Hr cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Hr
Entrez Gene ID	60563
Full Name	HR, lysine demethylase and nuclear receptor corepressor
General protein information	Preferred Names HR, lysine demethylase and nuclear receptor corepressor Names lysine-specific demethylase hairless hair growth associated hairless homolog hairless protein protein hairless
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 15 Map Location: 15p11
Summary	This gene encodes a protein that is involved in hair growth. This protein functions as a transcriptional corepressor of multiple nuclear receptors, including thyroid hormone receptor, the retinoic acid receptor-related orphan receptors and the vitamin D receptors, and it interacts with histone deacetylases. The translation of this protein is modulated by a regulatory open reading frame (ORF) that exists upstream of the primary ORF. Mutations in this upstream ORF cause Marie Unna hereditary hypotrichosis (MUHH), an autosomal dominant form of genetic hair loss in human. [provided by RefSeq, Oct 2014].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006252283.2	XP_006252345.2	lysine-specific demethylase hairless isoform X1
NM_024364.3	NP_077340.3	lysine-specific demethylase hairless

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	HR	XP_519644.2
Bos taurus (cattle)	HR	NP_001096005.1
	HR	NP_001028015.1
Homo sapiens (human)	HR	NP_005135.2
Rattus norvegicus (Norway rat)	Hr	NP_077340.2
Canis lupus familiaris (dog)	HR	XP_543256.3
Mus musculus (house mouse)	Hr	NP_068677.2

Gene Ontology
Bibliography

Related articles in PubMed

Analysis of hairless corepressor mutants to characterize molecular cooperation with the vitamin D receptor in promoting the mammalian hair cycle.
Hsieh JC, Slater SA, Whitfield GK, Dawson JL, Hsieh G, Sheedy C, Haussler CA, Haussler MR
Journal of cellular biochemistry110(3)671-86(2010 Jun)

Loss-of-function mutations of an inhibitory upstream ORF in the human hairless transcript cause Marie Unna hereditary hypotrichosis.
Wen Y, Liu Y, Xu Y, Zhao Y, Hua R, Wang K, Sun M, Li Y, Yang S, Zhang XJ, Kruse R, Cichon S, Betz RC, N?then MM, van Steensel MA, van Geel M, Steijlen PM, Hohl D, Huber M, Dunnill GS, Kennedy C, Messenger A, Munro CS, Terrinoni A, Hovnanian A, Bodemer C, de Prost Y, Paller AS, Irvine AD, Sinclair R, Green J, Shang D, Liu Q, Luo Y, Jiang L, Chen HD, Lo WH, McLean WH, He CD, Zhang X
Nature genetics41(2)228-33(2009 Feb)

Physical and functional interaction between the vitamin D receptor and hairless corepressor, two proteins required for hair cycling.
Hsieh JC, Sisk JM, Jurutka PW, Haussler CA, Slater SA, Haussler MR, Thompson CC
The Journal of biological chemistry278(40)38665-74(2003 Oct)

Linkage mapping of the porcine hairless gene (HR ) to chromosome 14.
Fern?ndez A, Sili? L, Noguera JL, S?nchez A, Ovilo C
Animal genetics34(4)317-8(2003 Aug)

The thyroid hormone-regulated corepressor hairless associates with histone deacetylases in neonatal rat brain.
Potter GB, Zarach JM, Sisk JM, Thompson CC
Molecular endocrinology (Baltimore, Md.)16(11)2547-60(2002 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Hr and VDR interact via multiple protein-protein interfaces, catalyzing histone demethylation to effect chromatin remodeling and repress the transcription of VDR target genes that control the hair cycle.
Title: Analysis of hairless corepressor mutants to characterize molecular cooperation with the vitamin D receptor in promoting the mammalian hair cycle.

histopathologic changes in heterozygous and homozygous CR hairless rat mutants during the first month of life
Title: The Charles River "hairless" rat mutation is distinct from the hairless mouse alleles.

The following Hr gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Hr cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa13837	NM_024364.3 Latest version!	Rattus norvegicus HR, lysine demethylase and nuclear receptor corepressor (Hr), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$643.30 $919.00
ORa13837	XM_006252283.2 Latest version!	Rattus norvegicus hair growth associated (Hr), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$643.30 $919.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Hr ( NM_024364.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_077340.3 Rattus norvegicus HR, lysine demethylase and nuclear receptor corepressor (Hr), mRNA.

Price & Availability↑

CloneID	ORa13837
Clone ID Related Accession (Same CDS sequence)	XM_006252283.2 , NM_024364.3
Accession Version	NM_024364.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3546bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Rattus norvegicus(Norway rat)
Product	lysine-specific demethylase hairless
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CH473951.1. On or before Dec 15, 2013 this sequence version replaced XM_006252284.1, NM_024364.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: KR109217.1, U71293.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMD00052296, SAMN00632254 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## regulatory uORF :: PMID: 19122663 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAGAGTA TGCCCAGCTT CCTGAAGGAC ACCCCAGCCT GGGAGAAGAC TGCCCCTGTG 
AACGGCATTG TGGGACAGGA GCCTGGTACC TCCCCGCAGG ATGGCTTGCA CCATGGGGCA 
CTGTGCCTAG GAGAACCTGT TCCCTTTTGG AGGGGTGTTC TGAGCGCCCC AGACTCCTGG 
CTCCCTCCTG GCTTCCTCCA AGGCCCCAAG GACACACTCT CAGTGGTGGA GGGTGAGGGT 
TCTCGGAATG GGGAGAGGAA AGCCAACTGG CTGGGTAGCA AGGAGGGACT ACGCTGGAAG 
GAAGCGATGC TGGCCCATCC ACTGGCCTTC TGTGGGCCAG CATGCCCACC TCGCTATGGC 
CCCCTGATAC CTGAGCATAG CAGTGGCCAT CCCAAGAGTG ACCCTGTGGC CTTCCGGCCC 
TTGCACTGCC CTTTCCTGCT GGAGACCAAG ATTCTAGAGC GAGCTCCCTT CTGGGTTCCT 
ACCTGCTTGC CTCCCTACCT GATGTCCAGC CTGCCTCCAG AGCGTTCGTA TGACTGGCCT 
TTGGCCCCAA GCCCCTGGGT ATACTCTGGG AGCCAGCCAA AAGTGCCCTC TGCCTTCAGC 
TTAGGCAGCA AGGGCTTTTA CCACAAGGAT CCAAACATCC TCAGGCCAGC AAAGGAGCCC 
TTGGCAGCGT CAGAGTCTGG GATGTTGGGC TTAGCTCCTG GAGGGCATCT CCAGCAAGCC 
TGCGATGCAG AAGGCCCCTC GCTTCACCAG AGGGATGGGG AGACAGGAGC TGGCAGGCAG 
CAGAATCTTT GCCCAGTTTT CTTGGGGTAC CCAGACACTG TTCCTCGAAC CCCCTGGCCT 
TCTTGTCCCC CAGGCCTGGT TCACACTCTC GGTAACGTTT GGGCTGGGCC AGGAAGTAAC 
AGCTTTGGGT ACCAGCTAGG CCCACCAGTC ACACCAAGGT GCCCATCACC TGGGCCTCCC 
ACCCCTCCAG GGGGCTGTTG CTCATCCCAT CTGCCTGCCA GAGAGGGTGA TCCTGGCCCT 
TGTAGGAAAT GTCAGGATAG CCCAGAGGGA AGTAGCAGTG GGCCAGGGGA ATCCAGTGAA 
GAAAGAAACA AGGCTGGCTC CAGGGCCTCT CCTCCAAGCC ATCACACCAA GCTGAAAAAG 
ACCTGGCTCA CACGCCACTC GGAACAGTTC GAGTGCCCAG GTGGCTGTCC TGGGAAGGGA 
GAGAGCCCAG CCACTGGGCT CCGGGCACTC AAGAGGGCAG GCAGTCCAGA GGTCCAGGGA 
GCAAGGGGCC CGGCTCCCAA ACGCCCATCC CACACTTTCC CAGGTACTGG GAGGCAGGGG 
GCCAGGGCTT GGCAGGAGAC ACCAGAGACA TCCACAGGAA GCAAGGCAGA GGCACAGCAA 
CAAGAGGAGC AAAGAGGGCC CCGAGATGGC AGGATTCGGC TCCGGGAATC CAGACTTGAG 
GATACATCCT GCCAGCATCA CTTAGCAGGT GTCACTCAGT GCCCAAGCTG TGTCCAGGCA 
GCTGGAGAGG TGGAGATACT GACCAGCCAC TCCCAGAAAT CACATAGGTT ACCCCTGGAA 
GAGAAGCCGT TGGAGGAGGA TTCCTGTGCC ACTTCTGAGG AAGGAGGAGG GTCTAGCCCA 
GAAGCTTCCA TCAACAAGGG CCTAGCCAAG CATCTACTGA GTGGTCTGGG TGACCGACTC 
TGCCGCCTGC TGCGGAAGGA GCGGGAAGCC CTCGCCTGGG CACAGCGTGA AGGCCAGGGG 
CCAGCCATGA CAGAGGACAG CCCAGGCATT CCACACTGCT GCAGCCGTTG CCACCACGGA 
CTCTTCAACA CCCACTGGAG ATGTTCCCAC TGTAGCCACC GGCTGTGTGT AGCCTGTGGT 
CGCATAGCCG GAGCTGGGAA GAACAGGGAG AAAACAGGCT CTCGGGAGCA GCGCACAGAT 
GACTGTGCCC AGGAGGCTGG GCATGCTGCC TGTTCCCTGA TTCTGACCCA GTTTGTCTCC 
AGCCAGGCGC TGGCAGAACT GAGCACTGTG ATGCACCAAG TCTGGGCCAA GTTTGACATT 
CGGGGGCACT GTTTCTGTCA AGTCGATGCC CGTGTGTGGG CCCCCGGGGA TGGGGGTCAG 
CAGAAGGAAC CAACAGAGAA AACTCCCCCA GCTCCACAAC TTTCCTGCAA TGGAGATTCC 
AATCGGACCA AGGACATCAA AGAAGAGACC CCAGACTCCA CAGAGAGCCC AGCAGAGGAC 
CGTGCTGGCC GGTCACCACT TCCTTGTCCC TCTCTTTGTG AGCTGCTAGC CTCTACAGCT 
GTCAAACTCT GCCTGGGGCA TGAGCGGATT CACATGGCCT TTGCCCCGGT CACCCCGGCT 
CTGCCCAGTG ATGACCGCAT TACCAACATC CTGGACAGCA TTATTGCGCA GGTAGTAGAA 
CGGAAGATCC AAGAGAAAGC CCTGGGGCCA GGCCTTCGAG CAGGGTCAGG CTTACGAAAG 
GGCCTCAGCC TGCCCCTGTC ACCAGTGCGA ACCCGGTTGT CTCCTCCTGG AGCTCTGCTG 
TGGCTGCAAG AGCCCAGGCC TAAGCACGGC TTTCGTCTCT TCCAGGAGCA CTGGCGGCAG 
GGCCAGCCTG TGTTAGTATC AGGCATCCAG AAGACATTGA GACTTAGCCT GTGGGGAATG 
GAAGCCCTTG GGACACTTGG TGGCCAGGTG CAGACACTGA CTGCCCTTGG GCCGCCCCAA 
CCCACCAGCC TGGACAGCAC AGCATTCTGG AAGGGATTCT CTCATCCTGA GGCACGTCCA 
AAGTTAGATG AGGGCTCTGT CCTCCTGCTA CACCGACCCC TGGGGGATAA GGACGAGAGC 
AGGGTGGAGA ACCTTGCCTC CAGCCTTCCA CTCCCAGAGT ACTGTGCCCA CCAAGGGAAA 
CTCAACCTAG CGTCCTACCT CCCCCTGGGT CTCACACTGC ATCCACTGGA GCCCCAGCTC 
TGGGCAGCCT ATGGTGTGAA CTCGCACCGT GGACACCTGG GGACCAAGAA CCTATGTGTG 
GAGGTGTCTG ACCTAATCAG TATCCTGGTG CATGCTGAGG CACAGCTGCC TCCCTGGTAC 
CGAGCACAGA AAGATTTTCT CTCAGGCCTG GATGGGGAAG GGCTCTGGTC TCCAGGTAGC 
CAGACCAGCA CTGTGTGGCA TGTGTTCCGA GCCCAGGATG CCCAGCGTAT CCGTCGCTTT 
CTCCAGATGG TGTGCCCAGC TGGAGCAGGA ACCTTGGAGC CTGGTGCCCC AGGCAGCTGC 
TACTTGGATT CAGGGTTGCG ACGCAGGTTA AGGGAGGAGT GGGGTGTGAG CTGCTGGACA 
CTGCTGCAGG CTCCTGGAGA AGCGGTGCTG GTGCCTGCTG GGGCACCCCA TCAGGTACAG 
GGCTTGGTGA GCACAATCAG TGTCACTCAG CACTTTCTGT CTCCTGAGAC CTCGGCCCTC 
TCTGCTCAGC TCTGCCACCA GGGAGCCAGC CTGCCCCCTG ACCATCGTAT GCTTTATGCC 
CAGATGGACC GGGCTGTGTT CCAAGCAGTG AAGGTGGCGG TGGGGACATT ACAGGAAGCT 
AAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_077340.3
CDS	852..4397
Translation	MESMPSFLKDTPAWEKTAPVNGIVGQEPGTSPQDGLHHGALCLGEPVPFWRGVLSAPDSWLPPGFLQGPKDTLSVVEGEGSRNGERKANWLGSKEGLRWKEAMLAHPLAFCGPACPPRYGPLIPEHSSGHPKSDPVAFRPLHCPFLLETKILERAPFWVPTCLPPYLMSSLPPERSYDWPLAPSPWVYSGSQPKVPSAFSLGSKGFYHKDPNILRPAKEPLAASESGMLGLAPGGHLQQACDAEGPSLHQRDGETGAGRQQNLCPVFLGYPDTVPRTPWPSCPPGLVHTLGNVWAGPGSNSFGYQLGPPVTPRCPSPGPPTPPGGCCSSHLPAREGDPGPCRKCQDSPEGSSSGPGESSEERNKAGSRASPPSHHTKLKKTWLTRHSEQFECPGGCPGKGESPATGLRALKRAGSPEVQGARGPAPKRPSHTFPGTGRQGARAWQETPETSTGSKAEAQQQEEQRGPRDGRIRLRESRLEDTSCQHHLAGVTQCPSCVQAAGEVEILTSHSQKSHRLPLEEKPLEEDSCATSEEGGGSSPEASINKGLAKHLLSGLGDRLCRLLRKEREALAWAQREGQGPAMTEDSPGIPHCCSRCHHGLFNTHWRCSHCSHRLCVACGRIAGAGKNREKTGSREQRTDDCAQEAGHAACSLILTQFVSSQALAELSTVMHQVWAKFDIRGHCFCQVDARVWAPGDGGQQKEPTEKTPPAPQLSCNGDSNRTKDIKEETPDSTESPAEDRAGRSPLPCPSLCELLASTAVKLCLGHERIHMAFAPVTPALPSDDRITNILDSIIAQVVERKIQEKALGPGLRAGSGLRKGLSLPLSPVRTRLSPPGALLWLQEPRPKHGFRLFQEHWRQGQPVLVSGIQKTLRLSLWGMEALGTLGGQVQTLTALGPPQPTSLDSTAFWKGFSHPEARPKLDEGSVLLLHRPLGDKDESRVENLASSLPLPEYCAHQGKLNLASYLPLGLTLHPLEPQLWAAYGVNSHRGHLGTKNLCVEVSDLISILVHAEAQLPPWYRAQKDFLSGLDGEGLWSPGSQTSTVWHVFRAQDAQRIRRFLQMVCPAGAGTLEPGAPGSCYLDSGLRRRLREEWGVSCWTLLQAPGEAVLVPAGAPHQVQGLVSTISVTQHFLSPETSALSAQLCHQGASLPPDHRMLYAQMDRAVFQAVKVAVGTLQEAK

Target ORF information:

RefSeq Version	NM_024364.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus HR, lysine demethylase and nuclear receptor corepressor (Hr), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024364.3

ORF Insert Sequence:

ATGGAGAGTA TGCCCAGCTT CCTGAAGGAC ACCCCAGCCT GGGAGAAGAC TGCCCCTGTG 
AACGGCATTG TGGGACAGGA GCCTGGTACC TCCCCGCAGG ATGGCTTGCA CCATGGGGCA 
CTGTGCCTAG GAGAACCTGT TCCCTTTTGG AGGGGTGTTC TGAGCGCCCC AGACTCCTGG 
CTCCCTCCTG GCTTCCTCCA AGGCCCCAAG GACACACTCT CAGTGGTGGA GGGTGAGGGT 
TCTCGGAATG GGGAGAGGAA AGCCAACTGG CTGGGTAGCA AGGAGGGACT ACGCTGGAAG 
GAAGCGATGC TGGCCCATCC ACTGGCCTTC TGTGGGCCAG CATGCCCACC TCGCTATGGC 
CCCCTGATAC CTGAGCATAG CAGTGGCCAT CCCAAGAGTG ACCCTGTGGC CTTCCGGCCC 
TTGCACTGCC CTTTCCTGCT GGAGACCAAG ATTCTAGAGC GAGCTCCCTT CTGGGTTCCT 
ACCTGCTTGC CTCCCTACCT GATGTCCAGC CTGCCTCCAG AGCGTTCGTA TGACTGGCCT 
TTGGCCCCAA GCCCCTGGGT ATACTCTGGG AGCCAGCCAA AAGTGCCCTC TGCCTTCAGC 
TTAGGCAGCA AGGGCTTTTA CCACAAGGAT CCAAACATCC TCAGGCCAGC AAAGGAGCCC 
TTGGCAGCGT CAGAGTCTGG GATGTTGGGC TTAGCTCCTG GAGGGCATCT CCAGCAAGCC 
TGCGATGCAG AAGGCCCCTC GCTTCACCAG AGGGATGGGG AGACAGGAGC TGGCAGGCAG 
CAGAATCTTT GCCCAGTTTT CTTGGGGTAC CCAGACACTG TTCCTCGAAC CCCCTGGCCT 
TCTTGTCCCC CAGGCCTGGT TCACACTCTC GGTAACGTTT GGGCTGGGCC AGGAAGTAAC 
AGCTTTGGGT ACCAGCTAGG CCCACCAGTC ACACCAAGGT GCCCATCACC TGGGCCTCCC 
ACCCCTCCAG GGGGCTGTTG CTCATCCCAT CTGCCTGCCA GAGAGGGTGA TCCTGGCCCT 
TGTAGGAAAT GTCAGGATAG CCCAGAGGGA AGTAGCAGTG GGCCAGGGGA ATCCAGTGAA 
GAAAGAAACA AGGCTGGCTC CAGGGCCTCT CCTCCAAGCC ATCACACCAA GCTGAAAAAG 
ACCTGGCTCA CACGCCACTC GGAACAGTTC GAGTGCCCAG GTGGCTGTCC TGGGAAGGGA 
GAGAGCCCAG CCACTGGGCT CCGGGCACTC AAGAGGGCAG GCAGTCCAGA GGTCCAGGGA 
GCAAGGGGCC CGGCTCCCAA ACGCCCATCC CACACTTTCC CAGGTACTGG GAGGCAGGGG 
GCCAGGGCTT GGCAGGAGAC ACCAGAGACA TCCACAGGAA GCAAGGCAGA GGCACAGCAA 
CAAGAGGAGC AAAGAGGGCC CCGAGATGGC AGGATTCGGC TCCGGGAATC CAGACTTGAG 
GATACATCCT GCCAGCATCA CTTAGCAGGT GTCACTCAGT GCCCAAGCTG TGTCCAGGCA 
GCTGGAGAGG TGGAGATACT GACCAGCCAC TCCCAGAAAT CACATAGGTT ACCCCTGGAA 
GAGAAGCCGT TGGAGGAGGA TTCCTGTGCC ACTTCTGAGG AAGGAGGAGG GTCTAGCCCA 
GAAGCTTCCA TCAACAAGGG CCTAGCCAAG CATCTACTGA GTGGTCTGGG TGACCGACTC 
TGCCGCCTGC TGCGGAAGGA GCGGGAAGCC CTCGCCTGGG CACAGCGTGA AGGCCAGGGG 
CCAGCCATGA CAGAGGACAG CCCAGGCATT CCACACTGCT GCAGCCGTTG CCACCACGGA 
CTCTTCAACA CCCACTGGAG ATGTTCCCAC TGTAGCCACC GGCTGTGTGT AGCCTGTGGT 
CGCATAGCCG GAGCTGGGAA GAACAGGGAG AAAACAGGCT CTCGGGAGCA GCGCACAGAT 
GACTGTGCCC AGGAGGCTGG GCATGCTGCC TGTTCCCTGA TTCTGACCCA GTTTGTCTCC 
AGCCAGGCGC TGGCAGAACT GAGCACTGTG ATGCACCAAG TCTGGGCCAA GTTTGACATT 
CGGGGGCACT GTTTCTGTCA AGTCGATGCC CGTGTGTGGG CCCCCGGGGA TGGGGGTCAG 
CAGAAGGAAC CAACAGAGAA AACTCCCCCA GCTCCACAAC TTTCCTGCAA TGGAGATTCC 
AATCGGACCA AGGACATCAA AGAAGAGACC CCAGACTCCA CAGAGAGCCC AGCAGAGGAC 
CGTGCTGGCC GGTCACCACT TCCTTGTCCC TCTCTTTGTG AGCTGCTAGC CTCTACAGCT 
GTCAAACTCT GCCTGGGGCA TGAGCGGATT CACATGGCCT TTGCCCCGGT CACCCCGGCT 
CTGCCCAGTG ATGACCGCAT TACCAACATC CTGGACAGCA TTATTGCGCA GGTAGTAGAA 
CGGAAGATCC AAGAGAAAGC CCTGGGGCCA GGCCTTCGAG CAGGGTCAGG CTTACGAAAG 
GGCCTCAGCC TGCCCCTGTC ACCAGTGCGA ACCCGGTTGT CTCCTCCTGG AGCTCTGCTG 
TGGCTGCAAG AGCCCAGGCC TAAGCACGGC TTTCGTCTCT TCCAGGAGCA CTGGCGGCAG 
GGCCAGCCTG TGTTAGTATC AGGCATCCAG AAGACATTGA GACTTAGCCT GTGGGGAATG 
GAAGCCCTTG GGACACTTGG TGGCCAGGTG CAGACACTGA CTGCCCTTGG GCCGCCCCAA 
CCCACCAGCC TGGACAGCAC AGCATTCTGG AAGGGATTCT CTCATCCTGA GGCACGTCCA 
AAGTTAGATG AGGGCTCTGT CCTCCTGCTA CACCGACCCC TGGGGGATAA GGACGAGAGC 
AGGGTGGAGA ACCTTGCCTC CAGCCTTCCA CTCCCAGAGT ACTGTGCCCA CCAAGGGAAA 
CTCAACCTAG CGTCCTACCT CCCCCTGGGT CTCACACTGC ATCCACTGGA GCCCCAGCTC 
TGGGCAGCCT ATGGTGTGAA CTCGCACCGT GGACACCTGG GGACCAAGAA CCTATGTGTG 
GAGGTGTCTG ACCTAATCAG TATCCTGGTG CATGCTGAGG CACAGCTGCC TCCCTGGTAC 
CGAGCACAGA AAGATTTTCT CTCAGGCCTG GATGGGGAAG GGCTCTGGTC TCCAGGTAGC 
CAGACCAGCA CTGTGTGGCA TGTGTTCCGA GCCCAGGATG CCCAGCGTAT CCGTCGCTTT 
CTCCAGATGG TGTGCCCAGC TGGAGCAGGA ACCTTGGAGC CTGGTGCCCC AGGCAGCTGC 
TACTTGGATT CAGGGTTGCG ACGCAGGTTA AGGGAGGAGT GGGGTGTGAG CTGCTGGACA 
CTGCTGCAGG CTCCTGGAGA AGCGGTGCTG GTGCCTGCTG GGGCACCCCA TCAGGTACAG 
GGCTTGGTGA GCACAATCAG TGTCACTCAG CACTTTCTGT CTCCTGAGAC CTCGGCCCTC 
TCTGCTCAGC TCTGCCACCA GGGAGCCAGC CTGCCCCCTG ACCATCGTAT GCTTTATGCC 
CAGATGGACC GGGCTGTGTT CCAAGCAGTG AAGGTGGCGG TGGGGACATT ACAGGAAGCT 
AAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Hr ( XM_006252283.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006252345.2 Rattus norvegicus hair growth associated (Hr), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa13837
Clone ID Related Accession (Same CDS sequence)	XM_006252283.2 , NM_024364.3
Accession Version	XM_006252283.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3546bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	lysine-specific demethylase hairless isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005114.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006252283.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGAGTA TGCCCAGCTT CCTGAAGGAC ACCCCAGCCT GGGAGAAGAC TGCCCCTGTG 
AACGGCATTG TGGGACAGGA GCCTGGTACC TCCCCGCAGG ATGGCTTGCA CCATGGGGCA 
CTGTGCCTAG GAGAACCTGT TCCCTTTTGG AGGGGTGTTC TGAGCGCCCC AGACTCCTGG 
CTCCCTCCTG GCTTCCTCCA AGGCCCCAAG GACACACTCT CAGTGGTGGA GGGTGAGGGT 
TCTCGGAATG GGGAGAGGAA AGCCAACTGG CTGGGTAGCA AGGAGGGACT ACGCTGGAAG 
GAAGCGATGC TGGCCCATCC ACTGGCCTTC TGTGGGCCAG CATGCCCACC TCGCTATGGC 
CCCCTGATAC CTGAGCATAG CAGTGGCCAT CCCAAGAGTG ACCCTGTGGC CTTCCGGCCC 
TTGCACTGCC CTTTCCTGCT GGAGACCAAG ATTCTAGAGC GAGCTCCCTT CTGGGTTCCT 
ACCTGCTTGC CTCCCTACCT GATGTCCAGC CTGCCTCCAG AGCGTTCGTA TGACTGGCCT 
TTGGCCCCAA GCCCCTGGGT ATACTCTGGG AGCCAGCCAA AAGTGCCCTC TGCCTTCAGC 
TTAGGCAGCA AGGGCTTTTA CCACAAGGAT CCAAACATCC TCAGGCCAGC AAAGGAGCCC 
TTGGCAGCGT CAGAGTCTGG GATGTTGGGC TTAGCTCCTG GAGGGCATCT CCAGCAAGCC 
TGCGATGCAG AAGGCCCCTC GCTTCACCAG AGGGATGGGG AGACAGGAGC TGGCAGGCAG 
CAGAATCTTT GCCCAGTTTT CTTGGGGTAC CCAGACACTG TTCCTCGAAC CCCCTGGCCT 
TCTTGTCCCC CAGGCCTGGT TCACACTCTC GGTAACGTTT GGGCTGGGCC AGGAAGTAAC 
AGCTTTGGGT ACCAGCTAGG CCCACCAGTC ACACCAAGGT GCCCATCACC TGGGCCTCCC 
ACCCCTCCAG GGGGCTGTTG CTCATCCCAT CTGCCTGCCA GAGAGGGTGA TCCTGGCCCT 
TGTAGGAAAT GTCAGGATAG CCCAGAGGGA AGTAGCAGTG GGCCAGGGGA ATCCAGTGAA 
GAAAGAAACA AGGCTGGCTC CAGGGCCTCT CCTCCAAGCC ATCACACCAA GCTGAAAAAG 
ACCTGGCTCA CACGCCACTC GGAACAGTTC GAGTGCCCAG GTGGCTGTCC TGGGAAGGGA 
GAGAGCCCAG CCACTGGGCT CCGGGCACTC AAGAGGGCAG GCAGTCCAGA GGTCCAGGGA 
GCAAGGGGCC CGGCTCCCAA ACGCCCATCC CACACTTTCC CAGGTACTGG GAGGCAGGGG 
GCCAGGGCTT GGCAGGAGAC ACCAGAGACA TCCACAGGAA GCAAGGCAGA GGCACAGCAA 
CAAGAGGAGC AAAGAGGGCC CCGAGATGGC AGGATTCGGC TCCGGGAATC CAGACTTGAG 
GATACATCCT GCCAGCATCA CTTAGCAGGT GTCACTCAGT GCCCAAGCTG TGTCCAGGCA 
GCTGGAGAGG TGGAGATACT GACCAGCCAC TCCCAGAAAT CACATAGGTT ACCCCTGGAA 
GAGAAGCCGT TGGAGGAGGA TTCCTGTGCC ACTTCTGAGG AAGGAGGAGG GTCTAGCCCA 
GAAGCTTCCA TCAACAAGGG CCTAGCCAAG CATCTACTGA GTGGTCTGGG TGACCGACTC 
TGCCGCCTGC TGCGGAAGGA GCGGGAAGCC CTCGCCTGGG CACAGCGTGA AGGCCAGGGG 
CCAGCCATGA CAGAGGACAG CCCAGGCATT CCACACTGCT GCAGCCGTTG CCACCACGGA 
CTCTTCAACA CCCACTGGAG ATGTTCCCAC TGTAGCCACC GGCTGTGTGT AGCCTGTGGT 
CGCATAGCCG GAGCTGGGAA GAACAGGGAG AAAACAGGCT CTCGGGAGCA GCGCACAGAT 
GACTGTGCCC AGGAGGCTGG GCATGCTGCC TGTTCCCTGA TTCTGACCCA GTTTGTCTCC 
AGCCAGGCGC TGGCAGAACT GAGCACTGTG ATGCACCAAG TCTGGGCCAA GTTTGACATT 
CGGGGGCACT GTTTCTGTCA AGTCGATGCC CGTGTGTGGG CCCCCGGGGA TGGGGGTCAG 
CAGAAGGAAC CAACAGAGAA AACTCCCCCA GCTCCACAAC TTTCCTGCAA TGGAGATTCC 
AATCGGACCA AGGACATCAA AGAAGAGACC CCAGACTCCA CAGAGAGCCC AGCAGAGGAC 
CGTGCTGGCC GGTCACCACT TCCTTGTCCC TCTCTTTGTG AGCTGCTAGC CTCTACAGCT 
GTCAAACTCT GCCTGGGGCA TGAGCGGATT CACATGGCCT TTGCCCCGGT CACCCCGGCT 
CTGCCCAGTG ATGACCGCAT TACCAACATC CTGGACAGCA TTATTGCGCA GGTAGTAGAA 
CGGAAGATCC AAGAGAAAGC CCTGGGGCCA GGCCTTCGAG CAGGGTCAGG CTTACGAAAG 
GGCCTCAGCC TGCCCCTGTC ACCAGTGCGA ACCCGGTTGT CTCCTCCTGG AGCTCTGCTG 
TGGCTGCAAG AGCCCAGGCC TAAGCACGGC TTTCGTCTCT TCCAGGAGCA CTGGCGGCAG 
GGCCAGCCTG TGTTAGTATC AGGCATCCAG AAGACATTGA GACTTAGCCT GTGGGGAATG 
GAAGCCCTTG GGACACTTGG TGGCCAGGTG CAGACACTGA CTGCCCTTGG GCCGCCCCAA 
CCCACCAGCC TGGACAGCAC AGCATTCTGG AAGGGATTCT CTCATCCTGA GGCACGTCCA 
AAGTTAGATG AGGGCTCTGT CCTCCTGCTA CACCGACCCC TGGGGGATAA GGACGAGAGC 
AGGGTGGAGA ACCTTGCCTC CAGCCTTCCA CTCCCAGAGT ACTGTGCCCA CCAAGGGAAA 
CTCAACCTAG CGTCCTACCT CCCCCTGGGT CTCACACTGC ATCCACTGGA GCCCCAGCTC 
TGGGCAGCCT ATGGTGTGAA CTCGCACCGT GGACACCTGG GGACCAAGAA CCTATGTGTG 
GAGGTGTCTG ACCTAATCAG TATCCTGGTG CATGCTGAGG CACAGCTGCC TCCCTGGTAC 
CGAGCACAGA AAGATTTTCT CTCAGGCCTG GATGGGGAAG GGCTCTGGTC TCCAGGTAGC 
CAGACCAGCA CTGTGTGGCA TGTGTTCCGA GCCCAGGATG CCCAGCGTAT CCGTCGCTTT 
CTCCAGATGG TGTGCCCAGC TGGAGCAGGA ACCTTGGAGC CTGGTGCCCC AGGCAGCTGC 
TACTTGGATT CAGGGTTGCG ACGCAGGTTA AGGGAGGAGT GGGGTGTGAG CTGCTGGACA 
CTGCTGCAGG CTCCTGGAGA AGCGGTGCTG GTGCCTGCTG GGGCACCCCA TCAGGTACAG 
GGCTTGGTGA GCACAATCAG TGTCACTCAG CACTTTCTGT CTCCTGAGAC CTCGGCCCTC 
TCTGCTCAGC TCTGCCACCA GGGAGCCAGC CTGCCCCCTG ACCATCGTAT GCTTTATGCC 
CAGATGGACC GGGCTGTGTT CCAAGCAGTG AAGGTGGCGG TGGGGACATT ACAGGAAGCT 
AAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006252345.2
CDS	57..3602
Translation	MESMPSFLKDTPAWEKTAPVNGIVGQEPGTSPQDGLHHGALCLGEPVPFWRGVLSAPDSWLPPGFLQGPKDTLSVVEGEGSRNGERKANWLGSKEGLRWKEAMLAHPLAFCGPACPPRYGPLIPEHSSGHPKSDPVAFRPLHCPFLLETKILERAPFWVPTCLPPYLMSSLPPERSYDWPLAPSPWVYSGSQPKVPSAFSLGSKGFYHKDPNILRPAKEPLAASESGMLGLAPGGHLQQACDAEGPSLHQRDGETGAGRQQNLCPVFLGYPDTVPRTPWPSCPPGLVHTLGNVWAGPGSNSFGYQLGPPVTPRCPSPGPPTPPGGCCSSHLPAREGDPGPCRKCQDSPEGSSSGPGESSEERNKAGSRASPPSHHTKLKKTWLTRHSEQFECPGGCPGKGESPATGLRALKRAGSPEVQGARGPAPKRPSHTFPGTGRQGARAWQETPETSTGSKAEAQQQEEQRGPRDGRIRLRESRLEDTSCQHHLAGVTQCPSCVQAAGEVEILTSHSQKSHRLPLEEKPLEEDSCATSEEGGGSSPEASINKGLAKHLLSGLGDRLCRLLRKEREALAWAQREGQGPAMTEDSPGIPHCCSRCHHGLFNTHWRCSHCSHRLCVACGRIAGAGKNREKTGSREQRTDDCAQEAGHAACSLILTQFVSSQALAELSTVMHQVWAKFDIRGHCFCQVDARVWAPGDGGQQKEPTEKTPPAPQLSCNGDSNRTKDIKEETPDSTESPAEDRAGRSPLPCPSLCELLASTAVKLCLGHERIHMAFAPVTPALPSDDRITNILDSIIAQVVERKIQEKALGPGLRAGSGLRKGLSLPLSPVRTRLSPPGALLWLQEPRPKHGFRLFQEHWRQGQPVLVSGIQKTLRLSLWGMEALGTLGGQVQTLTALGPPQPTSLDSTAFWKGFSHPEARPKLDEGSVLLLHRPLGDKDESRVENLASSLPLPEYCAHQGKLNLASYLPLGLTLHPLEPQLWAAYGVNSHRGHLGTKNLCVEVSDLISILVHAEAQLPPWYRAQKDFLSGLDGEGLWSPGSQTSTVWHVFRAQDAQRIRRFLQMVCPAGAGTLEPGAPGSCYLDSGLRRRLREEWGVSCWTLLQAPGEAVLVPAGAPHQVQGLVSTISVTQHFLSPETSALSAQLCHQGASLPPDHRMLYAQMDRAVFQAVKVAVGTLQEAK

Target ORF information:

RefSeq Version	XM_006252283.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus hair growth associated (Hr), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006252283.2

ORF Insert Sequence:

ATGGAGAGTA TGCCCAGCTT CCTGAAGGAC ACCCCAGCCT GGGAGAAGAC TGCCCCTGTG 
AACGGCATTG TGGGACAGGA GCCTGGTACC TCCCCGCAGG ATGGCTTGCA CCATGGGGCA 
CTGTGCCTAG GAGAACCTGT TCCCTTTTGG AGGGGTGTTC TGAGCGCCCC AGACTCCTGG 
CTCCCTCCTG GCTTCCTCCA AGGCCCCAAG GACACACTCT CAGTGGTGGA GGGTGAGGGT 
TCTCGGAATG GGGAGAGGAA AGCCAACTGG CTGGGTAGCA AGGAGGGACT ACGCTGGAAG 
GAAGCGATGC TGGCCCATCC ACTGGCCTTC TGTGGGCCAG CATGCCCACC TCGCTATGGC 
CCCCTGATAC CTGAGCATAG CAGTGGCCAT CCCAAGAGTG ACCCTGTGGC CTTCCGGCCC 
TTGCACTGCC CTTTCCTGCT GGAGACCAAG ATTCTAGAGC GAGCTCCCTT CTGGGTTCCT 
ACCTGCTTGC CTCCCTACCT GATGTCCAGC CTGCCTCCAG AGCGTTCGTA TGACTGGCCT 
TTGGCCCCAA GCCCCTGGGT ATACTCTGGG AGCCAGCCAA AAGTGCCCTC TGCCTTCAGC 
TTAGGCAGCA AGGGCTTTTA CCACAAGGAT CCAAACATCC TCAGGCCAGC AAAGGAGCCC 
TTGGCAGCGT CAGAGTCTGG GATGTTGGGC TTAGCTCCTG GAGGGCATCT CCAGCAAGCC 
TGCGATGCAG AAGGCCCCTC GCTTCACCAG AGGGATGGGG AGACAGGAGC TGGCAGGCAG 
CAGAATCTTT GCCCAGTTTT CTTGGGGTAC CCAGACACTG TTCCTCGAAC CCCCTGGCCT 
TCTTGTCCCC CAGGCCTGGT TCACACTCTC GGTAACGTTT GGGCTGGGCC AGGAAGTAAC 
AGCTTTGGGT ACCAGCTAGG CCCACCAGTC ACACCAAGGT GCCCATCACC TGGGCCTCCC 
ACCCCTCCAG GGGGCTGTTG CTCATCCCAT CTGCCTGCCA GAGAGGGTGA TCCTGGCCCT 
TGTAGGAAAT GTCAGGATAG CCCAGAGGGA AGTAGCAGTG GGCCAGGGGA ATCCAGTGAA 
GAAAGAAACA AGGCTGGCTC CAGGGCCTCT CCTCCAAGCC ATCACACCAA GCTGAAAAAG 
ACCTGGCTCA CACGCCACTC GGAACAGTTC GAGTGCCCAG GTGGCTGTCC TGGGAAGGGA 
GAGAGCCCAG CCACTGGGCT CCGGGCACTC AAGAGGGCAG GCAGTCCAGA GGTCCAGGGA 
GCAAGGGGCC CGGCTCCCAA ACGCCCATCC CACACTTTCC CAGGTACTGG GAGGCAGGGG 
GCCAGGGCTT GGCAGGAGAC ACCAGAGACA TCCACAGGAA GCAAGGCAGA GGCACAGCAA 
CAAGAGGAGC AAAGAGGGCC CCGAGATGGC AGGATTCGGC TCCGGGAATC CAGACTTGAG 
GATACATCCT GCCAGCATCA CTTAGCAGGT GTCACTCAGT GCCCAAGCTG TGTCCAGGCA 
GCTGGAGAGG TGGAGATACT GACCAGCCAC TCCCAGAAAT CACATAGGTT ACCCCTGGAA 
GAGAAGCCGT TGGAGGAGGA TTCCTGTGCC ACTTCTGAGG AAGGAGGAGG GTCTAGCCCA 
GAAGCTTCCA TCAACAAGGG CCTAGCCAAG CATCTACTGA GTGGTCTGGG TGACCGACTC 
TGCCGCCTGC TGCGGAAGGA GCGGGAAGCC CTCGCCTGGG CACAGCGTGA AGGCCAGGGG 
CCAGCCATGA CAGAGGACAG CCCAGGCATT CCACACTGCT GCAGCCGTTG CCACCACGGA 
CTCTTCAACA CCCACTGGAG ATGTTCCCAC TGTAGCCACC GGCTGTGTGT AGCCTGTGGT 
CGCATAGCCG GAGCTGGGAA GAACAGGGAG AAAACAGGCT CTCGGGAGCA GCGCACAGAT 
GACTGTGCCC AGGAGGCTGG GCATGCTGCC TGTTCCCTGA TTCTGACCCA GTTTGTCTCC 
AGCCAGGCGC TGGCAGAACT GAGCACTGTG ATGCACCAAG TCTGGGCCAA GTTTGACATT 
CGGGGGCACT GTTTCTGTCA AGTCGATGCC CGTGTGTGGG CCCCCGGGGA TGGGGGTCAG 
CAGAAGGAAC CAACAGAGAA AACTCCCCCA GCTCCACAAC TTTCCTGCAA TGGAGATTCC 
AATCGGACCA AGGACATCAA AGAAGAGACC CCAGACTCCA CAGAGAGCCC AGCAGAGGAC 
CGTGCTGGCC GGTCACCACT TCCTTGTCCC TCTCTTTGTG AGCTGCTAGC CTCTACAGCT 
GTCAAACTCT GCCTGGGGCA TGAGCGGATT CACATGGCCT TTGCCCCGGT CACCCCGGCT 
CTGCCCAGTG ATGACCGCAT TACCAACATC CTGGACAGCA TTATTGCGCA GGTAGTAGAA 
CGGAAGATCC AAGAGAAAGC CCTGGGGCCA GGCCTTCGAG CAGGGTCAGG CTTACGAAAG 
GGCCTCAGCC TGCCCCTGTC ACCAGTGCGA ACCCGGTTGT CTCCTCCTGG AGCTCTGCTG 
TGGCTGCAAG AGCCCAGGCC TAAGCACGGC TTTCGTCTCT TCCAGGAGCA CTGGCGGCAG 
GGCCAGCCTG TGTTAGTATC AGGCATCCAG AAGACATTGA GACTTAGCCT GTGGGGAATG 
GAAGCCCTTG GGACACTTGG TGGCCAGGTG CAGACACTGA CTGCCCTTGG GCCGCCCCAA 
CCCACCAGCC TGGACAGCAC AGCATTCTGG AAGGGATTCT CTCATCCTGA GGCACGTCCA 
AAGTTAGATG AGGGCTCTGT CCTCCTGCTA CACCGACCCC TGGGGGATAA GGACGAGAGC 
AGGGTGGAGA ACCTTGCCTC CAGCCTTCCA CTCCCAGAGT ACTGTGCCCA CCAAGGGAAA 
CTCAACCTAG CGTCCTACCT CCCCCTGGGT CTCACACTGC ATCCACTGGA GCCCCAGCTC 
TGGGCAGCCT ATGGTGTGAA CTCGCACCGT GGACACCTGG GGACCAAGAA CCTATGTGTG 
GAGGTGTCTG ACCTAATCAG TATCCTGGTG CATGCTGAGG CACAGCTGCC TCCCTGGTAC 
CGAGCACAGA AAGATTTTCT CTCAGGCCTG GATGGGGAAG GGCTCTGGTC TCCAGGTAGC 
CAGACCAGCA CTGTGTGGCA TGTGTTCCGA GCCCAGGATG CCCAGCGTAT CCGTCGCTTT 
CTCCAGATGG TGTGCCCAGC TGGAGCAGGA ACCTTGGAGC CTGGTGCCCC AGGCAGCTGC 
TACTTGGATT CAGGGTTGCG ACGCAGGTTA AGGGAGGAGT GGGGTGTGAG CTGCTGGACA 
CTGCTGCAGG CTCCTGGAGA AGCGGTGCTG GTGCCTGCTG GGGCACCCCA TCAGGTACAG 
GGCTTGGTGA GCACAATCAG TGTCACTCAG CACTTTCTGT CTCCTGAGAC CTCGGCCCTC 
TCTGCTCAGC TCTGCCACCA GGGAGCCAGC CTGCCCCCTG ACCATCGTAT GCTTTATGCC 
CAGATGGACC GGGCTGTGTT CCAAGCAGTG AAGGTGGCGG TGGGGACATT ACAGGAAGCT 
AAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Analysis of hairless corepressor mutants to characterize molecular cooperation with the vitamin D receptor in promoting the mammalian hair cycle.
Journal of cellular biochemistry110(3)671-86(2010 Jun)
Hsieh JC,Slater SA,Whitfield GK,Dawson JL,Hsieh G,Sheedy C,Haussler CA,Haussler MR

Loss-of-function mutations of an inhibitory upstream ORF in the human hairless transcript cause Marie Unna hereditary hypotrichosis.
Nature genetics41(2)228-33(2009 Feb)
Wen Y,Liu Y,Xu Y,Zhao Y,Hua R,Wang K,Sun M,Li Y,Yang S,Zhang XJ,Kruse R,Cichon S,Betz RC,N?then MM,van Steensel MA,van Geel M,Steijlen PM,Hohl D,Huber M,Dunnill GS,Kennedy C,Messenger A,Munro CS,Terrinoni A,Hovnanian A,Bodemer C,de Prost Y,Paller AS,Irvine AD,Sinclair R,Green J,Shang D,Liu Q,Luo Y,Jiang L,Chen HD,Lo WH,McLean WH,He CD,Zhang X

Physical and functional interaction between the vitamin D receptor and hairless corepressor, two proteins required for hair cycling.
The Journal of biological chemistry278(40)38665-74(2003 Oct)
Hsieh JC,Sisk JM,Jurutka PW,Haussler CA,Slater SA,Haussler MR,Thompson CC

Linkage mapping of the porcine hairless gene (HR ) to chromosome 14.
Animal genetics34(4)317-8(2003 Aug)
Fern?ndez A,Sili? L,Noguera JL,S?nchez A,Ovilo C

The thyroid hormone-regulated corepressor hairless associates with histone deacetylases in neonatal rat brain.
Molecular endocrinology (Baltimore, Md.)16(11)2547-60(2002 Nov)
Potter GB,Zarach JM,Sisk JM,Thompson CC

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Hr cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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