Olig1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Olig1
Entrez Gene ID	60394
Full Name	oligodendrocyte transcription factor 1
Synonyms	Olg1,oligo1
General protein information	Preferred Names oligodendrocyte transcription factor 1 Names oligodendrocyte transcription factor 1 Olg-1 bHLH protein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 11 Map Location: 11q11
Summary	This gene is a member of the oligodendrocyte lineage gene family which encode basic helix-loop-helix transcription factors. Studies in mice show that it is coexpressed with Olig2 in neural progenitors, and has a role in the development and maturation of oligodendrocytes. [provided by RefSeq, Jul 2008].

mRNA and Protein(s)

mRNA	Protein	Name
NM_021770.4	NP_068538.2	oligodendrocyte transcription factor 1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	OLIG1	NP_001193690.1
	LOC706574	XP_002803209.1
Pan troglodytes (chimpanzee)	OLIG1	XP_530336.2
Canis lupus familiaris (dog)	OLIG1	XP_852212.3
Danio rerio (zebrafish)	olig1	NP_001018632.1
Mus musculus (house mouse)	Olig1	NP_058664.2
Xenopus tropicalis (tropical clawed frog)	olig1	XP_004912200.1
Homo sapiens (human)	OLIG1	NP_620450.2
Rattus norvegicus (Norway rat)	Olig1	NP_068538.2

Gene Ontology
Bibliography

Related articles in PubMed

Antipsychotics promote the differentiation of oligodendrocyte progenitor cells by regulating oligodendrocyte lineage transcription factors 1 and 2.
Fang F, Zhang H, Zhang Y, Xu H, Huang Q, Adilijiang A, Wang J, Zhang Z, Zhang D, Tan Q, He J, Kong L, Liu Y, Li XM
Life sciences93(12-14)429-34(2013 Oct)

Olig1 and ID4 interactions in living cells visualized by bimolecular fluorescence complementation technique.
Guo SJ, Hu JG, Zhao BM, Shen L, Wang R, Zhou JS, L? HZ
Molecular biology reports38(7)4637-42(2011 Oct)

Bone morphogenetic protein signaling and olig1/2 interact to regulate the differentiation and maturation of adult oligodendrocyte precursor cells.
Cheng X, Wang Y, He Q, Qiu M, Whittemore SR, Cao Q
Stem cells (Dayton, Ohio)25(12)3204-14(2007 Dec)

Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection.
Lu QR, Sun T, Zhu Z, Ma N, Garcia M, Stiles CD, Rowitch DH
Cell109(1)75-86(2002 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Olig1 and Olig2 expression are enhanced during antipsychotic drug induced differentiation of oligodendrocyte progenitor cells.
Title: Antipsychotics promote the differentiation of oligodendrocyte progenitor cells by regulating oligodendrocyte lineage transcription factors 1 and 2.

Bimolecular fluorescence complementation (BiFC) analysis was performed to further characterize the distinct subcellular localization of olig1, ID4 and their dimer.
Title: Olig1 and ID4 interactions in living cells visualized by bimolecular fluorescence complementation technique.

Overexpression of olig1 and olig2 inhibits astrocyte differentiation and promotes oligodendrocyte differentiation of adult oligodendrocyte precursor cells.
Title: Bone morphogenetic protein signaling and olig1/2 interact to regulate the differentiation and maturation of adult oligodendrocyte precursor cells.

The following Olig1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Olig1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa42761	NM_021770.4 Latest version!	Rattus norvegicus oligodendrocyte transcription factor 1 (Olig1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$188.30 $269.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Olig1 ( NM_021770.4 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_068538.2 Rattus norvegicus oligodendrocyte transcription factor 1 (Olig1), mRNA.

Price & Availability↑

CloneID	ORa42761
Clone ID Related Accession (Same CDS sequence)	NM_021770.4
Accession Version	NM_021770.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 786bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-25
Organism	Rattus norvegicus(Norway rat)
Product	oligodendrocyte transcription factor 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC112633.6. On Jan 9, 2017 this sequence version replaced NM_021770.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. COMPLETENESS: complete on the 3' end.

ATGTACTATG CGGTTTCCCA GGCGCGTGTG AACGCGGCTC CCGCGACCAT GTTGCGGCCA 
CAGCGGCCCG GAGATGTGCA GCTCGGGGCT TCGTTGTACG AGCTGGTGGG TTACAGGCAG 
CCACCCATCT CGTCATCCTC CTCCACCTCC TCCTCCTCTA CCGCGTCCCT TCTCCCTAAA 
CCTGCGCGTG AGAAGCCTGA AGCTCCGCTC GCTGAGCCTC GGGGACCAGC GCCGGAGTCC 
GGGGGCGCCC GGGCCGACGC CAAAGAGGAG CAGCAGCAGC AGCAGCTGAG GCGCAAGATC 
AACAGCCGCG AGCGGAAGCG CATGCAGGAC CTGAACTTGG CCATGGACGC GCTGCGCGAA 
GTTATCCTAC CCTACTCCGC GGCGCACTGC CAGGGCGCGC CGGGCCGTAA GCTCTCCAAG 
ATCGCTACGC TGCTGCTCGC CCGCAACTAC ATCCTGCTGC TGGGCAGCTC TCTGCAGGAG 
CTGCGCCGCG CGCTCGGCGA CGGTGCGGGA CCCGCCGCCC CGCGCCTGCT CCTTGCGGGC 
CTGCCCCTGC TGGCCGCCGC GCCGGGCTCT GTGCTGCTGG CACCGGGCGC CGTGGGACCC 
CCCGAAACGC TGCGCCCCAC CAAGTACCTG TCTCTAGCGC TCGACGAGCC ACCGTGCGGC 
CAGTTCGCTC TCCCCGCTGG TGGCGCGGGT AGCCCCGGCC TCTGCTCCTG TGCGGTGTGC 
AAGTTCCCGC ATCTGGTCCC CGCCGGCCTG GGCTTGGCAG CGGTGCAGGC TCAGTTCTCC 
AAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_068538.2
CDS	94..879
Translation	MYYAVSQARVNAAPATMLRPQRPGDVQLGASLYELVGYRQPPISSSSSTSSSSTASLLPKPAREKPEAPLAEPRGPAPESGGARADAKEEQQQQQLRRKINSRERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLARNYILLLGSSLQELRRALGDGAGPAAPRLLLAGLPLLAAAPGSVLLAPGAVGPPETLRPTKYLSLALDEPPCGQFALPAGGAGSPGLCSCAVCKFPHLVPAGLGLAAVQAQFSK

Target ORF information:

RefSeq Version	NM_021770.4
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus oligodendrocyte transcription factor 1 (Olig1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021770.4

ORF Insert Sequence:

ATGTACTATG CGGTTTCCCA GGCGCGTGTG AACGCGGCTC CCGCGACCAT GTTGCGGCCA 
CAGCGGCCCG GAGATGTGCA GCTCGGGGCT TCGTTGTACG AGCTGGTGGG TTACAGGCAG 
CCACCCATCT CGTCATCCTC CTCCACCTCC TCCTCCTCTA CCGCGTCCCT TCTCCCTAAA 
CCTGCGCGTG AGAAGCCTGA AGCTCCGCTC GCTGAGCCTC GGGGACCAGC GCCGGAGTCC 
GGGGGCGCCC GGGCCGACGC CAAAGAGGAG CAGCAGCAGC AGCAGCTGAG GCGCAAGATC 
AACAGCCGCG AGCGGAAGCG CATGCAGGAC CTGAACTTGG CCATGGACGC GCTGCGCGAA 
GTTATCCTAC CCTACTCCGC GGCGCACTGC CAGGGCGCGC CGGGCCGTAA GCTCTCCAAG 
ATCGCTACGC TGCTGCTCGC CCGCAACTAC ATCCTGCTGC TGGGCAGCTC TCTGCAGGAG 
CTGCGCCGCG CGCTCGGCGA CGGTGCGGGA CCCGCCGCCC CGCGCCTGCT CCTTGCGGGC 
CTGCCCCTGC TGGCCGCCGC GCCGGGCTCT GTGCTGCTGG CACCGGGCGC CGTGGGACCC 
CCCGAAACGC TGCGCCCCAC CAAGTACCTG TCTCTAGCGC TCGACGAGCC ACCGTGCGGC 
CAGTTCGCTC TCCCCGCTGG TGGCGCGGGT AGCCCCGGCC TCTGCTCCTG TGCGGTGTGC 
AAGTTCCCGC ATCTGGTCCC CGCCGGCCTG GGCTTGGCAG CGGTGCAGGC TCAGTTCTCC 
AAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Antipsychotics promote the differentiation of oligodendrocyte progenitor cells by regulating oligodendrocyte lineage transcription factors 1 and 2.
Life sciences93(12-14)429-34(2013 Oct)
Fang F,Zhang H,Zhang Y,Xu H,Huang Q,Adilijiang A,Wang J,Zhang Z,Zhang D,Tan Q,He J,Kong L,Liu Y,Li XM

Olig1 and ID4 interactions in living cells visualized by bimolecular fluorescence complementation technique.
Molecular biology reports38(7)4637-42(2011 Oct)
Guo SJ,Hu JG,Zhao BM,Shen L,Wang R,Zhou JS,L? HZ

Bone morphogenetic protein signaling and olig1/2 interact to regulate the differentiation and maturation of adult oligodendrocyte precursor cells.
Stem cells (Dayton, Ohio)25(12)3204-14(2007 Dec)
Cheng X,Wang Y,He Q,Qiu M,Whittemore SR,Cao Q

Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection.
Cell109(1)75-86(2002 Apr)
Lu QR,Sun T,Zhu Z,Ma N,Garcia M,Stiles CD,Rowitch DH

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Olig1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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