Cd86 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cd86
Entrez Gene ID	56822
Full Name	CD86 molecule
Synonyms	B7-2
General protein information	Preferred Names CD86 molecule Names T-lymphocyte activation antigen CD86 cd86 antigen membrane glycoprotein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 11 Map Location: 11q22
Summary	plays a role in T-cell activation and proliferation [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006248399.3	XP_006248461.1	T-lymphocyte activation antigen CD86 isoform X1
NM_020081.1	NP_064466.1	T-lymphocyte activation antigen CD86 precursor
XM_006248400.2	XP_006248462.1	T-lymphocyte activation antigen CD86 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	CD86	NP_787058.4
Bos taurus (cattle)	CD86	NP_001033106.1
Pan troglodytes (chimpanzee)	CD86	XP_526283.2
	CD86	NP_001036109.1
Rattus norvegicus (Norway rat)	Cd86	NP_064466.1
Gallus gallus (chicken)	CD86	NP_001032928.1
Canis lupus familiaris (dog)	CD86	NP_001003146.1
Mus musculus (house mouse)	Cd86	NP_062261.3

Gene Ontology
Bibliography

Related articles in PubMed

A Lower Proportion of Regulatory B Cells in Patients with Henoch-Schoenlein Purpura Nephritis.
Hu X, Tai J, Qu Z, Zhao S, Zhang L, Li M, Sun X, Jiang Y
PloS one11(3)e0152368(2016)

Polymorphisms in CD28, CTLA-4, CD80 and CD86 genes may influence the risk of multiple sclerosis and its age of onset.
Wagner M, Sobczy?ski M, Karabon L, Bili?ska M, Pokryszko-Dragan A, Pawlak-Adamska E, Cyrul M, Ku?nierczyk P, Jasek M
Journal of neuroimmunology28879-86(2015 Nov)

AID induces intraclonal diversity and genomic damage in CD86(+) chronic lymphocytic leukemia cells.
Huemer M, Rebhandl S, Zaborsky N, Gassner FJ, Hainzl S, Weiss L, Hebenstreit D, Greil R, Geisberger R
European journal of immunology44(12)3747-57(2014 Dec)

Small interfering RNA against CD86 during allergen challenge blocks experimental allergic asthma.
Asai-Tajiri Y, Matsumoto K, Fukuyama S, Kan-O K, Nakano T, Tonai K, Ohno T, Azuma M, Inoue H, Nakanishi Y
Respiratory research15132(2014 Oct)

Astrocyte galectin-9 potentiates microglial TNF secretion.
Steelman AJ, Li J
Journal of neuroinflammation11144(2014 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Chondrogenic differentiation may increase the immunogenicity of mesenchymal stem cells, leading to stimulation of dendritic cells and upregulation of B7 molecules may be partially responsible for this event.
Title: Chondrogenic differentiation alters the immunosuppressive property of bone marrow-derived mesenchymal stem cells, and the effect is partially due to the upregulated expression of B7 molecules.

Lumbar spinal expression of the co-stimulatory molecules CD86 and CD80 in a rat model of neuropathy results in intense CD86 microglial expression in lumbar spinal cord after injury but no expression of CD80.
Title: Presence of spinal B7.2 (CD86) but not B7.1 (CD80) co-stimulatory molecules following peripheral nerve injury: role of nondestructive immunity in neuropathic pain.

B7.1 and B7.2 are expressed in the eye at different times during experimental autoimmune anterior uveitis. Both B7 molecules are required for the induction of EAAU, although they probably have different roles.
Title: Expression of B7 molecules in the eye during experimental autoimmune anterior uveitis (EAAU).

The following Cd86 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cd86 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa04741	NM_020081.1 Latest version!	Rattus norvegicus CD86 molecule (Cd86), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa34311	XM_006248399.3 Latest version!	Rattus norvegicus CD86 molecule (Cd86), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa34311	XM_006248400.2 Latest version!	Rattus norvegicus CD86 molecule (Cd86), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cd86 ( NM_020081.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_064466.1 Rattus norvegicus CD86 molecule (Cd86), mRNA.

Price & Availability↑

CloneID	ORa04741
Clone ID Related Accession (Same CDS sequence)	NM_020081.1
Accession Version	NM_020081.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 942bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-08-03
Organism	Rattus norvegicus(Norway rat)
Product	T-lymphocyte activation antigen CD86 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from D50558.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: D50558.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689599, SAMEA2689603 [ECO:0000348] ##Evidence-Data-END##

ATGTATGTCG TCAAGACATG TGTAACCTGC ACCATGTACT TGGGAATCCT TTTCTCGGTG 
TTGGCCTATC TGCTCTCAGA TGCTGTTCCT GTGAAGAGGC AAGCTTACTT CAATAGCACT 
GCATACCTGC CGTGCCCGTT CACAAAGGCT CAAAACATAA GCCCGAGTGA GCTCGTAGTA 
TTTTGGCAGG ACCGGAAAAA GTCGGTTCTG TACGAACACT ATTTGGGCGC AGAGAAACTT 
GATAACGTGA ATGCCAAGTA CCTGGGCCGC ACAAGCTTTG ATAGGGATAA CCAGGCTCTA 
CGACTTCACA ATGTTCAGAT CAAGGACACG GGCTTGTATG ATTGTTTTAT ACAGCAAAAG 
ACACCCACGG GATCAATTAT CCTCCAGCAG TGGGAAACAG AGCTCTCAGT GATCGCCAAC 
TTCAGTGAAC CTGAAATAGA GGAGGCTCAG AATGAAACAA GAAACACTGG CATAAATTTG 
ACCTGCTCAT CTAAGCAAGG ATACCCGAAA CCTACAAAGA TGTATTTTTT GATAACTAAT 
TCAACTAATG AGTATGGCGA CAACATGCAG ATATCACAAG ACAATGTCAC AAAGCTGTTC 
AGTGTCTCCA TCAGCCTATC TCTTCCATTC CCGGATGGGG TGTACAATAT GACCATTGTG 
TGTATTCTGG AAACGGAGTC AATGAATATT TCCTCCAAAC CTCACAATAT GGTTTTTTCG 
CAGCCCCAGT TTGATCGAAA GACTTGGATC CAGATTGCAG GTCCCAGTTC ACTTCTGTGC 
TGTCTCTTTC TGCTGGTCGT CTACAAAGCA GTCAAAAAGT GTTTGAAGAT GCAGAACCAG 
CCCGGCAGAC CCAGCAGAAA GACTTGTGAG TCCAAGCAGG ACAGTGGTGT TGACGAGTCG 
ATCAACCTGG AGGAAGTTGA ACCCCAATTG CATCAGCAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_064466.1
CDS	1..942
Translation	MYVVKTCVTCTMYLGILFSVLAYLLSDAVPVKRQAYFNSTAYLPCPFTKAQNISPSELVVFWQDRKKSVLYEHYLGAEKLDNVNAKYLGRTSFDRDNQALRLHNVQIKDTGLYDCFIQQKTPTGSIILQQWETELSVIANFSEPEIEEAQNETRNTGINLTCSSKQGYPKPTKMYFLITNSTNEYGDNMQISQDNVTKLFSVSISLSLPFPDGVYNMTIVCILETESMNISSKPHNMVFSQPQFDRKTWIQIAGPSSLLCCLFLLVVYKAVKKCLKMQNQPGRPSRKTCESKQDSGVDESINLEEVEPQLHQQ

Target ORF information:

RefSeq Version	NM_020081.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus CD86 molecule (Cd86), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020081.1

ORF Insert Sequence:

ATGTATGTCG TCAAGACATG TGTAACCTGC ACCATGTACT TGGGAATCCT TTTCTCGGTG 
TTGGCCTATC TGCTCTCAGA TGCTGTTCCT GTGAAGAGGC AAGCTTACTT CAATAGCACT 
GCATACCTGC CGTGCCCGTT CACAAAGGCT CAAAACATAA GCCCGAGTGA GCTCGTAGTA 
TTTTGGCAGG ACCGGAAAAA GTCGGTTCTG TACGAACACT ATTTGGGCGC AGAGAAACTT 
GATAACGTGA ATGCCAAGTA CCTGGGCCGC ACAAGCTTTG ATAGGGATAA CCAGGCTCTA 
CGACTTCACA ATGTTCAGAT CAAGGACACG GGCTTGTATG ATTGTTTTAT ACAGCAAAAG 
ACACCCACGG GATCAATTAT CCTCCAGCAG TGGGAAACAG AGCTCTCAGT GATCGCCAAC 
TTCAGTGAAC CTGAAATAGA GGAGGCTCAG AATGAAACAA GAAACACTGG CATAAATTTG 
ACCTGCTCAT CTAAGCAAGG ATACCCGAAA CCTACAAAGA TGTATTTTTT GATAACTAAT 
TCAACTAATG AGTATGGCGA CAACATGCAG ATATCACAAG ACAATGTCAC AAAGCTGTTC 
AGTGTCTCCA TCAGCCTATC TCTTCCATTC CCGGATGGGG TGTACAATAT GACCATTGTG 
TGTATTCTGG AAACGGAGTC AATGAATATT TCCTCCAAAC CTCACAATAT GGTTTTTTCG 
CAGCCCCAGT TTGATCGAAA GACTTGGATC CAGATTGCAG GTCCCAGTTC ACTTCTGTGC 
TGTCTCTTTC TGCTGGTCGT CTACAAAGCA GTCAAAAAGT GTTTGAAGAT GCAGAACCAG 
CCCGGCAGAC CCAGCAGAAA GACTTGTGAG TCCAAGCAGG ACAGTGGTGT TGACGAGTCG 
ATCAACCTGG AGGAAGTTGA ACCCCAATTG CATCAGCAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cd86 ( XM_006248399.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006248461.1 Rattus norvegicus CD86 molecule (Cd86), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa34311
Clone ID Related Accession (Same CDS sequence)	XM_006248399.3 , XM_006248400.2
Accession Version	XM_006248399.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 909bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	T-lymphocyte activation antigen CD86 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005110.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006248399.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTACTTGG GAATCCTTTT CTCGGTGTTG GCCTATCTGC TCTCAGATGC TGTTCCTGTG 
AAGAGGCAAG CTTACTTCAA TAGCACTGCA TACCTGCCGT GCCCGTTCAC AAAGGCTCAA 
AACATAAGCC CGAGTGAGCT CGTAGTATTT TGGCAGGACC GGAAAAAGTC GGTTCTGTAC 
GAACACTATT TGGGCGCAGA GAAACTTGAT AACGTGAATG CCAAGTACCT GGGCCGCACA 
AGCTTTGATA GGGATAACCA GGCTCTACGA CTTCACAATG TTCAGATCAA GGACACGGGC 
TTGTATGATT GTTTTATACA GCAAAAGACA CCCACGGGAT CAATTATCCT CCAGCAGTGG 
GAAACAGAGC TCTCAGTGAT CGCCAACTTC AGTGAACCTG AAATAGAGGA GGCTCAGAAT 
GAAACAAGAA ACACTGGCAT AAATTTGACC TGCTCATCTA AGCAAGGATA CCCGAAACCT 
ACAAAGATGT ATTTTTTGAT AACTAATTCA ACTAATGAGT ATGGCGACAA CATGCAGATA 
TCACAAGACA ATGTCACAAA GCTGTTCAGT GTCTCCATCA GCCTATCTCT TCCATTCCCG 
GATGGGGTGT ACAATATGAC CATTGTGTGT ATTCTGGAAA CGGAGTCAAT GAATATTTCC 
TCCAAACCTC ACAATATGGT TTTTTCGCAG CCCCAGTTTG ATCGAAAGAC TTGGATCCAG 
ATTGCAGGTC CCAGTTCACT TCTGTGCTGT CTCTTTCTGC TGGTCGTCTA CAAAGCAGTC 
AAAAAGTGTT TGAAGATGCA GAACCAGCCC GGCAGACCCA GCAGAAAGAC TTGTGAGTCC 
AAGCAGGACA GTGGTGTTGA CGAGTCGATC AACCTGGAGG AAGTTGAACC CCAATTGCAT 
CAGCAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006248461.1
CDS	398..1306
Translation	MYLGILFSVLAYLLSDAVPVKRQAYFNSTAYLPCPFTKAQNISPSELVVFWQDRKKSVLYEHYLGAEKLDNVNAKYLGRTSFDRDNQALRLHNVQIKDTGLYDCFIQQKTPTGSIILQQWETELSVIANFSEPEIEEAQNETRNTGINLTCSSKQGYPKPTKMYFLITNSTNEYGDNMQISQDNVTKLFSVSISLSLPFPDGVYNMTIVCILETESMNISSKPHNMVFSQPQFDRKTWIQIAGPSSLLCCLFLLVVYKAVKKCLKMQNQPGRPSRKTCESKQDSGVDESINLEEVEPQLHQQ

Target ORF information:

RefSeq Version	XM_006248399.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus CD86 molecule (Cd86), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006248399.3

ORF Insert Sequence:

ATGTACTTGG GAATCCTTTT CTCGGTGTTG GCCTATCTGC TCTCAGATGC TGTTCCTGTG 
AAGAGGCAAG CTTACTTCAA TAGCACTGCA TACCTGCCGT GCCCGTTCAC AAAGGCTCAA 
AACATAAGCC CGAGTGAGCT CGTAGTATTT TGGCAGGACC GGAAAAAGTC GGTTCTGTAC 
GAACACTATT TGGGCGCAGA GAAACTTGAT AACGTGAATG CCAAGTACCT GGGCCGCACA 
AGCTTTGATA GGGATAACCA GGCTCTACGA CTTCACAATG TTCAGATCAA GGACACGGGC 
TTGTATGATT GTTTTATACA GCAAAAGACA CCCACGGGAT CAATTATCCT CCAGCAGTGG 
GAAACAGAGC TCTCAGTGAT CGCCAACTTC AGTGAACCTG AAATAGAGGA GGCTCAGAAT 
GAAACAAGAA ACACTGGCAT AAATTTGACC TGCTCATCTA AGCAAGGATA CCCGAAACCT 
ACAAAGATGT ATTTTTTGAT AACTAATTCA ACTAATGAGT ATGGCGACAA CATGCAGATA 
TCACAAGACA ATGTCACAAA GCTGTTCAGT GTCTCCATCA GCCTATCTCT TCCATTCCCG 
GATGGGGTGT ACAATATGAC CATTGTGTGT ATTCTGGAAA CGGAGTCAAT GAATATTTCC 
TCCAAACCTC ACAATATGGT TTTTTCGCAG CCCCAGTTTG ATCGAAAGAC TTGGATCCAG 
ATTGCAGGTC CCAGTTCACT TCTGTGCTGT CTCTTTCTGC TGGTCGTCTA CAAAGCAGTC 
AAAAAGTGTT TGAAGATGCA GAACCAGCCC GGCAGACCCA GCAGAAAGAC TTGTGAGTCC 
AAGCAGGACA GTGGTGTTGA CGAGTCGATC AACCTGGAGG AAGTTGAACC CCAATTGCAT 
CAGCAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cd86 ( XM_006248400.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006248462.1 Rattus norvegicus CD86 molecule (Cd86), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa34311
Clone ID Related Accession (Same CDS sequence)	XM_006248399.3 , XM_006248400.2
Accession Version	XM_006248400.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 909bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	T-lymphocyte activation antigen CD86 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005110.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006248400.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTACTTGG GAATCCTTTT CTCGGTGTTG GCCTATCTGC TCTCAGATGC TGTTCCTGTG 
AAGAGGCAAG CTTACTTCAA TAGCACTGCA TACCTGCCGT GCCCGTTCAC AAAGGCTCAA 
AACATAAGCC CGAGTGAGCT CGTAGTATTT TGGCAGGACC GGAAAAAGTC GGTTCTGTAC 
GAACACTATT TGGGCGCAGA GAAACTTGAT AACGTGAATG CCAAGTACCT GGGCCGCACA 
AGCTTTGATA GGGATAACCA GGCTCTACGA CTTCACAATG TTCAGATCAA GGACACGGGC 
TTGTATGATT GTTTTATACA GCAAAAGACA CCCACGGGAT CAATTATCCT CCAGCAGTGG 
GAAACAGAGC TCTCAGTGAT CGCCAACTTC AGTGAACCTG AAATAGAGGA GGCTCAGAAT 
GAAACAAGAA ACACTGGCAT AAATTTGACC TGCTCATCTA AGCAAGGATA CCCGAAACCT 
ACAAAGATGT ATTTTTTGAT AACTAATTCA ACTAATGAGT ATGGCGACAA CATGCAGATA 
TCACAAGACA ATGTCACAAA GCTGTTCAGT GTCTCCATCA GCCTATCTCT TCCATTCCCG 
GATGGGGTGT ACAATATGAC CATTGTGTGT ATTCTGGAAA CGGAGTCAAT GAATATTTCC 
TCCAAACCTC ACAATATGGT TTTTTCGCAG CCCCAGTTTG ATCGAAAGAC TTGGATCCAG 
ATTGCAGGTC CCAGTTCACT TCTGTGCTGT CTCTTTCTGC TGGTCGTCTA CAAAGCAGTC 
AAAAAGTGTT TGAAGATGCA GAACCAGCCC GGCAGACCCA GCAGAAAGAC TTGTGAGTCC 
AAGCAGGACA GTGGTGTTGA CGAGTCGATC AACCTGGAGG AAGTTGAACC CCAATTGCAT 
CAGCAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006248462.1
CDS	10..918
Translation	MYLGILFSVLAYLLSDAVPVKRQAYFNSTAYLPCPFTKAQNISPSELVVFWQDRKKSVLYEHYLGAEKLDNVNAKYLGRTSFDRDNQALRLHNVQIKDTGLYDCFIQQKTPTGSIILQQWETELSVIANFSEPEIEEAQNETRNTGINLTCSSKQGYPKPTKMYFLITNSTNEYGDNMQISQDNVTKLFSVSISLSLPFPDGVYNMTIVCILETESMNISSKPHNMVFSQPQFDRKTWIQIAGPSSLLCCLFLLVVYKAVKKCLKMQNQPGRPSRKTCESKQDSGVDESINLEEVEPQLHQQ

Target ORF information:

RefSeq Version	XM_006248400.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus CD86 molecule (Cd86), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006248400.2

ORF Insert Sequence:

ATGTACTTGG GAATCCTTTT CTCGGTGTTG GCCTATCTGC TCTCAGATGC TGTTCCTGTG 
AAGAGGCAAG CTTACTTCAA TAGCACTGCA TACCTGCCGT GCCCGTTCAC AAAGGCTCAA 
AACATAAGCC CGAGTGAGCT CGTAGTATTT TGGCAGGACC GGAAAAAGTC GGTTCTGTAC 
GAACACTATT TGGGCGCAGA GAAACTTGAT AACGTGAATG CCAAGTACCT GGGCCGCACA 
AGCTTTGATA GGGATAACCA GGCTCTACGA CTTCACAATG TTCAGATCAA GGACACGGGC 
TTGTATGATT GTTTTATACA GCAAAAGACA CCCACGGGAT CAATTATCCT CCAGCAGTGG 
GAAACAGAGC TCTCAGTGAT CGCCAACTTC AGTGAACCTG AAATAGAGGA GGCTCAGAAT 
GAAACAAGAA ACACTGGCAT AAATTTGACC TGCTCATCTA AGCAAGGATA CCCGAAACCT 
ACAAAGATGT ATTTTTTGAT AACTAATTCA ACTAATGAGT ATGGCGACAA CATGCAGATA 
TCACAAGACA ATGTCACAAA GCTGTTCAGT GTCTCCATCA GCCTATCTCT TCCATTCCCG 
GATGGGGTGT ACAATATGAC CATTGTGTGT ATTCTGGAAA CGGAGTCAAT GAATATTTCC 
TCCAAACCTC ACAATATGGT TTTTTCGCAG CCCCAGTTTG ATCGAAAGAC TTGGATCCAG 
ATTGCAGGTC CCAGTTCACT TCTGTGCTGT CTCTTTCTGC TGGTCGTCTA CAAAGCAGTC 
AAAAAGTGTT TGAAGATGCA GAACCAGCCC GGCAGACCCA GCAGAAAGAC TTGTGAGTCC 
AAGCAGGACA GTGGTGTTGA CGAGTCGATC AACCTGGAGG AAGTTGAACC CCAATTGCAT 
CAGCAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A Lower Proportion of Regulatory B Cells in Patients with Henoch-Schoenlein Purpura Nephritis.
PloS one11(3)e0152368(2016)
Hu X,Tai J,Qu Z,Zhao S,Zhang L,Li M,Sun X,Jiang Y

Polymorphisms in CD28, CTLA-4, CD80 and CD86 genes may influence the risk of multiple sclerosis and its age of onset.
Journal of neuroimmunology28879-86(2015 Nov)
Wagner M,Sobczy?ski M,Karabon L,Bili?ska M,Pokryszko-Dragan A,Pawlak-Adamska E,Cyrul M,Ku?nierczyk P,Jasek M

AID induces intraclonal diversity and genomic damage in CD86(+) chronic lymphocytic leukemia cells.
European journal of immunology44(12)3747-57(2014 Dec)
Huemer M,Rebhandl S,Zaborsky N,Gassner FJ,Hainzl S,Weiss L,Hebenstreit D,Greil R,Geisberger R

Small interfering RNA against CD86 during allergen challenge blocks experimental allergic asthma.
Respiratory research15132(2014 Oct)
Asai-Tajiri Y,Matsumoto K,Fukuyama S,Kan-O K,Nakano T,Tonai K,Ohno T,Azuma M,Inoue H,Nakanishi Y

Astrocyte galectin-9 potentiates microglial TNF secretion.
Journal of neuroinflammation11144(2014 Aug)
Steelman AJ,Li J

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Cd86 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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