Ncor1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ncor1
Entrez Gene ID	54299
Full Name	nuclear receptor co-repressor 1
Synonyms	Rxrip13
General protein information	Preferred Names nuclear receptor co-repressor 1 Names nuclear receptor corepressor 1 N-CoR N-CoR1 N-Cor/SMRT corepressor, Rip13 NCoR
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q23
Summary	expressed in skeletal muscle [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001271103.1	NP_001258032.1	nuclear receptor corepressor 1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	NCOR1	NP_001179988.1
Xenopus tropicalis (tropical clawed frog)	ncor1	NP_001027513.1
Homo sapiens (human)	NCOR1	NP_006302.2
Rattus norvegicus (Norway rat)	Ncor1	NP_001258032.1
Mus musculus (house mouse)	Ncor1	NP_001239242.1
Gallus gallus (chicken)	NCOR1	XP_004946715.1
Pan troglodytes (chimpanzee)	NCOR1	XP_003318150.1
Danio rerio (zebrafish)	ncor1	NP_956570.2
	LOC696351	XP_002808164.1
Canis lupus familiaris (dog)	NCOR1	XP_005620154.1

Gene Ontology
Bibliography

Related articles in PubMed

NCoR negatively regulates adipogenic differentiation of mesenchymal stem cells.
Hong-Wei G, Lan L, De-Guo X, Zhong-Hao L, Peng R, Zhi-Qiang L, Guo-Qiang S, Ming-Zhi G
In vitro cellular & developmental biology. Animal51(7)749-58(2015 Aug)

Circadian regulation of Tshb gene expression by Rev-Erb? (NR1D1) and nuclear corepressor 1 (NCOR1).
Aninye IO, Matsumoto S, Sidhaye AR, Wondisford FE
The Journal of biological chemistry289(24)17070-7(2014 Jun)

Thyroid hormone signaling in vivo requires a balance between coactivators and corepressors.
Vella KR, Ramadoss P, Costa-E-Sousa RH, Astapova I, Ye FD, Holtz KA, Harris JC, Hollenberg AN
Molecular and cellular biology34(9)1564-75(2014 May)

SMRT-mediated co-shuttling enables export of class IIa HDACs independent of their CaM kinase phosphorylation sites.
Soriano FX, Chawla S, Skehel P, Hardingham GE
Journal of neurochemistry124(1)26-35(2013 Jan)

A molecular mechanism underlying ovarian dysfunction of polycystic ovary syndrome: hyperandrogenism induces epigenetic alterations in the granulosa cells.
Qu F, Wang FF, Yin R, Ding GL, El-Prince M, Gao Q, Shi BW, Pan HH, Huang YT, Jin M, Leung PC, Sheng JZ, Huang HF
Journal of molecular medicine (Berlin, Germany)90(8)911-23(2012 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

NCoR negatively regulates adipogenic differentiation of mesenchymal stem cells.
Title: NCoR negatively regulates adipogenic differentiation of mesenchymal stem cells.

SMRT-mediated co-shuttling enables export of class IIa HDACs independent of their CaM kinase phosphorylation sites.
Title: SMRT-mediated co-shuttling enables export of class IIa HDACs independent of their CaM kinase phosphorylation sites.

PCOS rat models also showed alterations of PPARG1, NCOR1, and HDAC3 mRNA expression and methylation changes of PPARG1 and NCOR1, consistent with the results from humans.
Title: A molecular mechanism underlying ovarian dysfunction of polycystic ovary syndrome: hyperandrogenism induces epigenetic alterations in the granulosa cells.

SMRT's RD4 region can recruit factors capable of mediating nuclear export of SMRT, but whose function and/or recruitment is suppressed by HDAC3 activity
Title: In cortical neurons HDAC3 activity suppresses RD4-dependent SMRT export.

TRbeta1, NCoR-1, and the recently identified DOR/TP53INP2 are abundantly expressed and down-regulated in liver cells during APR.
Title: Changes in gene expression of DOR and other thyroid hormone receptors in rat liver during acute-phase response.

The following Ncor1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ncor1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa10258	NM_001271103.1 Latest version!	Rattus norvegicus nuclear receptor co-repressor 1 (Ncor1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$1301.30 $1859.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ncor1 ( NM_001271103.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001258032.1 Rattus norvegicus nuclear receptor co-repressor 1 (Ncor1), mRNA.

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CloneID	ORa10258
Clone ID Related Accession (Same CDS sequence)	NM_001271103.1
Accession Version	NM_001271103.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 7245bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Rattus norvegicus(Norway rat)
Product	nuclear receptor corepressor 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07029736.1, AABR07029735.1, AABR07029734.1 and AABR07029733.1. On or before Sep 1, 2012 this sequence version replaced XM_577103.4, XM_001077495.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGTCAAGTT CAGGTTACCC TCCCAACCAA GGAGCTTTCA GCACAGAGCA AAGTCGTTAT 
CCTTCACAGT CTGTCCAGTA TACCTTTCCC AGTACCCGGC ACCAGCAGGA ATTTGCAGTT 
CCTGACTATC GCTCTTCTCA CATCGAAGTT AGTCAGGCAT CGCAGCTCTT ACAGCAGCAG 
CAGCAGCAGC AGCAGCTTCG AAGGCGACCT TCCTTGCTTT CAGAATTTCA CCCAGGTTCT 
GACAGGCCTC AAGAGAGAAG AACTGGATAT GAACAGTTTC ACTCAGGACC CTCACCAGTG 
GATCATGATT CCTTGGAGTC CAAGCGTCCA CGCCTGGAGC CAGTTTCTGA TGCCCATTTC 
CAGCGTGTTA GTGCTGCGGT TTTACCTTTA GTTCACACGC TGCCAGAGGG GTTGAGGGCG 
TCTGCAGATG CTAAGAAGGA TTCGGCATTT GGAGGCAAAC ATGAAGCTCC ATCCTCTCCA 
TTGGCTGGGC AACCATGTGG AGATGATCAA AACGCTTCAC CTTCAAAGCT CTCAAAGGAA 
GAGTTAATAC AGAGTATGGA CCGGGTAGAC AGAGAGATTG CAAAAGTAGA GCAGCAGATC 
CTTAAATTGA AAAAGAAACA ACAACAGCTA GAAGAAGAAG CAGCTAAGCC TCCTGAGCCG 
GAGAAGCCTG TGTCCCCTCC TCCTGTGGAA CAGAAACACC GTAGTATTGT CCAAATTATT 
TATGATGAGA ATCGGAAAAA AGCTGAAGAA GCTCATAAAA TATTTGAAGG TCTTGGCCCA 
AAAGTTGAAT TGCCACTCTA TAACCAGCCG TCAGATACCA AGGTGTACCA TGAGAACATC 
AAGACAAACC AGGTGATGAG GAAAAAACTC ATTTTATTTT TTAAAAGAAG AAATCATGCA 
AGAAAACAAA GGGAACAAAA AATCTGCCAG CGTTATGATC AACTCATGGA GGCATGGGAG 
AAAAAAGTGG ACAGAATAGA AAATAATCCT CGGAGGAAAG CAAAAGAAAG CAAAACAAGG 
GAATACTATG AGAAGCAGTT TCCAGAAATT CGAAAACAAA GAGAACAACA AGAAAGATTT 
CAGCGAGTTG GTCAGAGGGG AGCTGGTCTT TCAGCCACCA TTGCTAGGAG TGAGCATGAG 
ATTTCCGAAA TTATTGATGG CCTTTCTGAG CAGGAGAATA ATGAGAAACA AATGCGGCAG 
CTTTCTGTGA TTCCCCCGAT GATGTTTGAT GCAGAACAAA GAAGGGTCAA GTTCATCAAT 
ATGAATGGGC TCATGGAGGA TCCAATGAAG GTTTATAAAG ACAGACAGTT TATGAATGTT 
TGGACTGACC ACGAAAAGGA GATCTTTAAG GACAAGTTTA TCCAGCACCC AAAAAACTTT 
GGACTAATTG CATCCTATTT GGAAAGGAAG AGCGTGCCTG ATTGTGTTTT ATATTACTAT 
TTAACCAAGA AAAACGAGAA TTATAAAGCC CTTGTGAGAA GAAATTATGG GAAACGCAGA 
GGCAGAAATC AGCAGATTGC CCGTCCCTCA CAAGAAGAAA AAGTAGAAGA AAAAGAAGAG 
GATAAAGCAG AAAAAATGGA GAAAAAGGAA GAAGAAAAGA AGGATGATGA AGAAAAAGAT 
GAGAAGGAAG AGTCTAAAGA AACAACCAAG GAAAAGGATA GAACAGAAGC CACAGCAGAA 
GAAACTGAGG AGAGAGAGCA GGTCACTCCA AGGGGGCGAA AGACTGCTAA CAGCCAAGGG 
CGTCGGAAGG GCCGGATCAC CAGGTCCATG ACAAGTGAAG CTGCAGCTGC CAGTGCTGCT 
GCTGCAGCCA CTGAGGAGCC CCCTCCACCG CTGCCACCAC CCCCAGAGCC CGTTTCTACA 
GAACCAGTTG AGACTTCAAG ATGGACGGAA GAAGAAATGG AAGTTGCTAA AAAAGGTAAT 
ATACAGCAAT GTATAATATA CAACAGTGCT TCACGAAAAC CCCGTGAGGA ACGAGATGTG 
TCTCAGTGTG AAAGTGTTGC TTCCACTGTG TCTGCCCAGG AGGATGAAGA TATTGAAGCC 
TCGAATGAGG AGGAGAATCC AGAAGATAGT GAAGGTGCTG AAAATAGTTC TGATACAGAA 
AGTGCTCCCT CTCCTTCACC AGTTGAAGCT GCCAAGTCCA GTGAAGACAG CAGTGAAAAT 
GCTGCTTCTC GAGGAAACAC CGAACCTGTG GCTGAGCTTG AGGCCACCAC TGACCCTGCA 
CCCTGTGCAT CTCCCTCTTC AGCAGTTCCA ACCACAAAAC CAGCAGAAAG TGAAAGCGTG 
GAGGCCCAGG TGACTGACAG CGCCAGTGTG GAGACCGCAG AGCCGATGGA TGTAGACCAT 
GAGGAGTGCG GTGCCCAAGG CAGTTCTGTT CTTGATCCAC CAGCCCCTAC CAAAGCTGAC 
TCCGTGGACC CAGAAATACA GGTACCAGAA AACACTGCAT CTAAAGGTGA AGGGGATGCC 
AAGGACAGAG ACTTGGAGAG CGCCAGTGAG AAGACAGAGG CTAGAGATGA AGACTTGGTA 
GTGGCTGAGC AGATGCAGAG GCCTGAACCA CAGTCAGACA ACGACTCCAG TGCCACATGC 
AGTGCAGACG AGGATGTCGA TGGAGAGCCA GAGAGGCAGA GAGTGTTTCC CATGGATGCA 
AAGCCTTCAC TGTTAAATCC TCCAGGATCA ATACTAATCT CATCCCCCAT TAAACCAAAC 
CCATTGGATC TGCCACAGCT TCAGCATCGA GCTGCTGTTA TTCCACCAAT GGTTTCTTGC 
ACCCCATGTA ATATACCAAT TGGAACACCT GTAAGTGGCT ATGCTCTTTA CCAACGGCAC 
ATTAAGGCCA TGCATGAGTC AGCACTCCTG GAGGAACAGC GGCAGAGGCA AGAACAGATA 
GACTTGGAGT GCAGAAGTTC TACAAGCCCG TGTGGCACTT CTAAGAGTCC AAACAGGGAA 
TGGGAAGTCC TCCAACCTGC TCCACATCAA GTGATAACTA ACCTTCCTGA AGGGGTTCGG 
CTTCCAACAA CACGACCAAC CAGGCCACCA CCTCCCCTCA TCCCATCGTC CAAAACCACA 
GTAGCATCAG AAAAACCATC CTTTATAATG GGAGGGTCCA TCTCACAGGG AACTCCTGGC 
ACTTACTTGA CTTCTCATAG TCAGGCTTAT ACTCCGGAAG CAGCTAAGCC CTCAGTGGGG 
TCTATCTCTC TTGGATTGCC ACGGCAGCAG GAATCTACCA AGTCAGCTCC TTTGACCTAC 
ATCAAGCAGG AAGAATTTTC TCCACGAAGC CAAAACTCAC AGCCTGAGGG TTTATTGGTG 
AGAGCGCAGC ATGAAGGTGT GGTCAGAGGC ACTGCAGGGG CTGTCCAAGA AGGAAGTATA 
ACTCGGGGAA CTCCAGCCAG CAAGATCTCA GTGGAGAGCA TTTCATCCTT GCGGGGCTCT 
ATTACCCAGG GGACCCCAGC TCTGCCCCAG GCTGGCATAC CAACAGAGGC TTTGGTGAAG 
GGACCTGTTT CCAGGATGCC AATTGAGGAA AGCAGTCCTG AGAAGGTCAG AGAGGAAGCT 
GCATCCAAAG GCCATGTCAT CTATGAAGGC AAAAGTGGAC ATATCTTATC ATATGACAAT 
ATTAAGAATG CCCGAGAAGG GACTCGGAGT CCAAGAACAG CTCATGAAAT GAGTTTAAAA 
AGAAGCTATG AGTCAGTGGA AGGAAATGTA AAGCAAGGCA TGTCGATGAG GGAGTCTCCT 
GTGTCAGCAG CACCTTTAGA GGAAAGGACT GTGCTGTCTG GTTCCATAAT GCAGGGCACA 
CCTAGAGCAA CAGCCGAAAG CTTTGAAGAT GGCCTTAAAT ACCCCAAACA GATAAAAAGG 
GAAAGCCCTC CTAGTCGAGC ATTTGAAGGT GCCATTACCA AAGGAAAACC ATACGATGGC 
ATCACCACCA TCAAAGAAAT GGGGCGTTCC ATTCATGAAA TTCCAAGACA AGATATTCTA 
ACTCAGGAAA GCCGGAAAAC TCCAGAAGTG GTCCAGAGCA CGAGGCCAAT AATTGAGGGT 
TCCATTTCCC AGGGCACACC AATAAAATTT GACAACAACT CAGGTCAATC AGCTATCAAA 
CACAATGTGA AGTCCTTAAT CACAGGGCCT AGCAAACTAC CCCGAGGAAT GCTGGAAATT 
GTACCAGAAA ACATAAAAGT AGTAGAACGG GGAAAATATG AGGACGTGAA AGCAGGCGAA 
CCAGTGCGAC CCCGGCACAC GTCAGTGGTG AGCTCTGGCC CCTCCGTTCT CAGGTCTACA 
CTTCATGAAG CTCCCAAAGC ACAGTTGAGC CCGGGAATCT ATGATGACAG CAGTGCTCGC 
AGGACTCCTG TGAGTTACCA GAACACCATA TCCAGAGGCT CCCCCATGAT GAACAGAACT 
TCTGATGGTT CTTCCAGCAA GACTACCAGC CACGAGAGGA AGTCAGCTCT GACCCCAACC 
CAAAGAGAAA GTGTCCCAGC CAAGTCTCCA GTGCCTGCCG TGGACTCCGT CGTGAGTCAC 
AGTCCATTTG ACCCCCATCA TAGGAGTACC ACTGCAGGAG AGGTTTATCG GAGCCATCTT 
CCCACGCACT TGGATCCAGC CATGCCCTTT CACAGGGCTT TGGATCCTGC TGCTGCTTAC 
CTGTTTCAGA GACAGCTTTC ACCAACCCCA GGATACCCAA GTCAGTACCA GCTTTATGCA 
ATGGAGAATA CAAGACAGAC AATCCTAAAT GATTACATTA CCTCACAGCA GATGCAAGTG 
AATTTGCGCC CTGATGTTGC CAGGGGACTG TCCCCACGAG AGCAGCCACT GGGTCTCCCT 
TATCCAGCTA CAAGAGGAAT CATTGACCTG ACCAATATGC CTCCAACAAT CTTAGTGCCT 
CATGCAGGGG GGACAAGCAC CCCTCCCATG GACAGAATCA CTTATATCCC TGGTACACAG 
ATTACTTTCC CTCCGAGGCC ATACAATGCT GCTTCTTTGT CTCCAGGACA CCCGACACAC 
CTTGCAGCAG CTGCAAGTGC TGAGAGAGAA CGAGAGCGGG AAAGGGAGAA GGAGCGAGAG 
AGAGAGCGTG AGCGCGAGCG CGAACGTGAA CGCGAACGCG AACGTGAACG CGAACGCGAG 
CGTGAGCGTG AAAGGATCAC TGCTGCTCCC ACTGACCTCT ACCTACGACC AGGTTCAGAA 
CAGCCAGGCC GCCCTGGTAG CCACGGATAT GTTCGCTCCC CTTCCCCTTC AGTAAGAACT 
CAGGAGACCA TGTTGCAACA GAGACCCAGT GTTTTCCAGG GAACCAATGG AACCAGTGTG 
ATCACGCCTT TGGATCCAAC TGCTCAGCTA CGAATCATGC CACTGCCTTC TGGGGGCCCT 
TCCATAAGTC AAGGCCTGCC AGCCTCCCGT TACAACACTG CTGCGGATGC CCTGGCTGCT 
CTTGTGGACG CTGCAGCTTC TGCACCCCAG ATGGATGTTT CCAAAACAAA AGAGAGTAAG 
CATGAAGCTG CCAGGTTAGA AGACAATGTG AGAAGCAGGT CAGCAGCAGT TAGTGAGCAG 
CAGCAGCTAG AGCAGAAAAA CCTGGAGGTG GAGAAGAGAT CTGTTCAGTG TGTGTGCACC 
TCTTCAGCCC TTCCAAGTGG CAAGCCCCAG CCTCATGCCT CCGTAGTGTA TTCTGAGGCT 
GGGAAAGATA AAGGGCCTCC TCCAAAATCC AGATATGAGG AAGAGCTAAG GACCCGAGGG 
AAGACTACCA TTACTGCAGC TAACTTCATA GACGTGATCA TCACCCGGCA AATTGCCTCG 
GACAAGGATG CAAGGGAACG TGGCTCTCAA AGTTCAGACT CTTCTAGTAG CTTGTCTTCT 
CACAGGTATG AAGCACCTAG TGATGCTATT GAGGTGATAA GTCCTGCCAG CTCACCTGCA 
CCACCCCAGG AAAAACCACA GGCCTATCAG CCAGAGATGG TTAAGGCAAA TCAAGCAGAA 
AATGAGTCCC CTCAACAGTA TGAAGGACCA CTGCATCATT ATCGGTCCCA GCAGGGATCA 
CCGTCTCCAC AGCAACAGCC ACCACTGCCC CCATCGTCCC AGGCAGAGGG AATGGGACAG 
GTGCCCAGGA CCCATCGACT GATCACACTT GCTGACCACA TCTGTCAAAT TATCACACAA 
GATTTTGCTA GAAATCAAGT TCCCTCGCAG CCTTCTACTT CTACATTCCA AACTTCACCA 
TCTGCTTTGT CGTCCACACC TGTAAGAACT AAACCGTCAA GTCGCTACAG CCCAGAGTCT 
CAGTCTCAGA CTGTCTTGCA TCCCAGACCA GGTCCTAGAG TCTCTCCAGA AAATCTTGTG 
GATAAATCCC GGGGAAGCAG GCCTGGAAAA TCCCCAGAGA GGAGTCACAT CCCATCGGAG 
CCCTATGAGC CCATCTCCCC ACCCCAAGGT CCTGCTGTGC ATGAGAAGCA GGACAGCATG 
CTGCTCTTGT CACAAAGGGG AATGGATCCT GCCGAGCAAA GGAGTGATTC TCGATCACCA 
GGAAGTATAA GCTACTTGCC TTCATTCTTC ACCAAGCTTG AAAGCACATC ACCCATGGTT 
AAATCAAAGA AGCAGGAAAT TTTTCGTAAG TTGAACTCCT CTGGTGGAGG TGACTCTGAT 
ATGGCAGCTG CTCAGCCAGG AACAGAGATC TTCAATCTGC CAGCAGTTAC TACATCAGGT 
GCAGTAAGCT CAAGAAGCCA TTCTTTTGCT GATCCTGCCA GTAATCTTGG TCTAGAAGAC 
ATCATCAGAA AAGCTCTCAT GGGAAGTTTC GATGACAAAG TTGAAGATCA TGGTGTTGTC 
ATGCCTCATC CTGTGGGAGT TGTCCCTGGT AGTGCTAGCA CCTCAGTTGT GACGAGCAGT 
GAGACACGGA GAGATGAAGG GGACCCATCA CCTCATTCAG GAGTGTGCAA ACCAAAGCTG 
ATCAACAAAT CGAACAGCAG GAAGTCTAAA TCTCCTATTC CTGGGCAGAA CTACTTAGGA 
ACTGAAAGGC CTTCTTCTGT CTCCTCTGTA CATTCAGAGG GTGATTACCA CAGGCAGACA 
CCAGGATGGG CTTGGGAAGA CAGGCCGTCT TCAACAGGCT CCACTCAGTT CCCTTACAAC 
CCTCTGACCA TCCGGATGCT GAGCAGTACC CCGCCAACCC CGATCGCCTG TGCCCCGTCA 
GCCATCACCC AGGCAGCTCC GCATCAACAG AGCCGCATCT GGGAGCGGGA GCCGGCCCCG 
CTCCTCTCAG CACAGTATGA GACACTGTCT GACAGTGACG ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001258032.1
CDS	230..7474
Translation	MSSSGYPPNQGAFSTEQSRYPSQSVQYTFPSTRHQQEFAVPDYRSSHIEVSQASQLLQQQQQQQQLRRRPSLLSEFHPGSDRPQERRTGYEQFHSGPSPVDHDSLESKRPRLEPVSDAHFQRVSAAVLPLVHTLPEGLRASADAKKDSAFGGKHEAPSSPLAGQPCGDDQNASPSKLSKEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQIIYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRNHARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAEQRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEEDKAEKMEKKEEEKKDDEEKDEKEESKETTKEKDRTEATAEETEEREQVTPRGRKTANSQGRRKGRITRSMTSEAAAASAAAAATEEPPPPLPPPPEPVSTEPVETSRWTEEEMEVAKKGNIQQCIIYNSASRKPREERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEGAENSSDTESAPSPSPVEAAKSSEDSSENAASRGNTEPVAELEATTDPAPCASPSSAVPTTKPAESESVEAQVTDSASVETAEPMDVDHEECGAQGSSVLDPPAPTKADSVDPEIQVPENTASKGEGDAKDRDLESASEKTEARDEDLVVAEQMQRPEPQSDNDSSATCSADEDVDGEPERQRVFPMDAKPSLLNPPGSILISSPIKPNPLDLPQLQHRAAVIPPMVSCTPCNIPIGTPVSGYALYQRHIKAMHESALLEEQRQRQEQIDLECRSSTSPCGTSKSPNREWEVLQPAPHQVITNLPEGVRLPTTRPTRPPPPLIPSSKTTVASEKPSFIMGGSISQGTPGTYLTSHSQAYTPEAAKPSVGSISLGLPRQQESTKSAPLTYIKQEEFSPRSQNSQPEGLLVRAQHEGVVRGTAGAVQEGSITRGTPASKISVESISSLRGSITQGTPALPQAGIPTEALVKGPVSRMPIEESSPEKVREEAASKGHVIYEGKSGHILSYDNIKNAREGTRSPRTAHEMSLKRSYESVEGNVKQGMSMRESPVSAAPLEERTVLSGSIMQGTPRATAESFEDGLKYPKQIKRESPPSRAFEGAITKGKPYDGITTIKEMGRSIHEIPRQDILTQESRKTPEVVQSTRPIIEGSISQGTPIKFDNNSGQSAIKHNVKSLITGPSKLPRGMLEIVPENIKVVERGKYEDVKAGEPVRPRHTSVVSSGPSVLRSTLHEAPKAQLSPGIYDDSSARRTPVSYQNTISRGSPMMNRTSDGSSSKTTSHERKSALTPTQRESVPAKSPVPAVDSVVSHSPFDPHHRSTTAGEVYRSHLPTHLDPAMPFHRALDPAAAYLFQRQLSPTPGYPSQYQLYAMENTRQTILNDYITSQQMQVNLRPDVARGLSPREQPLGLPYPATRGIIDLTNMPPTILVPHAGGTSTPPMDRITYIPGTQITFPPRPYNAASLSPGHPTHLAAAASAEREREREREKERERERERERERERERERERERERERERITAAPTDLYLRPGSEQPGRPGSHGYVRSPSPSVRTQETMLQQRPSVFQGTNGTSVITPLDPTAQLRIMPLPSGGPSISQGLPASRYNTAADALAALVDAAASAPQMDVSKTKESKHEAARLEDNVRSRSAAVSEQQQLEQKNLEVEKRSVQCVCTSSALPSGKPQPHASVVYSEAGKDKGPPPKSRYEEELRTRGKTTITAANFIDVIITRQIASDKDARERGSQSSDSSSSLSSHRYEAPSDAIEVISPASSPAPPQEKPQAYQPEMVKANQAENESPQQYEGPLHHYRSQQGSPSPQQQPPLPPSSQAEGMGQVPRTHRLITLADHICQIITQDFARNQVPSQPSTSTFQTSPSALSSTPVRTKPSSRYSPESQSQTVLHPRPGPRVSPENLVDKSRGSRPGKSPERSHIPSEPYEPISPPQGPAVHEKQDSMLLLSQRGMDPAEQRSDSRSPGSISYLPSFFTKLESTSPMVKSKKQEIFRKLNSSGGGDSDMAAAQPGTEIFNLPAVTTSGAVSSRSHSFADPASNLGLEDIIRKALMGSFDDKVEDHGVVMPHPVGVVPGSASTSVVTSSETRRDEGDPSPHSGVCKPKLINKSNSRKSKSPIPGQNYLGTERPSSVSSVHSEGDYHRQTPGWAWEDRPSSTGSTQFPYNPLTIRMLSSTPPTPIACAPSAITQAAPHQQSRIWEREPAPLLSAQYETLSDSDD

Target ORF information:

RefSeq Version	NM_001271103.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus nuclear receptor co-repressor 1 (Ncor1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001271103.1

ORF Insert Sequence:

ATGTCAAGTT CAGGTTACCC TCCCAACCAA GGAGCTTTCA GCACAGAGCA AAGTCGTTAT 
CCTTCACAGT CTGTCCAGTA TACCTTTCCC AGTACCCGGC ACCAGCAGGA ATTTGCAGTT 
CCTGACTATC GCTCTTCTCA CATCGAAGTT AGTCAGGCAT CGCAGCTCTT ACAGCAGCAG 
CAGCAGCAGC AGCAGCTTCG AAGGCGACCT TCCTTGCTTT CAGAATTTCA CCCAGGTTCT 
GACAGGCCTC AAGAGAGAAG AACTGGATAT GAACAGTTTC ACTCAGGACC CTCACCAGTG 
GATCATGATT CCTTGGAGTC CAAGCGTCCA CGCCTGGAGC CAGTTTCTGA TGCCCATTTC 
CAGCGTGTTA GTGCTGCGGT TTTACCTTTA GTTCACACGC TGCCAGAGGG GTTGAGGGCG 
TCTGCAGATG CTAAGAAGGA TTCGGCATTT GGAGGCAAAC ATGAAGCTCC ATCCTCTCCA 
TTGGCTGGGC AACCATGTGG AGATGATCAA AACGCTTCAC CTTCAAAGCT CTCAAAGGAA 
GAGTTAATAC AGAGTATGGA CCGGGTAGAC AGAGAGATTG CAAAAGTAGA GCAGCAGATC 
CTTAAATTGA AAAAGAAACA ACAACAGCTA GAAGAAGAAG CAGCTAAGCC TCCTGAGCCG 
GAGAAGCCTG TGTCCCCTCC TCCTGTGGAA CAGAAACACC GTAGTATTGT CCAAATTATT 
TATGATGAGA ATCGGAAAAA AGCTGAAGAA GCTCATAAAA TATTTGAAGG TCTTGGCCCA 
AAAGTTGAAT TGCCACTCTA TAACCAGCCG TCAGATACCA AGGTGTACCA TGAGAACATC 
AAGACAAACC AGGTGATGAG GAAAAAACTC ATTTTATTTT TTAAAAGAAG AAATCATGCA 
AGAAAACAAA GGGAACAAAA AATCTGCCAG CGTTATGATC AACTCATGGA GGCATGGGAG 
AAAAAAGTGG ACAGAATAGA AAATAATCCT CGGAGGAAAG CAAAAGAAAG CAAAACAAGG 
GAATACTATG AGAAGCAGTT TCCAGAAATT CGAAAACAAA GAGAACAACA AGAAAGATTT 
CAGCGAGTTG GTCAGAGGGG AGCTGGTCTT TCAGCCACCA TTGCTAGGAG TGAGCATGAG 
ATTTCCGAAA TTATTGATGG CCTTTCTGAG CAGGAGAATA ATGAGAAACA AATGCGGCAG 
CTTTCTGTGA TTCCCCCGAT GATGTTTGAT GCAGAACAAA GAAGGGTCAA GTTCATCAAT 
ATGAATGGGC TCATGGAGGA TCCAATGAAG GTTTATAAAG ACAGACAGTT TATGAATGTT 
TGGACTGACC ACGAAAAGGA GATCTTTAAG GACAAGTTTA TCCAGCACCC AAAAAACTTT 
GGACTAATTG CATCCTATTT GGAAAGGAAG AGCGTGCCTG ATTGTGTTTT ATATTACTAT 
TTAACCAAGA AAAACGAGAA TTATAAAGCC CTTGTGAGAA GAAATTATGG GAAACGCAGA 
GGCAGAAATC AGCAGATTGC CCGTCCCTCA CAAGAAGAAA AAGTAGAAGA AAAAGAAGAG 
GATAAAGCAG AAAAAATGGA GAAAAAGGAA GAAGAAAAGA AGGATGATGA AGAAAAAGAT 
GAGAAGGAAG AGTCTAAAGA AACAACCAAG GAAAAGGATA GAACAGAAGC CACAGCAGAA 
GAAACTGAGG AGAGAGAGCA GGTCACTCCA AGGGGGCGAA AGACTGCTAA CAGCCAAGGG 
CGTCGGAAGG GCCGGATCAC CAGGTCCATG ACAAGTGAAG CTGCAGCTGC CAGTGCTGCT 
GCTGCAGCCA CTGAGGAGCC CCCTCCACCG CTGCCACCAC CCCCAGAGCC CGTTTCTACA 
GAACCAGTTG AGACTTCAAG ATGGACGGAA GAAGAAATGG AAGTTGCTAA AAAAGGTAAT 
ATACAGCAAT GTATAATATA CAACAGTGCT TCACGAAAAC CCCGTGAGGA ACGAGATGTG 
TCTCAGTGTG AAAGTGTTGC TTCCACTGTG TCTGCCCAGG AGGATGAAGA TATTGAAGCC 
TCGAATGAGG AGGAGAATCC AGAAGATAGT GAAGGTGCTG AAAATAGTTC TGATACAGAA 
AGTGCTCCCT CTCCTTCACC AGTTGAAGCT GCCAAGTCCA GTGAAGACAG CAGTGAAAAT 
GCTGCTTCTC GAGGAAACAC CGAACCTGTG GCTGAGCTTG AGGCCACCAC TGACCCTGCA 
CCCTGTGCAT CTCCCTCTTC AGCAGTTCCA ACCACAAAAC CAGCAGAAAG TGAAAGCGTG 
GAGGCCCAGG TGACTGACAG CGCCAGTGTG GAGACCGCAG AGCCGATGGA TGTAGACCAT 
GAGGAGTGCG GTGCCCAAGG CAGTTCTGTT CTTGATCCAC CAGCCCCTAC CAAAGCTGAC 
TCCGTGGACC CAGAAATACA GGTACCAGAA AACACTGCAT CTAAAGGTGA AGGGGATGCC 
AAGGACAGAG ACTTGGAGAG CGCCAGTGAG AAGACAGAGG CTAGAGATGA AGACTTGGTA 
GTGGCTGAGC AGATGCAGAG GCCTGAACCA CAGTCAGACA ACGACTCCAG TGCCACATGC 
AGTGCAGACG AGGATGTCGA TGGAGAGCCA GAGAGGCAGA GAGTGTTTCC CATGGATGCA 
AAGCCTTCAC TGTTAAATCC TCCAGGATCA ATACTAATCT CATCCCCCAT TAAACCAAAC 
CCATTGGATC TGCCACAGCT TCAGCATCGA GCTGCTGTTA TTCCACCAAT GGTTTCTTGC 
ACCCCATGTA ATATACCAAT TGGAACACCT GTAAGTGGCT ATGCTCTTTA CCAACGGCAC 
ATTAAGGCCA TGCATGAGTC AGCACTCCTG GAGGAACAGC GGCAGAGGCA AGAACAGATA 
GACTTGGAGT GCAGAAGTTC TACAAGCCCG TGTGGCACTT CTAAGAGTCC AAACAGGGAA 
TGGGAAGTCC TCCAACCTGC TCCACATCAA GTGATAACTA ACCTTCCTGA AGGGGTTCGG 
CTTCCAACAA CACGACCAAC CAGGCCACCA CCTCCCCTCA TCCCATCGTC CAAAACCACA 
GTAGCATCAG AAAAACCATC CTTTATAATG GGAGGGTCCA TCTCACAGGG AACTCCTGGC 
ACTTACTTGA CTTCTCATAG TCAGGCTTAT ACTCCGGAAG CAGCTAAGCC CTCAGTGGGG 
TCTATCTCTC TTGGATTGCC ACGGCAGCAG GAATCTACCA AGTCAGCTCC TTTGACCTAC 
ATCAAGCAGG AAGAATTTTC TCCACGAAGC CAAAACTCAC AGCCTGAGGG TTTATTGGTG 
AGAGCGCAGC ATGAAGGTGT GGTCAGAGGC ACTGCAGGGG CTGTCCAAGA AGGAAGTATA 
ACTCGGGGAA CTCCAGCCAG CAAGATCTCA GTGGAGAGCA TTTCATCCTT GCGGGGCTCT 
ATTACCCAGG GGACCCCAGC TCTGCCCCAG GCTGGCATAC CAACAGAGGC TTTGGTGAAG 
GGACCTGTTT CCAGGATGCC AATTGAGGAA AGCAGTCCTG AGAAGGTCAG AGAGGAAGCT 
GCATCCAAAG GCCATGTCAT CTATGAAGGC AAAAGTGGAC ATATCTTATC ATATGACAAT 
ATTAAGAATG CCCGAGAAGG GACTCGGAGT CCAAGAACAG CTCATGAAAT GAGTTTAAAA 
AGAAGCTATG AGTCAGTGGA AGGAAATGTA AAGCAAGGCA TGTCGATGAG GGAGTCTCCT 
GTGTCAGCAG CACCTTTAGA GGAAAGGACT GTGCTGTCTG GTTCCATAAT GCAGGGCACA 
CCTAGAGCAA CAGCCGAAAG CTTTGAAGAT GGCCTTAAAT ACCCCAAACA GATAAAAAGG 
GAAAGCCCTC CTAGTCGAGC ATTTGAAGGT GCCATTACCA AAGGAAAACC ATACGATGGC 
ATCACCACCA TCAAAGAAAT GGGGCGTTCC ATTCATGAAA TTCCAAGACA AGATATTCTA 
ACTCAGGAAA GCCGGAAAAC TCCAGAAGTG GTCCAGAGCA CGAGGCCAAT AATTGAGGGT 
TCCATTTCCC AGGGCACACC AATAAAATTT GACAACAACT CAGGTCAATC AGCTATCAAA 
CACAATGTGA AGTCCTTAAT CACAGGGCCT AGCAAACTAC CCCGAGGAAT GCTGGAAATT 
GTACCAGAAA ACATAAAAGT AGTAGAACGG GGAAAATATG AGGACGTGAA AGCAGGCGAA 
CCAGTGCGAC CCCGGCACAC GTCAGTGGTG AGCTCTGGCC CCTCCGTTCT CAGGTCTACA 
CTTCATGAAG CTCCCAAAGC ACAGTTGAGC CCGGGAATCT ATGATGACAG CAGTGCTCGC 
AGGACTCCTG TGAGTTACCA GAACACCATA TCCAGAGGCT CCCCCATGAT GAACAGAACT 
TCTGATGGTT CTTCCAGCAA GACTACCAGC CACGAGAGGA AGTCAGCTCT GACCCCAACC 
CAAAGAGAAA GTGTCCCAGC CAAGTCTCCA GTGCCTGCCG TGGACTCCGT CGTGAGTCAC 
AGTCCATTTG ACCCCCATCA TAGGAGTACC ACTGCAGGAG AGGTTTATCG GAGCCATCTT 
CCCACGCACT TGGATCCAGC CATGCCCTTT CACAGGGCTT TGGATCCTGC TGCTGCTTAC 
CTGTTTCAGA GACAGCTTTC ACCAACCCCA GGATACCCAA GTCAGTACCA GCTTTATGCA 
ATGGAGAATA CAAGACAGAC AATCCTAAAT GATTACATTA CCTCACAGCA GATGCAAGTG 
AATTTGCGCC CTGATGTTGC CAGGGGACTG TCCCCACGAG AGCAGCCACT GGGTCTCCCT 
TATCCAGCTA CAAGAGGAAT CATTGACCTG ACCAATATGC CTCCAACAAT CTTAGTGCCT 
CATGCAGGGG GGACAAGCAC CCCTCCCATG GACAGAATCA CTTATATCCC TGGTACACAG 
ATTACTTTCC CTCCGAGGCC ATACAATGCT GCTTCTTTGT CTCCAGGACA CCCGACACAC 
CTTGCAGCAG CTGCAAGTGC TGAGAGAGAA CGAGAGCGGG AAAGGGAGAA GGAGCGAGAG 
AGAGAGCGTG AGCGCGAGCG CGAACGTGAA CGCGAACGCG AACGTGAACG CGAACGCGAG 
CGTGAGCGTG AAAGGATCAC TGCTGCTCCC ACTGACCTCT ACCTACGACC AGGTTCAGAA 
CAGCCAGGCC GCCCTGGTAG CCACGGATAT GTTCGCTCCC CTTCCCCTTC AGTAAGAACT 
CAGGAGACCA TGTTGCAACA GAGACCCAGT GTTTTCCAGG GAACCAATGG AACCAGTGTG 
ATCACGCCTT TGGATCCAAC TGCTCAGCTA CGAATCATGC CACTGCCTTC TGGGGGCCCT 
TCCATAAGTC AAGGCCTGCC AGCCTCCCGT TACAACACTG CTGCGGATGC CCTGGCTGCT 
CTTGTGGACG CTGCAGCTTC TGCACCCCAG ATGGATGTTT CCAAAACAAA AGAGAGTAAG 
CATGAAGCTG CCAGGTTAGA AGACAATGTG AGAAGCAGGT CAGCAGCAGT TAGTGAGCAG 
CAGCAGCTAG AGCAGAAAAA CCTGGAGGTG GAGAAGAGAT CTGTTCAGTG TGTGTGCACC 
TCTTCAGCCC TTCCAAGTGG CAAGCCCCAG CCTCATGCCT CCGTAGTGTA TTCTGAGGCT 
GGGAAAGATA AAGGGCCTCC TCCAAAATCC AGATATGAGG AAGAGCTAAG GACCCGAGGG 
AAGACTACCA TTACTGCAGC TAACTTCATA GACGTGATCA TCACCCGGCA AATTGCCTCG 
GACAAGGATG CAAGGGAACG TGGCTCTCAA AGTTCAGACT CTTCTAGTAG CTTGTCTTCT 
CACAGGTATG AAGCACCTAG TGATGCTATT GAGGTGATAA GTCCTGCCAG CTCACCTGCA 
CCACCCCAGG AAAAACCACA GGCCTATCAG CCAGAGATGG TTAAGGCAAA TCAAGCAGAA 
AATGAGTCCC CTCAACAGTA TGAAGGACCA CTGCATCATT ATCGGTCCCA GCAGGGATCA 
CCGTCTCCAC AGCAACAGCC ACCACTGCCC CCATCGTCCC AGGCAGAGGG AATGGGACAG 
GTGCCCAGGA CCCATCGACT GATCACACTT GCTGACCACA TCTGTCAAAT TATCACACAA 
GATTTTGCTA GAAATCAAGT TCCCTCGCAG CCTTCTACTT CTACATTCCA AACTTCACCA 
TCTGCTTTGT CGTCCACACC TGTAAGAACT AAACCGTCAA GTCGCTACAG CCCAGAGTCT 
CAGTCTCAGA CTGTCTTGCA TCCCAGACCA GGTCCTAGAG TCTCTCCAGA AAATCTTGTG 
GATAAATCCC GGGGAAGCAG GCCTGGAAAA TCCCCAGAGA GGAGTCACAT CCCATCGGAG 
CCCTATGAGC CCATCTCCCC ACCCCAAGGT CCTGCTGTGC ATGAGAAGCA GGACAGCATG 
CTGCTCTTGT CACAAAGGGG AATGGATCCT GCCGAGCAAA GGAGTGATTC TCGATCACCA 
GGAAGTATAA GCTACTTGCC TTCATTCTTC ACCAAGCTTG AAAGCACATC ACCCATGGTT 
AAATCAAAGA AGCAGGAAAT TTTTCGTAAG TTGAACTCCT CTGGTGGAGG TGACTCTGAT 
ATGGCAGCTG CTCAGCCAGG AACAGAGATC TTCAATCTGC CAGCAGTTAC TACATCAGGT 
GCAGTAAGCT CAAGAAGCCA TTCTTTTGCT GATCCTGCCA GTAATCTTGG TCTAGAAGAC 
ATCATCAGAA AAGCTCTCAT GGGAAGTTTC GATGACAAAG TTGAAGATCA TGGTGTTGTC 
ATGCCTCATC CTGTGGGAGT TGTCCCTGGT AGTGCTAGCA CCTCAGTTGT GACGAGCAGT 
GAGACACGGA GAGATGAAGG GGACCCATCA CCTCATTCAG GAGTGTGCAA ACCAAAGCTG 
ATCAACAAAT CGAACAGCAG GAAGTCTAAA TCTCCTATTC CTGGGCAGAA CTACTTAGGA 
ACTGAAAGGC CTTCTTCTGT CTCCTCTGTA CATTCAGAGG GTGATTACCA CAGGCAGACA 
CCAGGATGGG CTTGGGAAGA CAGGCCGTCT TCAACAGGCT CCACTCAGTT CCCTTACAAC 
CCTCTGACCA TCCGGATGCT GAGCAGTACC CCGCCAACCC CGATCGCCTG TGCCCCGTCA 
GCCATCACCC AGGCAGCTCC GCATCAACAG AGCCGCATCT GGGAGCGGGA GCCGGCCCCG 
CTCCTCTCAG CACAGTATGA GACACTGTCT GACAGTGACG ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

NCoR negatively regulates adipogenic differentiation of mesenchymal stem cells.
In vitro cellular & developmental biology. Animal51(7)749-58(2015 Aug)
Hong-Wei G,Lan L,De-Guo X,Zhong-Hao L,Peng R,Zhi-Qiang L,Guo-Qiang S,Ming-Zhi G

Circadian regulation of Tshb gene expression by Rev-Erb? (NR1D1) and nuclear corepressor 1 (NCOR1).
The Journal of biological chemistry289(24)17070-7(2014 Jun)
Aninye IO,Matsumoto S,Sidhaye AR,Wondisford FE

Thyroid hormone signaling in vivo requires a balance between coactivators and corepressors.
Molecular and cellular biology34(9)1564-75(2014 May)
Vella KR,Ramadoss P,Costa-E-Sousa RH,Astapova I,Ye FD,Holtz KA,Harris JC,Hollenberg AN

SMRT-mediated co-shuttling enables export of class IIa HDACs independent of their CaM kinase phosphorylation sites.
Journal of neurochemistry124(1)26-35(2013 Jan)
Soriano FX,Chawla S,Skehel P,Hardingham GE

A molecular mechanism underlying ovarian dysfunction of polycystic ovary syndrome: hyperandrogenism induces epigenetic alterations in the granulosa cells.
Journal of molecular medicine (Berlin, Germany)90(8)911-23(2012 Aug)
Qu F,Wang FF,Yin R,Ding GL,El-Prince M,Gao Q,Shi BW,Pan HH,Huang YT,Jin M,Leung PC,Sheng JZ,Huang HF

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Ncor1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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