Parva cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Parva
Entrez Gene ID	57341
Full Name	parvin, alpha
Synonyms	Actp
General protein information	Preferred Names parvin, alpha Names alpha-parvin actopaxin
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q33
Summary	may regulate reorganization of the actin cytoskeleton in cell division [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_020656.2	NP_065707.2	alpha-parvin
XM_017589619.1	XP_017445108.1	alpha-parvin isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	PARVA	NP_060692.2
Mus musculus (house mouse)	Parva	NP_065631.3
Rattus norvegicus (Norway rat)	Parva	NP_065707.2
Caenorhabditis elegans (roundworm)	pat-6	NP_499891.1
Danio rerio (zebrafish)	parvaa	NP_001002872.1
Xenopus tropicalis (tropical clawed frog)	parva	XP_004913392.1
Canis lupus familiaris (dog)	PARVA	XP_005633732.1
Gallus gallus (chicken)	PARVA	XP_004941418.1
Pan troglodytes (chimpanzee)	PARVA	XP_001171467.3
	PARVA	XP_001091788.2
Bos taurus (cattle)	PARVA	XP_003587004.2

Gene Ontology
Bibliography

Related articles in PubMed

The WD40-domain containing protein CORO2B is specifically enriched in glomerular podocytes and regulates the ventral actin cytoskeleton.
Rogg M, Yasuda-Yamahara M, Abed A, Dinse P, Helmst?dter M, Conzelmann AC, Frimmel J, Sellung D, Biniossek ML, Kretz O, Grahammer F, Schilling O, Huber TB, Schell C
Scientific reports7(1)15910(2017 Nov)

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.
Guo Z, Neilson LJ, Zhong H, Murray PS, Zanivan S, Zaidel-Bar R
Science signaling7(354)rs7(2014 Dec)

Mutations in the paxillin-binding site of integrin-linked kinase (ILK) destabilize the pseudokinase domain and cause embryonic lethality in mice.
Moik D, B?ttcher A, Makhina T, Grashoff C, Bulus N, Zent R, F?ssler R
The Journal of biological chemistry288(26)18863-71(2013 Jun)

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for ?-Pix in negative regulation of focal adhesion maturation.
Kuo JC, Han X, Hsiao CT, Yates JR 3rd, Waterman CM
Nature cell biology13(4)383-93(2011 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

TGF-beta1-induced alteration of the PIP complex formation may be importantly implicated in the development and progression of glomerular failure shown in several kidney diseases
Title: TGF-beta1-induced PINCH-1-ILK-alpha-parvin complex formation regulates mesangial cell proliferation and hypertrophy.

Actopaxin is phosphorylated during mitosis and is a substrate for cyclin B1/cdc2 kinase.
Title: Actopaxin is phosphorylated during mitosis and is a substrate for cyclin B1/cdc2 kinase.

The following Parva gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Parva cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa04819	NM_020656.2 Latest version!	Rattus norvegicus parvin, alpha (Parva), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa56801	XM_017589619.1 Latest version!	Rattus norvegicus parvin, alpha (Parva), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Parva ( NM_020656.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_065707.2 Rattus norvegicus parvin, alpha (Parva), mRNA.

Price & Availability↑

CloneID	ORa04819
Clone ID Related Accession (Same CDS sequence)	NM_020656.2
Accession Version	NM_020656.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1119bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Rattus norvegicus(Norway rat)
Product	alpha-parvin
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF264765.2. On Apr 10, 2001 this sequence version replaced NM_020656.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF264765.2, FQ228521.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGCCACAT CCCCACAGAA GTCACCCTCG GTCCCCAAAT CTCCCACCCC CAAGTCGCCT 
CCGTCCCGCA AGAAGGATGA CTCGTTCTTG GGGAAACTTG GAGGGACGCT GGCCCGGAGG 
AAGAAAGCCA AGGAAGTATC CGAGTTCCAG GAGGAAGGAA TGAACGCCAT CAACCTGCCT 
CTTAGCCCCA TCTCCTTCGA GCTGGACCCC GAAGACACCA TGCTGGAGGA GAATGAGGTG 
CGGACAATGG TCGATCCAAA CTCACGCAAT GACCCCAAGC TTCAAGAGCT GATGAAGGTG 
CTCATCGACT GGATCAATGA CGTATTGGTG GGAGAAAGAA TCATCGTGAA GGACCTCGCT 
GAAGATCTCT ATGATGGCCA AGTCCTGCAG AAGCTCTTCG AGAAACTGGA GAGTGAGAAG 
CTCAACGTGG CAGAGGTTAC CCAGTCGGAG ATCGCCCAGA AGCAAAAGCT ACAGACTGTA 
CTGGAGAAGA TCAACGAGGC CCTGAAGCTT CCTCCCAGGA GCATCAAGTG GAACGTAGAC 
TCTGTTCATG CCAAGAACCT GGTTGCCATC CTCCACCTGC TGGTTGCCCT GTCTCAGTAT 
TTCCGGGCAC CAATCCGACT CCCAGACCAT GTTTCCATCC AAGTGGTTGT GGTCCAGAAA 
CGGGAAGGGA TCCTTCAGTC TCGGCAAATC CAAGAGGAAA TAACTGGTAA CACAGAGGCC 
CTTTCCGGAA GGCATGAACG CGATGCCTTT GACACGCTGT TTGACCATGC ACCAGACAAA 
CTCAATGTGG TGAAGAAGAC CCTCATCACG TTCGTGAACA AGCACCTGAA TAAACTGAAC 
TTGGAGGTCA CAGAACTGGA GACGCAGTTT GCAGATGGGG TCTACCTGGT GCTGCTCATG 
GGGCTCCTGG AGGGCTACTT TGTACCCCTG CACAGCTTCT TCCTGACCCC AGACAGCTTT 
GAACAGAAGG TCCTGAATGT TTCCTTTGCC TTTGAACTCA TGCAAGATGG AGGGCTGGAA 
AAGCCTAAAC CTCGGCCAGA AGACATTGTC AACTGTGACC TGAAGTCCAC GCTGAGAGTG 
CTGTACAACC TCTTCACCAA GTACCGGAAT GTGGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_065707.2
CDS	1..1119
Translation	MATSPQKSPSVPKSPTPKSPPSRKKDDSFLGKLGGTLARRKKAKEVSEFQEEGMNAINLPLSPISFELDPEDTMLEENEVRTMVDPNSRNDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINEALKLPPRSIKWNVDSVHAKNLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEALSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYRNVE

Target ORF information:

RefSeq Version	NM_020656.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus parvin, alpha (Parva), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020656.2

ORF Insert Sequence:

ATGGCCACAT CCCCACAGAA GTCACCCTCG GTCCCCAAAT CTCCCACCCC CAAGTCGCCT 
CCGTCCCGCA AGAAGGATGA CTCGTTCTTG GGGAAACTTG GAGGGACGCT GGCCCGGAGG 
AAGAAAGCCA AGGAAGTATC CGAGTTCCAG GAGGAAGGAA TGAACGCCAT CAACCTGCCT 
CTTAGCCCCA TCTCCTTCGA GCTGGACCCC GAAGACACCA TGCTGGAGGA GAATGAGGTG 
CGGACAATGG TCGATCCAAA CTCACGCAAT GACCCCAAGC TTCAAGAGCT GATGAAGGTG 
CTCATCGACT GGATCAATGA CGTATTGGTG GGAGAAAGAA TCATCGTGAA GGACCTCGCT 
GAAGATCTCT ATGATGGCCA AGTCCTGCAG AAGCTCTTCG AGAAACTGGA GAGTGAGAAG 
CTCAACGTGG CAGAGGTTAC CCAGTCGGAG ATCGCCCAGA AGCAAAAGCT ACAGACTGTA 
CTGGAGAAGA TCAACGAGGC CCTGAAGCTT CCTCCCAGGA GCATCAAGTG GAACGTAGAC 
TCTGTTCATG CCAAGAACCT GGTTGCCATC CTCCACCTGC TGGTTGCCCT GTCTCAGTAT 
TTCCGGGCAC CAATCCGACT CCCAGACCAT GTTTCCATCC AAGTGGTTGT GGTCCAGAAA 
CGGGAAGGGA TCCTTCAGTC TCGGCAAATC CAAGAGGAAA TAACTGGTAA CACAGAGGCC 
CTTTCCGGAA GGCATGAACG CGATGCCTTT GACACGCTGT TTGACCATGC ACCAGACAAA 
CTCAATGTGG TGAAGAAGAC CCTCATCACG TTCGTGAACA AGCACCTGAA TAAACTGAAC 
TTGGAGGTCA CAGAACTGGA GACGCAGTTT GCAGATGGGG TCTACCTGGT GCTGCTCATG 
GGGCTCCTGG AGGGCTACTT TGTACCCCTG CACAGCTTCT TCCTGACCCC AGACAGCTTT 
GAACAGAAGG TCCTGAATGT TTCCTTTGCC TTTGAACTCA TGCAAGATGG AGGGCTGGAA 
AAGCCTAAAC CTCGGCCAGA AGACATTGTC AACTGTGACC TGAAGTCCAC GCTGAGAGTG 
CTGTACAACC TCTTCACCAA GTACCGGAAT GTGGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Parva ( XM_017589619.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017445108.1 Rattus norvegicus parvin, alpha (Parva), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa56801
Clone ID Related Accession (Same CDS sequence)	XM_017589619.1
Accession Version	XM_017589619.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1011bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	alpha-parvin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCTGCG GGGCACTTTG CCCTAAAGTA TCCGAGTTCC AGGAGGAAGG AATGAACGCC 
ATCAACCTGC CTCTTAGCCC CATCTCCTTC GAGCTGGACC CCGAAGACAC CATGCTGGAG 
GAGAATGAGG TGCGGACAAT GGTCGATCCA AACTCACGCA ATGACCCCAA GCTTCAAGAG 
CTGATGAAGG TGCTCATCGA CTGGATCAAT GACGTATTGG TGGGAGAAAG AATCATCGTG 
AAGGACCTCG CTGAAGATCT CTATGATGGC CAAGTCCTGC AGAAGCTCTT CGAGAAACTG 
GAGAGTGAGA AGCTCAACGT GGCAGAGGTT ACCCAGTCGG AGATCGCCCA GAAGCAAAAG 
CTACAGACTG TACTGGAGAA GATCAACGAG ACCCTGAAGC TTCCTCCCAG GAGCATCAAG 
TGGAACGTAG ACTCTGTTCA TGCCAAGAAC CTGGTTGCCA TCCTCCACCT GCTGGTTGCC 
CTGTCTCAGT ATTTCCGGGC ACCAATCCGA CTCCCAGACC ATGTTTCCAT CCAAGTGGTT 
GTGGTCCAGA AACGGGAAGG GATCCTTCAG TCTCGGCAAA TCCAAGAGGA AATAACTGGT 
AACACAGAGG CCCTTTCCGG AAGGCATGAA CGCGATGCCT TTGACACACT GTTTGACCAT 
GCACCAGACA AACTCAATGT GGTGAAGAAG ACCCTCATCA CGTTCGTGAA CAAGCACCTG 
AATAAACTGA ACTTGGAGGT CACAGAACTG GAGACGCAGT TTGCAGATGG GGTCTACCTG 
GTGCTGCTCA TGGGGCTCCT GGAGGGCTAC TTTGTACCCC TGCACAGCTT CTTCCTGACC 
CCAGACAGCT TTGAACAGAA GGTCCTGAAT GTTTCCTTTG CCTTTGAACT CATGCAAGAT 
GGAGGGCTGG AAAAGCCTAA ACCTCGGCCA GAAGACATTG TCAACTGTGA CCTGAAGTCC 
ACGCTGAGAG TGCTGTACAA CCTCTTCACC AAGTACCGGA ATGTGGAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017445108.1
CDS	2497..3507
Translation	MGCGALCPKVSEFQEEGMNAINLPLSPISFELDPEDTMLEENEVRTMVDPNSRNDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVDSVHAKNLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEALSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYRNVE

Target ORF information:

RefSeq Version	XM_017589619.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus parvin, alpha (Parva), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017589619.1

ORF Insert Sequence:

ATGGGCTGCG GGGCACTTTG CCCTAAAGTA TCCGAGTTCC AGGAGGAAGG AATGAACGCC 
ATCAACCTGC CTCTTAGCCC CATCTCCTTC GAGCTGGACC CCGAAGACAC CATGCTGGAG 
GAGAATGAGG TGCGGACAAT GGTCGATCCA AACTCACGCA ATGACCCCAA GCTTCAAGAG 
CTGATGAAGG TGCTCATCGA CTGGATCAAT GACGTATTGG TGGGAGAAAG AATCATCGTG 
AAGGACCTCG CTGAAGATCT CTATGATGGC CAAGTCCTGC AGAAGCTCTT CGAGAAACTG 
GAGAGTGAGA AGCTCAACGT GGCAGAGGTT ACCCAGTCGG AGATCGCCCA GAAGCAAAAG 
CTACAGACTG TACTGGAGAA GATCAACGAG ACCCTGAAGC TTCCTCCCAG GAGCATCAAG 
TGGAACGTAG ACTCTGTTCA TGCCAAGAAC CTGGTTGCCA TCCTCCACCT GCTGGTTGCC 
CTGTCTCAGT ATTTCCGGGC ACCAATCCGA CTCCCAGACC ATGTTTCCAT CCAAGTGGTT 
GTGGTCCAGA AACGGGAAGG GATCCTTCAG TCTCGGCAAA TCCAAGAGGA AATAACTGGT 
AACACAGAGG CCCTTTCCGG AAGGCATGAA CGCGATGCCT TTGACACACT GTTTGACCAT 
GCACCAGACA AACTCAATGT GGTGAAGAAG ACCCTCATCA CGTTCGTGAA CAAGCACCTG 
AATAAACTGA ACTTGGAGGT CACAGAACTG GAGACGCAGT TTGCAGATGG GGTCTACCTG 
GTGCTGCTCA TGGGGCTCCT GGAGGGCTAC TTTGTACCCC TGCACAGCTT CTTCCTGACC 
CCAGACAGCT TTGAACAGAA GGTCCTGAAT GTTTCCTTTG CCTTTGAACT CATGCAAGAT 
GGAGGGCTGG AAAAGCCTAA ACCTCGGCCA GAAGACATTG TCAACTGTGA CCTGAAGTCC 
ACGCTGAGAG TGCTGTACAA CCTCTTCACC AAGTACCGGA ATGTGGAGTG A