Lmna cDNA ORF clone, Rattus norvegicus(Norway rat)

Lamin A/C mutation associated with lipodystrophy influences adipogenic differentiation of stem cells through interaction with Notch signaling.
Perepelina K, Dmitrieva RI, Ignatieva E, Borodkina A, Kostareva A, Malashicheva A
Biochemistry and cell biology = Biochimie et biologie cellulaire(2017 Oct)

The effect of the lamin A and its mutants on nuclear structure, cell proliferation, protein stability, and mobility in embryonic cells.
Piekarowicz K, Machowska M, Dratkiewicz E, Lorek D, Madej-Pilarczyk A, Rzepecki R
Chromosoma126(4)501-517(2017 Aug)

Nuclear envelope proteins modulate proliferation of vascular smooth muscle cells during cyclic stretch application.
Qi YX, Yao QP, Huang K, Shi Q, Zhang P, Wang GL, Han Y, Bao H, Wang L, Li HP, Shen BR, Wang Y, Chien S, Jiang ZL
Proceedings of the National Academy of Sciences of the United States of America113(19)5293-8(2016 May)

Lamin A is involved in the development of vascular calcification induced by chronic kidney failure and phosphorus load.
Quir?s-Gonz?lez I, Rom?n-Garc?a P, Alonso-Montes C, Barrio-V?zquez S, Carrillo-L?pez N, Naves-D?az M, Mora MI, Corrales FJ, L?pez-Hern?ndez FJ, Ruiz-Torres MP, Cannata-And?a JB, Fern?ndez-Mart?n JL
Bone84160-8(2016 Mar)

CDK4 is an essential insulin effector in adipocytes.
Lagarrigue S, Lopez-Mejia IC, Denechaud PD, Escot? X, Castillo-Armengol J, Jimenez V, Chavey C, Giralt A, Lai Q, Zhang L, Martinez-Carreres L, Delacuisine B, Annicotte JS, Blanchet E, Hur? S, Abella A, Tinahones FJ, Vendrell J, Dubus P, Bosch F, Kahn CR, Fajas L
The Journal of clinical investigation126(1)335-48(2016 Jan)

Our findings establish the pathogenetic role of emerin and lamin A/C repression in stretch-induced VSMC proliferation and suggest mechanobiological mechanism underlying this process that involves the sequence-specific binding of emerin and lamin A/C to specific transcription factor motifs.
Title: Nuclear envelope proteins modulate proliferation of vascular smooth muscle cells during cyclic stretch application.

the knockdown of prelamin A and lamin A inhibited the increase of Runx2, osteocalcin and osteopontin gene expression, calcium deposition, nuclear abnormalities and the RUNX2 protein translocation into the nucleus of the cell.
Title: Lamin A is involved in the development of vascular calcification induced by chronic kidney failure and phosphorus load.

Low shear strength suppresses the expression of Nesprin2 and LaminA, which may subsequently modulate the activation of important transcription factors and eventually lead to endothelial cell dysfunction.
Title: Nuclear envelope proteins Nesprin2 and LaminA regulate proliferation and apoptosis of vascular endothelial cells in response to shear stress.

This differential expression pattern of lamin a in retinal neurons suggests that they may be involved in cellular differentiation and expression of cell-specific genes in individual retinal neurons.
Title: Nuclear lamins are differentially expressed in retinal neurons of the adult rat retina.

Posttranslational arginine methylation of lamin A/C during myoblast fusion.
Title: Posttranslational arginine methylation of lamin A/C during myoblast fusion.