Slc14a2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Slc14a2
Entrez Gene ID	54302
Full Name	solute carrier family 14 member 2
Synonyms	Slc14a2T,Slc14a2_v4,UrT1-C,UrT1-D,testSymbol
General protein information	Preferred Names solute carrier family 14 member 2 Names urea transporter 2 plasma membrane urea transporter solute carrier family 14 (urea transporter), member 2, variant 4 solute carrier family 14 (urea transporter), member 2T testName urea transport protein urea transporter UT-A2c urea transporter UT-A2d urea transporter, kidney
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 18 Map Location: 18q12.3
Summary	acts as an cAMP inducible urea transporter; may play a role in vasopressin regulated renal water absorption [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001110270.1	NP_001103740.1	urea transporter 2 isoform 3
NM_177962.3	NP_808877.2	urea transporter 2 isoform 2
NM_019347.2	NP_062220.2	urea transporter 2 isoform 1

Pathways from BioSystems

Homologies

	SLC14A2	XP_001084040.1
Bos taurus (cattle)	SLC14A2	NP_001137574.1
Mus musculus (house mouse)	Slc14a2	NP_997534.2
Danio rerio (zebrafish)	slc14a2	NP_001018355.1
Gallus gallus (chicken)	SLC14A2	XP_003642954.2
Homo sapiens (human)	SLC14A2	NP_009094.3
Pan troglodytes (chimpanzee)	SLC14A2	XP_003315927.1
Rattus norvegicus (Norway rat)	Slc14a2	NP_062220.2
Canis lupus familiaris (dog)	SLC14A2	XP_005622912.1

Gene Ontology
Bibliography

Related articles in PubMed

Identification of UT-A1- and AQP2-interacting proteins in rat inner medullary collecting duct.
Chou CL, Hwang G, Hageman DJ, Han L, Agrawal P, Pisitkun T, Knepper MA
American journal of physiology. Cell physiology314(1)C99-C117(2018 Jan)

Alternative channels for urea in the inner medulla of the rat kidney.
Nawata CM, Dantzler WH, Pannabecker TL
American journal of physiology. Renal physiology309(11)F916-24(2015 Dec)

Downregulation of urea transporter UT-A1 activity by 14-3-3 protein.
Feng X, Li Z, Du Y, Fu H, Klein JD, Cai H, Sands JM, Chen G
American journal of physiology. Renal physiology309(1)F71-8(2015 Jul)

Structure-activity analysis of thiourea analogs as inhibitors of UT-A and UT-B urea transporters.
Esteva-Font C, Phuan PW, Lee S, Su T, Anderson MO, Verkman AS
Biochimica et biophysica acta1848(5)1075-80(2015 May)

Vasopressin regulation of multisite phosphorylation of UT-A1 in the inner medullary collecting duct.
Hoban CA, Black LN, Ordas RJ, Gumina DL, Pulous FE, Sim JH, Sands JM, Blount MA
American journal of physiology. Renal physiology308(1)F49-55(2015 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data indicate that there are several alternative channels for urea in the rat inner medulla that could potentially contribute to the high urea permeabilities in thin limb segments.
Title: Alternative channels for urea in the inner medulla of the rat kidney.

Activation of cAMP/PKA increases 14-3-3gamma interactions with UT-A1 and stimulates MDM2-mediated UT-A1 ubiquitination and degradation, forming a novel regulatory mechanism of urea transport activity.
Title: Downregulation of urea transporter UT-A1 activity by 14-3-3 protein.

Report thiourea analogs as inhibitors of UT-A mediated urea transport.
Title: Structure-activity analysis of thiourea analogs as inhibitors of UT-A and UT-B urea transporters.

UT-A1 localized to the apical membrane in response to vasopressin was phosphorylated at Ser(486) and Ser(499).
Title: Vasopressin regulation of multisite phosphorylation of UT-A1 in the inner medullary collecting duct.

The highly stable expression of highly glycosylated UT-A3 on the cell membrane in kidney inner medulla suggests that UT-A3 may have an important function in urea reabsorption.
Title: Glycoforms of UT-A3 urea transporter with poly-N-acetyllactosamine glycosylation have enhanced transport activity.

The following Slc14a2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slc14a2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa00780	NM_001110270.1 Latest version!	Rattus norvegicus solute carrier family 14 member 2 (Slc14a2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
ORa04041	NM_177962.3 Latest version!	Rattus norvegicus solute carrier family 14 member 2 (Slc14a2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa04505	NM_019347.2 Latest version!	Rattus norvegicus solute carrier family 14 member 2 (Slc14a2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$545.30 $779.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Slc14a2 ( NM_001110270.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001103740.1 Rattus norvegicus solute carrier family 14 member 2 (Slc14a2), transcript variant 3, mRNA.

Price & Availability↑

CloneID	ORa00780
Clone ID Related Accession (Same CDS sequence)	NM_001110270.1
Accession Version	NM_001110270.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1194bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-03
Organism	Rattus norvegicus(Norway rat)
Product	urea transporter 2 isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from U09957.1, CK483468.1 and CK844529.1. Transcript Variant: This variant (3), also known as UT-A2 or UT2, contains a distinct 5' UTR and lacks multiple 5' coding exons, compared to variant 1. The resulting isoform (3) has a substantially shorter N-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U09957.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689597, SAMN02642745 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGGAGA GCTCTGAGAT AAAGGTAGAA ACCAACACAA CCAGGACTAC CTGGATCCAG 
AGCTCCATGA TCGCTGGGGG GAAGAGAGTC AGCAAAGCCC TCAGCTACAT CACAGGAGAG 
ATGAAGGAGT GCGGCGAGGG ACTTAAAGAC AAATCTCCAG TGTTCCAGTT TCTTGACTGG 
GTGCTCCGAG GCACGTCTCA GGTGATGTTT GTGAACAACC CTCTCAGTGG CATCCTCATC 
GTTCTTGGCC TCTTCGTGCA GAATCCCTGG TGGGCCATCT CCGGTTGCTT GGGCACCATC 
ATGTCCACCT TGACTGCCCT CATCCTGAGC CAGGACAAGT CGGCCATTGC AGCAGGACTC 
CATGGCTACA ATGGGGTGCT TGTGGGGCTC CTGATGGCCG TGTTCTCAGA CAAGGGCAAT 
TACTACTGGT GGCTGCTGCT CCCGGTCATC GTCATGTCCA TGACTTGCCC CATCCTCTCC 
AGTGCTCTGA GCACCGTCTT CAGCAAATGG GACCTCCCAG TCTTCACACT GCCCTTCAAC 
ATCGCCGTGA CCCTGTACCT GGCAGCCACG GGCCACTACA ATCTCTTCTT CCCCACGAAG 
CTGCTGCAGC CTGCAGTTAC CACACCCAAC ATCACCTGGT CAGATGTCCA AGTGCCTTTG 
CTTCTGAGAG CCATCCCCGT TGGAATCGGC CAAGTGTATG GCTGTGACAA TCCCTGGACT 
GGAGGCATCT TCCTCGTTGC TCTGTTCGTC TCTTCACCTC TCATCTGCTT GCACGCTGCC 
ATCGGATCCA CGATAGGGAT GTTAGCAGCA CTCAGCATTG CCACACCATT TGACTCCATC 
TACTTTGGCC TGTGTGGCTT CAATAGCACT CTGGCCTGTA TCGCTATTGG TGGCATGTTC 
TACGTCATCA CCTGGCAGAC GCACCTGCTC GCCATTGCCT GTGCCCTGTT TGCAGCCTAC 
CTGGGTGCTG CCCTGGCCAA CATGCTGTCT GTGTTTGGAT TACCACCCTG CACCTGGCCC 
TTCTGCCTCT CAGCGCTCAC CTTCCTCCTC CTCACAACCA ACAACCCTGG CATCTACAAG 
CTCCCGCTCA GCAAAGTCAC CTACCCAGAG GCCAACCGCA TCTACTTCCT GTCCCAGGAG 
AAAAACAGAA GGGCATCGAT GATAACAAAG TACCAGGCCT ACGACGTCTC CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001103740.1
CDS	929..2122
Translation	MEESSEIKVETNTTRTTWIQSSMIAGGKRVSKALSYITGEMKECGEGLKDKSPVFQFLDWVLRGTSQVMFVNNPLSGILIVLGLFVQNPWWAISGCLGTIMSTLTALILSQDKSAIAAGLHGYNGVLVGLLMAVFSDKGNYYWWLLLPVIVMSMTCPILSSALSTVFSKWDLPVFTLPFNIAVTLYLAATGHYNLFFPTKLLQPAVTTPNITWSDVQVPLLLRAIPVGIGQVYGCDNPWTGGIFLVALFVSSPLICLHAAIGSTIGMLAALSIATPFDSIYFGLCGFNSTLACIAIGGMFYVITWQTHLLAIACALFAAYLGAALANMLSVFGLPPCTWPFCLSALTFLLLTTNNPGIYKLPLSKVTYPEANRIYFLSQEKNRRASMITKYQAYDVS

Target ORF information:

RefSeq Version	NM_001110270.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 14 member 2 (Slc14a2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001110270.1

ORF Insert Sequence:

ATGGAGGAGA GCTCTGAGAT AAAGGTAGAA ACCAACACAA CCAGGACTAC CTGGATCCAG 
AGCTCCATGA TCGCTGGGGG GAAGAGAGTC AGCAAAGCCC TCAGCTACAT CACAGGAGAG 
ATGAAGGAGT GCGGCGAGGG ACTTAAAGAC AAATCTCCAG TGTTCCAGTT TCTTGACTGG 
GTGCTCCGAG GCACGTCTCA GGTGATGTTT GTGAACAACC CTCTCAGTGG CATCCTCATC 
GTTCTTGGCC TCTTCGTGCA GAATCCCTGG TGGGCCATCT CCGGTTGCTT GGGCACCATC 
ATGTCCACCT TGACTGCCCT CATCCTGAGC CAGGACAAGT CGGCCATTGC AGCAGGACTC 
CATGGCTACA ATGGGGTGCT TGTGGGGCTC CTGATGGCCG TGTTCTCAGA CAAGGGCAAT 
TACTACTGGT GGCTGCTGCT CCCGGTCATC GTCATGTCCA TGACTTGCCC CATCCTCTCC 
AGTGCTCTGA GCACCGTCTT CAGCAAATGG GACCTCCCAG TCTTCACACT GCCCTTCAAC 
ATCGCCGTGA CCCTGTACCT GGCAGCCACG GGCCACTACA ATCTCTTCTT CCCCACGAAG 
CTGCTGCAGC CTGCAGTTAC CACACCCAAC ATCACCTGGT CAGATGTCCA AGTGCCTTTG 
CTTCTGAGAG CCATCCCCGT TGGAATCGGC CAAGTGTATG GCTGTGACAA TCCCTGGACT 
GGAGGCATCT TCCTCGTTGC TCTGTTCGTC TCTTCACCTC TCATCTGCTT GCACGCTGCC 
ATCGGATCCA CGATAGGGAT GTTAGCAGCA CTCAGCATTG CCACACCATT TGACTCCATC 
TACTTTGGCC TGTGTGGCTT CAATAGCACT CTGGCCTGTA TCGCTATTGG TGGCATGTTC 
TACGTCATCA CCTGGCAGAC GCACCTGCTC GCCATTGCCT GTGCCCTGTT TGCAGCCTAC 
CTGGGTGCTG CCCTGGCCAA CATGCTGTCT GTGTTTGGAT TACCACCCTG CACCTGGCCC 
TTCTGCCTCT CAGCGCTCAC CTTCCTCCTC CTCACAACCA ACAACCCTGG CATCTACAAG 
CTCCCGCTCA GCAAAGTCAC CTACCCAGAG GCCAACCGCA TCTACTTCCT GTCCCAGGAG 
AAAAACAGAA GGGCATCGAT GATAACAAAG TACCAGGCCT ACGACGTCTC CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc14a2 ( NM_177962.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_808877.2 Rattus norvegicus solute carrier family 14 member 2 (Slc14a2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	ORa04041
Clone ID Related Accession (Same CDS sequence)	NM_177962.3
Accession Version	NM_177962.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1383bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-03
Organism	Rattus norvegicus(Norway rat)
Product	urea transporter 2 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF041788.1 and AF031642.1. On Nov 2, 2007 this sequence version replaced NM_177962.2. Transcript Variant: This variant (2), also known as UT-A3 or UT4, contains a distinct 3' CDS and 3' UTR, compared to variant 1. The resulting isoform (2) has a substantially shorter and distinct C-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF031642.1, AF041788.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN02642782 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGCGACC ATCCCCTGAA GGAGATGTCT GACAACAACC GCAGCCCCCT CTTGCCAGAG 
CCTCTTTCCA GCAGATACAA GTTGTATGAG TCAGAGCTAA GCAGCCCTAC CTGGCCTTCA 
AGCTCCCAGG ATACACACCC AGCCCTTCCC CTGCTGGAAA TGCCTGAAGA AAAGGATCTC 
CGATCATCGG ATGAAGACAG CCACATAGTG AAGATTGAAA AGCCCAACGA GCGGAGTAAA 
CGGAGAGAAA GCGAGTTGCC CCGCAGGGCT TCTGCAGGCC GGGGAGGCTT CAGCCTCTTC 
CAAGCTGTGA GCTACCTCAC TGGTGACATG AAGGAATGCA AGAACTGGCT GAAAGATAAG 
CCCCTGGTCC TTCAGTTCCT AGACTGGGTC CTGCGGGGAG CAGCTCAGGT GATGTTTGTC 
AACAACCCCC TTAGTGGGCT CATCATCTTC ATAGGGCTCC TGATCCAGAA TCCCTGGTGG 
ACGATTGCTG GGGCACTGGG GACAGTGGTC TCAACCTTGG CTGCCCTTGC CTTGAGCCAG 
GACAGGTCAG CCATCGCCTC TGGACTCCAT GGGTACAACG GGATGCTGGT GGGACTCCTG 
GTGGCTGTCT TCTCAGAGAA GTTAGACTAC TACTGGTGGC TTCTGTTTCC TGTGACCTTC 
GCATCCATGG CCTGCCCAGT TATTTCTAGT GCCTTGAGCA CCGTCTTCGC CAAGTGGGAC 
CTGCCAGTCT TCACACTGCC CTTCAACATC GCCTTAACAC TGTACCTGGC AGCTACGGGC 
CACTACAACC TTTTCTTCCC CACGACGCTT GTGAAGCCTG CGTCTTCAGC GCCCAACATC 
ACCTGGTCAG AGATTGAGAT GCCTTTGCTG TTACAAACCA TCCCCGTTGG GGTGGGCCAG 
GTCTACGGCT GTGACAACCC CTGGACAGGC GGCGTGATCC TGGTGGCTCT GTTTATCTCC 
TCTCCCCTCA TCTGTTTGCA CGCAGCCATA GGATCCATTG TGGGGCTGCT GGCAGCACTG 
ACGGTGGCCA CTCCCTTCGA GACGATCTAC ACGGGCCTTT GGAGCTACAA CTGTGTCCTC 
TCCTGTGTCG CCATTGGAGG CATGTTCTAC GTACTCACCT GGCAGACACA CCTGTTGGCA 
CTTGTCTGTG CCCTGTTCTG TGCGTACACG GGAGCGGCCC TCTCCAATAT GATGGCAGTG 
GTTGGTGTGC CACCGGGCAC CTGGGCCTTC TGTCTCTCCA CCCTCACCTT CCTTCTCCTC 
ACAAGCAACA ACCCTGGCAT CCACAAGCTC CCACTCAGCA AAGTCACCTA CCCAGAGGCC 
AACCGCATCT ACTTCCTGAC AGCGAAACGC AGTGACGAGC AGAAGCCCCC CAATGGTGAC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_808877.2
CDS	377..1759
Translation	MSDHPLKEMSDNNRSPLLPEPLSSRYKLYESELSSPTWPSSSQDTHPALPLLEMPEEKDLRSSDEDSHIVKIEKPNERSKRRESELPRRASAGRGGFSLFQAVSYLTGDMKECKNWLKDKPLVLQFLDWVLRGAAQVMFVNNPLSGLIIFIGLLIQNPWWTIAGALGTVVSTLAALALSQDRSAIASGLHGYNGMLVGLLVAVFSEKLDYYWWLLFPVTFASMACPVISSALSTVFAKWDLPVFTLPFNIALTLYLAATGHYNLFFPTTLVKPASSAPNITWSEIEMPLLLQTIPVGVGQVYGCDNPWTGGVILVALFISSPLICLHAAIGSIVGLLAALTVATPFETIYTGLWSYNCVLSCVAIGGMFYVLTWQTHLLALVCALFCAYTGAALSNMMAVVGVPPGTWAFCLSTLTFLLLTSNNPGIHKLPLSKVTYPEANRIYFLTAKRSDEQKPPNGD

Target ORF information:

RefSeq Version	NM_177962.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 14 member 2 (Slc14a2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_177962.3

ORF Insert Sequence:

ATGAGCGACC ATCCCCTGAA GGAGATGTCT GACAACAACC GCAGCCCCCT CTTGCCAGAG 
CCTCTTTCCA GCAGATACAA GTTGTATGAG TCAGAGCTAA GCAGCCCTAC CTGGCCTTCA 
AGCTCCCAGG ATACACACCC AGCCCTTCCC CTGCTGGAAA TGCCTGAAGA AAAGGATCTC 
CGATCATCGG ATGAAGACAG CCACATAGTG AAGATTGAAA AGCCCAACGA GCGGAGTAAA 
CGGAGAGAAA GCGAGTTGCC CCGCAGGGCT TCTGCAGGCC GGGGAGGCTT CAGCCTCTTC 
CAAGCTGTGA GCTACCTCAC TGGTGACATG AAGGAATGCA AGAACTGGCT GAAAGATAAG 
CCCCTGGTCC TTCAGTTCCT AGACTGGGTC CTGCGGGGAG CAGCTCAGGT GATGTTTGTC 
AACAACCCCC TTAGTGGGCT CATCATCTTC ATAGGGCTCC TGATCCAGAA TCCCTGGTGG 
ACGATTGCTG GGGCACTGGG GACAGTGGTC TCAACCTTGG CTGCCCTTGC CTTGAGCCAG 
GACAGGTCAG CCATCGCCTC TGGACTCCAT GGGTACAACG GGATGCTGGT GGGACTCCTG 
GTGGCTGTCT TCTCAGAGAA GTTAGACTAC TACTGGTGGC TTCTGTTTCC TGTGACCTTC 
GCATCCATGG CCTGCCCAGT TATTTCTAGT GCCTTGAGCA CCGTCTTCGC CAAGTGGGAC 
CTGCCAGTCT TCACACTGCC CTTCAACATC GCCTTAACAC TGTACCTGGC AGCTACGGGC 
CACTACAACC TTTTCTTCCC CACGACGCTT GTGAAGCCTG CGTCTTCAGC GCCCAACATC 
ACCTGGTCAG AGATTGAGAT GCCTTTGCTG TTACAAACCA TCCCCGTTGG GGTGGGCCAG 
GTCTACGGCT GTGACAACCC CTGGACAGGC GGCGTGATCC TGGTGGCTCT GTTTATCTCC 
TCTCCCCTCA TCTGTTTGCA CGCAGCCATA GGATCCATTG TGGGGCTGCT GGCAGCACTG 
ACGGTGGCCA CTCCCTTCGA GACGATCTAC ACGGGCCTTT GGAGCTACAA CTGTGTCCTC 
TCCTGTGTCG CCATTGGAGG CATGTTCTAC GTACTCACCT GGCAGACACA CCTGTTGGCA 
CTTGTCTGTG CCCTGTTCTG TGCGTACACG GGAGCGGCCC TCTCCAATAT GATGGCAGTG 
GTTGGTGTGC CACCGGGCAC CTGGGCCTTC TGTCTCTCCA CCCTCACCTT CCTTCTCCTC 
ACAAGCAACA ACCCTGGCAT CCACAAGCTC CCACTCAGCA AAGTCACCTA CCCAGAGGCC 
AACCGCATCT ACTTCCTGAC AGCGAAACGC AGTGACGAGC AGAAGCCCCC CAATGGTGAC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc14a2 ( NM_019347.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_062220.2 Rattus norvegicus solute carrier family 14 member 2 (Slc14a2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	ORa04505
Clone ID Related Accession (Same CDS sequence)	NM_019347.2
Accession Version	NM_019347.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2790bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-03
Organism	Rattus norvegicus(Norway rat)
Product	urea transporter 2 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF041788.1, U77971.1 and CK844529.1. On Nov 2, 2007 this sequence version replaced NM_019347.1. Transcript Variant: This variant (1), also known as UT1, UT-A1, or VRUT, represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U77971.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGCGACC ATCCCCTGAA GGAGATGTCT GACAACAACC GCAGCCCCCT CTTGCCAGAG 
CCTCTTTCCA GCAGATACAA GTTGTATGAG TCAGAGCTAA GCAGCCCTAC CTGGCCTTCA 
AGCTCCCAGG ATACACACCC AGCCCTTCCC CTGCTGGAAA TGCCTGAAGA AAAGGATCTC 
CGATCATCGG ATGAAGACAG CCACATAGTG AAGATTGAAA AGCCCAACGA GCGGAGTAAA 
CGGAGAGAAA GCGAGTTGCC CCGCAGGGCT TCTGCAGGCC GGGGAGGCTT CAGCCTCTTC 
CAAGCTGTGA GCTACCTCAC TGGTGACATG AAGGAATGCA AGAACTGGCT GAAAGATAAG 
CCCCTGGTCC TTCAGTTCCT AGACTGGGTC CTGCGGGGAG CAGCTCAGGT GATGTTTGTC 
AACAACCCCC TTAGTGGGCT CATCATCTTC ATAGGGCTCC TGATCCAGAA TCCCTGGTGG 
ACGATTGCTG GGGCACTGGG GACAGTGGTC TCAACCTTGG CTGCCCTTGC CTTGAGCCAG 
GACAGGTCAG CCATCGCCTC TGGACTCCAT GGGTACAACG GGATGCTGGT GGGACTCCTG 
GTGGCTGTCT TCTCAGAGAA GTTAGACTAC TACTGGTGGC TTCTGTTTCC TGTGACCTTC 
GCATCCATGG CCTGCCCAGT TATTTCTAGT GCCTTGAGCA CCGTCTTCGC CAAGTGGGAC 
CTGCCAGTCT TCACACTGCC CTTCAACATC GCCTTAACAC TGTACCTGGC AGCTACGGGC 
CACTACAACC TTTTCTTCCC CACGACGCTT GTGAAGCCTG CGTCTTCAGC GCCCAACATC 
ACCTGGTCAG AGATTGAGAT GCCTTTGCTG TTACAAACCA TCCCCGTTGG GGTGGGCCAG 
GTCTACGGCT GTGACAACCC CTGGACAGGC GGCGTGATCC TGGTGGCTCT GTTTATCTCC 
TCTCCCCTCA TCTGTTTGCA CGCAGCCATA GGATCCATTG TGGGGCTGCT GGCAGCACTG 
ACGGTGGCCA CTCCCTTCGA GACGATCTAC ACGGGCCTTT GGAGCTACAA CTGTGTCCTC 
TCCTGTGTCG CCATTGGAGG CATGTTCTAC GTACTCACCT GGCAGACACA CCTGTTGGCA 
CTTGTCTGTG CCCTGTTCTG TGCGTACACG GGAGCGGCCC TCTCCAATAT GATGGCAGTG 
GTTGGTGTGC CACCGGGCAC CTGGGCCTTC TGTCTCTCCA CCCTCACCTT CCTTCTCCTC 
ACAAGCAACA ACCCTGGCAT CCACAAGCTC CCACTCAGCA AAGTCACCTA CCCAGAGGCC 
AACCGCATCT ACTTCCTGAC AGCGAAACGC AGTGACGAGC AGAAGCCCCC CAATGGTGGC 
GGTGGAGAAC AGTCACACGG AGGAGGCCAG CGGAAGGCAG AGGAGGGCTC CGAGACCGTG 
TTCCCCAGGC GTAAGAGCGT GTTCCATATC GAGTGGTCAT CCATCCGGAG GAGGAGCAAA 
GTGTTTGGAA AAAGTGAACA CCAAGAGAGA CAAACCAAAG AGCCACTCCC CTACCTGTAT 
CGGAAGCCCA CAGTGGAACT CTTGGACCTG AACACCATGG AGGAGAGCTC TGAGATAAAG 
GTAGAAACCA ACACAACCAG GACTACCTGG ATCCAGAGCT CCATGATCGC TGGGGGGAAG 
AGAGTCAGCA AAGCCCTCAG CTACATCACA GGAGAGATGA AGGAGTGCGG CGAGGGACTT 
AAAGACAAAT CTCCAGTGTT CCAGTTTCTT GACTGGGTGC TCCGAGGCAC GTCTCAGGTG 
ATGTTTGTGA ACAACCCTCT CAGTGGCATC CTCATCGTTC TTGGCCTCTT CGTGCAGAAT 
CCCTGGTGGG CCATCTCCGG TTGCTTGGGC ACCATCATGT CCACCTTGAC TGCCCTCATC 
CTGAGCCAGG ACAAGTCGGC CATTGCAGCA GGACTCCATG GCTACAATGG GGTGCTTGTG 
GGGCTCCTGA TGGCCGTGTT CTCAGACAAG GGCAATTACT ACTGGTGGCT GCTGCTCCCG 
GTCATCGTCA TGTCCATGAC TTGCCCCATC CTCTCCAGTG CTCTGAGCAC CGTCTTCAGC 
AAATGGGACC TCCCAGTCTT CACACTGCCC TTCAACATCG CCGTGACCCT GTACCTGGCA 
GCCACGGGCC ACTACAATCT CTTCTTCCCC ACGAAGCTGC TGCAGCCTGC AGTTACCACA 
CCCAACATCA CCTGGTCAGA TGTCCAAGTG CCTTTGCTTC TGAGAGCCAT CCCCGTTGGA 
ATCGGCCAAG TGTATGGCTG TGACAATCCC TGGACTGGAG GCATCTTCCT CGTTGCTCTG 
TTCGTCTCTT CACCTCTCAT CTGCTTGCAC GCTGCCATCG GATCCACGAT AGGGATGTTA 
GCAGCACTCA GCATTGCCAC ACCATTTGAC TCCATCTACT TTGGCCTGTG TGGCTTCAAT 
AGCACTCTGG CCTGTATCGC TATTGGTGGC ATGTTCTACG TCATCACCTG GCAGACGCAC 
CTGCTCGCCA TTGCCTGTGC CCTGTTTGCA GCCTACCTGG GTGCTGCCCT GGCCAACATG 
CTGTCTGTGT TTGGATTACC ACCCTGCACC TGGCCCTTCT GCCTCTCAGC GCTCACCTTC 
CTCCTCCTCA CAACCAACAA CCCTGGCATC TACAAGCTCC CGCTCAGCAA AGTCACCTAC 
CCAGAGGCCA ACCGCATCTA CTTCCTGTCC CAGGAGAAAA ACAGAAGGGC ATCGATGATA 
ACAAAGTACC AGGCCTACGA CGTCTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_062220.2
CDS	377..3166
Translation	MSDHPLKEMSDNNRSPLLPEPLSSRYKLYESELSSPTWPSSSQDTHPALPLLEMPEEKDLRSSDEDSHIVKIEKPNERSKRRESELPRRASAGRGGFSLFQAVSYLTGDMKECKNWLKDKPLVLQFLDWVLRGAAQVMFVNNPLSGLIIFIGLLIQNPWWTIAGALGTVVSTLAALALSQDRSAIASGLHGYNGMLVGLLVAVFSEKLDYYWWLLFPVTFASMACPVISSALSTVFAKWDLPVFTLPFNIALTLYLAATGHYNLFFPTTLVKPASSAPNITWSEIEMPLLLQTIPVGVGQVYGCDNPWTGGVILVALFISSPLICLHAAIGSIVGLLAALTVATPFETIYTGLWSYNCVLSCVAIGGMFYVLTWQTHLLALVCALFCAYTGAALSNMMAVVGVPPGTWAFCLSTLTFLLLTSNNPGIHKLPLSKVTYPEANRIYFLTAKRSDEQKPPNGGGGEQSHGGGQRKAEEGSETVFPRRKSVFHIEWSSIRRRSKVFGKSEHQERQTKEPLPYLYRKPTVELLDLNTMEESSEIKVETNTTRTTWIQSSMIAGGKRVSKALSYITGEMKECGEGLKDKSPVFQFLDWVLRGTSQVMFVNNPLSGILIVLGLFVQNPWWAISGCLGTIMSTLTALILSQDKSAIAAGLHGYNGVLVGLLMAVFSDKGNYYWWLLLPVIVMSMTCPILSSALSTVFSKWDLPVFTLPFNIAVTLYLAATGHYNLFFPTKLLQPAVTTPNITWSDVQVPLLLRAIPVGIGQVYGCDNPWTGGIFLVALFVSSPLICLHAAIGSTIGMLAALSIATPFDSIYFGLCGFNSTLACIAIGGMFYVITWQTHLLAIACALFAAYLGAALANMLSVFGLPPCTWPFCLSALTFLLLTTNNPGIYKLPLSKVTYPEANRIYFLSQEKNRRASMITKYQAYDVS

Target ORF information:

RefSeq Version	NM_019347.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 14 member 2 (Slc14a2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019347.2

ORF Insert Sequence:

ATGAGCGACC ATCCCCTGAA GGAGATGTCT GACAACAACC GCAGCCCCCT CTTGCCAGAG 
CCTCTTTCCA GCAGATACAA GTTGTATGAG TCAGAGCTAA GCAGCCCTAC CTGGCCTTCA 
AGCTCCCAGG ATACACACCC AGCCCTTCCC CTGCTGGAAA TGCCTGAAGA AAAGGATCTC 
CGATCATCGG ATGAAGACAG CCACATAGTG AAGATTGAAA AGCCCAACGA GCGGAGTAAA 
CGGAGAGAAA GCGAGTTGCC CCGCAGGGCT TCTGCAGGCC GGGGAGGCTT CAGCCTCTTC 
CAAGCTGTGA GCTACCTCAC TGGTGACATG AAGGAATGCA AGAACTGGCT GAAAGATAAG 
CCCCTGGTCC TTCAGTTCCT AGACTGGGTC CTGCGGGGAG CAGCTCAGGT GATGTTTGTC 
AACAACCCCC TTAGTGGGCT CATCATCTTC ATAGGGCTCC TGATCCAGAA TCCCTGGTGG 
ACGATTGCTG GGGCACTGGG GACAGTGGTC TCAACCTTGG CTGCCCTTGC CTTGAGCCAG 
GACAGGTCAG CCATCGCCTC TGGACTCCAT GGGTACAACG GGATGCTGGT GGGACTCCTG 
GTGGCTGTCT TCTCAGAGAA GTTAGACTAC TACTGGTGGC TTCTGTTTCC TGTGACCTTC 
GCATCCATGG CCTGCCCAGT TATTTCTAGT GCCTTGAGCA CCGTCTTCGC CAAGTGGGAC 
CTGCCAGTCT TCACACTGCC CTTCAACATC GCCTTAACAC TGTACCTGGC AGCTACGGGC 
CACTACAACC TTTTCTTCCC CACGACGCTT GTGAAGCCTG CGTCTTCAGC GCCCAACATC 
ACCTGGTCAG AGATTGAGAT GCCTTTGCTG TTACAAACCA TCCCCGTTGG GGTGGGCCAG 
GTCTACGGCT GTGACAACCC CTGGACAGGC GGCGTGATCC TGGTGGCTCT GTTTATCTCC 
TCTCCCCTCA TCTGTTTGCA CGCAGCCATA GGATCCATTG TGGGGCTGCT GGCAGCACTG 
ACGGTGGCCA CTCCCTTCGA GACGATCTAC ACGGGCCTTT GGAGCTACAA CTGTGTCCTC 
TCCTGTGTCG CCATTGGAGG CATGTTCTAC GTACTCACCT GGCAGACACA CCTGTTGGCA 
CTTGTCTGTG CCCTGTTCTG TGCGTACACG GGAGCGGCCC TCTCCAATAT GATGGCAGTG 
GTTGGTGTGC CACCGGGCAC CTGGGCCTTC TGTCTCTCCA CCCTCACCTT CCTTCTCCTC 
ACAAGCAACA ACCCTGGCAT CCACAAGCTC CCACTCAGCA AAGTCACCTA CCCAGAGGCC 
AACCGCATCT ACTTCCTGAC AGCGAAACGC AGTGACGAGC AGAAGCCCCC CAATGGTGGC 
GGTGGAGAAC AGTCACACGG AGGAGGCCAG CGGAAGGCAG AGGAGGGCTC CGAGACCGTG 
TTCCCCAGGC GTAAGAGCGT GTTCCATATC GAGTGGTCAT CCATCCGGAG GAGGAGCAAA 
GTGTTTGGAA AAAGTGAACA CCAAGAGAGA CAAACCAAAG AGCCACTCCC CTACCTGTAT 
CGGAAGCCCA CAGTGGAACT CTTGGACCTG AACACCATGG AGGAGAGCTC TGAGATAAAG 
GTAGAAACCA ACACAACCAG GACTACCTGG ATCCAGAGCT CCATGATCGC TGGGGGGAAG 
AGAGTCAGCA AAGCCCTCAG CTACATCACA GGAGAGATGA AGGAGTGCGG CGAGGGACTT 
AAAGACAAAT CTCCAGTGTT CCAGTTTCTT GACTGGGTGC TCCGAGGCAC GTCTCAGGTG 
ATGTTTGTGA ACAACCCTCT CAGTGGCATC CTCATCGTTC TTGGCCTCTT CGTGCAGAAT 
CCCTGGTGGG CCATCTCCGG TTGCTTGGGC ACCATCATGT CCACCTTGAC TGCCCTCATC 
CTGAGCCAGG ACAAGTCGGC CATTGCAGCA GGACTCCATG GCTACAATGG GGTGCTTGTG 
GGGCTCCTGA TGGCCGTGTT CTCAGACAAG GGCAATTACT ACTGGTGGCT GCTGCTCCCG 
GTCATCGTCA TGTCCATGAC TTGCCCCATC CTCTCCAGTG CTCTGAGCAC CGTCTTCAGC 
AAATGGGACC TCCCAGTCTT CACACTGCCC TTCAACATCG CCGTGACCCT GTACCTGGCA 
GCCACGGGCC ACTACAATCT CTTCTTCCCC ACGAAGCTGC TGCAGCCTGC AGTTACCACA 
CCCAACATCA CCTGGTCAGA TGTCCAAGTG CCTTTGCTTC TGAGAGCCAT CCCCGTTGGA 
ATCGGCCAAG TGTATGGCTG TGACAATCCC TGGACTGGAG GCATCTTCCT CGTTGCTCTG 
TTCGTCTCTT CACCTCTCAT CTGCTTGCAC GCTGCCATCG GATCCACGAT AGGGATGTTA 
GCAGCACTCA GCATTGCCAC ACCATTTGAC TCCATCTACT TTGGCCTGTG TGGCTTCAAT 
AGCACTCTGG CCTGTATCGC TATTGGTGGC ATGTTCTACG TCATCACCTG GCAGACGCAC 
CTGCTCGCCA TTGCCTGTGC CCTGTTTGCA GCCTACCTGG GTGCTGCCCT GGCCAACATG 
CTGTCTGTGT TTGGATTACC ACCCTGCACC TGGCCCTTCT GCCTCTCAGC GCTCACCTTC 
CTCCTCCTCA CAACCAACAA CCCTGGCATC TACAAGCTCC CGCTCAGCAA AGTCACCTAC 
CCAGAGGCCA ACCGCATCTA CTTCCTGTCC CAGGAGAAAA ACAGAAGGGC ATCGATGATA 
ACAAAGTACC AGGCCTACGA CGTCTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Identification of UT-A1- and AQP2-interacting proteins in rat inner medullary collecting duct.
American journal of physiology. Cell physiology314(1)C99-C117(2018 Jan)
Chou CL,Hwang G,Hageman DJ,Han L,Agrawal P,Pisitkun T,Knepper MA

Alternative channels for urea in the inner medulla of the rat kidney.
American journal of physiology. Renal physiology309(11)F916-24(2015 Dec)
Nawata CM,Dantzler WH,Pannabecker TL

Downregulation of urea transporter UT-A1 activity by 14-3-3 protein.
American journal of physiology. Renal physiology309(1)F71-8(2015 Jul)
Feng X,Li Z,Du Y,Fu H,Klein JD,Cai H,Sands JM,Chen G

Structure-activity analysis of thiourea analogs as inhibitors of UT-A and UT-B urea transporters.
Biochimica et biophysica acta1848(5)1075-80(2015 May)
Esteva-Font C,Phuan PW,Lee S,Su T,Anderson MO,Verkman AS

Vasopressin regulation of multisite phosphorylation of UT-A1 in the inner medullary collecting duct.
American journal of physiology. Renal physiology308(1)F49-55(2015 Jan)
Hoban CA,Black LN,Ordas RJ,Gumina DL,Pulous FE,Sim JH,Sands JM,Blount MA

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

Slc14a2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報