Srcin1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Srcin1
Entrez Gene ID	56029
Full Name	SRC kinase signaling inhibitor 1
Synonyms	P140,Snip
General protein information	Preferred Names SRC kinase signaling inhibitor 1 Names SRC kinase signaling inhibitor 1 SNAP25-interacting protein p130Cas-associated protein p140Cap
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q31
Summary	SNAP-25-interacting protein; may be involved in exocytosis [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_019378.1	NP_062251.1	SRC kinase signaling inhibitor 1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SRCIN1	XP_003953102.1
Homo sapiens (human)	SRCIN1	NP_079524.2
	SNIP	XP_001082491.2
Canis lupus familiaris (dog)	SRCIN1	XP_005624645.1
Bos taurus (cattle)	SRCIN1	XP_002695994.3
Gallus gallus (chicken)	SRCIN1	XP_003643817.2
Rattus norvegicus (Norway rat)	Srcin1	NP_062251.1
Danio rerio (zebrafish)	LOC565863	XP_005164205.1
Mus musculus (house mouse)	Srcin1	NP_061361.2
Xenopus tropicalis (tropical clawed frog)	srcin1	NP_001121511.1

Gene Ontology
Bibliography

Related articles in PubMed

A Critical Role of Presynaptic Cadherin/Catenin/p140Cap Complexes in Stabilizing Spines and Functional Synapses in the Neocortex.
Li MY, Miao WY, Wu QZ, He SJ, Yan G, Yang Y, Liu JJ, Taketo MM, Yu X
Neuron94(6)1155-1172.e8(2017 Jun)

p140Cap regulates memory and synaptic plasticity through Src-mediated and citron-N-mediated actin reorganization.
Repetto D, Camera P, Melani R, Morello N, Russo I, Calcagno E, Tomasoni R, Bianchi F, Berto G, Giustetto M, Berardi N, Pizzorusso T, Matteoli M, Di Stefano P, Missler M, Turco E, Di Cunto F, Defilippi P
The Journal of neuroscience : the official journal of the Society for Neuroscience34(4)1542-53(2014 Jan)

Localization of multidomain adaptor proteins, p140Cap and vinexin, in the pancreatic islet of a spontaneous diabetes mellitus model, Otsuka Long-Evans Tokushima Fatty rats.
Yamauchi M, Sudo K, Ito H, Iwamoto I, Morishita R, Murai T, Kajita K, Ishizuka T, Nagata K
Medical molecular morphology46(1)41-8(2013 Mar)

p140Cap suppresses the invasive properties of highly metastatic MTLn3-EGFR cells via impaired cortactin phosphorylation.
Damiano L, Le D?v?dec SE, Di Stefano P, Repetto D, Lalai R, Truong H, Xiong JL, Danen EH, Yan K, Verbeek FJ, De Luca E, Attanasio F, Buccione R, Turco E, van de Water B, Defilippi P
Oncogene31(5)624-33(2012 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Study demonstrates a critical role of presynaptic cadherin/catenin/p140Cap cell adhesion complexes in stabilizing functional synapses and spines in the developing neocortex.
Title: A Critical Role of Presynaptic Cadherin/Catenin/p140Cap Complexes in Stabilizing Spines and Functional Synapses in the Neocortex.

we here demonstrate that p140Cap is a key element for both learning and synaptic plasticity
Title: p140Cap regulates memory and synaptic plasticity through Src-mediated and citron-N-mediated actin reorganization.

Possible involvement of p140Cap in insulin secretion; the reduction of p140Cap might be related to abnormal insulin secretion in diabetes mellitus.
Title: Localization of multidomain adaptor proteins, p140Cap and vinexin, in the pancreatic islet of a spontaneous diabetes mellitus model, Otsuka Long-Evans Tokushima Fatty rats.

Data show that p140Cap suppresses the invasive properties of highly metastatic breast carcinoma cells by inhibiting cortactin-dependent cell motility.
Title: p140Cap suppresses the invasive properties of highly metastatic MTLn3-EGFR cells via impaired cortactin phosphorylation.

These results suggest that p140Cap is involved in neurotransmitter release, synapse formation/maintenance, and signaling.
Title: Characterization of a multidomain adaptor protein, p140Cap, as part of a pre-synaptic complex.

The following Srcin1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Srcin1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa12342	NM_019378.1 Latest version!	Rattus norvegicus SRC kinase signaling inhibitor 1 (Srcin1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$881.30 $1259.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Srcin1 ( NM_019378.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_062251.1 Rattus norvegicus SRC kinase signaling inhibitor 1 (Srcin1), mRNA.

Price & Availability↑

CloneID	ORa12342
Clone ID Related Accession (Same CDS sequence)	NM_019378.1
Accession Version	NM_019378.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3594bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-15
Organism	Rattus norvegicus(Norway rat)
Product	SRC kinase signaling inhibitor 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF156982.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF156982.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGCAGCCCT GGCAGTGCCT CCGGCGCTTT GCCCTGGCCT GGTGGGAGAG GACCGCCGAG 
GGTCGCGCCC GTTCTCCCAG GGAGGAGGTT GGACCGAGGG ACCCTGGGGG CCGAGGGGAG 
CCAGATCCGG AGCGGAGCAG CCCCCCCATG CTGTCTGCCG ACGATGCCGA ATATCCTCGG 
GAGTACCGGA CCCTGGGGGG TGGGGGCAGC GGGGGCAGCG GGGGCCGGCG CTTCTCCAAC 
GTGGGGCTGG TGCACACCTC CGAGCGGCGG CACACGGTGA TCGCTGCCCA GAGCCTGGAG 
GCCCTCAGCG GGCTCCAGAA GGCCGATGCT GACCGCAAGC GAGATGCGTT TATGGACCAC 
CTGAAGAGCA AGTACCCCCA GCATGCCCTG GCCCTTCGAG GTCAGCAGGA CAGGATGAGA 
GAGCAGCAAC CAAACTACTG GAGTTTCAAG ACCCGCAGCT CGCGCCATAC TCAGGGAGCC 
CAGCCAGGGC TGGCAGACCA GGCAGCCAAG CTGTCCTACG CCTCGGCTGA GTCGCTGGAG 
ACAATGTCCG AGGCCGAGCT GCCCCTGGGC TTCAGCAGGA TGAATCGCTT CCGACAGAGC 
TTGCCTCTCT CCCGCTCTGC CAGCCAGACC AAGCTGCGCT CACCAGGAGT CCTGTTCCTG 
CAGTTCGGGG AGGAGACGCG ACGTGTACAC ATCACGCATG AGGTCAGCAG CCTGGACACG 
CTGCACGCAC TCATCGCGCA CATGTTCCCG CAGAAGCTCA CCATGGGCAT GCTTAAGTCG 
CCCAACACCG CCATCCTCAT CAAGGACGAG GCTCGCAACG TCTTCTACGA GCTGGAAGAC 
GTCCGGGATA TCCAGGACCG GAGTATCATC AAGATCTATA GGAAGGAGCC ACTGTATGCC 
GCTTTTCCTG GCTCGCACCT CACCAACGGT GACCTCCGGA GAGAGATGGT TTACGCATCG 
CGGGAGTCGT CGCCCACGCG GCGCCTCAAC AACCTGTCGC CCGCATCGCA CCTAGCATCT 
AGCTCCCCGC CTCCAGGGCT GCCATCCGGG CTGCCTTCGG GACTGCCATC GGGCTCGCCC 
TCGCGTTCAC GCCTCTCGTA TGCTGGGGGC CGGCCGCCCT CTTACGCCGG CAGCCCGGTA 
CACCACGCGG CTGAGCGACT GGGAGGCGCC CCGACCAGCC AGGGCGTGAG CCCCAGCCCC 
AGCGCCATCC TGGAGCGGCG CGACGTGAAG CCAGATGAGG ATCTGGCGGG CAAGGCGGGC 
GGCATGGTGC TGGTGAAGGG CGAGGGCCTC TATGCCGATC CCTACGGGCT GCTGCACGAG 
GGCCGCTTGA GCCTGGCCGC CGCAGCAGGA GACCCGTTCG CATACCCGGG CGCGGGCGGC 
TTGTACAAGC GGGGTTCTGT GCGCTCGCTC AGCACCTACT CGGCCGCTGC GCTGCAGTCC 
GACCTGGAGG ACTCGCTGTA CAAGGCGGGC GCCGGCGGCC CGCTCTACGG AGACGGCTAT 
GGCTTCCGTC TGCCGCCTTC GTCCCCGCAG AAACTAGCCG ACGTCTCAGC GCCCTCCGGG 
GGACCTCCGC CACCGCACAG CCCCTACTCT GGGCCGCCCA GCCGCGGCTC GCCGGTGCGC 
CAGTCGTTCC GTAAAGATTC TGGTTCCTCG TCGGTCTTTG CTGAGAGTCC TGGAGGCAAA 
GCCCGCAGCA CCGGGGCTTC CACGGCCGGA GCACCACCTT CTGAACTCTT CCCTGGACCT 
GGAGAGCGCT CCCTCGTAGG GTTCGGGCCG CCGGTGCCAG CCAAGGACAC AGAGACCAGG 
GAGCGTATGG AGGCCATGGA GAAGCAGATT GCCAGCCTCA CTGGGCTAGT ACAGAGTGCT 
TTACTGCGAG GCTCGGAGCC GGAGACCCCA AGTGAGAAGA TTGAAGGCTC CAATGGAGCA 
GCCACCCCCT CAGCACCAGT GTGTGGGTCA GGCAGTAGGA GTAGCGGGGC CACTCCAGTG 
TCGGGCCCTC CCCCACCCGC GGTCAGCAGC ACCCCTGCAG GGCAGCCCAC TGCTGTCAGC 
CGGCTGCAAA TGCAGATGCA TCTGCGTGGC CTACAGAACA GCGCTAGCGA CCTGCGTGGC 
CAGCTTCAGC AGTTGCGGAA GCTCCAGCTC CAGAACCAGG AGTCGGTGCG CGCGCTGCTG 
AAGCGCACCG AGGCGGAGCT GAGCATGCGC GTGTCGGAGG CGGCGCGGCG GCAGGAGGAC 
CCGCTGCAGC GGCAGCGCAC CCTGGTGGAA GAGGAGCGTT TGCGTTACCT CAACGACGAG 
GAGCTCATTA CACAGCAGCT CAATGACCTG GAGAAGTCAG TGGAGAAGAT CCAGAGGGAT 
GTGGCCCATA ACCACCGGCT GGTGCCTGGT CCTGAGTTGG AAGAGAAGGC TCTGGTGCTG 
AAACAGCTTG GGGAGACGCT GACGGAACTC AAGGCTCATT TCCCAGGCCT GCAGAGTAAG 
ATGCGGGTAG TGCTGCGTGT AGAGGTGGAG GCAGTCAAGT TTCTGAAGGA GGAACCTCAA 
CGCCTCGACG GGCTTCTCAA GCGCTGCCGG GTGGTCACTG ACACGCTGGC CCAGATCCGA 
AGGCAAGTGG ATGAGGGTGT GTGGCCTCCC CCCAACAATC TCCTGAACCA GTCCCCCAAG 
AAGGTGGCAG CCGAAACAGA CTTCAGCAAA GGCCTGGATT TTGAGATACC ACCCCCGAGT 
CCTCCACTGA ATCTCCACGA GCTGAGCGGG CCTGCGGAAG GCACCCCGCT TACCCCAAAA 
AGCGGCAACC CTACCAAAGG CCTGGATGCT CCGAGCAAGA GAAACATGGA CAAAGCTGTG 
TCTGTCGAGG CTGCAGAGAG AGACTGGGAA GAGAAGCGGG CCGCCCTGAC CCAGTACAGC 
GCCAAGGACA TCAACCGGCT GCTGGAGGAA ACCCAAGCTG AGCTGCTCAA GGCTATCCCC 
GACCTGGACT GTGCCAGCAA GACCCACCCA GGCCCTACTC CCACTCCAGA CCACAAGCCC 
CCTAAGGCAC CCCATGGTCA GAAGGCTGCT CCCCGGACAG AGCCCAGTGG GAGAAGAGGA 
TCAGATGAGC TCACAGTGCC CCGATACCGC ACAGAGAAGC CCTCCAAGTC GCCCCCGCCA 
CCCCCTCCCC GCCGGAGCTT CCCTTCCTCG CACGGCCTGA CCACCACTCG CACCGGAGAA 
GTGGTGGTCA CCAGTAAGAA AGACTCAGTC TTCATCAAGA AGGCTGAATC TGAGGAGCTG 
GAGATCCAGA AGCCTCAGGT GAAGCTGCGT CGCGCTGTGT CTGAGGTGGT CCGCCCCGCG 
TCCACACCGC CCATTATGGC CTCGGCCATC AAGGATGAAG ACGATGAGGA ACGCATCATT 
GCTGAGCTGG AGAGTGGTGG TGGCAGTGTG CCACCCATGA AGGTGGTGAC TCCCGGAGCC 
TCTCGGCTGA AGGCGGCCCA GGGTCCAGCA GGCAGCCCTG ATAAAGGCAA ACACGGCAAG 
CAACGAACGG AATACATGAG GATCCAGGCC CAGCAGCAGG TGAGGGTGGG ATACCAGGCA 
CCCAGGCCCC TGGAGGGCTG TACACCAAGG CTCTGCTATA TGCCGCTGTC TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_062251.1
CDS	124..3717
Translation	MQPWQCLRRFALAWWERTAEGRARSPREEVGPRDPGGRGEPDPERSSPPMLSADDAEYPREYRTLGGGGSGGSGGRRFSNVGLVHTSERRHTVIAAQSLEALSGLQKADADRKRDAFMDHLKSKYPQHALALRGQQDRMREQQPNYWSFKTRSSRHTQGAQPGLADQAAKLSYASAESLETMSEAELPLGFSRMNRFRQSLPLSRSASQTKLRSPGVLFLQFGEETRRVHITHEVSSLDTLHALIAHMFPQKLTMGMLKSPNTAILIKDEARNVFYELEDVRDIQDRSIIKIYRKEPLYAAFPGSHLTNGDLRREMVYASRESSPTRRLNNLSPASHLASSSPPPGLPSGLPSGLPSGSPSRSRLSYAGGRPPSYAGSPVHHAAERLGGAPTSQGVSPSPSAILERRDVKPDEDLAGKAGGMVLVKGEGLYADPYGLLHEGRLSLAAAAGDPFAYPGAGGLYKRGSVRSLSTYSAAALQSDLEDSLYKAGAGGPLYGDGYGFRLPPSSPQKLADVSAPSGGPPPPHSPYSGPPSRGSPVRQSFRKDSGSSSVFAESPGGKARSTGASTAGAPPSELFPGPGERSLVGFGPPVPAKDTETRERMEAMEKQIASLTGLVQSALLRGSEPETPSEKIEGSNGAATPSAPVCGSGSRSSGATPVSGPPPPAVSSTPAGQPTAVSRLQMQMHLRGLQNSASDLRGQLQQLRKLQLQNQESVRALLKRTEAELSMRVSEAARRQEDPLQRQRTLVEEERLRYLNDEELITQQLNDLEKSVEKIQRDVAHNHRLVPGPELEEKALVLKQLGETLTELKAHFPGLQSKMRVVLRVEVEAVKFLKEEPQRLDGLLKRCRVVTDTLAQIRRQVDEGVWPPPNNLLNQSPKKVAAETDFSKGLDFEIPPPSPPLNLHELSGPAEGTPLTPKSGNPTKGLDAPSKRNMDKAVSVEAAERDWEEKRAALTQYSAKDINRLLEETQAELLKAIPDLDCASKTHPGPTPTPDHKPPKAPHGQKAAPRTEPSGRRGSDELTVPRYRTEKPSKSPPPPPPRRSFPSSHGLTTTRTGEVVVTSKKDSVFIKKAESEELEIQKPQVKLRRAVSEVVRPASTPPIMASAIKDEDDEERIIAELESGGGSVPPMKVVTPGASRLKAAQGPAGSPDKGKHGKQRTEYMRIQAQQQVRVGYQAPRPLEGCTPRLCYMPLS

Target ORF information:

RefSeq Version	NM_019378.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus SRC kinase signaling inhibitor 1 (Srcin1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019378.1

ORF Insert Sequence:

ATGCAGCCCT GGCAGTGCCT CCGGCGCTTT GCCCTGGCCT GGTGGGAGAG GACCGCCGAG 
GGTCGCGCCC GTTCTCCCAG GGAGGAGGTT GGACCGAGGG ACCCTGGGGG CCGAGGGGAG 
CCAGATCCGG AGCGGAGCAG CCCCCCCATG CTGTCTGCCG ACGATGCCGA ATATCCTCGG 
GAGTACCGGA CCCTGGGGGG TGGGGGCAGC GGGGGCAGCG GGGGCCGGCG CTTCTCCAAC 
GTGGGGCTGG TGCACACCTC CGAGCGGCGG CACACGGTGA TCGCTGCCCA GAGCCTGGAG 
GCCCTCAGCG GGCTCCAGAA GGCCGATGCT GACCGCAAGC GAGATGCGTT TATGGACCAC 
CTGAAGAGCA AGTACCCCCA GCATGCCCTG GCCCTTCGAG GTCAGCAGGA CAGGATGAGA 
GAGCAGCAAC CAAACTACTG GAGTTTCAAG ACCCGCAGCT CGCGCCATAC TCAGGGAGCC 
CAGCCAGGGC TGGCAGACCA GGCAGCCAAG CTGTCCTACG CCTCGGCTGA GTCGCTGGAG 
ACAATGTCCG AGGCCGAGCT GCCCCTGGGC TTCAGCAGGA TGAATCGCTT CCGACAGAGC 
TTGCCTCTCT CCCGCTCTGC CAGCCAGACC AAGCTGCGCT CACCAGGAGT CCTGTTCCTG 
CAGTTCGGGG AGGAGACGCG ACGTGTACAC ATCACGCATG AGGTCAGCAG CCTGGACACG 
CTGCACGCAC TCATCGCGCA CATGTTCCCG CAGAAGCTCA CCATGGGCAT GCTTAAGTCG 
CCCAACACCG CCATCCTCAT CAAGGACGAG GCTCGCAACG TCTTCTACGA GCTGGAAGAC 
GTCCGGGATA TCCAGGACCG GAGTATCATC AAGATCTATA GGAAGGAGCC ACTGTATGCC 
GCTTTTCCTG GCTCGCACCT CACCAACGGT GACCTCCGGA GAGAGATGGT TTACGCATCG 
CGGGAGTCGT CGCCCACGCG GCGCCTCAAC AACCTGTCGC CCGCATCGCA CCTAGCATCT 
AGCTCCCCGC CTCCAGGGCT GCCATCCGGG CTGCCTTCGG GACTGCCATC GGGCTCGCCC 
TCGCGTTCAC GCCTCTCGTA TGCTGGGGGC CGGCCGCCCT CTTACGCCGG CAGCCCGGTA 
CACCACGCGG CTGAGCGACT GGGAGGCGCC CCGACCAGCC AGGGCGTGAG CCCCAGCCCC 
AGCGCCATCC TGGAGCGGCG CGACGTGAAG CCAGATGAGG ATCTGGCGGG CAAGGCGGGC 
GGCATGGTGC TGGTGAAGGG CGAGGGCCTC TATGCCGATC CCTACGGGCT GCTGCACGAG 
GGCCGCTTGA GCCTGGCCGC CGCAGCAGGA GACCCGTTCG CATACCCGGG CGCGGGCGGC 
TTGTACAAGC GGGGTTCTGT GCGCTCGCTC AGCACCTACT CGGCCGCTGC GCTGCAGTCC 
GACCTGGAGG ACTCGCTGTA CAAGGCGGGC GCCGGCGGCC CGCTCTACGG AGACGGCTAT 
GGCTTCCGTC TGCCGCCTTC GTCCCCGCAG AAACTAGCCG ACGTCTCAGC GCCCTCCGGG 
GGACCTCCGC CACCGCACAG CCCCTACTCT GGGCCGCCCA GCCGCGGCTC GCCGGTGCGC 
CAGTCGTTCC GTAAAGATTC TGGTTCCTCG TCGGTCTTTG CTGAGAGTCC TGGAGGCAAA 
GCCCGCAGCA CCGGGGCTTC CACGGCCGGA GCACCACCTT CTGAACTCTT CCCTGGACCT 
GGAGAGCGCT CCCTCGTAGG GTTCGGGCCG CCGGTGCCAG CCAAGGACAC AGAGACCAGG 
GAGCGTATGG AGGCCATGGA GAAGCAGATT GCCAGCCTCA CTGGGCTAGT ACAGAGTGCT 
TTACTGCGAG GCTCGGAGCC GGAGACCCCA AGTGAGAAGA TTGAAGGCTC CAATGGAGCA 
GCCACCCCCT CAGCACCAGT GTGTGGGTCA GGCAGTAGGA GTAGCGGGGC CACTCCAGTG 
TCGGGCCCTC CCCCACCCGC GGTCAGCAGC ACCCCTGCAG GGCAGCCCAC TGCTGTCAGC 
CGGCTGCAAA TGCAGATGCA TCTGCGTGGC CTACAGAACA GCGCTAGCGA CCTGCGTGGC 
CAGCTTCAGC AGTTGCGGAA GCTCCAGCTC CAGAACCAGG AGTCGGTGCG CGCGCTGCTG 
AAGCGCACCG AGGCGGAGCT GAGCATGCGC GTGTCGGAGG CGGCGCGGCG GCAGGAGGAC 
CCGCTGCAGC GGCAGCGCAC CCTGGTGGAA GAGGAGCGTT TGCGTTACCT CAACGACGAG 
GAGCTCATTA CACAGCAGCT CAATGACCTG GAGAAGTCAG TGGAGAAGAT CCAGAGGGAT 
GTGGCCCATA ACCACCGGCT GGTGCCTGGT CCTGAGTTGG AAGAGAAGGC TCTGGTGCTG 
AAACAGCTTG GGGAGACGCT GACGGAACTC AAGGCTCATT TCCCAGGCCT GCAGAGTAAG 
ATGCGGGTAG TGCTGCGTGT AGAGGTGGAG GCAGTCAAGT TTCTGAAGGA GGAACCTCAA 
CGCCTCGACG GGCTTCTCAA GCGCTGCCGG GTGGTCACTG ACACGCTGGC CCAGATCCGA 
AGGCAAGTGG ATGAGGGTGT GTGGCCTCCC CCCAACAATC TCCTGAACCA GTCCCCCAAG 
AAGGTGGCAG CCGAAACAGA CTTCAGCAAA GGCCTGGATT TTGAGATACC ACCCCCGAGT 
CCTCCACTGA ATCTCCACGA GCTGAGCGGG CCTGCGGAAG GCACCCCGCT TACCCCAAAA 
AGCGGCAACC CTACCAAAGG CCTGGATGCT CCGAGCAAGA GAAACATGGA CAAAGCTGTG 
TCTGTCGAGG CTGCAGAGAG AGACTGGGAA GAGAAGCGGG CCGCCCTGAC CCAGTACAGC 
GCCAAGGACA TCAACCGGCT GCTGGAGGAA ACCCAAGCTG AGCTGCTCAA GGCTATCCCC 
GACCTGGACT GTGCCAGCAA GACCCACCCA GGCCCTACTC CCACTCCAGA CCACAAGCCC 
CCTAAGGCAC CCCATGGTCA GAAGGCTGCT CCCCGGACAG AGCCCAGTGG GAGAAGAGGA 
TCAGATGAGC TCACAGTGCC CCGATACCGC ACAGAGAAGC CCTCCAAGTC GCCCCCGCCA 
CCCCCTCCCC GCCGGAGCTT CCCTTCCTCG CACGGCCTGA CCACCACTCG CACCGGAGAA 
GTGGTGGTCA CCAGTAAGAA AGACTCAGTC TTCATCAAGA AGGCTGAATC TGAGGAGCTG 
GAGATCCAGA AGCCTCAGGT GAAGCTGCGT CGCGCTGTGT CTGAGGTGGT CCGCCCCGCG 
TCCACACCGC CCATTATGGC CTCGGCCATC AAGGATGAAG ACGATGAGGA ACGCATCATT 
GCTGAGCTGG AGAGTGGTGG TGGCAGTGTG CCACCCATGA AGGTGGTGAC TCCCGGAGCC 
TCTCGGCTGA AGGCGGCCCA GGGTCCAGCA GGCAGCCCTG ATAAAGGCAA ACACGGCAAG 
CAACGAACGG AATACATGAG GATCCAGGCC CAGCAGCAGG TGAGGGTGGG ATACCAGGCA 
CCCAGGCCCC TGGAGGGCTG TACACCAAGG CTCTGCTATA TGCCGCTGTC TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A Critical Role of Presynaptic Cadherin/Catenin/p140Cap Complexes in Stabilizing Spines and Functional Synapses in the Neocortex.
Neuron94(6)1155-1172.e8(2017 Jun)
Li MY,Miao WY,Wu QZ,He SJ,Yan G,Yang Y,Liu JJ,Taketo MM,Yu X

p140Cap regulates memory and synaptic plasticity through Src-mediated and citron-N-mediated actin reorganization.
The Journal of neuroscience : the official journal of the Society for Neuroscience34(4)1542-53(2014 Jan)
Repetto D,Camera P,Melani R,Morello N,Russo I,Calcagno E,Tomasoni R,Bianchi F,Berto G,Giustetto M,Berardi N,Pizzorusso T,Matteoli M,Di Stefano P,Missler M,Turco E,Di Cunto F,Defilippi P

Localization of multidomain adaptor proteins, p140Cap and vinexin, in the pancreatic islet of a spontaneous diabetes mellitus model, Otsuka Long-Evans Tokushima Fatty rats.
Medical molecular morphology46(1)41-8(2013 Mar)
Yamauchi M,Sudo K,Ito H,Iwamoto I,Morishita R,Murai T,Kajita K,Ishizuka T,Nagata K

p140Cap suppresses the invasive properties of highly metastatic MTLn3-EGFR cells via impaired cortactin phosphorylation.
Oncogene31(5)624-33(2012 Feb)
Damiano L,Le D?v?dec SE,Di Stefano P,Repetto D,Lalai R,Truong H,Xiong JL,Danen EH,Yan K,Verbeek FJ,De Luca E,Attanasio F,Buccione R,Turco E,van de Water B,Defilippi P

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Srcin1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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