand 6 (Cxcl6), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa43537	XM_017599368.1 Latest version!	Rattus norvegicus C-X-C motif chemokine ligand 6 (Cxcl6), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cxcl6 ( NM_022214.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_071550.1 Rattus norvegicus C-X-C motif chemokine ligand 6 (Cxcl6), mRNA.

Price & Availability↑

CloneID	ORa13693
Clone ID Related Accession (Same CDS sequence)	NM_022214.1
Accession Version	NM_022214.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 393bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Rattus norvegicus(Norway rat)
Product	C-X-C motif chemokine 5 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U90448.1. On or before Jun 25, 2006 this sequence version replaced XM_001068757.1, XM_001072333.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U90448.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689599, SAMEA2689603 [ECO:0000348] ##Evidence-Data-END##

ATGAGCTTCC AGCTCCGCAG CTCCGCCCGC ATCCCTAGCC GGTCCTGCTC GTCATTCACC 
CTGCTGGCAT TTCTGCTGCT GTTCACACTG CCACAGCATC GAGCTCAAGC TGCTCCTTTC 
TCGGCCATGG TTGCAACGGA GCTACGCTGT GTTTGCTTAA CCTTAGCTCC AAGAATTAAC 
CCCAAAATGA TCGCTAATTT GGAGGTGATC CCTGCAGGTC CACATTGCCC CAAGGTGGAA 
GTCATAGCTA AGTTGAAGAA CCAGAAGGAT AATGTTTGTC TTGACCCACA AGCTCCGTTG 
ATAAAGAAAG TCATTCAGAA AATATTGGGC AGTGAAAATA AGAAAACAAA GCGGAATGCA 
CTTGCACTGG TCAGATCAGC CAGTACTCAA TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071550.1
CDS	1..393
Translation	MSFQLRSSARIPSRSCSSFTLLAFLLLFTLPQHRAQAAPFSAMVATELRCVCLTLAPRINPKMIANLEVIPAGPHCPKVEVIAKLKNQKDNVCLDPQAPLIKKVIQKILGSENKKTKRNALALVRSASTQ

Target ORF information:

RefSeq Version	NM_022214.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus C-X-C motif chemokine ligand 6 (Cxcl6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022214.1

ORF Insert Sequence:

ATGAGCTTCC AGCTCCGCAG CTCCGCCCGC ATCCCTAGCC GGTCCTGCTC GTCATTCACC 
CTGCTGGCAT TTCTGCTGCT GTTCACACTG CCACAGCATC GAGCTCAAGC TGCTCCTTTC 
TCGGCCATGG TTGCAACGGA GCTACGCTGT GTTTGCTTAA CCTTAGCTCC AAGAATTAAC 
CCCAAAATGA TCGCTAATTT GGAGGTGATC CCTGCAGGTC CACATTGCCC CAAGGTGGAA 
GTCATAGCTA AGTTGAAGAA CCAGAAGGAT AATGTTTGTC TTGACCCACA AGCTCCGTTG 
ATAAAGAAAG TCATTCAGAA AATATTGGGC AGTGAAAATA AGAAAACAAA GCGGAATGCA 
CTTGCACTGG TCAGATCAGC CAGTACTCAA TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cxcl6 ( XM_017599366.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017454855.1 Rattus norvegicus C-X-C motif chemokine ligand 6 (Cxcl6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa43536
Clone ID Related Accession (Same CDS sequence)	XM_017599366.1 , XM_017599367.1 , XM_008770054.1
Accession Version	XM_017599366.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 429bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	C-X-C motif chemokine 5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005113.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGCTTCC AGCTCCGCAG CTCCGCCCGC ATCCCTAGCC GGTCCTGCTC GTCATTCACC 
CTGCTGGCAT TTCTGCTGCT GTTCACACTG CCACAGCATC GAGCTCAAGC TGCTCCTTTC 
TCGGCCATGG TTGCAACGGA GCTACGCTGT GTTTGCTTAA CCTTAGCTCC AAGAATTAAC 
CCCAAAATGA TCGCTAATTT GGAGGTGATC CCTGCAGGTC CACATTGCCC CAAGGTGGAA 
GTCATAGCTA AGTTGAAGAA CCAGAAGGAT AATGTTTGTC TTGACCCAGA AGCTCCGTTG 
ATAAAGAAAG TCATTCAGAA AATATTGGGC AGGTACTTGC TATCTTGGTC TCTGAGGTTT 
CTTGGTCTCT GCAGCGGGCA AGGTCGTTAT TCTCCGTGTA TGAGTTGGTG TTCTGGAACC 
ACATTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017454855.1
CDS	1197..1625
Translation	MSFQLRSSARIPSRSCSSFTLLAFLLLFTLPQHRAQAAPFSAMVATELRCVCLTLAPRINPKMIANLEVIPAGPHCPKVEVIAKLKNQKDNVCLDPEAPLIKKVIQKILGRYLLSWSLRFLGLCSGQGRYSPCMSWCSGTTF

Target ORF information:

RefSeq Version	XM_017599366.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus C-X-C motif chemokine ligand 6 (Cxcl6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017599366.1

ORF Insert Sequence:

ATGAGCTTCC AGCTCCGCAG CTCCGCCCGC ATCCCTAGCC GGTCCTGCTC GTCATTCACC 
CTGCTGGCAT TTCTGCTGCT GTTCACACTG CCACAGCATC GAGCTCAAGC TGCTCCTTTC 
TCGGCCATGG TTGCAACGGA GCTACGCTGT GTTTGCTTAA CCTTAGCTCC AAGAATTAAC 
CCCAAAATGA TCGCTAATTT GGAGGTGATC CCTGCAGGTC CACATTGCCC CAAGGTGGAA 
GTCATAGCTA AGTTGAAGAA CCAGAAGGAT AATGTTTGTC TTGACCCAGA AGCTCCGTTG 
ATAAAGAAAG TCATTCAGAA AATATTGGGC AGGTACTTGC TATCTTGGTC TCTGAGGTTT 
CTTGGTCTCT GCAGCGGGCA AGGTCGTTAT TCTCCGTGTA TGAGTTGGTG TTCTGGAACC 
ACATTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cxcl6 ( XM_017599367.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017454856.1 Rattus norvegicus C-X-C motif chemokine ligand 6 (Cxcl6), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa43536
Clone ID Related Accession (Same CDS sequence)	XM_017599366.1 , XM_017599367.1 , XM_008770054.1
Accession Version	XM_017599367.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 429bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	C-X-C motif chemokine 5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005113.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGCTTCC AGCTCCGCAG CTCCGCCCGC ATCCCTAGCC GGTCCTGCTC GTCATTCACC 
CTGCTGGCAT TTCTGCTGCT GTTCACACTG CCACAGCATC GAGCTCAAGC TGCTCCTTTC 
TCGGCCATGG TTGCAACGGA GCTACGCTGT GTTTGCTTAA CCTTAGCTCC AAGAATTAAC 
CCCAAAATGA TCGCTAATTT GGAGGTGATC CCTGCAGGTC CACATTGCCC CAAGGTGGAA 
GTCATAGCTA AGTTGAAGAA CCAGAAGGAT AATGTTTGTC TTGACCCAGA AGCTCCGTTG 
ATAAAGAAAG TCATTCAGAA AATATTGGGC AGGTACTTGC TATCTTGGTC TCTGAGGTTT 
CTTGGTCTCT GCAGCGGGCA AGGTCGTTAT TCTCCGTGTA TGAGTTGGTG TTCTGGAACC 
ACATTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017454856.1
CDS	215..643
Translation	MSFQLRSSARIPSRSCSSFTLLAFLLLFTLPQHRAQAAPFSAMVATELRCVCLTLAPRINPKMIANLEVIPAGPHCPKVEVIAKLKNQKDNVCLDPEAPLIKKVIQKILGRYLLSWSLRFLGLCSGQGRYSPCMSWCSGTTF

Target ORF information:

RefSeq Version	XM_017599367.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus C-X-C motif chemokine ligand 6 (Cxcl6), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017599367.1

ORF Insert Sequence:

ATGAGCTTCC AGCTCCGCAG CTCCGCCCGC ATCCCTAGCC GGTCCTGCTC GTCATTCACC 
CTGCTGGCAT TTCTGCTGCT GTTCACACTG CCACAGCATC GAGCTCAAGC TGCTCCTTTC 
TCGGCCATGG TTGCAACGGA GCTACGCTGT GTTTGCTTAA CCTTAGCTCC AAGAATTAAC 
CCCAAAATGA TCGCTAATTT GGAGGTGATC CCTGCAGGTC CACATTGCCC CAAGGTGGAA 
GTCATAGCTA AGTTGAAGAA CCAGAAGGAT AATGTTTGTC TTGACCCAGA AGCTCCGTTG 
ATAAAGAAAG TCATTCAGAA AATATTGGGC AGGTACTTGC TATCTTGGTC TCTGAGGTTT 
CTTGGTCTCT GCAGCGGGCA AGGTCGTTAT TCTCCGTGTA TGAGTTGGTG TTCTGGAACC 
ACATTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cxcl6 ( XM_008770054.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008768276.1 Rattus norvegicus C-X-C motif chemokine ligand 6 (Cxcl6), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa43536
Clone ID Related Accession (Same CDS sequence)	XM_017599366.1 , XM_017599367.1 , XM_008770054.1
Accession Version	XM_008770054.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 429bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	C-X-C motif chemokine 5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005113.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGCTTCC AGCTCCGCAG CTCCGCCCGC ATCCCTAGCC GGTCCTGCTC GTCATTCACC 
CTGCTGGCAT TTCTGCTGCT GTTCACACTG CCACAGCATC GAGCTCAAGC TGCTCCTTTC 
TCGGCCATGG TTGCAACGGA GCTACGCTGT GTTTGCTTAA CCTTAGCTCC AAGAATTAAC 
CCCAAAATGA TCGCTAATTT GGAGGTGATC CCTGCAGGTC CACATTGCCC CAAGGTGGAA 
GTCATAGCTA AGTTGAAGAA CCAGAAGGAT AATGTTTGTC TTGACCCAGA AGCTCCGTTG 
ATAAAGAAAG TCATTCAGAA AATATTGGGC AGGTACTTGC TATCTTGGTC TCTGAGGTTT 
CTTGGTCTCT GCAGCGGGCA AGGTCGTTAT TCTCCGTGTA TGAGTTGGTG TTCTGGAACC 
ACATTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008768276.1
CDS	418..846
Translation	MSFQLRSSARIPSRSCSSFTLLAFLLLFTLPQHRAQAAPFSAMVATELRCVCLTLAPRINPKMIANLEVIPAGPHCPKVEVIAKLKNQKDNVCLDPEAPLIKKVIQKILGRYLLSWSLRFLGLCSGQGRYSPCMSWCSGTTF

Target ORF information:

RefSeq Version	XM_008770054.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus C-X-C motif chemokine ligand 6 (Cxcl6), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008770054.1

ORF Insert Sequence:

ATGAGCTTCC AGCTCCGCAG CTCCGCCCGC ATCCCTAGCC GGTCCTGCTC GTCATTCACC 
CTGCTGGCAT TTCTGCTGCT GTTCACACTG CCACAGCATC GAGCTCAAGC TGCTCCTTTC 
TCGGCCATGG TTGCAACGGA GCTACGCTGT GTTTGCTTAA CCTTAGCTCC AAGAATTAAC 
CCCAAAATGA TCGCTAATTT GGAGGTGATC CCTGCAGGTC CACATTGCCC CAAGGTGGAA 
GTCATAGCTA AGTTGAAGAA CCAGAAGGAT AATGTTTGTC TTGACCCAGA AGCTCCGTTG 
ATAAAGAAAG TCATTCAGAA AATATTGGGC AGGTACTTGC TATCTTGGTC TCTGAGGTTT 
CTTGGTCTCT GCAGCGGGCA AGGTCGTTAT TCTCCGTGTA TGAGTTGGTG TTCTGGAACC 
ACATTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cxcl6 ( XM_017599368.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017454857.1 Rattus norvegicus C-X-C motif chemokine ligand 6 (Cxcl6), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa43537
Clone ID Related Accession (Same CDS sequence)	XM_017599368.1
Accession Version	XM_017599368.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 393bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	C-X-C motif chemokine 5 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005113.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGCTTCC AGCTCCGCAG CTCCGCCCGC ATCCCTAGCC GGTCCTGCTC GTCATTCACC 
CTGCTGGCAT TTCTGCTGCT GTTCACACTG CCACAGCATC GAGCTCAAGC TGCTCCTTTC 
TCGGCCATGG TTGCAACGGA GCTACGCTGT GTTTGCTTAA CCTTAGCTCC AAGAATTAAC 
CCCAAAATGA TCGCTAATTT GGAGGTGATC CCTGCAGGTC CACATTGCCC CAAGGTGGAA 
GTCATAGCTA AGTTGAAGAA CCAGAAGGAT AATGTTTGTC TTGACCCAGA AGCTCCGTTG 
ATAAAGAAAG TCATTCAGAA AATATTGGGC AGTGAAAATA AGAAAACAAA GCGGAATGCA 
CTTGCACTGG TCAGATCAGC CAGTACTCAA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017454857.1
CDS	1195..1587
Translation	MSFQLRSSARIPSRSCSSFTLLAFLLLFTLPQHRAQAAPFSAMVATELRCVCLTLAPRINPKMIANLEVIPAGPHCPKVEVIAKLKNQKDNVCLDPEAPLIKKVIQKILGSENKKTKRNALALVRSASTQ

Target ORF information:

RefSeq Version	XM_017599368.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus C-X-C motif chemokine ligand 6 (Cxcl6), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017599368.1

ORF Insert Sequence:

ATGAGCTTCC AGCTCCGCAG CTCCGCCCGC ATCCCTAGCC GGTCCTGCTC GTCATTCACC 
CTGCTGGCAT TTCTGCTGCT GTTCACACTG CCACAGCATC GAGCTCAAGC TGCTCCTTTC 
TCGGCCATGG TTGCAACGGA GCTACGCTGT GTTTGCTTAA CCTTAGCTCC AAGAATTAAC 
CCCAAAATGA TCGCTAATTT GGAGGTGATC CCTGCAGGTC CACATTGCCC CAAGGTGGAA 
GTCATAGCTA AGTTGAAGAA CCAGAAGGAT AATGTTTGTC TTGACCCAGA AGCTCCGTTG 
ATAAAGAAAG TCATTCAGAA AATATTGGGC AGTGAAAATA AGAAAACAAA GCGGAATGCA 
CTTGCACTGG TCAGATCAGC CAGTACTCAA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Corticotropin-Releasing Hormone Suppresses Synapse Formation in the Hippocampus of Male Rats via Inhibition of CXCL5 Secretion by Glia.
Endocrinology159(2)622-638(2018 Feb)
Zhang Y,Zheng Y,Xu Y,Sheng H,Ni X

Spinal CXCL5 contributes to nerve injury-induced neuropathic pain via modulating GSK-3? phosphorylation and activity in rats.
Neuroscience letters63452-59(2016 Nov)
Xu W,Zhu M,Yuan S,Yu W

JCV agnoprotein-induced reduction in CXCL5/LIX secretion by oligodendrocytes is associated with activation of apoptotic signaling in neurons.
Journal of cellular physiology227(8)3119-27(2012 Aug)
Merabova N,Kaminski R,Krynska B,Amini S,Khalili K,Darbinyan A

CXCL5 mediates UVB irradiation-induced pain.
Science translational medicine3(90)90ra60(2011 Jul)
Dawes JM,Calvo M,Perkins JR,Paterson KJ,Kiesewetter H,Hobbs C,Kaan TK,Orengo C,Bennett DL,McMahon SB

Adipose tissue-derived stem cells secrete CXCL5 cytokine with neurotrophic effects on cavernous nerve regeneration.
The journal of sexual medicine8(2)437-46(2011 Feb)
Zhang H,Yang R,Wang Z,Lin G,Lue TF,Lin CS

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Cxcl6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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